Mapk6 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Mapk6
Entrez Gene ID	50772
Full Name	mitogen-activated protein kinase 6
Synonyms	2610021I23Rik,D130053K17Rik,Erk3,Mapk4,Mapk63,Prkm4,Prkm6
General protein information	Preferred Names mitogen-activated protein kinase 6 Names mitogen-activated protein kinase 6 Erk-3 related MAP kinase 6 extracellular signal-regulated kinase 3 mitogen activated protein kinase 4 protein kinase, mitogen activated kinase 4
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 9 Map Location: 9 D\|9 42.3 cM

mRNA and Protein(s)

mRNA	Protein	Name
XM_011242767.3	XP_011241069.1	mitogen-activated protein kinase 6 isoform X1
NM_015806.5	NP_056621.4	mitogen-activated protein kinase 6
XM_011242767.2	XP_011241069.1	mitogen-activated protein kinase 6 isoform X1
NM_027418.2	NP_081694.1	mitogen-activated protein kinase 6

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	MAPK6	XP_510409.2
	MAPK6	XP_001083937.2
Bos taurus (cattle)	MAPK6	XP_002691011.2
Mus musculus (house mouse)	Mapk6	NP_081694.1
Canis lupus familiaris (dog)	MAPK6	XP_005638475.1
Rattus norvegicus (Norway rat)	Mapk6	NP_113810.2
Gallus gallus (chicken)	MAPK6	NP_001025720.1
Danio rerio (zebrafish)	mapk6	NP_001039017.1
Homo sapiens (human)	MAPK6	NP_002739.1
Xenopus tropicalis (tropical clawed frog)	mapk6	XP_002936385.1

Gene Ontology
Bibliography

Related articles in PubMed

The atypical MAPK ERK3 controls positive selection of thymocytes.
Sirois J, Daudelin JF, Boulet S, Marquis M, Meloche S, Labrecque N
Immunology145(1)161-9(2015 May)

The catalytic activity of the mitogen-activated protein kinase extracellular signal-regulated kinase 3 is required to sustain CD4+ CD8+ thymocyte survival.
Marquis M, Daudelin JF, Boulet S, Sirois J, Crain K, Mathien S, Turgeon B, Rousseau J, Meloche S, Labrecque N
Molecular and cellular biology34(18)3374-87(2014 Sep)

The non-classical MAP kinase ERK3 controls T cell activation.
Marquis M, Boulet S, Mathien S, Rousseau J, Th?bault P, Daudelin JF, Rooney J, Turgeon B, Beauchamp C, Meloche S, Labrecque N
PloS one9(1)e86681(2014)

The extracellular signal-regulated kinase 3 (mitogen-activated protein kinase 6 [MAPK6])-MAPK-activated protein kinase 5 signaling complex regulates septin function and dendrite morphology.
Brand F, Schumacher S, Kant S, Menon MB, Simon R, Turgeon B, Britsch S, Meloche S, Gaestel M, Kotlyarov A
Molecular and cellular biology32(13)2467-78(2012 Jul)

ERKs induce expression of the transcriptional repressor Blimp-1 and subsequent plasma cell differentiation.
Yasuda T, Kometani K, Takahashi N, Imai Y, Aiba Y, Kurosaki T
Science signaling4(169)ra25(2011 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Results show that Cdo is important for full Abl kinase activity, and Abl is necessary for full activation of p38 MAPK, during myogenic differentiation.
Title: Cdo binds Abl to promote p38alpha/beta mitogen-activated protein kinase activity and myogenic differentiation.

p38gamma MAP kinase (SAPK3/p38gamma) was shown to catalyse phosphorylation of SAP97.
Title: p38gamma regulates the localisation of SAP97 in the cytoskeleton by modulating its interaction with GKAP.

Results demonstrate a specific interaction between extracellular signal-regulated kinase 3 (ERK3) and mitogen-activated protein kinase-activated protein kinase-5 (MK5).
Title: Activation of MK5/PRAK by the atypical MAP kinase ERK3 defines a novel signal transduction pathway.

Data show that extracellular-regulated kinase 3 (ERK3) specifically interacts with the MAPK-activated protein kinase 5 (MK5 or PRAK) in vitro and in vivo.
Title: Scaffolding by ERK3 regulates MK5 in development.

ERK3 biological activity is regulated by its cellular abundance through the control of protein stability
Title: Rapid turnover of extracellular signal-regulated kinase 3 by the ubiquitin-proteasome pathway defines a novel paradigm of mitogen-activated protein kinase regulation during cellular differentiation.

