Stx8 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Stx8
Entrez Gene ID	55943
Full Name	syntaxin 8
Synonyms	0610007H08Rik,1110002H11Rik,4930571E13Rik,CARB
General protein information	Preferred Names syntaxin 8 Names syntaxin-8 syntaxin-like protein 3I35
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 11 Map Location: 11\|11 B3

mRNA and Protein(s)

mRNA	Protein	Name
XM_011249133.1	XP_011247435.1	syntaxin-8 isoform X1
NM_001361350.1	NP_001348279.1	syntaxin-8 isoform 3
NM_001361352.1	NP_001348281.1	syntaxin-8 isoform 4
NM_001356314.1	NP_001343243.1	syntaxin-8 isoform 2
NM_018768.3	NP_061238.1	syntaxin-8 isoform 1
NM_018768.2	NP_061238.1	syntaxin-8 isoform 1
NM_001361351.1	NP_001348280.1	syntaxin-8 isoform 3
XM_030246161.1	XP_030102021.1	syntaxin-8 isoform X1

Pathways from BioSystems

Homologies

Bos taurus (cattle)	STX8	NP_001071505.1
Gallus gallus (chicken)	STX8	NP_001025869.1
Drosophila melanogaster (fruit fly)	Syx8	NP_524113.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP006100	XP_316159.4
Homo sapiens (human)	STX8	NP_004844.1
Pan troglodytes (chimpanzee)	STX8	XP_001165656.1
Mus musculus (house mouse)	Stx8	NP_061238.1
Rattus norvegicus (Norway rat)	Stx8	NP_113844.1
	STX8	XP_001113412.1
Xenopus tropicalis (tropical clawed frog)	stx8	NP_001032338.1
Canis lupus familiaris (dog)	STX8	XP_005620378.1
Danio rerio (zebrafish)	stx8	NP_956669.1

Gene Ontology
Bibliography

Related articles in PubMed

Syntaxin 8 regulates platelet dense granule secretion, aggregation, and thrombus stability.
Golebiewska EM, Harper MT, Williams CM, Savage JS, Goggs R, Fischer von Mollard G, Poole AW
The Journal of biological chemistry290(3)1536-45(2015 Jan)

Histopathology reveals correlative and unique phenotypes in a high-throughput mouse phenotyping screen.
Adissu HA, Estabel J, Sunter D, Tuck E, Hooks Y, Carragher DM, Clarke K, Karp NA, , Newbigging S, Jones N, Morikawa L, White JK, McKerlie C
Disease models & mechanisms7(5)515-24(2014 May)

UVRAG is required for virus entry through combinatorial interaction with the class C-Vps complex and SNAREs.
Pirooz SD, He S, Zhang T, Zhang X, Zhao Z, Oh S, O'Connell D, Khalilzadeh P, Amini-Bavil-Olyaee S, Farzan M, Liang C
Proceedings of the National Academy of Sciences of the United States of America111(7)2716-21(2014 Feb)

Interaction between syntaxin 8 and HECTd3, a HECT domain ligase.
Zhang L, Kang L, Bond W, Zhang N
Cellular and molecular neurobiology29(1)115-21(2009 Feb)

The phagosomal proteome in interferon-gamma-activated macrophages.
Trost M, English L, Lemieux S, Courcelles M, Desjardins M, Thibault P
Immunity30(1)143-54(2009 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Syntaxin 8 has a role in regulating platelet dense granule secretion, aggregation, and thrombus stability
Title: Syntaxin 8 regulates platelet dense granule secretion, aggregation, and thrombus stability.

Syntaxin 8 and HECTd3 have similar subcellular localization.
Title: Interaction between syntaxin 8 and HECTd3, a HECT domain ligase.

