Mnd1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Mnd1
Entrez Gene ID	76915
Full Name	meiotic nuclear divisions 1
Synonyms	2610034E18Rik,AI591601,Gaj
General protein information	Preferred Names meiotic nuclear divisions 1 Names meiotic nuclear division protein 1 homolog meiotic nuclear divisions 1 homolog mnd1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 3 Map Location: 3\|3 F1

mRNA and Protein(s)

mRNA	Protein	Name
XM_006502262.3	XP_006502325.1	meiotic nuclear division protein 1 homolog isoform X1
NM_029797.3	NP_084073.2	meiotic nuclear division protein 1 homolog
XM_006502262.4	XP_006502325.1	meiotic nuclear division protein 1 homolog isoform X1

Pathways from BioSystems

Homologies

Schizosaccharomyces pombe (fission yeast)	mcp7	NP_592991.1
Arabidopsis thaliana (thale cress)	ATMND1	NP_194646.2
Pan troglodytes (chimpanzee)	MND1	XP_517488.2
	MND1	XP_001087396.1
Canis lupus familiaris (dog)	MND1	XP_539771.2
Gallus gallus (chicken)	MND1	NP_001244242.1
Bos taurus (cattle)	MND1	NP_001033312.1
Mus musculus (house mouse)	Mnd1	NP_084073.2
Oryza sativa (rice)	Os09g0280600	NP_001062766.1
Xenopus tropicalis (tropical clawed frog)	mnd1	NP_001015849.1
Homo sapiens (human)	MND1	NP_115493.1
Rattus norvegicus (Norway rat)	Mnd1	XP_215595.5
Danio rerio (zebrafish)	mnd1	NP_001003597.1

Gene Ontology
Bibliography

Related articles in PubMed

Spatiotemporal regulation of GLI target genes in the mammalian limb bud.
Lewandowski JP, Du F, Zhang S, Powell MB, Falkenstein KN, Ji H, Vokes SA
Developmental biology406(1)92-103(2015 Oct)

Significance of ligand interactions involving Hop2-Mnd1 and the RAD51 and DMC1 recombinases in homologous DNA repair and XX ovarian dysgenesis.
Zhao W, Sung P
Nucleic acids research43(8)4055-66(2015 Apr)

HOP2-MND1 modulates RAD51 binding to nucleotides and DNA.
Bugreev DV, Huang F, Mazina OM, Pezza RJ, Voloshin ON, Camerini-Otero RD, Mazin AV
Nature communications54198(2014 Jun)

The dual role of HOP2 in mammalian meiotic homologous recombination.
Pezza RJ, Voloshin ON, Volodin AA, Boateng KA, Bellani MA, Mazin AV, Camerini-Otero RD
Nucleic acids research42(4)2346-57(2014 Feb)

Mechanistic insights into the role of Hop2-Mnd1 in meiotic homologous DNA pairing.
Zhao W, Saro D, Hammel M, Kwon Y, Xu Y, Rambo RP, Williams GJ, Chi P, Lu L, Pezza RJ, Camerini-Otero RD, Tainer JA, Wang HW, Sung P
Nucleic acids research42(2)906-17(2014 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

HOP2-MND1 enhances the interaction of RAD51 with nucleotide cofactors and modifies its DNA-binding specificity.
Title: HOP2-MND1 modulates RAD51 binding to nucleotides and DNA.

The Hop2-Mnd1 heterodimer efficiently condenses double-stranded DNA via formation of a bright spot or DNA condensate.
Title: Hop2-Mnd1 condenses DNA to stimulate the synapsis phase of DNA strand exchange.

Hop2/Mnd1 greatly stimulates Dmc1 to promote synaptic complex formation on long duplex DNAs
Title: Hop2/Mnd1 acts on two critical steps in Dmc1-promoted homologous pairing.

data reveal an interplay among Hop2, Mnd1 and Rad51 and Dmc1 in the formation of the first recombination intermediates during meiosis [Mnd1]
Title: The Hop2 and Mnd1 proteins act in concert with Rad51 and Dmc1 in meiotic recombination.

Characterization of the MND1 gene in Saccharomyces cerevisiae and identification of a potential homolog in mouse.
Title: The Mnd1 protein forms a complex with hop2 to promote homologous chromosome pairing and meiotic double-strand break repair.

