ABCB8 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ABCB8
Entrez Gene ID	11194
Full Name	ATP binding cassette subfamily B member 8
Synonyms	EST328128,M-ABC1,MABC1
General protein information	Preferred Names ATP binding cassette subfamily B member 8 Names ATP-binding cassette sub-family B member 8, mitochondrial ATP-binding cassette, sub-family B (MDR/TAP), member 8 mitochondrial ABC protein mitochondrial ATP-binding cassette 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 7 Map Location: 7q36.1
Summary	This nuclear gene encodes a multi-pass membrane protein that is targeted to the mitochondrial inner membrane. The encoded protein is an ATP-dependent transporter that may mediate the passage of organic and inorganic molecules out of the mitochondria. Loss of function of the related gene in mouse results in a disruption of iron homeostasis between the mitochondria and cytosol. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013].
Disorder MIM:	605464

mRNA and Protein(s)

mRNA	Protein	Name
NM_001282291.1	NP_001269220.1	ATP-binding cassette sub-family B member 8, mitochondrial isoform a
NM_001282292.2	NP_001269221.1	mitochondrial potassium channel ATP-binding subunit isoform c
NM_007188.5	NP_009119.2	mitochondrial potassium channel ATP-binding subunit isoform b
NM_007188.4	NP_009119.2	ATP-binding cassette sub-family B member 8, mitochondrial isoform b
NM_001282292.1	NP_001269221.1	ATP-binding cassette sub-family B member 8, mitochondrial isoform c
NM_001282293.1	NP_001269222.1	mitochondrial potassium channel ATP-binding subunit isoform d
NM_001282291.2	NP_001269220.1	mitochondrial potassium channel ATP-binding subunit isoform a

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	ABCB8	XP_519524.3
Canis lupus familiaris (dog)	ABCB8	XP_539916.2
Mus musculus (house mouse)	Abcb8	NP_083296.2
Bos taurus (cattle)	ABCB8	NP_001068994.2
Gallus gallus (chicken)	ABCB8	XP_004939090.1
Danio rerio (zebrafish)	abcb8	NP_001017544.1
Caenorhabditis elegans (roundworm)	haf-6	NP_490828.3
Drosophila melanogaster (fruit fly)	CG1824	NP_572810.1
Homo sapiens (human)	ABCB8	NP_009119.2
	ABCB8	XP_001101695.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP006273	XP_316337.4
Xenopus tropicalis (tropical clawed frog)	abcb8	NP_001121515.1
Rattus norvegicus (Norway rat)	Abcb8	NP_001007797.1

Gene Ontology
Bibliography

Related articles in PubMed

Profiling of ABC transporters during active ulcerative colitis and in vitro effect of inflammatory modulators.
Verma N, Ahuja V, Paul J
Digestive diseases and sciences58(8)2282-92(2013 Aug)

Disruption of ATP-binding cassette B8 in mice leads to cardiomyopathy through a decrease in mitochondrial iron export.
Ichikawa Y, Bayeva M, Ghanefar M, Potini V, Sun L, Mutharasan RK, Wu R, Khechaduri A, Jairaj Naik T, Ardehali H
Proceedings of the National Academy of Sciences of the United States of America109(11)4152-7(2012 Mar)

Mithramycin A suppresses expression of the human melanoma-associated gene ABCB8.
Sachrajda I, Ratajewski M
Molecular genetics and genomics : MGG285(1)57-65(2011 Jan)

Mitochondrial ABC proteins in health and disease.
Zutz A, Gompf S, Sch?gger H, Tamp? R
Biochimica et biophysica acta1787(6)681-90(2009 Jun)

Exclusion of ABCB8 and ABCB10 as cancer candidate genes in acute myeloid leukemia.
Tang L, Bergevoet SM, Franssen LE, de Witte T, Jansen JH, Raymakers RA, van der Reijden BA
Leukemia23(5)1000-2(2009 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
Title: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.

Observational study of gene-disease association. (HuGE Navigator)
Title: Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.

Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.

Observational study of gene-disease association. (HuGE Navigator)
Title: Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.

Observational study of gene-disease association. (HuGE Navigator)
Title: Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects.

The following ABCB8 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ABCB8 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu07817	NM_007188.5 Latest version!	Homo sapiens ATP binding cassette subfamily B member 8 (ABCB8), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
OHu08204	NM_001282292.2 Latest version!	Homo sapiens ATP binding cassette subfamily B member 8 (ABCB8), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
OHu01299	NM_001282293.1 Latest version!	Homo sapiens ATP binding cassette subfamily B member 8 (ABCB8), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu07658	NM_001282291.2 Latest version!	Homo sapiens ATP binding cassette subfamily B member 8 (ABCB8), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
View Old Accession Versions >>
OHu07817	NM_007188.4	Homo sapiens ATP binding cassette subfamily B member 8 (ABCB8), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
OHu08204	NM_001282292.1	Homo sapiens ATP binding cassette subfamily B member 8 (ABCB8), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
OHu07658	NM_001282291.1	Homo sapiens ATP binding cassette subfamily B member 8 (ABCB8), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ABCB8 ( NM_007188.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_009119.2 Homo sapiens ATP binding cassette subfamily B member 8 (ABCB8), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu07817
Clone ID Related Accession (Same CDS sequence)	NM_007188.5 , NM_007188.4
Accession Version	NM_007188.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2157bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-16
Organism	Homo sapiens(human)
Product	mitochondrial potassium channel ATP-binding subunit isoform b
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK222911.1 and AC010973.7. On Jun 2, 2019 this sequence version replaced NM_007188.4. Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region, compared to variant 1. The encoded isoform (b) is shorter than isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.19273.1, SRR7410570.423181.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCTGGTGC ATTTATTTCG GGTCGGGATT CGGGGTGGCC CATTCCCAGG CAGGCTGCTA 
CCGCCCCTCC GCTTCCAGAC ATTCTCAGCT GTCAGGTACT CTGATGGCTA CCGCAGCTCC 
TCCCTCCTCC GGGCCGTGGC CCACCTGCGG TCCCAGCTCT GGGCCCACCT CCCTCGAGCC 
CCCCTAGCTC CCAGATGGAG CCCCTCTGCC TGGTGCTGGG TTGGGGGAGC CCTGCTAGGC 
CCCATGGTAC TGAGTAAGCA TCCCCACCTC TGCCTTGTGG CCCTGTGTGA GGCAGAAGAG 
GCCCCTCCTG CCAGCTCCAC ACCCCATGTC GTGGGGTCTC GCTTTAACTG GAAGCTCTTC 
TGGCAGTTTC TGCACCCCCA CCTGCTGGTC CTGGGGGTAG CCGTCGTGCT GGCCTTGGGT 
GCGGCACTCG TGAATGTACA GATCCCCCTG CTCCTGGGCC AGCTGGTAGA GGTCGTGGCC 
AAGTACACAA GGGACCACGT AGGGAGTTTC ATGACTGAGT CCCAGAATCT CAGCACCCAC 
CTGCTTATCC TCTATGGTGT CCAGGGACTG CTGACCTTCG GGTACCTGGT GCTGCTGTCC 
CACGTTGGCG AGCGCATGGC TGTGGACATG CGGAGGGCCC TCTTCAGCTC CCTGCTCCGA 
CAAGACATCA CCTTCTTTGA CGCCAATAAG ACAGGGCAGC TGGTGAGCCG CTTGACAACT 
GACGTGCAGG AGTTTAAGTC ATCCTTCAAG CTTGTCATCT CCCAGGGGCT GCGAAGCTGC 
ACCCAGGTGG CAGGCTGCCT GGTGTCCCTG TCCATGCTGT CGACACGCCT CACGCTGCTG 
CTGATGGTGG CCACACCAGC CCTGATGGGA GTGGGCACCC TGATGGGCTC AGGCCTCCGA 
AAATTGTCTC GCCAGTGTCA GGAGCAGATC GCCAGGGCAA TGGGCGTAGC AGACGAGGCC 
CTGGGCAATG TGCGGACTGT GCGTGCCTTC GCCATGGAGC AACGGGAAGA GGAGCGCTAT 
GGGGCAGAGC TGGAAGCCTG CCGCTGCCGG GCAGAGGAGC TGGGCCGCGG CATCGCCTTG 
TTCCAAGGGC TTTCCAACAT CGCCTTCAAC TGCATGGTCT TGGGTACCCT ATTTATTGGG 
GGCTCCCTTG TGGCCGGACA GCAGCTGACA GGGGGAGACC TCATGTCCTT CCTGGTGGCC 
TCCCAGACAG TGCAAAGGTC CATGGCCAAC CTCTCTGTCC TGTTTGGGCA GGTGGTCCGG 
GGGCTGAGTG CAGGTGCCCG GGTCTTTGAG TACATGGCCC TGAACCCCTG CATCCCACTG 
TCTGGGGGCT GCTGCGTCCC CAAAGAGCAG CTGCGTGGCT CCGTTACATT TCAGAACGTC 
TGCTTCAGCT ACCCCTGCCG CCCCGGCTTC GAGGTGCTGA AAGACTTCAC CCTGACGCTG 
CCCCCTGGCA AGATCGTGGC CCTCGTGGGC CAGTCTGGCG GAGGAAAGAC CACCGTGGCT 
TCCCTGCTGG AGCGCTTCTA CGACCCCACG GCAGGCGTGG TGATGCTGGA TGGGCGGGAC 
CTGCGCACCC TTGACCCCTC CTGGCTCCGG GGCCAGGTTG TCGGCTTCAT CAGCCAGGAG 
CCCGTCCTGT TTGGGACGAC CATCATGGAA AACATCCGCT TTGGGAAGCT GGAAGCTTCC 
GATGAAGAGG TGTACACAGC CGCCCGGGAA GCGAATGCTC ACGAGTTCAT CACCAGCTTC 
CCCGAGGGCT ACAACACGGT CGTCGGTGAA CGGGGCACTA CCCTGTCTGG GGGCCAGAAG 
CAGCGCCTGG CCATCGCCCG AGCCCTTATC AAGCAGCCCA CGGTGCTGAT ACTGGATGAA 
GCTACCAGCG CGCTGGATGC AGAGTCCGAG CGGGTTGTAC AGGAGGCCCT GGACCGGGCC 
AGTGCAGGCC GCACGGTGCT GGTAATTGCC CACCGGCTCA GCACTGTCCG TGGGGCCCAC 
TGCATTGTCG TCATGGCCGA TGGCCGTGTC TGGGAGGCTG GGACACATGA AGAGCTCCTG 
AAGAAAGGCG GGCTATACGC CGAGCTCATC CGGAGGCAGG CCCTGGATGC CCCGAGGACA 
GCGGCCCCAC CGCCCAAAAA GCCAGAAGGC CCCAGGAGCC ACCAGCACAA GTCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_009119.2
CDS	67..2223
Translation	MLVHLFRVGIRGGPFPGRLLPPLRFQTFSAVRYSDGYRSSSLLRAVAHLRSQLWAHLPRAPLAPRWSPSAWCWVGGALLGPMVLSKHPHLCLVALCEAEEAPPASSTPHVVGSRFNWKLFWQFLHPHLLVLGVAVVLALGAALVNVQIPLLLGQLVEVVAKYTRDHVGSFMTESQNLSTHLLILYGVQGLLTFGYLVLLSHVGERMAVDMRRALFSSLLRQDITFFDANKTGQLVSRLTTDVQEFKSSFKLVISQGLRSCTQVAGCLVSLSMLSTRLTLLLMVATPALMGVGTLMGSGLRKLSRQCQEQIARAMGVADEALGNVRTVRAFAMEQREEERYGAELEACRCRAEELGRGIALFQGLSNIAFNCMVLGTLFIGGSLVAGQQLTGGDLMSFLVASQTVQRSMANLSVLFGQVVRGLSAGARVFEYMALNPCIPLSGGCCVPKEQLRGSVTFQNVCFSYPCRPGFEVLKDFTLTLPPGKIVALVGQSGGGKTTVASLLERFYDPTAGVVMLDGRDLRTLDPSWLRGQVVGFISQEPVLFGTTIMENIRFGKLEASDEEVYTAAREANAHEFITSFPEGYNTVVGERGTTLSGGQKQRLAIARALIKQPTVLILDEATSALDAESERVVQEALDRASAGRTVLVIAHRLSTVRGAHCIVVMADGRVWEAGTHEELLKKGGLYAELIRRQALDAPRTAAPPPKKPEGPRSHQHKS

