BST2 cDNA ORF clone, Macaca mulatta(Rhesus monkey)

Gene
Clones
gRNAs

Summary

Gene Symbol	BST2
Entrez Gene ID	719092
Full Name	bone marrow stromal cell antigen 2
Synonyms	BST-2,CD317
Gene Type	protein-coding
Organism	Macaca mulatta(Rhesus monkey)

mRNA and Protein(s)

mRNA	Protein	Name
XM_015123240.1	XP_014978726.1	bone marrow stromal antigen 2 isoform X1
NM_001161666.1	NP_001155138.1	bone marrow stromal antigen 2
XM_015123240.2	XP_014978726.2	bone marrow stromal antigen 2 isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	BST2	NP_004326.1
Pan troglodytes (chimpanzee)	BST2	NP_001177409.1
Canis lupus familiaris (dog)	BST2	XP_865603.1
	BST2	NP_001155138.1

Gene Ontology
Bibliography

Related articles in PubMed

Increased BST2 expression during simian immunodeficiency virus infection is not a determinant of disease progression in rhesus monkeys.
Mussil B, Javed A, T?pfer K, Sauermann U, Sopper S
Retrovirology1292(2015 Nov)

A new rhesus macaque assembly and annotation for next-generation sequencing analyses.
Zimin AV, Cornish AS, Maudhoo MD, Gibbs RM, Zhang X, Pandey S, Meehan DT, Wipfler K, Bosinger SE, Johnson ZP, Tharp GK, Mar?ais G, Roberts M, Ferguson B, Fox HS, Treangen T, Salzberg SL, Yorke JA, Norgren RB Jr
Biology direct9(1)20(2014 Oct)

Functional antagonism of rhesus macaque and chimpanzee BST-2 by HIV-1 Vpu is mediated by cytoplasmic domain interactions.
Yoshida T, Koyanagi Y, Strebel K
Journal of virology87(24)13825-36(2013 Dec)

Tetherin upregulation in simian immunodeficiency virus-infected macaques.
Rahmberg AR, Neidermyer WJ Jr, Breed MW, Alvarez X, Midkiff CC, Piatak M Jr, Lifson JD, Evans DT
Journal of virology87(24)13917-21(2013 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

the detected relationship between BST2 expression and viral load as well as with MX1 indicate a common regulation by the interferon response and suggest rather limited influence of BST2 in vivo on the simian immunodeficiency virus infection outcome
Title: Increased BST2 expression during simian immunodeficiency virus infection is not a determinant of disease progression in rhesus monkeys.

A 5-amino-acid sequence in the rhesus BST-2 cytoplasmic domain accounts for the interaction with Vpu and for rhesus BST-2 antagonism by HIV-1 Vpu.
Title: Functional antagonism of rhesus macaque and chimpanzee BST-2 by HIV-1 Vpu is mediated by cytoplasmic domain interactions.

Simian immunodeficiency virus infection results in rapid upregulation of BST-2 on peripheral blood lymphocytes.
Title: Tetherin upregulation in simian immunodeficiency virus-infected macaques.

Data suggest that rhesus macaque tetherin and Simian immunodeficiency virus Nef undergo physical interaction leading to removal of tetherin from plasma membrane by clathrin-mediated endocytosis.
Title: Tetherin/BST-2 antagonism by Nef depends on a direct physical interaction between Nef and tetherin, and on clathrin-mediated endocytosis.

The following BST2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the BST2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMb04684	NM_001161666.1 Latest version!	Macaca mulatta bone marrow stromal cell antigen 2 (BST2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00
OMb53260	XM_015123240.1 Latest version!	Macaca mulatta bone marrow stromal cell antigen 2 (BST2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$104.30 $149.00
OMb75565	XM_015123240.2 Latest version!	Macaca mulatta bone marrow stromal cell antigen 2 (BST2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

BST2 ( NM_001161666.1 ) cDNA ORF clone, Macaca mulatta(Rhesus monkey) -> NP_001155138.1 Macaca mulatta bone marrow stromal cell antigen 2 (BST2), mRNA.

