Abcc4 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Abcc4
Entrez Gene ID	170924
Full Name	ATP binding cassette subfamily C member 4
Synonyms	Mrp4,RGD1565953
General protein information	Preferred Names ATP binding cassette subfamily C member 4 Names multidrug resistance-associated protein 4 ABC-tranporter ATP-binding cassette protein C4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 ATP-binding cassette, subfamily C (CFTR/MRP), member 4
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 15 Map Location: 15q24
Summary	ATP-binding cassette (ABC) multiple drug resistance protein (MRP) that mediates reduced glutatione release from hepatocytes into blood by cotransport with monoanionic bile salts [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_008770939.1	XP_008769161.1	multidrug resistance-associated protein 4 isoform X1
NM_133411.1	NP_596902.1	multidrug resistance-associated protein 4

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Abcc4	NP_001028508.2
Rattus norvegicus (Norway rat)	Abcc4	NP_596902.1
Gallus gallus (chicken)	ABCC4	NP_001025990.1
Drosophila melanogaster (fruit fly)	l(2)03659	NP_001260823.1
Arabidopsis thaliana (thale cress)	MRP8	NP_187916.3
Arabidopsis thaliana (thale cress)	MRP7	NP_187917.3
Pan troglodytes (chimpanzee)	ABCC4	XP_001137006.1
Drosophila melanogaster (fruit fly)	CG7627	NP_609215.3
Drosophila melanogaster (fruit fly)	CG31793	NP_609930.4
Caenorhabditis elegans (roundworm)	mrp-6	NP_508710.3
Danio rerio (zebrafish)	abcc4	NP_001007039.1
Drosophila melanogaster (fruit fly)	CG31792	NP_001260548.1
Drosophila melanogaster (fruit fly)	CG4562	NP_001262747.1
Xenopus tropicalis (tropical clawed frog)	abcc4	XP_002939329.2
Homo sapiens (human)	ABCC4	NP_005836.2
Canis lupus familiaris (dog)	ABCC4	NP_001184103.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP006427	XP_316463.3
Arabidopsis thaliana (thale cress)	MRP3	NP_187915.1
Drosophila melanogaster (fruit fly)	Mrp4	NP_650086.2
Drosophila melanogaster (fruit fly)	CG9270	NP_995741.2
Oryza sativa (rice)	Os01g0173900	NP_001042159.1

Gene Ontology
Bibliography

Related articles in PubMed

Modulation of transport and metabolism of bile acids and bilirubin by chlorogenic acid against hepatotoxity and cholestasis in bile duct ligation rats: involvement of SIRT1-mediated deacetylation of FXR and PGC-1?.
Zhu L, Wang L, Cao F, Liu P, Bao H, Yan Y, Dong X, Wang D, Wang Z, Gong P
Journal of hepato-biliary-pancreatic sciences(2018 Jan)

Nrf2 signaling increases expression of ATP-binding cassette subfamily C mRNA transcripts at the blood-brain barrier following hypoxia-reoxygenation stress.
Ibbotson K, Yell J, Ronaldson PT
Fluids and barriers of the CNS14(1)6(2017 Mar)

Effect of Multi Drug Resistance Protein 4 (MRP4) Inhibition on the Pharmacokinetics and Pharmacodynamics of Ciprofloxacin in Normal and Rats with LPS-Induced Inflammation.
Prasad VG, Achanta S, Tammineni YR, Alla GR, Thirtham MR, Rao GS
European journal of drug metabolism and pharmacokinetics41(6)733-741(2016 Dec)

Identification and Functional Characterization of a GSH Conjugate Efflux Pathway in the Rat Lens.
Umapathy A, Li B, Donaldson PJ, Lim JC
Investigative ophthalmology & visual science56(9)5256-68(2015 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The data of this study show increased Abcc1, Abcc2, and Abcc4 mRNA expression at the BBB in response to H/R stress and that Abcc gene expression is regulated by Nrf2 signaling.
Title: Nrf2 signaling increases expression of ATP-binding cassette subfamily C mRNA transcripts at the blood-brain barrier following hypoxia-reoxygenation stress.

Multidrug resistance-associated proteins 1, 4, 5, and Oatp1a4 were present at the transcript level, but only Mrp1, 4, and 5 were detected at the protein level.
Title: Identification and Functional Characterization of a GSH Conjugate Efflux Pathway in the Rat Lens.

Breast cancer resistance protein, the multidrug resistance protein 4 and P-glycoprotein are not involved in the active secretion of PhIP in the rat distal colon.
Title: The colon carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) is actively secreted in the distal colon of the rat: an integrated view on the role of PhIP transport and metabolism in PhIP-induced colon carcinogenesis.

sustained repression and translocation of Ntcp and the expression of Mrp4 at the basolateral membrane seem to be responsible for the high blood bile acids levels after massive hepatectomy
Title: Sustained repression and translocation of Ntcp and expression of Mrp4 for cholestasis after rat 90% partial hepatectomy.

ANF signals via natriuretic peptide receptor-C coupled to the phospholipase C-protein kinase C pathway to increase secretin-induced efflux of cAMP, probably through MPR-4 in pancreas
Title: Atrial natriuretic factor stimulates efflux of cAMP in rat exocrine pancreas via multidrug resistance-associated proteins.

The following Abcc4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Abcc4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa13095	NM_133411.1 Latest version!	Rattus norvegicus ATP binding cassette subfamily C member 4 (Abcc4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	16	$643.30 $919.00
ORa44249	XM_008770939.1 Latest version!	Rattus norvegicus ATP binding cassette subfamily C member 4 (Abcc4), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$643.30 $919.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Abcc4 ( NM_133411.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_596902.1 Rattus norvegicus ATP binding cassette subfamily C member 4 (Abcc4), mRNA.