Target ORF information:

RefSeq Version	NM_007188.5
Organism	Homo sapiens(human)
Definition	Homo sapiens ATP binding cassette subfamily B member 8 (ABCB8), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007188.5

ORF Insert Sequence:

ATGCTGGTGC ATTTATTTCG GGTCGGGATT CGGGGTGGCC CATTCCCAGG CAGGCTGCTA 
CCGCCCCTCC GCTTCCAGAC ATTCTCAGCT GTCAGGTACT CTGATGGCTA CCGCAGCTCC 
TCCCTCCTCC GGGCCGTGGC CCACCTGCGG TCCCAGCTCT GGGCCCACCT CCCTCGAGCC 
CCCCTAGCTC CCAGATGGAG CCCCTCTGCC TGGTGCTGGG TTGGGGGAGC CCTGCTAGGC 
CCCATGGTAC TGAGTAAGCA TCCCCACCTC TGCCTTGTGG CCCTGTGTGA GGCAGAAGAG 
GCCCCTCCTG CCAGCTCCAC ACCCCATGTC GTGGGGTCTC GCTTTAACTG GAAGCTCTTC 
TGGCAGTTTC TGCACCCCCA CCTGCTGGTC CTGGGGGTAG CCGTCGTGCT GGCCTTGGGT 
GCGGCACTCG TGAATGTACA GATCCCCCTG CTCCTGGGCC AGCTGGTAGA GGTCGTGGCC 
AAGTACACAA GGGACCACGT AGGGAGTTTC ATGACTGAGT CCCAGAATCT CAGCACCCAC 
CTGCTTATCC TCTATGGTGT CCAGGGACTG CTGACCTTCG GGTACCTGGT GCTGCTGTCC 
CACGTTGGCG AGCGCATGGC TGTGGACATG CGGAGGGCCC TCTTCAGCTC CCTGCTCCGA 
CAAGACATCA CCTTCTTTGA CGCCAATAAG ACAGGGCAGC TGGTGAGCCG CTTGACAACT 
GACGTGCAGG AGTTTAAGTC ATCCTTCAAG CTTGTCATCT CCCAGGGGCT GCGAAGCTGC 
ACCCAGGTGG CAGGCTGCCT GGTGTCCCTG TCCATGCTGT CGACACGCCT CACGCTGCTG 
CTGATGGTGG CCACACCAGC CCTGATGGGA GTGGGCACCC TGATGGGCTC AGGCCTCCGA 
AAATTGTCTC GCCAGTGTCA GGAGCAGATC GCCAGGGCAA TGGGCGTAGC AGACGAGGCC 
CTGGGCAATG TGCGGACTGT GCGTGCCTTC GCCATGGAGC AACGGGAAGA GGAGCGCTAT 
GGGGCAGAGC TGGAAGCCTG CCGCTGCCGG GCAGAGGAGC TGGGCCGCGG CATCGCCTTG 
TTCCAAGGGC TTTCCAACAT CGCCTTCAAC TGCATGGTCT TGGGTACCCT ATTTATTGGG 
GGCTCCCTTG TGGCCGGACA GCAGCTGACA GGGGGAGACC TCATGTCCTT CCTGGTGGCC 
TCCCAGACAG TGCAAAGGTC CATGGCCAAC CTCTCTGTCC TGTTTGGGCA GGTGGTCCGG 
GGGCTGAGTG CAGGTGCCCG GGTCTTTGAG TACATGGCCC TGAACCCCTG CATCCCACTG 
TCTGGGGGCT GCTGCGTCCC CAAAGAGCAG CTGCGTGGCT CCGTTACATT TCAGAACGTC 
TGCTTCAGCT ACCCCTGCCG CCCCGGCTTC GAGGTGCTGA AAGACTTCAC CCTGACGCTG 
CCCCCTGGCA AGATCGTGGC CCTCGTGGGC CAGTCTGGCG GAGGAAAGAC CACCGTGGCT 
TCCCTGCTGG AGCGCTTCTA CGACCCCACG GCAGGCGTGG TGATGCTGGA TGGGCGGGAC 
CTGCGCACCC TTGACCCCTC CTGGCTCCGG GGCCAGGTTG TCGGCTTCAT CAGCCAGGAG 
CCCGTCCTGT TTGGGACGAC CATCATGGAA AACATCCGCT TTGGGAAGCT GGAAGCTTCC 
GATGAAGAGG TGTACACAGC CGCCCGGGAA GCGAATGCTC ACGAGTTCAT CACCAGCTTC 
CCCGAGGGCT ACAACACGGT CGTCGGTGAA CGGGGCACTA CCCTGTCTGG GGGCCAGAAG 
CAGCGCCTGG CCATCGCCCG AGCCCTTATC AAGCAGCCCA CGGTGCTGAT ACTGGATGAA 
GCTACCAGCG CGCTGGATGC AGAGTCCGAG CGGGTTGTAC AGGAGGCCCT GGACCGGGCC 
AGTGCAGGCC GCACGGTGCT GGTAATTGCC CACCGGCTCA GCACTGTCCG TGGGGCCCAC 
TGCATTGTCG TCATGGCCGA TGGCCGTGTC TGGGAGGCTG GGACACATGA AGAGCTCCTG 
AAGAAAGGCG GGCTATACGC CGAGCTCATC CGGAGGCAGG CCCTGGATGC CCCGAGGACA 
GCGGCCCCAC CGCCCAAAAA GCCAGAAGGC CCCAGGAGCC ACCAGCACAA GTCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ABCB8 ( NM_007188.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_009119.2 Homo sapiens ATP binding cassette subfamily B member 8 (ABCB8), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu07817
Clone ID Related Accession (Same CDS sequence)	NM_007188.5 , NM_007188.4
Accession Version	NM_007188.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2157bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-23
Organism	Homo sapiens(human)
Product	ATP-binding cassette sub-family B member 8, mitochondrial isoform b
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from HY000407.1, AK222911.1 and AC010973.7. On Aug 28, 2013 this sequence version replaced NM_007188.3. Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region, compared to variant 1. The encoded isoform (b) is shorter than isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.206273.1, BC151235.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCTGGTGC ATTTATTTCG GGTCGGGATT CGGGGTGGCC CATTCCCAGG CAGGCTGCTA 
CCGCCCCTCC GCTTCCAGAC ATTCTCAGCT GTCAGGTACT CTGATGGCTA CCGCAGCTCC 
TCCCTCCTCC GGGCCGTGGC CCACCTGCGG TCCCAGCTCT GGGCCCACCT CCCTCGAGCC 
CCCCTAGCTC CCAGATGGAG CCCCTCTGCC TGGTGCTGGG TTGGGGGAGC CCTGCTAGGC 
CCCATGGTAC TGAGTAAGCA TCCCCACCTC TGCCTTGTGG CCCTGTGTGA GGCAGAAGAG 
GCCCCTCCTG CCAGCTCCAC ACCCCATGTC GTGGGGTCTC GCTTTAACTG GAAGCTCTTC 
TGGCAGTTTC TGCACCCCCA CCTGCTGGTC CTGGGGGTAG CCGTCGTGCT GGCCTTGGGT 
GCGGCACTCG TGAATGTACA GATCCCCCTG CTCCTGGGCC AGCTGGTAGA GGTCGTGGCC 
AAGTACACAA GGGACCACGT AGGGAGTTTC ATGACTGAGT CCCAGAATCT CAGCACCCAC 
CTGCTTATCC TCTATGGTGT CCAGGGACTG CTGACCTTCG GGTACCTGGT GCTGCTGTCC 
CACGTTGGCG AGCGCATGGC TGTGGACATG CGGAGGGCCC TCTTCAGCTC CCTGCTCCGA 
CAAGACATCA CCTTCTTTGA CGCCAATAAG ACAGGGCAGC TGGTGAGCCG CTTGACAACT 
GACGTGCAGG AGTTTAAGTC ATCCTTCAAG CTTGTCATCT CCCAGGGGCT GCGAAGCTGC 
ACCCAGGTGG CAGGCTGCCT GGTGTCCCTG TCCATGCTGT CGACACGCCT CACGCTGCTG 
CTGATGGTGG CCACACCAGC CCTGATGGGA GTGGGCACCC TGATGGGCTC AGGCCTCCGA 
AAATTGTCTC GCCAGTGTCA GGAGCAGATC GCCAGGGCAA TGGGCGTAGC AGACGAGGCC 
CTGGGCAATG TGCGGACTGT GCGTGCCTTC GCCATGGAGC AACGGGAAGA GGAGCGCTAT 
GGGGCAGAGC TGGAAGCCTG CCGCTGCCGG GCAGAGGAGC TGGGCCGCGG CATCGCCTTG 
TTCCAAGGGC TTTCCAACAT CGCCTTCAAC TGCATGGTCT TGGGTACCCT ATTTATTGGG 
GGCTCCCTTG TGGCCGGACA GCAGCTGACA GGGGGAGACC TCATGTCCTT CCTGGTGGCC 
TCCCAGACAG TGCAAAGGTC CATGGCCAAC CTCTCTGTCC TGTTTGGGCA GGTGGTCCGG 
GGGCTGAGTG CAGGTGCCCG GGTCTTTGAG TACATGGCCC TGAACCCCTG CATCCCACTG 
TCTGGGGGCT GCTGCGTCCC CAAAGAGCAG CTGCGTGGCT CCGTTACATT TCAGAACGTC 
TGCTTCAGCT ACCCCTGCCG CCCCGGCTTC GAGGTGCTGA AAGACTTCAC CCTGACGCTG 
CCCCCTGGCA AGATCGTGGC CCTCGTGGGC CAGTCTGGCG GAGGAAAGAC CACCGTGGCT 
TCCCTGCTGG AGCGCTTCTA CGACCCCACG GCAGGCGTGG TGATGCTGGA TGGGCGGGAC 
CTGCGCACCC TTGACCCCTC CTGGCTCCGG GGCCAGGTTG TCGGCTTCAT CAGCCAGGAG 
CCCGTCCTGT TTGGGACGAC CATCATGGAA AACATCCGCT TTGGGAAGCT GGAAGCTTCC 
GATGAAGAGG TGTACACAGC CGCCCGGGAA GCGAATGCTC ACGAGTTCAT CACCAGCTTC 
CCCGAGGGCT ACAACACGGT CGTCGGTGAA CGGGGCACTA CCCTGTCTGG GGGCCAGAAG 
CAGCGCCTGG CCATCGCCCG AGCCCTTATC AAGCAGCCCA CGGTGCTGAT ACTGGATGAA 
GCTACCAGCG CGCTGGATGC AGAGTCCGAG CGGGTTGTAC AGGAGGCCCT GGACCGGGCC 
AGTGCAGGCC GCACGGTGCT GGTAATTGCC CACCGGCTCA GCACTGTCCG TGGGGCCCAC 
TGCATTGTCG TCATGGCCGA TGGCCGTGTC TGGGAGGCTG GGACACATGA AGAGCTCCTG 
AAGAAAGGCG GGCTATACGC CGAGCTCATC CGGAGGCAGG CCCTGGATGC CCCGAGGACA 
GCGGCCCCAC CGCCCAAAAA GCCAGAAGGC CCCAGGAGCC ACCAGCACAA GTCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_009119.2
CDS	95..2251
Translation	MLVHLFRVGIRGGPFPGRLLPPLRFQTFSAVRYSDGYRSSSLLRAVAHLRSQLWAHLPRAPLAPRWSPSAWCWVGGALLGPMVLSKHPHLCLVALCEAEEAPPASSTPHVVGSRFNWKLFWQFLHPHLLVLGVAVVLALGAALVNVQIPLLLGQLVEVVAKYTRDHVGSFMTESQNLSTHLLILYGVQGLLTFGYLVLLSHVGERMAVDMRRALFSSLLRQDITFFDANKTGQLVSRLTTDVQEFKSSFKLVISQGLRSCTQVAGCLVSLSMLSTRLTLLLMVATPALMGVGTLMGSGLRKLSRQCQEQIARAMGVADEALGNVRTVRAFAMEQREEERYGAELEACRCRAEELGRGIALFQGLSNIAFNCMVLGTLFIGGSLVAGQQLTGGDLMSFLVASQTVQRSMANLSVLFGQVVRGLSAGARVFEYMALNPCIPLSGGCCVPKEQLRGSVTFQNVCFSYPCRPGFEVLKDFTLTLPPGKIVALVGQSGGGKTTVASLLERFYDPTAGVVMLDGRDLRTLDPSWLRGQVVGFISQEPVLFGTTIMENIRFGKLEASDEEVYTAAREANAHEFITSFPEGYNTVVGERGTTLSGGQKQRLAIARALIKQPTVLILDEATSALDAESERVVQEALDRASAGRTVLVIAHRLSTVRGAHCIVVMADGRVWEAGTHEELLKKGGLYAELIRRQALDAPRTAAPPPKKPEGPRSHQHKS

