Abcb8 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Abcb8
Entrez Gene ID	74610
Full Name	ATP-binding cassette, sub-family B (MDR/TAP), member 8
Synonyms	4833412N02Rik,AA409895
General protein information	Preferred Names ATP-binding cassette, sub-family B (MDR/TAP), member 8 Names ATP-binding cassette sub-family B member 8, mitochondrial
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 5 Map Location: 5\|5 A3

mRNA and Protein(s)

mRNA	Protein	Name
XM_011249790.2	XP_011248092.1	ATP-binding cassette sub-family B member 8, mitochondrial isoform X2
NM_029020.2	NP_083296.2	ATP-binding cassette sub-family B member 8, mitochondrial precursor
XM_006535812.1	XP_006535875.1	ATP-binding cassette sub-family B member 8, mitochondrial isoform X1
XM_011249790.3	XP_011248092.1	ATP-binding cassette sub-family B member 8, mitochondrial isoform X2
NM_029020.3	NP_083296.2	mitochondrial potassium channel ATP-binding subunit precursor

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	ABCB8	XP_519524.3
Canis lupus familiaris (dog)	ABCB8	XP_539916.2
Mus musculus (house mouse)	Abcb8	NP_083296.2
Bos taurus (cattle)	ABCB8	NP_001068994.2
Gallus gallus (chicken)	ABCB8	XP_004939090.1
Danio rerio (zebrafish)	abcb8	NP_001017544.1
Caenorhabditis elegans (roundworm)	haf-6	NP_490828.3
Drosophila melanogaster (fruit fly)	CG1824	NP_572810.1
Homo sapiens (human)	ABCB8	NP_009119.2
	ABCB8	XP_001101695.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP006273	XP_316337.4
Xenopus tropicalis (tropical clawed frog)	abcb8	NP_001121515.1
Rattus norvegicus (Norway rat)	Abcb8	NP_001007797.1

Gene Ontology
Bibliography

Related articles in PubMed

Reduction in mitochondrial iron alleviates cardiac damage during injury.
Chang HC, Wu R, Shang M, Sato T, Chen C, Shapiro JS, Liu T, Thakur A, Sawicki KT, Prasad SV, Ardehali H
EMBO molecular medicine8(3)247-67(2016 Mar)

Cardiotoxicity of doxorubicin is mediated through mitochondrial iron accumulation.
Ichikawa Y, Ghanefar M, Bayeva M, Wu R, Khechaduri A, Naga Prasad SV, Mutharasan RK, Naik TJ, Ardehali H
The Journal of clinical investigation124(2)617-30(2014 Feb)

Disruption of ATP-binding cassette B8 in mice leads to cardiomyopathy through a decrease in mitochondrial iron export.
Ichikawa Y, Bayeva M, Ghanefar M, Potini V, Sun L, Mutharasan RK, Wu R, Khechaduri A, Jairaj Naik T, Ardehali H
Proceedings of the National Academy of Sciences of the United States of America109(11)4152-7(2012 Mar)

Identification of 18 mouse ABC genes and characterization of the ABC superfamily in Mus musculus.
Schriml LM, Dean M
Genomics64(1)24-31(2000 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These results indicate that ABCB8 is essential for normal cardiac function, maintenance of mitochondrial iron homeostasis and maturation of cytosolic Fe/S proteins.
Title: Disruption of ATP-binding cassette B8 in mice leads to cardiomyopathy through a decrease in mitochondrial iron export.

The following Abcb8 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Abcb8 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu71208	XM_011249790.3 Latest version!	Mus musculus ATP-binding cassette, sub-family B (MDR/TAP), member 8 (Abcb8), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OMu21687	NM_029020.3 Latest version!	Mus musculus ATP-binding cassette, sub-family B (MDR/TAP), member 8 (Abcb8), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$391.30 $559.00
OMu21687	XM_006535812.1 Latest version!	Mus musculus ATP-binding cassette, sub-family B (MDR/TAP), member 8 (Abcb8), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$391.30 $559.00
View Old Accession Versions >>
OMu71208	XM_011249790.2	Mus musculus ATP-binding cassette, sub-family B (MDR/TAP), member 8 (Abcb8), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
OMu21687	NM_029020.2	Mus musculus ATP-binding cassette, sub-family B (MDR/TAP), member 8 (Abcb8), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$391.30 $559.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Abcb8 ( XM_011249790.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011248092.1 Mus musculus ATP-binding cassette, sub-family B (MDR/TAP), member 8 (Abcb8), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu71208
Clone ID Related Accession (Same CDS sequence)	XM_011249790.2 , XM_011249790.3
Accession Version	XM_011249790.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1344bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	ATP-binding cassette sub-family B member 8, mitochondrial isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_011249790.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTGTCCC CTCGCCTTAC CCTGATGCTG GCTGTCGTCA CACCCGCCCT CATGGGAGTG 
GGCACCCTGA TGGGCTCAGG CCTCCGAAAG CTGTCTCGCC AGTGTCAGGA GCAGATTGCC 
AGGGCAACAG GTGTAGCAGA TGAGGCCCTT GGCAATGTTC GGACTGTGCG GGCCTTCGCG 
ATGGAGAAGA GGGAGGAGGA ACGCTATCAA GCAGAACTGG AGTCATGCTG CTGTAAAGCA 
GAAGAACTGG GCAGGGGCAT CGCCTTGTTC CAAGGGCTCT CCAACATCGC TTTCAACTGT 
ATGGTCTTGG GCACCCTGTT CATTGGGGGC TCCCTTGTGG CTGGACAGCA GCTGAAAGGG 
GGAGACCTCA TGTCCTTCCT GGTGGCTTCC CAGACAGTAC AGAGGTCTAT GGCCAGCCTC 
TCTGTCCTGT TTGGTCAGGT GGTACGTGGG CTGAGTGCGG GAGCCCGAGT CTTCGAATAC 
ATGGCCCTGA GCCCTGTCAT CCCATTGACC GGGGGCTACT GCATCCCCAA CAAGGACATT 
CGTGGTTCCA TCACCTTCCA AAATGTCACC TTCAGCTACC CCTGCAGACC TGGCTTCAAT 
GTGCTCAAGG ACTTCACCCT GAAGCTGCCC TCTGGCAAGA TTGTGGCTCT TGTGGGCCAG 
TCTGGGGGAG GAAAGACCAC AGTTGCCTCC TTGCTGGAAC GCTTCTATGA CCCTGAAGCT 
GGCTCGGTGA CGTTGGATGG GCATGACCTG CGAACTCTCA ACCCCTCCTG GCTCCGGGGC 
CAGGTCATAG GTTTCATCAG CCAGGAGCCA GTCCTGTTTG CAACAACCAT CATGGAGAAT 
ATCCGATTTG GGAAGCTGGA TGCTTCCGAT GAAGAGGTGT ACACAGCTGC ACGAGAAGCC 
AATGCCCACG AGTTCATCAG CAGCTTCCCC GATGGCTACA GCACTGTGGT TGGTGAGCGG 
GGCACAACCT TGTCTGGTGG CCAGAAGCAG CGCCTAGCCA TCGCACGTGC CCTCATCAAG 
CAGCCCACAG TGCTGATCCT GGACGAGGCC ACCAGTGCGC TAGATGCAGA ATCCGAGAGG 
GTGGTACAGG AGGCCCTGGA CCGGGCCAGT GCTGGCCGCA CCGTGTTGGT CATTGCCCAC 
CGGCTTAGTA CTGTCCGTGC AGCCCACTCC ATCATTGTCA TGGCCAATGG CCAAGTCTGT 
GAGGCTGGGA CCCACGAAGA ACTCCTTAAA AAAGGCGGGC TCTATTCAGA GCTTATCCGG 
AGACAAACCC TGGACGCCTC ACTGACCTCA ACCCCTCCTG CAGAGAAGCC TGAAGACCCC 
AAAAGCTGCC AGTCCAAAGC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011248092.1
CDS	1005..2348
Translation	MLSPRLTLMLAVVTPALMGVGTLMGSGLRKLSRQCQEQIARATGVADEALGNVRTVRAFAMEKREEERYQAELESCCCKAEELGRGIALFQGLSNIAFNCMVLGTLFIGGSLVAGQQLKGGDLMSFLVASQTVQRSMASLSVLFGQVVRGLSAGARVFEYMALSPVIPLTGGYCIPNKDIRGSITFQNVTFSYPCRPGFNVLKDFTLKLPSGKIVALVGQSGGGKTTVASLLERFYDPEAGSVTLDGHDLRTLNPSWLRGQVIGFISQEPVLFATTIMENIRFGKLDASDEEVYTAAREANAHEFISSFPDGYSTVVGERGTTLSGGQKQRLAIARALIKQPTVLILDEATSALDAESERVVQEALDRASAGRTVLVIAHRLSTVRAAHSIIVMANGQVCEAGTHEELLKKGGLYSELIRRQTLDASLTSTPPAEKPEDPKSCQSKA