The following Mapk6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Mapk6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu04179	NM_015806.5 Latest version!	Mus musculus mitogen-activated protein kinase 6 (Mapk6), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
OMu04179	NM_027418.2 Latest version!	Mus musculus mitogen-activated protein kinase 6 (Mapk6), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
OMu04179	XM_011242767.3 Latest version!	Mus musculus mitogen-activated protein kinase 6 (Mapk6), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
View Old Accession Versions >>
OMu04179	XM_011242767.2	Mus musculus mitogen-activated protein kinase 6 (Mapk6), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Mapk6 ( NM_015806.5 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_056621.4 Mus musculus mitogen-activated protein kinase 6 (Mapk6), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu04179
Clone ID Related Accession (Same CDS sequence)	XM_011242767.3 , NM_015806.5 , XM_011242767.2 , NM_027418.2
Accession Version	NM_015806.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2163bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-20
Organism	Mus musculus(house mouse)
Product	mitogen-activated protein kinase 6
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CA325060.1, BC100385.1, BC048779.1, AK051508.1 and AC115880.11. On Nov 8, 2013 this sequence version replaced NM_015806.4. Transcript Variant: This variant (1) differs in the 5' UTR, compared to variant 2. Variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC100385.1, SRR7974084.14549.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849381, SAMN01164137 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCAGAGA AATTCGAAAG TCTCATGAAC ATTCATGGCT TTGATCTGGG CTCTAGGTAC 
ATGGACTTAA AACCATTGGG CTGCGGAGGC AATGGCTTGG TCTTTTCTGC TGTAGACAAT 
GACTGTGACA AAAGAGTAGC CATCAAGAAA ATTGTCCTCA CCGATCCCCA GAGTGTCAAA 
CATGCTCTCC GTGAAATCAA AATTATTCGA AGACTTGACC ACGATAACAT TGTGAAAGTG 
TTTGAAATTC TTGGTCCCAG TGGAAGCCAG TTAACAGACG ATGTGGGCTC TCTCACGGAG 
CTGAATAGCG TCTACATTGT TCAGGAGTAT ATGGAGACAG ACTTGGCGAA TGTGCTGGAG 
CAGGGCCCTT TACTGGAAGA GCATGCCAGG CTTTTCATGT ATCAGCTGCT ACGTGGGCTC 
AAATATATCC ATTCTGCAAA CGTACTGCAC AGAGATCTCA AGCCAGCTAA TCTTTTCATT 
AACACTGAAG ACTTGGTGCT GAAGATAGGT GACTTTGGCC TGGCACGGAT CATGGATCCT 
CATTATTCCC ATAAGGGTCA TCTTTCTGAA GGATTGGTTA CCAAATGGTA CAGATCTCCA 
CGGCTTTTAC TTTCTCCTAA TAATTACACT AAAGCCATTG ACATGTGGGC TGCAGGCTGC 
ATCTTTGCTG AGATGCTGAC TGGTAAAACC CTCTTTGCAG GTGCACATGA ACTTGAACAG 
ATGCAGCTGA TCCTCGACTC CATCCCTGTT GTGCACGAGG AGGATCGGCA GGAGCTTCTC 
AGCGTGATTC CAGTTTACAT TAGAAACGAC ATGACTGAGC CACACAGACC GCTCACTCAG 
CTGCTGCCGG GGATCAGCCG AGAAGCACTG GATTTCCTGG AGCAGATTCT GACTTTCAGC 
CCCATGGACC GGCTGACAGC TGAGGAAGCC CTTTCCCATC CTTACATGAG CATCTACTCC 
TTCCCGACGG ATGAGCCCAT CTCAAGCCAC CCTTTCCACA TAGAGGACGA AGTGGACGAC 
ATTTTGCTTA TGGATGAAAC ACACAGTCAC ATTTATAACT GGGAAAGGTA CCACGATTGT 
CAGTTCTCGG AGCATGACTG GCCTATTCAT AACAACTTTG ATATCGATGA GGTGCAGCTT 
GACCCAAGAG CTCTGTCTGA CGTCACCGAT GAAGAAGAAG TCCAAGTTGA TCCTCGAAAA 
TACTTGGATG GAGACCGAGA GAAGTATCTA GAGGATCCCG CCTTCGACAC CAGCTACTCT 
GCTGAACCCT GCTGGCAGTA CCCAGATCAC CACGAGAACA AGTACTGCGA TCTGGAGTGT 
AGCCACACCT GTAACTACAA AACAAGATCA TCACCATACT TAGATAACCT GGTGTGGAGG 
GAGAGCGAGG TTAACCATTA CTATGAGCCC AAGCTTATTA TAGATCTTTC CAACTGGAAA 
GAGCAAAGTA AAGAAAAATC CGATAAGAGA GGCAAGTCCA AGTGTGAGAG GAACGGGTTG 
GTCAAGGCGC AGATCGCGCT AGAGGAAGCA TCCCAGCAGC TGGCTGAGAG GGAGAGGGGC 
CAAGGCTTCG ACTTTGACTC CTTCATCGCG GGGACCATTC AGCTCAGTGC CCAGCATCAG 
TCTGCTGACG TAGTTGACAA GTTAAACGAC TTGAATAGCT CAGTGTCCCA GCTAGAATTG 
AAAAGCCTGA TATCCAAGTC AGTCAGCCGA GAAAAGCAAG AAAAGGGAAG GGCTAACCTG 
GCCCAGCTGG GAGCCTTGTA CCAGTCCTCC TGGGACAGCC AGTTTGTGAG TGGCGGGGAG 
GAGTGCTTCC TCATCAGTCA GTTTTGTTGT GAGGTCAGGA AGGACGAGCA TGCGGAGAAG 
GAGAACACCT ACACCAGCTA TTTGGACAAG TTTTTTAGCA GGAAGGAGGA TTCCGAAATG 
CTAGAAACTG AGCCAGTGGA GGAAGGGAAG CGTGGGGAGA GAGGCCGTGA GGCAGGGCTT 
CTGAGCGGCG GTGGGGAGTT CCTCCTGAGC AAGCAGCTGG AGTCCATAGG CACCCCGCAG 
TTCCACAGCC CAGTGGGGTC CCCACTCAAG TCCATCCAGG CCACCTTGAC ACCTTCCGCT 
ATGAAATCTT CCCCTCAAAT CCCTCACAAG ACATACAGCA GCATTCTGAA ACATCTGAAC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_056621.4
CDS	773..2935
Translation	MAEKFESLMNIHGFDLGSRYMDLKPLGCGGNGLVFSAVDNDCDKRVAIKKIVLTDPQSVKHALREIKIIRRLDHDNIVKVFEILGPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVLEQGPLLEEHARLFMYQLLRGLKYIHSANVLHRDLKPANLFINTEDLVLKIGDFGLARIMDPHYSHKGHLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLTGKTLFAGAHELEQMQLILDSIPVVHEEDRQELLSVIPVYIRNDMTEPHRPLTQLLPGISREALDFLEQILTFSPMDRLTAEEALSHPYMSIYSFPTDEPISSHPFHIEDEVDDILLMDETHSHIYNWERYHDCQFSEHDWPIHNNFDIDEVQLDPRALSDVTDEEEVQVDPRKYLDGDREKYLEDPAFDTSYSAEPCWQYPDHHENKYCDLECSHTCNYKTRSSPYLDNLVWRESEVNHYYEPKLIIDLSNWKEQSKEKSDKRGKSKCERNGLVKAQIALEEASQQLAERERGQGFDFDSFIAGTIQLSAQHQSADVVDKLNDLNSSVSQLELKSLISKSVSREKQEKGRANLAQLGALYQSSWDSQFVSGGEECFLISQFCCEVRKDEHAEKENTYTSYLDKFFSRKEDSEMLETEPVEEGKRGERGREAGLLSGGGEFLLSKQLESIGTPQFHSPVGSPLKSIQATLTPSAMKSSPQIPHKTYSSILKHLN

Target ORF information:

RefSeq Version	NM_015806.5
Organism	Mus musculus(house mouse)
Definition	Mus musculus mitogen-activated protein kinase 6 (Mapk6), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015806.5

ORF Insert Sequence:

ATGGCAGAGA AATTCGAAAG TCTCATGAAC ATTCATGGCT TTGATCTGGG CTCTAGGTAC 
ATGGACTTAA AACCATTGGG CTGCGGAGGC AATGGCTTGG TCTTTTCTGC TGTAGACAAT 
GACTGTGACA AAAGAGTAGC CATCAAGAAA ATTGTCCTCA CCGATCCCCA GAGTGTCAAA 
CATGCTCTCC GTGAAATCAA AATTATTCGA AGACTTGACC ACGATAACAT TGTGAAAGTG 
TTTGAAATTC TTGGTCCCAG TGGAAGCCAG TTAACAGACG ATGTGGGCTC TCTCACGGAG 
CTGAATAGCG TCTACATTGT TCAGGAGTAT ATGGAGACAG ACTTGGCGAA TGTGCTGGAG 
CAGGGCCCTT TACTGGAAGA GCATGCCAGG CTTTTCATGT ATCAGCTGCT ACGTGGGCTC 
AAATATATCC ATTCTGCAAA CGTACTGCAC AGAGATCTCA AGCCAGCTAA TCTTTTCATT 
AACACTGAAG ACTTGGTGCT GAAGATAGGT GACTTTGGCC TGGCACGGAT CATGGATCCT 
CATTATTCCC ATAAGGGTCA TCTTTCTGAA GGATTGGTTA CCAAATGGTA CAGATCTCCA 
CGGCTTTTAC TTTCTCCTAA TAATTACACT AAAGCCATTG ACATGTGGGC TGCAGGCTGC 
ATCTTTGCTG AGATGCTGAC TGGTAAAACC CTCTTTGCAG GTGCACATGA ACTTGAACAG 
ATGCAGCTGA TCCTCGACTC CATCCCTGTT GTGCACGAGG AGGATCGGCA GGAGCTTCTC 
AGCGTGATTC CAGTTTACAT TAGAAACGAC ATGACTGAGC CACACAGACC GCTCACTCAG 
CTGCTGCCGG GGATCAGCCG AGAAGCACTG GATTTCCTGG AGCAGATTCT GACTTTCAGC 
CCCATGGACC GGCTGACAGC TGAGGAAGCC CTTTCCCATC CTTACATGAG CATCTACTCC 
TTCCCGACGG ATGAGCCCAT CTCAAGCCAC CCTTTCCACA TAGAGGACGA AGTGGACGAC 
ATTTTGCTTA TGGATGAAAC ACACAGTCAC ATTTATAACT GGGAAAGGTA CCACGATTGT 
CAGTTCTCGG AGCATGACTG GCCTATTCAT AACAACTTTG ATATCGATGA GGTGCAGCTT 
GACCCAAGAG CTCTGTCTGA CGTCACCGAT GAAGAAGAAG TCCAAGTTGA TCCTCGAAAA 
TACTTGGATG GAGACCGAGA GAAGTATCTA GAGGATCCCG CCTTCGACAC CAGCTACTCT 
GCTGAACCCT GCTGGCAGTA CCCAGATCAC CACGAGAACA AGTACTGCGA TCTGGAGTGT 
AGCCACACCT GTAACTACAA AACAAGATCA TCACCATACT TAGATAACCT GGTGTGGAGG 
GAGAGCGAGG TTAACCATTA CTATGAGCCC AAGCTTATTA TAGATCTTTC CAACTGGAAA 
GAGCAAAGTA AAGAAAAATC CGATAAGAGA GGCAAGTCCA AGTGTGAGAG GAACGGGTTG 
GTCAAGGCGC AGATCGCGCT AGAGGAAGCA TCCCAGCAGC TGGCTGAGAG GGAGAGGGGC 
CAAGGCTTCG ACTTTGACTC CTTCATCGCG GGGACCATTC AGCTCAGTGC CCAGCATCAG 
TCTGCTGACG TAGTTGACAA GTTAAACGAC TTGAATAGCT CAGTGTCCCA GCTAGAATTG 
AAAAGCCTGA TATCCAAGTC AGTCAGCCGA GAAAAGCAAG AAAAGGGAAG GGCTAACCTG 
GCCCAGCTGG GAGCCTTGTA CCAGTCCTCC TGGGACAGCC AGTTTGTGAG TGGCGGGGAG 
GAGTGCTTCC TCATCAGTCA GTTTTGTTGT GAGGTCAGGA AGGACGAGCA TGCGGAGAAG 
GAGAACACCT ACACCAGCTA TTTGGACAAG TTTTTTAGCA GGAAGGAGGA TTCCGAAATG 
CTAGAAACTG AGCCAGTGGA GGAAGGGAAG CGTGGGGAGA GAGGCCGTGA GGCAGGGCTT 
CTGAGCGGCG GTGGGGAGTT CCTCCTGAGC AAGCAGCTGG AGTCCATAGG CACCCCGCAG 
TTCCACAGCC CAGTGGGGTC CCCACTCAAG TCCATCCAGG CCACCTTGAC ACCTTCCGCT 
ATGAAATCTT CCCCTCAAAT CCCTCACAAG ACATACAGCA GCATTCTGAA ACATCTGAAC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Mapk6 ( NM_027418.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_081694.1 Mus musculus mitogen-activated protein kinase 6 (Mapk6), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu04179
Clone ID Related Accession (Same CDS sequence)	XM_011242767.3 , NM_015806.5 , XM_011242767.2 , NM_027418.2
Accession Version	NM_027418.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2163bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-20
Organism	Mus musculus(house mouse)
Product	mitogen-activated protein kinase 6
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY737145.1, BC100385.1, BC048779.1, AK051508.1 and AC115880.11. On Nov 8, 2013 this sequence version replaced NM_027418.1. Transcript Variant: This variant (2) represents the longer transcript. Variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: SRR1660817.6771.1, SRR1660811.163066.1 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMN00849381, SAMN01164137 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCAGAGA AATTCGAAAG TCTCATGAAC ATTCATGGCT TTGATCTGGG CTCTAGGTAC 