Target ORF information:

RefSeq Version	NM_007188.4
Organism	Homo sapiens(human)
Definition	Homo sapiens ATP binding cassette subfamily B member 8 (ABCB8), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007188.4

ORF Insert Sequence:

ATGCTGGTGC ATTTATTTCG GGTCGGGATT CGGGGTGGCC CATTCCCAGG CAGGCTGCTA 
CCGCCCCTCC GCTTCCAGAC ATTCTCAGCT GTCAGGTACT CTGATGGCTA CCGCAGCTCC 
TCCCTCCTCC GGGCCGTGGC CCACCTGCGG TCCCAGCTCT GGGCCCACCT CCCTCGAGCC 
CCCCTAGCTC CCAGATGGAG CCCCTCTGCC TGGTGCTGGG TTGGGGGAGC CCTGCTAGGC 
CCCATGGTAC TGAGTAAGCA TCCCCACCTC TGCCTTGTGG CCCTGTGTGA GGCAGAAGAG 
GCCCCTCCTG CCAGCTCCAC ACCCCATGTC GTGGGGTCTC GCTTTAACTG GAAGCTCTTC 
TGGCAGTTTC TGCACCCCCA CCTGCTGGTC CTGGGGGTAG CCGTCGTGCT GGCCTTGGGT 
GCGGCACTCG TGAATGTACA GATCCCCCTG CTCCTGGGCC AGCTGGTAGA GGTCGTGGCC 
AAGTACACAA GGGACCACGT AGGGAGTTTC ATGACTGAGT CCCAGAATCT CAGCACCCAC 
CTGCTTATCC TCTATGGTGT CCAGGGACTG CTGACCTTCG GGTACCTGGT GCTGCTGTCC 
CACGTTGGCG AGCGCATGGC TGTGGACATG CGGAGGGCCC TCTTCAGCTC CCTGCTCCGA 
CAAGACATCA CCTTCTTTGA CGCCAATAAG ACAGGGCAGC TGGTGAGCCG CTTGACAACT 
GACGTGCAGG AGTTTAAGTC ATCCTTCAAG CTTGTCATCT CCCAGGGGCT GCGAAGCTGC 
ACCCAGGTGG CAGGCTGCCT GGTGTCCCTG TCCATGCTGT CGACACGCCT CACGCTGCTG 
CTGATGGTGG CCACACCAGC CCTGATGGGA GTGGGCACCC TGATGGGCTC AGGCCTCCGA 
AAATTGTCTC GCCAGTGTCA GGAGCAGATC GCCAGGGCAA TGGGCGTAGC AGACGAGGCC 
CTGGGCAATG TGCGGACTGT GCGTGCCTTC GCCATGGAGC AACGGGAAGA GGAGCGCTAT 
GGGGCAGAGC TGGAAGCCTG CCGCTGCCGG GCAGAGGAGC TGGGCCGCGG CATCGCCTTG 
TTCCAAGGGC TTTCCAACAT CGCCTTCAAC TGCATGGTCT TGGGTACCCT ATTTATTGGG 
GGCTCCCTTG TGGCCGGACA GCAGCTGACA GGGGGAGACC TCATGTCCTT CCTGGTGGCC 
TCCCAGACAG TGCAAAGGTC CATGGCCAAC CTCTCTGTCC TGTTTGGGCA GGTGGTCCGG 
GGGCTGAGTG CAGGTGCCCG GGTCTTTGAG TACATGGCCC TGAACCCCTG CATCCCACTG 
TCTGGGGGCT GCTGCGTCCC CAAAGAGCAG CTGCGTGGCT CCGTTACATT TCAGAACGTC 
TGCTTCAGCT ACCCCTGCCG CCCCGGCTTC GAGGTGCTGA AAGACTTCAC CCTGACGCTG 
CCCCCTGGCA AGATCGTGGC CCTCGTGGGC CAGTCTGGCG GAGGAAAGAC CACCGTGGCT 
TCCCTGCTGG AGCGCTTCTA CGACCCCACG GCAGGCGTGG TGATGCTGGA TGGGCGGGAC 
CTGCGCACCC TTGACCCCTC CTGGCTCCGG GGCCAGGTTG TCGGCTTCAT CAGCCAGGAG 
CCCGTCCTGT TTGGGACGAC CATCATGGAA AACATCCGCT TTGGGAAGCT GGAAGCTTCC 
GATGAAGAGG TGTACACAGC CGCCCGGGAA GCGAATGCTC ACGAGTTCAT CACCAGCTTC 
CCCGAGGGCT ACAACACGGT CGTCGGTGAA CGGGGCACTA CCCTGTCTGG GGGCCAGAAG 
CAGCGCCTGG CCATCGCCCG AGCCCTTATC AAGCAGCCCA CGGTGCTGAT ACTGGATGAA 
GCTACCAGCG CGCTGGATGC AGAGTCCGAG CGGGTTGTAC AGGAGGCCCT GGACCGGGCC 
AGTGCAGGCC GCACGGTGCT GGTAATTGCC CACCGGCTCA GCACTGTCCG TGGGGCCCAC 
TGCATTGTCG TCATGGCCGA TGGCCGTGTC TGGGAGGCTG GGACACATGA AGAGCTCCTG 
AAGAAAGGCG GGCTATACGC CGAGCTCATC CGGAGGCAGG CCCTGGATGC CCCGAGGACA 
GCGGCCCCAC CGCCCAAAAA GCCAGAAGGC CCCAGGAGCC ACCAGCACAA GTCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ABCB8 ( NM_001282292.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001269221.1 Homo sapiens ATP binding cassette subfamily B member 8 (ABCB8), transcript variant 3, mRNA.

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CloneID	OHu08204
Clone ID Related Accession (Same CDS sequence)	NM_001282292.2 , NM_001282292.1
Accession Version	NM_001282292.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2082bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-16
Organism	Homo sapiens(human)
Product	mitochondrial potassium channel ATP-binding subunit isoform c
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from HY000407.1, BC141836.1 and AC010973.7. On Jun 2, 2019 this sequence version replaced NM_001282292.1. Transcript Variant: This variant (3) lacks an alternate in-frame exon in the 5' coding region and uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. The encoded isoform (c) is shorter than isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803616.30673.1, BC141836.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142348, SAMEA2142670 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCTGGTGC ATTTATTTCG GGTCGGGATT CGGGGTGGCC CATTCCCAGG CAGGCTGCTA 
CCGCCCCTCC GCTTCCAGAC ATTCTCAGCT GTCAGGTACT CTGATGGCTA CCGCAGCTCC 
TCCCTCCTCC GGGCCGTGGC CCACCTGCGG TCCCAGCTCT GGGCCCACCT CCCTCGAGCC 
CCCCTAGCTC CCAGATGGAG CCCCTCTGCC TGGTGCTGGG TTGGGGGAGC CCTGCTAGGC 
CCCATGGTAC TGAGTAAGCA TCCCCACCTC TGCCTTGTGG CCCTGTGTGA GGCAGAAGAG 
GCCCCTCCTG CCAGCTCCAC ACCCCATGTC GTGGGGTCTC GCTTTAACTG GAAGCTCTTC 
TGGCAGTTTC TGCACCCCCA CCTGCTGGTC CTGGGGGTAG CCGTCGTGCT GGCCTTGGGT 
GCGGCACTCG TGAATGTACA GATCCCCCTG CTCCTGGGCC AGCTGGTAGA GGTCGTGGCC 
AAGTACACAA GGGACCACGT AGGGAGTTTC ATGACTGAGT CCCAGAATCT CAGCACCCAC 
CTGCTTATCC TCTATGGTGT CCAGGGACTG CTGACCTTCG GGTACCTGGT GCTGCTGTCC 
CACGTTGGCG AGCGCATGGC TGTGGACATG CGGAGGGCCC TCTTCAGCTC CCTGCTCCGA 
CAAGACATCA CCTTCTTTGA CGCCAATAAG ACAGGGCAGC TGGTGAGCCG CTTGACAACT 
GACGTGCAGG AGTTTAAGTC ATCCTTCAAG CTTGTCATCT CCCAGGGGCT GCGAAGCTGC 
ACCCAGGTGG CAGGCTGCCT GGTGTCCCTG TCCATGCTGT CGACACGCCT CACGCTGCTG 
CTGATGGTGG CCACACCAGC CCTGATGGGA GTGGGCACCC TGATGGGCTC AGGCCTCCGA 
AAATTGTCTC GCCAGTGTCA GGAGCAGATC GCCAGGGCAA TGGGCGTAGC AGACGAGGCC 
CTGGGCAATG TGCGGACTGT GCGTGCCTTC GCCATGGAGC AACGGGAAGA GGAGCGCTAT 
GGGGCAGAGC TGGAAGCCTG CCGCTGCCGG GCAGAGGAGC TGGGCCGCGG CATCGCCTTG 
TTCCAAGGGC TTTCCAACAT CGCCTTCAAC TGCATGGTCT TGGGTACCCT ATTTATTGGG 
GGCTCCCTTG TGGCCGGACA GCAGCTGACA GGGGGAGACC TCATGTCCTT CCTGGTGGCC 
TCCCAGACAG TGCAAAGGTC CATGGCCAAC CTCTCTGTCC TGTTTGGGCA GGTGGTCCGG 
GGGCTGAGTG CAGGTGCCCG GGTCTTTGAG TACATGGCCC TGAACCCCTG CATCCCACTG 
TCTGGGGGCT GCTGCGTCCC CAAAGAGCAG CTGCGTGGCT CCGTTACATT TCAGAACGTC 
TGCTTCAGCT ACCCCTGCCG CCCCGGCTTC GAGGTGCTGA AAGACTTCAC CCTGACGCTG 
CCCCCTGGCA AGATCGTGGC CCTCGTGGGC CAGTCTGGCG GAGGAAAGAC CACCGTGGCT 
TCCCTGCTGG AGCGCTTCTA CGACCCCACG GCAGGCGTGG TGATGCTGGA TGGGCGGGAC 
CTGCGCACCC TTGACCCCTC CTGGCTCCGG GGCCAGGTTG TCGGCTTCAT CAGCCAGGAG 
CCCGTCCTGT TTGGGACGAC CATCATGGAA AACATCCGCT TTGGGAAGCT GGAAGCTTCC 
GATGAAGAGG TGTACACAGC CGCCCGGGAA GCGAATGCTC ACGAGTTCAT CACCAGCTTC 
CCCGAGGGCT ACAACACGGT CGTCGGTGAA CGGGGCACTA CCCTGTCTGG GGGCCAGAAG 
CAGCGCCTGG CCATCGCCCG AGCCCTTATC AAGCAGCCCA CGGTGCTGAT ACTGGATGAA 
GCTACCAGCG CGCTGGATGC AGAGTCCGAG CGGGTTGTAC AGGAGGCCCT GGACCGGGCC 
AGTGCAGGCC GCACGGTGCT GGCTGGGACA CATGAAGAGC TCCTGAAGAA AGGCGGGCTA 
TACGCCGAGC TCATCCGGAG GCAGGCCCTG GATGCCCCGA GGACAGCGGC CCCACCGCCC 
AAAAAGCCAG AAGGCCCCAG GAGCCACCAG CACAAGTCCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001269221.1
CDS	67..2148
Translation	MLVHLFRVGIRGGPFPGRLLPPLRFQTFSAVRYSDGYRSSSLLRAVAHLRSQLWAHLPRAPLAPRWSPSAWCWVGGALLGPMVLSKHPHLCLVALCEAEEAPPASSTPHVVGSRFNWKLFWQFLHPHLLVLGVAVVLALGAALVNVQIPLLLGQLVEVVAKYTRDHVGSFMTESQNLSTHLLILYGVQGLLTFGYLVLLSHVGERMAVDMRRALFSSLLRQDITFFDANKTGQLVSRLTTDVQEFKSSFKLVISQGLRSCTQVAGCLVSLSMLSTRLTLLLMVATPALMGVGTLMGSGLRKLSRQCQEQIARAMGVADEALGNVRTVRAFAMEQREEERYGAELEACRCRAEELGRGIALFQGLSNIAFNCMVLGTLFIGGSLVAGQQLTGGDLMSFLVASQTVQRSMANLSVLFGQVVRGLSAGARVFEYMALNPCIPLSGGCCVPKEQLRGSVTFQNVCFSYPCRPGFEVLKDFTLTLPPGKIVALVGQSGGGKTTVASLLERFYDPTAGVVMLDGRDLRTLDPSWLRGQVVGFISQEPVLFGTTIMENIRFGKLEASDEEVYTAAREANAHEFITSFPEGYNTVVGERGTTLSGGQKQRLAIARALIKQPTVLILDEATSALDAESERVVQEALDRASAGRTVLAGTHEELLKKGGLYAELIRRQALDAPRTAAPPPKKPEGPRSHQHKS