Price & Availability↑

CloneID	ORa13095
Clone ID Related Accession (Same CDS sequence)	NM_133411.1
Accession Version	NM_133411.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3978bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-16
Organism	Rattus norvegicus(Norway rat)
Product	multidrug resistance-associated protein 4
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY533524.1. On Mar 26, 2005 this sequence version replaced XM_341375.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY533524.1, AF534126.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGCTGCCGG TGCACACCGA GGTGAAACCC AACCCGCTGC AGGACGCCAA CCTCTGCTCG 
CGCTTGTTCT TCTGGTGGCT CAACCCGTTG TTTAAAGCTG GACATAAGCG GAGATTGGAA 
GAAGATGACA TGTTTTCAGT GCTTCCAGAA GATCGCTCAA AGCACCTTGG AGAGGAGTTG 
CAAGGGTACT GGGATAAAGA AGTTCTGCGA GCCAAGAAGG ACGCTCGGAA GCCTTCCTTA 
ACGAAGGCAA TCGTGAAGTG TTACTGGAAA TCTTACCTGA TTTTGGGAAT TTTTACGTTA 
ATTGAGGAGA CCACCCGAGT AGTTCAGCCC ATATTTTTAG GGAAAATTAT TGATTATTTT 
GAGAAGTATG ACTCTGACGA CTCGGCCGCT TTGCACACAG CTTACGGCTA CGCGGCGGTG 
CTGTCGCTGT GCACGCTCAT CCTGGCCATA CTACATCACT TGTATTTCTA CCACGTGCAG 
TGCGCCGGGA TGAGGATACG GGTCGCCATG TGCCACATGA TTTACCGGAA GGCTCTCCGG 
CTAAGTAACT CGGCCATGGG GAAGACAACC ACGGGCCAGA TAGTCAACCT GCTGTCCAAC 
GACGTGAACA AGTTTGACCA GGTGACCATC TTCTTGCACT TCCTGTGGGC GGGGCCGCTG 
CAAGCCATAG GGGTAACCAT CCTTCTCTGG GTGGAAATCG GAATCTCCTG TCTGGCGGGC 
CTGGCCATTC TGGTTATTCT GCTGCCTCTG CAAAGCTGCA TCGGGAAACT GTTCTCGTCA 
CTGCGGAGTA AAACAGCGGC TTTCACGGAT GCCAGGTTCC GGACCATGAA TGAAGTGATA 
ACGGGCATGA GGATAATAAA GATGTACGCG TGGGAGAAGT CATTCGCCGA CCTCATAACC 
AATCTGAGAA AGAAGGAAAT TTCTAAGATT CTGGGCAGCT CCTACCTCAG AGGGATGAAC 
ATGGCGTCGT TTTTCATTGC AAACAAAGTC ATCCTGTTCG TGACCTTCAC CACCTATGTG 
CTGCTTGGCA ATAAGATTAC ATCTAGCCAC GTGTTCGTGG CCATGACTCT GTATGGTGCT 
GTCCGGTTGA CAGTTACCCT CTTCTTCCCA TCAGCCATTG AGAGAGTGTC AGAGGCCGTC 
GTCAGCGTTC GGAGGATCAA GAACTTTCTG TTACTCGATG AACTGCCAGA GCGCAAAGCC 
CAGGAACCAT CTGATGGCAA AGCCATCGTT CACGTGCAAG ATTTTACCGC TTTCTGGGAC 
AAGGCATTAG ACACTCCTAC CCTGCAAGGT CTTTCCTTCA CTGCCAGACC TGGTGAGTTG 
TTAGCTGTGG TCGGCCCAGT CGGAGCAGGC AAGTCGTCCC TGTTGAGCGC GGTGCTCGGT 
GAGCTGCCTC CCACCAGTGG GCTGGTCAGC GTGCACGGGA GGATCGCCTA CGTTTCCCAG 
CAGCCCTGGG TGTTCTCAGG AACCGTGAGG AGCAATATTT TATTTGGGAG GAAATACGAG 
AAAGAACGCT ACGAGAAAGT CATCAAGGCC TGTGCTCTGA AGAAGGACTT GCAACTTCTG 
GAGGACGGGG ATCTGACTGT CATAGGCGAC CGGGGAGCCA CGCTGAGCGG AGGCCAGAAA 
GCACGGGTGA ACTTGGCACG GGCAGTCTAC CAGGATGCCG ACATCTACCT CCTCGATGAT 
CCGCTCAGTG CTGTTGATGC AGAAGTGGGC AAGCACCTGT TCCAGCTGTG TATCTGCCAG 
ACTTTGCACG AGAAGATCAC CATTTTAGTG ACTCACCAGT TACAGTACCT CAAAGCTGCA 
AGCCACATCC TCATACTAAA AGATGGCGAA ATGGTGCAGA AGGGGACTTA CACCGAGTTT 
CTGAAGTCTG GTGTAGATTT CGGTTCCCTG CTAAAGAAGG AAAATGAGGA AGCAGAGCCC 
TCCCCTGTCC CAGGAACACC GACACTCAGG AACCGAACCT TCTCCGAGGC CTCGATTTGG 
TCTCAACAGT CATCCAGACC CTCGTTGAAA GACGGGGTCC CAGATGCCCA AGATGCAGAG 
AATACTCAGG CAGCTCAACC CGAGGAGAGC CGTTCAGAAG GGAGAATCGG CTTCAAGGCC 
TACAAGAACT ACTTCTCTGC AGGCGCATCC TGGTTTTTCA TTATTTTCCT CGTTCTGCTT 
AACCTGATGG GTCAGGTTTT CTACGTTCTT CAGGACTGGT GGCTTTCCCA CTGGGCGAAT 
AGGCAAGGTG CCCTGAATGA CACCAAAAAC GCGAACGGGA ATGTAACCGG GACCCTCGAT 
CTCAGCTGGT ACTTAGGGAT TTACACAGGT TTAACTGCGG TCACAGTCCT CTTTGGCATA 
