Dhrs7c cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Dhrs7c
Entrez Gene ID	68460
Full Name	dehydrogenase/reductase (SDR family) member 7C
Synonyms	1110001P11Rik,AI120487,SRP-35
General protein information	Preferred Names dehydrogenase/reductase (SDR family) member 7C Names dehydrogenase/reductase SDR family member 7C short-chain dehydrogenase/reductase family 32C member 2
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 11 Map Location: 11\|11 B3

mRNA and Protein(s)

mRNA	Protein	Name
NM_001013013.2	NP_001013031.2	dehydrogenase/reductase SDR family member 7C precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	DHRS7C	NP_001099041.1
Xenopus tropicalis (tropical clawed frog)	dhrs7c	NP_001107423.1
	LOC722045	XP_001118243.2
Canis lupus familiaris (dog)	DHRS7C	XP_536640.2
Mus musculus (house mouse)	Dhrs7c	NP_001013031.2
Gallus gallus (chicken)	DHRS7C	NP_001264924.1
Danio rerio (zebrafish)	dhrs7cb	NP_001018493.1
Rattus norvegicus (Norway rat)	Dhrs7c	NP_001258527.1
Pan troglodytes (chimpanzee)	DHRS7C	XP_511842.4
Bos taurus (cattle)	DHRS7C	NP_001069013.1

Gene Ontology
Bibliography

Related articles in PubMed

Over-expression of a retinol dehydrogenase (SRP35/DHRS7C) in skeletal muscle activates mTORC2, enhances glucose metabolism and muscle performance.
Ruiz A, Dror E, Handschin C, Furrer R, Perez-Schindler J, Bachmann C, Treves S, Zorzato F
Scientific reports8(1)636(2018 Jan)

Functional loss of DHRS7C induces intracellular Ca2+ overload and myotube enlargement in C2C12 cells via calpain activation.
Arai S, Ikeda M, Ide T, Matsuo Y, Fujino T, Hirano K, Sunagawa K, Tsutsui H
American journal of physiology. Cell physiology312(1)C29-C39(2017 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Taken together, our findings suggested that DHRS7C maintains intracellular Ca(2+) homeostasis involving the ER/SR and that functional loss of DHRS7C leads to Ca(2+) overload in the cytosol and ER/SR, resulting in enlarged cellular morphology via calpain activation
Title: Functional loss of DHRS7C induces intracellular Ca2+ overload and myotube enlargement in C2C12 cells via calpain activation.

skeletal muscle SRP-35 is involved in the generation of all-trans-retinaldehyde and may play an important role in the generation of intracellular signals linking Ca2+ release (i.e. muscle activity) to metabolism.
Title: SRP-35, a newly identified protein of the skeletal muscle sarcoplasmic reticulum, is a retinol dehydrogenase.

The following Dhrs7c gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Dhrs7c cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu18084	NM_001013013.2 Latest version!	Mus musculus dehydrogenase/reductase (SDR family) member 7C (Dhrs7c), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Dhrs7c ( NM_001013013.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001013031.2 Mus musculus dehydrogenase/reductase (SDR family) member 7C (Dhrs7c), mRNA.

Price & Availability↑

CloneID	OMu18084
Clone ID Related Accession (Same CDS sequence)	NM_001013013.2
Accession Version	NM_001013013.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 936bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Mus musculus(house mouse)
Product	dehydrogenase/reductase SDR family member 7C precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from W53606.1, AA063835.1, CJ048402.1, AI391290.1 and AI414355.1. On Sep 28, 2007 this sequence version replaced NM_001013013.1. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849383 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGGCTCA TGGCTGTCCT GATGCTACCC CTGCTGCTGC TGGGAATCAG CGGCCTCCTC 
TTCATTTACC AGGAGGCATC CAGGCTGTGG TCGAAGTCTG CCGTGCAGAA CAAAGTGGTG 
GTCATCACAG ATGCCATCTC AGGACTGGGA AAGGAGTGTG CTCGGGTGTT CCATGCAGGT 
GGGGCAAGGC TGGTGCTGTG TGGAAAGAAC TGGGAGGGAC TGGAGAGCCT CTATGCCACC 
TTGACCAGTG TGGCTGACCC CAGCAAGACA TTCACCCCCA AGCTGGTCCT CCTGGATCTC 
TCAGACATTA GCTGTGTTCA AGATGTGGCC AAAGAGGTCC TGGACTGCTA CGGCTGTGTG 
GACATCCTCA TCAACAATGC CAGCGTGAAA GTGAAGGGGC CTGCCCACAA GATTTCCCTG 
GAGCTTGACA AAAAGATCAT GGATGCCAAC TACTTCGGAC CCATCACTTT AACCAAAGTT 
CTGCTTCCCA ACATGATCTC CAGGAGAACA GGCCAGATTG TGTTAGTGAA CAACATCCAA 
GCGAAGTTTG GAATCCCGTT CCGCACAGCT TATGCAGCTT CTAAGCATGC CGTCATGGGC 
TTCTTTGACT GCCTCCGAGC CGAGGTTGAG GAATACGATG TTGTGGTCAG CACCGTGAGC 
CCAACTTTCA TCCGCTCCTA CCGTGCTTCC CCTGAGCAAA GAAACTGGGA GACATCCATT 
TGTAAATTCT TCTGCAGGAA GCTAGCCTAT GGCGTGCACC CGGTGGAGGT GGCTGAGGAA 
GTGATGCGCA CAGTACGGAG GAAGAAGCAA GAGGTGTTCA TGGCCAACCC GGTCCCCAAG 
GCTGCCGTGT TCATCCGCAC CTTCTTCCCT GAGTTCTTCT TCGCTGTGGT GGCCTGTGGG 
GTGAAGGAGA AGCTCAATGT CCCAGAAGAG GGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001013031.2
CDS	140..1075
Translation	MGLMAVLMLPLLLLGISGLLFIYQEASRLWSKSAVQNKVVVITDAISGLGKECARVFHAGGARLVLCGKNWEGLESLYATLTSVADPSKTFTPKLVLLDLSDISCVQDVAKEVLDCYGCVDILINNASVKVKGPAHKISLELDKKIMDANYFGPITLTKVLLPNMISRRTGQIVLVNNIQAKFGIPFRTAYAASKHAVMGFFDCLRAEVEEYDVVVSTVSPTFIRSYRASPEQRNWETSICKFFCRKLAYGVHPVEVAEEVMRTVRRKKQEVFMANPVPKAAVFIRTFFPEFFFAVVACGVKEKLNVPEEG