ATGGACTTAA AACCATTGGG CTGCGGAGGC AATGGCTTGG TCTTTTCTGC TGTAGACAAT 
GACTGTGACA AAAGAGTAGC CATCAAGAAA ATTGTCCTCA CCGATCCCCA GAGTGTCAAA 
CATGCTCTCC GTGAAATCAA AATTATTCGA AGACTTGACC ACGATAACAT TGTGAAAGTG 
TTTGAAATTC TTGGTCCCAG TGGAAGCCAG TTAACAGACG ATGTGGGCTC TCTCACGGAG 
CTGAATAGCG TCTACATTGT TCAGGAGTAT ATGGAGACAG ACTTGGCGAA TGTGCTGGAG 
CAGGGCCCTT TACTGGAAGA GCATGCCAGG CTTTTCATGT ATCAGCTGCT ACGTGGGCTC 
AAATATATCC ATTCTGCAAA CGTACTGCAC AGAGATCTCA AGCCAGCTAA TCTTTTCATT 
AACACTGAAG ACTTGGTGCT GAAGATAGGT GACTTTGGCC TGGCACGGAT CATGGATCCT 
CATTATTCCC ATAAGGGTCA TCTTTCTGAA GGATTGGTTA CCAAATGGTA CAGATCTCCA 
CGGCTTTTAC TTTCTCCTAA TAATTACACT AAAGCCATTG ACATGTGGGC TGCAGGCTGC 
ATCTTTGCTG AGATGCTGAC TGGTAAAACC CTCTTTGCAG GTGCACATGA ACTTGAACAG 
ATGCAGCTGA TCCTCGACTC CATCCCTGTT GTGCACGAGG AGGATCGGCA GGAGCTTCTC 
AGCGTGATTC CAGTTTACAT TAGAAACGAC ATGACTGAGC CACACAGACC GCTCACTCAG 
CTGCTGCCGG GGATCAGCCG AGAAGCACTG GATTTCCTGG AGCAGATTCT GACTTTCAGC 
CCCATGGACC GGCTGACAGC TGAGGAAGCC CTTTCCCATC CTTACATGAG CATCTACTCC 
TTCCCGACGG ATGAGCCCAT CTCAAGCCAC CCTTTCCACA TAGAGGACGA AGTGGACGAC 
ATTTTGCTTA TGGATGAAAC ACACAGTCAC ATTTATAACT GGGAAAGGTA CCACGATTGT 
CAGTTCTCGG AGCATGACTG GCCTATTCAT AACAACTTTG ATATCGATGA GGTGCAGCTT 
GACCCAAGAG CTCTGTCTGA CGTCACCGAT GAAGAAGAAG TCCAAGTTGA TCCTCGAAAA 
TACTTGGATG GAGACCGAGA GAAGTATCTA GAGGATCCCG CCTTCGACAC CAGCTACTCT 
GCTGAACCCT GCTGGCAGTA CCCAGATCAC CACGAGAACA AGTACTGCGA TCTGGAGTGT 
AGCCACACCT GTAACTACAA AACAAGATCA TCACCATACT TAGATAACCT GGTGTGGAGG 
GAGAGCGAGG TTAACCATTA CTATGAGCCC AAGCTTATTA TAGATCTTTC CAACTGGAAA 
GAGCAAAGTA AAGAAAAATC CGATAAGAGA GGCAAGTCCA AGTGTGAGAG GAACGGGTTG 
GTCAAGGCGC AGATCGCGCT AGAGGAAGCA TCCCAGCAGC TGGCTGAGAG GGAGAGGGGC 
CAAGGCTTCG ACTTTGACTC CTTCATCGCG GGGACCATTC AGCTCAGTGC CCAGCATCAG 
TCTGCTGACG TAGTTGACAA GTTAAACGAC TTGAATAGCT CAGTGTCCCA GCTAGAATTG 
AAAAGCCTGA TATCCAAGTC AGTCAGCCGA GAAAAGCAAG AAAAGGGAAG GGCTAACCTG 
GCCCAGCTGG GAGCCTTGTA CCAGTCCTCC TGGGACAGCC AGTTTGTGAG TGGCGGGGAG 
GAGTGCTTCC TCATCAGTCA GTTTTGTTGT GAGGTCAGGA AGGACGAGCA TGCGGAGAAG 
GAGAACACCT ACACCAGCTA TTTGGACAAG TTTTTTAGCA GGAAGGAGGA TTCCGAAATG 
CTAGAAACTG AGCCAGTGGA GGAAGGGAAG CGTGGGGAGA GAGGCCGTGA GGCAGGGCTT 
CTGAGCGGCG GTGGGGAGTT CCTCCTGAGC AAGCAGCTGG AGTCCATAGG CACCCCGCAG 
TTCCACAGCC CAGTGGGGTC CCCACTCAAG TCCATCCAGG CCACCTTGAC ACCTTCCGCT 
ATGAAATCTT CCCCTCAAAT CCCTCACAAG ACATACAGCA GCATTCTGAA ACATCTGAAC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_081694.1
CDS	777..2939
Translation	MAEKFESLMNIHGFDLGSRYMDLKPLGCGGNGLVFSAVDNDCDKRVAIKKIVLTDPQSVKHALREIKIIRRLDHDNIVKVFEILGPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVLEQGPLLEEHARLFMYQLLRGLKYIHSANVLHRDLKPANLFINTEDLVLKIGDFGLARIMDPHYSHKGHLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLTGKTLFAGAHELEQMQLILDSIPVVHEEDRQELLSVIPVYIRNDMTEPHRPLTQLLPGISREALDFLEQILTFSPMDRLTAEEALSHPYMSIYSFPTDEPISSHPFHIEDEVDDILLMDETHSHIYNWERYHDCQFSEHDWPIHNNFDIDEVQLDPRALSDVTDEEEVQVDPRKYLDGDREKYLEDPAFDTSYSAEPCWQYPDHHENKYCDLECSHTCNYKTRSSPYLDNLVWRESEVNHYYEPKLIIDLSNWKEQSKEKSDKRGKSKCERNGLVKAQIALEEASQQLAERERGQGFDFDSFIAGTIQLSAQHQSADVVDKLNDLNSSVSQLELKSLISKSVSREKQEKGRANLAQLGALYQSSWDSQFVSGGEECFLISQFCCEVRKDEHAEKENTYTSYLDKFFSRKEDSEMLETEPVEEGKRGERGREAGLLSGGGEFLLSKQLESIGTPQFHSPVGSPLKSIQATLTPSAMKSSPQIPHKTYSSILKHLN

