Rnaseh2a cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Rnaseh2a
Entrez Gene ID	69724
Full Name	ribonuclease H2, large subunit
Synonyms	2400006P09Rik,RNASEHI,RNHIA,RNHL
General protein information	Preferred Names ribonuclease H2, large subunit Names ribonuclease H2 subunit A RNase H2 subunit A RNase HI large subunit ribonuclease HI large subunit ribonuclease HI subunit A
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 8 Map Location: 8\|8 C3

mRNA and Protein(s)

mRNA	Protein	Name
XM_011248498.3	XP_011246800.1	ribonuclease H2 subunit A isoform X1
NM_027187.4	NP_081463.1	ribonuclease H2 subunit A isoform 1
XM_011248498.2	XP_011246800.1	ribonuclease H2 subunit A isoform X1
NM_001364370.1	NP_001351299.1	ribonuclease H2 subunit A isoform 2
XM_011248497.2	XP_011246799.1	ribonuclease H2 subunit A isoform X1
NM_027187.3	NP_081463.1	ribonuclease H2 subunit A
XM_011248497.3	XP_011246799.1	ribonuclease H2 subunit A isoform X1

Pathways from BioSystems

Homologies

Danio rerio (zebrafish)	rnaseh2a	NP_956520.2
Caenorhabditis elegans (roundworm)	rnh-2	NP_495796.1
Saccharomyces cerevisiae (baker's yeast)	RNH201	NP_014327.1
Eremothecium gossypii	AGOS_AER363W	NP_985219.2
Homo sapiens (human)	RNASEH2A	NP_006388.2
Canis lupus familiaris (dog)	RNASEH2A	XP_003639769.1
Drosophila melanogaster (fruit fly)	CG13690	NP_608521.1
Kluyveromyces lactis	KLLA0F04774g	XP_455296.1
Magnaporthe oryzae (rice blast fungus)	MGG_06959	XP_003709705.1
	RNASEH2A	XP_001109423.1
Bos taurus (cattle)	RNASEH2A	NP_001033623.1
Schizosaccharomyces pombe (fission yeast)	rnh201	NP_593684.1
Arabidopsis thaliana (thale cress)	AT2G25100	NP_565584.1
Pan troglodytes (chimpanzee)	RNASEH2A	XP_512415.1
Mus musculus (house mouse)	Rnaseh2a	NP_081463.1
Rattus norvegicus (Norway rat)	Rnaseh2a	NP_001013252.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP007741	XP_317779.3
Neurospora crassa	NCU09608	XP_963372.2
Oryza sativa (rice)	Os11g0153900	NP_001065783.1
Xenopus tropicalis (tropical clawed frog)	rnaseh2a	NP_989146.1

Gene Ontology
Bibliography

Related articles in PubMed

RNase H2 catalytic core Aicardi-Gouti?res syndrome-related mutant invokes cGAS-STING innate immune-sensing pathway in mice.
Pokatayev V, Hasin N, Chon H, Cerritelli SM, Sakhuja K, Ward JM, Morris HD, Yan N, Crouch RJ
The Journal of experimental medicine213(3)329-36(2016 Mar)

Aicardi-Gouti?res syndrome: clues from the RNase H2 knock-out mouse.
Rabe B
Journal of molecular medicine (Berlin, Germany)91(11)1235-40(2013 Nov)

Ribonucleotides misincorporated into DNA act as strand-discrimination signals in eukaryotic mismatch repair.
Ghodgaonkar MM, Lazzaro F, Olivera-Pimentel M, Artola-Bor?n M, Cejka P, Reijns MA, Jackson AP, Plevani P, Muzi-Falconi M, Jiricny J
Molecular cell50(3)323-32(2013 May)

Enzymatic removal of ribonucleotides from DNA is essential for mammalian genome integrity and development.
Reijns MA, Rabe B, Rigby RE, Mill P, Astell KR, Lettice LA, Boyle S, Leitch A, Keighren M, Kilanowski F, Devenney PS, Sexton D, Grimes G, Holt IJ, Hill RE, Taylor MS, Lawson KA, Dorin JR, Jackson AP
Cell149(5)1008-22(2012 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

the G37S mutation of RNaseH2 led to increased expression of interferon-stimulated genes dependent on the cGAS-STING signaling pathway.
Title: RNase H2 catalytic core Aicardi-Gouti?res syndrome-related mutant invokes cGAS-STING innate immune-sensing pathway in mice.

Recent evidence gathered from ribonuclease H2 knock-out mice provides insight into the molecular mechanisms underlying Aicardi-Goutieres syndrome development and a potential role of DNA damage as a trigger of autoimmunity is discussed. [review]
Title: Aicardi-Gouti?res syndrome: clues from the RNase H2 knock-out mouse.

analysis of the RNase H2A subunit mutations that cause Aicardi-Goutieres syndrome
Title: Functional consequences of the RNase H2A subunit mutations that cause Aicardi-Goutieres syndrome.

Data show that the interwoven architecture of RNase H2B and RNase H2C that interface with RNase H2A in a complex ideally suited for nucleic acid binding and hydrolysis coupled to protein-protein interaction motifs.
Title: The structure of the mammalian RNase H2 complex provides insight into RNA.NA hybrid processing to prevent immune dysfunction.

The following Rnaseh2a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Rnaseh2a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu03825	NM_027187.4 Latest version!	Mus musculus ribonuclease H2, large subunit (Rnaseh2a), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OMu84351	NM_001364370.1 Latest version!	Mus musculus ribonuclease H2, large subunit (Rnaseh2a), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OMu03825	XM_011248497.3 Latest version!	Mus musculus ribonuclease H2, large subunit (Rnaseh2a), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OMu03825	XM_011248498.3 Latest version!	Mus musculus ribonuclease H2, large subunit (Rnaseh2a), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
View Old Accession Versions >>
OMu03825	XM_011248498.2	Mus musculus ribonuclease H2, large subunit (Rnaseh2a), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OMu03825	NM_027187.3	Mus musculus ribonuclease H2, large subunit (Rnaseh2a), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OMu03825	XM_011248497.2	Mus musculus ribonuclease H2, large subunit (Rnaseh2a), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Rnaseh2a ( NM_027187.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_081463.1 Mus musculus ribonuclease H2, large subunit (Rnaseh2a), transcript variant 1, mRNA.