Target ORF information:

RefSeq Version	NM_001282292.2
Organism	Homo sapiens(human)
Definition	Homo sapiens ATP binding cassette subfamily B member 8 (ABCB8), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001282292.2

ORF Insert Sequence:

ATGCTGGTGC ATTTATTTCG GGTCGGGATT CGGGGTGGCC CATTCCCAGG CAGGCTGCTA 
CCGCCCCTCC GCTTCCAGAC ATTCTCAGCT GTCAGGTACT CTGATGGCTA CCGCAGCTCC 
TCCCTCCTCC GGGCCGTGGC CCACCTGCGG TCCCAGCTCT GGGCCCACCT CCCTCGAGCC 
CCCCTAGCTC CCAGATGGAG CCCCTCTGCC TGGTGCTGGG TTGGGGGAGC CCTGCTAGGC 
CCCATGGTAC TGAGTAAGCA TCCCCACCTC TGCCTTGTGG CCCTGTGTGA GGCAGAAGAG 
GCCCCTCCTG CCAGCTCCAC ACCCCATGTC GTGGGGTCTC GCTTTAACTG GAAGCTCTTC 
TGGCAGTTTC TGCACCCCCA CCTGCTGGTC CTGGGGGTAG CCGTCGTGCT GGCCTTGGGT 
GCGGCACTCG TGAATGTACA GATCCCCCTG CTCCTGGGCC AGCTGGTAGA GGTCGTGGCC 
AAGTACACAA GGGACCACGT AGGGAGTTTC ATGACTGAGT CCCAGAATCT CAGCACCCAC 
CTGCTTATCC TCTATGGTGT CCAGGGACTG CTGACCTTCG GGTACCTGGT GCTGCTGTCC 
CACGTTGGCG AGCGCATGGC TGTGGACATG CGGAGGGCCC TCTTCAGCTC CCTGCTCCGA 
CAAGACATCA CCTTCTTTGA CGCCAATAAG ACAGGGCAGC TGGTGAGCCG CTTGACAACT 
GACGTGCAGG AGTTTAAGTC ATCCTTCAAG CTTGTCATCT CCCAGGGGCT GCGAAGCTGC 
ACCCAGGTGG CAGGCTGCCT GGTGTCCCTG TCCATGCTGT CGACACGCCT CACGCTGCTG 
CTGATGGTGG CCACACCAGC CCTGATGGGA GTGGGCACCC TGATGGGCTC AGGCCTCCGA 
AAATTGTCTC GCCAGTGTCA GGAGCAGATC GCCAGGGCAA TGGGCGTAGC AGACGAGGCC 
CTGGGCAATG TGCGGACTGT GCGTGCCTTC GCCATGGAGC AACGGGAAGA GGAGCGCTAT 
GGGGCAGAGC TGGAAGCCTG CCGCTGCCGG GCAGAGGAGC TGGGCCGCGG CATCGCCTTG 
TTCCAAGGGC TTTCCAACAT CGCCTTCAAC TGCATGGTCT TGGGTACCCT ATTTATTGGG 
GGCTCCCTTG TGGCCGGACA GCAGCTGACA GGGGGAGACC TCATGTCCTT CCTGGTGGCC 
TCCCAGACAG TGCAAAGGTC CATGGCCAAC CTCTCTGTCC TGTTTGGGCA GGTGGTCCGG 
GGGCTGAGTG CAGGTGCCCG GGTCTTTGAG TACATGGCCC TGAACCCCTG CATCCCACTG 
TCTGGGGGCT GCTGCGTCCC CAAAGAGCAG CTGCGTGGCT CCGTTACATT TCAGAACGTC 
TGCTTCAGCT ACCCCTGCCG CCCCGGCTTC GAGGTGCTGA AAGACTTCAC CCTGACGCTG 
CCCCCTGGCA AGATCGTGGC CCTCGTGGGC CAGTCTGGCG GAGGAAAGAC CACCGTGGCT 
TCCCTGCTGG AGCGCTTCTA CGACCCCACG GCAGGCGTGG TGATGCTGGA TGGGCGGGAC 
CTGCGCACCC TTGACCCCTC CTGGCTCCGG GGCCAGGTTG TCGGCTTCAT CAGCCAGGAG 
CCCGTCCTGT TTGGGACGAC CATCATGGAA AACATCCGCT TTGGGAAGCT GGAAGCTTCC 
GATGAAGAGG TGTACACAGC CGCCCGGGAA GCGAATGCTC ACGAGTTCAT CACCAGCTTC 
CCCGAGGGCT ACAACACGGT CGTCGGTGAA CGGGGCACTA CCCTGTCTGG GGGCCAGAAG 
CAGCGCCTGG CCATCGCCCG AGCCCTTATC AAGCAGCCCA CGGTGCTGAT ACTGGATGAA 
GCTACCAGCG CGCTGGATGC AGAGTCCGAG CGGGTTGTAC AGGAGGCCCT GGACCGGGCC 
AGTGCAGGCC GCACGGTGCT GGCTGGGACA CATGAAGAGC TCCTGAAGAA AGGCGGGCTA 
TACGCCGAGC TCATCCGGAG GCAGGCCCTG GATGCCCCGA GGACAGCGGC CCCACCGCCC 
AAAAAGCCAG AAGGCCCCAG GAGCCACCAG CACAAGTCCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ABCB8 ( NM_001282292.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001269221.1 Homo sapiens ATP binding cassette subfamily B member 8 (ABCB8), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu08204
Clone ID Related Accession (Same CDS sequence)	NM_001282292.2 , NM_001282292.1
Accession Version	NM_001282292.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2082bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-23
Organism	Homo sapiens(human)
Product	ATP-binding cassette sub-family B member 8, mitochondrial isoform c
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from HY000407.1, BC141836.1 and AC010973.7. On Aug 28, 2013 this sequence version replaced XM_005249936.1. Transcript Variant: This variant (3) lacks an alternate in-frame exon in the 5' coding region and uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. The encoded isoform (c) is shorter than isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC141836.1, SRR1803616.30673.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142348, SAMEA2142670 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCTGGTGC ATTTATTTCG GGTCGGGATT CGGGGTGGCC CATTCCCAGG CAGGCTGCTA 
CCGCCCCTCC GCTTCCAGAC ATTCTCAGCT GTCAGGTACT CTGATGGCTA CCGCAGCTCC 
TCCCTCCTCC GGGCCGTGGC CCACCTGCGG TCCCAGCTCT GGGCCCACCT CCCTCGAGCC 
CCCCTAGCTC CCAGATGGAG CCCCTCTGCC TGGTGCTGGG TTGGGGGAGC CCTGCTAGGC 
CCCATGGTAC TGAGTAAGCA TCCCCACCTC TGCCTTGTGG CCCTGTGTGA GGCAGAAGAG 
GCCCCTCCTG CCAGCTCCAC ACCCCATGTC GTGGGGTCTC GCTTTAACTG GAAGCTCTTC 
TGGCAGTTTC TGCACCCCCA CCTGCTGGTC CTGGGGGTAG CCGTCGTGCT GGCCTTGGGT 
GCGGCACTCG TGAATGTACA GATCCCCCTG CTCCTGGGCC AGCTGGTAGA GGTCGTGGCC 
AAGTACACAA GGGACCACGT AGGGAGTTTC ATGACTGAGT CCCAGAATCT CAGCACCCAC 
CTGCTTATCC TCTATGGTGT CCAGGGACTG CTGACCTTCG GGTACCTGGT GCTGCTGTCC 
CACGTTGGCG AGCGCATGGC TGTGGACATG CGGAGGGCCC TCTTCAGCTC CCTGCTCCGA 
CAAGACATCA CCTTCTTTGA CGCCAATAAG ACAGGGCAGC TGGTGAGCCG CTTGACAACT 
GACGTGCAGG AGTTTAAGTC ATCCTTCAAG CTTGTCATCT CCCAGGGGCT GCGAAGCTGC 
ACCCAGGTGG CAGGCTGCCT GGTGTCCCTG TCCATGCTGT CGACACGCCT CACGCTGCTG 
CTGATGGTGG CCACACCAGC CCTGATGGGA GTGGGCACCC TGATGGGCTC AGGCCTCCGA 
AAATTGTCTC GCCAGTGTCA GGAGCAGATC GCCAGGGCAA TGGGCGTAGC AGACGAGGCC 
CTGGGCAATG TGCGGACTGT GCGTGCCTTC GCCATGGAGC AACGGGAAGA GGAGCGCTAT 
GGGGCAGAGC TGGAAGCCTG CCGCTGCCGG GCAGAGGAGC TGGGCCGCGG CATCGCCTTG 
TTCCAAGGGC TTTCCAACAT CGCCTTCAAC TGCATGGTCT TGGGTACCCT ATTTATTGGG 
GGCTCCCTTG TGGCCGGACA GCAGCTGACA GGGGGAGACC TCATGTCCTT CCTGGTGGCC 
TCCCAGACAG TGCAAAGGTC CATGGCCAAC CTCTCTGTCC TGTTTGGGCA GGTGGTCCGG 
GGGCTGAGTG CAGGTGCCCG GGTCTTTGAG TACATGGCCC TGAACCCCTG CATCCCACTG 
TCTGGGGGCT GCTGCGTCCC CAAAGAGCAG CTGCGTGGCT CCGTTACATT TCAGAACGTC 
TGCTTCAGCT ACCCCTGCCG CCCCGGCTTC GAGGTGCTGA AAGACTTCAC CCTGACGCTG 
CCCCCTGGCA AGATCGTGGC CCTCGTGGGC CAGTCTGGCG GAGGAAAGAC CACCGTGGCT 
TCCCTGCTGG AGCGCTTCTA CGACCCCACG GCAGGCGTGG TGATGCTGGA TGGGCGGGAC 
CTGCGCACCC TTGACCCCTC CTGGCTCCGG GGCCAGGTTG TCGGCTTCAT CAGCCAGGAG 
CCCGTCCTGT TTGGGACGAC CATCATGGAA AACATCCGCT TTGGGAAGCT GGAAGCTTCC 
GATGAAGAGG TGTACACAGC CGCCCGGGAA GCGAATGCTC ACGAGTTCAT CACCAGCTTC 
CCCGAGGGCT ACAACACGGT CGTCGGTGAA CGGGGCACTA CCCTGTCTGG GGGCCAGAAG 
CAGCGCCTGG CCATCGCCCG AGCCCTTATC AAGCAGCCCA CGGTGCTGAT ACTGGATGAA 
GCTACCAGCG CGCTGGATGC AGAGTCCGAG CGGGTTGTAC AGGAGGCCCT GGACCGGGCC 
AGTGCAGGCC GCACGGTGCT GGCTGGGACA CATGAAGAGC TCCTGAAGAA AGGCGGGCTA 
TACGCCGAGC TCATCCGGAG GCAGGCCCTG GATGCCCCGA GGACAGCGGC CCCACCGCCC 
AAAAAGCCAG AAGGCCCCAG GAGCCACCAG CACAAGTCCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001269221.1
CDS	95..2176
Translation	MLVHLFRVGIRGGPFPGRLLPPLRFQTFSAVRYSDGYRSSSLLRAVAHLRSQLWAHLPRAPLAPRWSPSAWCWVGGALLGPMVLSKHPHLCLVALCEAEEAPPASSTPHVVGSRFNWKLFWQFLHPHLLVLGVAVVLALGAALVNVQIPLLLGQLVEVVAKYTRDHVGSFMTESQNLSTHLLILYGVQGLLTFGYLVLLSHVGERMAVDMRRALFSSLLRQDITFFDANKTGQLVSRLTTDVQEFKSSFKLVISQGLRSCTQVAGCLVSLSMLSTRLTLLLMVATPALMGVGTLMGSGLRKLSRQCQEQIARAMGVADEALGNVRTVRAFAMEQREEERYGAELEACRCRAEELGRGIALFQGLSNIAFNCMVLGTLFIGGSLVAGQQLTGGDLMSFLVASQTVQRSMANLSVLFGQVVRGLSAGARVFEYMALNPCIPLSGGCCVPKEQLRGSVTFQNVCFSYPCRPGFEVLKDFTLTLPPGKIVALVGQSGGGKTTVASLLERFYDPTAGVVMLDGRDLRTLDPSWLRGQVVGFISQEPVLFGTTIMENIRFGKLEASDEEVYTAAREANAHEFITSFPEGYNTVVGERGTTLSGGQKQRLAIARALIKQPTVLILDEATSALDAESERVVQEALDRASAGRTVLAGTHEELLKKGGLYAELIRRQALDAPRTAAPPPKKPEGPRSHQHKS

