Pias1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Pias1
Entrez Gene ID	56469
Full Name	protein inhibitor of activated STAT 1
Synonyms	2900068C24Rik,Ddxbp1,GBP
General protein information	Preferred Names protein inhibitor of activated STAT 1 Names E3 SUMO-protein ligase PIAS1 DEAD/H (Asp-Glu-Ala-Asp/His) box binding protein 1 DEAD/H box-binding protein 1 RING-type E3 ubiquitin transferase PIAS1 protein inhibitor of activated STAT protein 1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 9 Map Location: 9\|9 B

mRNA and Protein(s)

mRNA	Protein	Name
NM_019663.3	NP_062637.2	E3 SUMO-protein ligase PIAS1
XM_006511302.3	XP_006511365.1	E3 SUMO-protein ligase PIAS1 isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	PIAS1	NP_057250.1
Canis lupus familiaris (dog)	PIAS1	XP_535524.2
Bos taurus (cattle)	PIAS1	NP_001068864.1
Mus musculus (house mouse)	Pias1	NP_062637.2
Pan troglodytes (chimpanzee)	PIAS1	XP_523109.3
Drosophila melanogaster (fruit fly)	Su(var)2-10	NP_001188888.1
	PIAS1	XP_001082929.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP005031	XP_313897.4
Rattus norvegicus (Norway rat)	Pias1	NP_001100299.2
Gallus gallus (chicken)	PIAS1	NP_001026627.1
Xenopus tropicalis (tropical clawed frog)	pias1	XP_002932990.1

Gene Ontology
Bibliography

Related articles in PubMed

Foxp1 regulation of neonatal vocalizations via cortical development.
Usui N, Araujo DJ, Kulkarni A, Co M, Ellegood J, Harper M, Toriumi K, Lerch JP, Konopka G
Genes & development31(20)2039-2055(2017 Oct)

Pias1 is essential for erythroid and vascular development in the mouse embryo.
Constanzo JD, Deng M, Rindhe S, Tang KJ, Zhang CC, Scaglioni PP
Developmental biology415(1)98-110(2016 07)

PIAS1 Promotes Lymphomagenesis through MYC Upregulation.
Rabellino A, Melegari M, Tompkins VS, Chen W, Van Ness BG, Teruya-Feldstein J, Conacci-Sorrell M, Janz S, Scaglioni PP
Cell reports15(10)2266-2278(2016 06)

PIAS1 Regulates Mutant Huntingtin Accumulation and Huntington's Disease-Associated Phenotypes In?Vivo.
Ochaba J, Monteys AM, O'Rourke JG, Reidling JC, Steffan JS, Davidson BL, Thompson LM
Neuron90(3)507-20(2016 05)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Pias1 expression in primary myoblasts enhances the induction of cardiac muscle genes MyoD, Myogenin and Myomaker. Endothelial cell specific inactivation of Pias1 in vivo impairs yolk sac erythrogenesis, angiogenesis and recapitulates loss of myocardium muscle mass. Pias1 is an essential gene for YS erythropoiesis and vasculogenesis in vivo.
Title: Pias1 is essential for erythroid and vascular development in the mouse embryo.

these results indicate that PIAS1 is a positive regulator of MYC.
Title: PIAS1 Promotes Lymphomagenesis through MYC Upregulation.

PIAS1 overexpression exacerbated mutant Huntingtin-associated phenotypes and aberrant protein accumulation
Title: PIAS1 Regulates Mutant Huntingtin Accumulation and Huntington's Disease-Associated Phenotypes In?Vivo.

Data suggest overexpression of Pias1 in white adipose tissue (WAT) of obesity/prediabetes improves insulin resistance; knockdown of Pias1 in normal WAT leads to insulin resistance; Pias1 expression in WAT is down-regulated by c-Jun N-terminal kinase.
Title: Protein Inhibitor of Activated STAT 1 (PIAS1) Protects Against Obesity-Induced Insulin Resistance by Inhibiting Inflammation Cascade in Adipose Tissue.