The following Mnd1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Mnd1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu07495	NM_029797.3 Latest version!	Mus musculus meiotic nuclear divisions 1 (Mnd1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00
OMu32406	XM_006502262.4 Latest version!	Mus musculus meiotic nuclear divisions 1 (Mnd1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
View Old Accession Versions >>
OMu32406	XM_006502262.3	Mus musculus meiotic nuclear divisions 1 (Mnd1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Mnd1 ( NM_029797.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_084073.2 Mus musculus meiotic nuclear divisions 1 (Mnd1), mRNA.

Price & Availability↑

CloneID	OMu07495
Clone ID Related Accession (Same CDS sequence)	NM_029797.3
Accession Version	NM_029797.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 618bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-20
Organism	Mus musculus(house mouse)
Product	meiotic nuclear division protein 1 homolog
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY083009.1, BY710901.1 and BG070803.2. On Jun 20, 2009 this sequence version replaced NM_029797.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: CB193030.1, BC027741.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164143 [ECO:0000348] ##Evidence-Data-END##

ATGTCAAAGA AAAGAGGACT GAGTGGGGAG GAAAAGAGAA CCCGGATGAT GGAGATATTT 
TTTGAGACAA AAGATGTATT CCAGCTGAAA GACCTGGAGA AGCTTGCTCC CAAAGAGAAA 
GGCATAACCG CCATGTCAGT GAAGGAAGTC CTTCAGAGCC TAGTGGATGA CGGTATGGTT 
GACTGCGAGA GGATCGGGAC GTCCAATTAC TATTGGGCTT TTCCGAGCAA GGCTCTTCAT 
GCCAGGAAGC GCAAGTTGGA GGCTCTGAAC TCTCAGCTGT CAGAGGGAAG CCAGAAGCAT 
GCAGACTTAC AGAAGAGCAT TGAGAAAGCA AGAGTTGGCC GGCAAGAGAC GGAAGAACGA 
GCCATGCTTG CAAAAGAACT TTCTTCATTT CGAGACCAAA GGCAACAACT TAAGGCAGAA 
GTGGAAAAAT ATCGAGAATG TGACCCACAG GTTGTGGAAG AGATACGTGA AGCAAATAAA 
GTAGCTAAAG AAGCCGCCAA TCGATGGACT GATAACATAT TTGCAATAAA ATCCTGGGCC 
AAAAGAAAAT TTGGGTTTGA AGAAAGTAAA ATTGATAAAA ACTTTGGAAT TCCAGAAGAC 
TTTGACTACA TAGACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_084073.2
CDS	123..740
Translation	MSKKRGLSGEEKRTRMMEIFFETKDVFQLKDLEKLAPKEKGITAMSVKEVLQSLVDDGMVDCERIGTSNYYWAFPSKALHARKRKLEALNSQLSEGSQKHADLQKSIEKARVGRQETEERAMLAKELSSFRDQRQQLKAEVEKYRECDPQVVEEIREANKVAKEAANRWTDNIFAIKSWAKRKFGFEESKIDKNFGIPEDFDYID

Target ORF information:

RefSeq Version	NM_029797.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus meiotic nuclear divisions 1 (Mnd1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_029797.3

ORF Insert Sequence:

ATGTCAAAGA AAAGAGGACT GAGTGGGGAG GAAAAGAGAA CCCGGATGAT GGAGATATTT 
TTTGAGACAA AAGATGTATT CCAGCTGAAA GACCTGGAGA AGCTTGCTCC CAAAGAGAAA 
GGCATAACCG CCATGTCAGT GAAGGAAGTC CTTCAGAGCC TAGTGGATGA CGGTATGGTT 
GACTGCGAGA GGATCGGGAC GTCCAATTAC TATTGGGCTT TTCCGAGCAA GGCTCTTCAT 
GCCAGGAAGC GCAAGTTGGA GGCTCTGAAC TCTCAGCTGT CAGAGGGAAG CCAGAAGCAT 
GCAGACTTAC AGAAGAGCAT TGAGAAAGCA AGAGTTGGCC GGCAAGAGAC GGAAGAACGA 
GCCATGCTTG CAAAAGAACT TTCTTCATTT CGAGACCAAA GGCAACAACT TAAGGCAGAA 
GTGGAAAAAT ATCGAGAATG TGACCCACAG GTTGTGGAAG AGATACGTGA AGCAAATAAA 
GTAGCTAAAG AAGCCGCCAA TCGATGGACT GATAACATAT TTGCAATAAA ATCCTGGGCC 
AAAAGAAAAT TTGGGTTTGA AGAAAGTAAA ATTGATAAAA ACTTTGGAAT TCCAGAAGAC 
TTTGACTACA TAGACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Mnd1 ( XM_006502262.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006502325.1 Mus musculus meiotic nuclear divisions 1 (Mnd1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu32406
Clone ID Related Accession (Same CDS sequence)	XM_006502262.3 , XM_006502262.4
Accession Version	XM_006502262.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 543bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	meiotic nuclear division protein 1 homolog isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000069.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006502262.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCAAAGA AAAGAGGACT GAGTGGGGAG GAAAAGAGAA CCCGGATGAT GGAGATATTT 
TTTGAGACAA AAGATGTATT CCAGCTGAAA GACCTGGAGA AGCTTGCTCC CAAAGAGAAA 
GGCATAACCG CCATGTCAGT GAAGGAAGTC CTTCAGAGCC TAGTGGATGA CGGTATGGTT 
GACTGCGAGA GGATCGGGAC GTCCAATTAC TATTGGGCTT TTCCGAGCAA GGCTCTTCAT 
GCCAGGAAGC GCAAGTTGGA GGCTCTGAAC TCTCAGGAAG AACGAGCCAT GCTTGCAAAA 
GAACTTTCTT CATTTCGAGA CCAAAGGCAA CAACTTAAGG CAGAAGTGGA AAAATATCGA 
GAATGTGACC CACAGGTTGT GGAAGAGATA CGTGAAGCAA ATAAAGTAGC TAAAGAAGCC 
GCCAATCGAT GGACTGATAA CATATTTGCA ATAAAATCCT GGGCCAAAAG AAAATTTGGG 
TTTGAAGAAA GTAAAATTGA TAAAAACTTT GGAATTCCAG AAGACTTTGA CTACATAGAC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006502325.1
CDS	117..659
Translation	MSKKRGLSGEEKRTRMMEIFFETKDVFQLKDLEKLAPKEKGITAMSVKEVLQSLVDDGMVDCERIGTSNYYWAFPSKALHARKRKLEALNSQEERAMLAKELSSFRDQRQQLKAEVEKYRECDPQVVEEIREANKVAKEAANRWTDNIFAIKSWAKRKFGFEESKIDKNFGIPEDFDYID

Target ORF information:

RefSeq Version	XM_006502262.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus meiotic nuclear divisions 1 (Mnd1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006502262.3

ORF Insert Sequence:

ATGTCAAAGA AAAGAGGACT GAGTGGGGAG GAAAAGAGAA CCCGGATGAT GGAGATATTT 
TTTGAGACAA AAGATGTATT CCAGCTGAAA GACCTGGAGA AGCTTGCTCC CAAAGAGAAA 
GGCATAACCG CCATGTCAGT GAAGGAAGTC CTTCAGAGCC TAGTGGATGA CGGTATGGTT 
GACTGCGAGA GGATCGGGAC GTCCAATTAC TATTGGGCTT TTCCGAGCAA GGCTCTTCAT 
GCCAGGAAGC GCAAGTTGGA GGCTCTGAAC TCTCAGGAAG AACGAGCCAT GCTTGCAAAA 
GAACTTTCTT CATTTCGAGA CCAAAGGCAA CAACTTAAGG CAGAAGTGGA AAAATATCGA 
GAATGTGACC CACAGGTTGT GGAAGAGATA CGTGAAGCAA ATAAAGTAGC TAAAGAAGCC 
GCCAATCGAT GGACTGATAA CATATTTGCA ATAAAATCCT GGGCCAAAAG AAAATTTGGG 
TTTGAAGAAA GTAAAATTGA TAAAAACTTT GGAATTCCAG AAGACTTTGA CTACATAGAC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Mnd1 ( XM_006502262.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006502325.1 Mus musculus meiotic nuclear divisions 1 (Mnd1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu32406
Clone ID Related Accession (Same CDS sequence)	XM_006502262.3 , XM_006502262.4
Accession Version	XM_006502262.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 543bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	meiotic nuclear division protein 1 homolog isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000069.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006502262.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCAAAGA AAAGAGGACT GAGTGGGGAG GAAAAGAGAA CCCGGATGAT GGAGATATTT 
TTTGAGACAA AAGATGTATT CCAGCTGAAA GACCTGGAGA AGCTTGCTCC CAAAGAGAAA 
GGCATAACCG CCATGTCAGT GAAGGAAGTC CTTCAGAGCC TAGTGGATGA CGGTATGGTT 
GACTGCGAGA GGATCGGGAC GTCCAATTAC TATTGGGCTT TTCCGAGCAA GGCTCTTCAT 
GCCAGGAAGC GCAAGTTGGA GGCTCTGAAC TCTCAGGAAG AACGAGCCAT GCTTGCAAAA 
GAACTTTCTT CATTTCGAGA CCAAAGGCAA CAACTTAAGG CAGAAGTGGA AAAATATCGA 
GAATGTGACC CACAGGTTGT GGAAGAGATA CGTGAAGCAA ATAAAGTAGC TAAAGAAGCC 
GCCAATCGAT GGACTGATAA CATATTTGCA ATAAAATCCT GGGCCAAAAG AAAATTTGGG 
TTTGAAGAAA GTAAAATTGA TAAAAACTTT GGAATTCCAG AAGACTTTGA CTACATAGAC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006502325.1
CDS	135..677
Translation	MSKKRGLSGEEKRTRMMEIFFETKDVFQLKDLEKLAPKEKGITAMSVKEVLQSLVDDGMVDCERIGTSNYYWAFPSKALHARKRKLEALNSQEERAMLAKELSSFRDQRQQLKAEVEKYRECDPQVVEEIREANKVAKEAANRWTDNIFAIKSWAKRKFGFEESKIDKNFGIPEDFDYID