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CloneID	OMu03825
Clone ID Related Accession (Same CDS sequence)	XM_011248498.3 , NM_027187.4 , XM_011248498.2 , XM_011248497.2 , NM_027187.3 , XM_011248497.3
Accession Version	NM_027187.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 906bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Mus musculus(house mouse)
Product	ribonuclease H2 subunit A isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY098728.1 and AK146518.1. On Jun 15, 2018 this sequence version replaced NM_027187.3. ##Evidence-Data-START## Transcript exon combination :: AK146518.1, BC038158.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGATCTCA GCGAGCTGGA GAGGGACAAT ACGGGTCGTT GTCGTCTGAG TTCTCCTGTA 
CCTGCTGTGT GTCTCAAGGA GCCGTGCGTT CTGGGCGTGG ATGAAGCGGG CCGAGGCCCT 
GTGCTTGGTC CCATGGTCTA CGCCATCTGT TACTGCCCCC TGTCTCGCTT GGCAGATCTG 
GAGGCCCTGA AAGTGGCAGA CTCTAAGACC TTGACAGAGA ACGAGCGGGA GAGGCTCTTT 
GCGAAAATGG AGGAGGATGG AGACTTTGTG GGTTGGGCTT TGGACGTCCT GTCTCCAAAC 
CTGATCTCTA CCAGCATGCT TGGGCGAGTC AAGTACAACC TCAACTCCCT GTCACACGAT 
ACAGCTGCGG GGCTGATACA GTACGCACTG GACCAGAATG TGAATGTCAC TCAGGTATTT 
GTGGACACTG TAGGAATGCC AGAGACATAC CAGGCTCGAT TACAACAGCA CTTTCCCGGG 
ATAGAGGTGA CAGTCAAGGC CAAAGCTGAC TCCCTGTTCC CTGTGGTCAG TGCTGCCAGC 
ATCTTTGCCA AGGTGGCCCG AGACAAGGCT GTGAAGAACT GGCAGTTTGT GGAAAATTTA 
CAGGATCTGG ACTCCGATTA TGGCTCAGGC TATCCCAATG ATCCCAAGAC CAAAGCCTGG 
CTGAGGAAAC ATGTGGACCC TGTGTTTGGC TTTCCCCAGT TTGTACGGTT CAGTTGGAGC 
ACAGCCCAGG CCATCCTGGA GAAGGAGGCA GAAGATGTCA TTTGGGAGGA CTCAGAAGCT 
GAGGAGGATC CTGAAAGACC GGGAAAAATC ACCTCCTACT TCAGCCAGGG CCCGCAGACC 
TGCCGCCCTC AGGCCCCCCA CAGATACTTC CAGGAGCGAG GCCTGGAGGC AGCCAGCAGC 
CTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_081463.1
CDS	91..996
Translation	MDLSELERDNTGRCRLSSPVPAVCLKEPCVLGVDEAGRGPVLGPMVYAICYCPLSRLADLEALKVADSKTLTENERERLFAKMEEDGDFVGWALDVLSPNLISTSMLGRVKYNLNSLSHDTAAGLIQYALDQNVNVTQVFVDTVGMPETYQARLQQHFPGIEVTVKAKADSLFPVVSAASIFAKVARDKAVKNWQFVENLQDLDSDYGSGYPNDPKTKAWLRKHVDPVFGFPQFVRFSWSTAQAILEKEAEDVIWEDSEAEEDPERPGKITSYFSQGPQTCRPQAPHRYFQERGLEAASSL

Target ORF information:

RefSeq Version	NM_027187.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus ribonuclease H2, large subunit (Rnaseh2a), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_027187.4

ORF Insert Sequence:

ATGGATCTCA GCGAGCTGGA GAGGGACAAT ACGGGTCGTT GTCGTCTGAG TTCTCCTGTA 
CCTGCTGTGT GTCTCAAGGA GCCGTGCGTT CTGGGCGTGG ATGAAGCGGG CCGAGGCCCT 
GTGCTTGGTC CCATGGTCTA CGCCATCTGT TACTGCCCCC TGTCTCGCTT GGCAGATCTG 
GAGGCCCTGA AAGTGGCAGA CTCTAAGACC TTGACAGAGA ACGAGCGGGA GAGGCTCTTT 
GCGAAAATGG AGGAGGATGG AGACTTTGTG GGTTGGGCTT TGGACGTCCT GTCTCCAAAC 
CTGATCTCTA CCAGCATGCT TGGGCGAGTC AAGTACAACC TCAACTCCCT GTCACACGAT 
ACAGCTGCGG GGCTGATACA GTACGCACTG GACCAGAATG TGAATGTCAC TCAGGTATTT 
GTGGACACTG TAGGAATGCC AGAGACATAC CAGGCTCGAT TACAACAGCA CTTTCCCGGG 
ATAGAGGTGA CAGTCAAGGC CAAAGCTGAC TCCCTGTTCC CTGTGGTCAG TGCTGCCAGC 
ATCTTTGCCA AGGTGGCCCG AGACAAGGCT GTGAAGAACT GGCAGTTTGT GGAAAATTTA 
CAGGATCTGG ACTCCGATTA TGGCTCAGGC TATCCCAATG ATCCCAAGAC CAAAGCCTGG 
CTGAGGAAAC ATGTGGACCC TGTGTTTGGC TTTCCCCAGT TTGTACGGTT CAGTTGGAGC 
ACAGCCCAGG CCATCCTGGA GAAGGAGGCA GAAGATGTCA TTTGGGAGGA CTCAGAAGCT 
GAGGAGGATC CTGAAAGACC GGGAAAAATC ACCTCCTACT TCAGCCAGGG CCCGCAGACC 
TGCCGCCCTC AGGCCCCCCA CAGATACTTC CAGGAGCGAG GCCTGGAGGC AGCCAGCAGC 
CTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Rnaseh2a ( NM_027187.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_081463.1 Mus musculus ribonuclease H2, large subunit (Rnaseh2a), mRNA.

