Amer1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Amer1
Entrez Gene ID	72345
Full Name	APC membrane recruitment 1
Synonyms	2810002O09Rik,AW492303,Fam123b,Wtx
General protein information	Preferred Names APC membrane recruitment 1 Names APC membrane recruitment protein 1 family with sequence similarity 123, member B protein Fam123b
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: X Map Location: X\|X C3

mRNA and Protein(s)

mRNA	Protein	Name
NM_175179.4	NP_780388.2	APC membrane recruitment protein 1

Pathways from BioSystems

Homologies

Gallus gallus (chicken)	FAM123B	XP_420290.4
Canis lupus familiaris (dog)	AMER1	XP_005641471.1
Rattus norvegicus (Norway rat)	Amer1	NP_001102790.1
Pan troglodytes (chimpanzee)	FAM123B	XP_003317544.1
Bos taurus (cattle)	FAM123B	XP_005228330.1
Xenopus tropicalis (tropical clawed frog)	amer1	XP_004915814.1
Mus musculus (house mouse)	Amer1	NP_780388.2
Homo sapiens (human)	AMER1	NP_689637.3
	LOC707700	XP_001096922.2

Gene Ontology
Bibliography

Related articles in PubMed

Genetic and molecular insights into genotype-phenotype relationships in osteopathia striata with cranial sclerosis (OSCS) through the analysis of novel mouse Wtx mutant alleles.
Comai G, Boutet A, Tanneberger K, Massa F, Rocha AS, Charlet A, Panzolini C, Motamedi FJ, Brommage R, Hans W, Funck-Brentano T, de Angelis MH, Hartmann C, Cohen-Solal M, Behrens J, Schedl A
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research(2018 Jan)

The WTX Tumor Suppressor Interacts with the Transcriptional Corepressor TRIM28.
Kim WJ, Wittner BS, Amzallag A, Brannigan BW, Ting DT, Ramaswamy S, Maheswaran S, Haber DA
The Journal of biological chemistry290(23)14381-90(2015 Jun)

The WTX tumor suppressor regulates mesenchymal progenitor cell fate specification.
Moisan A, Rivera MN, Lotinun S, Akhavanfard S, Coffman EJ, Cook EB, Stoykova S, Mukherjee S, Schoonmaker JA, Burger A, Kim WJ, Kronenberg HM, Baron R, Haber DA, Bardeesy N
Developmental cell20(5)583-596(2011 May)

Expression patterns of the Wtx/Amer gene family during mouse embryonic development.
Comai G, Boutet A, Neirijnck Y, Schedl A
Developmental dynamics : an official publication of the American Association of Anatomists239(6)1867-78(2010 Jun)

Germline mutations in WTX cause a sclerosing skeletal dysplasia but do not predispose to tumorigenesis.
Jenkins ZA, van Kogelenberg M, Morgan T, Jeffs A, Fukuzawa R, Pearl E, Thaller C, Hing AV, Porteous ME, Garcia-Mi?aur S, Bohring A, Lacombe D, Stewart F, Fiskerstrand T, Bindoff L, Berland S, Ad?s LC, Tchan M, David A, Wilson LC, Hennekam RC, Donnai D, Mansour S, Cormier-Daire V, Robertson SP
Nature genetics41(1)95-100(2009 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

WTX stabilized chromatin binding by TRIM28 and contributed to transcriptional repression of repetitive sequences by TRIM28 in mouse embryonic stem cells.
Title: The WTX Tumor Suppressor Interacts with the Transcriptional Corepressor TRIM28.

The constellation of anomalies in Wtx null mice suggests that this tumor suppressor broadly regulates mesenchymal progenitor cells in multiple tissues.
Title: The WTX tumor suppressor regulates mesenchymal progenitor cell fate specification.

The observed phenotypic discordance dependent upon whether a mutation is germline or occurs somatically suggests the existence of temporal or spatial constraints on the action of WTX during tumorigenesis.
Title: Germline mutations in WTX cause a sclerosing skeletal dysplasia but do not predispose to tumorigenesis.

The following Amer1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Amer1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu04967	NM_175179.4 Latest version!	Mus musculus APC membrane recruitment 1 (Amer1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$559.30 $799.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Amer1 ( NM_175179.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_780388.2 Mus musculus APC membrane recruitment 1 (Amer1), mRNA.

