Erp29 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Erp29
Entrez Gene ID	67397
Full Name	endoplasmic reticulum protein 29
Synonyms	1200015M03Rik,2810446M09Rik,AW209030,Erp28,Erp31,PDI-Db
General protein information	Preferred Names endoplasmic reticulum protein 29 Names endoplasmic reticulum resident protein 29
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 5 Map Location: 5\|5 F

mRNA and Protein(s)

mRNA	Protein	Name
NM_026129.2	NP_080405.1	endoplasmic reticulum resident protein 29 precursor

Pathways from BioSystems

Homologies

Bos taurus (cattle)	ERP29	NP_001069739.1
Pan troglodytes (chimpanzee)	ERP29	XP_001139225.2
	ERP29	XP_001109649.1
Canis lupus familiaris (dog)	ERP29	XP_005636567.1
Rattus norvegicus (Norway rat)	Erp29	NP_446413.1
Drosophila melanogaster (fruit fly)	wbl	NP_725867.1
Xenopus tropicalis (tropical clawed frog)	erp29	XP_002940171.2
Homo sapiens (human)	ERP29	NP_006808.1
Mus musculus (house mouse)	Erp29	NP_080405.1
Gallus gallus (chicken)	ERP29	NP_001263253.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP000395	XP_310706.3

Gene Ontology
Bibliography

Related articles in PubMed

Proteomic identification of ERP29 as a key chemoresistant factor activated by the aggregating p53 mutant Arg282Trp.
Zhang Y, Hu Y, Wang JL, Yao H, Wang H, Liang L, Li C, Shi H, Chen Y, Fang JY, Xu J
Oncogene36(39)5473-5483(2017 Sep)

Endoplasmic reticulum protein 29 is involved in endoplasmic reticulum stress in islet beta cells.
Gao J, Zhang Y, Wang L, Xia L, Lu M, Zhang B, Chen Y, He L
Molecular medicine reports13(1)398-402(2016 Jan)

The tissue-specific transcriptomic landscape of the mid-gestational mouse embryo.
Werber M, Wittler L, Timmermann B, Grote P, Herrmann BG
Development (Cambridge, England)141(11)2325-30(2014 Jun)

ERp29 deficiency affects sensitivity to apoptosis via impairment of the ATF6-CHOP pathway of stress response.
Hirsch I, Weiwad M, Prell E, Ferrari DM
Apoptosis : an international journal on programmed cell death19(5)801-15(2014 May)

ERp29 regulates response to doxorubicin by a PERK-mediated mechanism.
Farmaki E, Mkrtchian S, Papazian I, Papavassiliou AG, Kiaris H
Biochimica et biophysica acta1813(6)1165-71(2011 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The anti-aggregation peptide ReACp53 significantly decreased ERP29 expression and suppressed the chemoresistant effect. These findings highlight a role of ERP29 in the acquired chemoresistance of cancer cells expressing the aggregating p53 mutant Arg282Trp.
Title: Proteomic identification of ERP29 as a key chemoresistant factor activated by the aggregating p53 mutant Arg282Trp.

Erp29 may have an important role in Endoplasmic reticulum stress in islet beta cells.
Title: Endoplasmic reticulum protein 29 is involved in endoplasmic reticulum stress in islet beta cells.

ERp29 acts as an escort factor for ATF6 and promotes its transport from ER to Golgi apparatus under ER stress conditions.
Title: ERp29 deficiency affects sensitivity to apoptosis via impairment of the ATF6-CHOP pathway of stress response.

Results identify ERp29 as a novel regulator of PERK and provide evidence for the role of ER resident factors in the regulation of chemotherapeutic efficacy.
Title: ERp29 regulates response to doxorubicin by a PERK-mediated mechanism.

A network of endoplasmic reticulum ERp57, ERp72, and ERp29 facilitate polyomavirus infection.
Title: A PDI family network acts distinctly and coordinately with ERp29 to facilitate polyomavirus infection.

The following Erp29 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Erp29 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu01634	NM_026129.2 Latest version!	Mus musculus endoplasmic reticulum protein 29 (Erp29), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Erp29 ( NM_026129.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_080405.1 Mus musculus endoplasmic reticulum protein 29 (Erp29), mRNA.

Price & Availability↑

CloneID	OMu01634
Clone ID Related Accession (Same CDS sequence)	NM_026129.2
Accession Version	NM_026129.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 789bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Mus musculus(house mouse)
Product	endoplasmic reticulum resident protein 29 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC017125.1. On Jun 19, 2003 this sequence version replaced NM_026129.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC017125.1, AK168112.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849386, SAMN00849389 [ECO:0000348] ##Evidence-Data-END##