GCGAGATCCC TGCTGGTGTT CTATGTCCTT GTGAATGCTT CCCAGACTCT GCACAACAGG 
ATGTTCGAGT CGATCCTGAA GGCACCGGTG TTGTTCTTCG ATAGAAATCC AATAGGAAGG 
ATTTTAAATC GTTTCTCCAA GGACATCGGA CACATGGACG ACTTGCTTCC CCTAACGTTT 
CTAGACTTCA TCCAGACCTT GCTCCTTGTT GTAAGTGTGA TCGCCGTGGC GGCGGCCGTG 
ATCCCTTGGA TCCTCATACC CCTGGTTCCA CTCTCCATCA TCTTTGTGGT CCTTCGGAGA 
TATTTCTTAG AAACGTCGCG GGACGTCAAG CGCCTGGAGT CCACAACACG GAGCCCGGTA 
TTCTCCCATT TATCATCCTC CCTCCAGGGA CTCTGGACCA TCCGTGCCTA TAAGGCTGAA 
GAGAGGTGTC AGGAGCTGTT TGATGCACAC CAGGACTTGC ATTCAGAGGC TTGGTTCTTG 
TTCCTGACGA CATCAAGATG GTTCGCCGTG CGTCTGGACG CCATCTGCGC CGTCTTTGTC 
ATCGTCGTTG CCTTCGGGTC CCTGGTTCTG GCAAAGACCT TGGATGCTGG GCAGGTTGGC 
TTGGCCTTGT CCTACTCCCT CACGCTCATG GGGATGTTCC AGTGGTCTGT GAGACAGAGC 
GCCGAAGTAG AGAATATGAT GATTTCTGTG GAGAGGGTGA TTGAATACAC GGACCTAGAG 
AAGGAGGCGC CTTGGGAATG CAGGAAGCGC CCACCCCCAG GCTGGCCCCA CGAAGGAGTA 
ATTGTCTTCG ACAATGTGAA CTTCACCTAC AGCTTGGACG GGCCCCTTGT TCTGAAGCAC 
CTGACCGCAC TCATCAAGTC ACGAGAAAAG GTTGGAATTG TGGGAAGAAC TGGAGCTGGA 
AAAAGTTCCC TCATCTCAGC CCTCTTCAGG TTGTCAGAAC CTGAGGGGAA AATCTGGATT 
GATAAGATCT TGACGACTGA AATTGGACTT CACGATTTAA GGAAGAAAAT GTCAATCATA 
CCTCAGGAAC CTGTCCTGTT CACTGGAACC ATGAGGAAGA ACCTGGACCC CTTTAATGAG 
CACTCGGACG AGGAGCTGTG GAAAGCCCTA GAGGAGGTAC AACTTAAAGA GGCCATAGAA 
GATCTTCCTG GTAAAATGGA CACTGAACTA GCAGAATCTG GATCCAATTT CAGTGTTGGA 
CAGAGACAGT TAGTGTGCCT TGCGAGGGCA ATTCTGAAGA AAAACCGGAT ACTGATCATT 
GATGAAGCAA CTGCAAATGT GGATCCGAGA ACTGACGAGT TAATACAACA GAAAATCCGG 
GAGAAGTTTG CCCAGTGCAC TGTTCTCACC ATTGCTCACA GACTGAACAC CATCATTGAC 
AGCGACAAGA TAATGGTTTT GGATTCGGGA AGACTGAGAG AATATGATGA GCCGTATGTT 
TTGCTGCAGA ATCCAGAGAG CCTCTTTTAC AAGATGGTTC AGCAGCTGGG TAAGGGCGAA 
GCCGCTGCCC TCACCGAAAC AGCAAAACAG GTGTACTTCA GACGGAATTA TCCGGATATT 
GCATTCAGCA GCCCTGCGGT TATGAGCACC TCCAACGGAC AGCCCTCCGC CTTAACGATA 
TTTGAAACAG CATTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_596902.1
CDS	1..3978
Translation	MLPVHTEVKPNPLQDANLCSRLFFWWLNPLFKAGHKRRLEEDDMFSVLPEDRSKHLGEELQGYWDKEVLRAKKDARKPSLTKAIVKCYWKSYLILGIFTLIEETTRVVQPIFLGKIIDYFEKYDSDDSAALHTAYGYAAVLSLCTLILAILHHLYFYHVQCAGMRIRVAMCHMIYRKALRLSNSAMGKTTTGQIVNLLSNDVNKFDQVTIFLHFLWAGPLQAIGVTILLWVEIGISCLAGLAILVILLPLQSCIGKLFSSLRSKTAAFTDARFRTMNEVITGMRIIKMYAWEKSFADLITNLRKKEISKILGSSYLRGMNMASFFIANKVILFVTFTTYVLLGNKITSSHVFVAMTLYGAVRLTVTLFFPSAIERVSEAVVSVRRIKNFLLLDELPERKAQEPSDGKAIVHVQDFTAFWDKALDTPTLQGLSFTARPGELLAVVGPVGAGKSSLLSAVLGELPPTSGLVSVHGRIAYVSQQPWVFSGTVRSNILFGRKYEKERYEKVIKACALKKDLQLLEDGDLTVIGDRGATLSGGQKARVNLARAVYQDADIYLLDDPLSAVDAEVGKHLFQLCICQTLHEKITILVTHQLQYLKAASHILILKDGEMVQKGTYTEFLKSGVDFGSLLKKENEEAEPSPVPGTPTLRNRTFSEASIWSQQSSRPSLKDGVPDAQDAENTQAAQPEESRSEGRIGFKAYKNYFSAGASWFFIIFLVLLNLMGQVFYVLQDWWLSHWANRQGALNDTKNANGNVTGTLDLSWYLGIYTGLTAVTVLFGIARSLLVFYVLVNASQTLHNRMFESILKAPVLFFDRNPIGRILNRFSKDIGHMDDLLPLTFLDFIQTLLLVVSVIAVAAAVIPWILIPLVPLSIIFVVLRRYFLETSRDVKRLESTTRSPVFSHLSSSLQGLWTIRAYKAEERCQELFDAHQDLHSEAWFLFLTTSRWFAVRLDAICAVFVIVVAFGSLVLAKTLDAGQVGLALSYSLTLMGMFQWSVRQSAEVENMMISVERVIEYTDLEKEAPWECRKRPPPGWPHEGVIVFDNVNFTYSLDGPLVLKHLTALIKSREKVGIVGRTGAGKSSLISALFRLSEPEGKIWIDKILTTEIGLHDLRKKMSIIPQEPVLFTGTMRKNLDPFNEHSDEELWKALEEVQLKEAIEDLPGKMDTELAESGSNFSVGQRQLVCLARAILKKNRILIIDEATANVDPRTDELIQQKIREKFAQCTVLTIAHRLNTIIDSDKIMVLDSGRLREYDEPYVLLQNPESLFYKMVQQLGKGEAAALTETAKQVYFRRNYPDIAFSSPAVMSTSNGQPSALTIFETAL