Price & Availability↑

CloneID	OMu04967
Clone ID Related Accession (Same CDS sequence)	NM_175179.4
Accession Version	NM_175179.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3399bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-26
Organism	Mus musculus(house mouse)
Product	APC membrane recruitment protein 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CK392507.1, AL671765.6 and CD645252.1. On Oct 30, 2007 this sequence version replaced NM_175179.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: CK392507.1, AK049774.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849380, SAMN00849382 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGAGTC AACAGGATGA AGCTGTTCAA ACCAAAGGAG CATCAACTTC TAGCGATGCC 
CAAGACCAGG GAGCTGAAAA GGGAGCCAAG AATAAGACAA CTGAGGCAAC AGAAGGACCA 
ACATCAGAGC CTCCCTTATC AGGCCCAGGT AGGCTGAAGA AAACTGCCAT GAAACTCTTT 
GGTGGCAAGA AGGGAATCTG TACTCTGCCT AGTTTCTTTG GGGGTGGACG AAGCAAAGGT 
TCTGGGAAAG TCAGCTCTAA GAAAAGTCTA AACAAGAGTA AGACTCACGA TGGTCTAAGT 
GAAGCGTCTC AGGGACCTGA AGATGTTGTC ATTGAAGAAA CAGACCTCTC TACACCTTTG 
TCCAAGTCAT CTGCTCAATT TCCTAGCTCC CAGAGTGCCA ATGGAGCGTT GGAGATAGGC 
TCTAAACATA AGACATCTGG GACTGAAGCC ATAGAAAAAG CTGGAGTTGA GAAGGTACCC 
TCTGTGCACA AGCCGAAGAA AAGCCTAAAA AGCTTCTTTA GCAGTATCCG CCGTCACCGG 
AAGGGCAAGA CTTCTGGGGC TGACCAAAGT GTGCCAGGGG CCAAGGAACT TGAGGGGGCA 
AGAACCAGGT CTCATGAGCA TGTGAGTTCA ATCTCTCTGC CCAGCTCTGA GGAGATATTC 
CGAGACACTA GAAAGGAAAA TGCCAAACCC CAGGATGCCC CTGGACCAAA AATGTCTCCA 
GCACAAGTAC ATTTTTCACC AACTACTGAG AAGGCAGCTT GTAAAAATCC AGAAAAACTC 
ACAAGGACCT GTGCCTCAGA GTTCATGCAG CCCAAGCCTG TTCTTGAAGG TGGTAGTCTA 
GAGGAGCCCC ACACTTCAGA AACAGAAGGA AAAGTGGTGG CAGGAGAAGT AAACCCACCC 
AATGGCCCTG TTGGGGATCA GCTAAGCCTC TTGTTTGGGG ATGTTACATC GCTAAAAAGC 
TTTGACTCAC TGACAGGTTG TGGTGACATT ATAGCAGAAC AGGACATGGA CAGCATGACA 
GATAGCATGG CCTCTGGTGG CCAGAGGGCC AACCGAGATG GGACCAAGCG AAGTTCCTGC 
TTGGTAACCT ACCAAGGAGG TGGGGAGGAG ATGGCCTTGC CAGATGATGA TGACAATGAT 
GATGAAGAAG AAGAAGAAGA AGAAGAAGAA GAAGAAGAAG AAGAAGAAGA AGAAGAAGAA 
GAAGAAGAAG AAGAAGAAGA AGAAGAATTA TTAGAGGATG AAGAGGAGGT TAAGGATGGA 
GAGGAAAATG ATGACTTAGA GTATCTGTGG GCAAGTGCCC AGATATACCC AAGATTTAAT 
ATGAATCTGG GCTACCATAC TGCTATATCT CCCAGCCACC AGGGCTACAT GCTTCTTGAC 
CCAGTTCAGT CTTATCCTAA TCTAGGCCTT GGAGAACTTT TGACACCTCA GAGCGACCAG 
CAAGAGTCTG CTCCCAATAG TGATGAAGGT TATTATGACT CTACCACACC AGGATTTGAG 
GATGATTCAG GTGAGGCTCT GGGACTTGCC CACAGGGATT GTCTACCCAG GGACAGCTAT 
AGTGGTGATG CGCTATATGA GTTCTATGAG CCAGATGACA GTCTTGAGCA CTCCCCACCT 
GGGGATGACT GCCTATATGA CCTCCGTGGA CGCAACTCAG AGATGTTGGA TCCTTTCTTG 
AACTTGGAGC CCTTTTCTTC TCGGCCACCT GGGGCAATGG AAACCGAGGA AGAACGGCTA 
GTGACCATCC AGAAGCAGTT GCTATACTGG GAACTTCGCC GGGAGCAGCG TGAGGCTCAA 
GAGGCATGTG CCAGAGAGGC TCATGCCAGA GAAGCTTATG CCCGAGACAC CCATACTCGG 
GAATCTTATG GCAGAAATGT CCGAGCCCGA GAAACTCAGG CCTTAGAGGC TCATTCTCAA 