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CloneID	OMu03825
Clone ID Related Accession (Same CDS sequence)	XM_011248498.3 , NM_027187.4 , XM_011248498.2 , XM_011248497.2 , NM_027187.3 , XM_011248497.3
Accession Version	NM_027187.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 906bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-29
Organism	Mus musculus(house mouse)
Product	ribonuclease H2 subunit A
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AK146518.1. On Apr 6, 2007 this sequence version replaced NM_027187.2. ##Evidence-Data-START## Transcript exon combination :: AK146518.1, BC038158.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END##

ATGGATCTCA GCGAGCTGGA GAGGGACAAT ACGGGTCGTT GTCGTCTGAG TTCTCCTGTA 
CCTGCTGTGT GTCTCAAGGA GCCGTGCGTT CTGGGCGTGG ATGAAGCGGG CCGAGGCCCT 
GTGCTTGGTC CCATGGTCTA CGCCATCTGT TACTGCCCCC TGTCTCGCTT GGCAGATCTG 
GAGGCCCTGA AAGTGGCAGA CTCTAAGACC TTGACAGAGA ACGAGCGGGA GAGGCTCTTT 
GCGAAAATGG AGGAGGATGG AGACTTTGTG GGTTGGGCTT TGGACGTCCT GTCTCCAAAC 
CTGATCTCTA CCAGCATGCT TGGGCGAGTC AAGTACAACC TCAACTCCCT GTCACACGAT 
ACAGCTGCGG GGCTGATACA GTACGCACTG GACCAGAATG TGAATGTCAC TCAGGTATTT 
GTGGACACTG TAGGAATGCC AGAGACATAC CAGGCTCGAT TACAACAGCA CTTTCCCGGG 
ATAGAGGTGA CAGTCAAGGC CAAAGCTGAC TCCCTGTTCC CTGTGGTCAG TGCTGCCAGC 
ATCTTTGCCA AGGTGGCCCG AGACAAGGCT GTGAAGAACT GGCAGTTTGT GGAAAATTTA 
CAGGATCTGG ACTCCGATTA TGGCTCAGGC TATCCCAATG ATCCCAAGAC CAAAGCCTGG 
CTGAGGAAAC ATGTGGACCC TGTGTTTGGC TTTCCCCAGT TTGTACGGTT CAGTTGGAGC 
ACAGCCCAGG CCATCCTGGA GAAGGAGGCA GAAGATGTCA TTTGGGAGGA CTCAGAAGCT 
GAGGAGGATC CTGAAAGACC GGGAAAAATC ACCTCCTACT TCAGCCAGGG CCCGCAGACC 
TGCCGCCCTC AGGCCCCCCA CAGATACTTC CAGGAGCGAG GCCTGGAGGC AGCCAGCAGC 
CTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_081463.1
CDS	26..931
Translation	MDLSELERDNTGRCRLSSPVPAVCLKEPCVLGVDEAGRGPVLGPMVYAICYCPLSRLADLEALKVADSKTLTENERERLFAKMEEDGDFVGWALDVLSPNLISTSMLGRVKYNLNSLSHDTAAGLIQYALDQNVNVTQVFVDTVGMPETYQARLQQHFPGIEVTVKAKADSLFPVVSAASIFAKVARDKAVKNWQFVENLQDLDSDYGSGYPNDPKTKAWLRKHVDPVFGFPQFVRFSWSTAQAILEKEAEDVIWEDSEAEEDPERPGKITSYFSQGPQTCRPQAPHRYFQERGLEAASSL

Target ORF information:

RefSeq Version	NM_027187.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus ribonuclease H2, large subunit (Rnaseh2a), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_027187.3

ORF Insert Sequence:

ATGGATCTCA GCGAGCTGGA GAGGGACAAT ACGGGTCGTT GTCGTCTGAG TTCTCCTGTA 
CCTGCTGTGT GTCTCAAGGA GCCGTGCGTT CTGGGCGTGG ATGAAGCGGG CCGAGGCCCT 
GTGCTTGGTC CCATGGTCTA CGCCATCTGT TACTGCCCCC TGTCTCGCTT GGCAGATCTG 
GAGGCCCTGA AAGTGGCAGA CTCTAAGACC TTGACAGAGA ACGAGCGGGA GAGGCTCTTT 
GCGAAAATGG AGGAGGATGG AGACTTTGTG GGTTGGGCTT TGGACGTCCT GTCTCCAAAC 
CTGATCTCTA CCAGCATGCT TGGGCGAGTC AAGTACAACC TCAACTCCCT GTCACACGAT 
ACAGCTGCGG GGCTGATACA GTACGCACTG GACCAGAATG TGAATGTCAC TCAGGTATTT 
GTGGACACTG TAGGAATGCC AGAGACATAC CAGGCTCGAT TACAACAGCA CTTTCCCGGG 
ATAGAGGTGA CAGTCAAGGC CAAAGCTGAC TCCCTGTTCC CTGTGGTCAG TGCTGCCAGC 
ATCTTTGCCA AGGTGGCCCG AGACAAGGCT GTGAAGAACT GGCAGTTTGT GGAAAATTTA 
CAGGATCTGG ACTCCGATTA TGGCTCAGGC TATCCCAATG ATCCCAAGAC CAAAGCCTGG 
CTGAGGAAAC ATGTGGACCC TGTGTTTGGC TTTCCCCAGT TTGTACGGTT CAGTTGGAGC 
ACAGCCCAGG CCATCCTGGA GAAGGAGGCA GAAGATGTCA TTTGGGAGGA CTCAGAAGCT 
GAGGAGGATC CTGAAAGACC GGGAAAAATC ACCTCCTACT TCAGCCAGGG CCCGCAGACC 
TGCCGCCCTC AGGCCCCCCA CAGATACTTC CAGGAGCGAG GCCTGGAGGC AGCCAGCAGC 
CTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Rnaseh2a ( XM_011248498.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011246800.1 Mus musculus ribonuclease H2, large subunit (Rnaseh2a), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu03825
Clone ID Related Accession (Same CDS sequence)	XM_011248498.3 , NM_027187.4 , XM_011248498.2 , XM_011248497.2 , NM_027187.3 , XM_011248497.3
Accession Version	XM_011248498.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 906bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	ribonuclease H2 subunit A isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000074.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_011248498.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGATCTCA GCGAGCTGGA GAGGGACAAT ACGGGTCGTT GTCGTCTGAG TTCTCCTGTA 
CCTGCTGTGT GTCTCAAGGA GCCGTGCGTT CTGGGCGTGG ATGAAGCGGG CCGAGGCCCT 
GTGCTTGGTC CCATGGTCTA CGCCATCTGT TACTGCCCCC TGTCTCGCTT GGCAGATCTG 
GAGGCCCTGA AAGTGGCAGA CTCTAAGACC TTGACAGAGA ACGAGCGGGA GAGGCTCTTT 
GCGAAAATGG AGGAGGATGG AGACTTTGTG GGTTGGGCTT TGGACGTCCT GTCTCCAAAC 
CTGATCTCTA CCAGCATGCT TGGGCGAGTC AAGTACAACC TCAACTCCCT GTCACACGAT 
ACAGCTGCGG GGCTGATACA GTACGCACTG GACCAGAATG TGAATGTCAC TCAGGTATTT 
GTGGACACTG TAGGAATGCC AGAGACATAC CAGGCTCGAT TACAACAGCA CTTTCCCGGG 
ATAGAGGTGA CAGTCAAGGC CAAAGCTGAC TCCCTGTTCC CTGTGGTCAG TGCTGCCAGC 
ATCTTTGCCA AGGTGGCCCG AGACAAGGCT GTGAAGAACT GGCAGTTTGT GGAAAATTTA 
CAGGATCTGG ACTCCGATTA TGGCTCAGGC TATCCCAATG ATCCCAAGAC CAAAGCCTGG 
CTGAGGAAAC ATGTGGACCC TGTGTTTGGC TTTCCCCAGT TTGTACGGTT CAGTTGGAGC 
ACAGCCCAGG CCATCCTGGA GAAGGAGGCA GAAGATGTCA TTTGGGAGGA CTCAGAAGCT 
GAGGAGGATC CTGAAAGACC GGGAAAAATC ACCTCCTACT TCAGCCAGGG CCCGCAGACC 
TGCCGCCCTC AGGCCCCCCA CAGATACTTC CAGGAGCGAG GCCTGGAGGC AGCCAGCAGC 
CTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011246800.1
CDS	697..1602
Translation	MDLSELERDNTGRCRLSSPVPAVCLKEPCVLGVDEAGRGPVLGPMVYAICYCPLSRLADLEALKVADSKTLTENERERLFAKMEEDGDFVGWALDVLSPNLISTSMLGRVKYNLNSLSHDTAAGLIQYALDQNVNVTQVFVDTVGMPETYQARLQQHFPGIEVTVKAKADSLFPVVSAASIFAKVARDKAVKNWQFVENLQDLDSDYGSGYPNDPKTKAWLRKHVDPVFGFPQFVRFSWSTAQAILEKEAEDVIWEDSEAEEDPERPGKITSYFSQGPQTCRPQAPHRYFQERGLEAASSL

Target ORF information:

RefSeq Version	XM_011248498.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus ribonuclease H2, large subunit (Rnaseh2a), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011248498.2

ORF Insert Sequence:

ATGGATCTCA GCGAGCTGGA GAGGGACAAT ACGGGTCGTT GTCGTCTGAG TTCTCCTGTA 
CCTGCTGTGT GTCTCAAGGA GCCGTGCGTT CTGGGCGTGG ATGAAGCGGG CCGAGGCCCT 
GTGCTTGGTC CCATGGTCTA CGCCATCTGT TACTGCCCCC TGTCTCGCTT GGCAGATCTG 
GAGGCCCTGA AAGTGGCAGA CTCTAAGACC TTGACAGAGA ACGAGCGGGA GAGGCTCTTT 
GCGAAAATGG AGGAGGATGG AGACTTTGTG GGTTGGGCTT TGGACGTCCT GTCTCCAAAC 
CTGATCTCTA CCAGCATGCT TGGGCGAGTC AAGTACAACC TCAACTCCCT GTCACACGAT 
ACAGCTGCGG GGCTGATACA GTACGCACTG GACCAGAATG TGAATGTCAC TCAGGTATTT 
GTGGACACTG TAGGAATGCC AGAGACATAC CAGGCTCGAT TACAACAGCA CTTTCCCGGG 
ATAGAGGTGA CAGTCAAGGC CAAAGCTGAC TCCCTGTTCC CTGTGGTCAG TGCTGCCAGC 
ATCTTTGCCA AGGTGGCCCG AGACAAGGCT GTGAAGAACT GGCAGTTTGT GGAAAATTTA 
CAGGATCTGG ACTCCGATTA TGGCTCAGGC TATCCCAATG ATCCCAAGAC CAAAGCCTGG 
CTGAGGAAAC ATGTGGACCC TGTGTTTGGC TTTCCCCAGT TTGTACGGTT CAGTTGGAGC 
ACAGCCCAGG CCATCCTGGA GAAGGAGGCA GAAGATGTCA TTTGGGAGGA CTCAGAAGCT 
GAGGAGGATC CTGAAAGACC GGGAAAAATC ACCTCCTACT TCAGCCAGGG CCCGCAGACC 
TGCCGCCCTC AGGCCCCCCA CAGATACTTC CAGGAGCGAG GCCTGGAGGC AGCCAGCAGC 
CTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Rnaseh2a ( XM_011248497.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011246799.1 Mus musculus ribonuclease H2, large subunit (Rnaseh2a), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu03825
Clone ID Related Accession (Same CDS sequence)	XM_011248498.3 , NM_027187.4 , XM_011248498.2 , XM_011248497.2 , NM_027187.3 , XM_011248497.3
Accession Version	XM_011248497.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 906bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	ribonuclease H2 subunit A isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000074.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_011248497.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGATCTCA GCGAGCTGGA GAGGGACAAT ACGGGTCGTT GTCGTCTGAG TTCTCCTGTA 
CCTGCTGTGT GTCTCAAGGA GCCGTGCGTT CTGGGCGTGG ATGAAGCGGG CCGAGGCCCT 
GTGCTTGGTC CCATGGTCTA CGCCATCTGT TACTGCCCCC TGTCTCGCTT GGCAGATCTG 
GAGGCCCTGA AAGTGGCAGA CTCTAAGACC TTGACAGAGA ACGAGCGGGA GAGGCTCTTT 
GCGAAAATGG AGGAGGATGG AGACTTTGTG GGTTGGGCTT TGGACGTCCT GTCTCCAAAC 
CTGATCTCTA CCAGCATGCT TGGGCGAGTC AAGTACAACC TCAACTCCCT GTCACACGAT 
ACAGCTGCGG GGCTGATACA GTACGCACTG GACCAGAATG TGAATGTCAC TCAGGTATTT 
GTGGACACTG TAGGAATGCC AGAGACATAC CAGGCTCGAT TACAACAGCA CTTTCCCGGG 
ATAGAGGTGA CAGTCAAGGC CAAAGCTGAC TCCCTGTTCC CTGTGGTCAG TGCTGCCAGC 
ATCTTTGCCA AGGTGGCCCG AGACAAGGCT GTGAAGAACT GGCAGTTTGT GGAAAATTTA 
CAGGATCTGG ACTCCGATTA TGGCTCAGGC TATCCCAATG ATCCCAAGAC CAAAGCCTGG 
CTGAGGAAAC ATGTGGACCC TGTGTTTGGC TTTCCCCAGT TTGTACGGTT CAGTTGGAGC 
ACAGCCCAGG CCATCCTGGA GAAGGAGGCA GAAGATGTCA TTTGGGAGGA CTCAGAAGCT 
GAGGAGGATC CTGAAAGACC GGGAAAAATC ACCTCCTACT TCAGCCAGGG CCCGCAGACC 
TGCCGCCCTC AGGCCCCCCA CAGATACTTC CAGGAGCGAG GCCTGGAGGC AGCCAGCAGC 
CTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011246799.1
CDS	598..1503
Translation	MDLSELERDNTGRCRLSSPVPAVCLKEPCVLGVDEAGRGPVLGPMVYAICYCPLSRLADLEALKVADSKTLTENERERLFAKMEEDGDFVGWALDVLSPNLISTSMLGRVKYNLNSLSHDTAAGLIQYALDQNVNVTQVFVDTVGMPETYQARLQQHFPGIEVTVKAKADSLFPVVSAASIFAKVARDKAVKNWQFVENLQDLDSDYGSGYPNDPKTKAWLRKHVDPVFGFPQFVRFSWSTAQAILEKEAEDVIWEDSEAEEDPERPGKITSYFSQGPQTCRPQAPHRYFQERGLEAASSL

Target ORF information:

RefSeq Version	XM_011248497.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus ribonuclease H2, large subunit (Rnaseh2a), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011248497.2

ORF Insert Sequence:

ATGGATCTCA GCGAGCTGGA GAGGGACAAT ACGGGTCGTT GTCGTCTGAG TTCTCCTGTA 
CCTGCTGTGT GTCTCAAGGA GCCGTGCGTT CTGGGCGTGG ATGAAGCGGG CCGAGGCCCT 
GTGCTTGGTC CCATGGTCTA CGCCATCTGT TACTGCCCCC TGTCTCGCTT GGCAGATCTG 
GAGGCCCTGA AAGTGGCAGA CTCTAAGACC TTGACAGAGA ACGAGCGGGA GAGGCTCTTT 
GCGAAAATGG AGGAGGATGG AGACTTTGTG GGTTGGGCTT TGGACGTCCT GTCTCCAAAC 
CTGATCTCTA CCAGCATGCT TGGGCGAGTC AAGTACAACC TCAACTCCCT GTCACACGAT 
ACAGCTGCGG GGCTGATACA GTACGCACTG GACCAGAATG TGAATGTCAC TCAGGTATTT 
GTGGACACTG TAGGAATGCC AGAGACATAC CAGGCTCGAT TACAACAGCA CTTTCCCGGG 
ATAGAGGTGA CAGTCAAGGC CAAAGCTGAC TCCCTGTTCC CTGTGGTCAG TGCTGCCAGC 
ATCTTTGCCA AGGTGGCCCG AGACAAGGCT GTGAAGAACT GGCAGTTTGT GGAAAATTTA 
CAGGATCTGG ACTCCGATTA TGGCTCAGGC TATCCCAATG ATCCCAAGAC CAAAGCCTGG 
CTGAGGAAAC ATGTGGACCC TGTGTTTGGC TTTCCCCAGT TTGTACGGTT CAGTTGGAGC 
ACAGCCCAGG CCATCCTGGA GAAGGAGGCA GAAGATGTCA TTTGGGAGGA CTCAGAAGCT 
GAGGAGGATC CTGAAAGACC GGGAAAAATC ACCTCCTACT TCAGCCAGGG CCCGCAGACC 
TGCCGCCCTC AGGCCCCCCA CAGATACTTC CAGGAGCGAG GCCTGGAGGC AGCCAGCAGC 
CTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Rnaseh2a ( NM_001364370.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001351299.1 Mus musculus ribonuclease H2, large subunit (Rnaseh2a), transcript variant 2, mRNA.

