Cpxm1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cpxm1
Entrez Gene ID	56264
Full Name	carboxypeptidase X 1 (M14 family)
Synonyms	AA986902,Cpx-1,Cpx1,Cpxm
General protein information	Preferred Names carboxypeptidase X 1 (M14 family) Names probable carboxypeptidase X1 carboxypeptidase X (M14 family) metallocarboxypeptidase 1 metallocarboxypeptidase CPX-1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 2 Map Location: 2\|2 F1

mRNA and Protein(s)

mRNA	Protein	Name
NM_019696.2	NP_062670.2	probable carboxypeptidase X1 precursor

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	CPXM1	XP_525247.2
Rattus norvegicus (Norway rat)	Cpxm1	NP_001099981.1
Xenopus tropicalis (tropical clawed frog)	cpxm1	XP_002936314.1
Homo sapiens (human)	CPXM1	NP_062555.1
	CPXM1	XP_001114351.1
Canis lupus familiaris (dog)	CPXM1	XP_542926.2
Mus musculus (house mouse)	Cpxm1	NP_062670.2
Bos taurus (cattle)	CPXM1	NP_001015642.2
Danio rerio (zebrafish)	si:dkey-19p15.7	XP_693256.4

Gene Ontology
Bibliography

Related articles in PubMed

Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development.
Rutledge EA, Benazet JD, McMahon AP
Development (Cambridge, England)144(17)3177-3188(2017 09)

Identification of carboxypeptidase X (CPX)-1 as a positive regulator of adipogenesis.
Kim YH, Barclay JL, He J, Luo X, O'Neill HM, Keshvari S, Webster JA, Ng C, Hutley LJ, Prins JB, Whitehead JP
FASEB journal : official publication of the Federation of American Societies for Experimental Biology30(7)2528-40(2016 07)

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.
Abonnenc M, Nabeebaccus AA, Mayr U, Barallobre-Barreiro J, Dong X, Cuello F, Sur S, Drozdov I, Langley SR, Lu R, Stathopoulou K, Didangelos A, Yin X, Zimmermann WH, Shah AM, Zampetaki A, Mayr M
Circulation research113(10)1138-47(2013 Oct)

Elucidation of CPX-1 involvement in RANKL-induced osteoclastogenesis by a proteomics approach.
Chang EJ, Kwak HB, Kim H, Park JC, Lee ZH, Kim HH
FEBS letters564(1-2)166-70(2004 Apr)

Identification of mouse CPX-1, a novel member of the metallocarboxypeptidase gene family with highest similarity to CPX-2.
Lei Y, Xin X, Morgan D, Pintar JE, Fricker LD
DNA and cell biology18(2)175-85(1999 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These findings establish CPX-1 as a positive regulator of adipogenesis situated downstream of FGF-1/BAMBI that may contribute to hyperplastic adipose tissue expansion via affecting extracellular matrix remodeling.
Title: Identification of carboxypeptidase X (CPX)-1 as a positive regulator of adipogenesis.

transient up-regulation pattern of CPX-1 expression may be important for the successful progression from pre-osteoclasts to mature osteoclasts.
Title: Elucidation of CPX-1 involvement in RANKL-induced osteoclastogenesis by a proteomics approach.

The following Cpxm1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cpxm1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu11258	NM_019696.2 Latest version!	Mus musculus carboxypeptidase X 1 (M14 family) (Cpxm1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$426.30 $609.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cpxm1 ( NM_019696.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_062670.2 Mus musculus carboxypeptidase X 1 (M14 family) (Cpxm1), mRNA.