The following Stx8 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Stx8 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu19226	NM_018768.3 Latest version!	Mus musculus syntaxin 8 (Stx8), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00
OMu83719	NM_001356314.1 Latest version!	Mus musculus syntaxin 8 (Stx8), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OMu69574	XM_011249133.1 Latest version!	Mus musculus syntaxin 8 (Stx8), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OMu83993	NM_001361350.1 Latest version!	Mus musculus syntaxin 8 (Stx8), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OMu83993	NM_001361351.1 Latest version!	Mus musculus syntaxin 8 (Stx8), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OMu83997	NM_001361352.1 Latest version!	Mus musculus syntaxin 8 (Stx8), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OMu85846	XM_030246161.1 Latest version!	Mus musculus syntaxin 8 (Stx8), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
View Old Accession Versions >>
OMu19226	NM_018768.2	Mus musculus syntaxin 8 (Stx8), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Stx8 ( NM_018768.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_061238.1 Mus musculus syntaxin 8 (Stx8), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu19226
Clone ID Related Accession (Same CDS sequence)	NM_018768.3 , NM_018768.2
Accession Version	NM_018768.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 711bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-22
Organism	Mus musculus(house mouse)
Product	syntaxin-8 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK003297.1 and BC048167.1. On Mar 19, 2018 this sequence version replaced NM_018768.2. ##Evidence-Data-START## Transcript exon combination :: BC048167.1, AK003297.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849377 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCCCGG ACCCCTGGTT CTCCACATAC GATTCTACGT GTCAGATAGC CCAAGAAATC 
GCTGAGAAGA TTCAAGAACG AAATCAGTGT GAAAGAAGAG GTGAAAAGAC ACCGAAGCTT 
ACCTTGACAA TCAGAACGTT GTTGAAGAAT CTGAAGGTAA AGATCGACCT TTTGAAGGAC 
TTACTGCTAA GAGCTGTGTC GACACGCCAG ATAACACAAC TGGAGGGGGA TCGAAGACAG 
AACCTGCTGG ATGACCTTGT CACCCGAGAG AGACTGCTCC TGGCATCGTT TAAGAATGAG 
GGTGCAGAGC CGGATCTGAT CAGGTCCAGC CTGATGAGCG AAGAAGCAAA GCGAGGAACT 
CCCAACCCTT GGCTCTGTGA GGAGCCGGAG GAGACCAGAG GTTTGGGTTT TGATGAGATC 
CGACAACAGC AGCAGAAAAT TATTCAAGAA CAGGACGCGG GTCTTGATGC CCTTTCCTCT 
ATCATAAGTC GCCAAAAACA AATGGGCCAG GAAATTGGGA ACGAACTGGA TGAACAGAAT 
GAGATCATCG ATGACCTTGC CAACCTCGTT GAGAACACAG ATGAGAAGCT TCGAACTGAA 
GCCAGGCGAG TGACCCTGGT GGACAGAAAG TCAACTTCCT GTGGGATGAT CATGGTGATT 
TTATTGCTGC TCGTGGCTAT TGTGGTCGTT GCAGTGTGGC CAACCAACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_061238.1
CDS	44..754
Translation	MAPDPWFSTYDSTCQIAQEIAEKIQERNQCERRGEKTPKLTLTIRTLLKNLKVKIDLLKDLLLRAVSTRQITQLEGDRRQNLLDDLVTRERLLLASFKNEGAEPDLIRSSLMSEEAKRGTPNPWLCEEPEETRGLGFDEIRQQQQKIIQEQDAGLDALSSIISRQKQMGQEIGNELDEQNEIIDDLANLVENTDEKLRTEARRVTLVDRKSTSCGMIMVILLLLVAIVVVAVWPTN

Target ORF information:

RefSeq Version	NM_018768.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus syntaxin 8 (Stx8), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_018768.3

ORF Insert Sequence:

ATGGCCCCGG ACCCCTGGTT CTCCACATAC GATTCTACGT GTCAGATAGC CCAAGAAATC 
GCTGAGAAGA TTCAAGAACG AAATCAGTGT GAAAGAAGAG GTGAAAAGAC ACCGAAGCTT 
ACCTTGACAA TCAGAACGTT GTTGAAGAAT CTGAAGGTAA AGATCGACCT TTTGAAGGAC 
TTACTGCTAA GAGCTGTGTC GACACGCCAG ATAACACAAC TGGAGGGGGA TCGAAGACAG 
AACCTGCTGG ATGACCTTGT CACCCGAGAG AGACTGCTCC TGGCATCGTT TAAGAATGAG 
GGTGCAGAGC CGGATCTGAT CAGGTCCAGC CTGATGAGCG AAGAAGCAAA GCGAGGAACT 
CCCAACCCTT GGCTCTGTGA GGAGCCGGAG GAGACCAGAG GTTTGGGTTT TGATGAGATC 
CGACAACAGC AGCAGAAAAT TATTCAAGAA CAGGACGCGG GTCTTGATGC CCTTTCCTCT 
ATCATAAGTC GCCAAAAACA AATGGGCCAG GAAATTGGGA ACGAACTGGA TGAACAGAAT 
GAGATCATCG ATGACCTTGC CAACCTCGTT GAGAACACAG ATGAGAAGCT TCGAACTGAA 
GCCAGGCGAG TGACCCTGGT GGACAGAAAG TCAACTTCCT GTGGGATGAT CATGGTGATT 
TTATTGCTGC TCGTGGCTAT TGTGGTCGTT GCAGTGTGGC CAACCAACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Stx8 ( NM_018768.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_061238.1 Mus musculus syntaxin 8 (Stx8), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu19226
Clone ID Related Accession (Same CDS sequence)	NM_018768.3 , NM_018768.2
Accession Version	NM_018768.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 711bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-11-18
Organism	Mus musculus(house mouse)
Product	syntaxin-8 isoform 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC048167.1. On or before Dec 7, 2005 this sequence version replaced XM_924682.1, XM_917120.1, XM_924689.1, XM_924696.1, XM_924704.1, XM_924708.1, XM_924711.1, XM_924713.1, NM_018768.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). ##Evidence-Data-START## Transcript exon combination :: BC048167.1, BC038186.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849377 [ECO:0000348] ##Evidence-Data-END##

ATGGCCCCGG ACCCCTGGTT CTCCACATAC GATTCTACGT GTCAGATAGC CCAAGAAATC 
GCTGAGAAGA TTCAAGAACG AAATCAGTGT GAAAGAAGAG GTGAAAAGAC ACCGAAGCTT 
ACCTTGACAA TCAGAACGTT GTTGAAGAAT CTGAAGGTAA AGATCGACCT TTTGAAGGAC 
TTACTGCTAA GAGCTGTGTC GACACGCCAG ATAACACAAC TGGAGGGGGA TCGAAGACAG 
AACCTGCTGG ATGACCTTGT CACCCGAGAG AGACTGCTCC TGGCATCGTT TAAGAATGAG 
GGTGCAGAGC CGGATCTGAT CAGGTCCAGC CTGATGAGCG AAGAAGCAAA GCGAGGAACT 
CCCAACCCTT GGCTCTGTGA GGAGCCGGAG GAGACCAGAG GTTTGGGTTT TGATGAGATC 
CGACAACAGC AGCAGAAAAT TATTCAAGAA CAGGACGCGG GTCTTGATGC CCTTTCCTCT 
ATCATAAGTC GCCAAAAACA AATGGGCCAG GAAATTGGGA ACGAACTGGA TGAACAGAAT 
GAGATCATCG ATGACCTTGC CAACCTCGTT GAGAACACAG ATGAGAAGCT TCGAACTGAA 
GCCAGGCGAG TGACCCTGGT GGACAGAAAG TCAACTTCCT GTGGGATGAT CATGGTGATT 
TTATTGCTGC TCGTGGCTAT TGTGGTCGTT GCAGTGTGGC CAACCAACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_061238.1
CDS	19..729
Translation	MAPDPWFSTYDSTCQIAQEIAEKIQERNQCERRGEKTPKLTLTIRTLLKNLKVKIDLLKDLLLRAVSTRQITQLEGDRRQNLLDDLVTRERLLLASFKNEGAEPDLIRSSLMSEEAKRGTPNPWLCEEPEETRGLGFDEIRQQQQKIIQEQDAGLDALSSIISRQKQMGQEIGNELDEQNEIIDDLANLVENTDEKLRTEARRVTLVDRKSTSCGMIMVILLLLVAIVVVAVWPTN

Target ORF information:

RefSeq Version	NM_018768.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus syntaxin 8 (Stx8), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_018768.2