Target ORF information:

RefSeq Version	NM_001282292.1
Organism	Homo sapiens(human)
Definition	Homo sapiens ATP binding cassette subfamily B member 8 (ABCB8), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001282292.1

ORF Insert Sequence:

ATGCTGGTGC ATTTATTTCG GGTCGGGATT CGGGGTGGCC CATTCCCAGG CAGGCTGCTA 
CCGCCCCTCC GCTTCCAGAC ATTCTCAGCT GTCAGGTACT CTGATGGCTA CCGCAGCTCC 
TCCCTCCTCC GGGCCGTGGC CCACCTGCGG TCCCAGCTCT GGGCCCACCT CCCTCGAGCC 
CCCCTAGCTC CCAGATGGAG CCCCTCTGCC TGGTGCTGGG TTGGGGGAGC CCTGCTAGGC 
CCCATGGTAC TGAGTAAGCA TCCCCACCTC TGCCTTGTGG CCCTGTGTGA GGCAGAAGAG 
GCCCCTCCTG CCAGCTCCAC ACCCCATGTC GTGGGGTCTC GCTTTAACTG GAAGCTCTTC 
TGGCAGTTTC TGCACCCCCA CCTGCTGGTC CTGGGGGTAG CCGTCGTGCT GGCCTTGGGT 
GCGGCACTCG TGAATGTACA GATCCCCCTG CTCCTGGGCC AGCTGGTAGA GGTCGTGGCC 
AAGTACACAA GGGACCACGT AGGGAGTTTC ATGACTGAGT CCCAGAATCT CAGCACCCAC 
CTGCTTATCC TCTATGGTGT CCAGGGACTG CTGACCTTCG GGTACCTGGT GCTGCTGTCC 
CACGTTGGCG AGCGCATGGC TGTGGACATG CGGAGGGCCC TCTTCAGCTC CCTGCTCCGA 
CAAGACATCA CCTTCTTTGA CGCCAATAAG ACAGGGCAGC TGGTGAGCCG CTTGACAACT 
GACGTGCAGG AGTTTAAGTC ATCCTTCAAG CTTGTCATCT CCCAGGGGCT GCGAAGCTGC 
ACCCAGGTGG CAGGCTGCCT GGTGTCCCTG TCCATGCTGT CGACACGCCT CACGCTGCTG 
CTGATGGTGG CCACACCAGC CCTGATGGGA GTGGGCACCC TGATGGGCTC AGGCCTCCGA 
AAATTGTCTC GCCAGTGTCA GGAGCAGATC GCCAGGGCAA TGGGCGTAGC AGACGAGGCC 
CTGGGCAATG TGCGGACTGT GCGTGCCTTC GCCATGGAGC AACGGGAAGA GGAGCGCTAT 
GGGGCAGAGC TGGAAGCCTG CCGCTGCCGG GCAGAGGAGC TGGGCCGCGG CATCGCCTTG 
TTCCAAGGGC TTTCCAACAT CGCCTTCAAC TGCATGGTCT TGGGTACCCT ATTTATTGGG 
GGCTCCCTTG TGGCCGGACA GCAGCTGACA GGGGGAGACC TCATGTCCTT CCTGGTGGCC 
TCCCAGACAG TGCAAAGGTC CATGGCCAAC CTCTCTGTCC TGTTTGGGCA GGTGGTCCGG 
GGGCTGAGTG CAGGTGCCCG GGTCTTTGAG TACATGGCCC TGAACCCCTG CATCCCACTG 
TCTGGGGGCT GCTGCGTCCC CAAAGAGCAG CTGCGTGGCT CCGTTACATT TCAGAACGTC 
TGCTTCAGCT ACCCCTGCCG CCCCGGCTTC GAGGTGCTGA AAGACTTCAC CCTGACGCTG 
CCCCCTGGCA AGATCGTGGC CCTCGTGGGC CAGTCTGGCG GAGGAAAGAC CACCGTGGCT 
TCCCTGCTGG AGCGCTTCTA CGACCCCACG GCAGGCGTGG TGATGCTGGA TGGGCGGGAC 
CTGCGCACCC TTGACCCCTC CTGGCTCCGG GGCCAGGTTG TCGGCTTCAT CAGCCAGGAG 
CCCGTCCTGT TTGGGACGAC CATCATGGAA AACATCCGCT TTGGGAAGCT GGAAGCTTCC 
GATGAAGAGG TGTACACAGC CGCCCGGGAA GCGAATGCTC ACGAGTTCAT CACCAGCTTC 
CCCGAGGGCT ACAACACGGT CGTCGGTGAA CGGGGCACTA CCCTGTCTGG GGGCCAGAAG 
CAGCGCCTGG CCATCGCCCG AGCCCTTATC AAGCAGCCCA CGGTGCTGAT ACTGGATGAA 
GCTACCAGCG CGCTGGATGC AGAGTCCGAG CGGGTTGTAC AGGAGGCCCT GGACCGGGCC 
AGTGCAGGCC GCACGGTGCT GGCTGGGACA CATGAAGAGC TCCTGAAGAA AGGCGGGCTA 
TACGCCGAGC TCATCCGGAG GCAGGCCCTG GATGCCCCGA GGACAGCGGC CCCACCGCCC 
AAAAAGCCAG AAGGCCCCAG GAGCCACCAG CACAAGTCCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ABCB8 ( NM_001282293.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001269222.1 Homo sapiens ATP binding cassette subfamily B member 8 (ABCB8), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu01299
Clone ID Related Accession (Same CDS sequence)	NM_001282293.1
Accession Version	NM_001282293.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1893bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-16
Organism	Homo sapiens(human)
Product	mitochondrial potassium channel ATP-binding subunit isoform d
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from HY000407.1, AK294344.1, AK222911.1 and AC010973.7. On Aug 28, 2013 this sequence version replaced XM_005249939.1. Transcript Variant: This variant (4) lacks two alternate exons in the 5' coding region and initiates translation at an alternate upstream start codon, compared to variant 1. The encoded isoform (d) is shorter and has a distinct N-terminus, compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.217631.1, SRR1660807.85922.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGAGGGTGA AACTGCTATT GCCGGCGGCT CCTGTTTTAC CGCGTCAGCA TGCTGGTGCA 
TTTATTTCGG GTCGGGATTC GGGGTGGCCC ATTCCCAGGC AGGCTGCTAC CGCCCCTCCG 
CTTCCAGACA TTCTCAGCTG TCAGCTGGCC TTGGGTGCGG CACTCGTGAA TGTACAGATC 
CCCCTGCTCC TGGGCCAGCT GGTAGAGGTC GTGGCCAAGT ACACAAGGGA CCACGTAGGG 
AGTTTCATGA CTGAGTCCCA GAATCTCAGC ACCCACCTGC TTATCCTCTA TGGTGTCCAG 
GGACTGCTGA CCTTCGGGTA CCTGGTGCTG CTGTCCCACG TTGGCGAGCG CATGGCTGTG 
GACATGCGGA GGGCCCTCTT CAGCTCCCTG CTCCGACAAG ACATCACCTT CTTTGACGCC 
AATAAGACAG GGCAGCTGGT GAGCCGCTTG ACAACTGACG TGCAGGAGTT TAAGTCATCC 
TTCAAGCTTG TCATCTCCCA GGGGCTGCGA AGCTGCACCC AGGTGGCAGG CTGCCTGGTG 
TCCCTGTCCA TGCTGTCGAC ACGCCTCACG CTGCTGCTGA TGGTGGCCAC ACCAGCCCTG 
ATGGGAGTGG GCACCCTGAT GGGCTCAGGC CTCCGAAAAT TGTCTCGCCA GTGTCAGGAG 
CAGATCGCCA GGGCAATGGG CGTAGCAGAC GAGGCCCTGG GCAATGTGCG GACTGTGCGT 
GCCTTCGCCA TGGAGCAACG GGAAGAGGAG CGCTATGGGG CAGAGCTGGA AGCCTGCCGC 
TGCCGGGCAG AGGAGCTGGG CCGCGGCATC GCCTTGTTCC AAGGGCTTTC CAACATCGCC 
TTCAACTGCA TGGTCTTGGG TACCCTATTT ATTGGGGGCT CCCTTGTGGC CGGACAGCAG 
CTGACAGGGG GAGACCTCAT GTCCTTCCTG GTGGCCTCCC AGACAGTGCA AAGGTCCATG 
GCCAACCTCT CTGTCCTGTT TGGGCAGGTG GTCCGGGGGC TGAGTGCAGG TGCCCGGGTC 
TTTGAGTACA TGGCCCTGAA CCCCTGCATC CCACTGTCTG GGGGCTGCTG CGTCCCCAAA 
GAGCAGCTGC GTGGCTCCGT TACATTTCAG AACGTCTGCT TCAGCTACCC CTGCCGCCCC 
GGCTTCGAGG TGCTGAAAGA CTTCACCCTG ACGCTGCCCC CTGGCAAGAT CGTGGCCCTC 
GTGGGCCAGT CTGGCGGAGG AAAGACCACC GTGGCTTCCC TGCTGGAGCG CTTCTACGAC 
CCCACGGCAG GCGTGGTGAT GCTGGATGGG CGGGACCTGC GCACCCTTGA CCCCTCCTGG 
CTCCGGGGCC AGGTTGTCGG CTTCATCAGC CAGGAGCCCG TCCTGTTTGG GACGACCATC 
ATGGAAAACA TCCGCTTTGG GAAGCTGGAA GCTTCCGATG AAGAGGTGTA CACAGCCGCC 
CGGGAAGCGA ATGCTCACGA GTTCATCACC AGCTTCCCCG AGGGCTACAA CACGGTCGTC 
GGTGAACGGG GCACTACCCT GTCTGGGGGC CAGAAGCAGC GCCTGGCCAT CGCCCGAGCC 
CTTATCAAGC AGCCCACGGT GCTGATACTG GATGAAGCTA CCAGCGCGCT GGATGCAGAG 
TCCGAGCGGG TTGTACAGGA GGCCCTGGAC CGGGCCAGTG CAGGCCGCAC GGTGCTGGTA 
ATTGCCCACC GGCTCAGCAC TGTCCGTGGG GCCCACTGCA TTGTCGTCAT GGCCGATGGC 
CGTGTCTGGG AGGCTGGGAC ACATGAAGAG CTCCTGAAGA AAGGCGGGCT ATACGCCGAG 
CTCATCCGGA GGCAGGCCCT GGATGCCCCG AGGACAGCGG CCCCACCGCC CAAAAAGCCA 
GAAGGCCCCA GGAGCCACCA GCACAAGTCC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001269222.1
CDS	46..1938
Translation	MRVKLLLPAAPVLPRQHAGAFISGRDSGWPIPRQAATAPPLPDILSCQLALGAALVNVQIPLLLGQLVEVVAKYTRDHVGSFMTESQNLSTHLLILYGVQGLLTFGYLVLLSHVGERMAVDMRRALFSSLLRQDITFFDANKTGQLVSRLTTDVQEFKSSFKLVISQGLRSCTQVAGCLVSLSMLSTRLTLLLMVATPALMGVGTLMGSGLRKLSRQCQEQIARAMGVADEALGNVRTVRAFAMEQREEERYGAELEACRCRAEELGRGIALFQGLSNIAFNCMVLGTLFIGGSLVAGQQLTGGDLMSFLVASQTVQRSMANLSVLFGQVVRGLSAGARVFEYMALNPCIPLSGGCCVPKEQLRGSVTFQNVCFSYPCRPGFEVLKDFTLTLPPGKIVALVGQSGGGKTTVASLLERFYDPTAGVVMLDGRDLRTLDPSWLRGQVVGFISQEPVLFGTTIMENIRFGKLEASDEEVYTAAREANAHEFITSFPEGYNTVVGERGTTLSGGQKQRLAIARALIKQPTVLILDEATSALDAESERVVQEALDRASAGRTVLVIAHRLSTVRGAHCIVVMADGRVWEAGTHEELLKKGGLYAELIRRQALDAPRTAAPPPKKPEGPRSHQHKS