Target ORF information:

RefSeq Version	XM_011249790.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus ATP-binding cassette, sub-family B (MDR/TAP), member 8 (Abcb8), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011249790.2

ORF Insert Sequence:

ATGCTGTCCC CTCGCCTTAC CCTGATGCTG GCTGTCGTCA CACCCGCCCT CATGGGAGTG 
GGCACCCTGA TGGGCTCAGG CCTCCGAAAG CTGTCTCGCC AGTGTCAGGA GCAGATTGCC 
AGGGCAACAG GTGTAGCAGA TGAGGCCCTT GGCAATGTTC GGACTGTGCG GGCCTTCGCG 
ATGGAGAAGA GGGAGGAGGA ACGCTATCAA GCAGAACTGG AGTCATGCTG CTGTAAAGCA 
GAAGAACTGG GCAGGGGCAT CGCCTTGTTC CAAGGGCTCT CCAACATCGC TTTCAACTGT 
ATGGTCTTGG GCACCCTGTT CATTGGGGGC TCCCTTGTGG CTGGACAGCA GCTGAAAGGG 
GGAGACCTCA TGTCCTTCCT GGTGGCTTCC CAGACAGTAC AGAGGTCTAT GGCCAGCCTC 
TCTGTCCTGT TTGGTCAGGT GGTACGTGGG CTGAGTGCGG GAGCCCGAGT CTTCGAATAC 
ATGGCCCTGA GCCCTGTCAT CCCATTGACC GGGGGCTACT GCATCCCCAA CAAGGACATT 
CGTGGTTCCA TCACCTTCCA AAATGTCACC TTCAGCTACC CCTGCAGACC TGGCTTCAAT 
GTGCTCAAGG ACTTCACCCT GAAGCTGCCC TCTGGCAAGA TTGTGGCTCT TGTGGGCCAG 
TCTGGGGGAG GAAAGACCAC AGTTGCCTCC TTGCTGGAAC GCTTCTATGA CCCTGAAGCT 
GGCTCGGTGA CGTTGGATGG GCATGACCTG CGAACTCTCA ACCCCTCCTG GCTCCGGGGC 
CAGGTCATAG GTTTCATCAG CCAGGAGCCA GTCCTGTTTG CAACAACCAT CATGGAGAAT 
ATCCGATTTG GGAAGCTGGA TGCTTCCGAT GAAGAGGTGT ACACAGCTGC ACGAGAAGCC 
AATGCCCACG AGTTCATCAG CAGCTTCCCC GATGGCTACA GCACTGTGGT TGGTGAGCGG 
GGCACAACCT TGTCTGGTGG CCAGAAGCAG CGCCTAGCCA TCGCACGTGC CCTCATCAAG 
CAGCCCACAG TGCTGATCCT GGACGAGGCC ACCAGTGCGC TAGATGCAGA ATCCGAGAGG 
GTGGTACAGG AGGCCCTGGA CCGGGCCAGT GCTGGCCGCA CCGTGTTGGT CATTGCCCAC 
CGGCTTAGTA CTGTCCGTGC AGCCCACTCC ATCATTGTCA TGGCCAATGG CCAAGTCTGT 
GAGGCTGGGA CCCACGAAGA ACTCCTTAAA AAAGGCGGGC TCTATTCAGA GCTTATCCGG 
AGACAAACCC TGGACGCCTC ACTGACCTCA ACCCCTCCTG CAGAGAAGCC TGAAGACCCC 
AAAAGCTGCC AGTCCAAAGC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Abcb8 ( XM_011249790.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011248092.1 Mus musculus ATP-binding cassette, sub-family B (MDR/TAP), member 8 (Abcb8), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu71208
Clone ID Related Accession (Same CDS sequence)	XM_011249790.2 , XM_011249790.3
Accession Version	XM_011249790.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1344bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	ATP-binding cassette sub-family B member 8, mitochondrial isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_011249790.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTGTCCC CTCGCCTTAC CCTGATGCTG GCTGTCGTCA CACCCGCCCT CATGGGAGTG 
GGCACCCTGA TGGGCTCAGG CCTCCGAAAG CTGTCTCGCC AGTGTCAGGA GCAGATTGCC 
AGGGCAACAG GTGTAGCAGA TGAGGCCCTT GGCAATGTTC GGACTGTGCG GGCCTTCGCG 
ATGGAGAAGA GGGAGGAGGA ACGCTATCAA GCAGAACTGG AGTCATGCTG CTGTAAAGCA 
GAAGAACTGG GCAGGGGCAT CGCCTTGTTC CAAGGGCTCT CCAACATCGC TTTCAACTGT 
ATGGTCTTGG GCACCCTGTT CATTGGGGGC TCCCTTGTGG CTGGACAGCA GCTGAAAGGG 
GGAGACCTCA TGTCCTTCCT GGTGGCTTCC CAGACAGTAC AGAGGTCTAT GGCCAGCCTC 
TCTGTCCTGT TTGGTCAGGT GGTACGTGGG CTGAGTGCGG GAGCCCGAGT CTTCGAATAC 
ATGGCCCTGA GCCCTGTCAT CCCATTGACC GGGGGCTACT GCATCCCCAA CAAGGACATT 
CGTGGTTCCA TCACCTTCCA AAATGTCACC TTCAGCTACC CCTGCAGACC TGGCTTCAAT 
GTGCTCAAGG ACTTCACCCT GAAGCTGCCC TCTGGCAAGA TTGTGGCTCT TGTGGGCCAG 
TCTGGGGGAG GAAAGACCAC AGTTGCCTCC TTGCTGGAAC GCTTCTATGA CCCTGAAGCT 
GGCTCGGTGA CGTTGGATGG GCATGACCTG CGAACTCTCA ACCCCTCCTG GCTCCGGGGC 
CAGGTCATAG GTTTCATCAG CCAGGAGCCA GTCCTGTTTG CAACAACCAT CATGGAGAAT 
ATCCGATTTG GGAAGCTGGA TGCTTCCGAT GAAGAGGTGT ACACAGCTGC ACGAGAAGCC 
AATGCCCACG AGTTCATCAG CAGCTTCCCC GATGGCTACA GCACTGTGGT TGGTGAGCGG 
GGCACAACCT TGTCTGGTGG CCAGAAGCAG CGCCTAGCCA TCGCACGTGC CCTCATCAAG 
CAGCCCACAG TGCTGATCCT GGACGAGGCC ACCAGTGCGC TAGATGCAGA ATCCGAGAGG 
GTGGTACAGG AGGCCCTGGA CCGGGCCAGT GCTGGCCGCA CCGTGTTGGT CATTGCCCAC 
CGGCTTAGTA CTGTCCGTGC AGCCCACTCC ATCATTGTCA TGGCCAATGG CCAAGTCTGT 
GAGGCTGGGA CCCACGAAGA ACTCCTTAAA AAAGGCGGGC TCTATTCAGA GCTTATCCGG 
AGACAAACCC TGGACGCCTC ACTGACCTCA ACCCCTCCTG CAGAGAAGCC TGAAGACCCC 
AAAAGCTGCC AGTCCAAAGC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011248092.1
CDS	1114..2457
Translation	MLSPRLTLMLAVVTPALMGVGTLMGSGLRKLSRQCQEQIARATGVADEALGNVRTVRAFAMEKREEERYQAELESCCCKAEELGRGIALFQGLSNIAFNCMVLGTLFIGGSLVAGQQLKGGDLMSFLVASQTVQRSMASLSVLFGQVVRGLSAGARVFEYMALSPVIPLTGGYCIPNKDIRGSITFQNVTFSYPCRPGFNVLKDFTLKLPSGKIVALVGQSGGGKTTVASLLERFYDPEAGSVTLDGHDLRTLNPSWLRGQVIGFISQEPVLFATTIMENIRFGKLDASDEEVYTAAREANAHEFISSFPDGYSTVVGERGTTLSGGQKQRLAIARALIKQPTVLILDEATSALDAESERVVQEALDRASAGRTVLVIAHRLSTVRAAHSIIVMANGQVCEAGTHEELLKKGGLYSELIRRQTLDASLTSTPPAEKPEDPKSCQSKA