Target ORF information:

RefSeq Version	NM_133411.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus ATP binding cassette subfamily C member 4 (Abcc4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_133411.1

ORF Insert Sequence:

ATGCTGCCGG TGCACACCGA GGTGAAACCC AACCCGCTGC AGGACGCCAA CCTCTGCTCG 
CGCTTGTTCT TCTGGTGGCT CAACCCGTTG TTTAAAGCTG GACATAAGCG GAGATTGGAA 
GAAGATGACA TGTTTTCAGT GCTTCCAGAA GATCGCTCAA AGCACCTTGG AGAGGAGTTG 
CAAGGGTACT GGGATAAAGA AGTTCTGCGA GCCAAGAAGG ACGCTCGGAA GCCTTCCTTA 
ACGAAGGCAA TCGTGAAGTG TTACTGGAAA TCTTACCTGA TTTTGGGAAT TTTTACGTTA 
ATTGAGGAGA CCACCCGAGT AGTTCAGCCC ATATTTTTAG GGAAAATTAT TGATTATTTT 
GAGAAGTATG ACTCTGACGA CTCGGCCGCT TTGCACACAG CTTACGGCTA CGCGGCGGTG 
CTGTCGCTGT GCACGCTCAT CCTGGCCATA CTACATCACT TGTATTTCTA CCACGTGCAG 
TGCGCCGGGA TGAGGATACG GGTCGCCATG TGCCACATGA TTTACCGGAA GGCTCTCCGG 
CTAAGTAACT CGGCCATGGG GAAGACAACC ACGGGCCAGA TAGTCAACCT GCTGTCCAAC 
GACGTGAACA AGTTTGACCA GGTGACCATC TTCTTGCACT TCCTGTGGGC GGGGCCGCTG 
CAAGCCATAG GGGTAACCAT CCTTCTCTGG GTGGAAATCG GAATCTCCTG TCTGGCGGGC 
CTGGCCATTC TGGTTATTCT GCTGCCTCTG CAAAGCTGCA TCGGGAAACT GTTCTCGTCA 
CTGCGGAGTA AAACAGCGGC TTTCACGGAT GCCAGGTTCC GGACCATGAA TGAAGTGATA 
ACGGGCATGA GGATAATAAA GATGTACGCG TGGGAGAAGT CATTCGCCGA CCTCATAACC 
AATCTGAGAA AGAAGGAAAT TTCTAAGATT CTGGGCAGCT CCTACCTCAG AGGGATGAAC 
ATGGCGTCGT TTTTCATTGC AAACAAAGTC ATCCTGTTCG TGACCTTCAC CACCTATGTG 
CTGCTTGGCA ATAAGATTAC ATCTAGCCAC GTGTTCGTGG CCATGACTCT GTATGGTGCT 
GTCCGGTTGA CAGTTACCCT CTTCTTCCCA TCAGCCATTG AGAGAGTGTC AGAGGCCGTC 
GTCAGCGTTC GGAGGATCAA GAACTTTCTG TTACTCGATG AACTGCCAGA GCGCAAAGCC 
CAGGAACCAT CTGATGGCAA AGCCATCGTT CACGTGCAAG ATTTTACCGC TTTCTGGGAC 
AAGGCATTAG ACACTCCTAC CCTGCAAGGT CTTTCCTTCA CTGCCAGACC TGGTGAGTTG 
TTAGCTGTGG TCGGCCCAGT CGGAGCAGGC AAGTCGTCCC TGTTGAGCGC GGTGCTCGGT 
GAGCTGCCTC CCACCAGTGG GCTGGTCAGC GTGCACGGGA GGATCGCCTA CGTTTCCCAG 
CAGCCCTGGG TGTTCTCAGG AACCGTGAGG AGCAATATTT TATTTGGGAG GAAATACGAG 
AAAGAACGCT ACGAGAAAGT CATCAAGGCC TGTGCTCTGA AGAAGGACTT GCAACTTCTG 
GAGGACGGGG ATCTGACTGT CATAGGCGAC CGGGGAGCCA CGCTGAGCGG AGGCCAGAAA 
GCACGGGTGA ACTTGGCACG GGCAGTCTAC CAGGATGCCG ACATCTACCT CCTCGATGAT 
CCGCTCAGTG CTGTTGATGC AGAAGTGGGC AAGCACCTGT TCCAGCTGTG TATCTGCCAG 
ACTTTGCACG AGAAGATCAC CATTTTAGTG ACTCACCAGT TACAGTACCT CAAAGCTGCA 
AGCCACATCC TCATACTAAA AGATGGCGAA ATGGTGCAGA AGGGGACTTA CACCGAGTTT 
CTGAAGTCTG GTGTAGATTT CGGTTCCCTG CTAAAGAAGG AAAATGAGGA AGCAGAGCCC 
TCCCCTGTCC CAGGAACACC GACACTCAGG AACCGAACCT TCTCCGAGGC CTCGATTTGG 
TCTCAACAGT CATCCAGACC CTCGTTGAAA GACGGGGTCC CAGATGCCCA AGATGCAGAG 
AATACTCAGG CAGCTCAACC CGAGGAGAGC CGTTCAGAAG GGAGAATCGG CTTCAAGGCC 
TACAAGAACT ACTTCTCTGC AGGCGCATCC TGGTTTTTCA TTATTTTCCT CGTTCTGCTT 
AACCTGATGG GTCAGGTTTT CTACGTTCTT CAGGACTGGT GGCTTTCCCA CTGGGCGAAT 
AGGCAAGGTG CCCTGAATGA CACCAAAAAC GCGAACGGGA ATGTAACCGG GACCCTCGAT 
CTCAGCTGGT ACTTAGGGAT TTACACAGGT TTAACTGCGG TCACAGTCCT CTTTGGCATA 
GCGAGATCCC TGCTGGTGTT CTATGTCCTT GTGAATGCTT CCCAGACTCT GCACAACAGG 
ATGTTCGAGT CGATCCTGAA GGCACCGGTG TTGTTCTTCG ATAGAAATCC AATAGGAAGG 
ATTTTAAATC GTTTCTCCAA GGACATCGGA CACATGGACG ACTTGCTTCC CCTAACGTTT 
CTAGACTTCA TCCAGACCTT GCTCCTTGTT GTAAGTGTGA TCGCCGTGGC GGCGGCCGTG 
ATCCCTTGGA TCCTCATACC CCTGGTTCCA CTCTCCATCA TCTTTGTGGT CCTTCGGAGA 
TATTTCTTAG AAACGTCGCG GGACGTCAAG CGCCTGGAGT CCACAACACG GAGCCCGGTA 
TTCTCCCATT TATCATCCTC CCTCCAGGGA CTCTGGACCA TCCGTGCCTA TAAGGCTGAA 
GAGAGGTGTC AGGAGCTGTT TGATGCACAC CAGGACTTGC ATTCAGAGGC TTGGTTCTTG 
TTCCTGACGA CATCAAGATG GTTCGCCGTG CGTCTGGACG CCATCTGCGC CGTCTTTGTC 
ATCGTCGTTG CCTTCGGGTC CCTGGTTCTG GCAAAGACCT TGGATGCTGG GCAGGTTGGC 
TTGGCCTTGT CCTACTCCCT CACGCTCATG GGGATGTTCC AGTGGTCTGT GAGACAGAGC 
GCCGAAGTAG AGAATATGAT GATTTCTGTG GAGAGGGTGA TTGAATACAC GGACCTAGAG 
AAGGAGGCGC CTTGGGAATG CAGGAAGCGC CCACCCCCAG GCTGGCCCCA CGAAGGAGTA 
ATTGTCTTCG ACAATGTGAA CTTCACCTAC AGCTTGGACG GGCCCCTTGT TCTGAAGCAC 
CTGACCGCAC TCATCAAGTC ACGAGAAAAG GTTGGAATTG TGGGAAGAAC TGGAGCTGGA 
AAAAGTTCCC TCATCTCAGC CCTCTTCAGG TTGTCAGAAC CTGAGGGGAA AATCTGGATT 
GATAAGATCT TGACGACTGA AATTGGACTT CACGATTTAA GGAAGAAAAT GTCAATCATA 
CCTCAGGAAC CTGTCCTGTT CACTGGAACC ATGAGGAAGA ACCTGGACCC CTTTAATGAG 
CACTCGGACG AGGAGCTGTG GAAAGCCCTA GAGGAGGTAC AACTTAAAGA GGCCATAGAA 
GATCTTCCTG GTAAAATGGA CACTGAACTA GCAGAATCTG GATCCAATTT CAGTGTTGGA 
CAGAGACAGT TAGTGTGCCT TGCGAGGGCA ATTCTGAAGA AAAACCGGAT ACTGATCATT 
GATGAAGCAA CTGCAAATGT GGATCCGAGA ACTGACGAGT TAATACAACA GAAAATCCGG 
GAGAAGTTTG CCCAGTGCAC TGTTCTCACC ATTGCTCACA GACTGAACAC CATCATTGAC 
AGCGACAAGA TAATGGTTTT GGATTCGGGA AGACTGAGAG AATATGATGA GCCGTATGTT 
TTGCTGCAGA ATCCAGAGAG CCTCTTTTAC AAGATGGTTC AGCAGCTGGG TAAGGGCGAA 
GCCGCTGCCC TCACCGAAAC AGCAAAACAG GTGTACTTCA GACGGAATTA TCCGGATATT 
GCATTCAGCA GCCCTGCGGT TATGAGCACC TCCAACGGAC AGCCCTCCGC CTTAACGATA 
TTTGAAACAG CATTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Abcc4 ( XM_008770939.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008769161.1 Rattus norvegicus ATP binding cassette subfamily C member 4 (Abcc4), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa44249
Clone ID Related Accession (Same CDS sequence)	XM_008770939.1
Accession Version	XM_008770939.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3978bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	multidrug resistance-associated protein 4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005114.4) and transcript sequence (AF534126.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 95 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END##