Target ORF information:

RefSeq Version	NM_001282293.1
Organism	Homo sapiens(human)
Definition	Homo sapiens ATP binding cassette subfamily B member 8 (ABCB8), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001282293.1

ORF Insert Sequence:

ATGAGGGTGA AACTGCTATT GCCGGCGGCT CCTGTTTTAC CGCGTCAGCA TGCTGGTGCA 
TTTATTTCGG GTCGGGATTC GGGGTGGCCC ATTCCCAGGC AGGCTGCTAC CGCCCCTCCG 
CTTCCAGACA TTCTCAGCTG TCAGCTGGCC TTGGGTGCGG CACTCGTGAA TGTACAGATC 
CCCCTGCTCC TGGGCCAGCT GGTAGAGGTC GTGGCCAAGT ACACAAGGGA CCACGTAGGG 
AGTTTCATGA CTGAGTCCCA GAATCTCAGC ACCCACCTGC TTATCCTCTA TGGTGTCCAG 
GGACTGCTGA CCTTCGGGTA CCTGGTGCTG CTGTCCCACG TTGGCGAGCG CATGGCTGTG 
GACATGCGGA GGGCCCTCTT CAGCTCCCTG CTCCGACAAG ACATCACCTT CTTTGACGCC 
AATAAGACAG GGCAGCTGGT GAGCCGCTTG ACAACTGACG TGCAGGAGTT TAAGTCATCC 
TTCAAGCTTG TCATCTCCCA GGGGCTGCGA AGCTGCACCC AGGTGGCAGG CTGCCTGGTG 
TCCCTGTCCA TGCTGTCGAC ACGCCTCACG CTGCTGCTGA TGGTGGCCAC ACCAGCCCTG 
ATGGGAGTGG GCACCCTGAT GGGCTCAGGC CTCCGAAAAT TGTCTCGCCA GTGTCAGGAG 
CAGATCGCCA GGGCAATGGG CGTAGCAGAC GAGGCCCTGG GCAATGTGCG GACTGTGCGT 
GCCTTCGCCA TGGAGCAACG GGAAGAGGAG CGCTATGGGG CAGAGCTGGA AGCCTGCCGC 
TGCCGGGCAG AGGAGCTGGG CCGCGGCATC GCCTTGTTCC AAGGGCTTTC CAACATCGCC 
TTCAACTGCA TGGTCTTGGG TACCCTATTT ATTGGGGGCT CCCTTGTGGC CGGACAGCAG 
CTGACAGGGG GAGACCTCAT GTCCTTCCTG GTGGCCTCCC AGACAGTGCA AAGGTCCATG 
GCCAACCTCT CTGTCCTGTT TGGGCAGGTG GTCCGGGGGC TGAGTGCAGG TGCCCGGGTC 
TTTGAGTACA TGGCCCTGAA CCCCTGCATC CCACTGTCTG GGGGCTGCTG CGTCCCCAAA 
GAGCAGCTGC GTGGCTCCGT TACATTTCAG AACGTCTGCT TCAGCTACCC CTGCCGCCCC 
GGCTTCGAGG TGCTGAAAGA CTTCACCCTG ACGCTGCCCC CTGGCAAGAT CGTGGCCCTC 
GTGGGCCAGT CTGGCGGAGG AAAGACCACC GTGGCTTCCC TGCTGGAGCG CTTCTACGAC 
CCCACGGCAG GCGTGGTGAT GCTGGATGGG CGGGACCTGC GCACCCTTGA CCCCTCCTGG 
CTCCGGGGCC AGGTTGTCGG CTTCATCAGC CAGGAGCCCG TCCTGTTTGG GACGACCATC 
ATGGAAAACA TCCGCTTTGG GAAGCTGGAA GCTTCCGATG AAGAGGTGTA CACAGCCGCC 
CGGGAAGCGA ATGCTCACGA GTTCATCACC AGCTTCCCCG AGGGCTACAA CACGGTCGTC 
GGTGAACGGG GCACTACCCT GTCTGGGGGC CAGAAGCAGC GCCTGGCCAT CGCCCGAGCC 
CTTATCAAGC AGCCCACGGT GCTGATACTG GATGAAGCTA CCAGCGCGCT GGATGCAGAG 
TCCGAGCGGG TTGTACAGGA GGCCCTGGAC CGGGCCAGTG CAGGCCGCAC GGTGCTGGTA 
ATTGCCCACC GGCTCAGCAC TGTCCGTGGG GCCCACTGCA TTGTCGTCAT GGCCGATGGC 
CGTGTCTGGG AGGCTGGGAC ACATGAAGAG CTCCTGAAGA AAGGCGGGCT ATACGCCGAG 
CTCATCCGGA GGCAGGCCCT GGATGCCCCG AGGACAGCGG CCCCACCGCC CAAAAAGCCA 
GAAGGCCCCA GGAGCCACCA GCACAAGTCC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ABCB8 ( NM_001282291.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001269220.1 Homo sapiens ATP binding cassette subfamily B member 8 (ABCB8), transcript variant 1, mRNA.

