Myoz1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Myoz1
Entrez Gene ID	59011
Full Name	myozenin 1
Synonyms	2310001N11Rik,AV090278,FATZ,Myoz
General protein information	Preferred Names myozenin 1 Names myozenin-1 calcineurin-2 calsarcin-2 filamin-, actinin- and telethonin-binding protein myoz1 skeletal muscle-specific protein
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 14 Map Location: 14\|14 A3

mRNA and Protein(s)

mRNA	Protein	Name
NM_021508.3	NP_067483.1	myozenin-1

Pathways from BioSystems

Homologies

Xenopus tropicalis (tropical clawed frog)	myoz1	NP_001006717.1
Pan troglodytes (chimpanzee)	MYOZ1	XP_001143094.1
Mus musculus (house mouse)	Myoz1	NP_067483.1
Homo sapiens (human)	MYOZ1	NP_067068.1
	MYOZ1	XP_001100978.1
Bos taurus (cattle)	MYOZ1	NP_776822.1
Rattus norvegicus (Norway rat)	Myoz1	NP_001102567.1
Gallus gallus (chicken)	MYOZ1	XP_421619.3
Danio rerio (zebrafish)	myoz1b	NP_001002447.1
Canis lupus familiaris (dog)	MYOZ1	NP_001041560.1
Danio rerio (zebrafish)	myoz1a	NP_991241.1

Gene Ontology
Bibliography

Related articles in PubMed

Targeting of miR-432 to myozenin1 to regulate myoblast proliferation and differentiation.
Ren RM, Liu H, Zhao SH, Cao JH
Genetics and molecular research : GMR15(4)(2016 Dec)

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)

Abnormal Mammary Development in 129:STAT1-Null Mice is Stroma-Dependent.
Chen JQ, Mori H, Cardiff RD, Trott JF, Hovey RC, Hubbard NE, Engelberg JA, Tepper CG, Willis BJ, Khan IH, Ravindran RK, Chan SR, Schreiber RD, Borowsky AD
PloS one10(6)e0129895(2015)

Genesis of muscle fiber-type diversity during mouse embryogenesis relies on Six1 and Six4 gene expression.
Richard AF, Demignon J, Sakakibara I, Pujol J, Favier M, Strochlic L, Le Grand F, Sgarioto N, Guernec A, Schmitt A, Cagnard N, Huang R, Legay C, Guillet-Deniau I, Maire P
Developmental biology359(2)303-20(2011 Nov)

Calsarcin-2 deficiency increases exercise capacity in mice through calcineurin/NFAT activation.
Frey N, Frank D, Lippl S, Kuhn C, K?gler H, Barrientos T, Rohr C, Will R, M?ller OJ, Weiler H, Bassel-Duby R, Katus HA, Olson EN
The Journal of clinical investigation118(11)3598-608(2008 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Results provide insights into the potential functions of miR-432 as well as its proposed target, MYOZ1, during muscle development.
Title: Targeting of miR-432 to myozenin1 to regulate myoblast proliferation and differentiation.

Calsarcin-2 skeletal muscle specific protein deficiency increases execrcise capacity in mice through calcineurin/NFAT activation.
Title: Calsarcin-2 deficiency increases exercise capacity in mice through calcineurin/NFAT activation.

study defined proximal promoter region of calsarcin-1 (CS-1)& calsarcin-2 (CS-2)genes; data suggest NF-kappaB is required for transcription of CS-1 gene, but not CS-2
Title: NF-kappaB mediates the transcription of mouse calsarcin-1 gene, but not calsarcin-2, in C2C12 cells.

The following Myoz1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Myoz1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu12428	NM_021508.3 Latest version!	Mus musculus myozenin 1 (Myoz1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Myoz1 ( NM_021508.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_067483.1 Mus musculus myozenin 1 (Myoz1), mRNA.