Between the E3 SUMO ligase PIAS1 and STAT-3.
Title: PIAS1 and STAT-3 impair the tumoricidal potential of IFN-?-stimulated mouse dendritic cells generated with IL-15.

The following Pias1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Pias1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu42885	XM_006511302.3 Latest version!	Mus musculus protein inhibitor of activated STAT 1 (Pias1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$307.30 $439.00
OMu21992	NM_019663.3 Latest version!	Mus musculus protein inhibitor of activated STAT 1 (Pias1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$384.30 $549.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Pias1 ( XM_006511302.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006511365.1 Mus musculus protein inhibitor of activated STAT 1 (Pias1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu42885
Clone ID Related Accession (Same CDS sequence)	XM_006511302.3
Accession Version	XM_006511302.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1929bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	E3 SUMO-protein ligase PIAS1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000075.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006511302.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTTATGA GCCTTAGAGT TTCTGAACTC CAAGTACTGT TGGGCTACGC TGGGAGGAAC 
AAGCACGGAC GCAAACACGA ACTTCTTACA AAAGCCCTGC ATTTGTTAAA GGCTGGCTGT 
AGTCCTGCTG TACAAATGAA AATTAAAGAA CTCTACAGGA GGCGGTTCCC TCAGAAAATT 
ATGACGCCTG CGGACTTGTC TATCCCCAAC GTACATTCAA GTCCTATGCC TCCGACTCTT 
TCTCCATCCA CCATTCCACA GCTCACTTAT GATGGCCACC CTGCATCATC CCCACTACTC 
CCTGTTTCTC TTCTGGGACC CAAACATGAA CTGGAACTCC CACATCTCAC GTCAGCGCTG 
CACCCAGTCC ACCCGGACAT AAAGCTGCAG AAGCTACCAT TCTATGACCT GTTGGATGAA 
CTGATCAAGC CCACCAGTCT AGCTTCAGAC AACAGCCAGC GCTTTCGGGA AACCTGTTTT 
GCATTTGCCT TGACACCACA ACAGGTGCAG CAGATCAGCA GCTCCATGGA TATTTCTGGG 
ACCAAATGTG ACTTCACAGT GCAGGTCCAA TTAAGGTTTT GTTTATCAGA AACCAGTTGT 
CCACAAGAAG ATCACTTCCC ACCCAACCTT TGTGTAAAAG TGAATACAAA ACCTTGCAGC 
CTTCCAGGTT ACCTTCCACC TACTAAAAAC GGTGTGGAAC CAAAGCGACC TAGCCGACCA 