Target ORF information:

RefSeq Version	XM_011249790.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus ATP-binding cassette, sub-family B (MDR/TAP), member 8 (Abcb8), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011249790.3

ORF Insert Sequence:

ATGCTGTCCC CTCGCCTTAC CCTGATGCTG GCTGTCGTCA CACCCGCCCT CATGGGAGTG 
GGCACCCTGA TGGGCTCAGG CCTCCGAAAG CTGTCTCGCC AGTGTCAGGA GCAGATTGCC 
AGGGCAACAG GTGTAGCAGA TGAGGCCCTT GGCAATGTTC GGACTGTGCG GGCCTTCGCG 
ATGGAGAAGA GGGAGGAGGA ACGCTATCAA GCAGAACTGG AGTCATGCTG CTGTAAAGCA 
GAAGAACTGG GCAGGGGCAT CGCCTTGTTC CAAGGGCTCT CCAACATCGC TTTCAACTGT 
ATGGTCTTGG GCACCCTGTT CATTGGGGGC TCCCTTGTGG CTGGACAGCA GCTGAAAGGG 
GGAGACCTCA TGTCCTTCCT GGTGGCTTCC CAGACAGTAC AGAGGTCTAT GGCCAGCCTC 
TCTGTCCTGT TTGGTCAGGT GGTACGTGGG CTGAGTGCGG GAGCCCGAGT CTTCGAATAC 
ATGGCCCTGA GCCCTGTCAT CCCATTGACC GGGGGCTACT GCATCCCCAA CAAGGACATT 
CGTGGTTCCA TCACCTTCCA AAATGTCACC TTCAGCTACC CCTGCAGACC TGGCTTCAAT 
GTGCTCAAGG ACTTCACCCT GAAGCTGCCC TCTGGCAAGA TTGTGGCTCT TGTGGGCCAG 
TCTGGGGGAG GAAAGACCAC AGTTGCCTCC TTGCTGGAAC GCTTCTATGA CCCTGAAGCT 
GGCTCGGTGA CGTTGGATGG GCATGACCTG CGAACTCTCA ACCCCTCCTG GCTCCGGGGC 
CAGGTCATAG GTTTCATCAG CCAGGAGCCA GTCCTGTTTG CAACAACCAT CATGGAGAAT 
ATCCGATTTG GGAAGCTGGA TGCTTCCGAT GAAGAGGTGT ACACAGCTGC ACGAGAAGCC 
AATGCCCACG AGTTCATCAG CAGCTTCCCC GATGGCTACA GCACTGTGGT TGGTGAGCGG 
GGCACAACCT TGTCTGGTGG CCAGAAGCAG CGCCTAGCCA TCGCACGTGC CCTCATCAAG 
CAGCCCACAG TGCTGATCCT GGACGAGGCC ACCAGTGCGC TAGATGCAGA ATCCGAGAGG 
GTGGTACAGG AGGCCCTGGA CCGGGCCAGT GCTGGCCGCA CCGTGTTGGT CATTGCCCAC 
CGGCTTAGTA CTGTCCGTGC AGCCCACTCC ATCATTGTCA TGGCCAATGG CCAAGTCTGT 
GAGGCTGGGA CCCACGAAGA ACTCCTTAAA AAAGGCGGGC TCTATTCAGA GCTTATCCGG 
AGACAAACCC TGGACGCCTC ACTGACCTCA ACCCCTCCTG CAGAGAAGCC TGAAGACCCC 
AAAAGCTGCC AGTCCAAAGC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Abcb8 ( NM_029020.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_083296.2 Mus musculus ATP-binding cassette, sub-family B (MDR/TAP), member 8 (Abcb8), mRNA.

Price & Availability↑

CloneID	OMu21687
Clone ID Related Accession (Same CDS sequence)	NM_029020.2 , XM_006535812.1 , NM_029020.3
Accession Version	NM_029020.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2154bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-28
Organism	Mus musculus(house mouse)
Product	ATP-binding cassette sub-family B member 8, mitochondrial precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC015301.1. On Jan 15, 2003 this sequence version replaced NM_029020.1. ##Evidence-Data-START## Transcript exon combination :: BC015301.1, AK076315.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END##

