Nudt6 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Nudt6
Entrez Gene ID	207120
Full Name	nudix hydrolase 6
Synonyms	Gfg
General protein information	Preferred Names nudix hydrolase 6 Names nucleoside diphosphate-linked moiety X motif 6 antisense basic fibroblast growth factor nudix (nucleoside diphosphate linked moiety X)-type motif 6 nudix motif 6
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 2 Map Location: 2q25
Summary	plays a role in the post-transcriptional regulation of FGF-2 [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_008760905.2	XP_008759127.1	nucleoside diphosphate-linked moiety X motif 6 isoform X1
NM_181363.2	NP_852028.1	nucleoside diphosphate-linked moiety X motif 6 precursor

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Nudt6	NP_852028.1
Oryza sativa (rice)	Os04g0547900	NP_001053476.1
Danio rerio (zebrafish)	nudt6	NP_001082991.1
	NUDT6	XP_001103787.1
Canis lupus familiaris (dog)	NUDT6	XP_540961.3
Mus musculus (house mouse)	Nudt6	NP_705789.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP012857	XP_307652.4
Arabidopsis thaliana (thale cress)	NUDT8	NP_568680.1
Homo sapiens (human)	NUDT6	NP_009014.2
Pan troglodytes (chimpanzee)	NUDT6	XP_517426.2
Gallus gallus (chicken)	NUDT6	XP_003641250.2
Drosophila melanogaster (fruit fly)	CG8128	NP_573053.2
Bos taurus (cattle)	NUDT6	NP_001099120.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP012590	XP_307498.3
Xenopus tropicalis (tropical clawed frog)	nudt6	XP_004911171.1

Gene Ontology
Bibliography

Related articles in PubMed

The fibroblast growth factor-2 antisense gene inhibits nuclear accumulation of FGF-2 and delays cell cycle progression in C6 glioma cells.
Baguma-Nibasheka M, Li AW, Murphy PR
Molecular and cellular endocrinology267(1-2)127-36(2007 Mar)

The endogenous fibroblast growth factor-2 antisense gene product regulates pituitary cell growth and hormone production.
Asa SL, Ramyar L, Murphy PR, Li AW, Ezzat S
Molecular endocrinology (Baltimore, Md.)15(4)589-99(2001 Apr)

Expression of alternatively spliced FGF-2 antisense RNA transcripts in the central nervous system: regulation of FGF-2 mRNA translation.
Li AW, Murphy PR
Molecular and cellular endocrinology162(1-2)69-78(2000 Apr)

Characterization and tissue-specific expression of the rat basic fibroblast growth factor antisense mRNA and protein.
Knee R, Li AW, Murphy PR
Proceedings of the National Academy of Sciences of the United States of America94(10)4943-7(1997 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The results suggest that the endogenous FGF antisense RNA may play a significant functional role in the regulation of FGF-2 dependent cell proliferation in FGF-2 expressing cells.
Title: The fibroblast growth factor-2 antisense gene inhibits nuclear accumulation of FGF-2 and delays cell cycle progression in C6 glioma cells.

The following Nudt6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Nudt6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa04230	NM_181363.2 Latest version!	Rattus norvegicus nudix hydrolase 6 (Nudt6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00
ORa44387	XM_008760905.2 Latest version!	Rattus norvegicus nudix hydrolase 6 (Nudt6), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Nudt6 ( NM_181363.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_852028.1 Rattus norvegicus nudix hydrolase 6 (Nudt6), mRNA.