ORF Insert Sequence:

ATGGCCCCGG ACCCCTGGTT CTCCACATAC GATTCTACGT GTCAGATAGC CCAAGAAATC 
GCTGAGAAGA TTCAAGAACG AAATCAGTGT GAAAGAAGAG GTGAAAAGAC ACCGAAGCTT 
ACCTTGACAA TCAGAACGTT GTTGAAGAAT CTGAAGGTAA AGATCGACCT TTTGAAGGAC 
TTACTGCTAA GAGCTGTGTC GACACGCCAG ATAACACAAC TGGAGGGGGA TCGAAGACAG 
AACCTGCTGG ATGACCTTGT CACCCGAGAG AGACTGCTCC TGGCATCGTT TAAGAATGAG 
GGTGCAGAGC CGGATCTGAT CAGGTCCAGC CTGATGAGCG AAGAAGCAAA GCGAGGAACT 
CCCAACCCTT GGCTCTGTGA GGAGCCGGAG GAGACCAGAG GTTTGGGTTT TGATGAGATC 
CGACAACAGC AGCAGAAAAT TATTCAAGAA CAGGACGCGG GTCTTGATGC CCTTTCCTCT 
ATCATAAGTC GCCAAAAACA AATGGGCCAG GAAATTGGGA ACGAACTGGA TGAACAGAAT 
GAGATCATCG ATGACCTTGC CAACCTCGTT GAGAACACAG ATGAGAAGCT TCGAACTGAA 
GCCAGGCGAG TGACCCTGGT GGACAGAAAG TCAACTTCCT GTGGGATGAT CATGGTGATT 
TTATTGCTGC TCGTGGCTAT TGTGGTCGTT GCAGTGTGGC CAACCAACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Stx8 ( NM_001356314.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001343243.1 Mus musculus syntaxin 8 (Stx8), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu83719
Clone ID Related Accession (Same CDS sequence)	NM_001356314.1
Accession Version	NM_001356314.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 393bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-24
Organism	Mus musculus(house mouse)
Product	syntaxin-8 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK003297.1, AK011376.1 and AL663076.17. On Sep 29, 2017 this sequence version replaced XM_011249133.1. Transcript Variant: This variant (2) lacks several exons and includes an alternate 3' terminal exon, compared to variant 1. It encodes isoform 2, which is shorter and has a novel C-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: BC061118.1, AK016271.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849377 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCCCGG ACCCCTGGTT CTCCACATAC GATTCTACGT GTCAGATAGC CCAAGAAATC 
GCTGAGAAGA TTCAAGAACG AAATCAGTGT GAAAGAAGAG GTGAAAAGAC ACCGAAGCTT 
ACCTTGACAA TCAGAACGTT GTTGAAGAAT CTGAAGGTAA AGATCGACCT TTTGAAGGAC 
TTACTGCTAA GAGCTGTGTC GACACGCCAG ATAACACAAC TGGAGGGGGA TCGAAGACAG 
AACCTGCTGG ATGACCTTGT CACCCGAGAG AGACTGCTCC TGGCATCGTT TAAGAATGAG 
GGTGCAGAGC CGGATCTGAT CAGTCTCGGC ATCTCTGTGT CCCTGTATCT CTCACCAGTT 
CCAGCTGAGC ATCAGTGGCA GCACCTCGGT TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001343243.1
CDS	44..436
Translation	MAPDPWFSTYDSTCQIAQEIAEKIQERNQCERRGEKTPKLTLTIRTLLKNLKVKIDLLKDLLLRAVSTRQITQLEGDRRQNLLDDLVTRERLLLASFKNEGAEPDLISLGISVSLYLSPVPAEHQWQHLG

Target ORF information:

RefSeq Version	NM_001356314.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus syntaxin 8 (Stx8), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001356314.1

ORF Insert Sequence:

ATGGCCCCGG ACCCCTGGTT CTCCACATAC GATTCTACGT GTCAGATAGC CCAAGAAATC 
GCTGAGAAGA TTCAAGAACG AAATCAGTGT GAAAGAAGAG GTGAAAAGAC ACCGAAGCTT 
ACCTTGACAA TCAGAACGTT GTTGAAGAAT CTGAAGGTAA AGATCGACCT TTTGAAGGAC 
TTACTGCTAA GAGCTGTGTC GACACGCCAG ATAACACAAC TGGAGGGGGA TCGAAGACAG 
AACCTGCTGG ATGACCTTGT CACCCGAGAG AGACTGCTCC TGGCATCGTT TAAGAATGAG 
GGTGCAGAGC CGGATCTGAT CAGTCTCGGC ATCTCTGTGT CCCTGTATCT CTCACCAGTT 
CCAGCTGAGC ATCAGTGGCA GCACCTCGGT TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Stx8 ( XM_011249133.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011247435.1 Mus musculus syntaxin 8 (Stx8), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu69574
Clone ID Related Accession (Same CDS sequence)	XM_011249133.1
Accession Version	XM_011249133.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 465bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(House mouse)
Product	syntaxin-8 isoform X1
Comment	MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000077.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGCCGCA CGGGCCGCCG TAGTCAGCTG CTACGAGCAG GAAGTGTCCC AGCTGCGGGC 
GGAGACTGCA CCATGGCCCC GGACCCCTGG TTCTCCACAT ACGATTCTAC GTGTCAGATA 
GCCCAAGAAA TCGCTGAGAA GATTCAAGAA CGAAATCAGT GTGAAAGAAG AGGTGAAAAG 
ACACCGAAGC TTACCTTGAC AATCAGAACG TTGTTGAAGA ATCTGAAGGT AAAGATCGAC 
CTTTTGAAGG ACTTACTGCT AAGAGCTGTG TCGACACGCC AGATAACACA ACTGGAGGGG 
GATCGAAGAC AGAACCTGCT GGATGACCTT GTCACCCGAG AGAGACTGCT CCTGGCATCG 
TTTAAGAATG AGGGTGCAGA GCCGGATCTG ATCAGTCTCG GCATCTCTGT GTCCCTGTAT 
CTCTCACCAG TTCCAGCTGA GCATCAGTGG CAGCACCTCG GTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011247435.1
CDS	19..483
Translation	MSRTGRRSQLLRAGSVPAAGGDCTMAPDPWFSTYDSTCQIAQEIAEKIQERNQCERRGEKTPKLTLTIRTLLKNLKVKIDLLKDLLLRAVSTRQITQLEGDRRQNLLDDLVTRERLLLASFKNEGAEPDLISLGISVSLYLSPVPAEHQWQHLG

Target ORF information:

RefSeq Version	XM_011249133.1
Organism	Mus musculus(House mouse)
Definition	Mus musculus syntaxin 8 (Stx8), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011249133.1

ORF Insert Sequence:

ATGAGCCGCA CGGGCCGCCG TAGTCAGCTG CTACGAGCAG GAAGTGTCCC AGCTGCGGGC 
GGAGACTGCA CCATGGCCCC GGACCCCTGG TTCTCCACAT ACGATTCTAC GTGTCAGATA 
GCCCAAGAAA TCGCTGAGAA GATTCAAGAA CGAAATCAGT GTGAAAGAAG AGGTGAAAAG 
ACACCGAAGC TTACCTTGAC AATCAGAACG TTGTTGAAGA ATCTGAAGGT AAAGATCGAC 
CTTTTGAAGG ACTTACTGCT AAGAGCTGTG TCGACACGCC AGATAACACA ACTGGAGGGG 
GATCGAAGAC AGAACCTGCT GGATGACCTT GTCACCCGAG AGAGACTGCT CCTGGCATCG 
TTTAAGAATG AGGGTGCAGA GCCGGATCTG ATCAGTCTCG GCATCTCTGT GTCCCTGTAT 
CTCTCACCAG TTCCAGCTGA GCATCAGTGG CAGCACCTCG GTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Stx8 ( NM_001361350.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001348279.1 Mus musculus syntaxin 8 (Stx8), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OMu83993
Clone ID Related Accession (Same CDS sequence)	NM_001361350.1 , NM_001361351.1
Accession Version	NM_001361350.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 378bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-22
Organism	Mus musculus(house mouse)
Product	syntaxin-8 isoform 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL663076.17 and AL669842.11. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: BU841844.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164131, SAMN01164132 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGCGAAG AAGCAAAGCG AGGAACTCCC AACCCTTGGC TCTGTGAGGA GCCGGAGGAG 
ACCAGAGGTT TGGGTTTTGA TGAGATCCGA CAACAGCAGC AGAAAATTAT TCAAGAACAG 
GACGCGGGTC TTGATGCCCT TTCCTCTATC ATAAGTCGCC AAAAACAAAT GGGCCAGGAA 
ATTGGGAACG AACTGGATGA ACAGAATGAG ATCATCGATG ACCTTGCCAA CCTCGTTGAG 
AACACAGATG AGAAGCTTCG AACTGAAGCC AGGCGAGTGA CCCTGGTGGA CAGAAAGTCA 
ACTTCCTGTG GGATGATCAT GGTGATTTTA TTGCTGCTCG TGGCTATTGT GGTCGTTGCA 
GTGTGGCCAA CCAACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001348279.1
CDS	171..548
Translation	MSEEAKRGTPNPWLCEEPEETRGLGFDEIRQQQQKIIQEQDAGLDALSSIISRQKQMGQEIGNELDEQNEIIDDLANLVENTDEKLRTEARRVTLVDRKSTSCGMIMVILLLLVAIVVVAVWPTN