Target ORF information:

RefSeq Version	XM_006502262.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus meiotic nuclear divisions 1 (Mnd1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006502262.4

ORF Insert Sequence:

ATGTCAAAGA AAAGAGGACT GAGTGGGGAG GAAAAGAGAA CCCGGATGAT GGAGATATTT 
TTTGAGACAA AAGATGTATT CCAGCTGAAA GACCTGGAGA AGCTTGCTCC CAAAGAGAAA 
GGCATAACCG CCATGTCAGT GAAGGAAGTC CTTCAGAGCC TAGTGGATGA CGGTATGGTT 
GACTGCGAGA GGATCGGGAC GTCCAATTAC TATTGGGCTT TTCCGAGCAA GGCTCTTCAT 
GCCAGGAAGC GCAAGTTGGA GGCTCTGAAC TCTCAGGAAG AACGAGCCAT GCTTGCAAAA 
GAACTTTCTT CATTTCGAGA CCAAAGGCAA CAACTTAAGG CAGAAGTGGA AAAATATCGA 
GAATGTGACC CACAGGTTGT GGAAGAGATA CGTGAAGCAA ATAAAGTAGC TAAAGAAGCC 
GCCAATCGAT GGACTGATAA CATATTTGCA ATAAAATCCT GGGCCAAAAG AAAATTTGGG 
TTTGAAGAAA GTAAAATTGA TAAAAACTTT GGAATTCCAG AAGACTTTGA CTACATAGAC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Spatiotemporal regulation of GLI target genes in the mammalian limb bud.
Developmental biology406(1)92-103(2015 Oct)
Lewandowski JP,Du F,Zhang S,Powell MB,Falkenstein KN,Ji H,Vokes SA

Significance of ligand interactions involving Hop2-Mnd1 and the RAD51 and DMC1 recombinases in homologous DNA repair and XX ovarian dysgenesis.
Nucleic acids research43(8)4055-66(2015 Apr)
Zhao W,Sung P

HOP2-MND1 modulates RAD51 binding to nucleotides and DNA.
Nature communications54198(2014 Jun)
Bugreev DV,Huang F,Mazina OM,Pezza RJ,Voloshin ON,Camerini-Otero RD,Mazin AV

The dual role of HOP2 in mammalian meiotic homologous recombination.
Nucleic acids research42(4)2346-57(2014 Feb)
Pezza RJ,Voloshin ON,Volodin AA,Boateng KA,Bellani MA,Mazin AV,Camerini-Otero RD

Mechanistic insights into the role of Hop2-Mnd1 in meiotic homologous DNA pairing.
Nucleic acids research42(2)906-17(2014 Jan)
Zhao W,Saro D,Hammel M,Kwon Y,Xu Y,Rambo RP,Williams GJ,Chi P,Lu L,Pezza RJ,Camerini-Otero RD,Tainer JA,Wang HW,Sung P

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Mnd1 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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