ATTAATATCA CCTCACTTGT CCGATTGTCC ACGACAGTAC CAAATACCAT TGTTGTTTCT 
TGGACTGCAG AAATTGGAAG AACCTATTCC ATGGCAGTAT ATCTTGTAAA ACAGTTGTCC 
TCAACAGTTC TTCTTCAGAG GTTACGAGCA AAGGGAATAA GGAATCCGGA TCATTCTAGA 
GCTTTAATTA AAGAGAAGTT AACTGCAGAT CCAGATAGTG AGATAGCTAC TACCAGCCTA 
CGGGTTTCGC TGCTGTGTCC ACTTGGGAAA ATGCGACTGA CAATCCCCTG TCGGGCACTT 
ACCTGCTCCC ACCTTCAGTG TTTTGATGCA ACTCTTTACA TTCAAATGAA TGAGAAAAAA 
CCAACATGGG TTTGTCCTGT CTGTGATAAG AAGGCCCCAT ATGAACACCT TATTATTGAC 
GGGTTGTTTA TGGAAATTCT AAAGTACTGC ACAGACTGTG ACGAGATACA GTTTAAGGAG 
GATGGCTCGT GGGCTCCAAT GAGGTCAAAG AAGGAGGTTC AAGAAGTCAC TGCCTCCTAC 
AATGGAGTTG ATGGTTGCTT GAGCTCCACA TTGGAGCATC AGGTAGCGTC CCACAACCAG 
TCCTCAAATA AAAACAAGAA AGTCGAGGTC ATTGACCTAA CCATTGACAG CTCGTCAGAT 
GAAGAGGAGG AAGAACCCCC TGCCAAGAGG ACCTGTCCTT CCCTGTCTCC TACGTCACCA 
CTAAGTAATA AAGGCATTTT AAGTCTTCCT CATCAAGCCT CGCCTGTGTC CCGCACCCCA 
AGCCTTCCTG CTGTAGATAC AAGCTACATC AACACCTCCC TCATCCAGGA CTACAGGCAC 
CCCTTCCACA TGACGCCTAT GCCTTATGAC TTACAAGGAT TAGATTTCTT TCCTTTCTTA 
TCAGGAGACA ATCAGCATTA CAACACCTCC CTGCTAGCCG CAGCTGCAGC GGCGGTCTCA 
GATGACCAGG ACCTCCTGCA CTCCTCCCGG TTTTTCCCGT ATACCTCCTC GCAGATGTTT 
CTCGACCAGC TAAGTGCAGG AGGGAGCACA TCTCTGCCAG CCACCAACGG AAGCAGTAGC 
GGCAGCAACA GCAGCCTTGT GTCTTCCAAC AGTCTGAGAG AGAGCCATGG CCATGGTGTG 
GCCAGCAGGA GCAGCGCAGA CACAGCGTCC ATCTTTGGCA TCATACCAGA CATTATCTCA 
TTGGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006511365.1
CDS	492..2420
Translation	MVMSLRVSELQVLLGYAGRNKHGRKHELLTKALHLLKAGCSPAVQMKIKELYRRRFPQKIMTPADLSIPNVHSSPMPPTLSPSTIPQLTYDGHPASSPLLPVSLLGPKHELELPHLTSALHPVHPDIKLQKLPFYDLLDELIKPTSLASDNSQRFRETCFAFALTPQQVQQISSSMDISGTKCDFTVQVQLRFCLSETSCPQEDHFPPNLCVKVNTKPCSLPGYLPPTKNGVEPKRPSRPINITSLVRLSTTVPNTIVVSWTAEIGRTYSMAVYLVKQLSSTVLLQRLRAKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLLCPLGKMRLTIPCRALTCSHLQCFDATLYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILKYCTDCDEIQFKEDGSWAPMRSKKEVQEVTASYNGVDGCLSSTLEHQVASHNQSSNKNKKVEVIDLTIDSSSDEEEEEPPAKRTCPSLSPTSPLSNKGILSLPHQASPVSRTPSLPAVDTSYINTSLIQDYRHPFHMTPMPYDLQGLDFFPFLSGDNQHYNTSLLAAAAAAVSDDQDLLHSSRFFPYTSSQMFLDQLSAGGSTSLPATNGSSSGSNSSLVSSNSLRESHGHGVASRSSADTASIFGIIPDIISLD