Target ORF information:

RefSeq Version	NM_001361350.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus syntaxin 8 (Stx8), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001361350.1

ORF Insert Sequence:

ATGAGCGAAG AAGCAAAGCG AGGAACTCCC AACCCTTGGC TCTGTGAGGA GCCGGAGGAG 
ACCAGAGGTT TGGGTTTTGA TGAGATCCGA CAACAGCAGC AGAAAATTAT TCAAGAACAG 
GACGCGGGTC TTGATGCCCT TTCCTCTATC ATAAGTCGCC AAAAACAAAT GGGCCAGGAA 
ATTGGGAACG AACTGGATGA ACAGAATGAG ATCATCGATG ACCTTGCCAA CCTCGTTGAG 
AACACAGATG AGAAGCTTCG AACTGAAGCC AGGCGAGTGA CCCTGGTGGA CAGAAAGTCA 
ACTTCCTGTG GGATGATCAT GGTGATTTTA TTGCTGCTCG TGGCTATTGT GGTCGTTGCA 
GTGTGGCCAA CCAACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Stx8 ( NM_001361351.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001348280.1 Mus musculus syntaxin 8 (Stx8), transcript variant 4, mRNA.

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CloneID	OMu83993
Clone ID Related Accession (Same CDS sequence)	NM_001361350.1 , NM_001361351.1
Accession Version	NM_001361351.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 378bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-23
Organism	Mus musculus(house mouse)
Product	syntaxin-8 isoform 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK003297.1, AK018716.1 and BC048167.1. ##Evidence-Data-START## Transcript exon combination :: AK018716.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849380 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGCGAAG AAGCAAAGCG AGGAACTCCC AACCCTTGGC TCTGTGAGGA GCCGGAGGAG 
ACCAGAGGTT TGGGTTTTGA TGAGATCCGA CAACAGCAGC AGAAAATTAT TCAAGAACAG 
GACGCGGGTC TTGATGCCCT TTCCTCTATC ATAAGTCGCC AAAAACAAAT GGGCCAGGAA 
ATTGGGAACG AACTGGATGA ACAGAATGAG ATCATCGATG ACCTTGCCAA CCTCGTTGAG 
AACACAGATG AGAAGCTTCG AACTGAAGCC AGGCGAGTGA CCCTGGTGGA CAGAAAGTCA 
ACTTCCTGTG GGATGATCAT GGTGATTTTA TTGCTGCTCG TGGCTATTGT GGTCGTTGCA 
GTGTGGCCAA CCAACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001348280.1
CDS	210..587
Translation	MSEEAKRGTPNPWLCEEPEETRGLGFDEIRQQQQKIIQEQDAGLDALSSIISRQKQMGQEIGNELDEQNEIIDDLANLVENTDEKLRTEARRVTLVDRKSTSCGMIMVILLLLVAIVVVAVWPTN