Price & Availability↑

CloneID	OMu11258
Clone ID Related Accession (Same CDS sequence)	NM_019696.2
Accession Version	NM_019696.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2169bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-20
Organism	Mus musculus(house mouse)
Product	probable carboxypeptidase X1 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY282671.1, AF077738.1 and AK132611.1. On Apr 29, 2009 this sequence version replaced NM_019696.1. ##Evidence-Data-START## Transcript exon combination :: AF077738.1, SRR1660817.78347.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTGGGGTC TCTTGCTCGC AGTGACCGCC TTTGCGCCTT CCGTCGGTCT GGGGCTGGGG 
GCTCCCAGCG CCTCAGTGCC GGGCCTGGCG CCGGGCTCAA CCCTGGCTCC ACACAGCAGC 
GTTGCACAGC CGTCCACAAA GGCAAATGAG ACCTCAGAAC GGCATGTCCG GCTTCGAGTC 
ATCAAGAAAA AAAAGATCGT TGTCAAGAAG CGAAAGAAGC TAAGGCACCC TGGTCCCTTG 
GGGACTGCTA GGCCTGTGGT GCCCACTCAC CCAGCAAAGA CCCTCACTCT CCCTGAGAAA 
CAAGAACCAG GATGTCCCCC TCTAGGCTTG GAGTCCTTGA GGGTTTCAGA TAGCCAGCTG 
GAGGCCTCCA GCAGCCAGTC CTTTGGTCTT GGAGCACACC GAGGACGGCT CAATATCCAG 
TCAGGTCTGG AGGACGGTGA CCTGTATGAT GGCGCTTGGT GCGCTGAGCA ACAAGACACT 
GAACCTTGGC TTCAGGTGGA TGCAAAGAAT CCCGTCCGCT TCGCAGGAAT TGTTACACAG 
GGCAGAAACT CTGTGTGGAG GTATGACTGG GTCACATCAT TCAAGGTCCA GTTCAGCAAT 
GACAGCCAGA CCTGGTGGAA GAGTAGGAAC AGTACTGGAA TGGACATAGT ATTTCCTGCC 
AATTCAGACG CAGAGACCCC AGTGTTGAAC CTTCTGCCAG AGCCTCAGGT GGCTCGATTC 
ATTCGCCTGC TGCCTCAGAC CTGGTTTCAG GGAGGTGCAC CTTGCCTCCG GGCAGAGATC 
CTGGCCTGCC CAGTCTCAGA TCCTAATGAC CTGTTCCCTG AGGCCCACAC ACTGGGATCT 
TCGAACTCTT TGGACTTCCG GCATCACAAT TATAAAGCTA TGAGAAAGCT GATGAAACAG 
GTGAATGAGC AGTGCCCCAA CATCACGCGC ATCTACAGCA TCGGGAAGAG CCACCAGGGT 
TTGAAGCTGT ATGTGATGGA AATGTCAGAC CATCCTGGGG AGCATGAGCT GGGCGAGCCC 
GAGGTCCGCT ACGTGGCTGG AATGCATGGG AATGAGGCCC TGGGGCGGGA GTTGCTTCTG 
CTTTTGATGC AGTTCTTATG CCATGAGTTC CTGCGAGGGG ACCCGAGAGT GACTCGGCTG 
CTCACTGAGA CACGAATCCA TCTATTGCCC TCCATGAATC CTGATGGCTA TGAGACTGCC 
