Gene Symbol | KISS1 |
Entrez Gene ID | 101107719 |
Full Name | KiSS-1 metastasis suppressor |
Gene Type | protein-coding |
Organism | Ovis aries(sheep) |
ORF » Species Summary » Ovis aries » KISS1 cDNA ORF clone
Gene Symbol | KISS1 |
Entrez Gene ID | 101107719 |
Full Name | KiSS-1 metastasis suppressor |
Gene Type | protein-coding |
Organism | Ovis aries(sheep) |
mRNA | Protein | Name |
---|---|---|
NM_001306104.1 | NP_001293033.1 | metastasis-suppressor KiSS-1 precursor |
XM_027975561.1 | XP_027831362.1 | metastasis-suppressor KiSS-1 isoform X1 |
Pubertal Escape From Estradiol Negative Feedback in Ewe Lambs Is Not Accounted for by Decreased ESR1 mRNA or Protein in Kisspeptin Neurons.
Bedenbaugh MN, D'Oliveira M, Cardoso RC, Hileman SM, Williams GL, Amstalden M
Endocrinology159(1)426-438(2018 Jan)
Expression of kisspeptin protein in hypothalamus and LH profile of growing female lambs.
Polkowska J, W?jcik-G?adysz A, Chmielewska N, Wa?kowska M
Reproduction, fertility, and development(2017 Sep)
Relationships between leptin, KiSS-1/GPR54 expression and TSH secretion from pituitary cells of pubertal ewes in vitro.
Radwa?ska P, Kosior-Korzecka U
Research in veterinary science105180-7(2016 Apr)
Influences of melatonin treatment, melatonin receptor 1A (MTNR1A) and kisspeptin (KiSS-1) gene polymorphisms on first conception in Sarda ewe lambs.
Luridiana S, Mura MC, Daga C, Cosso G, Bodano S, Farci F, Zidda F, Carcangiu V
Reproduction, fertility, and development28(6)750-6(2016 Apr)
Kisspeptin is a component of the pulse generator for GnRH secretion in female sheep but not the pulse generator.
Ezzat A, Pereira A, Clarke IJ
Endocrinology156(5)1828-37(2015 May)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
leptin directly affected kisspeptin-1 expression in pituitary cells of pubertal ewes.
Title: Relationships between leptin, KiSS-1/GPR54 expression and TSH secretion from pituitary cells of pubertal ewes in vitro.
Data suggest a positive effect of melatonin treatment on the time of first conception in ewe lambs in Sardinia. The G/G genotype of an SNP in Mtnr1a (G612A; melatonin receptor 1A) influences the reproductive response to melatonin treatment; no influence was found for an SNP in KiSS1 (G1035A; kisspeptin-1) or another SNP in Mtnr1a (C606T).
Title: Influences of melatonin treatment, melatonin receptor 1A (MTNR1A) and kisspeptin (KiSS-1) gene polymorphisms on first conception in Sarda ewe lambs.
kisspeptin from cells of the arcuate nucleus drives pulsatile secretion of GnRH at the level of the median eminence, but this may involve "upstream" input from glutamate cells. The pulse generator for GnRH secretion involves more than 1 element.
Title: Kisspeptin is a component of the pulse generator for GnRH secretion in female sheep but not the pulse generator.
introduction of male sheep to seasonally anestrous female sheep activates kisspeptin neurons and other cells in the hypothalamus, leading to increased GnRH/LH secretion
Title: Kisspeptin signaling is required for the luteinizing hormone response in anestrous ewes following the introduction of males.
Results suggest that kisspeptin is a gatekeeper to female ovine puberty and raise the possibility that neurokinin B (NKB) may also play a role, albeit through different means.
Title: Evidence of a role for kisspeptin and neurokinin B in puberty of female sheep.
The following KISS1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the KISS1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSm61531 | |
Clone ID Related Accession (Same CDS sequence) | XM_027975561.1 | |
Accession Version | XM_027975561.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 687bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-02-05 | |
Organism | Ovis aries(sheep) | |
Product | metastasis-suppressor KiSS-1 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_040263.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Ovis aries Annotation Release 103 Annotation Version :: 103 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTTAGCCA CGGGCACCAG AAGGCAGGAG CCAGCAGCAG GGAGCGGGAG GGCTGCACTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_027831362.1 |
CDS | 840..1526 |
Translation |
Target ORF information:
Target ORF information:
|
XM_027975561.1 |
1 | ATGTTAGCCA CGGGCACCAG AAGGCAGGAG CCAGCAGCAG GGAGCGGGAG GGCTGCACTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OSm28642 | |
Clone ID Related Accession (Same CDS sequence) | NM_001306104.1 | |
Accession Version | NM_001306104.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 408bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-09-24 | |
Organism | Ovis aries(sheep) | |
Product | metastasis-suppressor KiSS-1 precursor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JQ716394.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: JQ716394.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA104494984, SAMEA104495026 [ECO:0000350] ##Evidence-Data-END## |
1 | ATGAACGTGC TGCTTTCCCG GCAGCTGATG CTCTTCCTTT GTGCCACCGC CTTCAGGGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001293033.1 |
CDS | 254..661 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001306104.1 |
1 | ATGAACGTGC TGCTTTCCCG GCAGCTGATG CTCTTCCTTT GTGCCACCGC CTTCAGGGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Pubertal Escape From Estradiol Negative Feedback in Ewe Lambs Is Not Accounted for by Decreased ESR1 mRNA or Protein in Kisspeptin Neurons. |
Expression of kisspeptin protein in hypothalamus and LH profile of growing female lambs. |
Relationships between leptin, KiSS-1/GPR54 expression and TSH secretion from pituitary cells of pubertal ewes in vitro. |
Influences of melatonin treatment, melatonin receptor 1A (MTNR1A) and kisspeptin (KiSS-1) gene polymorphisms on first conception in Sarda ewe lambs. |
Kisspeptin is a component of the pulse generator for GnRH secretion in female sheep but not the pulse generator. |