Target ORF information:

RefSeq Version	NM_001361351.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus syntaxin 8 (Stx8), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001361351.1

ORF Insert Sequence:

ATGAGCGAAG AAGCAAAGCG AGGAACTCCC AACCCTTGGC TCTGTGAGGA GCCGGAGGAG 
ACCAGAGGTT TGGGTTTTGA TGAGATCCGA CAACAGCAGC AGAAAATTAT TCAAGAACAG 
GACGCGGGTC TTGATGCCCT TTCCTCTATC ATAAGTCGCC AAAAACAAAT GGGCCAGGAA 
ATTGGGAACG AACTGGATGA ACAGAATGAG ATCATCGATG ACCTTGCCAA CCTCGTTGAG 
AACACAGATG AGAAGCTTCG AACTGAAGCC AGGCGAGTGA CCCTGGTGGA CAGAAAGTCA 
ACTTCCTGTG GGATGATCAT GGTGATTTTA TTGCTGCTCG TGGCTATTGT GGTCGTTGCA 
GTGTGGCCAA CCAACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Stx8 ( NM_001361352.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001348281.1 Mus musculus syntaxin 8 (Stx8), transcript variant 5, mRNA.

Price & Availability↑

CloneID	OMu83997
Clone ID Related Accession (Same CDS sequence)	NM_001361352.1
Accession Version	NM_001361352.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 381bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-24
Organism	Mus musculus(house mouse)
Product	syntaxin-8 isoform 4
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK003297.1, AK035105.1, AL663076.17 and BE984450.1. ##Evidence-Data-START## Transcript exon combination :: CX206895.1, CX217722.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849377 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCCCGG ACCCCTGGTT CTCCACATAC GATTCTACGT GTCAGATAGC CCAAGAAATC 
GCTGAGAAGA TTCAAGAACG AAATCAGTGT GAAAGAAGAG GTGAAAAGAC ACCGAAGCTT 
ACCTTGACAA TCAGAACGTT GTTGAAGAAT CTGAAGGTAA AGATCGACCT TTTGAAGGAC 
TTACTGCTAA GAGCTGTGTC GACACGCCAG ATGTATCCAT GTAAACATTT CCACCTTTTC 
TGGAGTGGGA GGAAAAACAA TCTTAAGACA GGAAGGAATC TGGGCCATCC AGATTTTTCC 
ACAGCTCAAG GAGGACTTGG TTTCCACACT GTTGCTATAA TTTTACATTC TGTCTTAAGT 
GTCTGCTCAC TGTTACAGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001348281.1
CDS	44..424
Translation	MAPDPWFSTYDSTCQIAQEIAEKIQERNQCERRGEKTPKLTLTIRTLLKNLKVKIDLLKDLLLRAVSTRQMYPCKHFHLFWSGRKNNLKTGRNLGHPDFSTAQGGLGFHTVAIILHSVLSVCSLLQ

Target ORF information:

RefSeq Version	NM_001361352.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus syntaxin 8 (Stx8), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001361352.1

ORF Insert Sequence:

ATGGCCCCGG ACCCCTGGTT CTCCACATAC GATTCTACGT GTCAGATAGC CCAAGAAATC 
GCTGAGAAGA TTCAAGAACG AAATCAGTGT GAAAGAAGAG GTGAAAAGAC ACCGAAGCTT 
ACCTTGACAA TCAGAACGTT GTTGAAGAAT CTGAAGGTAA AGATCGACCT TTTGAAGGAC 
TTACTGCTAA GAGCTGTGTC GACACGCCAG ATGTATCCAT GTAAACATTT CCACCTTTTC 
TGGAGTGGGA GGAAAAACAA TCTTAAGACA GGAAGGAATC TGGGCCATCC AGATTTTTCC 
ACAGCTCAAG GAGGACTTGG TTTCCACACT GTTGCTATAA TTTTACATTC TGTCTTAAGT 
GTCTGCTCAC TGTTACAGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Stx8 ( XM_030246161.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_030102021.1 Mus musculus syntaxin 8 (Stx8), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu85846
Clone ID Related Accession (Same CDS sequence)	XM_030246161.1
Accession Version	XM_030246161.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 420bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	syntaxin-8 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000077.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGCCGCA CGGGCCGCCG TAGTCAGCTG CTACGAGCAG GAAGTGTCCC AGCTGCGGGC 
GGAGACTGCA CCATGGCCCC GGACCCCTGG TTCTCCACAT ACGATTCTAC GTGTCAGATA 
GCCCAAGAAA TCGCTGAGAA GATTCAAGAA CGAAATCAGT GTGAAAGAAG AGGTGAAAAG 
ACACCGAAGC TTACCTTGAC AATCAGAACG TTGTTGAAGA ATCTGAAGGT AAAGATCGAC 
CTTTTGAAGG ACTTACTGCT AAGAGCTGTG TCGACACGCC AGATAACACA ACTGGAGGGG 
GATCGAAGAC AGAACCTGCT GGATGACCTT GTCACCCGAG AGAGACTGCT CCTGGCATCG 
TTTAAGAATG AGGGTGCAGA GCCGGATCTG ATCAGGTCCA GCCTGATGAC CCAAGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_030102021.1
CDS	19..438
Translation	MSRTGRRSQLLRAGSVPAAGGDCTMAPDPWFSTYDSTCQIAQEIAEKIQERNQCERRGEKTPKLTLTIRTLLKNLKVKIDLLKDLLLRAVSTRQITQLEGDRRQNLLDDLVTRERLLLASFKNEGAEPDLIRSSLMTQD

Target ORF information:

RefSeq Version	XM_030246161.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus syntaxin 8 (Stx8), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_030246161.1

ORF Insert Sequence:

ATGAGCCGCA CGGGCCGCCG TAGTCAGCTG CTACGAGCAG GAAGTGTCCC AGCTGCGGGC 
GGAGACTGCA CCATGGCCCC GGACCCCTGG TTCTCCACAT ACGATTCTAC GTGTCAGATA 
GCCCAAGAAA TCGCTGAGAA GATTCAAGAA CGAAATCAGT GTGAAAGAAG AGGTGAAAAG 
ACACCGAAGC TTACCTTGAC AATCAGAACG TTGTTGAAGA ATCTGAAGGT AAAGATCGAC 
CTTTTGAAGG ACTTACTGCT AAGAGCTGTG TCGACACGCC AGATAACACA ACTGGAGGGG 
GATCGAAGAC AGAACCTGCT GGATGACCTT GTCACCCGAG AGAGACTGCT CCTGGCATCG 
TTTAAGAATG AGGGTGCAGA GCCGGATCTG ATCAGGTCCA GCCTGATGAC CCAAGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Syntaxin 8 regulates platelet dense granule secretion, aggregation, and thrombus stability.
The Journal of biological chemistry290(3)1536-45(2015 Jan)
Golebiewska EM,Harper MT,Williams CM,Savage JS,Goggs R,Fischer von Mollard G,Poole AW

Histopathology reveals correlative and unique phenotypes in a high-throughput mouse phenotyping screen.
Disease models & mechanisms7(5)515-24(2014 May)
Adissu HA,Estabel J,Sunter D,Tuck E,Hooks Y,Carragher DM,Clarke K,Karp NA,,Newbigging S,Jones N,Morikawa L,White JK,McKerlie C

UVRAG is required for virus entry through combinatorial interaction with the class C-Vps complex and SNAREs.
Proceedings of the National Academy of Sciences of the United States of America111(7)2716-21(2014 Feb)
Pirooz SD,He S,Zhang T,Zhang X,Zhao Z,Oh S,O'Connell D,Khalilzadeh P,Amini-Bavil-Olyaee S,Farzan M,Liang C

Interaction between syntaxin 8 and HECTd3, a HECT domain ligase.
Cellular and molecular neurobiology29(1)115-21(2009 Feb)
Zhang L,Kang L,Bond W,Zhang N

The phagosomal proteome in interferon-gamma-activated macrophages.
Immunity30(1)143-54(2009 Jan)
Trost M,English L,Lemieux S,Courcelles M,Desjardins M,Thibault P

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Stx8 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

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ORF Insert Sequence:

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