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CloneID	OHu07658
Clone ID Related Accession (Same CDS sequence)	NM_001282291.1 , NM_001282291.2
Accession Version	NM_001282291.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2208bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-23
Organism	Homo sapiens(human)
Product	ATP-binding cassette sub-family B member 8, mitochondrial isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from HY000407.1, AK002018.1, AK222911.1 and AC010973.7. On Aug 28, 2013 this sequence version replaced XM_005249935.1. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK002018.1, SRR1803615.249860.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCTGGTGC ATTTATTTCG GGTCGGGATT CGGGGTGGCC CATTCCCAGG CAGGCTGCTA 
CCGCCCCTCC GCTTCCAGAC ATTCTCAGCT GTCAGAAACA CATGGCGTAA TGGGAAAACT 
GGACAGTTAC ACAAGGCAGA AGGAGAGTAC TCTGATGGCT ACCGCAGCTC CTCCCTCCTC 
CGGGCCGTGG CCCACCTGCG GTCCCAGCTC TGGGCCCACC TCCCTCGAGC CCCCCTAGCT 
CCCAGATGGA GCCCCTCTGC CTGGTGCTGG GTTGGGGGAG CCCTGCTAGG CCCCATGGTA 
CTGAGTAAGC ATCCCCACCT CTGCCTTGTG GCCCTGTGTG AGGCAGAAGA GGCCCCTCCT 
GCCAGCTCCA CACCCCATGT CGTGGGGTCT CGCTTTAACT GGAAGCTCTT CTGGCAGTTT 
CTGCACCCCC ACCTGCTGGT CCTGGGGGTA GCCGTCGTGC TGGCCTTGGG TGCGGCACTC 
GTGAATGTAC AGATCCCCCT GCTCCTGGGC CAGCTGGTAG AGGTCGTGGC CAAGTACACA 
AGGGACCACG TAGGGAGTTT CATGACTGAG TCCCAGAATC TCAGCACCCA CCTGCTTATC 
CTCTATGGTG TCCAGGGACT GCTGACCTTC GGGTACCTGG TGCTGCTGTC CCACGTTGGC 
GAGCGCATGG CTGTGGACAT GCGGAGGGCC CTCTTCAGCT CCCTGCTCCG ACAAGACATC 
ACCTTCTTTG ACGCCAATAA GACAGGGCAG CTGGTGAGCC GCTTGACAAC TGACGTGCAG 
GAGTTTAAGT CATCCTTCAA GCTTGTCATC TCCCAGGGGC TGCGAAGCTG CACCCAGGTG 
GCAGGCTGCC TGGTGTCCCT GTCCATGCTG TCGACACGCC TCACGCTGCT GCTGATGGTG 
GCCACACCAG CCCTGATGGG AGTGGGCACC CTGATGGGCT CAGGCCTCCG AAAATTGTCT 
CGCCAGTGTC AGGAGCAGAT CGCCAGGGCA ATGGGCGTAG CAGACGAGGC CCTGGGCAAT 
GTGCGGACTG TGCGTGCCTT CGCCATGGAG CAACGGGAAG AGGAGCGCTA TGGGGCAGAG 
CTGGAAGCCT GCCGCTGCCG GGCAGAGGAG CTGGGCCGCG GCATCGCCTT GTTCCAAGGG 
CTTTCCAACA TCGCCTTCAA CTGCATGGTC TTGGGTACCC TATTTATTGG GGGCTCCCTT 
GTGGCCGGAC AGCAGCTGAC AGGGGGAGAC CTCATGTCCT TCCTGGTGGC CTCCCAGACA 
GTGCAAAGGT CCATGGCCAA CCTCTCTGTC CTGTTTGGGC AGGTGGTCCG GGGGCTGAGT 
GCAGGTGCCC GGGTCTTTGA GTACATGGCC CTGAACCCCT GCATCCCACT GTCTGGGGGC 
TGCTGCGTCC CCAAAGAGCA GCTGCGTGGC TCCGTTACAT TTCAGAACGT CTGCTTCAGC 
TACCCCTGCC GCCCCGGCTT CGAGGTGCTG AAAGACTTCA CCCTGACGCT GCCCCCTGGC 
AAGATCGTGG CCCTCGTGGG CCAGTCTGGC GGAGGAAAGA CCACCGTGGC TTCCCTGCTG 
GAGCGCTTCT ACGACCCCAC GGCAGGCGTG GTGATGCTGG ATGGGCGGGA CCTGCGCACC 
CTTGACCCCT CCTGGCTCCG GGGCCAGGTT GTCGGCTTCA TCAGCCAGGA GCCCGTCCTG 
TTTGGGACGA CCATCATGGA AAACATCCGC TTTGGGAAGC TGGAAGCTTC CGATGAAGAG 
GTGTACACAG CCGCCCGGGA AGCGAATGCT CACGAGTTCA TCACCAGCTT CCCCGAGGGC 
TACAACACGG TCGTCGGTGA ACGGGGCACT ACCCTGTCTG GGGGCCAGAA GCAGCGCCTG 
GCCATCGCCC GAGCCCTTAT CAAGCAGCCC ACGGTGCTGA TACTGGATGA AGCTACCAGC 
GCGCTGGATG CAGAGTCCGA GCGGGTTGTA CAGGAGGCCC TGGACCGGGC CAGTGCAGGC 
CGCACGGTGC TGGTAATTGC CCACCGGCTC AGCACTGTCC GTGGGGCCCA CTGCATTGTC 
GTCATGGCCG ATGGCCGTGT CTGGGAGGCT GGGACACATG AAGAGCTCCT GAAGAAAGGC 
GGGCTATACG CCGAGCTCAT CCGGAGGCAG GCCCTGGATG CCCCGAGGAC AGCGGCCCCA 
CCGCCCAAAA AGCCAGAAGG CCCCAGGAGC CACCAGCACA AGTCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001269220.1
CDS	95..2302
Translation	MLVHLFRVGIRGGPFPGRLLPPLRFQTFSAVRNTWRNGKTGQLHKAEGEYSDGYRSSSLLRAVAHLRSQLWAHLPRAPLAPRWSPSAWCWVGGALLGPMVLSKHPHLCLVALCEAEEAPPASSTPHVVGSRFNWKLFWQFLHPHLLVLGVAVVLALGAALVNVQIPLLLGQLVEVVAKYTRDHVGSFMTESQNLSTHLLILYGVQGLLTFGYLVLLSHVGERMAVDMRRALFSSLLRQDITFFDANKTGQLVSRLTTDVQEFKSSFKLVISQGLRSCTQVAGCLVSLSMLSTRLTLLLMVATPALMGVGTLMGSGLRKLSRQCQEQIARAMGVADEALGNVRTVRAFAMEQREEERYGAELEACRCRAEELGRGIALFQGLSNIAFNCMVLGTLFIGGSLVAGQQLTGGDLMSFLVASQTVQRSMANLSVLFGQVVRGLSAGARVFEYMALNPCIPLSGGCCVPKEQLRGSVTFQNVCFSYPCRPGFEVLKDFTLTLPPGKIVALVGQSGGGKTTVASLLERFYDPTAGVVMLDGRDLRTLDPSWLRGQVVGFISQEPVLFGTTIMENIRFGKLEASDEEVYTAAREANAHEFITSFPEGYNTVVGERGTTLSGGQKQRLAIARALIKQPTVLILDEATSALDAESERVVQEALDRASAGRTVLVIAHRLSTVRGAHCIVVMADGRVWEAGTHEELLKKGGLYAELIRRQALDAPRTAAPPPKKPEGPRSHQHKS

Target ORF information:

RefSeq Version	NM_001282291.1
Organism	Homo sapiens(human)
Definition	Homo sapiens ATP binding cassette subfamily B member 8 (ABCB8), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001282291.1

ORF Insert Sequence:

ATGCTGGTGC ATTTATTTCG GGTCGGGATT CGGGGTGGCC CATTCCCAGG CAGGCTGCTA 
CCGCCCCTCC GCTTCCAGAC ATTCTCAGCT GTCAGAAACA CATGGCGTAA TGGGAAAACT 
GGACAGTTAC ACAAGGCAGA AGGAGAGTAC TCTGATGGCT ACCGCAGCTC CTCCCTCCTC 
CGGGCCGTGG CCCACCTGCG GTCCCAGCTC TGGGCCCACC TCCCTCGAGC CCCCCTAGCT 
CCCAGATGGA GCCCCTCTGC CTGGTGCTGG GTTGGGGGAG CCCTGCTAGG CCCCATGGTA 
CTGAGTAAGC ATCCCCACCT CTGCCTTGTG GCCCTGTGTG AGGCAGAAGA GGCCCCTCCT 
GCCAGCTCCA CACCCCATGT CGTGGGGTCT CGCTTTAACT GGAAGCTCTT CTGGCAGTTT 
CTGCACCCCC ACCTGCTGGT CCTGGGGGTA GCCGTCGTGC TGGCCTTGGG TGCGGCACTC 
GTGAATGTAC AGATCCCCCT GCTCCTGGGC CAGCTGGTAG AGGTCGTGGC CAAGTACACA 
AGGGACCACG TAGGGAGTTT CATGACTGAG TCCCAGAATC TCAGCACCCA CCTGCTTATC 
CTCTATGGTG TCCAGGGACT GCTGACCTTC GGGTACCTGG TGCTGCTGTC CCACGTTGGC 
GAGCGCATGG CTGTGGACAT GCGGAGGGCC CTCTTCAGCT CCCTGCTCCG ACAAGACATC 
ACCTTCTTTG ACGCCAATAA GACAGGGCAG CTGGTGAGCC GCTTGACAAC TGACGTGCAG 
GAGTTTAAGT CATCCTTCAA GCTTGTCATC TCCCAGGGGC TGCGAAGCTG CACCCAGGTG 
GCAGGCTGCC TGGTGTCCCT GTCCATGCTG TCGACACGCC TCACGCTGCT GCTGATGGTG 
GCCACACCAG CCCTGATGGG AGTGGGCACC CTGATGGGCT CAGGCCTCCG AAAATTGTCT 
CGCCAGTGTC AGGAGCAGAT CGCCAGGGCA ATGGGCGTAG CAGACGAGGC CCTGGGCAAT 
GTGCGGACTG TGCGTGCCTT CGCCATGGAG CAACGGGAAG AGGAGCGCTA TGGGGCAGAG 
CTGGAAGCCT GCCGCTGCCG GGCAGAGGAG CTGGGCCGCG GCATCGCCTT GTTCCAAGGG 
CTTTCCAACA TCGCCTTCAA CTGCATGGTC TTGGGTACCC TATTTATTGG GGGCTCCCTT 
GTGGCCGGAC AGCAGCTGAC AGGGGGAGAC CTCATGTCCT TCCTGGTGGC CTCCCAGACA 
GTGCAAAGGT CCATGGCCAA CCTCTCTGTC CTGTTTGGGC AGGTGGTCCG GGGGCTGAGT 
GCAGGTGCCC GGGTCTTTGA GTACATGGCC CTGAACCCCT GCATCCCACT GTCTGGGGGC 
TGCTGCGTCC CCAAAGAGCA GCTGCGTGGC TCCGTTACAT TTCAGAACGT CTGCTTCAGC 
TACCCCTGCC GCCCCGGCTT CGAGGTGCTG AAAGACTTCA CCCTGACGCT GCCCCCTGGC 
AAGATCGTGG CCCTCGTGGG CCAGTCTGGC GGAGGAAAGA CCACCGTGGC TTCCCTGCTG 
GAGCGCTTCT ACGACCCCAC GGCAGGCGTG GTGATGCTGG ATGGGCGGGA CCTGCGCACC 
CTTGACCCCT CCTGGCTCCG GGGCCAGGTT GTCGGCTTCA TCAGCCAGGA GCCCGTCCTG 
TTTGGGACGA CCATCATGGA AAACATCCGC TTTGGGAAGC TGGAAGCTTC CGATGAAGAG 
GTGTACACAG CCGCCCGGGA AGCGAATGCT CACGAGTTCA TCACCAGCTT CCCCGAGGGC 
TACAACACGG TCGTCGGTGA ACGGGGCACT ACCCTGTCTG GGGGCCAGAA GCAGCGCCTG 
GCCATCGCCC GAGCCCTTAT CAAGCAGCCC ACGGTGCTGA TACTGGATGA AGCTACCAGC 
GCGCTGGATG CAGAGTCCGA GCGGGTTGTA CAGGAGGCCC TGGACCGGGC CAGTGCAGGC 
CGCACGGTGC TGGTAATTGC CCACCGGCTC AGCACTGTCC GTGGGGCCCA CTGCATTGTC 
GTCATGGCCG ATGGCCGTGT CTGGGAGGCT GGGACACATG AAGAGCTCCT GAAGAAAGGC 
GGGCTATACG CCGAGCTCAT CCGGAGGCAG GCCCTGGATG CCCCGAGGAC AGCGGCCCCA 
CCGCCCAAAA AGCCAGAAGG CCCCAGGAGC CACCAGCACA AGTCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ABCB8 ( NM_001282291.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001269220.1 Homo sapiens ATP binding cassette subfamily B member 8 (ABCB8), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu07658
Clone ID Related Accession (Same CDS sequence)	NM_001282291.1 , NM_001282291.2
Accession Version	NM_001282291.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2208bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-16
Organism	Homo sapiens(human)
Product	mitochondrial potassium channel ATP-binding subunit isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from HY000407.1, AK002018.1, AK222911.1 and AC010973.7. On Jun 2, 2019 this sequence version replaced NM_001282291.1. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK002018.1, SRR1803615.249860.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCTGGTGC ATTTATTTCG GGTCGGGATT CGGGGTGGCC CATTCCCAGG CAGGCTGCTA 
CCGCCCCTCC GCTTCCAGAC ATTCTCAGCT GTCAGAAACA CATGGCGTAA TGGGAAAACT 
GGACAGTTAC ACAAGGCAGA AGGAGAGTAC TCTGATGGCT ACCGCAGCTC CTCCCTCCTC 
CGGGCCGTGG CCCACCTGCG GTCCCAGCTC TGGGCCCACC TCCCTCGAGC CCCCCTAGCT 
CCCAGATGGA GCCCCTCTGC CTGGTGCTGG GTTGGGGGAG CCCTGCTAGG CCCCATGGTA 
CTGAGTAAGC ATCCCCACCT CTGCCTTGTG GCCCTGTGTG AGGCAGAAGA GGCCCCTCCT 
GCCAGCTCCA CACCCCATGT CGTGGGGTCT CGCTTTAACT GGAAGCTCTT CTGGCAGTTT 
CTGCACCCCC ACCTGCTGGT CCTGGGGGTA GCCGTCGTGC TGGCCTTGGG TGCGGCACTC 
GTGAATGTAC AGATCCCCCT GCTCCTGGGC CAGCTGGTAG AGGTCGTGGC CAAGTACACA 
AGGGACCACG TAGGGAGTTT CATGACTGAG TCCCAGAATC TCAGCACCCA CCTGCTTATC 
CTCTATGGTG TCCAGGGACT GCTGACCTTC GGGTACCTGG TGCTGCTGTC CCACGTTGGC 
GAGCGCATGG CTGTGGACAT GCGGAGGGCC CTCTTCAGCT CCCTGCTCCG ACAAGACATC 
ACCTTCTTTG ACGCCAATAA GACAGGGCAG CTGGTGAGCC GCTTGACAAC TGACGTGCAG 
GAGTTTAAGT CATCCTTCAA GCTTGTCATC TCCCAGGGGC TGCGAAGCTG CACCCAGGTG 
GCAGGCTGCC TGGTGTCCCT GTCCATGCTG TCGACACGCC TCACGCTGCT GCTGATGGTG 
GCCACACCAG CCCTGATGGG AGTGGGCACC CTGATGGGCT CAGGCCTCCG AAAATTGTCT 
CGCCAGTGTC AGGAGCAGAT CGCCAGGGCA ATGGGCGTAG CAGACGAGGC CCTGGGCAAT 
GTGCGGACTG TGCGTGCCTT CGCCATGGAG CAACGGGAAG AGGAGCGCTA TGGGGCAGAG 
CTGGAAGCCT GCCGCTGCCG GGCAGAGGAG CTGGGCCGCG GCATCGCCTT GTTCCAAGGG 
CTTTCCAACA TCGCCTTCAA CTGCATGGTC TTGGGTACCC TATTTATTGG GGGCTCCCTT 
GTGGCCGGAC AGCAGCTGAC AGGGGGAGAC CTCATGTCCT TCCTGGTGGC CTCCCAGACA 
GTGCAAAGGT CCATGGCCAA CCTCTCTGTC CTGTTTGGGC AGGTGGTCCG GGGGCTGAGT 
GCAGGTGCCC GGGTCTTTGA GTACATGGCC CTGAACCCCT GCATCCCACT GTCTGGGGGC 
TGCTGCGTCC CCAAAGAGCA GCTGCGTGGC TCCGTTACAT TTCAGAACGT CTGCTTCAGC 
TACCCCTGCC GCCCCGGCTT CGAGGTGCTG AAAGACTTCA CCCTGACGCT GCCCCCTGGC 
AAGATCGTGG CCCTCGTGGG CCAGTCTGGC GGAGGAAAGA CCACCGTGGC TTCCCTGCTG 
GAGCGCTTCT ACGACCCCAC GGCAGGCGTG GTGATGCTGG ATGGGCGGGA CCTGCGCACC 
CTTGACCCCT CCTGGCTCCG GGGCCAGGTT GTCGGCTTCA TCAGCCAGGA GCCCGTCCTG 
TTTGGGACGA CCATCATGGA AAACATCCGC TTTGGGAAGC TGGAAGCTTC CGATGAAGAG 
GTGTACACAG CCGCCCGGGA AGCGAATGCT CACGAGTTCA TCACCAGCTT CCCCGAGGGC 
TACAACACGG TCGTCGGTGA ACGGGGCACT ACCCTGTCTG GGGGCCAGAA GCAGCGCCTG 
GCCATCGCCC GAGCCCTTAT CAAGCAGCCC ACGGTGCTGA TACTGGATGA AGCTACCAGC 
GCGCTGGATG CAGAGTCCGA GCGGGTTGTA CAGGAGGCCC TGGACCGGGC CAGTGCAGGC 
CGCACGGTGC TGGTAATTGC CCACCGGCTC AGCACTGTCC GTGGGGCCCA CTGCATTGTC 
GTCATGGCCG ATGGCCGTGT CTGGGAGGCT GGGACACATG AAGAGCTCCT GAAGAAAGGC 
GGGCTATACG CCGAGCTCAT CCGGAGGCAG GCCCTGGATG CCCCGAGGAC AGCGGCCCCA 
CCGCCCAAAA AGCCAGAAGG CCCCAGGAGC CACCAGCACA AGTCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001269220.1
CDS	67..2274
Translation	MLVHLFRVGIRGGPFPGRLLPPLRFQTFSAVRNTWRNGKTGQLHKAEGEYSDGYRSSSLLRAVAHLRSQLWAHLPRAPLAPRWSPSAWCWVGGALLGPMVLSKHPHLCLVALCEAEEAPPASSTPHVVGSRFNWKLFWQFLHPHLLVLGVAVVLALGAALVNVQIPLLLGQLVEVVAKYTRDHVGSFMTESQNLSTHLLILYGVQGLLTFGYLVLLSHVGERMAVDMRRALFSSLLRQDITFFDANKTGQLVSRLTTDVQEFKSSFKLVISQGLRSCTQVAGCLVSLSMLSTRLTLLLMVATPALMGVGTLMGSGLRKLSRQCQEQIARAMGVADEALGNVRTVRAFAMEQREEERYGAELEACRCRAEELGRGIALFQGLSNIAFNCMVLGTLFIGGSLVAGQQLTGGDLMSFLVASQTVQRSMANLSVLFGQVVRGLSAGARVFEYMALNPCIPLSGGCCVPKEQLRGSVTFQNVCFSYPCRPGFEVLKDFTLTLPPGKIVALVGQSGGGKTTVASLLERFYDPTAGVVMLDGRDLRTLDPSWLRGQVVGFISQEPVLFGTTIMENIRFGKLEASDEEVYTAAREANAHEFITSFPEGYNTVVGERGTTLSGGQKQRLAIARALIKQPTVLILDEATSALDAESERVVQEALDRASAGRTVLVIAHRLSTVRGAHCIVVMADGRVWEAGTHEELLKKGGLYAELIRRQALDAPRTAAPPPKKPEGPRSHQHKS