Target ORF information:

RefSeq Version	NM_027418.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus mitogen-activated protein kinase 6 (Mapk6), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_027418.2

ORF Insert Sequence:

ATGGCAGAGA AATTCGAAAG TCTCATGAAC ATTCATGGCT TTGATCTGGG CTCTAGGTAC 
ATGGACTTAA AACCATTGGG CTGCGGAGGC AATGGCTTGG TCTTTTCTGC TGTAGACAAT 
GACTGTGACA AAAGAGTAGC CATCAAGAAA ATTGTCCTCA CCGATCCCCA GAGTGTCAAA 
CATGCTCTCC GTGAAATCAA AATTATTCGA AGACTTGACC ACGATAACAT TGTGAAAGTG 
TTTGAAATTC TTGGTCCCAG TGGAAGCCAG TTAACAGACG ATGTGGGCTC TCTCACGGAG 
CTGAATAGCG TCTACATTGT TCAGGAGTAT ATGGAGACAG ACTTGGCGAA TGTGCTGGAG 
CAGGGCCCTT TACTGGAAGA GCATGCCAGG CTTTTCATGT ATCAGCTGCT ACGTGGGCTC 
AAATATATCC ATTCTGCAAA CGTACTGCAC AGAGATCTCA AGCCAGCTAA TCTTTTCATT 
AACACTGAAG ACTTGGTGCT GAAGATAGGT GACTTTGGCC TGGCACGGAT CATGGATCCT 
CATTATTCCC ATAAGGGTCA TCTTTCTGAA GGATTGGTTA CCAAATGGTA CAGATCTCCA 
CGGCTTTTAC TTTCTCCTAA TAATTACACT AAAGCCATTG ACATGTGGGC TGCAGGCTGC 
ATCTTTGCTG AGATGCTGAC TGGTAAAACC CTCTTTGCAG GTGCACATGA ACTTGAACAG 
ATGCAGCTGA TCCTCGACTC CATCCCTGTT GTGCACGAGG AGGATCGGCA GGAGCTTCTC 
AGCGTGATTC CAGTTTACAT TAGAAACGAC ATGACTGAGC CACACAGACC GCTCACTCAG 
CTGCTGCCGG GGATCAGCCG AGAAGCACTG GATTTCCTGG AGCAGATTCT GACTTTCAGC 
CCCATGGACC GGCTGACAGC TGAGGAAGCC CTTTCCCATC CTTACATGAG CATCTACTCC 
TTCCCGACGG ATGAGCCCAT CTCAAGCCAC CCTTTCCACA TAGAGGACGA AGTGGACGAC 
ATTTTGCTTA TGGATGAAAC ACACAGTCAC ATTTATAACT GGGAAAGGTA CCACGATTGT 
CAGTTCTCGG AGCATGACTG GCCTATTCAT AACAACTTTG ATATCGATGA GGTGCAGCTT 
GACCCAAGAG CTCTGTCTGA CGTCACCGAT GAAGAAGAAG TCCAAGTTGA TCCTCGAAAA 
TACTTGGATG GAGACCGAGA GAAGTATCTA GAGGATCCCG CCTTCGACAC CAGCTACTCT 
GCTGAACCCT GCTGGCAGTA CCCAGATCAC CACGAGAACA AGTACTGCGA TCTGGAGTGT 
AGCCACACCT GTAACTACAA AACAAGATCA TCACCATACT TAGATAACCT GGTGTGGAGG 
GAGAGCGAGG TTAACCATTA CTATGAGCCC AAGCTTATTA TAGATCTTTC CAACTGGAAA 
GAGCAAAGTA AAGAAAAATC CGATAAGAGA GGCAAGTCCA AGTGTGAGAG GAACGGGTTG 
GTCAAGGCGC AGATCGCGCT AGAGGAAGCA TCCCAGCAGC TGGCTGAGAG GGAGAGGGGC 
CAAGGCTTCG ACTTTGACTC CTTCATCGCG GGGACCATTC AGCTCAGTGC CCAGCATCAG 
TCTGCTGACG TAGTTGACAA GTTAAACGAC TTGAATAGCT CAGTGTCCCA GCTAGAATTG 
AAAAGCCTGA TATCCAAGTC AGTCAGCCGA GAAAAGCAAG AAAAGGGAAG GGCTAACCTG 
GCCCAGCTGG GAGCCTTGTA CCAGTCCTCC TGGGACAGCC AGTTTGTGAG TGGCGGGGAG 
GAGTGCTTCC TCATCAGTCA GTTTTGTTGT GAGGTCAGGA AGGACGAGCA TGCGGAGAAG 
GAGAACACCT ACACCAGCTA TTTGGACAAG TTTTTTAGCA GGAAGGAGGA TTCCGAAATG 
CTAGAAACTG AGCCAGTGGA GGAAGGGAAG CGTGGGGAGA GAGGCCGTGA GGCAGGGCTT 
CTGAGCGGCG GTGGGGAGTT CCTCCTGAGC AAGCAGCTGG AGTCCATAGG CACCCCGCAG 
TTCCACAGCC CAGTGGGGTC CCCACTCAAG TCCATCCAGG CCACCTTGAC ACCTTCCGCT 
ATGAAATCTT CCCCTCAAAT CCCTCACAAG ACATACAGCA GCATTCTGAA ACATCTGAAC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Mapk6 ( XM_011242767.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011241069.1 Mus musculus mitogen-activated protein kinase 6 (Mapk6), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu04179
Clone ID Related Accession (Same CDS sequence)	XM_011242767.3 , NM_015806.5 , XM_011242767.2 , NM_027418.2
Accession Version	XM_011242767.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2163bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	mitogen-activated protein kinase 6 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000075.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_011242767.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCAGAGA AATTCGAAAG TCTCATGAAC ATTCATGGCT TTGATCTGGG CTCTAGGTAC 
ATGGACTTAA AACCATTGGG CTGCGGAGGC AATGGCTTGG TCTTTTCTGC TGTAGACAAT 
GACTGTGACA AAAGAGTAGC CATCAAGAAA ATTGTCCTCA CCGATCCCCA GAGTGTCAAA 
CATGCTCTCC GTGAAATCAA AATTATTCGA AGACTTGACC ACGATAACAT TGTGAAAGTG 
TTTGAAATTC TTGGTCCCAG TGGAAGCCAG TTAACAGACG ATGTGGGCTC TCTCACGGAG 
CTGAATAGCG TCTACATTGT TCAGGAGTAT ATGGAGACAG ACTTGGCGAA TGTGCTGGAG 
CAGGGCCCTT TACTGGAAGA GCATGCCAGG CTTTTCATGT ATCAGCTGCT ACGTGGGCTC 
AAATATATCC ATTCTGCAAA CGTACTGCAC AGAGATCTCA AGCCAGCTAA TCTTTTCATT 
AACACTGAAG ACTTGGTGCT GAAGATAGGT GACTTTGGCC TGGCACGGAT CATGGATCCT 
CATTATTCCC ATAAGGGTCA TCTTTCTGAA GGATTGGTTA CCAAATGGTA CAGATCTCCA 
CGGCTTTTAC TTTCTCCTAA TAATTACACT AAAGCCATTG ACATGTGGGC TGCAGGCTGC 
ATCTTTGCTG AGATGCTGAC TGGTAAAACC CTCTTTGCAG GTGCACATGA ACTTGAACAG 
ATGCAGCTGA TCCTCGACTC CATCCCTGTT GTGCACGAGG AGGATCGGCA GGAGCTTCTC 
AGCGTGATTC CAGTTTACAT TAGAAACGAC ATGACTGAGC CACACAGACC GCTCACTCAG 
CTGCTGCCGG GGATCAGCCG AGAAGCACTG GATTTCCTGG AGCAGATTCT GACTTTCAGC 
CCCATGGACC GGCTGACAGC TGAGGAAGCC CTTTCCCATC CTTACATGAG CATCTACTCC 
TTCCCGACGG ATGAGCCCAT CTCAAGCCAC CCTTTCCACA TAGAGGACGA AGTGGACGAC 
ATTTTGCTTA TGGATGAAAC ACACAGTCAC ATTTATAACT GGGAAAGGTA CCACGATTGT 
CAGTTCTCGG AGCATGACTG GCCTATTCAT AACAACTTTG ATATCGATGA GGTGCAGCTT 
GACCCAAGAG CTCTGTCTGA CGTCACCGAT GAAGAAGAAG TCCAAGTTGA TCCTCGAAAA 
TACTTGGATG GAGACCGAGA GAAGTATCTA GAGGATCCCG CCTTCGACAC CAGCTACTCT 
GCTGAACCCT GCTGGCAGTA CCCAGATCAC CACGAGAACA AGTACTGCGA TCTGGAGTGT 
AGCCACACCT GTAACTACAA AACAAGATCA TCACCATACT TAGATAACCT GGTGTGGAGG 
GAGAGCGAGG TTAACCATTA CTATGAGCCC AAGCTTATTA TAGATCTTTC CAACTGGAAA 
GAGCAAAGTA AAGAAAAATC CGATAAGAGA GGCAAGTCCA AGTGTGAGAG GAACGGGTTG 
GTCAAGGCGC AGATCGCGCT AGAGGAAGCA TCCCAGCAGC TGGCTGAGAG GGAGAGGGGC 
CAAGGCTTCG ACTTTGACTC CTTCATCGCG GGGACCATTC AGCTCAGTGC CCAGCATCAG 
TCTGCTGACG TAGTTGACAA GTTAAACGAC TTGAATAGCT CAGTGTCCCA GCTAGAATTG 
AAAAGCCTGA TATCCAAGTC AGTCAGCCGA GAAAAGCAAG AAAAGGGAAG GGCTAACCTG 
GCCCAGCTGG GAGCCTTGTA CCAGTCCTCC TGGGACAGCC AGTTTGTGAG TGGCGGGGAG 
GAGTGCTTCC TCATCAGTCA GTTTTGTTGT GAGGTCAGGA AGGACGAGCA TGCGGAGAAG 
GAGAACACCT ACACCAGCTA TTTGGACAAG TTTTTTAGCA GGAAGGAGGA TTCCGAAATG 
CTAGAAACTG AGCCAGTGGA GGAAGGGAAG CGTGGGGAGA GAGGCCGTGA GGCAGGGCTT 
CTGAGCGGCG GTGGGGAGTT CCTCCTGAGC AAGCAGCTGG AGTCCATAGG CACCCCGCAG 
TTCCACAGCC CAGTGGGGTC CCCACTCAAG TCCATCCAGG CCACCTTGAC ACCTTCCGCT 
ATGAAATCTT CCCCTCAAAT CCCTCACAAG ACATACAGCA GCATTCTGAA ACATCTGAAC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011241069.1
CDS	784..2946
Translation	MAEKFESLMNIHGFDLGSRYMDLKPLGCGGNGLVFSAVDNDCDKRVAIKKIVLTDPQSVKHALREIKIIRRLDHDNIVKVFEILGPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVLEQGPLLEEHARLFMYQLLRGLKYIHSANVLHRDLKPANLFINTEDLVLKIGDFGLARIMDPHYSHKGHLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLTGKTLFAGAHELEQMQLILDSIPVVHEEDRQELLSVIPVYIRNDMTEPHRPLTQLLPGISREALDFLEQILTFSPMDRLTAEEALSHPYMSIYSFPTDEPISSHPFHIEDEVDDILLMDETHSHIYNWERYHDCQFSEHDWPIHNNFDIDEVQLDPRALSDVTDEEEVQVDPRKYLDGDREKYLEDPAFDTSYSAEPCWQYPDHHENKYCDLECSHTCNYKTRSSPYLDNLVWRESEVNHYYEPKLIIDLSNWKEQSKEKSDKRGKSKCERNGLVKAQIALEEASQQLAERERGQGFDFDSFIAGTIQLSAQHQSADVVDKLNDLNSSVSQLELKSLISKSVSREKQEKGRANLAQLGALYQSSWDSQFVSGGEECFLISQFCCEVRKDEHAEKENTYTSYLDKFFSRKEDSEMLETEPVEEGKRGERGREAGLLSGGGEFLLSKQLESIGTPQFHSPVGSPLKSIQATLTPSAMKSSPQIPHKTYSSILKHLN