Price & Availability↑

CloneID	ORa04230
Clone ID Related Accession (Same CDS sequence)	NM_181363.2
Accession Version	NM_181363.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 942bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-22
Organism	Rattus norvegicus(Norway rat)
Product	nucleoside diphosphate-linked moiety X motif 6 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from U58289.1. On Jun 3, 2003 this sequence version replaced NM_181363.1. ##Evidence-Data-START## Transcript exon combination :: U58289.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGTGGTGGG CGAGCAGAGC GCGATGGTTG TTCTCGGCTT TGCTCGACGT GGGCGGAGTC 
GGACTCCGGG CTAGGCGGCG CACTGCCTCG AGCGGCCTGG AGATCACGGG CTCCTGCGGG 
GGCGAGCTAC AAGGCGAGCT GGACAGATTT GGGGGCATCT CGGTGCACTT GTCGCGGCAC 
CGCACCCTGC ACCGGCTGGA TGCCGCCGCC TTCCGGAGGC TCTTGCAGGC CGCCATTCAG 
CAGTGGCGAG CGGAAGGAAG GATCGCTGCA TGGCTGCACA TCCCCATCCT GCAGAGCCAC 
TTCATCGCCC CTGCTGCCTC TCTGGGCTTC TGCTTCCACC ACGCAGAACC GCACTTGTCA 
ACGCTGACTC TGTGGTTGGG AGAAGGACCC AGCAGACTCC CGGGGTATGC CACACACCAA 
GTAGGGGTTG CAGGTGCCGT ATTTGATGTT AGCACCAGGA AAGTACTGGT TGTACAAGAT 
CGAAATAAAT TGAAAAACAT GTGGAAGTTT CCAGGAGGCC TGTCAGAGCC TGGAGAAGAT 
ATTGGAGACA CAGCAGTCCG AGAGGTGTTT GAAGAGACTG GTGTCAAGTC AGAATTCAGG 
TCTCTGTTGA GCATCCGGCA GCAACACAGG AGCCCTGGGG CCTTTGGGAT GTCAGACATG 
TACCTGATCT GCCGCCTGCA GCCGCGTTCC TTCACCATCA ACTTCTGCCA GCAGGAATGC 
TTGAAGTGTG AATGGATGGA TCTAGAAAGC CTGGCCAGGA CTAAACACAC AACCCCCATC 
ACCAGCAGGG TGGCTAGGCT ACTACTATAC GGACACAGGG AAGGGTTTGA CAAGATTGAC 
CTCAGCATGG AGGAACTCCC TGCAGTATAC ACAGGCCTGT TCTACAAGCT CTACCACAGG 
GGACTGCCTG AGAGGTACAA GGCTGAAATG GGAACAGATT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_852028.1
CDS	34..975
Translation	MWWASRARWLFSALLDVGGVGLRARRRTASSGLEITGSCGGELQGELDRFGGISVHLSRHRTLHRLDAAAFRRLLQAAIQQWRAEGRIAAWLHIPILQSHFIAPAASLGFCFHHAEPHLSTLTLWLGEGPSRLPGYATHQVGVAGAVFDVSTRKVLVVQDRNKLKNMWKFPGGLSEPGEDIGDTAVREVFEETGVKSEFRSLLSIRQQHRSPGAFGMSDMYLICRLQPRSFTINFCQQECLKCEWMDLESLARTKHTTPITSRVARLLLYGHREGFDKIDLSMEELPAVYTGLFYKLYHRGLPERYKAEMGTD

Target ORF information:

RefSeq Version	NM_181363.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus nudix hydrolase 6 (Nudt6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_181363.2

ORF Insert Sequence:

ATGTGGTGGG CGAGCAGAGC GCGATGGTTG TTCTCGGCTT TGCTCGACGT GGGCGGAGTC 
GGACTCCGGG CTAGGCGGCG CACTGCCTCG AGCGGCCTGG AGATCACGGG CTCCTGCGGG 
GGCGAGCTAC AAGGCGAGCT GGACAGATTT GGGGGCATCT CGGTGCACTT GTCGCGGCAC 
CGCACCCTGC ACCGGCTGGA TGCCGCCGCC TTCCGGAGGC TCTTGCAGGC CGCCATTCAG 
CAGTGGCGAG CGGAAGGAAG GATCGCTGCA TGGCTGCACA TCCCCATCCT GCAGAGCCAC 
TTCATCGCCC CTGCTGCCTC TCTGGGCTTC TGCTTCCACC ACGCAGAACC GCACTTGTCA 
ACGCTGACTC TGTGGTTGGG AGAAGGACCC AGCAGACTCC CGGGGTATGC CACACACCAA 
GTAGGGGTTG CAGGTGCCGT ATTTGATGTT AGCACCAGGA AAGTACTGGT TGTACAAGAT 
CGAAATAAAT TGAAAAACAT GTGGAAGTTT CCAGGAGGCC TGTCAGAGCC TGGAGAAGAT 
ATTGGAGACA CAGCAGTCCG AGAGGTGTTT GAAGAGACTG GTGTCAAGTC AGAATTCAGG 
TCTCTGTTGA GCATCCGGCA GCAACACAGG AGCCCTGGGG CCTTTGGGAT GTCAGACATG 
TACCTGATCT GCCGCCTGCA GCCGCGTTCC TTCACCATCA ACTTCTGCCA GCAGGAATGC 
TTGAAGTGTG AATGGATGGA TCTAGAAAGC CTGGCCAGGA CTAAACACAC AACCCCCATC 
ACCAGCAGGG TGGCTAGGCT ACTACTATAC GGACACAGGG AAGGGTTTGA CAAGATTGAC 
CTCAGCATGG AGGAACTCCC TGCAGTATAC ACAGGCCTGT TCTACAAGCT CTACCACAGG 
GGACTGCCTG AGAGGTACAA GGCTGAAATG GGAACAGATT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Nudt6 ( XM_008760905.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008759127.1 Rattus norvegicus nudix hydrolase 6 (Nudt6), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa44387
Clone ID Related Accession (Same CDS sequence)	XM_008760905.2
Accession Version	XM_008760905.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 444bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	nucleoside diphosphate-linked moiety X motif 6 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005101.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008760905.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTGGAAGT TTCCAGGAGG CCTGTCAGAG CCTGGAGAAG ATATTGGAGA CACAGCAGTC 
CGAGAGGTGT TTGAAGAGAC TGGTGTCAAG TCAGAATTCA GGTCTCTGTT GAGCATCCGG 
CAGCAACACA GGAGCCCTGG GGCCTTTGGG ATGTCAGACA TGTACCTGAT CTGCCGCCTG 
CAGCCGCGTT CCTTCACCAT CAACTTCTGC CAGCAGGAAT GCTTGAAGTG TGAATGGATG 
GATCTAGAAA GCCTGGCCAG GACTAAACAC ACAACCCCCA TCACCAGCAG GGTGGCTAGG 
CTACTACTAT ACGGACACAG GGAAGGGTTT GACAAGATTG ACCTCAGCAT GGAGGAACTC 
CCTGCAGTAT ACACAGGCCT GTTCTACAAG CTCTACCACA GGGGACTGCC TGAGAGGTAC 
AAGGCCGAAA TGGGAACAGA TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008759127.1
CDS	349..792
Translation	MWKFPGGLSEPGEDIGDTAVREVFEETGVKSEFRSLLSIRQQHRSPGAFGMSDMYLICRLQPRSFTINFCQQECLKCEWMDLESLARTKHTTPITSRVARLLLYGHREGFDKIDLSMEELPAVYTGLFYKLYHRGLPERYKAEMGTD

Target ORF information:

RefSeq Version	XM_008760905.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus nudix hydrolase 6 (Nudt6), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008760905.2

ORF Insert Sequence:

ATGTGGAAGT TTCCAGGAGG CCTGTCAGAG CCTGGAGAAG ATATTGGAGA CACAGCAGTC 
CGAGAGGTGT TTGAAGAGAC TGGTGTCAAG TCAGAATTCA GGTCTCTGTT GAGCATCCGG 
CAGCAACACA GGAGCCCTGG GGCCTTTGGG ATGTCAGACA TGTACCTGAT CTGCCGCCTG 
CAGCCGCGTT CCTTCACCAT CAACTTCTGC CAGCAGGAAT GCTTGAAGTG TGAATGGATG 
GATCTAGAAA GCCTGGCCAG GACTAAACAC ACAACCCCCA TCACCAGCAG GGTGGCTAGG 
CTACTACTAT ACGGACACAG GGAAGGGTTT GACAAGATTG ACCTCAGCAT GGAGGAACTC 
CCTGCAGTAT ACACAGGCCT GTTCTACAAG CTCTACCACA GGGGACTGCC TGAGAGGTAC 
AAGGCCGAAA TGGGAACAGA TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The fibroblast growth factor-2 antisense gene inhibits nuclear accumulation of FGF-2 and delays cell cycle progression in C6 glioma cells.
Molecular and cellular endocrinology267(1-2)127-36(2007 Mar)
Baguma-Nibasheka M,Li AW,Murphy PR

The endogenous fibroblast growth factor-2 antisense gene product regulates pituitary cell growth and hormone production.
Molecular endocrinology (Baltimore, Md.)15(4)589-99(2001 Apr)
Asa SL,Ramyar L,Murphy PR,Li AW,Ezzat S

Expression of alternatively spliced FGF-2 antisense RNA transcripts in the central nervous system: regulation of FGF-2 mRNA translation.
Molecular and cellular endocrinology162(1-2)69-78(2000 Apr)
Li AW,Murphy PR

Characterization and tissue-specific expression of the rat basic fibroblast growth factor antisense mRNA and protein.
Proceedings of the National Academy of Sciences of the United States of America94(10)4943-7(1997 May)
Knee R,Li AW,Murphy PR