GAGGGTCGAG TCCAAGAGAC CAAGGTACGG CAGGAGAAGC CTGCCTTGGA GTATCAGATG 
AGGCCCTTAG GTCCCTCAGT GATGGGTCTG GTGGCAGGGA CATCAGGAGG TTCTCAGACT 
TCTCACCGGG GAACCACTTC AGCTTTCCCT GCTACTTCTA GCAGTGAGCC AGACTGGAGG 
GATTTCCGTC CTCTGGAGAA GCGTTTTGAG GGGACTTGTT CCAAAAAAGA TCAAAGTACT 
TGTTTAATGC AGCTCTTCCA GAGTGATGCC ATGTTTGAGC CAGACATGCA AGAAGCAAAT 
TTTGGAGGCT CACCCAGGAA GGCGTACCCT AGTTACTCAC CCCCTGAGGA GCCAGAGGAA 
GAAGAAGAGG AGAAGGAAGG GAATGCCACT GTGAGTTTCT CACAGGCCCT AGTAGAGTTC 
ACCAGCAATG GAAACCTTTT TACCAGCATG TCCTACAGCT CTGATTCTGA CTCATCCTTC 
ACTCAAAACC TCCCTGAGCT GCCCCCCATG GTCACCTTTG ATATTGCTGA CGTGGAACGA 
GATGGAGAAG GCAAGTGTGA AGAGAATCCT GAGTTCAACA ATGACGAAGA TCTTACAGCC 
TCCTTGGAAG CTTTTGAGCT GGGTTATTAC CACAAACATG CCTTCAACAG CTATCACAGT 
CGGTTCTACC AAGGCCTGCC CTGGGGAGTT AGCAGCCTCC CTCGATACTT AGGACTCCCC 
GGAGTCCACC CTCGACCTCC TCCTGCTGCA ATGGCACTCA ATAGGAGAAG CCGTTCCCTT 
GACAATGCAG AGTCTCTGGA GCTGGAGCTC TCCAGTTCTC ACCTAGCCCA GGGTTACATG 
GAGTCTGATG AGCTCCAGGC CCACCAGGAA GATTCAGATG AAGAAGGTGA AGAAGAGGAA 
GGAGAATGGG GTCGGGATAG TCCCTTGTCT CTCTACACTG AACCTCCAGG GGTCTATGAC 
TGGCCTCCCT GGGCTCACTG TCCTCTTCCA GTGGGGCCAG GTCTTGCTTG GATGAGCCCT 
AATCAGTTGT ATGAGCCTTT CAATCAGTCT TCCTATGTGC AGGCAACCTG TTGTGTACCT 
CCTGTGGCAA TGCCAGTGTC AGTGCCAGGA AGAACACCTG GAGACTCTGT GTCTCAGCTA 
GCTCGACCTT CGCACCTACC CCTGCCCATG GGCCCTTGCT ATAACCTTCA ATCACAGGCC 
TCCCAGAGTG GGAGGGCCAA GCCTCGGGAT GTACTGCTGC CTGTAGATGA GCCCAGTTGC 
TCTTCCATTT CTGGAGCCAA CTCTCAGTCT CAAGCCAAGC CTGTAGGTAT CACCCATGGT 
ATCCCTCAGC TGCCCAGGGT GCGGCCTGAA CCCTTCCAGC TTCAACCCAA TCACTATCGA 
GCTTCCAACC TTGACCTGTC AAAGGAGAGG GGTGAGCAAG GTGCCTCTCT CTCTACCAGC 
TACTCCTCTA CTGCCATGAA TGGAAACCTA GCCAAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_780388.2
CDS	272..3670
Translation	MESQQDEAVQTKGASTSSDAQDQGAEKGAKNKTTEATEGPTSEPPLSGPGRLKKTAMKLFGGKKGICTLPSFFGGGRSKGSGKVSSKKSLNKSKTHDGLSEASQGPEDVVIEETDLSTPLSKSSAQFPSSQSANGALEIGSKHKTSGTEAIEKAGVEKVPSVHKPKKSLKSFFSSIRRHRKGKTSGADQSVPGAKELEGARTRSHEHVSSISLPSSEEIFRDTRKENAKPQDAPGPKMSPAQVHFSPTTEKAACKNPEKLTRTCASEFMQPKPVLEGGSLEEPHTSETEGKVVAGEVNPPNGPVGDQLSLLFGDVTSLKSFDSLTGCGDIIAEQDMDSMTDSMASGGQRANRDGTKRSSCLVTYQGGGEEMALPDDDDNDDEEEEEEEEEEEEEEEEEEEEEEEEEEEELLEDEEEVKDGEENDDLEYLWASAQIYPRFNMNLGYHTAISPSHQGYMLLDPVQSYPNLGLGELLTPQSDQQESAPNSDEGYYDSTTPGFEDDSGEALGLAHRDCLPRDSYSGDALYEFYEPDDSLEHSPPGDDCLYDLRGRNSEMLDPFLNLEPFSSRPPGAMETEEERLVTIQKQLLYWELRREQREAQEACAREAHAREAYARDTHTRESYGRNVRARETQALEAHSQEGRVQETKVRQEKPALEYQMRPLGPSVMGLVAGTSGGSQTSHRGTTSAFPATSSSEPDWRDFRPLEKRFEGTCSKKDQSTCLMQLFQSDAMFEPDMQEANFGGSPRKAYPSYSPPEEPEEEEEEKEGNATVSFSQALVEFTSNGNLFTSMSYSSDSDSSFTQNLPELPPMVTFDIADVERDGEGKCEENPEFNNDEDLTASLEAFELGYYHKHAFNSYHSRFYQGLPWGVSSLPRYLGLPGVHPRPPPAAMALNRRSRSLDNAESLELELSSSHLAQGYMESDELQAHQEDSDEEGEEEEGEWGRDSPLSLYTEPPGVYDWPPWAHCPLPVGPGLAWMSPNQLYEPFNQSSYVQATCCVPPVAMPVSVPGRTPGDSVSQLARPSHLPLPMGPCYNLQSQASQSGRAKPRDVLLPVDEPSCSSISGANSQSQAKPVGITHGIPQLPRVRPEPFQLQPNHYRASNLDLSKERGEQGASLSTSYSSTAMNGNLAK