Target ORF information:

RefSeq Version	XM_006511302.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus protein inhibitor of activated STAT 1 (Pias1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006511302.3

ORF Insert Sequence:

ATGGTTATGA GCCTTAGAGT TTCTGAACTC CAAGTACTGT TGGGCTACGC TGGGAGGAAC 
AAGCACGGAC GCAAACACGA ACTTCTTACA AAAGCCCTGC ATTTGTTAAA GGCTGGCTGT 
AGTCCTGCTG TACAAATGAA AATTAAAGAA CTCTACAGGA GGCGGTTCCC TCAGAAAATT 
ATGACGCCTG CGGACTTGTC TATCCCCAAC GTACATTCAA GTCCTATGCC TCCGACTCTT 
TCTCCATCCA CCATTCCACA GCTCACTTAT GATGGCCACC CTGCATCATC CCCACTACTC 
CCTGTTTCTC TTCTGGGACC CAAACATGAA CTGGAACTCC CACATCTCAC GTCAGCGCTG 
CACCCAGTCC ACCCGGACAT AAAGCTGCAG AAGCTACCAT TCTATGACCT GTTGGATGAA 
CTGATCAAGC CCACCAGTCT AGCTTCAGAC AACAGCCAGC GCTTTCGGGA AACCTGTTTT 
GCATTTGCCT TGACACCACA ACAGGTGCAG CAGATCAGCA GCTCCATGGA TATTTCTGGG 
ACCAAATGTG ACTTCACAGT GCAGGTCCAA TTAAGGTTTT GTTTATCAGA AACCAGTTGT 
CCACAAGAAG ATCACTTCCC ACCCAACCTT TGTGTAAAAG TGAATACAAA ACCTTGCAGC 
CTTCCAGGTT ACCTTCCACC TACTAAAAAC GGTGTGGAAC CAAAGCGACC TAGCCGACCA 
ATTAATATCA CCTCACTTGT CCGATTGTCC ACGACAGTAC CAAATACCAT TGTTGTTTCT 
TGGACTGCAG AAATTGGAAG AACCTATTCC ATGGCAGTAT ATCTTGTAAA ACAGTTGTCC 
TCAACAGTTC TTCTTCAGAG GTTACGAGCA AAGGGAATAA GGAATCCGGA TCATTCTAGA 
GCTTTAATTA AAGAGAAGTT AACTGCAGAT CCAGATAGTG AGATAGCTAC TACCAGCCTA 
CGGGTTTCGC TGCTGTGTCC ACTTGGGAAA ATGCGACTGA CAATCCCCTG TCGGGCACTT 
ACCTGCTCCC ACCTTCAGTG TTTTGATGCA ACTCTTTACA TTCAAATGAA TGAGAAAAAA 
CCAACATGGG TTTGTCCTGT CTGTGATAAG AAGGCCCCAT ATGAACACCT TATTATTGAC 
GGGTTGTTTA TGGAAATTCT AAAGTACTGC ACAGACTGTG ACGAGATACA GTTTAAGGAG 
GATGGCTCGT GGGCTCCAAT GAGGTCAAAG AAGGAGGTTC AAGAAGTCAC TGCCTCCTAC 
AATGGAGTTG ATGGTTGCTT GAGCTCCACA TTGGAGCATC AGGTAGCGTC CCACAACCAG 
TCCTCAAATA AAAACAAGAA AGTCGAGGTC ATTGACCTAA CCATTGACAG CTCGTCAGAT 
GAAGAGGAGG AAGAACCCCC TGCCAAGAGG ACCTGTCCTT CCCTGTCTCC TACGTCACCA 
CTAAGTAATA AAGGCATTTT AAGTCTTCCT CATCAAGCCT CGCCTGTGTC CCGCACCCCA 
AGCCTTCCTG CTGTAGATAC AAGCTACATC AACACCTCCC TCATCCAGGA CTACAGGCAC 
CCCTTCCACA TGACGCCTAT GCCTTATGAC TTACAAGGAT TAGATTTCTT TCCTTTCTTA 
TCAGGAGACA ATCAGCATTA CAACACCTCC CTGCTAGCCG CAGCTGCAGC GGCGGTCTCA 
GATGACCAGG ACCTCCTGCA CTCCTCCCGG TTTTTCCCGT ATACCTCCTC GCAGATGTTT 
CTCGACCAGC TAAGTGCAGG AGGGAGCACA TCTCTGCCAG CCACCAACGG AAGCAGTAGC 
GGCAGCAACA GCAGCCTTGT GTCTTCCAAC AGTCTGAGAG AGAGCCATGG CCATGGTGTG 
GCCAGCAGGA GCAGCGCAGA CACAGCGTCC ATCTTTGGCA TCATACCAGA CATTATCTCA 
TTGGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Pias1 ( NM_019663.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_062637.2 Mus musculus protein inhibitor of activated STAT 1 (Pias1), mRNA.