Price & Availability↑

CloneID	OMb04684
Clone ID Related Accession (Same CDS sequence)	NM_001161666.1
Accession Version	NM_001161666.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 549bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-27
Organism	Macaca mulatta(Rhesus monkey)
Product	bone marrow stromal antigen 2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from FJ868941.1. On Jun 11, 2009 this sequence version replaced XM_001113599.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: FJ868941.1, FJ943431.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA27162418, SAMEA4688315 [ECO:0000350] ##Evidence-Data-END##

ATGGCACCTA TTTTGTATGA CTATCGCAAA ATGCCCATGG GTGACATTTG GAAGGAAGAC 
GGGGACAAGC GCTGTAAACT GGTGATAGGA ATTCTGGGGC TCCTGGTCAT AGTGCTTCTG 
GGGGTGCTCC TGATTTTCTT CATCATCAAG GCCAACAGCG AGGCCTGCCA GGATGGCCTC 
CGGGCAGTGA TGGAGTGTCG CAATGTCACC TATCTCCTGC AACAAGAGCT GGCCGAGGCC 
CAGCGGGGCT TTCGGGATGC AGAGGCCCAG GCTGTCACCT GCAACCAGAC TGTGATGGCC 
CTAATGGCTT CCCTGGATGC AGAGAAGGCC CAAGGACGAA AGAAAGTGGA GGAGCTTGAG 
GGGGAGATCA CTACATTGAA CCACAAGCTT CAGGACGCGT CTGCGGAGGT GGAGCGACTG 
AGAAGAGAAA ACCACGTCTT AAACGCGAGA ATCGCGGACA CGGACTCCGC CAGCTCCCAA 
GACTCCAGCT GCGCGGCAGA GCCCCCGCTC CTGATTCTGC TGCTGGGCTT GAGCGCTCTG 
CTGCTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001155138.1
CDS	1..549
Translation	MAPILYDYRKMPMGDIWKEDGDKRCKLVIGILGLLVIVLLGVLLIFFIIKANSEACQDGLRAVMECRNVTYLLQQELAEAQRGFRDAEAQAVTCNQTVMALMASLDAEKAQGRKKVEELEGEITTLNHKLQDASAEVERLRRENHVLNARIADTDSASSQDSSCAAEPPLLILLLGLSALLL

Target ORF information:

RefSeq Version	NM_001161666.1
Organism	Macaca mulatta(Rhesus monkey)
Definition	Macaca mulatta bone marrow stromal cell antigen 2 (BST2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001161666.1

ORF Insert Sequence:

ATGGCACCTA TTTTGTATGA CTATCGCAAA ATGCCCATGG GTGACATTTG GAAGGAAGAC 
GGGGACAAGC GCTGTAAACT GGTGATAGGA ATTCTGGGGC TCCTGGTCAT AGTGCTTCTG 
GGGGTGCTCC TGATTTTCTT CATCATCAAG GCCAACAGCG AGGCCTGCCA GGATGGCCTC 
CGGGCAGTGA TGGAGTGTCG CAATGTCACC TATCTCCTGC AACAAGAGCT GGCCGAGGCC 
CAGCGGGGCT TTCGGGATGC AGAGGCCCAG GCTGTCACCT GCAACCAGAC TGTGATGGCC 
CTAATGGCTT CCCTGGATGC AGAGAAGGCC CAAGGACGAA AGAAAGTGGA GGAGCTTGAG 
GGGGAGATCA CTACATTGAA CCACAAGCTT CAGGACGCGT CTGCGGAGGT GGAGCGACTG 
AGAAGAGAAA ACCACGTCTT AAACGCGAGA ATCGCGGACA CGGACTCCGC CAGCTCCCAA 
GACTCCAGCT GCGCGGCAGA GCCCCCGCTC CTGATTCTGC TGCTGGGCTT GAGCGCTCTG 
CTGCTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