Target ORF information:

RefSeq Version	NM_175179.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus APC membrane recruitment 1 (Amer1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_175179.4

ORF Insert Sequence:

ATGGAGAGTC AACAGGATGA AGCTGTTCAA ACCAAAGGAG CATCAACTTC TAGCGATGCC 
CAAGACCAGG GAGCTGAAAA GGGAGCCAAG AATAAGACAA CTGAGGCAAC AGAAGGACCA 
ACATCAGAGC CTCCCTTATC AGGCCCAGGT AGGCTGAAGA AAACTGCCAT GAAACTCTTT 
GGTGGCAAGA AGGGAATCTG TACTCTGCCT AGTTTCTTTG GGGGTGGACG AAGCAAAGGT 
TCTGGGAAAG TCAGCTCTAA GAAAAGTCTA AACAAGAGTA AGACTCACGA TGGTCTAAGT 
GAAGCGTCTC AGGGACCTGA AGATGTTGTC ATTGAAGAAA CAGACCTCTC TACACCTTTG 
TCCAAGTCAT CTGCTCAATT TCCTAGCTCC CAGAGTGCCA ATGGAGCGTT GGAGATAGGC 
TCTAAACATA AGACATCTGG GACTGAAGCC ATAGAAAAAG CTGGAGTTGA GAAGGTACCC 
TCTGTGCACA AGCCGAAGAA AAGCCTAAAA AGCTTCTTTA GCAGTATCCG CCGTCACCGG 
AAGGGCAAGA CTTCTGGGGC TGACCAAAGT GTGCCAGGGG CCAAGGAACT TGAGGGGGCA 
AGAACCAGGT CTCATGAGCA TGTGAGTTCA ATCTCTCTGC CCAGCTCTGA GGAGATATTC 
CGAGACACTA GAAAGGAAAA TGCCAAACCC CAGGATGCCC CTGGACCAAA AATGTCTCCA 
GCACAAGTAC ATTTTTCACC AACTACTGAG AAGGCAGCTT GTAAAAATCC AGAAAAACTC 
ACAAGGACCT GTGCCTCAGA GTTCATGCAG CCCAAGCCTG TTCTTGAAGG TGGTAGTCTA 
GAGGAGCCCC ACACTTCAGA AACAGAAGGA AAAGTGGTGG CAGGAGAAGT AAACCCACCC 
AATGGCCCTG TTGGGGATCA GCTAAGCCTC TTGTTTGGGG ATGTTACATC GCTAAAAAGC 
TTTGACTCAC TGACAGGTTG TGGTGACATT ATAGCAGAAC AGGACATGGA CAGCATGACA 
GATAGCATGG CCTCTGGTGG CCAGAGGGCC AACCGAGATG GGACCAAGCG AAGTTCCTGC 
TTGGTAACCT ACCAAGGAGG TGGGGAGGAG ATGGCCTTGC CAGATGATGA TGACAATGAT 
GATGAAGAAG AAGAAGAAGA AGAAGAAGAA GAAGAAGAAG AAGAAGAAGA AGAAGAAGAA 
GAAGAAGAAG AAGAAGAAGA AGAAGAATTA TTAGAGGATG AAGAGGAGGT TAAGGATGGA 
GAGGAAAATG ATGACTTAGA GTATCTGTGG GCAAGTGCCC AGATATACCC AAGATTTAAT 
ATGAATCTGG GCTACCATAC TGCTATATCT CCCAGCCACC AGGGCTACAT GCTTCTTGAC 
CCAGTTCAGT CTTATCCTAA TCTAGGCCTT GGAGAACTTT TGACACCTCA GAGCGACCAG 
CAAGAGTCTG CTCCCAATAG TGATGAAGGT TATTATGACT CTACCACACC AGGATTTGAG 
GATGATTCAG GTGAGGCTCT GGGACTTGCC CACAGGGATT GTCTACCCAG GGACAGCTAT 
AGTGGTGATG CGCTATATGA GTTCTATGAG CCAGATGACA GTCTTGAGCA CTCCCCACCT 
GGGGATGACT GCCTATATGA CCTCCGTGGA CGCAACTCAG AGATGTTGGA TCCTTTCTTG 
AACTTGGAGC CCTTTTCTTC TCGGCCACCT GGGGCAATGG AAACCGAGGA AGAACGGCTA 
GTGACCATCC AGAAGCAGTT GCTATACTGG GAACTTCGCC GGGAGCAGCG TGAGGCTCAA 
