Rab2b cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Rab2b
Entrez Gene ID	76338
Full Name	RAB2B, member RAS oncogene family
Synonyms	1500012D09Rik,4930528G15Rik,A230002G14,D530043M21Rik
General protein information	Preferred Names RAB2B, member RAS oncogene family Names ras-related protein Rab-2B
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 14 Map Location: 14\|14 C2

mRNA and Protein(s)

mRNA	Protein	Name
NM_172601.3	NP_766189.1	ras-related protein Rab-2B
XM_030248092.1	XP_030103952.1	ras-related protein Rab-2B isoform X1

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Rab2b	NP_001032734.1
Pan troglodytes (chimpanzee)	RAB2B	XP_003314293.1
Xenopus tropicalis (tropical clawed frog)	rab2b	NP_001005636.1
Homo sapiens (human)	RAB2B	NP_116235.2
Mus musculus (house mouse)	Rab2b	NP_766189.1
Canis lupus familiaris (dog)	RAB2B	XP_005629214.1
Bos taurus (cattle)	RAB2B	NP_001179594.1
Oryza sativa (rice)	Os04g0470100	NP_001053048.1

Gene Ontology
Bibliography

Related articles in PubMed

The RAB2B-GARIL5 Complex Promotes Cytosolic DNA-Induced Innate Immune Responses.
Takahama M, Fukuda M, Ohbayashi N, Kozaki T, Misawa T, Okamoto T, Matsuura Y, Akira S, Saitoh T
Cell reports20(12)2944-2954(2017 Sep)

Screening for target Rabs of TBC (Tre-2/Bub2/Cdc16) domain-containing proteins based on their Rab-binding activity.
Itoh T, Satoh M, Kanno E, Fukuda M
Genes to cells : devoted to molecular & cellular mechanisms11(9)1023-37(2006 Sep)

Distinct Rab binding specificity of Rim1, Rim2, rabphilin, and Noc2. Identification of a critical determinant of Rab3A/Rab27A recognition by Rim2.
Fukuda M
The Journal of biological chemistry278(17)15373-80(2003 Apr)

Slac2-a/melanophilin, the missing link between Rab27 and myosin Va: implications of a tripartite protein complex for melanosome transport.
Fukuda M, Kuroda TS, Mikoshiba K
The Journal of biological chemistry277(14)12432-6(2002 Apr)

The Slp homology domain of synaptotagmin-like proteins 1-4 and Slac2 functions as a novel Rab27A binding domain.
Kuroda TS, Fukuda M, Ariga H, Mikoshiba K
The Journal of biological chemistry277(11)9212-8(2002 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Rab2b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Rab2b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu03750	NM_172601.3 Latest version!	Mus musculus RAB2B, member RAS oncogene family (Rab2b), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
OMu86525	XM_030248092.1 Latest version!	Mus musculus RAB2B, member RAS oncogene family (Rab2b), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Rab2b ( NM_172601.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_766189.1 Mus musculus RAB2B, member RAS oncogene family (Rab2b), mRNA.

Price & Availability↑

CloneID	OMu03750
Clone ID Related Accession (Same CDS sequence)	NM_172601.3
Accession Version	NM_172601.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 651bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-22
Organism	Mus musculus(house mouse)
Product	ras-related protein Rab-2B
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY020048.1, AK038393.1 and BI732997.1. On Oct 20, 2009 this sequence version replaced NM_172601.2. ##Evidence-Data-START## Transcript exon combination :: BC046334.1, SRR1660815.60895.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849381, SAMN00849382 [ECO:0000348] ##Evidence-Data-END##

