Rph3a cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Rph3a
Entrez Gene ID	171039
Full Name	rabphilin 3A
General protein information	Preferred Names rabphilin 3A Names rabphilin-3A exophilin-1 rabphilin 3A homolog
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 12 Map Location: 12q16
Summary	binds Ca2+ and phospholipids [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_133518.1	NP_598202.1	rabphilin-3A
XM_006249379.3	XP_006249441.1	rabphilin-3A isoform X1
XM_006249380.3	XP_006249442.1	rabphilin-3A isoform X2
XM_006249381.3	XP_006249443.1	rabphilin-3A isoform X3

Pathways from BioSystems

Homologies

	RPH3A	XP_001110537.2
Homo sapiens (human)	RPH3A	NP_001137326.1
Mus musculus (house mouse)	Rph3a	NP_035416.1
Rattus norvegicus (Norway rat)	Rph3a	NP_598202.1
Gallus gallus (chicken)	RPH3A	XP_004945666.1
Drosophila melanogaster (fruit fly)	Rph	NP_572651.1
Xenopus tropicalis (tropical clawed frog)	LOC100487950	XP_002936460.2
Bos taurus (cattle)	RPH3A	NP_776879.1
Caenorhabditis elegans (roundworm)	rbf-1	NP_001022567.1
Pan troglodytes (chimpanzee)	RPH3A	XP_003952378.1
Canis lupus familiaris (dog)	RPH3A	XP_005636309.1
Danio rerio (zebrafish)	rph3ab	XP_691832.4

Gene Ontology
Bibliography

Related articles in PubMed

Rabphilin 3A: A novel target for the treatment of levodopa-induced dyskinesias.
Stanic J, Mellone M, Napolitano F, Racca C, Zianni E, Minocci D, Ghiglieri V, Thiolat ML, Li Q, Longhi A, De Rosa A, Picconi B, Bezard E, Calabresi P, Di Luca M, Usiello A, Gardoni F
Neurobiology of disease10854-64(2017 Dec)

Rabphilin 3A retains NMDA receptors at synaptic sites through interaction with GluN2A/PSD-95 complex.
Stanic J, Carta M, Eberini I, Pelucchi S, Marcello E, Genazzani AA, Racca C, Mulle C, Di Luca M, Gardoni F
Nature communications610181(2015 Dec)

Doc2 supports spontaneous synaptic transmission by a Ca(2+)-independent mechanism.
Pang ZP, Bacaj T, Yang X, Zhou P, Xu W, S?dhof TC
Neuron70(2)244-51(2011 Apr)

In-depth fluorescence lifetime imaging analysis revealing SNAP25A-Rabphilin 3A interactions.
Lee JD, Huang PC, Lin YC, Kao LS, Huang CC, Kao FJ, Lin CC, Yang DM
Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada14(6)507-18(2008 Dec)

Structural determinants for Ca2+ and phosphatidylinositol 4,5-bisphosphate binding by the C2A domain of rabphilin-3A.
Coudevylle N, Montaville P, Leonov A, Zweckstetter M, Becker S
The Journal of biological chemistry283(51)35918-28(2008 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Rph3A interacts with GluN2A and PSD-95 forming a complex that regulates NMDARs stabilization at postsynaptic membranes.
Title: Rabphilin 3A retains NMDA receptors at synaptic sites through interaction with GluN2A/PSD-95 complex.

Interactions of SNAP25A and RPH3A take place at cell surface during stimulated exocytosis.
Title: In-depth fluorescence lifetime imaging analysis revealing SNAP25A-Rabphilin 3A interactions.

Structural determinants for Ca2+ and phosphatidylinositol 4,5-bisphosphate binding by the C2A domain of rabphilin-3A.
Title: Structural determinants for Ca2+ and phosphatidylinositol 4,5-bisphosphate binding by the C2A domain of rabphilin-3A.

Three Rab3/27 effectors, Granuphilin, Noc2, and Rabphilin, in PC12 cells using fluorescence recovery after photobleaching of EGFP-tagged proteins.
Title: The Rab27 effector Rabphilin, unlike Granuphilin and Noc2, rapidly exchanges between secretory granules and cytosol in PC12 cells.

different PIP2 headgroup recognition modes suggest that PIP2 is a target of the C2A domain of rabphilin-3A while this phospholipid is an effector of the C2B domain
Title: The PIP2 binding mode of the C2 domains of rabphilin-3A.