Target ORF information:

RefSeq Version	NM_001282291.2
Organism	Homo sapiens(human)
Definition	Homo sapiens ATP binding cassette subfamily B member 8 (ABCB8), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001282291.2

ORF Insert Sequence:

ATGCTGGTGC ATTTATTTCG GGTCGGGATT CGGGGTGGCC CATTCCCAGG CAGGCTGCTA 
CCGCCCCTCC GCTTCCAGAC ATTCTCAGCT GTCAGAAACA CATGGCGTAA TGGGAAAACT 
GGACAGTTAC ACAAGGCAGA AGGAGAGTAC TCTGATGGCT ACCGCAGCTC CTCCCTCCTC 
CGGGCCGTGG CCCACCTGCG GTCCCAGCTC TGGGCCCACC TCCCTCGAGC CCCCCTAGCT 
CCCAGATGGA GCCCCTCTGC CTGGTGCTGG GTTGGGGGAG CCCTGCTAGG CCCCATGGTA 
CTGAGTAAGC ATCCCCACCT CTGCCTTGTG GCCCTGTGTG AGGCAGAAGA GGCCCCTCCT 
GCCAGCTCCA CACCCCATGT CGTGGGGTCT CGCTTTAACT GGAAGCTCTT CTGGCAGTTT 
CTGCACCCCC ACCTGCTGGT CCTGGGGGTA GCCGTCGTGC TGGCCTTGGG TGCGGCACTC 
GTGAATGTAC AGATCCCCCT GCTCCTGGGC CAGCTGGTAG AGGTCGTGGC CAAGTACACA 
AGGGACCACG TAGGGAGTTT CATGACTGAG TCCCAGAATC TCAGCACCCA CCTGCTTATC 
CTCTATGGTG TCCAGGGACT GCTGACCTTC GGGTACCTGG TGCTGCTGTC CCACGTTGGC 
GAGCGCATGG CTGTGGACAT GCGGAGGGCC CTCTTCAGCT CCCTGCTCCG ACAAGACATC 
ACCTTCTTTG ACGCCAATAA GACAGGGCAG CTGGTGAGCC GCTTGACAAC TGACGTGCAG 
GAGTTTAAGT CATCCTTCAA GCTTGTCATC TCCCAGGGGC TGCGAAGCTG CACCCAGGTG 
GCAGGCTGCC TGGTGTCCCT GTCCATGCTG TCGACACGCC TCACGCTGCT GCTGATGGTG 
GCCACACCAG CCCTGATGGG AGTGGGCACC CTGATGGGCT CAGGCCTCCG AAAATTGTCT 
CGCCAGTGTC AGGAGCAGAT CGCCAGGGCA ATGGGCGTAG CAGACGAGGC CCTGGGCAAT 
GTGCGGACTG TGCGTGCCTT CGCCATGGAG CAACGGGAAG AGGAGCGCTA TGGGGCAGAG 
CTGGAAGCCT GCCGCTGCCG GGCAGAGGAG CTGGGCCGCG GCATCGCCTT GTTCCAAGGG 
CTTTCCAACA TCGCCTTCAA CTGCATGGTC TTGGGTACCC TATTTATTGG GGGCTCCCTT 
GTGGCCGGAC AGCAGCTGAC AGGGGGAGAC CTCATGTCCT TCCTGGTGGC CTCCCAGACA 
GTGCAAAGGT CCATGGCCAA CCTCTCTGTC CTGTTTGGGC AGGTGGTCCG GGGGCTGAGT 
GCAGGTGCCC GGGTCTTTGA GTACATGGCC CTGAACCCCT GCATCCCACT GTCTGGGGGC 
TGCTGCGTCC CCAAAGAGCA GCTGCGTGGC TCCGTTACAT TTCAGAACGT CTGCTTCAGC 
TACCCCTGCC GCCCCGGCTT CGAGGTGCTG AAAGACTTCA CCCTGACGCT GCCCCCTGGC 
AAGATCGTGG CCCTCGTGGG CCAGTCTGGC GGAGGAAAGA CCACCGTGGC TTCCCTGCTG 
GAGCGCTTCT ACGACCCCAC GGCAGGCGTG GTGATGCTGG ATGGGCGGGA CCTGCGCACC 
CTTGACCCCT CCTGGCTCCG GGGCCAGGTT GTCGGCTTCA TCAGCCAGGA GCCCGTCCTG 
TTTGGGACGA CCATCATGGA AAACATCCGC TTTGGGAAGC TGGAAGCTTC CGATGAAGAG 
GTGTACACAG CCGCCCGGGA AGCGAATGCT CACGAGTTCA TCACCAGCTT CCCCGAGGGC 
TACAACACGG TCGTCGGTGA ACGGGGCACT ACCCTGTCTG GGGGCCAGAA GCAGCGCCTG 
GCCATCGCCC GAGCCCTTAT CAAGCAGCCC ACGGTGCTGA TACTGGATGA AGCTACCAGC 
GCGCTGGATG CAGAGTCCGA GCGGGTTGTA CAGGAGGCCC TGGACCGGGC CAGTGCAGGC 
CGCACGGTGC TGGTAATTGC CCACCGGCTC AGCACTGTCC GTGGGGCCCA CTGCATTGTC 
GTCATGGCCG ATGGCCGTGT CTGGGAGGCT GGGACACATG AAGAGCTCCT GAAGAAAGGC 
GGGCTATACG CCGAGCTCAT CCGGAGGCAG GCCCTGGATG CCCCGAGGAC AGCGGCCCCA 
CCGCCCAAAA AGCCAGAAGG CCCCAGGAGC CACCAGCACA AGTCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Profiling of ABC transporters during active ulcerative colitis and in vitro effect of inflammatory modulators.
Digestive diseases and sciences58(8)2282-92(2013 Aug)
Verma N,Ahuja V,Paul J

Disruption of ATP-binding cassette B8 in mice leads to cardiomyopathy through a decrease in mitochondrial iron export.
Proceedings of the National Academy of Sciences of the United States of America109(11)4152-7(2012 Mar)
Ichikawa Y,Bayeva M,Ghanefar M,Potini V,Sun L,Mutharasan RK,Wu R,Khechaduri A,Jairaj Naik T,Ardehali H

Mithramycin A suppresses expression of the human melanoma-associated gene ABCB8.
Molecular genetics and genomics : MGG285(1)57-65(2011 Jan)
Sachrajda I,Ratajewski M

Mitochondrial ABC proteins in health and disease.
Biochimica et biophysica acta1787(6)681-90(2009 Jun)
Zutz A,Gompf S,Sch?gger H,Tamp? R

Exclusion of ABCB8 and ABCB10 as cancer candidate genes in acute myeloid leukemia.
Leukemia23(5)1000-2(2009 May)
Tang L,Bergevoet SM,Franssen LE,de Witte T,Jansen JH,Raymakers RA,van der Reijden BA

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ABCB8 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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