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CloneID	OMu84351
Clone ID Related Accession (Same CDS sequence)	NM_001364370.1
Accession Version	NM_001364370.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 765bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-29
Organism	Mus musculus(house mouse)
Product	ribonuclease H2 subunit A isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC163703.4. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: BC029252.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGATCTCA GCGAGCTGGA GAGGGACAAT ACGGGTCGTT GTCGTCTGAG TTCTCCTGTA 
CCTGCTGTGT GTCTCAAGGA GCCGTGCGTT CTGGGCGTGG ATGAAGCGGG CCGAGGCCCT 
GTGCTTGGTC CCATGGTCTA CGCCATCTGT TACTGCCCCC TGTCTCGCTT GGCAGATCTG 
GAGGCCCTGA AAGTGGCAGA CTCTAAGACC TTGACAGAGA ACGAGCGGGA GAGGCTCTTT 
GCGAAAATGG AGGAGGATGG AGACTTTGTG GGTTGGGCTT TGGACGTCCT GTCTCCAAAC 
CTGATCTCTA CCAGCATGCT TGGGCGAGTC AAGTACAACC TCAACTCCCT GTCACACGAT 
ACAGCTGCGG GGCTGATACA GTACGCACTG GACCAGAATG TGAATGTCAC TCAGGTATTT 
GTGGACACTG TAGGAATGCC AGAGACATAC CAGGCTCGAT TACAACAGCA CTTTCCCGGG 
ATAGAGGTGA CAGTCAAGGC CAAAGCTGAC TCCCTGTTCC CTGTGGTCAG TGCTGCCAGC 
ATCTTTGCCA AGGTGGCCCG AGACAAGGCT GTGAAGAACT GGCAGTTTGT GGAAAATTTA 
CAGGATCTGG ACTCCGATTA TGGCTCAGGC TATCCCAATG ATCCCAAGAC CAAAGCCTGG 
CTGAGGAAAC ATGTGGACCC TGTGTTTGGC TTTCCCCAGT TTGTACGGTT CAGTTGGAGC 
ACAGCCCAGG CCATCCTGGA GAAGGAGGCA GAAGATGTCA TTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001351299.1
CDS	91..855
Translation	MDLSELERDNTGRCRLSSPVPAVCLKEPCVLGVDEAGRGPVLGPMVYAICYCPLSRLADLEALKVADSKTLTENERERLFAKMEEDGDFVGWALDVLSPNLISTSMLGRVKYNLNSLSHDTAAGLIQYALDQNVNVTQVFVDTVGMPETYQARLQQHFPGIEVTVKAKADSLFPVVSAASIFAKVARDKAVKNWQFVENLQDLDSDYGSGYPNDPKTKAWLRKHVDPVFGFPQFVRFSWSTAQAILEKEAEDVI

Target ORF information:

RefSeq Version	NM_001364370.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus ribonuclease H2, large subunit (Rnaseh2a), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001364370.1

ORF Insert Sequence:

ATGGATCTCA GCGAGCTGGA GAGGGACAAT ACGGGTCGTT GTCGTCTGAG TTCTCCTGTA 
CCTGCTGTGT GTCTCAAGGA GCCGTGCGTT CTGGGCGTGG ATGAAGCGGG CCGAGGCCCT 
GTGCTTGGTC CCATGGTCTA CGCCATCTGT TACTGCCCCC TGTCTCGCTT GGCAGATCTG 
GAGGCCCTGA AAGTGGCAGA CTCTAAGACC TTGACAGAGA ACGAGCGGGA GAGGCTCTTT 
GCGAAAATGG AGGAGGATGG AGACTTTGTG GGTTGGGCTT TGGACGTCCT GTCTCCAAAC 
CTGATCTCTA CCAGCATGCT TGGGCGAGTC AAGTACAACC TCAACTCCCT GTCACACGAT 
ACAGCTGCGG GGCTGATACA GTACGCACTG GACCAGAATG TGAATGTCAC TCAGGTATTT 
GTGGACACTG TAGGAATGCC AGAGACATAC CAGGCTCGAT TACAACAGCA CTTTCCCGGG 
ATAGAGGTGA CAGTCAAGGC CAAAGCTGAC TCCCTGTTCC CTGTGGTCAG TGCTGCCAGC 
ATCTTTGCCA AGGTGGCCCG AGACAAGGCT GTGAAGAACT GGCAGTTTGT GGAAAATTTA 
CAGGATCTGG ACTCCGATTA TGGCTCAGGC TATCCCAATG ATCCCAAGAC CAAAGCCTGG 
CTGAGGAAAC ATGTGGACCC TGTGTTTGGC TTTCCCCAGT TTGTACGGTT CAGTTGGAGC 
ACAGCCCAGG CCATCCTGGA GAAGGAGGCA GAAGATGTCA TTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Rnaseh2a ( XM_011248498.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011246800.1 Mus musculus ribonuclease H2, large subunit (Rnaseh2a), transcript variant X2, mRNA.