Price & Availability↑

CloneID	OMu21992
Clone ID Related Accession (Same CDS sequence)	NM_019663.3
Accession Version	NM_019663.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1956bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-03
Organism	Mus musculus(house mouse)
Product	E3 SUMO-protein ligase PIAS1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AK075708.1. On Apr 6, 2007 this sequence version replaced NM_019663.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK075708.1, SRR1660815.178947.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164142 [ECO:0000348] ##Evidence-Data-END##

ATGGCGGACA GTGCGGAACT AAAGCAAATG GTTATGAGCC TTAGAGTTTC TGAACTCCAA 
GTACTGTTGG GCTACGCTGG GAGGAACAAG CACGGACGCA AACACGAACT TCTTACAAAA 
GCCCTGCATT TGTTAAAGGC TGGCTGTAGT CCTGCTGTAC AAATGAAAAT TAAAGAACTC 
TACAGGAGGC GGTTCCCTCA GAAAATTATG ACGCCTGCGG ACTTGTCTAT CCCCAACGTA 
CATTCAAGTC CTATGCCTCC GACTCTTTCT CCATCCACCA TTCCACAGCT CACTTATGAT 
GGCCACCCTG CATCATCCCC ACTACTCCCT GTTTCTCTTC TGGGACCCAA ACATGAACTG 
GAACTCCCAC ATCTCACGTC AGCGCTGCAC CCAGTCCACC CGGACATAAA GCTGCAGAAG 
CTACCATTCT ATGACCTGTT GGATGAACTG ATCAAGCCCA CCAGTCTAGC TTCAGACAAC 
AGCCAGCGCT TTCGGGAAAC CTGTTTTGCA TTTGCCTTGA CACCACAACA GGTGCAGCAG 
ATCAGCAGCT CCATGGATAT TTCTGGGACC AAATGTGACT TCACAGTGCA GGTCCAATTA 
AGGTTTTGTT TATCAGAAAC CAGTTGTCCA CAAGAAGATC ACTTCCCACC CAACCTTTGT 
GTAAAAGTGA ATACAAAACC TTGCAGCCTT CCAGGTTACC TTCCACCTAC TAAAAACGGT 
GTGGAACCAA AGCGACCTAG CCGACCAATT AATATCACCT CACTTGTCCG ATTGTCCACG 
ACAGTACCAA ATACCATTGT TGTTTCTTGG ACTGCAGAAA TTGGAAGAAC CTATTCCATG 
GCAGTATATC TTGTAAAACA GTTGTCCTCA ACAGTTCTTC TTCAGAGGTT ACGAGCAAAG 
GGAATAAGGA ATCCGGATCA TTCTAGAGCT TTAATTAAAG AGAAGTTAAC TGCAGATCCA 
GATAGTGAGA TAGCTACTAC CAGCCTACGG GTTTCGCTGC TGTGTCCACT TGGGAAAATG 
CGACTGACAA TCCCCTGTCG GGCACTTACC TGCTCCCACC TTCAGTGTTT TGATGCAACT 