ATGGCCGCCG CCGCCGGGGT GTCTGGCGCT GCTTCTCTCT CCCCACTGCT GTCCGTGCTC 
CTGGGCCTGC TGCTCCTCTT TGCTCCGCAC GGCGGCAGCG GCCTACACAC GAAGGGTGCC 
CTTCCCTTGG ACACAGTCAC TTTCTACAAG GTCATTCCCA AAAGCAAGTT CGTCTTGGTG 
AAGTTCGACA CCCAGTACCC CTATGGAGAG AAGCAAGATG AGTTCAAGCG TCTGGCTGAG 
AACTCAGCCT CCAGCGAGGA GCTCTTGGTG GCAGAGGTGG GGATCTCAGA CTATGGCGAC 
AAGCTGAACA TGGAGCTGAG TGAGAAGTAC AAGCTGGACA AGGAGAGCTA CCCAGTCTTC 
TACCTATTCC GGGATGGGGA CTTGGAGAAC CCTGTGCTGT ACAATGGGGC AGTTAAGGTT 
GGAGCCATCC AGCGCTGGCT AAAGGGGCAG GGGGTCTACC TGGGCATGCC TGGGTGCCTG 
CCTGCATACG ATGCCCTGGC AGGCGAGTTC ATCAAGGCCT CCAGCATAGA GGCCCGACAG 
GCCATCTTGA AACAGGGACA GGATGGCCTC CTAAGTGTGA AGGAAACAGA GAAGAAGTGG 
GCTAGCCAAT ACCTGAAGAT CATGGGGAAG ATCCTGGACC AAGGTGAGGA CTTTCCAGCC 
TCTGAGATGG CCCGGATCGG TAAGCTGATA GAGAACAAGA TGAGTGACAG CAAGAAAGAA 
GAGCTACAGA AGAGCTTAAA CATCCTGACG GCCTTCCGGA AGAAGGAGGC TGAGAAGGAG 
GAGCTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_080405.1
CDS	135..923
Translation	MAAAAGVSGAASLSPLLSVLLGLLLLFAPHGGSGLHTKGALPLDTVTFYKVIPKSKFVLVKFDTQYPYGEKQDEFKRLAENSASSEELLVAEVGISDYGDKLNMELSEKYKLDKESYPVFYLFRDGDLENPVLYNGAVKVGAIQRWLKGQGVYLGMPGCLPAYDALAGEFIKASSIEARQAILKQGQDGLLSVKETEKKWASQYLKIMGKILDQGEDFPASEMARIGKLIENKMSDSKKEELQKSLNILTAFRKKEAEKEEL

Target ORF information:

RefSeq Version	NM_026129.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus endoplasmic reticulum protein 29 (Erp29), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_026129.2

ORF Insert Sequence:

ATGGCCGCCG CCGCCGGGGT GTCTGGCGCT GCTTCTCTCT CCCCACTGCT GTCCGTGCTC 
CTGGGCCTGC TGCTCCTCTT TGCTCCGCAC GGCGGCAGCG GCCTACACAC GAAGGGTGCC 
CTTCCCTTGG ACACAGTCAC TTTCTACAAG GTCATTCCCA AAAGCAAGTT CGTCTTGGTG 
AAGTTCGACA CCCAGTACCC CTATGGAGAG AAGCAAGATG AGTTCAAGCG TCTGGCTGAG 
AACTCAGCCT CCAGCGAGGA GCTCTTGGTG GCAGAGGTGG GGATCTCAGA CTATGGCGAC 
AAGCTGAACA TGGAGCTGAG TGAGAAGTAC AAGCTGGACA AGGAGAGCTA CCCAGTCTTC 
TACCTATTCC GGGATGGGGA CTTGGAGAAC CCTGTGCTGT ACAATGGGGC AGTTAAGGTT 
GGAGCCATCC AGCGCTGGCT AAAGGGGCAG GGGGTCTACC TGGGCATGCC TGGGTGCCTG 
CCTGCATACG ATGCCCTGGC AGGCGAGTTC ATCAAGGCCT CCAGCATAGA GGCCCGACAG 
GCCATCTTGA AACAGGGACA GGATGGCCTC CTAAGTGTGA AGGAAACAGA GAAGAAGTGG 
GCTAGCCAAT ACCTGAAGAT CATGGGGAAG ATCCTGGACC AAGGTGAGGA CTTTCCAGCC 
TCTGAGATGG CCCGGATCGG TAAGCTGATA GAGAACAAGA TGAGTGACAG CAAGAAAGAA 
GAGCTACAGA AGAGCTTAAA CATCCTGACG GCCTTCCGGA AGAAGGAGGC TGAGAAGGAG 
GAGCTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Proteomic identification of ERP29 as a key chemoresistant factor activated by the aggregating p53 mutant Arg282Trp.
Oncogene36(39)5473-5483(2017 Sep)
Zhang Y,Hu Y,Wang JL,Yao H,Wang H,Liang L,Li C,Shi H,Chen Y,Fang JY,Xu J

Endoplasmic reticulum protein 29 is involved in endoplasmic reticulum stress in islet beta cells.
Molecular medicine reports13(1)398-402(2016 Jan)
Gao J,Zhang Y,Wang L,Xia L,Lu M,Zhang B,Chen Y,He L

The tissue-specific transcriptomic landscape of the mid-gestational mouse embryo.
Development (Cambridge, England)141(11)2325-30(2014 Jun)
Werber M,Wittler L,Timmermann B,Grote P,Herrmann BG

ERp29 deficiency affects sensitivity to apoptosis via impairment of the ATF6-CHOP pathway of stress response.
Apoptosis : an international journal on programmed cell death19(5)801-15(2014 May)
Hirsch I,Weiwad M,Prell E,Ferrari DM

ERp29 regulates response to doxorubicin by a PERK-mediated mechanism.
Biochimica et biophysica acta1813(6)1165-71(2011 Jun)
Farmaki E,Mkrtchian S,Papazian I,Papavassiliou AG,Kiaris H

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Erp29 cDNA ORF clone, Mus musculus(house mouse)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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