TACCACAGGG GCTCAGAGCT GGTGGGCTGG GCAGAGGGCC GCTGGACCCA CCAGGGCATT 
GACCTTAACC ACAATTTTGC TGACCTCAAC ACACAACTGT GGTATGCAGA GGATGATGGA 
CTGGTACCCG ACACTGTCCC CAACCATCAC CTGCCACTGC CTACCTACTA TACATTGCCC 
AATGCCACCG TGGCTCCTGA AACGTGGGCA GTGATCAAAT GGATGAAGCG CATCCCGTTT 
GTGCTGAGTG CCAACCTCCA TGGGGGCGAG CTTGTGGTGT CCTATCCTTT CGACATGACT 
CGGACTCCGT GGGCTGCTCG TGAACTCACT CCCACACCAG ATGATGCTGT CTTCCGCTGG 
CTCAGCACTG TCTATGCTGG CACGAATAGG GCCATGCAGG ATACCGACCG CCGACCTTGT 
CATAGCCAGG ACTTCTCCTT GCATGGCAAC GTCATCAATG GAGCCGACTG GCACACAGTT 
CCTGGGAGCA TGAACGACTT CAGCTACCTA CACACCAATT GCTTTGAGGT CACAGTGGAG 
CTGTCCTGTG ACAAGTTCCC TCATGAGAAG GAGCTGCCTC AGGAGTGGGA AAACAACAAA 
GATGCTCTTC TCACCTACCT GGAGCAGGTG CGCATGGGCA TTACTGGAGT TGTCCGGGAT 
AAAGACACAG AGCTCGGCAT TGCGGATGCT GTCATTGCCG TGGAGGGCAT TAACCACGAT 
GTTACAACAG CTTGGGGCGG AGATTACTGG CGGCTGCTGA CACCTGGGGA CTATGTGGTG 
ACAGCCAGTG CTGAGGGTTA CCATACAGTC AGACAACACT GTCAGGTCAC CTTTGAAGAG 
GGCCCTGTTC CCTGCAATTT CCTACTCACC AAGACTCCCA AAGAGAGGCT TCGAGAACTG 
TTGGCAACAC GAGGGAAGTT GCCCCCAGAC CTTCGGAGGA AGCTGGAGCG GCTGAGGGGA 
CAGAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_062670.2
CDS	124..2292
Translation	MWGLLLAVTAFAPSVGLGLGAPSASVPGLAPGSTLAPHSSVAQPSTKANETSERHVRLRVIKKKKIVVKKRKKLRHPGPLGTARPVVPTHPAKTLTLPEKQEPGCPPLGLESLRVSDSQLEASSSQSFGLGAHRGRLNIQSGLEDGDLYDGAWCAEQQDTEPWLQVDAKNPVRFAGIVTQGRNSVWRYDWVTSFKVQFSNDSQTWWKSRNSTGMDIVFPANSDAETPVLNLLPEPQVARFIRLLPQTWFQGGAPCLRAEILACPVSDPNDLFPEAHTLGSSNSLDFRHHNYKAMRKLMKQVNEQCPNITRIYSIGKSHQGLKLYVMEMSDHPGEHELGEPEVRYVAGMHGNEALGRELLLLLMQFLCHEFLRGDPRVTRLLTETRIHLLPSMNPDGYETAYHRGSELVGWAEGRWTHQGIDLNHNFADLNTQLWYAEDDGLVPDTVPNHHLPLPTYYTLPNATVAPETWAVIKWMKRIPFVLSANLHGGELVVSYPFDMTRTPWAARELTPTPDDAVFRWLSTVYAGTNRAMQDTDRRPCHSQDFSLHGNVINGADWHTVPGSMNDFSYLHTNCFEVTVELSCDKFPHEKELPQEWENNKDALLTYLEQVRMGITGVVRDKDTELGIADAVIAVEGINHDVTTAWGGDYWRLLTPGDYVVTASAEGYHTVRQHCQVTFEEGPVPCNFLLTKTPKERLRELLATRGKLPPDLRRKLERLRGQK