CTTTACATTC AAATGAATGA GAAAAAACCA ACATGGGTTT GTCCTGTCTG TGATAAGAAG 
GCCCCATATG AACACCTTAT TATTGACGGG TTGTTTATGG AAATTCTAAA GTACTGCACA 
GACTGTGACG AGATACAGTT TAAGGAGGAT GGCTCGTGGG CTCCAATGAG GTCAAAGAAG 
GAGGTTCAAG AAGTCACTGC CTCCTACAAT GGAGTTGATG GTTGCTTGAG CTCCACATTG 
GAGCATCAGG TAGCGTCCCA CAACCAGTCC TCAAATAAAA ACAAGAAAGT CGAGGTCATT 
GACCTAACCA TTGACAGCTC GTCAGATGAA GAGGAGGAAG AACCCCCTGC CAAGAGGACC 
TGTCCTTCCC TGTCTCCTAC GTCACCACTA AGTAATAAAG GCATTTTAAG TCTTCCTCAT 
CAAGCCTCGC CTGTGTCCCG CACCCCAAGC CTTCCTGCTG TAGATACAAG CTACATCAAC 
ACCTCCCTCA TCCAGGACTA CAGGCACCCC TTCCACATGA CGCCTATGCC TTATGACTTA 
CAAGGATTAG ATTTCTTTCC TTTCTTATCA GGAGACAATC AGCATTACAA CACCTCCCTG 
CTAGCCGCAG CTGCAGCGGC GGTCTCAGAT GACCAGGACC TCCTGCACTC CTCCCGGTTT 
TTCCCGTATA CCTCCTCGCA GATGTTTCTC GACCAGCTAA GTGCAGGAGG GAGCACATCT 
CTGCCAGCCA CCAACGGAAG CAGTAGCGGC AGCAACAGCA GCCTTGTGTC TTCCAACAGT 
CTGAGAGAGA GCCATGGCCA TGGTGTGGCC AGCAGGAGCA GCGCAGACAC AGCGTCCATC 
TTTGGCATCA TACCAGACAT TATCTCATTG GACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_062637.2
CDS	9..1964
Translation	MADSAELKQMVMSLRVSELQVLLGYAGRNKHGRKHELLTKALHLLKAGCSPAVQMKIKELYRRRFPQKIMTPADLSIPNVHSSPMPPTLSPSTIPQLTYDGHPASSPLLPVSLLGPKHELELPHLTSALHPVHPDIKLQKLPFYDLLDELIKPTSLASDNSQRFRETCFAFALTPQQVQQISSSMDISGTKCDFTVQVQLRFCLSETSCPQEDHFPPNLCVKVNTKPCSLPGYLPPTKNGVEPKRPSRPINITSLVRLSTTVPNTIVVSWTAEIGRTYSMAVYLVKQLSSTVLLQRLRAKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLLCPLGKMRLTIPCRALTCSHLQCFDATLYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILKYCTDCDEIQFKEDGSWAPMRSKKEVQEVTASYNGVDGCLSSTLEHQVASHNQSSNKNKKVEVIDLTIDSSSDEEEEEPPAKRTCPSLSPTSPLSNKGILSLPHQASPVSRTPSLPAVDTSYINTSLIQDYRHPFHMTPMPYDLQGLDFFPFLSGDNQHYNTSLLAAAAAAVSDDQDLLHSSRFFPYTSSQMFLDQLSAGGSTSLPATNGSSSGSNSSLVSSNSLRESHGHGVASRSSADTASIFGIIPDIISLD