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CloneID	OMu03825
Clone ID Related Accession (Same CDS sequence)	XM_011248498.3 , NM_027187.4 , XM_011248498.2 , XM_011248497.2 , NM_027187.3 , XM_011248497.3
Accession Version	XM_011248498.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 906bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	ribonuclease H2 subunit A isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000074.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_011248498.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGATCTCA GCGAGCTGGA GAGGGACAAT ACGGGTCGTT GTCGTCTGAG TTCTCCTGTA 
CCTGCTGTGT GTCTCAAGGA GCCGTGCGTT CTGGGCGTGG ATGAAGCGGG CCGAGGCCCT 
GTGCTTGGTC CCATGGTCTA CGCCATCTGT TACTGCCCCC TGTCTCGCTT GGCAGATCTG 
GAGGCCCTGA AAGTGGCAGA CTCTAAGACC TTGACAGAGA ACGAGCGGGA GAGGCTCTTT 
GCGAAAATGG AGGAGGATGG AGACTTTGTG GGTTGGGCTT TGGACGTCCT GTCTCCAAAC 
CTGATCTCTA CCAGCATGCT TGGGCGAGTC AAGTACAACC TCAACTCCCT GTCACACGAT 
ACAGCTGCGG GGCTGATACA GTACGCACTG GACCAGAATG TGAATGTCAC TCAGGTATTT 
GTGGACACTG TAGGAATGCC AGAGACATAC CAGGCTCGAT TACAACAGCA CTTTCCCGGG 
ATAGAGGTGA CAGTCAAGGC CAAAGCTGAC TCCCTGTTCC CTGTGGTCAG TGCTGCCAGC 
ATCTTTGCCA AGGTGGCCCG AGACAAGGCT GTGAAGAACT GGCAGTTTGT GGAAAATTTA 
CAGGATCTGG ACTCCGATTA TGGCTCAGGC TATCCCAATG ATCCCAAGAC CAAAGCCTGG 
CTGAGGAAAC ATGTGGACCC TGTGTTTGGC TTTCCCCAGT TTGTACGGTT CAGTTGGAGC 
ACAGCCCAGG CCATCCTGGA GAAGGAGGCA GAAGATGTCA TTTGGGAGGA CTCAGAAGCT 
GAGGAGGATC CTGAAAGACC GGGAAAAATC ACCTCCTACT TCAGCCAGGG CCCGCAGACC 
TGCCGCCCTC AGGCCCCCCA CAGATACTTC CAGGAGCGAG GCCTGGAGGC AGCCAGCAGC 
CTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011246800.1
CDS	1009..1914
Translation	MDLSELERDNTGRCRLSSPVPAVCLKEPCVLGVDEAGRGPVLGPMVYAICYCPLSRLADLEALKVADSKTLTENERERLFAKMEEDGDFVGWALDVLSPNLISTSMLGRVKYNLNSLSHDTAAGLIQYALDQNVNVTQVFVDTVGMPETYQARLQQHFPGIEVTVKAKADSLFPVVSAASIFAKVARDKAVKNWQFVENLQDLDSDYGSGYPNDPKTKAWLRKHVDPVFGFPQFVRFSWSTAQAILEKEAEDVIWEDSEAEEDPERPGKITSYFSQGPQTCRPQAPHRYFQERGLEAASSL

Target ORF information:

RefSeq Version	XM_011248498.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus ribonuclease H2, large subunit (Rnaseh2a), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011248498.3

ORF Insert Sequence:

ATGGATCTCA GCGAGCTGGA GAGGGACAAT ACGGGTCGTT GTCGTCTGAG TTCTCCTGTA 
CCTGCTGTGT GTCTCAAGGA GCCGTGCGTT CTGGGCGTGG ATGAAGCGGG CCGAGGCCCT 
GTGCTTGGTC CCATGGTCTA CGCCATCTGT TACTGCCCCC TGTCTCGCTT GGCAGATCTG 
GAGGCCCTGA AAGTGGCAGA CTCTAAGACC TTGACAGAGA ACGAGCGGGA GAGGCTCTTT 
GCGAAAATGG AGGAGGATGG AGACTTTGTG GGTTGGGCTT TGGACGTCCT GTCTCCAAAC 
CTGATCTCTA CCAGCATGCT TGGGCGAGTC AAGTACAACC TCAACTCCCT GTCACACGAT 
ACAGCTGCGG GGCTGATACA GTACGCACTG GACCAGAATG TGAATGTCAC TCAGGTATTT 
GTGGACACTG TAGGAATGCC AGAGACATAC CAGGCTCGAT TACAACAGCA CTTTCCCGGG 
ATAGAGGTGA CAGTCAAGGC CAAAGCTGAC TCCCTGTTCC CTGTGGTCAG TGCTGCCAGC 
ATCTTTGCCA AGGTGGCCCG AGACAAGGCT GTGAAGAACT GGCAGTTTGT GGAAAATTTA 
CAGGATCTGG ACTCCGATTA TGGCTCAGGC TATCCCAATG ATCCCAAGAC CAAAGCCTGG 
CTGAGGAAAC ATGTGGACCC TGTGTTTGGC TTTCCCCAGT TTGTACGGTT CAGTTGGAGC 
ACAGCCCAGG CCATCCTGGA GAAGGAGGCA GAAGATGTCA TTTGGGAGGA CTCAGAAGCT 
GAGGAGGATC CTGAAAGACC GGGAAAAATC ACCTCCTACT TCAGCCAGGG CCCGCAGACC 
TGCCGCCCTC AGGCCCCCCA CAGATACTTC CAGGAGCGAG GCCTGGAGGC AGCCAGCAGC 
CTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Rnaseh2a ( XM_011248497.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011246799.1 Mus musculus ribonuclease H2, large subunit (Rnaseh2a), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu03825
Clone ID Related Accession (Same CDS sequence)	XM_011248498.3 , NM_027187.4 , XM_011248498.2 , XM_011248497.2 , NM_027187.3 , XM_011248497.3
Accession Version	XM_011248497.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 906bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	ribonuclease H2 subunit A isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000074.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_011248497.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGATCTCA GCGAGCTGGA GAGGGACAAT ACGGGTCGTT GTCGTCTGAG TTCTCCTGTA 
CCTGCTGTGT GTCTCAAGGA GCCGTGCGTT CTGGGCGTGG ATGAAGCGGG CCGAGGCCCT 
GTGCTTGGTC CCATGGTCTA CGCCATCTGT TACTGCCCCC TGTCTCGCTT GGCAGATCTG 
GAGGCCCTGA AAGTGGCAGA CTCTAAGACC TTGACAGAGA ACGAGCGGGA GAGGCTCTTT 
GCGAAAATGG AGGAGGATGG AGACTTTGTG GGTTGGGCTT TGGACGTCCT GTCTCCAAAC 
CTGATCTCTA CCAGCATGCT TGGGCGAGTC AAGTACAACC TCAACTCCCT GTCACACGAT 
ACAGCTGCGG GGCTGATACA GTACGCACTG GACCAGAATG TGAATGTCAC TCAGGTATTT 
GTGGACACTG TAGGAATGCC AGAGACATAC CAGGCTCGAT TACAACAGCA CTTTCCCGGG 
ATAGAGGTGA CAGTCAAGGC CAAAGCTGAC TCCCTGTTCC CTGTGGTCAG TGCTGCCAGC 
ATCTTTGCCA AGGTGGCCCG AGACAAGGCT GTGAAGAACT GGCAGTTTGT GGAAAATTTA 
CAGGATCTGG ACTCCGATTA TGGCTCAGGC TATCCCAATG ATCCCAAGAC CAAAGCCTGG 
CTGAGGAAAC ATGTGGACCC TGTGTTTGGC TTTCCCCAGT TTGTACGGTT CAGTTGGAGC 
ACAGCCCAGG CCATCCTGGA GAAGGAGGCA GAAGATGTCA TTTGGGAGGA CTCAGAAGCT 
GAGGAGGATC CTGAAAGACC GGGAAAAATC ACCTCCTACT TCAGCCAGGG CCCGCAGACC 
TGCCGCCCTC AGGCCCCCCA CAGATACTTC CAGGAGCGAG GCCTGGAGGC AGCCAGCAGC 
CTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011246799.1
CDS	821..1726
Translation	MDLSELERDNTGRCRLSSPVPAVCLKEPCVLGVDEAGRGPVLGPMVYAICYCPLSRLADLEALKVADSKTLTENERERLFAKMEEDGDFVGWALDVLSPNLISTSMLGRVKYNLNSLSHDTAAGLIQYALDQNVNVTQVFVDTVGMPETYQARLQQHFPGIEVTVKAKADSLFPVVSAASIFAKVARDKAVKNWQFVENLQDLDSDYGSGYPNDPKTKAWLRKHVDPVFGFPQFVRFSWSTAQAILEKEAEDVIWEDSEAEEDPERPGKITSYFSQGPQTCRPQAPHRYFQERGLEAASSL