GAGGCATGTG CCAGAGAGGC TCATGCCAGA GAAGCTTATG CCCGAGACAC CCATACTCGG 
GAATCTTATG GCAGAAATGT CCGAGCCCGA GAAACTCAGG CCTTAGAGGC TCATTCTCAA 
GAGGGTCGAG TCCAAGAGAC CAAGGTACGG CAGGAGAAGC CTGCCTTGGA GTATCAGATG 
AGGCCCTTAG GTCCCTCAGT GATGGGTCTG GTGGCAGGGA CATCAGGAGG TTCTCAGACT 
TCTCACCGGG GAACCACTTC AGCTTTCCCT GCTACTTCTA GCAGTGAGCC AGACTGGAGG 
GATTTCCGTC CTCTGGAGAA GCGTTTTGAG GGGACTTGTT CCAAAAAAGA TCAAAGTACT 
TGTTTAATGC AGCTCTTCCA GAGTGATGCC ATGTTTGAGC CAGACATGCA AGAAGCAAAT 
TTTGGAGGCT CACCCAGGAA GGCGTACCCT AGTTACTCAC CCCCTGAGGA GCCAGAGGAA 
GAAGAAGAGG AGAAGGAAGG GAATGCCACT GTGAGTTTCT CACAGGCCCT AGTAGAGTTC 
ACCAGCAATG GAAACCTTTT TACCAGCATG TCCTACAGCT CTGATTCTGA CTCATCCTTC 
ACTCAAAACC TCCCTGAGCT GCCCCCCATG GTCACCTTTG ATATTGCTGA CGTGGAACGA 
GATGGAGAAG GCAAGTGTGA AGAGAATCCT GAGTTCAACA ATGACGAAGA TCTTACAGCC 
TCCTTGGAAG CTTTTGAGCT GGGTTATTAC CACAAACATG CCTTCAACAG CTATCACAGT 
CGGTTCTACC AAGGCCTGCC CTGGGGAGTT AGCAGCCTCC CTCGATACTT AGGACTCCCC 
GGAGTCCACC CTCGACCTCC TCCTGCTGCA ATGGCACTCA ATAGGAGAAG CCGTTCCCTT 
GACAATGCAG AGTCTCTGGA GCTGGAGCTC TCCAGTTCTC ACCTAGCCCA GGGTTACATG 
GAGTCTGATG AGCTCCAGGC CCACCAGGAA GATTCAGATG AAGAAGGTGA AGAAGAGGAA 
GGAGAATGGG GTCGGGATAG TCCCTTGTCT CTCTACACTG AACCTCCAGG GGTCTATGAC 
TGGCCTCCCT GGGCTCACTG TCCTCTTCCA GTGGGGCCAG GTCTTGCTTG GATGAGCCCT 
AATCAGTTGT ATGAGCCTTT CAATCAGTCT TCCTATGTGC AGGCAACCTG TTGTGTACCT 
CCTGTGGCAA TGCCAGTGTC AGTGCCAGGA AGAACACCTG GAGACTCTGT GTCTCAGCTA 
GCTCGACCTT CGCACCTACC CCTGCCCATG GGCCCTTGCT ATAACCTTCA ATCACAGGCC 
TCCCAGAGTG GGAGGGCCAA GCCTCGGGAT GTACTGCTGC CTGTAGATGA GCCCAGTTGC 
TCTTCCATTT CTGGAGCCAA CTCTCAGTCT CAAGCCAAGC CTGTAGGTAT CACCCATGGT 
ATCCCTCAGC TGCCCAGGGT GCGGCCTGAA CCCTTCCAGC TTCAACCCAA TCACTATCGA 
GCTTCCAACC TTGACCTGTC AAAGGAGAGG GGTGAGCAAG GTGCCTCTCT CTCTACCAGC 
TACTCCTCTA CTGCCATGAA TGGAAACCTA GCCAAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Genetic and molecular insights into genotype-phenotype relationships in osteopathia striata with cranial sclerosis (OSCS) through the analysis of novel mouse Wtx mutant alleles.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research(2018 Jan)
Comai G,Boutet A,Tanneberger K,Massa F,Rocha AS,Charlet A,Panzolini C,Motamedi FJ,Brommage R,Hans W,Funck-Brentano T,de Angelis MH,Hartmann C,Cohen-Solal M,Behrens J,Schedl A