BST2 ( XM_015123240.1 ) cDNA ORF clone, Macaca mulatta(Rhesus monkey) -> XP_014978726.1 Macaca mulatta bone marrow stromal cell antigen 2 (BST2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMb53260
Clone ID Related Accession (Same CDS sequence)	XM_015123240.1
Accession Version	XM_015123240.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 549bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-12-20
Organism	Macaca mulatta(Rhesus monkey)
Product	bone marrow stromal antigen 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_014805772.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Macaca mulatta Annotation Release 102 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCACCTA TTTTGTATGA CTATCGCAAA ATGCCCATGG ATGACATTTG GAAGGAAGAC 
GGGGACAAGC GCTGTAAACT GGTGGTAGGA ATTCTGGGGC TCCTGGTCAT AGTGCTTCTG 
GGGGTGCCCC TGATTTTCTT CATCATCAAG GCCAACAGCG AGGCCTGCCA GGATGGCCTC 
CGGGCAGTGA TGGAGTGTCG CAATGTCACC TATCTCCTGC AACAAGAGCT GGCCGAGGCC 
CAGCGGGGCT TTCGGGATGC AGAGGCCCAG GCTGTCACCT GCAACCAGAC TGTGATGGCC 
CTAATGGCTT CCCTGGATGC AGAGAAGGCC CACGGACGAA AGAAAGTGGA GGAGCTTGAG 
GGGGAGATCA CTACATTGAA CCACAAGCTT CAGGACGCGT CTGCGGAGGT GGAGCGACTG 
AGAAGAGAAA ACCACGTCTT AAACGCGAGA ATCGCGGACA CGGACTCCGC CAGCCCCCAA 
GACTCCAGCT GCGCGGCAGA GCCCCCGCTC CTGATTCTGC TGCTGGGCTT GAGCGCTCTG 
CTGCTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_014978726.1
CDS	92..640
Translation	MAPILYDYRKMPMDDIWKEDGDKRCKLVVGILGLLVIVLLGVPLIFFIIKANSEACQDGLRAVMECRNVTYLLQQELAEAQRGFRDAEAQAVTCNQTVMALMASLDAEKAHGRKKVEELEGEITTLNHKLQDASAEVERLRRENHVLNARIADTDSASPQDSSCAAEPPLLILLLGLSALLL

Target ORF information:

RefSeq Version	XM_015123240.1
Organism	Macaca mulatta(Rhesus monkey)
Definition	Macaca mulatta bone marrow stromal cell antigen 2 (BST2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_015123240.1

ORF Insert Sequence:

ATGGCACCTA TTTTGTATGA CTATCGCAAA ATGCCCATGG ATGACATTTG GAAGGAAGAC 
GGGGACAAGC GCTGTAAACT GGTGGTAGGA ATTCTGGGGC TCCTGGTCAT AGTGCTTCTG 
GGGGTGCCCC TGATTTTCTT CATCATCAAG GCCAACAGCG AGGCCTGCCA GGATGGCCTC 
CGGGCAGTGA TGGAGTGTCG CAATGTCACC TATCTCCTGC AACAAGAGCT GGCCGAGGCC 
CAGCGGGGCT TTCGGGATGC AGAGGCCCAG GCTGTCACCT GCAACCAGAC TGTGATGGCC 
CTAATGGCTT CCCTGGATGC AGAGAAGGCC CACGGACGAA AGAAAGTGGA GGAGCTTGAG 
GGGGAGATCA CTACATTGAA CCACAAGCTT CAGGACGCGT CTGCGGAGGT GGAGCGACTG 
AGAAGAGAAA ACCACGTCTT AAACGCGAGA ATCGCGGACA CGGACTCCGC CAGCCCCCAA 
GACTCCAGCT GCGCGGCAGA GCCCCCGCTC CTGATTCTGC TGCTGGGCTT GAGCGCTCTG 
CTGCTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