ATGTTGGTGC ACTTATTTCG GTTCGGAATC CGGGGTGGCC CAGTTCCAGG ATGGTCGCTA 
CAATCCCTGC GCTTCCAGAC GTTCTCTGCC GCCAGGTCCT CAGATGACCG GCTCAGCTCA 
CACCTCCTGC GGACTGTAGC CCAGCTCCGT GTACAGCTCC GGGCTCACCT CCCTCGAGCC 
CCACCAGCTT CCCACTGGAG CCCCTCTGCC TGGTGTTGGG TTGGGGGGAC CTTGGTGGTC 
CCTGCAGTCC TGTGGCAGCA TCCACGCCTC TGCCTTATAG CACTATGTGA GGCCAAAGAG 
TCCCCTCCTG CCCAGCCCAC ACGTGCCCCA GAGCTGCGCT TTAATTGGAA GCTCTTCTGG 
CATTTCCTTC ACCCCCACCT GCTGGCCTTG GGGGCAGCCA TTGTGCTGGC CTTAGGTGCG 
GCACTAGTGA ATGTGCAGAT CCCCTTGCTC CTGGGCCAGC TGGTGGAGAT TGTCGCCAAG 
TACACGAGGG ACCACATGGG GAGTTTCGTG TCTGAGTCCC GTAAGCTCAG CGTCCAGCTG 
CTCCTACTGT ACGGTGTTCA GGGACTGCTG ACCTTTGGAT ACCTAGTGCT GCTGTCCCAC 
ATTGGTGAGC GCATGGCCAT GGACATGCGG AAAGCCCTTT TCAGCTCCCT GCTCCGGCAA 
GACATTGCTT TCTTTGATGC CAAAAAGACA GGGCAGCTAG TGAGTCGCTT GACTACTGAT 
GTGCAAGAAT TCAAGTCATC CTTCAAGCTT GTCATCTCCC AGGGACTGCG CAGCTGCACC 
CAGGTGATTG GTAGCCTGGT GTCCCTGTCT ATGCTGTCCC CTCGCCTTAC CCTGATGCTG 
GCTGTCGTCA CACCCGCCCT CATGGGAGTG GGCACCCTGA TGGGCTCAGG CCTCCGAAAG 
CTGTCTCGCC AGTGTCAGGA GCAGATTGCC AGGGCAACAG GTGTAGCAGA TGAGGCCCTT 
GGCAATGTTC GGACTGTGCG GGCCTTCGCG ATGGAGAAGA GGGAGGAGGA ACGCTATCAA 
GCAGAACTGG AGTCATGCTG CTGTAAAGCA GAAGAACTGG GCAGGGGCAT CGCCTTGTTC 
CAAGGGCTCT CCAACATCGC TTTCAACTGT ATGGTCTTGG GCACCCTGTT CATTGGGGGC 
TCCCTTGTGG CTGGACAGCA GCTGAAAGGG GGAGACCTCA TGTCCTTCCT GGTGGCTTCC 
CAGACAGTAC AGAGGTCTAT GGCCAGCCTC TCTGTCCTGT TTGGTCAGGT GGTACGTGGG 
CTGAGTGCGG GAGCCCGAGT CTTCGAATAC ATGGCCCTGA GCCCTGTCAT CCCATTGACC 
GGGGGCTACT GCATCCCCAA CAAGGACATT CGTGGTTCCA TCACCTTCCA AAATGTCACC 
TTCAGCTACC CCTGCAGACC TGGCTTCAAT GTGCTCAAGG ACTTCACCCT GAAGCTGCCC 
TCTGGCAAGA TTGTGGCTCT TGTGGGCCAG TCTGGGGGAG GAAAGACCAC AGTTGCCTCC 
TTGCTGGAAC GCTTCTATGA CCCTGAAGCT GGCTCGGTGA CGTTGGATGG GCATGACCTG 
CGAACTCTCA ACCCCTCCTG GCTCCGGGGC CAGGTCATAG GTTTCATCAG CCAGGAGCCA 
GTCCTGTTTG CAACAACCAT CATGGAGAAT ATCCGATTTG GGAAGCTGGA TGCTTCCGAT 
GAAGAGGTGT ACACAGCTGC ACGAGAAGCC AATGCCCACG AGTTCATCAG CAGCTTCCCC 
GATGGCTACA GCACTGTGGT TGGTGAGCGG GGCACAACCT TGTCTGGTGG CCAGAAGCAG 
CGCCTAGCCA TCGCACGTGC CCTCATCAAG CAGCCCACAG TGCTGATCCT GGACGAGGCC 
ACCAGTGCGC TAGATGCAGA ATCCGAGAGG GTGGTACAGG AGGCCCTGGA CCGGGCCAGT 
GCTGGCCGCA CCGTGTTGGT CATTGCCCAC CGGCTTAGTA CTGTCCGTGC AGCCCACTCC 
ATCATTGTCA TGGCCAATGG CCAAGTCTGT GAGGCTGGGA CCCACGAAGA ACTCCTTAAA 
AAAGGCGGGC TCTATTCAGA GCTTATCCGG AGACAAACCC TGGACGCCTC ACTGACCTCA 
ACCCCTCCTG CAGAGAAGCC TGAAGACCCC AAAAGCTGCC AGTCCAAAGC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_083296.2
CDS	341..2494
Translation	MLVHLFRFGIRGGPVPGWSLQSLRFQTFSAARSSDDRLSSHLLRTVAQLRVQLRAHLPRAPPASHWSPSAWCWVGGTLVVPAVLWQHPRLCLIALCEAKESPPAQPTRAPELRFNWKLFWHFLHPHLLALGAAIVLALGAALVNVQIPLLLGQLVEIVAKYTRDHMGSFVSESRKLSVQLLLLYGVQGLLTFGYLVLLSHIGERMAMDMRKALFSSLLRQDIAFFDAKKTGQLVSRLTTDVQEFKSSFKLVISQGLRSCTQVIGSLVSLSMLSPRLTLMLAVVTPALMGVGTLMGSGLRKLSRQCQEQIARATGVADEALGNVRTVRAFAMEKREEERYQAELESCCCKAEELGRGIALFQGLSNIAFNCMVLGTLFIGGSLVAGQQLKGGDLMSFLVASQTVQRSMASLSVLFGQVVRGLSAGARVFEYMALSPVIPLTGGYCIPNKDIRGSITFQNVTFSYPCRPGFNVLKDFTLKLPSGKIVALVGQSGGGKTTVASLLERFYDPEAGSVTLDGHDLRTLNPSWLRGQVIGFISQEPVLFATTIMENIRFGKLDASDEEVYTAAREANAHEFISSFPDGYSTVVGERGTTLSGGQKQRLAIARALIKQPTVLILDEATSALDAESERVVQEALDRASAGRTVLVIAHRLSTVRAAHSIIVMANGQVCEAGTHEELLKKGGLYSELIRRQTLDASLTSTPPAEKPEDPKSCQSKA

Target ORF information:

RefSeq Version	NM_029020.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus ATP-binding cassette, sub-family B (MDR/TAP), member 8 (Abcb8), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_029020.2

ORF Insert Sequence:

ATGTTGGTGC ACTTATTTCG GTTCGGAATC CGGGGTGGCC CAGTTCCAGG ATGGTCGCTA 
CAATCCCTGC GCTTCCAGAC GTTCTCTGCC GCCAGGTCCT CAGATGACCG GCTCAGCTCA 
CACCTCCTGC GGACTGTAGC CCAGCTCCGT GTACAGCTCC GGGCTCACCT CCCTCGAGCC 
CCACCAGCTT CCCACTGGAG CCCCTCTGCC TGGTGTTGGG TTGGGGGGAC CTTGGTGGTC 
CCTGCAGTCC TGTGGCAGCA TCCACGCCTC TGCCTTATAG CACTATGTGA GGCCAAAGAG 
TCCCCTCCTG CCCAGCCCAC ACGTGCCCCA GAGCTGCGCT TTAATTGGAA GCTCTTCTGG 
CATTTCCTTC ACCCCCACCT GCTGGCCTTG GGGGCAGCCA TTGTGCTGGC CTTAGGTGCG 
GCACTAGTGA ATGTGCAGAT CCCCTTGCTC CTGGGCCAGC TGGTGGAGAT TGTCGCCAAG 
TACACGAGGG ACCACATGGG GAGTTTCGTG TCTGAGTCCC GTAAGCTCAG CGTCCAGCTG 
CTCCTACTGT ACGGTGTTCA GGGACTGCTG ACCTTTGGAT ACCTAGTGCT GCTGTCCCAC 
ATTGGTGAGC GCATGGCCAT GGACATGCGG AAAGCCCTTT TCAGCTCCCT GCTCCGGCAA 
GACATTGCTT TCTTTGATGC CAAAAAGACA GGGCAGCTAG TGAGTCGCTT GACTACTGAT 
GTGCAAGAAT TCAAGTCATC CTTCAAGCTT GTCATCTCCC AGGGACTGCG CAGCTGCACC 
CAGGTGATTG GTAGCCTGGT GTCCCTGTCT ATGCTGTCCC CTCGCCTTAC CCTGATGCTG 
GCTGTCGTCA CACCCGCCCT CATGGGAGTG GGCACCCTGA TGGGCTCAGG CCTCCGAAAG 
CTGTCTCGCC AGTGTCAGGA GCAGATTGCC AGGGCAACAG GTGTAGCAGA TGAGGCCCTT 
GGCAATGTTC GGACTGTGCG GGCCTTCGCG ATGGAGAAGA GGGAGGAGGA ACGCTATCAA 
GCAGAACTGG AGTCATGCTG CTGTAAAGCA GAAGAACTGG GCAGGGGCAT CGCCTTGTTC 
CAAGGGCTCT CCAACATCGC TTTCAACTGT ATGGTCTTGG GCACCCTGTT CATTGGGGGC 
TCCCTTGTGG CTGGACAGCA GCTGAAAGGG GGAGACCTCA TGTCCTTCCT GGTGGCTTCC 
CAGACAGTAC AGAGGTCTAT GGCCAGCCTC TCTGTCCTGT TTGGTCAGGT GGTACGTGGG 
CTGAGTGCGG GAGCCCGAGT CTTCGAATAC ATGGCCCTGA GCCCTGTCAT CCCATTGACC 
GGGGGCTACT GCATCCCCAA CAAGGACATT CGTGGTTCCA TCACCTTCCA AAATGTCACC 
TTCAGCTACC CCTGCAGACC TGGCTTCAAT GTGCTCAAGG ACTTCACCCT GAAGCTGCCC 
TCTGGCAAGA TTGTGGCTCT TGTGGGCCAG TCTGGGGGAG GAAAGACCAC AGTTGCCTCC 
TTGCTGGAAC GCTTCTATGA CCCTGAAGCT GGCTCGGTGA CGTTGGATGG GCATGACCTG 
CGAACTCTCA ACCCCTCCTG GCTCCGGGGC CAGGTCATAG GTTTCATCAG CCAGGAGCCA 
GTCCTGTTTG CAACAACCAT CATGGAGAAT ATCCGATTTG GGAAGCTGGA TGCTTCCGAT 
GAAGAGGTGT ACACAGCTGC ACGAGAAGCC AATGCCCACG AGTTCATCAG CAGCTTCCCC 
GATGGCTACA GCACTGTGGT TGGTGAGCGG GGCACAACCT TGTCTGGTGG CCAGAAGCAG 
CGCCTAGCCA TCGCACGTGC CCTCATCAAG CAGCCCACAG TGCTGATCCT GGACGAGGCC 
ACCAGTGCGC TAGATGCAGA ATCCGAGAGG GTGGTACAGG AGGCCCTGGA CCGGGCCAGT 
GCTGGCCGCA CCGTGTTGGT CATTGCCCAC CGGCTTAGTA CTGTCCGTGC AGCCCACTCC 
ATCATTGTCA TGGCCAATGG CCAAGTCTGT GAGGCTGGGA CCCACGAAGA ACTCCTTAAA 
AAAGGCGGGC TCTATTCAGA GCTTATCCGG AGACAAACCC TGGACGCCTC ACTGACCTCA 
ACCCCTCCTG CAGAGAAGCC TGAAGACCCC AAAAGCTGCC AGTCCAAAGC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Abcb8 ( NM_029020.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_083296.2 Mus musculus ATP-binding cassette, sub-family B (MDR/TAP), member 8 (Abcb8), mRNA.

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CloneID	OMu21687
Clone ID Related Accession (Same CDS sequence)	NM_029020.2 , XM_006535812.1 , NM_029020.3
Accession Version	NM_029020.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2154bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-16
Organism	Mus musculus(house mouse)
Product	mitochondrial potassium channel ATP-binding subunit precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC113055.9. On Aug 16, 2018 this sequence version replaced NM_029020.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: BC015301.1, SRR7345562.1321161.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END##

ATGTTGGTGC ACTTATTTCG GTTCGGAATC CGGGGTGGCC CAGTTCCAGG ATGGTCGCTA 
CAATCCCTGC GCTTCCAGAC GTTCTCTGCC GCCAGGTCCT CAGATGACCG GCTCAGCTCA 
CACCTCCTGC GGACTGTAGC CCAGCTCCGT GTACAGCTCC GGGCTCACCT CCCTCGAGCC 
CCACCAGCTT CCCACTGGAG CCCCTCTGCC TGGTGTTGGG TTGGGGGGAC CTTGGTGGTC 
CCTGCAGTCC TGTGGCAGCA TCCACGCCTC TGCCTTATAG CACTATGTGA GGCCAAAGAG 
TCCCCTCCTG CCCAGCCCAC ACGTGCCCCA GAGCTGCGCT TTAATTGGAA GCTCTTCTGG 
CATTTCCTTC ACCCCCACCT GCTGGCCTTG GGGGCAGCCA TTGTGCTGGC CTTAGGTGCG 
GCACTAGTGA ATGTGCAGAT CCCCTTGCTC CTGGGCCAGC TGGTGGAGAT TGTCGCCAAG 
TACACGAGGG ACCACATGGG GAGTTTCGTG TCTGAGTCCC GTAAGCTCAG CGTCCAGCTG 
CTCCTACTGT ACGGTGTTCA GGGACTGCTG ACCTTTGGAT ACCTAGTGCT GCTGTCCCAC 
ATTGGTGAGC GCATGGCCAT GGACATGCGG AAAGCCCTTT TCAGCTCCCT GCTCCGGCAA 
GACATTGCTT TCTTTGATGC CAAAAAGACA GGGCAGCTAG TGAGTCGCTT GACTACTGAT 
GTGCAAGAAT TCAAGTCATC CTTCAAGCTT GTCATCTCCC AGGGACTGCG CAGCTGCACC 
CAGGTGATTG GTAGCCTGGT GTCCCTGTCT ATGCTGTCCC CTCGCCTTAC CCTGATGCTG 
GCTGTCGTCA CACCCGCCCT CATGGGAGTG GGCACCCTGA TGGGCTCAGG CCTCCGAAAG 
CTGTCTCGCC AGTGTCAGGA GCAGATTGCC AGGGCAACAG GTGTAGCAGA TGAGGCCCTT 
GGCAATGTTC GGACTGTGCG GGCCTTCGCG ATGGAGAAGA GGGAGGAGGA ACGCTATCAA 
GCAGAACTGG AGTCATGCTG CTGTAAAGCA GAAGAACTGG GCAGGGGCAT CGCCTTGTTC 
CAAGGGCTCT CCAACATCGC TTTCAACTGT ATGGTCTTGG GCACCCTGTT CATTGGGGGC 
TCCCTTGTGG CTGGACAGCA GCTGAAAGGG GGAGACCTCA TGTCCTTCCT GGTGGCTTCC 
CAGACAGTAC AGAGGTCTAT GGCCAGCCTC TCTGTCCTGT TTGGTCAGGT GGTACGTGGG 
CTGAGTGCGG GAGCCCGAGT CTTCGAATAC ATGGCCCTGA GCCCTGTCAT CCCATTGACC 
GGGGGCTACT GCATCCCCAA CAAGGACATT CGTGGTTCCA TCACCTTCCA AAATGTCACC 
TTCAGCTACC CCTGCAGACC TGGCTTCAAT GTGCTCAAGG ACTTCACCCT GAAGCTGCCC 
TCTGGCAAGA TTGTGGCTCT TGTGGGCCAG TCTGGGGGAG GAAAGACCAC AGTTGCCTCC 
TTGCTGGAAC GCTTCTATGA CCCTGAAGCT GGCTCGGTGA CGTTGGATGG GCATGACCTG 
CGAACTCTCA ACCCCTCCTG GCTCCGGGGC CAGGTCATAG GTTTCATCAG CCAGGAGCCA 
GTCCTGTTTG CAACAACCAT CATGGAGAAT ATCCGATTTG GGAAGCTGGA TGCTTCCGAT 
GAAGAGGTGT ACACAGCTGC ACGAGAAGCC AATGCCCACG AGTTCATCAG CAGCTTCCCC 
GATGGCTACA GCACTGTGGT TGGTGAGCGG GGCACAACCT TGTCTGGTGG CCAGAAGCAG 
CGCCTAGCCA TCGCACGTGC CCTCATCAAG CAGCCCACAG TGCTGATCCT GGACGAGGCC 
ACCAGTGCGC TAGATGCAGA ATCCGAGAGG GTGGTACAGG AGGCCCTGGA CCGGGCCAGT 
GCTGGCCGCA CCGTGTTGGT CATTGCCCAC CGGCTTAGTA CTGTCCGTGC AGCCCACTCC 
ATCATTGTCA TGGCCAATGG CCAAGTCTGT GAGGCTGGGA CCCACGAAGA ACTCCTTAAA 
AAAGGCGGGC TCTATTCAGA GCTTATCCGG AGACAAACCC TGGACGCCTC ACTGACCTCA 
ACCCCTCCTG CAGAGAAGCC TGAAGACCCC AAAAGCTGCC AGTCCAAAGC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_083296.2
CDS	334..2487
Translation	MLVHLFRFGIRGGPVPGWSLQSLRFQTFSAARSSDDRLSSHLLRTVAQLRVQLRAHLPRAPPASHWSPSAWCWVGGTLVVPAVLWQHPRLCLIALCEAKESPPAQPTRAPELRFNWKLFWHFLHPHLLALGAAIVLALGAALVNVQIPLLLGQLVEIVAKYTRDHMGSFVSESRKLSVQLLLLYGVQGLLTFGYLVLLSHIGERMAMDMRKALFSSLLRQDIAFFDAKKTGQLVSRLTTDVQEFKSSFKLVISQGLRSCTQVIGSLVSLSMLSPRLTLMLAVVTPALMGVGTLMGSGLRKLSRQCQEQIARATGVADEALGNVRTVRAFAMEKREEERYQAELESCCCKAEELGRGIALFQGLSNIAFNCMVLGTLFIGGSLVAGQQLKGGDLMSFLVASQTVQRSMASLSVLFGQVVRGLSAGARVFEYMALSPVIPLTGGYCIPNKDIRGSITFQNVTFSYPCRPGFNVLKDFTLKLPSGKIVALVGQSGGGKTTVASLLERFYDPEAGSVTLDGHDLRTLNPSWLRGQVIGFISQEPVLFATTIMENIRFGKLDASDEEVYTAAREANAHEFISSFPDGYSTVVGERGTTLSGGQKQRLAIARALIKQPTVLILDEATSALDAESERVVQEALDRASAGRTVLVIAHRLSTVRAAHSIIVMANGQVCEAGTHEELLKKGGLYSELIRRQTLDASLTSTPPAEKPEDPKSCQSKA