The following Rph3a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Rph3a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa35052	XM_006249381.3 Latest version!	Rattus norvegicus rabphilin 3A (Rph3a), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
ORa00806	NM_133518.1 Latest version!	Rattus norvegicus rabphilin 3A (Rph3a), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
ORa35050	XM_006249379.3 Latest version!	Rattus norvegicus rabphilin 3A (Rph3a), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
ORa35051	XM_006249380.3 Latest version!	Rattus norvegicus rabphilin 3A (Rph3a), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Rph3a ( XM_006249381.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006249443.1 Rattus norvegicus rabphilin 3A (Rph3a), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa35052
Clone ID Related Accession (Same CDS sequence)	XM_006249381.3
Accession Version	XM_006249381.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1995bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	rabphilin-3A isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005111.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006249381.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACTGACA CTGTGGTGAA CCGTTGGATG TACCCTGGTG ATGGCCCACT GCAGTCAAAT 
GACAAGGAAC AGCTGCAGGC AGGATGGTCC GTCCATCCTG GAGCACAGAC GGACAGGCAG 
AGGAAGCAGG AAGAACTGAC AGACGAGGAG AAGGAGATAA TCAACCGGGT GATAGCTCGG 
GCAGAGAAGA TGGAAGCCAT GGAGCAGGAG CGCATCGGGC GCCTGGTGGA CCGTCTGGAG 
ACCATGAGGA AGAATGTAGC TGGAGATGGT GTGAACCGTT GCATCCTGTG CGGGGAACAG 
CTGGGCATGC TGGGCTCTGC GTGTGTCGTG TGTGAAGACT GTAAGAAGAA TGTCTGCACC 
AAGTGTGGGG TGGAGACCTC CAACAACCGT CCGCATCCAG TATGGCTCTG TAAGATCTGC 
CTTGAGCAGA GAGAGGTCTG GAAGCGCTCG GGAGCATGGT TCTTCAAGGG TTTCCCAAAA 
CAGGTCCTTC CACAGCCCAT GCCTATAAAG AAGACCAAGC CCCAGCAGCC TGCTGGTGAG 
CCGGCCACCC AGGAGCAGCC TACACCCGAG TCCAGGCATC CAGCCAGAGC TCCAGCTCGA 
GGTGACATGG AGGACAGGAG GGCCCCAGGA CAGAAGCCAG GCCCTGACCT CACCTCTGCT 
CCTGGACGAG GAAGCCATGG GCCTCCCACA CGCAGGGCCT CTGAGGCCCG GATGAGTACA 
ACCACCCGTG ATTCTGAGGG CTGGGACCAT GGTCATGGTG GGGGTGCTGG AGACACCAGC 
CGGAGCCCAG GAGGTGAGCA AGGTTTGAGG CGAGCTAACT CAGTCCAGGC CTCCCGCCCA 
GCTCCAGCCT CCATGCCAAG CCCGGCACCT CCTCAGCCCG TGCAGCCAGA GGCTCCTCCA 
AGTGACCCTG GCTATCCAGG GGCTGTTGCC CCAGCCCGGG AGGAGAGGAC AGGACCCACA 
GGGGGCTTCC AGGCAGCGCC CCACACTGCG GGTCCCTATT CCCAGGCGGC CCCTGCCCGC 
CAGCCACCGC CTGCTGAGGA AGAGGAGGAA GAAGCCAACA GCTATGACTC AGATGAAGCA 
ACCACACTGG GTGCCCTGGA ATTCAGCCTT CTCTATGACC AAGACAACAG CAACCTGCAG 
TGCACCATCA TCAGGGCGAA GGGACTGAAG CCCATGGACT CCAACGGCTT AGCGGATCCC 
TATGTGAAGC TGCATCTGCT GCCTGGAGCC AGCAAGTCCA ACAAGCTTCG TACAAAGACC 
CTGCGCAACA CCCGGAACCC TGTGTGGAAC GAGACGCTGC AGTATCATGG CATTACTGAG 
GAGGACATGC AGAGGAAGAC ACTCAGGATC TCCGTATGTG ACGAGGACAA GTTTGGCCAC 
AATGAGTTCA TTGGTGAGAC CAGGTTCTCG CTCAAGAAAC TGAAGGCGAA CCAGAGGAAA 
AACTTCAACA TCTGCCTGGA GCGGGTGATC CCGATGAAGC GCGCAGGAAC CACTGGGTCA 
GCACGTGGCA TGGCTCTCTA TGAGGAGGAG CAGGTGGAGC GGATCGGAGA CATAGAGGAA 
CGGGGCAAGA TCCTGGTGTC CCTCATGTAC AGCACGCAGC AGGGCGGCCT CATCGTGGGA 
ATTATCCGCT GTGTGCACCT GGCTGCCATG GACGCCAACG GCTACTCAGA CCCCTTCGTC 
AAGCTCTGGC TGAAACCGGA CATGGGGAAG AAAGCCAAGC ACAAGACTCA GATTAAAAAG 
AAGACCCTGA ATCCCGAGTT TAATGAGGAG TTCTTTTATG ATATCAAACA CAGCGACCTG 
GCCAAAAAGT CCCTGGATAT CTCAGTGTGG GACTACGACA TTGGCAAATC GAATGATTAC 
ATCGGAGGCT GCCAGCTGGG GATCTCGGCC AAGGGCGAGC GCTTGAAACA TTGGTATGAG 
TGTCTGAAGA ACAAAGACAA GAAGATTGAA CGTTGGCACC AACTGCAGAA CGAGAACCAC 
GTGTCGAGCG ACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006249443.1
CDS	554..2548
Translation	MTDTVVNRWMYPGDGPLQSNDKEQLQAGWSVHPGAQTDRQRKQEELTDEEKEIINRVIARAEKMEAMEQERIGRLVDRLETMRKNVAGDGVNRCILCGEQLGMLGSACVVCEDCKKNVCTKCGVETSNNRPHPVWLCKICLEQREVWKRSGAWFFKGFPKQVLPQPMPIKKTKPQQPAGEPATQEQPTPESRHPARAPARGDMEDRRAPGQKPGPDLTSAPGRGSHGPPTRRASEARMSTTTRDSEGWDHGHGGGAGDTSRSPGGEQGLRRANSVQASRPAPASMPSPAPPQPVQPEAPPSDPGYPGAVAPAREERTGPTGGFQAAPHTAGPYSQAAPARQPPPAEEEEEEANSYDSDEATTLGALEFSLLYDQDNSNLQCTIIRAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPVWNETLQYHGITEEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKLKANQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERIGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKKIERWHQLQNENHVSSD

Target ORF information:

RefSeq Version	XM_006249381.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus rabphilin 3A (Rph3a), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006249381.3

ORF Insert Sequence:

ATGACTGACA CTGTGGTGAA CCGTTGGATG TACCCTGGTG ATGGCCCACT GCAGTCAAAT 
GACAAGGAAC AGCTGCAGGC AGGATGGTCC GTCCATCCTG GAGCACAGAC GGACAGGCAG 
AGGAAGCAGG AAGAACTGAC AGACGAGGAG AAGGAGATAA TCAACCGGGT GATAGCTCGG 
GCAGAGAAGA TGGAAGCCAT GGAGCAGGAG CGCATCGGGC GCCTGGTGGA CCGTCTGGAG 
ACCATGAGGA AGAATGTAGC TGGAGATGGT GTGAACCGTT GCATCCTGTG CGGGGAACAG 
CTGGGCATGC TGGGCTCTGC GTGTGTCGTG TGTGAAGACT GTAAGAAGAA TGTCTGCACC 
AAGTGTGGGG TGGAGACCTC CAACAACCGT CCGCATCCAG TATGGCTCTG TAAGATCTGC 
CTTGAGCAGA GAGAGGTCTG GAAGCGCTCG GGAGCATGGT TCTTCAAGGG TTTCCCAAAA 
CAGGTCCTTC CACAGCCCAT GCCTATAAAG AAGACCAAGC CCCAGCAGCC TGCTGGTGAG 
CCGGCCACCC AGGAGCAGCC TACACCCGAG TCCAGGCATC CAGCCAGAGC TCCAGCTCGA 
GGTGACATGG AGGACAGGAG GGCCCCAGGA CAGAAGCCAG GCCCTGACCT CACCTCTGCT 
CCTGGACGAG GAAGCCATGG GCCTCCCACA CGCAGGGCCT CTGAGGCCCG GATGAGTACA 
ACCACCCGTG ATTCTGAGGG CTGGGACCAT GGTCATGGTG GGGGTGCTGG AGACACCAGC 
CGGAGCCCAG GAGGTGAGCA AGGTTTGAGG CGAGCTAACT CAGTCCAGGC CTCCCGCCCA 
GCTCCAGCCT CCATGCCAAG CCCGGCACCT CCTCAGCCCG TGCAGCCAGA GGCTCCTCCA 
AGTGACCCTG GCTATCCAGG GGCTGTTGCC CCAGCCCGGG AGGAGAGGAC AGGACCCACA 
GGGGGCTTCC AGGCAGCGCC CCACACTGCG GGTCCCTATT CCCAGGCGGC CCCTGCCCGC 
CAGCCACCGC CTGCTGAGGA AGAGGAGGAA GAAGCCAACA GCTATGACTC AGATGAAGCA 
ACCACACTGG GTGCCCTGGA ATTCAGCCTT CTCTATGACC AAGACAACAG CAACCTGCAG 
TGCACCATCA TCAGGGCGAA GGGACTGAAG CCCATGGACT CCAACGGCTT AGCGGATCCC 
TATGTGAAGC TGCATCTGCT GCCTGGAGCC AGCAAGTCCA ACAAGCTTCG TACAAAGACC 
CTGCGCAACA CCCGGAACCC TGTGTGGAAC GAGACGCTGC AGTATCATGG CATTACTGAG 
GAGGACATGC AGAGGAAGAC ACTCAGGATC TCCGTATGTG ACGAGGACAA GTTTGGCCAC 
AATGAGTTCA TTGGTGAGAC CAGGTTCTCG CTCAAGAAAC TGAAGGCGAA CCAGAGGAAA 
AACTTCAACA TCTGCCTGGA GCGGGTGATC CCGATGAAGC GCGCAGGAAC CACTGGGTCA 
GCACGTGGCA TGGCTCTCTA TGAGGAGGAG CAGGTGGAGC GGATCGGAGA CATAGAGGAA 
CGGGGCAAGA TCCTGGTGTC CCTCATGTAC AGCACGCAGC AGGGCGGCCT CATCGTGGGA 
ATTATCCGCT GTGTGCACCT GGCTGCCATG GACGCCAACG GCTACTCAGA CCCCTTCGTC 
AAGCTCTGGC TGAAACCGGA CATGGGGAAG AAAGCCAAGC ACAAGACTCA GATTAAAAAG 
AAGACCCTGA ATCCCGAGTT TAATGAGGAG TTCTTTTATG ATATCAAACA CAGCGACCTG 
GCCAAAAAGT CCCTGGATAT CTCAGTGTGG GACTACGACA TTGGCAAATC GAATGATTAC 
ATCGGAGGCT GCCAGCTGGG GATCTCGGCC AAGGGCGAGC GCTTGAAACA TTGGTATGAG 
TGTCTGAAGA ACAAAGACAA GAAGATTGAA CGTTGGCACC AACTGCAGAA CGAGAACCAC 
GTGTCGAGCG ACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Rph3a ( NM_133518.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_598202.1 Rattus norvegicus rabphilin 3A (Rph3a), mRNA.

Price & Availability↑

CloneID	ORa00806
Clone ID Related Accession (Same CDS sequence)	NM_133518.1
Accession Version	NM_133518.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2055bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Rattus norvegicus(Norway rat)
Product	rabphilin-3A
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from U12571.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U12571.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGACTGACA CTGTGGTGAA CCGTTGGATG TACCCTGGTG ATGGCCCACT GCAGTCAAAT 
GACAAGGAAC AGCTGCAGGC AGGATGGTCC GTCCATCCTG GAGCACAGAC GGACAGGCAG 
AGGAAGCAGG AAGAACTGAC AGACGAGGAG AAGGAGATAA TCAACCGGGT GATAGCTCGG 
GCAGAGAAGA TGGAAACCAT GGAGCAGGAG CGCATCGGGC GCCTGGTGGA CCGTCTGGAG 
ACCATGAGGA AGAATGTAGC TGGAGATGGT GTGAACCGTT GCATCCTGTG CGGGGAACAG 
CTGGGCATGC TGGGCTCTGC GTGTGTCGTG TGTGAAGACT GTAAGAAGAA TGTCTGCACC 
AAGTGTGGGG TGGAGACCTC CAACAACCGT CCGCATCCAG TATGGCTCTG TAAGATCTGC 
CTTGAGCAGA GAGAGGTCTG GAAGCGCTCG GGAGCATGGT TCTTCAAGGG TTTCCCAAAA 
CAGGTCCTTC CACAGCCCAT GCCTATAAAG AAGACCAAGC CCCAGCAGCC TGCTGGTGAG 
CCGGCCACCC AGGAGCAGCC TACACCCGAG TCCAGGCATC CAGCCAGAGC TCCAGCTCGA 
GGTGACATGG AGGACAGGAG GGCCCCAGGA CAGAAGCCAG GCCCTGACCT CACCTCTGCT 
CCTGGACGAG GAAGCCATGG GCCTCCCACA CGCAGGGCCT CTGAGGCCCG GATGAGTACA 
ACCACCCGTG ATTCTGAGGG CTGGGACCAT GGTCATGGTG GGGGTGCTGG AGACACCAGC 
CGGAGCCCAG GAGGTGAGCA AGGTTTGAGG CGAGCTAACT CAGTCCAGGC CTCCCGCCCA 
GCTCCAGCCT CCATGCCAAG CCCGGCACCT CCTCAGCCCG TGCAGCCAGG GCCCCCTGGG 
GGCAGCAGGG CCGCTCCTGG GCCGGGACGC TTTCCAGAGC AGAGCACAGA GGCTCCTCCA 
AGTGACCCTG GCTATCCAGG GGCTGTTGCC CCAGCCCGGG AGGAGAGGAC AGGACCCACA 
GGGGGCTTCC AGGCAGCGCC CCACACTGCG GGTCCCTATT CCCAGGCGGC CCCTGCCCGC 
CAGCCACCGC CTGCTGAGGA AGAGGAGGAA GAAGCCAACA GCTATGACTC AGATCAAGCA 
ACCACACTGG GTGCCCTGGA ATTCAGCCTT CTCTATGACC AAGACAACAG CAACCTGCAG 
TGCACCATCA TCAGGGCGAA GGGACTGAAG CCCATGGACT CCAACGGCTT AGCGGATCCC 
TATGTGAAGC TGCATCTGCT GCCTGGAGCC AGCAAGTCCA ACAAGCTTCG TACAAAGACC 
CTGCGCAACA CCCGGAACCC TGTGTGGAAC GAGACGCTGC AGTATCATGG CATTACTGAG 
GAGGACATGC AGAGGAAGAC ACTCAGGATC TCTGTATGTG ACGAGGACAA GTTTGGCCAC 
AATGAGTTCA TTGGTGAGAC CAGGTTCTCG CTCAAGAAAC TGAAGGCGAA CCAGAGGAAA 
AACTTCAACA TCTGCCTGGA GCGGGTGATC CCGATGAAGC GCGCAGGAAC CACTGGGTCA 
GCACGTGGCA TGGCTCTCTA TGAGGAGGAG CAGGTGGAGC GGATCGGAGA CATAGAGGAA 
CGGGGCAAGA TCCTGGTGTC CCTCATGTAC AGCACGCAGC AGGGCGGCCT CATCGTGGGA 
ATTATCCGCT GTGTGCACCT GGCTGCCATG GACGCCAACG GCTACTCAGA CCCCTTCGTC 
AAGCTCTGGC TGAAACCGGA CATGGGGAAG AAAGCCAAGC ACAAGACTCA GATTAAAAAG 
AAGACCCTGA ATCCCGAGTT TAATGAGGAG TTCTTTTATG ATATCAAACA CAGCGACCTG 
GCCAAAAAGT CCCTGGATAT CTCAGTGTGG GACTACGACA TTGGCAAATC GAATGATTAC 
ATCGGAGGCT GCCAGCTGGG GATCTCGGCC AAGGGCGAGC GCTTGAAACA TTGGTATGAG 
TGTCTGAAGA ACAAAGACAA GAAGATTGAA CGTTGGCACC AACTGCAGAA CGAGAACCAC 
GTGTCGAGCG ACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_598202.1
CDS	283..2337
Translation	MTDTVVNRWMYPGDGPLQSNDKEQLQAGWSVHPGAQTDRQRKQEELTDEEKEIINRVIARAEKMETMEQERIGRLVDRLETMRKNVAGDGVNRCILCGEQLGMLGSACVVCEDCKKNVCTKCGVETSNNRPHPVWLCKICLEQREVWKRSGAWFFKGFPKQVLPQPMPIKKTKPQQPAGEPATQEQPTPESRHPARAPARGDMEDRRAPGQKPGPDLTSAPGRGSHGPPTRRASEARMSTTTRDSEGWDHGHGGGAGDTSRSPGGEQGLRRANSVQASRPAPASMPSPAPPQPVQPGPPGGSRAAPGPGRFPEQSTEAPPSDPGYPGAVAPAREERTGPTGGFQAAPHTAGPYSQAAPARQPPPAEEEEEEANSYDSDQATTLGALEFSLLYDQDNSNLQCTIIRAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPVWNETLQYHGITEEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKLKANQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERIGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKKIERWHQLQNENHVSSD

Target ORF information:

RefSeq Version	NM_133518.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus rabphilin 3A (Rph3a), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_133518.1

ORF Insert Sequence:

ATGACTGACA CTGTGGTGAA CCGTTGGATG TACCCTGGTG ATGGCCCACT GCAGTCAAAT 
GACAAGGAAC AGCTGCAGGC AGGATGGTCC GTCCATCCTG GAGCACAGAC GGACAGGCAG 
AGGAAGCAGG AAGAACTGAC AGACGAGGAG AAGGAGATAA TCAACCGGGT GATAGCTCGG 
GCAGAGAAGA TGGAAACCAT GGAGCAGGAG CGCATCGGGC GCCTGGTGGA CCGTCTGGAG 
ACCATGAGGA AGAATGTAGC TGGAGATGGT GTGAACCGTT GCATCCTGTG CGGGGAACAG 
CTGGGCATGC TGGGCTCTGC GTGTGTCGTG TGTGAAGACT GTAAGAAGAA TGTCTGCACC 
AAGTGTGGGG TGGAGACCTC CAACAACCGT CCGCATCCAG TATGGCTCTG TAAGATCTGC 
CTTGAGCAGA GAGAGGTCTG GAAGCGCTCG GGAGCATGGT TCTTCAAGGG TTTCCCAAAA 
CAGGTCCTTC CACAGCCCAT GCCTATAAAG AAGACCAAGC CCCAGCAGCC TGCTGGTGAG 
CCGGCCACCC AGGAGCAGCC TACACCCGAG TCCAGGCATC CAGCCAGAGC TCCAGCTCGA 
GGTGACATGG AGGACAGGAG GGCCCCAGGA CAGAAGCCAG GCCCTGACCT CACCTCTGCT 
CCTGGACGAG GAAGCCATGG GCCTCCCACA CGCAGGGCCT CTGAGGCCCG GATGAGTACA 
ACCACCCGTG ATTCTGAGGG CTGGGACCAT GGTCATGGTG GGGGTGCTGG AGACACCAGC 
CGGAGCCCAG GAGGTGAGCA AGGTTTGAGG CGAGCTAACT CAGTCCAGGC CTCCCGCCCA 
GCTCCAGCCT CCATGCCAAG CCCGGCACCT CCTCAGCCCG TGCAGCCAGG GCCCCCTGGG 
GGCAGCAGGG CCGCTCCTGG GCCGGGACGC TTTCCAGAGC AGAGCACAGA GGCTCCTCCA 
AGTGACCCTG GCTATCCAGG GGCTGTTGCC CCAGCCCGGG AGGAGAGGAC AGGACCCACA 
GGGGGCTTCC AGGCAGCGCC CCACACTGCG GGTCCCTATT CCCAGGCGGC CCCTGCCCGC 
CAGCCACCGC CTGCTGAGGA AGAGGAGGAA GAAGCCAACA GCTATGACTC AGATCAAGCA 
ACCACACTGG GTGCCCTGGA ATTCAGCCTT CTCTATGACC AAGACAACAG CAACCTGCAG 
TGCACCATCA TCAGGGCGAA GGGACTGAAG CCCATGGACT CCAACGGCTT AGCGGATCCC 
TATGTGAAGC TGCATCTGCT GCCTGGAGCC AGCAAGTCCA ACAAGCTTCG TACAAAGACC 
CTGCGCAACA CCCGGAACCC TGTGTGGAAC GAGACGCTGC AGTATCATGG CATTACTGAG 
GAGGACATGC AGAGGAAGAC ACTCAGGATC TCTGTATGTG ACGAGGACAA GTTTGGCCAC 
AATGAGTTCA TTGGTGAGAC CAGGTTCTCG CTCAAGAAAC TGAAGGCGAA CCAGAGGAAA 
AACTTCAACA TCTGCCTGGA GCGGGTGATC CCGATGAAGC GCGCAGGAAC CACTGGGTCA 
GCACGTGGCA TGGCTCTCTA TGAGGAGGAG CAGGTGGAGC GGATCGGAGA CATAGAGGAA 
CGGGGCAAGA TCCTGGTGTC CCTCATGTAC AGCACGCAGC AGGGCGGCCT CATCGTGGGA 
ATTATCCGCT GTGTGCACCT GGCTGCCATG GACGCCAACG GCTACTCAGA CCCCTTCGTC 
AAGCTCTGGC TGAAACCGGA CATGGGGAAG AAAGCCAAGC ACAAGACTCA GATTAAAAAG 
AAGACCCTGA ATCCCGAGTT TAATGAGGAG TTCTTTTATG ATATCAAACA CAGCGACCTG 
GCCAAAAAGT CCCTGGATAT CTCAGTGTGG GACTACGACA TTGGCAAATC GAATGATTAC 
ATCGGAGGCT GCCAGCTGGG GATCTCGGCC AAGGGCGAGC GCTTGAAACA TTGGTATGAG 
TGTCTGAAGA ACAAAGACAA GAAGATTGAA CGTTGGCACC AACTGCAGAA CGAGAACCAC 
GTGTCGAGCG ACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Rph3a ( XM_006249379.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006249441.1 Rattus norvegicus rabphilin 3A (Rph3a), transcript variant X1, mRNA.