ATGACTTACG CTTATCTCTT CAAGTACATC ATCATCGGAG ACACAGGTGT GGGGAAGTCA 
TGTCTCCTCC TTCAGTTTAC CGACAAGCGG TTCCAGCCCG TGCACGACCT CACAATAGGT 
GTGGAGTTTG GAGCACGTAT GGTCAACATC GATGGAAAAC AAATCAAACT GCAAATCTGG 
GATACGGCTG GGCAAGAGTC CTTCCGTTCT ATCACCCGTT CCTACTACAG GGGAGCAGCT 
GGAGCCCTGC TGGTGTATGA CATCACGAGA CGCGAAACCT TCAACCACCT GACCTCATGG 
TTAGAGGACG CCCGCCAGCA CTCCAGCTCC AACATGGTTA TAATGCTGAT CGGGAATAAG 
AGTGATCTAG AATCTCGAAG GGATGTGAAG AGAGAGGAAG GAGAGGCCTT TGCTCGTGAG 
CACGGCCTTA TATTCATGGA AACATCAGCC AAGACAGCCT GCAATGTTGA AGAGGCCTAC 
ATTAATACAG CCAAAGAAAT ATATAGGAAG ATCCAGCAAG GTTTATTTGA TGTCCACAAT 
GAGGCAAATG GCATCAAGAT TGGGCCCCAG CAGTCAATTA CCTCCTCAGT AGGACCGTGC 
TCCCCTCAGC AGAACGTTTC TGACATAGGG CCTGACTCTG GCTGCTGCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_766189.1
CDS	155..805
Translation	MTYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMVNIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTSWLEDARQHSSSNMVIMLIGNKSDLESRRDVKREEGEAFAREHGLIFMETSAKTACNVEEAYINTAKEIYRKIQQGLFDVHNEANGIKIGPQQSITSSVGPCSPQQNVSDIGPDSGCC

Target ORF information:

RefSeq Version	NM_172601.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus RAB2B, member RAS oncogene family (Rab2b), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_172601.3

ORF Insert Sequence:

ATGACTTACG CTTATCTCTT CAAGTACATC ATCATCGGAG ACACAGGTGT GGGGAAGTCA 
TGTCTCCTCC TTCAGTTTAC CGACAAGCGG TTCCAGCCCG TGCACGACCT CACAATAGGT 
GTGGAGTTTG GAGCACGTAT GGTCAACATC GATGGAAAAC AAATCAAACT GCAAATCTGG 
GATACGGCTG GGCAAGAGTC CTTCCGTTCT ATCACCCGTT CCTACTACAG GGGAGCAGCT 
GGAGCCCTGC TGGTGTATGA CATCACGAGA CGCGAAACCT TCAACCACCT GACCTCATGG 
TTAGAGGACG CCCGCCAGCA CTCCAGCTCC AACATGGTTA TAATGCTGAT CGGGAATAAG 
AGTGATCTAG AATCTCGAAG GGATGTGAAG AGAGAGGAAG GAGAGGCCTT TGCTCGTGAG 
CACGGCCTTA TATTCATGGA AACATCAGCC AAGACAGCCT GCAATGTTGA AGAGGCCTAC 
ATTAATACAG CCAAAGAAAT ATATAGGAAG ATCCAGCAAG GTTTATTTGA TGTCCACAAT 
GAGGCAAATG GCATCAAGAT TGGGCCCCAG CAGTCAATTA CCTCCTCAGT AGGACCGTGC 
TCCCCTCAGC AGAACGTTTC TGACATAGGG CCTGACTCTG GCTGCTGCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Rab2b ( XM_030248092.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_030103952.1 Mus musculus RAB2B, member RAS oncogene family (Rab2b), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu86525
Clone ID Related Accession (Same CDS sequence)	XM_030248092.1
Accession Version	XM_030248092.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 480bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	ras-related protein Rab-2B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000080.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTTGATGG TAAAGGCTGG GCAAGAGTCC TTCCGTTCTA TCACCCGTTC CTACTACAGG 
GGAGCAGCTG GAGCCCTGCT GGTGTATGAC ATCACGAGAC GCGAAACCTT CAACCACCTG 
ACCTCATGGT TAGAGGACGC CCGCCAGCAC TCCAGCTCCA ACATGGTTAT AATGCTGATC 
GGGAATAAGA GTGATCTAGA ATCTCGAAGG GATGTGAAGA GAGAGGAAGG AGAGGCCTTT 
GCTCGTGAGC ACGGCCTTAT ATTCATGGAA ACATCAGCCA AGACAGCCTG CAATGTTGAA 
GAGGCCTACA TTAATACAGC CAAAGAAATA TATAGGAAGA TCCAGCAAGG TTTATTTGAT 
GTCCACAATG AGGCAAATGG CATCAAGATT GGGCCCCAGC AGTCAATTAC CTCCTCAGTA 
GGACCGTGCT CCCCTCAGCA GAACGTTTCT GACATAGGGC CTGACTCTGG CTGCTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_030103952.1
CDS	399..878
Translation	MLMVKAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTSWLEDARQHSSSNMVIMLIGNKSDLESRRDVKREEGEAFAREHGLIFMETSAKTACNVEEAYINTAKEIYRKIQQGLFDVHNEANGIKIGPQQSITSSVGPCSPQQNVSDIGPDSGCC