Target ORF information:

RefSeq Version	XM_011242767.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus mitogen-activated protein kinase 6 (Mapk6), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011242767.2

ORF Insert Sequence:

ATGGCAGAGA AATTCGAAAG TCTCATGAAC ATTCATGGCT TTGATCTGGG CTCTAGGTAC 
ATGGACTTAA AACCATTGGG CTGCGGAGGC AATGGCTTGG TCTTTTCTGC TGTAGACAAT 
GACTGTGACA AAAGAGTAGC CATCAAGAAA ATTGTCCTCA CCGATCCCCA GAGTGTCAAA 
CATGCTCTCC GTGAAATCAA AATTATTCGA AGACTTGACC ACGATAACAT TGTGAAAGTG 
TTTGAAATTC TTGGTCCCAG TGGAAGCCAG TTAACAGACG ATGTGGGCTC TCTCACGGAG 
CTGAATAGCG TCTACATTGT TCAGGAGTAT ATGGAGACAG ACTTGGCGAA TGTGCTGGAG 
CAGGGCCCTT TACTGGAAGA GCATGCCAGG CTTTTCATGT ATCAGCTGCT ACGTGGGCTC 
AAATATATCC ATTCTGCAAA CGTACTGCAC AGAGATCTCA AGCCAGCTAA TCTTTTCATT 
AACACTGAAG ACTTGGTGCT GAAGATAGGT GACTTTGGCC TGGCACGGAT CATGGATCCT 
CATTATTCCC ATAAGGGTCA TCTTTCTGAA GGATTGGTTA CCAAATGGTA CAGATCTCCA 
CGGCTTTTAC TTTCTCCTAA TAATTACACT AAAGCCATTG ACATGTGGGC TGCAGGCTGC 
ATCTTTGCTG AGATGCTGAC TGGTAAAACC CTCTTTGCAG GTGCACATGA ACTTGAACAG 
ATGCAGCTGA TCCTCGACTC CATCCCTGTT GTGCACGAGG AGGATCGGCA GGAGCTTCTC 
AGCGTGATTC CAGTTTACAT TAGAAACGAC ATGACTGAGC CACACAGACC GCTCACTCAG 
CTGCTGCCGG GGATCAGCCG AGAAGCACTG GATTTCCTGG AGCAGATTCT GACTTTCAGC 
CCCATGGACC GGCTGACAGC TGAGGAAGCC CTTTCCCATC CTTACATGAG CATCTACTCC 
TTCCCGACGG ATGAGCCCAT CTCAAGCCAC CCTTTCCACA TAGAGGACGA AGTGGACGAC 
ATTTTGCTTA TGGATGAAAC ACACAGTCAC ATTTATAACT GGGAAAGGTA CCACGATTGT 
CAGTTCTCGG AGCATGACTG GCCTATTCAT AACAACTTTG ATATCGATGA GGTGCAGCTT 
GACCCAAGAG CTCTGTCTGA CGTCACCGAT GAAGAAGAAG TCCAAGTTGA TCCTCGAAAA 
TACTTGGATG GAGACCGAGA GAAGTATCTA GAGGATCCCG CCTTCGACAC CAGCTACTCT 
GCTGAACCCT GCTGGCAGTA CCCAGATCAC CACGAGAACA AGTACTGCGA TCTGGAGTGT 
AGCCACACCT GTAACTACAA AACAAGATCA TCACCATACT TAGATAACCT GGTGTGGAGG 
GAGAGCGAGG TTAACCATTA CTATGAGCCC AAGCTTATTA TAGATCTTTC CAACTGGAAA 
GAGCAAAGTA AAGAAAAATC CGATAAGAGA GGCAAGTCCA AGTGTGAGAG GAACGGGTTG 
GTCAAGGCGC AGATCGCGCT AGAGGAAGCA TCCCAGCAGC TGGCTGAGAG GGAGAGGGGC 
CAAGGCTTCG ACTTTGACTC CTTCATCGCG GGGACCATTC AGCTCAGTGC CCAGCATCAG 
TCTGCTGACG TAGTTGACAA GTTAAACGAC TTGAATAGCT CAGTGTCCCA GCTAGAATTG 
AAAAGCCTGA TATCCAAGTC AGTCAGCCGA GAAAAGCAAG AAAAGGGAAG GGCTAACCTG 
GCCCAGCTGG GAGCCTTGTA CCAGTCCTCC TGGGACAGCC AGTTTGTGAG TGGCGGGGAG 
GAGTGCTTCC TCATCAGTCA GTTTTGTTGT GAGGTCAGGA AGGACGAGCA TGCGGAGAAG 
GAGAACACCT ACACCAGCTA TTTGGACAAG TTTTTTAGCA GGAAGGAGGA TTCCGAAATG 
CTAGAAACTG AGCCAGTGGA GGAAGGGAAG CGTGGGGAGA GAGGCCGTGA GGCAGGGCTT 
CTGAGCGGCG GTGGGGAGTT CCTCCTGAGC AAGCAGCTGG AGTCCATAGG CACCCCGCAG 
TTCCACAGCC CAGTGGGGTC CCCACTCAAG TCCATCCAGG CCACCTTGAC ACCTTCCGCT 
ATGAAATCTT CCCCTCAAAT CCCTCACAAG ACATACAGCA GCATTCTGAA ACATCTGAAC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Mapk6 ( XM_011242767.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011241069.1 Mus musculus mitogen-activated protein kinase 6 (Mapk6), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu04179
Clone ID Related Accession (Same CDS sequence)	XM_011242767.3 , NM_015806.5 , XM_011242767.2 , NM_027418.2
Accession Version	XM_011242767.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2163bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	mitogen-activated protein kinase 6 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000075.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_011242767.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCAGAGA AATTCGAAAG TCTCATGAAC ATTCATGGCT TTGATCTGGG CTCTAGGTAC 