ATGCTGCCGG TGCACACCGA GGTGAAACCC AACCCGCTGC AGGACGCCAA CCTCTGCTCG 
CGCTTGTTCT TCTGGTGGCT CAACCCGTTG TTTAAAGCTG GACATAAGCG GAGATTGGAA 
GAAGATGACA TGTTTTCAGT GCTTCCAGAA GATCGCTCAA AGCACCTTGG AGAGGAGTTG 
CAAGGGTACT GGGATAAAGA AGTTCTGCGA GCCAAGAAGG ACGCTCGGAA GCCTTCCTTA 
ACGAAGGCAA TCGTGAAGTG TTACTGGAAA TCTTACCTGA TTTTGGGAAT TTTTACGTTA 
ATTGAGGAGA CCACCCGAGT AGTTCAGCCC ATATTTTTAG GGAAAATTAT TGATTATTTT 
GAGAAGTATG ACTCTGACGA CTCGGCCGCT TTGCACACAG CTTACGGCTA CGCGGCGGTG 
CTGTCGCTGT GCACGCTCAT CCTGGCCATA CTACATCACT TGTATTTCTA CCACGTGCAG 
TGCGCCGGGA TGAGGATACG GGTCGCCATG TGCCACATGA TTTACCGGAA GGCTCTCCGG 
CTAAGTAACT CGGCCATGGG GAAGACAACC ACGGGCCAGA TAGTCAACCT GCTGTCCAAC 
GACGTGAACA AGTTTGACCA GGTGACCATC TTCTTGCACT TCCTGTGGGC GGGGCCGCTG 
CAAGCCATAG GGGTAACCAT CCTTCTCTGG GTGGAAATCG GAATCTCCTG TCTGGCGGGC 
CTGGCCATTC TGGTTATTCT GCTGCCTCTG CAAAGCTGCA TCGGGAAACT GTTCTCGTCA 
CTGCGGAGTA AAACAGCGGC TTTCACGGAT GCCAGGATCC GGACCATGAA TGAAGTGATA 
ACGGGCATGA GGATAATAAA GATGTACGCG TGGGAGAAGT CATTCGCCGA CCTCATAACC 
AATCTGAGAA AGAAGGAAAT TTCTAAGATT CTGGGCAGCT CCTACCTCAG AGGGATGAAC 
ATGGCGTCGT TTTTCATTGC AAACAAAGTC ATCCTGTTCG TGACCTTCAC CACCTATGTG 
CTGCTTGGCA ATAAGATTAC AGCTAGCCAC GTGTTCGTGG CCATGACTCT GTATGGTGCT 
GTCCGGTTGA CAGTTACCCT CTTCTTCCCA TCAGCCATTG AGAGAGTGTC AGAGGCCGTC 
GTCAGCGTTC GGAGGATCAA GAACTTTCTG TTACTCGATG AACTGCCAGA GCGCAAAGCC 
CAGGAACCAT CTGATGGCAA AGCCATCGTT CACGTGCAAG ATTTTACCGC TTTCTGGGAC 
AAGGCATTAG ACACTCCTAC CCTGCAAGGT CTTTCCTTCA CTGCCAGACC TGGTGAGTTG 
TTAGCTGTGG TCGGCCCAGT CGGAGCAGGC AAGTCGTCCC TGTTGAGCGC GGTGCTCGGT 
GAGCTGCCTC CCACCAGTGG GCTGGTCAGC GTGCACGGGA GGATCGCCTA CGTTTCCCAG 
CAGCCCTGGG TGTTCTCAGG AACCGTGAGG AGCAATATTT TATTTGGGAG GAAATACGAG 
AAAGAACGCT ACGAGAAAGT CATCAAGGCC TGTGCTCTGA AGAAGGACTT GCAACTTCTG 
GAGGACGGGG ATCTGACTGT CATAGGCGAC CGGGGAGCCA CGCTGAGCGG AGGCCAGAAA 
GCACGGGTGA ACTTGGCACG GGCAGTCTAC CAGGATGCCG ACATCTACCT CCTCGATGAT 
CCGCTCAGTG CTGTTGATGC AGAAGTGGGC AAGCACCTGT TCCAGCTGTG TATCTGCCAG 
ACTTTGCACG AGAAGATCAC CATTTTAGTG ACTCACCAGT TACAGTACCT CAAAGCTGCA 
AGCCACATCC TCATACTAAA AGATGGCGAA ATGGTGCAGA AGGGGACTTA CACCGAGTTT 
CTGAAGTCTG GTGTAGATTT CGGTTCCCTG CTAAAGAAGG AAAATGAGGA AGCAGAGCCC 
TCCCCTGTCC CAGGAACACC GACACTCAGG AACCGAACCT TCTCCGAGGC CTCGATTTGG 
TCTCAACAGT CATCCAGACC CTCATTGAAA GACGGGGTCC CAGATGCCCA AGATGCAGAG 
AATACTCAGG CAGCTCAACC CGAGGAGAGC CGTTCAGAAG GGAGAATCGG CTTCAAGGCC 
TACAAGAACT ACTTCTCTGC AGGCGCATCC TGGTTTTTCA TTATTTTCCT CGTTCTGCTT 
AACCTGATGG GTCAGGTTTT CTACGTTCTT CAGGACTGGT GGCTTTCCCA CTGGGCGAAT 
AGGCAAGGTG CCCTGAACGA CACCAAAAAC GCGAACGGGA ATGTAACCGG GACCCTCGAT 
CTCAGCTGGT ACTTAGGGAT TTACACAGGT TTAACTGCGG TCACAGTCCT CTTTGGCATA 
GCGAGATCCC TGCTGGTGTT CTATGTCCTT GTGAATGCTT CCCAGACTCT GCACAACAGG 
ATGTTCGAGT CGATCCTGAA GGCACCGGTG TTGTTCTTCG ATAGAAATCC AATAGGAAGG 
ATTTTAAATC GTTTCTCCAA GGACATCGGA CACATGGACG ACTTGCTTCC CCTAACGTTT 
CTAGACTTCA TCCAGACCTT GCTCCTTGTT GTAAGTGTGA TCGCCGTGGC GGCGGCCGTG 
ATCCCTTGGA TCCTCATACC CCTGGTTCCA CTCTCCATCA TCTTTGTGGT CCTTCGGAGA 