Target ORF information:

RefSeq Version	XM_011248497.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus ribonuclease H2, large subunit (Rnaseh2a), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011248497.3

ORF Insert Sequence:

ATGGATCTCA GCGAGCTGGA GAGGGACAAT ACGGGTCGTT GTCGTCTGAG TTCTCCTGTA 
CCTGCTGTGT GTCTCAAGGA GCCGTGCGTT CTGGGCGTGG ATGAAGCGGG CCGAGGCCCT 
GTGCTTGGTC CCATGGTCTA CGCCATCTGT TACTGCCCCC TGTCTCGCTT GGCAGATCTG 
GAGGCCCTGA AAGTGGCAGA CTCTAAGACC TTGACAGAGA ACGAGCGGGA GAGGCTCTTT 
GCGAAAATGG AGGAGGATGG AGACTTTGTG GGTTGGGCTT TGGACGTCCT GTCTCCAAAC 
CTGATCTCTA CCAGCATGCT TGGGCGAGTC AAGTACAACC TCAACTCCCT GTCACACGAT 
ACAGCTGCGG GGCTGATACA GTACGCACTG GACCAGAATG TGAATGTCAC TCAGGTATTT 
GTGGACACTG TAGGAATGCC AGAGACATAC CAGGCTCGAT TACAACAGCA CTTTCCCGGG 
ATAGAGGTGA CAGTCAAGGC CAAAGCTGAC TCCCTGTTCC CTGTGGTCAG TGCTGCCAGC 
ATCTTTGCCA AGGTGGCCCG AGACAAGGCT GTGAAGAACT GGCAGTTTGT GGAAAATTTA 
CAGGATCTGG ACTCCGATTA TGGCTCAGGC TATCCCAATG ATCCCAAGAC CAAAGCCTGG 
CTGAGGAAAC ATGTGGACCC TGTGTTTGGC TTTCCCCAGT TTGTACGGTT CAGTTGGAGC 
ACAGCCCAGG CCATCCTGGA GAAGGAGGCA GAAGATGTCA TTTGGGAGGA CTCAGAAGCT 
GAGGAGGATC CTGAAAGACC GGGAAAAATC ACCTCCTACT TCAGCCAGGG CCCGCAGACC 
TGCCGCCCTC AGGCCCCCCA CAGATACTTC CAGGAGCGAG GCCTGGAGGC AGCCAGCAGC 
CTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

RNase H2 catalytic core Aicardi-Gouti?res syndrome-related mutant invokes cGAS-STING innate immune-sensing pathway in mice.
The Journal of experimental medicine213(3)329-36(2016 Mar)
Pokatayev V,Hasin N,Chon H,Cerritelli SM,Sakhuja K,Ward JM,Morris HD,Yan N,Crouch RJ

Aicardi-Gouti?res syndrome: clues from the RNase H2 knock-out mouse.
Journal of molecular medicine (Berlin, Germany)91(11)1235-40(2013 Nov)
Rabe B

Ribonucleotides misincorporated into DNA act as strand-discrimination signals in eukaryotic mismatch repair.
Molecular cell50(3)323-32(2013 May)
Ghodgaonkar MM,Lazzaro F,Olivera-Pimentel M,Artola-Bor?n M,Cejka P,Reijns MA,Jackson AP,Plevani P,Muzi-Falconi M,Jiricny J

Enzymatic removal of ribonucleotides from DNA is essential for mammalian genome integrity and development.
Cell149(5)1008-22(2012 May)
Reijns MA,Rabe B,Rigby RE,Mill P,Astell KR,Lettice LA,Boyle S,Leitch A,Keighren M,Kilanowski F,Devenney PS,Sexton D,Grimes G,Holt IJ,Hill RE,Taylor MS,Lawson KA,Dorin JR,Jackson AP

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Rnaseh2a cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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