ATGGACTTAA AACCATTGGG CTGCGGAGGC AATGGCTTGG TCTTTTCTGC TGTAGACAAT 
GACTGTGACA AAAGAGTAGC CATCAAGAAA ATTGTCCTCA CCGATCCCCA GAGTGTCAAA 
CATGCTCTCC GTGAAATCAA AATTATTCGA AGACTTGACC ACGATAACAT TGTGAAAGTG 
TTTGAAATTC TTGGTCCCAG TGGAAGCCAG TTAACAGACG ATGTGGGCTC TCTCACGGAG 
CTGAATAGCG TCTACATTGT TCAGGAGTAT ATGGAGACAG ACTTGGCGAA TGTGCTGGAG 
CAGGGCCCTT TACTGGAAGA GCATGCCAGG CTTTTCATGT ATCAGCTGCT ACGTGGGCTC 
AAATATATCC ATTCTGCAAA CGTACTGCAC AGAGATCTCA AGCCAGCTAA TCTTTTCATT 
AACACTGAAG ACTTGGTGCT GAAGATAGGT GACTTTGGCC TGGCACGGAT CATGGATCCT 
CATTATTCCC ATAAGGGTCA TCTTTCTGAA GGATTGGTTA CCAAATGGTA CAGATCTCCA 
CGGCTTTTAC TTTCTCCTAA TAATTACACT AAAGCCATTG ACATGTGGGC TGCAGGCTGC 
ATCTTTGCTG AGATGCTGAC TGGTAAAACC CTCTTTGCAG GTGCACATGA ACTTGAACAG 
ATGCAGCTGA TCCTCGACTC CATCCCTGTT GTGCACGAGG AGGATCGGCA GGAGCTTCTC 
AGCGTGATTC CAGTTTACAT TAGAAACGAC ATGACTGAGC CACACAGACC GCTCACTCAG 
CTGCTGCCGG GGATCAGCCG AGAAGCACTG GATTTCCTGG AGCAGATTCT GACTTTCAGC 
CCCATGGACC GGCTGACAGC TGAGGAAGCC CTTTCCCATC CTTACATGAG CATCTACTCC 
TTCCCGACGG ATGAGCCCAT CTCAAGCCAC CCTTTCCACA TAGAGGACGA AGTGGACGAC 
ATTTTGCTTA TGGATGAAAC ACACAGTCAC ATTTATAACT GGGAAAGGTA CCACGATTGT 
CAGTTCTCGG AGCATGACTG GCCTATTCAT AACAACTTTG ATATCGATGA GGTGCAGCTT 
GACCCAAGAG CTCTGTCTGA CGTCACCGAT GAAGAAGAAG TCCAAGTTGA TCCTCGAAAA 
TACTTGGATG GAGACCGAGA GAAGTATCTA GAGGATCCCG CCTTCGACAC CAGCTACTCT 
GCTGAACCCT GCTGGCAGTA CCCAGATCAC CACGAGAACA AGTACTGCGA TCTGGAGTGT 
AGCCACACCT GTAACTACAA AACAAGATCA TCACCATACT TAGATAACCT GGTGTGGAGG 
GAGAGCGAGG TTAACCATTA CTATGAGCCC AAGCTTATTA TAGATCTTTC CAACTGGAAA 
GAGCAAAGTA AAGAAAAATC CGATAAGAGA GGCAAGTCCA AGTGTGAGAG GAACGGGTTG 
GTCAAGGCGC AGATCGCGCT AGAGGAAGCA TCCCAGCAGC TGGCTGAGAG GGAGAGGGGC 
CAAGGCTTCG ACTTTGACTC CTTCATCGCG GGGACCATTC AGCTCAGTGC CCAGCATCAG 
TCTGCTGACG TAGTTGACAA GTTAAACGAC TTGAATAGCT CAGTGTCCCA GCTAGAATTG 
AAAAGCCTGA TATCCAAGTC AGTCAGCCGA GAAAAGCAAG AAAAGGGAAG GGCTAACCTG 
GCCCAGCTGG GAGCCTTGTA CCAGTCCTCC TGGGACAGCC AGTTTGTGAG TGGCGGGGAG 
GAGTGCTTCC TCATCAGTCA GTTTTGTTGT GAGGTCAGGA AGGACGAGCA TGCGGAGAAG 
GAGAACACCT ACACCAGCTA TTTGGACAAG TTTTTTAGCA GGAAGGAGGA TTCCGAAATG 
CTAGAAACTG AGCCAGTGGA GGAAGGGAAG CGTGGGGAGA GAGGCCGTGA GGCAGGGCTT 
CTGAGCGGCG GTGGGGAGTT CCTCCTGAGC AAGCAGCTGG AGTCCATAGG CACCCCGCAG 
TTCCACAGCC CAGTGGGGTC CCCACTCAAG TCCATCCAGG CCACCTTGAC ACCTTCCGCT 
ATGAAATCTT CCCCTCAAAT CCCTCACAAG ACATACAGCA GCATTCTGAA ACATCTGAAC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011241069.1
CDS	703..2865
Translation	MAEKFESLMNIHGFDLGSRYMDLKPLGCGGNGLVFSAVDNDCDKRVAIKKIVLTDPQSVKHALREIKIIRRLDHDNIVKVFEILGPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVLEQGPLLEEHARLFMYQLLRGLKYIHSANVLHRDLKPANLFINTEDLVLKIGDFGLARIMDPHYSHKGHLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLTGKTLFAGAHELEQMQLILDSIPVVHEEDRQELLSVIPVYIRNDMTEPHRPLTQLLPGISREALDFLEQILTFSPMDRLTAEEALSHPYMSIYSFPTDEPISSHPFHIEDEVDDILLMDETHSHIYNWERYHDCQFSEHDWPIHNNFDIDEVQLDPRALSDVTDEEEVQVDPRKYLDGDREKYLEDPAFDTSYSAEPCWQYPDHHENKYCDLECSHTCNYKTRSSPYLDNLVWRESEVNHYYEPKLIIDLSNWKEQSKEKSDKRGKSKCERNGLVKAQIALEEASQQLAERERGQGFDFDSFIAGTIQLSAQHQSADVVDKLNDLNSSVSQLELKSLISKSVSREKQEKGRANLAQLGALYQSSWDSQFVSGGEECFLISQFCCEVRKDEHAEKENTYTSYLDKFFSRKEDSEMLETEPVEEGKRGERGREAGLLSGGGEFLLSKQLESIGTPQFHSPVGSPLKSIQATLTPSAMKSSPQIPHKTYSSILKHLN