Target ORF information:

RefSeq Version	NM_029020.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus ATP-binding cassette, sub-family B (MDR/TAP), member 8 (Abcb8), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_029020.3

ORF Insert Sequence:

ATGTTGGTGC ACTTATTTCG GTTCGGAATC CGGGGTGGCC CAGTTCCAGG ATGGTCGCTA 
CAATCCCTGC GCTTCCAGAC GTTCTCTGCC GCCAGGTCCT CAGATGACCG GCTCAGCTCA 
CACCTCCTGC GGACTGTAGC CCAGCTCCGT GTACAGCTCC GGGCTCACCT CCCTCGAGCC 
CCACCAGCTT CCCACTGGAG CCCCTCTGCC TGGTGTTGGG TTGGGGGGAC CTTGGTGGTC 
CCTGCAGTCC TGTGGCAGCA TCCACGCCTC TGCCTTATAG CACTATGTGA GGCCAAAGAG 
TCCCCTCCTG CCCAGCCCAC ACGTGCCCCA GAGCTGCGCT TTAATTGGAA GCTCTTCTGG 
CATTTCCTTC ACCCCCACCT GCTGGCCTTG GGGGCAGCCA TTGTGCTGGC CTTAGGTGCG 
GCACTAGTGA ATGTGCAGAT CCCCTTGCTC CTGGGCCAGC TGGTGGAGAT TGTCGCCAAG 
TACACGAGGG ACCACATGGG GAGTTTCGTG TCTGAGTCCC GTAAGCTCAG CGTCCAGCTG 
CTCCTACTGT ACGGTGTTCA GGGACTGCTG ACCTTTGGAT ACCTAGTGCT GCTGTCCCAC 
ATTGGTGAGC GCATGGCCAT GGACATGCGG AAAGCCCTTT TCAGCTCCCT GCTCCGGCAA 
GACATTGCTT TCTTTGATGC CAAAAAGACA GGGCAGCTAG TGAGTCGCTT GACTACTGAT 
GTGCAAGAAT TCAAGTCATC CTTCAAGCTT GTCATCTCCC AGGGACTGCG CAGCTGCACC 
CAGGTGATTG GTAGCCTGGT GTCCCTGTCT ATGCTGTCCC CTCGCCTTAC CCTGATGCTG 
GCTGTCGTCA CACCCGCCCT CATGGGAGTG GGCACCCTGA TGGGCTCAGG CCTCCGAAAG 
CTGTCTCGCC AGTGTCAGGA GCAGATTGCC AGGGCAACAG GTGTAGCAGA TGAGGCCCTT 
GGCAATGTTC GGACTGTGCG GGCCTTCGCG ATGGAGAAGA GGGAGGAGGA ACGCTATCAA 
GCAGAACTGG AGTCATGCTG CTGTAAAGCA GAAGAACTGG GCAGGGGCAT CGCCTTGTTC 
CAAGGGCTCT CCAACATCGC TTTCAACTGT ATGGTCTTGG GCACCCTGTT CATTGGGGGC 
TCCCTTGTGG CTGGACAGCA GCTGAAAGGG GGAGACCTCA TGTCCTTCCT GGTGGCTTCC 
CAGACAGTAC AGAGGTCTAT GGCCAGCCTC TCTGTCCTGT TTGGTCAGGT GGTACGTGGG 
CTGAGTGCGG GAGCCCGAGT CTTCGAATAC ATGGCCCTGA GCCCTGTCAT CCCATTGACC 
GGGGGCTACT GCATCCCCAA CAAGGACATT CGTGGTTCCA TCACCTTCCA AAATGTCACC 
TTCAGCTACC CCTGCAGACC TGGCTTCAAT GTGCTCAAGG ACTTCACCCT GAAGCTGCCC 
TCTGGCAAGA TTGTGGCTCT TGTGGGCCAG TCTGGGGGAG GAAAGACCAC AGTTGCCTCC 
TTGCTGGAAC GCTTCTATGA CCCTGAAGCT GGCTCGGTGA CGTTGGATGG GCATGACCTG 
CGAACTCTCA ACCCCTCCTG GCTCCGGGGC CAGGTCATAG GTTTCATCAG CCAGGAGCCA 
GTCCTGTTTG CAACAACCAT CATGGAGAAT ATCCGATTTG GGAAGCTGGA TGCTTCCGAT 
GAAGAGGTGT ACACAGCTGC ACGAGAAGCC AATGCCCACG AGTTCATCAG CAGCTTCCCC 
GATGGCTACA GCACTGTGGT TGGTGAGCGG GGCACAACCT TGTCTGGTGG CCAGAAGCAG 
CGCCTAGCCA TCGCACGTGC CCTCATCAAG CAGCCCACAG TGCTGATCCT GGACGAGGCC 
ACCAGTGCGC TAGATGCAGA ATCCGAGAGG GTGGTACAGG AGGCCCTGGA CCGGGCCAGT 
GCTGGCCGCA CCGTGTTGGT CATTGCCCAC CGGCTTAGTA CTGTCCGTGC AGCCCACTCC 
ATCATTGTCA TGGCCAATGG CCAAGTCTGT GAGGCTGGGA CCCACGAAGA ACTCCTTAAA 
AAAGGCGGGC TCTATTCAGA GCTTATCCGG AGACAAACCC TGGACGCCTC ACTGACCTCA 
ACCCCTCCTG CAGAGAAGCC TGAAGACCCC AAAAGCTGCC AGTCCAAAGC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Abcb8 ( XM_006535812.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006535875.1 Mus musculus ATP-binding cassette, sub-family B (MDR/TAP), member 8 (Abcb8), transcript variant X1, mRNA.