TATTTCTTAG AAACGTCGCG GGACGTCAAG CGCCTGGAGT CCACAACACG GAGCCCGGTA 
TTCTCCCATT TATCATCCTC CCTCCAGGGA CTCTGGACCA TCCGTGCCTA TAAGGCTGAA 
GAGAGGTGTC AGGAGCTGTT TGATGCACAC CAGGACTTGC ATTCAGAGGC TTGGTTCTTG 
TTCCTGACGA CATCAAGATG GTTCGCCGTG CGTCTGGACG CCATCTGCGC CGTCTTTGTC 
ATCGTCGTTG CCTTCGGGTC CCTGGTTCTG GCAAAGACCT TGGATGCTGG GCAGGTTGGC 
TTGGCCTTGT CCTACTCCCT CACGCTCATG GGGATGTTCC AGTGGTCTGT GAGACAGAGC 
GCCGAAGTAG AGAATATGAT GATTTCTGTG GAGAGGGTGA TTGAATACAC GGACCTAGAG 
AAGGAGGCGC CTTGGGAATG CAGGAAGCGC CCACCCCCAG GCTGGCCCCA CGAAGGAGTA 
ATTGTCTTCG ACAATGTGAA CTTCACCTAC AGCTTGGACG GGCCCCTTGT TCTGAAGCAC 
CTGACCGCAC TCATCAAGTC ACGAGAAAAG GTTGGAATTG TGGGAAGAAC TGGAGCTGGA 
AAAAGTTCCC TCATCTCAGC CCTCTTCAGG TTGTCAGAAC CTGAGGGGAA AATCTGGATT 
GATAAGATCT TGACGACTGA AATTGGACTT CACGATTTAA GGAAGAAAAT GTCAATCATA 
CCTCAGGAAC CTGTCCTGTT CACTGGAACC ATGAGGAAGA ACCTGGACCC CTTTAATGAG 
CACTCAGACG AGGAGCTGTG GAAAGCCCTA GAGGAGGTAC AACTTAAAGA GGCCATAGAA 
GATCTTCCTG GTAAAATGGA CACTGAACTA GCAGAATCTG GATCCAATTT CAGTGTTGGA 
CAGAGACAGT TAGTGTGCCT TGCGAGGGCA ATTCTGAAGA AAAACCGGAT ACTGATCATT 
GATGAAGCAA CTGCAAATGT GGATCCGAGA ACTGACGAGT TAATACAACA GAAAATCCGG 
GAGAAGTTTG CCCAGTGCAC TGTTCTCACC ATTGCTCACA GACTGAACAC CATCATTGAC 
AGCGACAAGA TAATGGTTTT GGATTCGGGA AGACTGAGAG AATATGATGA GCCGTATGTT 
TTGCTGCAGA ATCCAGAGAG CCTCTTTTAC AAGATGGTTC AGCAGCTGGG TAAGGGCGAA 
GCCGCTGCCC TCACCGAAAC AGCAAAACAG GTGTACTTCA GACGGAATTA TCCGGATATT 
GCATTCAGCA GCCCTGCGGT TATGAGCACC TCCAACGGAC AGCCCTCCGC CTTAACGATA 
TTTGAAACAG CATTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008769161.1
CDS	389..4366
Translation	MLPVHTEVKPNPLQDANLCSRLFFWWLNPLFKAGHKRRLEEDDMFSVLPEDRSKHLGEELQGYWDKEVLRAKKDARKPSLTKAIVKCYWKSYLILGIFTLIEETTRVVQPIFLGKIIDYFEKYDSDDSAALHTAYGYAAVLSLCTLILAILHHLYFYHVQCAGMRIRVAMCHMIYRKALRLSNSAMGKTTTGQIVNLLSNDVNKFDQVTIFLHFLWAGPLQAIGVTILLWVEIGISCLAGLAILVILLPLQSCIGKLFSSLRSKTAAFTDARIRTMNEVITGMRIIKMYAWEKSFADLITNLRKKEISKILGSSYLRGMNMASFFIANKVILFVTFTTYVLLGNKITASHVFVAMTLYGAVRLTVTLFFPSAIERVSEAVVSVRRIKNFLLLDELPERKAQEPSDGKAIVHVQDFTAFWDKALDTPTLQGLSFTARPGELLAVVGPVGAGKSSLLSAVLGELPPTSGLVSVHGRIAYVSQQPWVFSGTVRSNILFGRKYEKERYEKVIKACALKKDLQLLEDGDLTVIGDRGATLSGGQKARVNLARAVYQDADIYLLDDPLSAVDAEVGKHLFQLCICQTLHEKITILVTHQLQYLKAASHILILKDGEMVQKGTYTEFLKSGVDFGSLLKKENEEAEPSPVPGTPTLRNRTFSEASIWSQQSSRPSLKDGVPDAQDAENTQAAQPEESRSEGRIGFKAYKNYFSAGASWFFIIFLVLLNLMGQVFYVLQDWWLSHWANRQGALNDTKNANGNVTGTLDLSWYLGIYTGLTAVTVLFGIARSLLVFYVLVNASQTLHNRMFESILKAPVLFFDRNPIGRILNRFSKDIGHMDDLLPLTFLDFIQTLLLVVSVIAVAAAVIPWILIPLVPLSIIFVVLRRYFLETSRDVKRLESTTRSPVFSHLSSSLQGLWTIRAYKAEERCQELFDAHQDLHSEAWFLFLTTSRWFAVRLDAICAVFVIVVAFGSLVLAKTLDAGQVGLALSYSLTLMGMFQWSVRQSAEVENMMISVERVIEYTDLEKEAPWECRKRPPPGWPHEGVIVFDNVNFTYSLDGPLVLKHLTALIKSREKVGIVGRTGAGKSSLISALFRLSEPEGKIWIDKILTTEIGLHDLRKKMSIIPQEPVLFTGTMRKNLDPFNEHSDEELWKALEEVQLKEAIEDLPGKMDTELAESGSNFSVGQRQLVCLARAILKKNRILIIDEATANVDPRTDELIQQKIREKFAQCTVLTIAHRLNTIIDSDKIMVLDSGRLREYDEPYVLLQNPESLFYKMVQQLGKGEAAALTETAKQVYFRRNYPDIAFSSPAVMSTSNGQPSALTIFETAL

