Nox1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Mechanisms of N?acetylcysteine in reducing monocrotaline?induced pulmonary hypertension in rats: Inhibiting the expression of Nox1 in pulmonary vascular smooth muscle cells.
Yu W, Ji W, Mi L, Lin C
Molecular medicine reports16(5)6148-6155(2017 Nov)

Aluminum exposure at human dietary levels promotes vascular dysfunction and increases blood pressure in rats: A concerted action of NAD(P)H oxidase and COX-2.
Martinez CS, Piagette JT, Escobar AG, Mart?n ?, Palacios R, Pe?anha FM, Vassallo DV, Exley C, Alonso MJ, Miguel M, Salaices M, Wiggers GA
Toxicology39010-21(2017 09)

Zinc regulates Nox1 expression through a NF-?B and mitochondrial ROS dependent mechanism to induce senescence of vascular smooth muscle cells.
Salazar G, Huang J, Feresin RG, Zhao Y, Griendling KK
Free radical biology & medicine108225-235(2017 Jul)

Results point to an excess of reactive oxygen species mainly from NAD(P)H oxidase after aluminum exposure and increased vascular prostanoids from COX-2 acting in concert to decrease NO bioavailability, thus inducing vascular dysfunction and increasing blood pressure.
Title: Aluminum exposure at human dietary levels promotes vascular dysfunction and increases blood pressure in rats: A concerted action of NAD(P)H oxidase and COX-2.

Studied the physiology of advanced oxidation protein products (AOPPs) in beta-cell destruction and dysfunction. Found exposure of cells to AOPPs induced an increase in Bax expression, caspase-3 activity, and apoptosis as well as a decrease in Bcl-2 expression. AOPP challenge rapidly increased the production of intracellular superoxide by activation of NADPH oxidases.
Title: Advanced oxidation protein products promote NADPH oxidase-dependent ?-cell destruction and dysfunction through the Bcl-2/Bax apoptotic pathway.

Curcumin attenuated liver damage through the downregulation of Rac1, Rac1-GTP, and NOX1 as well as reduced oxidative stress in the serum and liver tissue of biliary duct-ligated rats.
Title: Hepatoprotective effects of curcumin in rats after bile duct ligation via downregulation of Rac1 and NOX1.

Quercetin demonstrated hepatoprotective activity against BDL-induced liver injury through increasing antioxidant capacity of the liver tissue, while preventing the production of Rac1, and NOX1.
Title: Quercetin protects liver injury induced by bile duct ligation via attenuation of Rac1 and NADPH oxidase1 expression in rats.

NOX activity and expression differ according to the skeletal muscle fiber type, as well as antioxidant defense.
Title: Differential Expression of NADPH Oxidases Depends on Skeletal Muscle Fiber Type in Rats.