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CloneID	OMu21687
Clone ID Related Accession (Same CDS sequence)	NM_029020.2 , XM_006535812.1 , NM_029020.3
Accession Version	XM_006535812.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2154bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	ATP-binding cassette sub-family B member 8, mitochondrial isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTTGGTGC ACTTATTTCG GTTCGGAATC CGGGGTGGCC CAGTTCCAGG ATGGTCGCTA 
CAATCCCTGC GCTTCCAGAC GTTCTCTGCC GCCAGGTCCT CAGATGACCG GCTCAGCTCA 
CACCTCCTGC GGACTGTAGC CCAGCTCCGT GTACAGCTCC GGGCTCACCT CCCTCGAGCC 
CCACCAGCTT CCCACTGGAG CCCCTCTGCC TGGTGTTGGG TTGGGGGGAC CTTGGTGGTC 
CCTGCAGTCC TGTGGCAGCA TCCACGCCTC TGCCTTATAG CACTATGTGA GGCCAAAGAG 
TCCCCTCCTG CCCAGCCCAC ACGTGCCCCA GAGCTGCGCT TTAATTGGAA GCTCTTCTGG 
CATTTCCTTC ACCCCCACCT GCTGGCCTTG GGGGCAGCCA TTGTGCTGGC CTTAGGTGCG 
GCACTAGTGA ATGTGCAGAT CCCCTTGCTC CTGGGCCAGC TGGTGGAGAT TGTCGCCAAG 
TACACGAGGG ACCACATGGG GAGTTTCGTG TCTGAGTCCC GTAAGCTCAG CGTCCAGCTG 
CTCCTACTGT ACGGTGTTCA GGGACTGCTG ACCTTTGGAT ACCTAGTGCT GCTGTCCCAC 
ATTGGTGAGC GCATGGCCAT GGACATGCGG AAAGCCCTTT TCAGCTCCCT GCTCCGGCAA 
GACATTGCTT TCTTTGATGC CAAAAAGACA GGGCAGCTAG TGAGTCGCTT GACTACTGAT 
GTGCAAGAAT TCAAGTCATC CTTCAAGCTT GTCATCTCCC AGGGACTGCG CAGCTGCACC 
CAGGTGATTG GTAGCCTGGT GTCCCTGTCT ATGCTGTCCC CTCGCCTTAC CCTGATGCTG 
GCTGTCGTCA CACCCGCCCT CATGGGAGTG GGCACCCTGA TGGGCTCAGG CCTCCGAAAG 
CTGTCTCGCC AGTGTCAGGA GCAGATTGCC AGGGCAACAG GTGTAGCAGA TGAGGCCCTT 
GGCAATGTTC GGACTGTGCG GGCCTTCGCG ATGGAGAAGA GGGAGGAGGA ACGCTATCAA 
GCAGAACTGG AGTCATGCTG CTGTAAAGCA GAAGAACTGG GCAGGGGCAT CGCCTTGTTC 
CAAGGGCTCT CCAACATCGC TTTCAACTGT ATGGTCTTGG GCACCCTGTT CATTGGGGGC 
TCCCTTGTGG CTGGACAGCA GCTGAAAGGG GGAGACCTCA TGTCCTTCCT GGTGGCTTCC 
CAGACAGTAC AGAGGTCTAT GGCCAGCCTC TCTGTCCTGT TTGGTCAGGT GGTACGTGGG 
CTGAGTGCGG GAGCCCGAGT CTTCGAATAC ATGGCCCTGA GCCCTGTCAT CCCATTGACC 
GGGGGCTACT GCATCCCCAA CAAGGACATT CGTGGTTCCA TCACCTTCCA AAATGTCACC 
TTCAGCTACC CCTGCAGACC TGGCTTCAAT GTGCTCAAGG ACTTCACCCT GAAGCTGCCC 
TCTGGCAAGA TTGTGGCTCT TGTGGGCCAG TCTGGGGGAG GAAAGACCAC AGTTGCCTCC 
TTGCTGGAAC GCTTCTATGA CCCTGAAGCT GGCTCGGTGA CGTTGGATGG GCATGACCTG 
CGAACTCTCA ACCCCTCCTG GCTCCGGGGC CAGGTCATAG GTTTCATCAG CCAGGAGCCA 
GTCCTGTTTG CAACAACCAT CATGGAGAAT ATCCGATTTG GGAAGCTGGA TGCTTCCGAT 
GAAGAGGTGT ACACAGCTGC ACGAGAAGCC AATGCCCACG AGTTCATCAG CAGCTTCCCC 
GATGGCTACA GCACTGTGGT TGGTGAGCGG GGCACAACCT TGTCTGGTGG CCAGAAGCAG 
CGCCTAGCCA TCGCACGTGC CCTCATCAAG CAGCCCACAG TGCTGATCCT GGACGAGGCC 
ACCAGTGCGC TAGATGCAGA ATCCGAGAGG GTGGTACAGG AGGCCCTGGA CCGGGCCAGT 
GCTGGCCGCA CCGTGTTGGT CATTGCCCAC CGGCTTAGTA CTGTCCGTGC AGCCCACTCC 
ATCATTGTCA TGGCCAATGG CCAAGTCTGT GAGGCTGGGA CCCACGAAGA ACTCCTTAAA 
AAAGGCGGGC TCTATTCAGA GCTTATCCGG AGACAAACCC TGGACGCCTC ACTGACCTCA 
ACCCCTCCTG CAGAGAAGCC TGAAGACCCC AAAAGCTGCC AGTCCAAAGC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006535875.1
CDS	356..2509
Translation	MLVHLFRFGIRGGPVPGWSLQSLRFQTFSAARSSDDRLSSHLLRTVAQLRVQLRAHLPRAPPASHWSPSAWCWVGGTLVVPAVLWQHPRLCLIALCEAKESPPAQPTRAPELRFNWKLFWHFLHPHLLALGAAIVLALGAALVNVQIPLLLGQLVEIVAKYTRDHMGSFVSESRKLSVQLLLLYGVQGLLTFGYLVLLSHIGERMAMDMRKALFSSLLRQDIAFFDAKKTGQLVSRLTTDVQEFKSSFKLVISQGLRSCTQVIGSLVSLSMLSPRLTLMLAVVTPALMGVGTLMGSGLRKLSRQCQEQIARATGVADEALGNVRTVRAFAMEKREEERYQAELESCCCKAEELGRGIALFQGLSNIAFNCMVLGTLFIGGSLVAGQQLKGGDLMSFLVASQTVQRSMASLSVLFGQVVRGLSAGARVFEYMALSPVIPLTGGYCIPNKDIRGSITFQNVTFSYPCRPGFNVLKDFTLKLPSGKIVALVGQSGGGKTTVASLLERFYDPEAGSVTLDGHDLRTLNPSWLRGQVIGFISQEPVLFATTIMENIRFGKLDASDEEVYTAAREANAHEFISSFPDGYSTVVGERGTTLSGGQKQRLAIARALIKQPTVLILDEATSALDAESERVVQEALDRASAGRTVLVIAHRLSTVRAAHSIIVMANGQVCEAGTHEELLKKGGLYSELIRRQTLDASLTSTPPAEKPEDPKSCQSKA