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CloneID	ORa35050
Clone ID Related Accession (Same CDS sequence)	XM_006249379.3
Accession Version	XM_006249379.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2055bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	rabphilin-3A isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005111.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006249379.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACTGACA CTGTGGTGAA CCGTTGGATG TACCCTGGTG ATGGCCCACT GCAGTCAAAT 
GACAAGGAAC AGCTGCAGGC AGGATGGTCC GTCCATCCTG GAGCACAGAC GGACAGGCAG 
AGGAAGCAGG AAGAACTGAC AGACGAGGAG AAGGAGATAA TCAACCGGGT GATAGCTCGG 
GCAGAGAAGA TGGAAGCCAT GGAGCAGGAG CGCATCGGGC GCCTGGTGGA CCGTCTGGAG 
ACCATGAGGA AGAATGTAGC TGGAGATGGT GTGAACCGTT GCATCCTGTG CGGGGAACAG 
CTGGGCATGC TGGGCTCTGC GTGTGTCGTG TGTGAAGACT GTAAGAAGAA TGTCTGCACC 
AAGTGTGGGG TGGAGACCTC CAACAACCGT CCGCATCCAG TATGGCTCTG TAAGATCTGC 
CTTGAGCAGA GAGAGGTCTG GAAGCGCTCG GGAGCATGGT TCTTCAAGGG TTTCCCAAAA 
CAGGTCCTTC CACAGCCCAT GCCTATAAAG AAGACCAAGC CCCAGCAGCC TGCTGGTGAG 
CCGGCCACCC AGGAGCAGCC TACACCCGAG TCCAGGCATC CAGCCAGAGC TCCAGCTCGA 
GGTGACATGG AGGACAGGAG GGCCCCAGGA CAGAAGCCAG GCCCTGACCT CACCTCTGCT 
CCTGGACGAG GAAGCCATGG GCCTCCCACA CGCAGGGCCT CTGAGGCCCG GATGAGTACA 
ACCACCCGTG ATTCTGAGGG CTGGGACCAT GGTCATGGTG GGGGTGCTGG AGACACCAGC 
CGGAGCCCAG GAGGTGAGCA AGGTTTGAGG CGAGCTAACT CAGTCCAGGC CTCCCGCCCA 
GCTCCAGCCT CCATGCCAAG CCCGGCACCT CCTCAGCCCG TGCAGCCAGG GCCCCCTGGG 
GGCAGCAGGG CCGCTCCTGG GCCGGGACGC TTTCCAGAGC AGAGCACAGA GGCTCCTCCA 
AGTGACCCTG GCTATCCAGG GGCTGTTGCC CCAGCCCGGG AGGAGAGGAC AGGACCCACA 
GGGGGCTTCC AGGCAGCGCC CCACACTGCG GGTCCCTATT CCCAGGCGGC CCCTGCCCGC 
CAGCCACCGC CTGCTGAGGA AGAGGAGGAA GAAGCCAACA GCTATGACTC AGATGAAGCA 
ACCACACTGG GTGCCCTGGA ATTCAGCCTT CTCTATGACC AAGACAACAG CAACCTGCAG 
TGCACCATCA TCAGGGCGAA GGGACTGAAG CCCATGGACT CCAACGGCTT AGCGGATCCC 
TATGTGAAGC TGCATCTGCT GCCTGGAGCC AGCAAGTCCA ACAAGCTTCG TACAAAGACC 
CTGCGCAACA CCCGGAACCC TGTGTGGAAC GAGACGCTGC AGTATCATGG CATTACTGAG 
GAGGACATGC AGAGGAAGAC ACTCAGGATC TCCGTATGTG ACGAGGACAA GTTTGGCCAC 
AATGAGTTCA TTGGTGAGAC CAGGTTCTCG CTCAAGAAAC TGAAGGCGAA CCAGAGGAAA 
AACTTCAACA TCTGCCTGGA GCGGGTGATC CCGATGAAGC GCGCAGGAAC CACTGGGTCA 
GCACGTGGCA TGGCTCTCTA TGAGGAGGAG CAGGTGGAGC GGATCGGAGA CATAGAGGAA 
CGGGGCAAGA TCCTGGTGTC CCTCATGTAC AGCACGCAGC AGGGCGGCCT CATCGTGGGA 
ATTATCCGCT GTGTGCACCT GGCTGCCATG GACGCCAACG GCTACTCAGA CCCCTTCGTC 
AAGCTCTGGC TGAAACCGGA CATGGGGAAG AAAGCCAAGC ACAAGACTCA GATTAAAAAG 
AAGACCCTGA ATCCCGAGTT TAATGAGGAG TTCTTTTATG ATATCAAACA CAGCGACCTG 
GCCAAAAAGT CCCTGGATAT CTCAGTGTGG GACTACGACA TTGGCAAATC GAATGATTAC 
ATCGGAGGCT GCCAGCTGGG GATCTCGGCC AAGGGCGAGC GCTTGAAACA TTGGTATGAG 
TGTCTGAAGA ACAAAGACAA GAAGATTGAA CGTTGGCACC AACTGCAGAA CGAGAACCAC 
GTGTCGAGCG ACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006249441.1
CDS	213..2267
Translation	MTDTVVNRWMYPGDGPLQSNDKEQLQAGWSVHPGAQTDRQRKQEELTDEEKEIINRVIARAEKMEAMEQERIGRLVDRLETMRKNVAGDGVNRCILCGEQLGMLGSACVVCEDCKKNVCTKCGVETSNNRPHPVWLCKICLEQREVWKRSGAWFFKGFPKQVLPQPMPIKKTKPQQPAGEPATQEQPTPESRHPARAPARGDMEDRRAPGQKPGPDLTSAPGRGSHGPPTRRASEARMSTTTRDSEGWDHGHGGGAGDTSRSPGGEQGLRRANSVQASRPAPASMPSPAPPQPVQPGPPGGSRAAPGPGRFPEQSTEAPPSDPGYPGAVAPAREERTGPTGGFQAAPHTAGPYSQAAPARQPPPAEEEEEEANSYDSDEATTLGALEFSLLYDQDNSNLQCTIIRAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPVWNETLQYHGITEEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKLKANQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERIGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKKIERWHQLQNENHVSSD

Target ORF information:

RefSeq Version	XM_006249379.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus rabphilin 3A (Rph3a), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006249379.3

ORF Insert Sequence:

ATGACTGACA CTGTGGTGAA CCGTTGGATG TACCCTGGTG ATGGCCCACT GCAGTCAAAT 
GACAAGGAAC AGCTGCAGGC AGGATGGTCC GTCCATCCTG GAGCACAGAC GGACAGGCAG 
AGGAAGCAGG AAGAACTGAC AGACGAGGAG AAGGAGATAA TCAACCGGGT GATAGCTCGG 
GCAGAGAAGA TGGAAGCCAT GGAGCAGGAG CGCATCGGGC GCCTGGTGGA CCGTCTGGAG 
ACCATGAGGA AGAATGTAGC TGGAGATGGT GTGAACCGTT GCATCCTGTG CGGGGAACAG 
CTGGGCATGC TGGGCTCTGC GTGTGTCGTG TGTGAAGACT GTAAGAAGAA TGTCTGCACC 
AAGTGTGGGG TGGAGACCTC CAACAACCGT CCGCATCCAG TATGGCTCTG TAAGATCTGC 
CTTGAGCAGA GAGAGGTCTG GAAGCGCTCG GGAGCATGGT TCTTCAAGGG TTTCCCAAAA 
CAGGTCCTTC CACAGCCCAT GCCTATAAAG AAGACCAAGC CCCAGCAGCC TGCTGGTGAG 
CCGGCCACCC AGGAGCAGCC TACACCCGAG TCCAGGCATC CAGCCAGAGC TCCAGCTCGA 
GGTGACATGG AGGACAGGAG GGCCCCAGGA CAGAAGCCAG GCCCTGACCT CACCTCTGCT 
CCTGGACGAG GAAGCCATGG GCCTCCCACA CGCAGGGCCT CTGAGGCCCG GATGAGTACA 
ACCACCCGTG ATTCTGAGGG CTGGGACCAT GGTCATGGTG GGGGTGCTGG AGACACCAGC 
CGGAGCCCAG GAGGTGAGCA AGGTTTGAGG CGAGCTAACT CAGTCCAGGC CTCCCGCCCA 
GCTCCAGCCT CCATGCCAAG CCCGGCACCT CCTCAGCCCG TGCAGCCAGG GCCCCCTGGG 
GGCAGCAGGG CCGCTCCTGG GCCGGGACGC TTTCCAGAGC AGAGCACAGA GGCTCCTCCA 
AGTGACCCTG GCTATCCAGG GGCTGTTGCC CCAGCCCGGG AGGAGAGGAC AGGACCCACA 
GGGGGCTTCC AGGCAGCGCC CCACACTGCG GGTCCCTATT CCCAGGCGGC CCCTGCCCGC 
CAGCCACCGC CTGCTGAGGA AGAGGAGGAA GAAGCCAACA GCTATGACTC AGATGAAGCA 
ACCACACTGG GTGCCCTGGA ATTCAGCCTT CTCTATGACC AAGACAACAG CAACCTGCAG 
TGCACCATCA TCAGGGCGAA GGGACTGAAG CCCATGGACT CCAACGGCTT AGCGGATCCC 
TATGTGAAGC TGCATCTGCT GCCTGGAGCC AGCAAGTCCA ACAAGCTTCG TACAAAGACC 
CTGCGCAACA CCCGGAACCC TGTGTGGAAC GAGACGCTGC AGTATCATGG CATTACTGAG 
GAGGACATGC AGAGGAAGAC ACTCAGGATC TCCGTATGTG ACGAGGACAA GTTTGGCCAC 
AATGAGTTCA TTGGTGAGAC CAGGTTCTCG CTCAAGAAAC TGAAGGCGAA CCAGAGGAAA 
AACTTCAACA TCTGCCTGGA GCGGGTGATC CCGATGAAGC GCGCAGGAAC CACTGGGTCA 
GCACGTGGCA TGGCTCTCTA TGAGGAGGAG CAGGTGGAGC GGATCGGAGA CATAGAGGAA 
CGGGGCAAGA TCCTGGTGTC CCTCATGTAC AGCACGCAGC AGGGCGGCCT CATCGTGGGA 
ATTATCCGCT GTGTGCACCT GGCTGCCATG GACGCCAACG GCTACTCAGA CCCCTTCGTC 
AAGCTCTGGC TGAAACCGGA CATGGGGAAG AAAGCCAAGC ACAAGACTCA GATTAAAAAG 
AAGACCCTGA ATCCCGAGTT TAATGAGGAG TTCTTTTATG ATATCAAACA CAGCGACCTG 
GCCAAAAAGT CCCTGGATAT CTCAGTGTGG GACTACGACA TTGGCAAATC GAATGATTAC 
ATCGGAGGCT GCCAGCTGGG GATCTCGGCC AAGGGCGAGC GCTTGAAACA TTGGTATGAG 
TGTCTGAAGA ACAAAGACAA GAAGATTGAA CGTTGGCACC AACTGCAGAA CGAGAACCAC 
GTGTCGAGCG ACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Rph3a ( XM_006249380.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006249442.1 Rattus norvegicus rabphilin 3A (Rph3a), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa35051
Clone ID Related Accession (Same CDS sequence)	XM_006249380.3
Accession Version	XM_006249380.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2046bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	rabphilin-3A isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005111.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006249380.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACTGACA CTGTGGTGAA CCGTTGGATG TACCCTGGTG ATGGCCCACT GCAGTCAAAT 