Target ORF information:

RefSeq Version	NM_001013013.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus dehydrogenase/reductase (SDR family) member 7C (Dhrs7c), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001013013.2

ORF Insert Sequence:

ATGGGGCTCA TGGCTGTCCT GATGCTACCC CTGCTGCTGC TGGGAATCAG CGGCCTCCTC 
TTCATTTACC AGGAGGCATC CAGGCTGTGG TCGAAGTCTG CCGTGCAGAA CAAAGTGGTG 
GTCATCACAG ATGCCATCTC AGGACTGGGA AAGGAGTGTG CTCGGGTGTT CCATGCAGGT 
GGGGCAAGGC TGGTGCTGTG TGGAAAGAAC TGGGAGGGAC TGGAGAGCCT CTATGCCACC 
TTGACCAGTG TGGCTGACCC CAGCAAGACA TTCACCCCCA AGCTGGTCCT CCTGGATCTC 
TCAGACATTA GCTGTGTTCA AGATGTGGCC AAAGAGGTCC TGGACTGCTA CGGCTGTGTG 
GACATCCTCA TCAACAATGC CAGCGTGAAA GTGAAGGGGC CTGCCCACAA GATTTCCCTG 
GAGCTTGACA AAAAGATCAT GGATGCCAAC TACTTCGGAC CCATCACTTT AACCAAAGTT 
CTGCTTCCCA ACATGATCTC CAGGAGAACA GGCCAGATTG TGTTAGTGAA CAACATCCAA 
GCGAAGTTTG GAATCCCGTT CCGCACAGCT TATGCAGCTT CTAAGCATGC CGTCATGGGC 
TTCTTTGACT GCCTCCGAGC CGAGGTTGAG GAATACGATG TTGTGGTCAG CACCGTGAGC 
CCAACTTTCA TCCGCTCCTA CCGTGCTTCC CCTGAGCAAA GAAACTGGGA GACATCCATT 
TGTAAATTCT TCTGCAGGAA GCTAGCCTAT GGCGTGCACC CGGTGGAGGT GGCTGAGGAA 
GTGATGCGCA CAGTACGGAG GAAGAAGCAA GAGGTGTTCA TGGCCAACCC GGTCCCCAAG 
GCTGCCGTGT TCATCCGCAC CTTCTTCCCT GAGTTCTTCT TCGCTGTGGT GGCCTGTGGG 
GTGAAGGAGA AGCTCAATGT CCCAGAAGAG GGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Over-expression of a retinol dehydrogenase (SRP35/DHRS7C) in skeletal muscle activates mTORC2, enhances glucose metabolism and muscle performance.
Scientific reports8(1)636(2018 Jan)
Ruiz A,Dror E,Handschin C,Furrer R,Perez-Schindler J,Bachmann C,Treves S,Zorzato F

Functional loss of DHRS7C induces intracellular Ca2+ overload and myotube enlargement in C2C12 cells via calpain activation.
American journal of physiology. Cell physiology312(1)C29-C39(2017 Jan)
Arai S,Ikeda M,Ide T,Matsuo Y,Fujino T,Hirano K,Sunagawa K,Tsutsui H

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

Dhrs7c cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報