Target ORF information:

RefSeq Version	XM_006535812.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus ATP-binding cassette, sub-family B (MDR/TAP), member 8 (Abcb8), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006535812.1

ORF Insert Sequence:

ATGTTGGTGC ACTTATTTCG GTTCGGAATC CGGGGTGGCC CAGTTCCAGG ATGGTCGCTA 
CAATCCCTGC GCTTCCAGAC GTTCTCTGCC GCCAGGTCCT CAGATGACCG GCTCAGCTCA 
CACCTCCTGC GGACTGTAGC CCAGCTCCGT GTACAGCTCC GGGCTCACCT CCCTCGAGCC 
CCACCAGCTT CCCACTGGAG CCCCTCTGCC TGGTGTTGGG TTGGGGGGAC CTTGGTGGTC 
CCTGCAGTCC TGTGGCAGCA TCCACGCCTC TGCCTTATAG CACTATGTGA GGCCAAAGAG 
TCCCCTCCTG CCCAGCCCAC ACGTGCCCCA GAGCTGCGCT TTAATTGGAA GCTCTTCTGG 
CATTTCCTTC ACCCCCACCT GCTGGCCTTG GGGGCAGCCA TTGTGCTGGC CTTAGGTGCG 
GCACTAGTGA ATGTGCAGAT CCCCTTGCTC CTGGGCCAGC TGGTGGAGAT TGTCGCCAAG 
TACACGAGGG ACCACATGGG GAGTTTCGTG TCTGAGTCCC GTAAGCTCAG CGTCCAGCTG 
CTCCTACTGT ACGGTGTTCA GGGACTGCTG ACCTTTGGAT ACCTAGTGCT GCTGTCCCAC 
ATTGGTGAGC GCATGGCCAT GGACATGCGG AAAGCCCTTT TCAGCTCCCT GCTCCGGCAA 
GACATTGCTT TCTTTGATGC CAAAAAGACA GGGCAGCTAG TGAGTCGCTT GACTACTGAT 
GTGCAAGAAT TCAAGTCATC CTTCAAGCTT GTCATCTCCC AGGGACTGCG CAGCTGCACC 
CAGGTGATTG GTAGCCTGGT GTCCCTGTCT ATGCTGTCCC CTCGCCTTAC CCTGATGCTG 
GCTGTCGTCA CACCCGCCCT CATGGGAGTG GGCACCCTGA TGGGCTCAGG CCTCCGAAAG 
CTGTCTCGCC AGTGTCAGGA GCAGATTGCC AGGGCAACAG GTGTAGCAGA TGAGGCCCTT 
GGCAATGTTC GGACTGTGCG GGCCTTCGCG ATGGAGAAGA GGGAGGAGGA ACGCTATCAA 
GCAGAACTGG AGTCATGCTG CTGTAAAGCA GAAGAACTGG GCAGGGGCAT CGCCTTGTTC 
CAAGGGCTCT CCAACATCGC TTTCAACTGT ATGGTCTTGG GCACCCTGTT CATTGGGGGC 
TCCCTTGTGG CTGGACAGCA GCTGAAAGGG GGAGACCTCA TGTCCTTCCT GGTGGCTTCC 
CAGACAGTAC AGAGGTCTAT GGCCAGCCTC TCTGTCCTGT TTGGTCAGGT GGTACGTGGG 
CTGAGTGCGG GAGCCCGAGT CTTCGAATAC ATGGCCCTGA GCCCTGTCAT CCCATTGACC 
GGGGGCTACT GCATCCCCAA CAAGGACATT CGTGGTTCCA TCACCTTCCA AAATGTCACC 
TTCAGCTACC CCTGCAGACC TGGCTTCAAT GTGCTCAAGG ACTTCACCCT GAAGCTGCCC 
TCTGGCAAGA TTGTGGCTCT TGTGGGCCAG TCTGGGGGAG GAAAGACCAC AGTTGCCTCC 
TTGCTGGAAC GCTTCTATGA CCCTGAAGCT GGCTCGGTGA CGTTGGATGG GCATGACCTG 
CGAACTCTCA ACCCCTCCTG GCTCCGGGGC CAGGTCATAG GTTTCATCAG CCAGGAGCCA 
GTCCTGTTTG CAACAACCAT CATGGAGAAT ATCCGATTTG GGAAGCTGGA TGCTTCCGAT 
GAAGAGGTGT ACACAGCTGC ACGAGAAGCC AATGCCCACG AGTTCATCAG CAGCTTCCCC 
GATGGCTACA GCACTGTGGT TGGTGAGCGG GGCACAACCT TGTCTGGTGG CCAGAAGCAG 
CGCCTAGCCA TCGCACGTGC CCTCATCAAG CAGCCCACAG TGCTGATCCT GGACGAGGCC 
ACCAGTGCGC TAGATGCAGA ATCCGAGAGG GTGGTACAGG AGGCCCTGGA CCGGGCCAGT 
GCTGGCCGCA CCGTGTTGGT CATTGCCCAC CGGCTTAGTA CTGTCCGTGC AGCCCACTCC 
ATCATTGTCA TGGCCAATGG CCAAGTCTGT GAGGCTGGGA CCCACGAAGA ACTCCTTAAA 
AAAGGCGGGC TCTATTCAGA GCTTATCCGG AGACAAACCC TGGACGCCTC ACTGACCTCA 
ACCCCTCCTG CAGAGAAGCC TGAAGACCCC AAAAGCTGCC AGTCCAAAGC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Reduction in mitochondrial iron alleviates cardiac damage during injury.
EMBO molecular medicine8(3)247-67(2016 Mar)
Chang HC,Wu R,Shang M,Sato T,Chen C,Shapiro JS,Liu T,Thakur A,Sawicki KT,Prasad SV,Ardehali H

Cardiotoxicity of doxorubicin is mediated through mitochondrial iron accumulation.
The Journal of clinical investigation124(2)617-30(2014 Feb)
Ichikawa Y,Ghanefar M,Bayeva M,Wu R,Khechaduri A,Naga Prasad SV,Mutharasan RK,Naik TJ,Ardehali H

Disruption of ATP-binding cassette B8 in mice leads to cardiomyopathy through a decrease in mitochondrial iron export.
Proceedings of the National Academy of Sciences of the United States of America109(11)4152-7(2012 Mar)
Ichikawa Y,Bayeva M,Ghanefar M,Potini V,Sun L,Mutharasan RK,Wu R,Khechaduri A,Jairaj Naik T,Ardehali H

Identification of 18 mouse ABC genes and characterization of the ABC superfamily in Mus musculus.
Genomics64(1)24-31(2000 Feb)
Schriml LM,Dean M

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Abcb8 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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