GACAAGGAAC AGCTGCAGGC AGGATGGTCC GTCCATCCTG GAGCACAGAC GGACAGGCAG 
AGGAAGCAGG AAGAACTGAC AGACGAGGAG AAGGAGATAA TCAACCGGGT GATAGCTCGG 
GCAGAGAAGA TGGAAGCCAT GGAGCAGGAG CGCATCGGGC GCCTGGTGGA CCGTCTGGAG 
ACCATGAGGA AGAATGTAGC TGGAGATGGT GTGAACCGTT GCATCCTGTG CGGGGAACAG 
CTGGGCATGC TGGGCTCTGC GTGTGTCGTG TGTGAAGACT GTAAGAAGAA TGTCTGCACC 
AAGTGTGGGG TGGAGACCTC CAACAACCGT CCGCATCCAG TATGGCTCTG TAAGATCTGC 
CTTGAGCAGA GAGAGGTCTG GAAGCGCTCG GGAGCATGGT TCTTCAAGGG TTTCCCAAAA 
CAGGTCCTTC CACAGCCCAT GCCTATAAAG AAGACCAAGC CCCAGCAGCC TGCTGGTGAG 
CCGGCCACCC AGGAGCAGCC TACACCCGAG TCCAGGCATC CAGCCAGAGC TCCAGCTCGA 
GGTGACATGG AGGACAGGAG GGCCCCAGGA CAGAAGCCAG GCCCTGACCT CACCTCTGCT 
CCTGGACGAG GAAGCCATGG GCCTCCCACA CGCAGGGCCT CTGAGGCCCG GATGAGTACA 
ACCACCCGTG ATTCTGAGGG CTGGGACCAT GGTCATGGTG GGGGTGCTGG AGACACCAGC 
CGGAGCCCAG GAGGTTTGAG GCGAGCTAAC TCAGTCCAGG CCTCCCGCCC AGCTCCAGCC 
TCCATGCCAA GCCCGGCACC TCCTCAGCCC GTGCAGCCAG GGCCCCCTGG GGGCAGCAGG 
GCCGCTCCTG GGCCGGGACG CTTTCCAGAG CAGAGCACAG AGGCTCCTCC AAGTGACCCT 
GGCTATCCAG GGGCTGTTGC CCCAGCCCGG GAGGAGAGGA CAGGACCCAC AGGGGGCTTC 
CAGGCAGCGC CCCACACTGC GGGTCCCTAT TCCCAGGCGG CCCCTGCCCG CCAGCCACCG 
CCTGCTGAGG AAGAGGAGGA AGAAGCCAAC AGCTATGACT CAGATGAAGC AACCACACTG 
GGTGCCCTGG AATTCAGCCT TCTCTATGAC CAAGACAACA GCAACCTGCA GTGCACCATC 
ATCAGGGCGA AGGGACTGAA GCCCATGGAC TCCAACGGCT TAGCGGATCC CTATGTGAAG 
CTGCATCTGC TGCCTGGAGC CAGCAAGTCC AACAAGCTTC GTACAAAGAC CCTGCGCAAC 
ACCCGGAACC CTGTGTGGAA CGAGACGCTG CAGTATCATG GCATTACTGA GGAGGACATG 
CAGAGGAAGA CACTCAGGAT CTCCGTATGT GACGAGGACA AGTTTGGCCA CAATGAGTTC 
ATTGGTGAGA CCAGGTTCTC GCTCAAGAAA CTGAAGGCGA ACCAGAGGAA AAACTTCAAC 
ATCTGCCTGG AGCGGGTGAT CCCGATGAAG CGCGCAGGAA CCACTGGGTC AGCACGTGGC 
ATGGCTCTCT ATGAGGAGGA GCAGGTGGAG CGGATCGGAG ACATAGAGGA ACGGGGCAAG 
ATCCTGGTGT CCCTCATGTA CAGCACGCAG CAGGGCGGCC TCATCGTGGG AATTATCCGC 
TGTGTGCACC TGGCTGCCAT GGACGCCAAC GGCTACTCAG ACCCCTTCGT CAAGCTCTGG 
CTGAAACCGG ACATGGGGAA GAAAGCCAAG CACAAGACTC AGATTAAAAA GAAGACCCTG 
AATCCCGAGT TTAATGAGGA GTTCTTTTAT GATATCAAAC ACAGCGACCT GGCCAAAAAG 
TCCCTGGATA TCTCAGTGTG GGACTACGAC ATTGGCAAAT CGAATGATTA CATCGGAGGC 
TGCCAGCTGG GGATCTCGGC CAAGGGCGAG CGCTTGAAAC ATTGGTATGA GTGTCTGAAG 
AACAAAGACA AGAAGATTGA ACGTTGGCAC CAACTGCAGA ACGAGAACCA CGTGTCGAGC 
GACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006249442.1
CDS	554..2599
Translation	MTDTVVNRWMYPGDGPLQSNDKEQLQAGWSVHPGAQTDRQRKQEELTDEEKEIINRVIARAEKMEAMEQERIGRLVDRLETMRKNVAGDGVNRCILCGEQLGMLGSACVVCEDCKKNVCTKCGVETSNNRPHPVWLCKICLEQREVWKRSGAWFFKGFPKQVLPQPMPIKKTKPQQPAGEPATQEQPTPESRHPARAPARGDMEDRRAPGQKPGPDLTSAPGRGSHGPPTRRASEARMSTTTRDSEGWDHGHGGGAGDTSRSPGGLRRANSVQASRPAPASMPSPAPPQPVQPGPPGGSRAAPGPGRFPEQSTEAPPSDPGYPGAVAPAREERTGPTGGFQAAPHTAGPYSQAAPARQPPPAEEEEEEANSYDSDEATTLGALEFSLLYDQDNSNLQCTIIRAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPVWNETLQYHGITEEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKLKANQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERIGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKKIERWHQLQNENHVSSD

Target ORF information:

RefSeq Version	XM_006249380.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus rabphilin 3A (Rph3a), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006249380.3

ORF Insert Sequence:

ATGACTGACA CTGTGGTGAA CCGTTGGATG TACCCTGGTG ATGGCCCACT GCAGTCAAAT 
GACAAGGAAC AGCTGCAGGC AGGATGGTCC GTCCATCCTG GAGCACAGAC GGACAGGCAG 
AGGAAGCAGG AAGAACTGAC AGACGAGGAG AAGGAGATAA TCAACCGGGT GATAGCTCGG 
GCAGAGAAGA TGGAAGCCAT GGAGCAGGAG CGCATCGGGC GCCTGGTGGA CCGTCTGGAG 
ACCATGAGGA AGAATGTAGC TGGAGATGGT GTGAACCGTT GCATCCTGTG CGGGGAACAG 
CTGGGCATGC TGGGCTCTGC GTGTGTCGTG TGTGAAGACT GTAAGAAGAA TGTCTGCACC 
AAGTGTGGGG TGGAGACCTC CAACAACCGT CCGCATCCAG TATGGCTCTG TAAGATCTGC 
CTTGAGCAGA GAGAGGTCTG GAAGCGCTCG GGAGCATGGT TCTTCAAGGG TTTCCCAAAA 
CAGGTCCTTC CACAGCCCAT GCCTATAAAG AAGACCAAGC CCCAGCAGCC TGCTGGTGAG 
CCGGCCACCC AGGAGCAGCC TACACCCGAG TCCAGGCATC CAGCCAGAGC TCCAGCTCGA 
GGTGACATGG AGGACAGGAG GGCCCCAGGA CAGAAGCCAG GCCCTGACCT CACCTCTGCT 
CCTGGACGAG GAAGCCATGG GCCTCCCACA CGCAGGGCCT CTGAGGCCCG GATGAGTACA 
ACCACCCGTG ATTCTGAGGG CTGGGACCAT GGTCATGGTG GGGGTGCTGG AGACACCAGC 
CGGAGCCCAG GAGGTTTGAG GCGAGCTAAC TCAGTCCAGG CCTCCCGCCC AGCTCCAGCC 
TCCATGCCAA GCCCGGCACC TCCTCAGCCC GTGCAGCCAG GGCCCCCTGG GGGCAGCAGG 
GCCGCTCCTG GGCCGGGACG CTTTCCAGAG CAGAGCACAG AGGCTCCTCC AAGTGACCCT 
GGCTATCCAG GGGCTGTTGC CCCAGCCCGG GAGGAGAGGA CAGGACCCAC AGGGGGCTTC 
CAGGCAGCGC CCCACACTGC GGGTCCCTAT TCCCAGGCGG CCCCTGCCCG CCAGCCACCG 
CCTGCTGAGG AAGAGGAGGA AGAAGCCAAC AGCTATGACT CAGATGAAGC AACCACACTG 
GGTGCCCTGG AATTCAGCCT TCTCTATGAC CAAGACAACA GCAACCTGCA GTGCACCATC 
ATCAGGGCGA AGGGACTGAA GCCCATGGAC TCCAACGGCT TAGCGGATCC CTATGTGAAG 
CTGCATCTGC TGCCTGGAGC CAGCAAGTCC AACAAGCTTC GTACAAAGAC CCTGCGCAAC 
ACCCGGAACC CTGTGTGGAA CGAGACGCTG CAGTATCATG GCATTACTGA GGAGGACATG 
CAGAGGAAGA CACTCAGGAT CTCCGTATGT GACGAGGACA AGTTTGGCCA CAATGAGTTC 
ATTGGTGAGA CCAGGTTCTC GCTCAAGAAA CTGAAGGCGA ACCAGAGGAA AAACTTCAAC 
ATCTGCCTGG AGCGGGTGAT CCCGATGAAG CGCGCAGGAA CCACTGGGTC AGCACGTGGC 
ATGGCTCTCT ATGAGGAGGA GCAGGTGGAG CGGATCGGAG ACATAGAGGA ACGGGGCAAG 
ATCCTGGTGT CCCTCATGTA CAGCACGCAG CAGGGCGGCC TCATCGTGGG AATTATCCGC 
TGTGTGCACC TGGCTGCCAT GGACGCCAAC GGCTACTCAG ACCCCTTCGT CAAGCTCTGG 
CTGAAACCGG ACATGGGGAA GAAAGCCAAG CACAAGACTC AGATTAAAAA GAAGACCCTG 
AATCCCGAGT TTAATGAGGA GTTCTTTTAT GATATCAAAC ACAGCGACCT GGCCAAAAAG 
TCCCTGGATA TCTCAGTGTG GGACTACGAC ATTGGCAAAT CGAATGATTA CATCGGAGGC 
TGCCAGCTGG GGATCTCGGC CAAGGGCGAG CGCTTGAAAC ATTGGTATGA GTGTCTGAAG 
AACAAAGACA AGAAGATTGA ACGTTGGCAC CAACTGCAGA ACGAGAACCA CGTGTCGAGC 
GACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Rabphilin 3A: A novel target for the treatment of levodopa-induced dyskinesias.
Neurobiology of disease10854-64(2017 Dec)
Stanic J,Mellone M,Napolitano F,Racca C,Zianni E,Minocci D,Ghiglieri V,Thiolat ML,Li Q,Longhi A,De Rosa A,Picconi B,Bezard E,Calabresi P,Di Luca M,Usiello A,Gardoni F

Rabphilin 3A retains NMDA receptors at synaptic sites through interaction with GluN2A/PSD-95 complex.
Nature communications610181(2015 Dec)
Stanic J,Carta M,Eberini I,Pelucchi S,Marcello E,Genazzani AA,Racca C,Mulle C,Di Luca M,Gardoni F

Doc2 supports spontaneous synaptic transmission by a Ca(2+)-independent mechanism.
Neuron70(2)244-51(2011 Apr)
Pang ZP,Bacaj T,Yang X,Zhou P,Xu W,S?dhof TC

In-depth fluorescence lifetime imaging analysis revealing SNAP25A-Rabphilin 3A interactions.
Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada14(6)507-18(2008 Dec)
Lee JD,Huang PC,Lin YC,Kao LS,Huang CC,Kao FJ,Lin CC,Yang DM

Structural determinants for Ca2+ and phosphatidylinositol 4,5-bisphosphate binding by the C2A domain of rabphilin-3A.
The Journal of biological chemistry283(51)35918-28(2008 Dec)
Coudevylle N,Montaville P,Leonov A,Zweckstetter M,Becker S

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Rph3a cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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