Target ORF information:

RefSeq Version	XM_008770939.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus ATP binding cassette subfamily C member 4 (Abcc4), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008770939.1

ORF Insert Sequence:

ATGCTGCCGG TGCACACCGA GGTGAAACCC AACCCGCTGC AGGACGCCAA CCTCTGCTCG 
CGCTTGTTCT TCTGGTGGCT CAACCCGTTG TTTAAAGCTG GACATAAGCG GAGATTGGAA 
GAAGATGACA TGTTTTCAGT GCTTCCAGAA GATCGCTCAA AGCACCTTGG AGAGGAGTTG 
CAAGGGTACT GGGATAAAGA AGTTCTGCGA GCCAAGAAGG ACGCTCGGAA GCCTTCCTTA 
ACGAAGGCAA TCGTGAAGTG TTACTGGAAA TCTTACCTGA TTTTGGGAAT TTTTACGTTA 
ATTGAGGAGA CCACCCGAGT AGTTCAGCCC ATATTTTTAG GGAAAATTAT TGATTATTTT 
GAGAAGTATG ACTCTGACGA CTCGGCCGCT TTGCACACAG CTTACGGCTA CGCGGCGGTG 
CTGTCGCTGT GCACGCTCAT CCTGGCCATA CTACATCACT TGTATTTCTA CCACGTGCAG 
TGCGCCGGGA TGAGGATACG GGTCGCCATG TGCCACATGA TTTACCGGAA GGCTCTCCGG 
CTAAGTAACT CGGCCATGGG GAAGACAACC ACGGGCCAGA TAGTCAACCT GCTGTCCAAC 
GACGTGAACA AGTTTGACCA GGTGACCATC TTCTTGCACT TCCTGTGGGC GGGGCCGCTG 
CAAGCCATAG GGGTAACCAT CCTTCTCTGG GTGGAAATCG GAATCTCCTG TCTGGCGGGC 
CTGGCCATTC TGGTTATTCT GCTGCCTCTG CAAAGCTGCA TCGGGAAACT GTTCTCGTCA 
CTGCGGAGTA AAACAGCGGC TTTCACGGAT GCCAGGATCC GGACCATGAA TGAAGTGATA 
ACGGGCATGA GGATAATAAA GATGTACGCG TGGGAGAAGT CATTCGCCGA CCTCATAACC 
AATCTGAGAA AGAAGGAAAT TTCTAAGATT CTGGGCAGCT CCTACCTCAG AGGGATGAAC 
ATGGCGTCGT TTTTCATTGC AAACAAAGTC ATCCTGTTCG TGACCTTCAC CACCTATGTG 
CTGCTTGGCA ATAAGATTAC AGCTAGCCAC GTGTTCGTGG CCATGACTCT GTATGGTGCT 
GTCCGGTTGA CAGTTACCCT CTTCTTCCCA TCAGCCATTG AGAGAGTGTC AGAGGCCGTC 
GTCAGCGTTC GGAGGATCAA GAACTTTCTG TTACTCGATG AACTGCCAGA GCGCAAAGCC 
CAGGAACCAT CTGATGGCAA AGCCATCGTT CACGTGCAAG ATTTTACCGC TTTCTGGGAC 
AAGGCATTAG ACACTCCTAC CCTGCAAGGT CTTTCCTTCA CTGCCAGACC TGGTGAGTTG 
TTAGCTGTGG TCGGCCCAGT CGGAGCAGGC AAGTCGTCCC TGTTGAGCGC GGTGCTCGGT 
GAGCTGCCTC CCACCAGTGG GCTGGTCAGC GTGCACGGGA GGATCGCCTA CGTTTCCCAG 
CAGCCCTGGG TGTTCTCAGG AACCGTGAGG AGCAATATTT TATTTGGGAG GAAATACGAG 
AAAGAACGCT ACGAGAAAGT CATCAAGGCC TGTGCTCTGA AGAAGGACTT GCAACTTCTG 
GAGGACGGGG ATCTGACTGT CATAGGCGAC CGGGGAGCCA CGCTGAGCGG AGGCCAGAAA 
GCACGGGTGA ACTTGGCACG GGCAGTCTAC CAGGATGCCG ACATCTACCT CCTCGATGAT 
CCGCTCAGTG CTGTTGATGC AGAAGTGGGC AAGCACCTGT TCCAGCTGTG TATCTGCCAG 
ACTTTGCACG AGAAGATCAC CATTTTAGTG ACTCACCAGT TACAGTACCT CAAAGCTGCA 
AGCCACATCC TCATACTAAA AGATGGCGAA ATGGTGCAGA AGGGGACTTA CACCGAGTTT 
CTGAAGTCTG GTGTAGATTT CGGTTCCCTG CTAAAGAAGG AAAATGAGGA AGCAGAGCCC 
TCCCCTGTCC CAGGAACACC GACACTCAGG AACCGAACCT TCTCCGAGGC CTCGATTTGG 
TCTCAACAGT CATCCAGACC CTCATTGAAA GACGGGGTCC CAGATGCCCA AGATGCAGAG 
AATACTCAGG CAGCTCAACC CGAGGAGAGC CGTTCAGAAG GGAGAATCGG CTTCAAGGCC 
TACAAGAACT ACTTCTCTGC AGGCGCATCC TGGTTTTTCA TTATTTTCCT CGTTCTGCTT 
AACCTGATGG GTCAGGTTTT CTACGTTCTT CAGGACTGGT GGCTTTCCCA CTGGGCGAAT 
AGGCAAGGTG CCCTGAACGA CACCAAAAAC GCGAACGGGA ATGTAACCGG GACCCTCGAT 
CTCAGCTGGT ACTTAGGGAT TTACACAGGT TTAACTGCGG TCACAGTCCT CTTTGGCATA 
GCGAGATCCC TGCTGGTGTT CTATGTCCTT GTGAATGCTT CCCAGACTCT GCACAACAGG 
ATGTTCGAGT CGATCCTGAA GGCACCGGTG TTGTTCTTCG ATAGAAATCC AATAGGAAGG 