Price & Availability↑

CloneID	OMu12428
Clone ID Related Accession (Same CDS sequence)	NM_021508.3
Accession Version	NM_021508.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 891bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Mus musculus(house mouse)
Product	myozenin-1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY790048.1, AK009077.1, AK041896.1 and AV250577.1. On Mar 23, 2007 this sequence version replaced NM_021508.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK009077.1, AK041896.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849376 [ECO:0000348] ##Evidence-Data-END##

ATGCCACTCT CAGGAACCCC GGCCCCTAAC AAGAGGAGGA AGTCAAGCAA ACTGATTATG 
GAGCTCACTG GAGGTGGCCG GGAGAGCTCA GGCCTGAACC TGGGCAAGAA GATCAGTGTC 
CCAAGGGATG TGATGTTGGA GGAGCTGTCC CTTCTTACCA ACCGAGGCTC CAAGATGTTC 
AAGCTACGGC AGATGCGGGT GGAGAAATTT ATCTATGAGA ATCACCCCGA TGTTTTCTCT 
GACAGCTCAA TGGATCACTT CCAGAAGTTT CTTCCCACAG TGGGAGGACA GCTGGAGACA 
GCTGGTCAGG GCTTCTCATA TGGCAAGGGC AGCAGTGGAG GCCAGGCTGG CAGCAGTGGC 
TCTGCTGGAC AGTATGGCTC TGACCGTCAT CAGCAGGGCT CTGGGTTTGG AGCTGGGGGT 
TCAGGTGGTC CTGGGGGCCA GGCTGGTGGA GGAGGAGCTC CTGGCACAGT AGGGCTTGGA 
GAGCCCGGAT CAGGTGACCA GGCAGGTGGA GATGGAAAAC ATGTCACTGT GTTCAAGACT 
TATATTTCCC CATGGGATCG GGCCATGGGG GTTGATCCTC AGCAAAAAGT GGAACTTGGC 
ATTGACCTAC TGGCATACGG TGCCAAAGCT GAACTCCCCA AATATAAGTC CTTCAACAGG 
ACAGCAATGC CCTACGGTGG ATATGAGAAG GCCTCCAAAC GCATGACCTT CCAGATGCCC 
AAGTTTGACC TGGGGCCTCT GCTGAGTGAA CCCCTGGTCC TCTACAACCA GAACCTCTCC 
AACAGGCCTT CTTTCAATCG AACCCCTATT CCCTGGTTGA GCTCTGGGGA GCATGTAGAC 
TACAACGTGG ATGTTGGTAT CCCCTTGGAT GGAGAGACAG AGGAGCTGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_067483.1
CDS	128..1018
Translation	MPLSGTPAPNKRRKSSKLIMELTGGGRESSGLNLGKKISVPRDVMLEELSLLTNRGSKMFKLRQMRVEKFIYENHPDVFSDSSMDHFQKFLPTVGGQLETAGQGFSYGKGSSGGQAGSSGSAGQYGSDRHQQGSGFGAGGSGGPGGQAGGGGAPGTVGLGEPGSGDQAGGDGKHVTVFKTYISPWDRAMGVDPQQKVELGIDLLAYGAKAELPKYKSFNRTAMPYGGYEKASKRMTFQMPKFDLGPLLSEPLVLYNQNLSNRPSFNRTPIPWLSSGEHVDYNVDVGIPLDGETEEL

Target ORF information:

RefSeq Version	NM_021508.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus myozenin 1 (Myoz1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_021508.3

ORF Insert Sequence:

ATGCCACTCT CAGGAACCCC GGCCCCTAAC AAGAGGAGGA AGTCAAGCAA ACTGATTATG 
GAGCTCACTG GAGGTGGCCG GGAGAGCTCA GGCCTGAACC TGGGCAAGAA GATCAGTGTC 
CCAAGGGATG TGATGTTGGA GGAGCTGTCC CTTCTTACCA ACCGAGGCTC CAAGATGTTC 
AAGCTACGGC AGATGCGGGT GGAGAAATTT ATCTATGAGA ATCACCCCGA TGTTTTCTCT 
GACAGCTCAA TGGATCACTT CCAGAAGTTT CTTCCCACAG TGGGAGGACA GCTGGAGACA 
GCTGGTCAGG GCTTCTCATA TGGCAAGGGC AGCAGTGGAG GCCAGGCTGG CAGCAGTGGC 
TCTGCTGGAC AGTATGGCTC TGACCGTCAT CAGCAGGGCT CTGGGTTTGG AGCTGGGGGT 
TCAGGTGGTC CTGGGGGCCA GGCTGGTGGA GGAGGAGCTC CTGGCACAGT AGGGCTTGGA 
GAGCCCGGAT CAGGTGACCA GGCAGGTGGA GATGGAAAAC ATGTCACTGT GTTCAAGACT 
TATATTTCCC CATGGGATCG GGCCATGGGG GTTGATCCTC AGCAAAAAGT GGAACTTGGC 
ATTGACCTAC TGGCATACGG TGCCAAAGCT GAACTCCCCA AATATAAGTC CTTCAACAGG 
ACAGCAATGC CCTACGGTGG ATATGAGAAG GCCTCCAAAC GCATGACCTT CCAGATGCCC 
AAGTTTGACC TGGGGCCTCT GCTGAGTGAA CCCCTGGTCC TCTACAACCA GAACCTCTCC 
AACAGGCCTT CTTTCAATCG AACCCCTATT CCCTGGTTGA GCTCTGGGGA GCATGTAGAC 
TACAACGTGG ATGTTGGTAT CCCCTTGGAT GGAGAGACAG AGGAGCTGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Targeting of miR-432 to myozenin1 to regulate myoblast proliferation and differentiation.
Genetics and molecular research : GMR15(4)(2016 Dec)
Ren RM,Liu H,Zhao SH,Cao JH

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie SM,Fuchs H,Gailus-Durner V,Galli A,Gambadoro A,Gallegos J,Guo S,Horner NR,Hsu CW,Johnson SJ,Kalaga S,Keith LC,Lanoue L,Lawson TN,Lek M,Mark M,Marschall S,Mason J,McElwee ML,Newbigging S,Nutter LM,Peterson KA,Ramirez-Solis R,Rowland DJ,Ryder E,Samocha KE,Seavitt JR,Selloum M,Szoke-Kovacs Z,Tamura M,Trainor AG,Tudose I,Wakana S,Warren J,Wendling O,West DB,Wong L,Yoshiki A,,,,,,,,,MacArthur DG,Tocchini-Valentini GP,Gao X,Flicek P,Bradley A,Skarnes WC,Justice MJ,Parkinson HE,Moore M,Wells S,Braun RE,Svenson KL,de Angelis MH,Herault Y,Mohun T,Mallon AM,Henkelman RM,Brown SD,Adams DJ,Lloyd KC,McKerlie C,Beaudet AL,Bu?an M,Murray SA

Abnormal Mammary Development in 129:STAT1-Null Mice is Stroma-Dependent.
PloS one10(6)e0129895(2015)
Chen JQ,Mori H,Cardiff RD,Trott JF,Hovey RC,Hubbard NE,Engelberg JA,Tepper CG,Willis BJ,Khan IH,Ravindran RK,Chan SR,Schreiber RD,Borowsky AD

Genesis of muscle fiber-type diversity during mouse embryogenesis relies on Six1 and Six4 gene expression.
Developmental biology359(2)303-20(2011 Nov)
Richard AF,Demignon J,Sakakibara I,Pujol J,Favier M,Strochlic L,Le Grand F,Sgarioto N,Guernec A,Schmitt A,Cagnard N,Huang R,Legay C,Guillet-Deniau I,Maire P

Calsarcin-2 deficiency increases exercise capacity in mice through calcineurin/NFAT activation.
The Journal of clinical investigation118(11)3598-608(2008 Nov)
Frey N,Frank D,Lippl S,Kuhn C,K?gler H,Barrientos T,Rohr C,Will R,M?ller OJ,Weiler H,Bassel-Duby R,Katus HA,Olson EN

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Myoz1 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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