The WTX Tumor Suppressor Interacts with the Transcriptional Corepressor TRIM28.
The Journal of biological chemistry290(23)14381-90(2015 Jun)
Kim WJ,Wittner BS,Amzallag A,Brannigan BW,Ting DT,Ramaswamy S,Maheswaran S,Haber DA

The WTX tumor suppressor regulates mesenchymal progenitor cell fate specification.
Developmental cell20(5)583-596(2011 May)
Moisan A,Rivera MN,Lotinun S,Akhavanfard S,Coffman EJ,Cook EB,Stoykova S,Mukherjee S,Schoonmaker JA,Burger A,Kim WJ,Kronenberg HM,Baron R,Haber DA,Bardeesy N

Expression patterns of the Wtx/Amer gene family during mouse embryonic development.
Developmental dynamics : an official publication of the American Association of Anatomists239(6)1867-78(2010 Jun)
Comai G,Boutet A,Neirijnck Y,Schedl A

Germline mutations in WTX cause a sclerosing skeletal dysplasia but do not predispose to tumorigenesis.
Nature genetics41(1)95-100(2009 Jan)
Jenkins ZA,van Kogelenberg M,Morgan T,Jeffs A,Fukuzawa R,Pearl E,Thaller C,Hing AV,Porteous ME,Garcia-Mi?aur S,Bohring A,Lacombe D,Stewart F,Fiskerstrand T,Bindoff L,Berland S,Ad?s LC,Tchan M,David A,Wilson LC,Hennekam RC,Donnai D,Mansour S,Cormier-Daire V,Robertson SP

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Amer1 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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