ATTTTAAATC GTTTCTCCAA GGACATCGGA CACATGGACG ACTTGCTTCC CCTAACGTTT 
CTAGACTTCA TCCAGACCTT GCTCCTTGTT GTAAGTGTGA TCGCCGTGGC GGCGGCCGTG 
ATCCCTTGGA TCCTCATACC CCTGGTTCCA CTCTCCATCA TCTTTGTGGT CCTTCGGAGA 
TATTTCTTAG AAACGTCGCG GGACGTCAAG CGCCTGGAGT CCACAACACG GAGCCCGGTA 
TTCTCCCATT TATCATCCTC CCTCCAGGGA CTCTGGACCA TCCGTGCCTA TAAGGCTGAA 
GAGAGGTGTC AGGAGCTGTT TGATGCACAC CAGGACTTGC ATTCAGAGGC TTGGTTCTTG 
TTCCTGACGA CATCAAGATG GTTCGCCGTG CGTCTGGACG CCATCTGCGC CGTCTTTGTC 
ATCGTCGTTG CCTTCGGGTC CCTGGTTCTG GCAAAGACCT TGGATGCTGG GCAGGTTGGC 
TTGGCCTTGT CCTACTCCCT CACGCTCATG GGGATGTTCC AGTGGTCTGT GAGACAGAGC 
GCCGAAGTAG AGAATATGAT GATTTCTGTG GAGAGGGTGA TTGAATACAC GGACCTAGAG 
AAGGAGGCGC CTTGGGAATG CAGGAAGCGC CCACCCCCAG GCTGGCCCCA CGAAGGAGTA 
ATTGTCTTCG ACAATGTGAA CTTCACCTAC AGCTTGGACG GGCCCCTTGT TCTGAAGCAC 
CTGACCGCAC TCATCAAGTC ACGAGAAAAG GTTGGAATTG TGGGAAGAAC TGGAGCTGGA 
AAAAGTTCCC TCATCTCAGC CCTCTTCAGG TTGTCAGAAC CTGAGGGGAA AATCTGGATT 
GATAAGATCT TGACGACTGA AATTGGACTT CACGATTTAA GGAAGAAAAT GTCAATCATA 
CCTCAGGAAC CTGTCCTGTT CACTGGAACC ATGAGGAAGA ACCTGGACCC CTTTAATGAG 
CACTCAGACG AGGAGCTGTG GAAAGCCCTA GAGGAGGTAC AACTTAAAGA GGCCATAGAA 
GATCTTCCTG GTAAAATGGA CACTGAACTA GCAGAATCTG GATCCAATTT CAGTGTTGGA 
CAGAGACAGT TAGTGTGCCT TGCGAGGGCA ATTCTGAAGA AAAACCGGAT ACTGATCATT 
GATGAAGCAA CTGCAAATGT GGATCCGAGA ACTGACGAGT TAATACAACA GAAAATCCGG 
GAGAAGTTTG CCCAGTGCAC TGTTCTCACC ATTGCTCACA GACTGAACAC CATCATTGAC 
AGCGACAAGA TAATGGTTTT GGATTCGGGA AGACTGAGAG AATATGATGA GCCGTATGTT 
TTGCTGCAGA ATCCAGAGAG CCTCTTTTAC AAGATGGTTC AGCAGCTGGG TAAGGGCGAA 
GCCGCTGCCC TCACCGAAAC AGCAAAACAG GTGTACTTCA GACGGAATTA TCCGGATATT 
GCATTCAGCA GCCCTGCGGT TATGAGCACC TCCAACGGAC AGCCCTCCGC CTTAACGATA 
TTTGAAACAG CATTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Modulation of transport and metabolism of bile acids and bilirubin by chlorogenic acid against hepatotoxity and cholestasis in bile duct ligation rats: involvement of SIRT1-mediated deacetylation of FXR and PGC-1?.
Journal of hepato-biliary-pancreatic sciences(2018 Jan)
Zhu L,Wang L,Cao F,Liu P,Bao H,Yan Y,Dong X,Wang D,Wang Z,Gong P

Nrf2 signaling increases expression of ATP-binding cassette subfamily C mRNA transcripts at the blood-brain barrier following hypoxia-reoxygenation stress.
Fluids and barriers of the CNS14(1)6(2017 Mar)
Ibbotson K,Yell J,Ronaldson PT

Effect of Multi Drug Resistance Protein 4 (MRP4) Inhibition on the Pharmacokinetics and Pharmacodynamics of Ciprofloxacin in Normal and Rats with LPS-Induced Inflammation.
European journal of drug metabolism and pharmacokinetics41(6)733-741(2016 Dec)
Prasad VG,Achanta S,Tammineni YR,Alla GR,Thirtham MR,Rao GS

Identification and Functional Characterization of a GSH Conjugate Efflux Pathway in the Rat Lens.
Investigative ophthalmology & visual science56(9)5256-68(2015 Aug)
Umapathy A,Li B,Donaldson PJ,Lim JC

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Abcc4 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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