Target ORF information:

RefSeq Version	NM_019696.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus carboxypeptidase X 1 (M14 family) (Cpxm1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_019696.2

ORF Insert Sequence:

ATGTGGGGTC TCTTGCTCGC AGTGACCGCC TTTGCGCCTT CCGTCGGTCT GGGGCTGGGG 
GCTCCCAGCG CCTCAGTGCC GGGCCTGGCG CCGGGCTCAA CCCTGGCTCC ACACAGCAGC 
GTTGCACAGC CGTCCACAAA GGCAAATGAG ACCTCAGAAC GGCATGTCCG GCTTCGAGTC 
ATCAAGAAAA AAAAGATCGT TGTCAAGAAG CGAAAGAAGC TAAGGCACCC TGGTCCCTTG 
GGGACTGCTA GGCCTGTGGT GCCCACTCAC CCAGCAAAGA CCCTCACTCT CCCTGAGAAA 
CAAGAACCAG GATGTCCCCC TCTAGGCTTG GAGTCCTTGA GGGTTTCAGA TAGCCAGCTG 
GAGGCCTCCA GCAGCCAGTC CTTTGGTCTT GGAGCACACC GAGGACGGCT CAATATCCAG 
TCAGGTCTGG AGGACGGTGA CCTGTATGAT GGCGCTTGGT GCGCTGAGCA ACAAGACACT 
GAACCTTGGC TTCAGGTGGA TGCAAAGAAT CCCGTCCGCT TCGCAGGAAT TGTTACACAG 
GGCAGAAACT CTGTGTGGAG GTATGACTGG GTCACATCAT TCAAGGTCCA GTTCAGCAAT 
GACAGCCAGA CCTGGTGGAA GAGTAGGAAC AGTACTGGAA TGGACATAGT ATTTCCTGCC 
AATTCAGACG CAGAGACCCC AGTGTTGAAC CTTCTGCCAG AGCCTCAGGT GGCTCGATTC 
ATTCGCCTGC TGCCTCAGAC CTGGTTTCAG GGAGGTGCAC CTTGCCTCCG GGCAGAGATC 
CTGGCCTGCC CAGTCTCAGA TCCTAATGAC CTGTTCCCTG AGGCCCACAC ACTGGGATCT 
TCGAACTCTT TGGACTTCCG GCATCACAAT TATAAAGCTA TGAGAAAGCT GATGAAACAG 
GTGAATGAGC AGTGCCCCAA CATCACGCGC ATCTACAGCA TCGGGAAGAG CCACCAGGGT 
TTGAAGCTGT ATGTGATGGA AATGTCAGAC CATCCTGGGG AGCATGAGCT GGGCGAGCCC 
GAGGTCCGCT ACGTGGCTGG AATGCATGGG AATGAGGCCC TGGGGCGGGA GTTGCTTCTG 
CTTTTGATGC AGTTCTTATG CCATGAGTTC CTGCGAGGGG ACCCGAGAGT GACTCGGCTG 
CTCACTGAGA CACGAATCCA TCTATTGCCC TCCATGAATC CTGATGGCTA TGAGACTGCC 
TACCACAGGG GCTCAGAGCT GGTGGGCTGG GCAGAGGGCC GCTGGACCCA CCAGGGCATT 
GACCTTAACC ACAATTTTGC TGACCTCAAC ACACAACTGT GGTATGCAGA GGATGATGGA 
CTGGTACCCG ACACTGTCCC CAACCATCAC CTGCCACTGC CTACCTACTA TACATTGCCC 
AATGCCACCG TGGCTCCTGA AACGTGGGCA GTGATCAAAT GGATGAAGCG CATCCCGTTT 
GTGCTGAGTG CCAACCTCCA TGGGGGCGAG CTTGTGGTGT CCTATCCTTT CGACATGACT 
CGGACTCCGT GGGCTGCTCG TGAACTCACT CCCACACCAG ATGATGCTGT CTTCCGCTGG 
CTCAGCACTG TCTATGCTGG CACGAATAGG GCCATGCAGG ATACCGACCG CCGACCTTGT 
CATAGCCAGG ACTTCTCCTT GCATGGCAAC GTCATCAATG GAGCCGACTG GCACACAGTT 
CCTGGGAGCA TGAACGACTT CAGCTACCTA CACACCAATT GCTTTGAGGT CACAGTGGAG 
CTGTCCTGTG ACAAGTTCCC TCATGAGAAG GAGCTGCCTC AGGAGTGGGA AAACAACAAA 
GATGCTCTTC TCACCTACCT GGAGCAGGTG CGCATGGGCA TTACTGGAGT TGTCCGGGAT 
AAAGACACAG AGCTCGGCAT TGCGGATGCT GTCATTGCCG TGGAGGGCAT TAACCACGAT 
GTTACAACAG CTTGGGGCGG AGATTACTGG CGGCTGCTGA CACCTGGGGA CTATGTGGTG 
ACAGCCAGTG CTGAGGGTTA CCATACAGTC AGACAACACT GTCAGGTCAC CTTTGAAGAG 
GGCCCTGTTC CCTGCAATTT CCTACTCACC AAGACTCCCA AAGAGAGGCT TCGAGAACTG 
TTGGCAACAC GAGGGAAGTT GCCCCCAGAC CTTCGGAGGA AGCTGGAGCG GCTGAGGGGA 
CAGAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development.
Development (Cambridge, England)144(17)3177-3188(2017 09)
Rutledge EA,Benazet JD,McMahon AP

Identification of carboxypeptidase X (CPX)-1 as a positive regulator of adipogenesis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology30(7)2528-40(2016 07)
Kim YH,Barclay JL,He J,Luo X,O'Neill HM,Keshvari S,Webster JA,Ng C,Hutley LJ,Prins JB,Whitehead JP

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.
Circulation research113(10)1138-47(2013 Oct)
Abonnenc M,Nabeebaccus AA,Mayr U,Barallobre-Barreiro J,Dong X,Cuello F,Sur S,Drozdov I,Langley SR,Lu R,Stathopoulou K,Didangelos A,Yin X,Zimmermann WH,Shah AM,Zampetaki A,Mayr M

Elucidation of CPX-1 involvement in RANKL-induced osteoclastogenesis by a proteomics approach.
FEBS letters564(1-2)166-70(2004 Apr)
Chang EJ,Kwak HB,Kim H,Park JC,Lee ZH,Kim HH

Identification of mouse CPX-1, a novel member of the metallocarboxypeptidase gene family with highest similarity to CPX-2.
DNA and cell biology18(2)175-85(1999 Feb)
Lei Y,Xin X,Morgan D,Pintar JE,Fricker LD