BST2 ( XM_015123240.2 ) cDNA ORF clone, Macaca mulatta(Rhesus monkey) -> XP_014978726.2 Macaca mulatta bone marrow stromal cell antigen 2 (BST2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMb75565
Clone ID Related Accession (Same CDS sequence)	XM_015123240.2
Accession Version	XM_015123240.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 549bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-25
Organism	Macaca mulatta(Rhesus monkey)
Product	bone marrow stromal antigen 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_041772.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 23, 2019 this sequence version replaced XM_015123240.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Macaca mulatta Annotation Release 103 Annotation Version :: 103 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCACCTA TTTTGTATGA CTATTGCAAA ATGCCCATGG GTGACATTTG GAAGGAAGAC 
GGGGACAAGC GCTGTAAACT GGTGATAGGA ATTCTGGGGC TCCTGGTCAT AGTGCTTCTG 
GGGGTGCTCC TGATTTTCTT CATCATCAAG GCCAACAGCG AGGCCTGCCA GGATGGCCTC 
CGGGCAGTGA TGGAGTGTCG CAATGTCACC TATCTCCTGC AACAAGAGCT GGCCGAGGCC 
CAGCGGGGCT TTCGGGATGC AGAGGCCCAG GCTGTCACCT GCAACCAGAC TGTGATGGCC 
CTAATGGCTT CCCTGGATGC AGAGAAGGCC CACGGACGAA AGAAAGTGGA GGAGCTTGAG 
GGGGAGATCA CTACATTGAA CCACAAGCTT CAGGACGCGT CTGCGGAGGT GGAGCGACTG 
AGAAGAGAAA ACCACGTCTT AAACGCGAGA ATCGCGGACA CGGACTCCGC CAGCCCCCAA 
GACTCCAGCT GCGCGGCAGA GCCCCCGCTC CTGATTCTGC TGCTGGGCTT GAGCGCTCTG 
CTGCTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_014978726.2
CDS	104..652
Translation	MAPILYDYCKMPMGDIWKEDGDKRCKLVIGILGLLVIVLLGVLLIFFIIKANSEACQDGLRAVMECRNVTYLLQQELAEAQRGFRDAEAQAVTCNQTVMALMASLDAEKAHGRKKVEELEGEITTLNHKLQDASAEVERLRRENHVLNARIADTDSASPQDSSCAAEPPLLILLLGLSALLL

Target ORF information:

RefSeq Version	XM_015123240.2
Organism	Macaca mulatta(Rhesus monkey)
Definition	Macaca mulatta bone marrow stromal cell antigen 2 (BST2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_015123240.2

ORF Insert Sequence:

ATGGCACCTA TTTTGTATGA CTATTGCAAA ATGCCCATGG GTGACATTTG GAAGGAAGAC 
GGGGACAAGC GCTGTAAACT GGTGATAGGA ATTCTGGGGC TCCTGGTCAT AGTGCTTCTG 
GGGGTGCTCC TGATTTTCTT CATCATCAAG GCCAACAGCG AGGCCTGCCA GGATGGCCTC 
CGGGCAGTGA TGGAGTGTCG CAATGTCACC TATCTCCTGC AACAAGAGCT GGCCGAGGCC 
CAGCGGGGCT TTCGGGATGC AGAGGCCCAG GCTGTCACCT GCAACCAGAC TGTGATGGCC 
CTAATGGCTT CCCTGGATGC AGAGAAGGCC CACGGACGAA AGAAAGTGGA GGAGCTTGAG 
GGGGAGATCA CTACATTGAA CCACAAGCTT CAGGACGCGT CTGCGGAGGT GGAGCGACTG 
AGAAGAGAAA ACCACGTCTT AAACGCGAGA ATCGCGGACA CGGACTCCGC CAGCCCCCAA 
GACTCCAGCT GCGCGGCAGA GCCCCCGCTC CTGATTCTGC TGCTGGGCTT GAGCGCTCTG 
CTGCTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Increased BST2 expression during simian immunodeficiency virus infection is not a determinant of disease progression in rhesus monkeys.
Retrovirology1292(2015 Nov)
Mussil B,Javed A,T?pfer K,Sauermann U,Sopper S

A new rhesus macaque assembly and annotation for next-generation sequencing analyses.
Biology direct9(1)20(2014 Oct)
Zimin AV,Cornish AS,Maudhoo MD,Gibbs RM,Zhang X,Pandey S,Meehan DT,Wipfler K,Bosinger SE,Johnson ZP,Tharp GK,Mar?ais G,Roberts M,Ferguson B,Fox HS,Treangen T,Salzberg SL,Yorke JA,Norgren RB Jr

Functional antagonism of rhesus macaque and chimpanzee BST-2 by HIV-1 Vpu is mediated by cytoplasmic domain interactions.
Journal of virology87(24)13825-36(2013 Dec)
Yoshida T,Koyanagi Y,Strebel K

Tetherin upregulation in simian immunodeficiency virus-infected macaques.
Journal of virology87(24)13917-21(2013 Dec)
Rahmberg AR,Neidermyer WJ Jr,Breed MW,Alvarez X,Midkiff CC,Piatak M Jr,Lifson JD,Evans DT

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BST2 cDNA ORF clone, Macaca mulatta(Rhesus monkey)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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