Target ORF information:

RefSeq Version	NM_019663.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus protein inhibitor of activated STAT 1 (Pias1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_019663.3

ORF Insert Sequence:

ATGGCGGACA GTGCGGAACT AAAGCAAATG GTTATGAGCC TTAGAGTTTC TGAACTCCAA 
GTACTGTTGG GCTACGCTGG GAGGAACAAG CACGGACGCA AACACGAACT TCTTACAAAA 
GCCCTGCATT TGTTAAAGGC TGGCTGTAGT CCTGCTGTAC AAATGAAAAT TAAAGAACTC 
TACAGGAGGC GGTTCCCTCA GAAAATTATG ACGCCTGCGG ACTTGTCTAT CCCCAACGTA 
CATTCAAGTC CTATGCCTCC GACTCTTTCT CCATCCACCA TTCCACAGCT CACTTATGAT 
GGCCACCCTG CATCATCCCC ACTACTCCCT GTTTCTCTTC TGGGACCCAA ACATGAACTG 
GAACTCCCAC ATCTCACGTC AGCGCTGCAC CCAGTCCACC CGGACATAAA GCTGCAGAAG 
CTACCATTCT ATGACCTGTT GGATGAACTG ATCAAGCCCA CCAGTCTAGC TTCAGACAAC 
AGCCAGCGCT TTCGGGAAAC CTGTTTTGCA TTTGCCTTGA CACCACAACA GGTGCAGCAG 
ATCAGCAGCT CCATGGATAT TTCTGGGACC AAATGTGACT TCACAGTGCA GGTCCAATTA 
AGGTTTTGTT TATCAGAAAC CAGTTGTCCA CAAGAAGATC ACTTCCCACC CAACCTTTGT 
GTAAAAGTGA ATACAAAACC TTGCAGCCTT CCAGGTTACC TTCCACCTAC TAAAAACGGT 
GTGGAACCAA AGCGACCTAG CCGACCAATT AATATCACCT CACTTGTCCG ATTGTCCACG 
ACAGTACCAA ATACCATTGT TGTTTCTTGG ACTGCAGAAA TTGGAAGAAC CTATTCCATG 
GCAGTATATC TTGTAAAACA GTTGTCCTCA ACAGTTCTTC TTCAGAGGTT ACGAGCAAAG 
GGAATAAGGA ATCCGGATCA TTCTAGAGCT TTAATTAAAG AGAAGTTAAC TGCAGATCCA 
GATAGTGAGA TAGCTACTAC CAGCCTACGG GTTTCGCTGC TGTGTCCACT TGGGAAAATG 
CGACTGACAA TCCCCTGTCG GGCACTTACC TGCTCCCACC TTCAGTGTTT TGATGCAACT 
CTTTACATTC AAATGAATGA GAAAAAACCA ACATGGGTTT GTCCTGTCTG TGATAAGAAG 
GCCCCATATG AACACCTTAT TATTGACGGG TTGTTTATGG AAATTCTAAA GTACTGCACA 
GACTGTGACG AGATACAGTT TAAGGAGGAT GGCTCGTGGG CTCCAATGAG GTCAAAGAAG 
GAGGTTCAAG AAGTCACTGC CTCCTACAAT GGAGTTGATG GTTGCTTGAG CTCCACATTG 
GAGCATCAGG TAGCGTCCCA CAACCAGTCC TCAAATAAAA ACAAGAAAGT CGAGGTCATT 
GACCTAACCA TTGACAGCTC GTCAGATGAA GAGGAGGAAG AACCCCCTGC CAAGAGGACC 
TGTCCTTCCC TGTCTCCTAC GTCACCACTA AGTAATAAAG GCATTTTAAG TCTTCCTCAT 
CAAGCCTCGC CTGTGTCCCG CACCCCAAGC CTTCCTGCTG TAGATACAAG CTACATCAAC 
ACCTCCCTCA TCCAGGACTA CAGGCACCCC TTCCACATGA CGCCTATGCC TTATGACTTA 
CAAGGATTAG ATTTCTTTCC TTTCTTATCA GGAGACAATC AGCATTACAA CACCTCCCTG 
CTAGCCGCAG CTGCAGCGGC GGTCTCAGAT GACCAGGACC TCCTGCACTC CTCCCGGTTT 
TTCCCGTATA CCTCCTCGCA GATGTTTCTC GACCAGCTAA GTGCAGGAGG GAGCACATCT 
CTGCCAGCCA CCAACGGAAG CAGTAGCGGC AGCAACAGCA GCCTTGTGTC TTCCAACAGT 
CTGAGAGAGA GCCATGGCCA TGGTGTGGCC AGCAGGAGCA GCGCAGACAC AGCGTCCATC 
TTTGGCATCA TACCAGACAT TATCTCATTG GACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Foxp1 regulation of neonatal vocalizations via cortical development.
Genes & development31(20)2039-2055(2017 Oct)
Usui N,Araujo DJ,Kulkarni A,Co M,Ellegood J,Harper M,Toriumi K,Lerch JP,Konopka G

Pias1 is essential for erythroid and vascular development in the mouse embryo.
Developmental biology415(1)98-110(2016 07)
Constanzo JD,Deng M,Rindhe S,Tang KJ,Zhang CC,Scaglioni PP

PIAS1 Promotes Lymphomagenesis through MYC Upregulation.
Cell reports15(10)2266-2278(2016 06)
Rabellino A,Melegari M,Tompkins VS,Chen W,Van Ness BG,Teruya-Feldstein J,Conacci-Sorrell M,Janz S,Scaglioni PP

PIAS1 Regulates Mutant Huntingtin Accumulation and Huntington's Disease-Associated Phenotypes In?Vivo.
Neuron90(3)507-20(2016 05)
Ochaba J,Monteys AM,O'Rourke JG,Reidling JC,Steffan JS,Davidson BL,Thompson LM

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Pias1 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

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