Target ORF information:

RefSeq Version	XM_030248092.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus RAB2B, member RAS oncogene family (Rab2b), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_030248092.1

ORF Insert Sequence:

ATGTTGATGG TAAAGGCTGG GCAAGAGTCC TTCCGTTCTA TCACCCGTTC CTACTACAGG 
GGAGCAGCTG GAGCCCTGCT GGTGTATGAC ATCACGAGAC GCGAAACCTT CAACCACCTG 
ACCTCATGGT TAGAGGACGC CCGCCAGCAC TCCAGCTCCA ACATGGTTAT AATGCTGATC 
GGGAATAAGA GTGATCTAGA ATCTCGAAGG GATGTGAAGA GAGAGGAAGG AGAGGCCTTT 
GCTCGTGAGC ACGGCCTTAT ATTCATGGAA ACATCAGCCA AGACAGCCTG CAATGTTGAA 
GAGGCCTACA TTAATACAGC CAAAGAAATA TATAGGAAGA TCCAGCAAGG TTTATTTGAT 
GTCCACAATG AGGCAAATGG CATCAAGATT GGGCCCCAGC AGTCAATTAC CTCCTCAGTA 
GGACCGTGCT CCCCTCAGCA GAACGTTTCT GACATAGGGC CTGACTCTGG CTGCTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The RAB2B-GARIL5 Complex Promotes Cytosolic DNA-Induced Innate Immune Responses.
Cell reports20(12)2944-2954(2017 Sep)
Takahama M,Fukuda M,Ohbayashi N,Kozaki T,Misawa T,Okamoto T,Matsuura Y,Akira S,Saitoh T

Screening for target Rabs of TBC (Tre-2/Bub2/Cdc16) domain-containing proteins based on their Rab-binding activity.
Genes to cells : devoted to molecular & cellular mechanisms11(9)1023-37(2006 Sep)
Itoh T,Satoh M,Kanno E,Fukuda M

Distinct Rab binding specificity of Rim1, Rim2, rabphilin, and Noc2. Identification of a critical determinant of Rab3A/Rab27A recognition by Rim2.
The Journal of biological chemistry278(17)15373-80(2003 Apr)
Fukuda M

Slac2-a/melanophilin, the missing link between Rab27 and myosin Va: implications of a tripartite protein complex for melanosome transport.
The Journal of biological chemistry277(14)12432-6(2002 Apr)
Fukuda M,Kuroda TS,Mikoshiba K

The Slp homology domain of synaptotagmin-like proteins 1-4 and Slac2 functions as a novel Rab27A binding domain.
The Journal of biological chemistry277(11)9212-8(2002 Mar)
Kuroda TS,Fukuda M,Ariga H,Mikoshiba K