Fxyd3 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Fxyd3
Entrez Gene ID	116831
Full Name	FXYD domain-containing ion transport regulator 3
Synonyms	MAT8
General protein information	Preferred Names FXYD domain-containing ion transport regulator 3 Names FXYD domain-containing ion transport regulator 3 sodium/potassium-transporting ATPase subunit FXYD3
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q21
Summary	This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Mouse FXYD5 has been termed RIC (Related to Ion Channel). FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. [provided by RefSeq, Jul 2008].

mRNA and Protein(s)

mRNA	Protein	Name
XM_006228819.3	XP_006228881.1	FXYD domain-containing ion transport regulator 3 isoform X1
NM_172317.2	NP_758528.1	FXYD domain-containing ion transport regulator 3 precursor

Pathways from BioSystems

Homologies

Xenopus tropicalis (tropical clawed frog)	fxyd3	NP_001039081.1
	FXYD3	XP_002801227.1
Homo sapiens (human)	FXYD3	NP_001129479.1
Canis lupus familiaris (dog)	FXYD3	XP_005616779.1
Mus musculus (house mouse)	Fxyd3	NP_032583.1
Rattus norvegicus (Norway rat)	Fxyd3	NP_758528.1

Gene Ontology
Bibliography

Related articles in PubMed

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR
Journal of proteome research8(3)1304-14(2009 Mar)

FXYD3 (Mat-8), a new regulator of Na,K-ATPase.
Crambert G, Li C, Claeys D, Geering K
Molecular biology of the cell16(5)2363-71(2005 May)

The FXYD gene family of small ion transport regulators or channels: cDNA sequence, protein signature sequence, and expression.
Sweadner KJ, Rael E
Genomics68(1)41-56(2000 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Fxyd3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Fxyd3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa03259	NM_172317.2 Latest version!	Rattus norvegicus FXYD domain-containing ion transport regulator 3 (Fxyd3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
ORa22605	XM_006228819.3 Latest version!	Rattus norvegicus FXYD domain-containing ion transport regulator 3 (Fxyd3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Fxyd3 ( NM_172317.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_758528.1 Rattus norvegicus FXYD domain-containing ion transport regulator 3 (Fxyd3), mRNA.

Price & Availability↑

CloneID	ORa03259
Clone ID Related Accession (Same CDS sequence)	NM_172317.2
Accession Version	NM_172317.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 267bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Rattus norvegicus(Norway rat)
Product	FXYD domain-containing ion transport regulator 3 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DY471861.1 and BG373727.1. On Aug 28, 2007 this sequence version replaced NM_172317.1. ##Evidence-Data-START## Transcript exon combination :: AW142066.1, DY471861.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCAAGAGT TTGCTCTGAG CCTGTTGGTC CTTCTAGCAG GCCTGCCTAC TTTGGATGCC 
AATGACCCTG AAGATAAAGA TAGCCCTTTC TACTATGATT GGCACAGCCT CCGAGTCGGC 
GGGCTCATCT GTGCAGGGAT TCTCTGTGCC CTGGGCATTA TAGTTCTCAT GAGTGGCAAG 
TGCAAATGCA AGTTCAGCCA GAAACCCAGC CACCGTCCAG GAGATGGGCC ACCCCTCATC 
ACACCAGGCT CTGCTCACAA CTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_758528.1
CDS	30..296
Translation	MQEFALSLLVLLAGLPTLDANDPEDKDSPFYYDWHSLRVGGLICAGILCALGIIVLMSGKCKCKFSQKPSHRPGDGPPLITPGSAHNC

Target ORF information:

RefSeq Version	NM_172317.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus FXYD domain-containing ion transport regulator 3 (Fxyd3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_172317.2

ORF Insert Sequence:

ATGCAAGAGT TTGCTCTGAG CCTGTTGGTC CTTCTAGCAG GCCTGCCTAC TTTGGATGCC 
AATGACCCTG AAGATAAAGA TAGCCCTTTC TACTATGATT GGCACAGCCT CCGAGTCGGC 
GGGCTCATCT GTGCAGGGAT TCTCTGTGCC CTGGGCATTA TAGTTCTCAT GAGTGGCAAG 
TGCAAATGCA AGTTCAGCCA GAAACCCAGC CACCGTCCAG GAGATGGGCC ACCCCTCATC 
ACACCAGGCT CTGCTCACAA CTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Fxyd3 ( XM_006228819.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006228881.1 Rattus norvegicus FXYD domain-containing ion transport regulator 3 (Fxyd3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa22605
Clone ID Related Accession (Same CDS sequence)	XM_006228819.3
Accession Version	XM_006228819.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 273bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	FXYD domain-containing ion transport regulator 3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006228819.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAAGAGT TTGCTCTGAG CCTGTTGGTC CTTCTAGCAG GCCTGCCTAC TTTGGATGCC 
AATGACCCTG AAGATAAAGA TAGCCCTTTC TACTATGATT GGCACAGCCT CCGAGTCGGC 
GGGCTCATCT GTGCAGGGAT TCTCTGTGCC CTGGGCATTA TAGTTCTCAT GAGTGGCAAG 
TGCAAATGCA AGTTCAGCCA GAAACCCAGC CACCGTCCAG GAGATGGGCC ACCCCTCATC 
ACACCAGGTA TGACACAGGA TGATTGGGGG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006228881.1
CDS	132..404
Translation	MQEFALSLLVLLAGLPTLDANDPEDKDSPFYYDWHSLRVGGLICAGILCALGIIVLMSGKCKCKFSQKPSHRPGDGPPLITPGMTQDDWG

Target ORF information:

RefSeq Version	XM_006228819.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus FXYD domain-containing ion transport regulator 3 (Fxyd3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006228819.3

ORF Insert Sequence:

ATGCAAGAGT TTGCTCTGAG CCTGTTGGTC CTTCTAGCAG GCCTGCCTAC TTTGGATGCC 
AATGACCCTG AAGATAAAGA TAGCCCTTTC TACTATGATT GGCACAGCCT CCGAGTCGGC 
GGGCTCATCT GTGCAGGGAT TCTCTGTGCC CTGGGCATTA TAGTTCTCAT GAGTGGCAAG 
TGCAAATGCA AGTTCAGCCA GAAACCCAGC CACCGTCCAG GAGATGGGCC ACCCCTCATC 
ACACCAGGTA TGACACAGGA TGATTGGGGG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Journal of proteome research8(3)1304-14(2009 Mar)
Gonzalez-Begne M,Lu B,Han X,Hagen FK,Hand AR,Melvin JE,Yates JR

FXYD3 (Mat-8), a new regulator of Na,K-ATPase.
Molecular biology of the cell16(5)2363-71(2005 May)
Crambert G,Li C,Claeys D,Geering K

The FXYD gene family of small ion transport regulators or channels: cDNA sequence, protein signature sequence, and expression.
Genomics68(1)41-56(2000 Aug)
Sweadner KJ,Rael E

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Fxyd3 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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