Target ORF information:

RefSeq Version	XM_011242767.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus mitogen-activated protein kinase 6 (Mapk6), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011242767.3

ORF Insert Sequence:

ATGGCAGAGA AATTCGAAAG TCTCATGAAC ATTCATGGCT TTGATCTGGG CTCTAGGTAC 
ATGGACTTAA AACCATTGGG CTGCGGAGGC AATGGCTTGG TCTTTTCTGC TGTAGACAAT 
GACTGTGACA AAAGAGTAGC CATCAAGAAA ATTGTCCTCA CCGATCCCCA GAGTGTCAAA 
CATGCTCTCC GTGAAATCAA AATTATTCGA AGACTTGACC ACGATAACAT TGTGAAAGTG 
TTTGAAATTC TTGGTCCCAG TGGAAGCCAG TTAACAGACG ATGTGGGCTC TCTCACGGAG 
CTGAATAGCG TCTACATTGT TCAGGAGTAT ATGGAGACAG ACTTGGCGAA TGTGCTGGAG 
CAGGGCCCTT TACTGGAAGA GCATGCCAGG CTTTTCATGT ATCAGCTGCT ACGTGGGCTC 
AAATATATCC ATTCTGCAAA CGTACTGCAC AGAGATCTCA AGCCAGCTAA TCTTTTCATT 
AACACTGAAG ACTTGGTGCT GAAGATAGGT GACTTTGGCC TGGCACGGAT CATGGATCCT 
CATTATTCCC ATAAGGGTCA TCTTTCTGAA GGATTGGTTA CCAAATGGTA CAGATCTCCA 
CGGCTTTTAC TTTCTCCTAA TAATTACACT AAAGCCATTG ACATGTGGGC TGCAGGCTGC 
ATCTTTGCTG AGATGCTGAC TGGTAAAACC CTCTTTGCAG GTGCACATGA ACTTGAACAG 
ATGCAGCTGA TCCTCGACTC CATCCCTGTT GTGCACGAGG AGGATCGGCA GGAGCTTCTC 
AGCGTGATTC CAGTTTACAT TAGAAACGAC ATGACTGAGC CACACAGACC GCTCACTCAG 
CTGCTGCCGG GGATCAGCCG AGAAGCACTG GATTTCCTGG AGCAGATTCT GACTTTCAGC 
CCCATGGACC GGCTGACAGC TGAGGAAGCC CTTTCCCATC CTTACATGAG CATCTACTCC 
TTCCCGACGG ATGAGCCCAT CTCAAGCCAC CCTTTCCACA TAGAGGACGA AGTGGACGAC 
ATTTTGCTTA TGGATGAAAC ACACAGTCAC ATTTATAACT GGGAAAGGTA CCACGATTGT 
CAGTTCTCGG AGCATGACTG GCCTATTCAT AACAACTTTG ATATCGATGA GGTGCAGCTT 
GACCCAAGAG CTCTGTCTGA CGTCACCGAT GAAGAAGAAG TCCAAGTTGA TCCTCGAAAA 
TACTTGGATG GAGACCGAGA GAAGTATCTA GAGGATCCCG CCTTCGACAC CAGCTACTCT 
GCTGAACCCT GCTGGCAGTA CCCAGATCAC CACGAGAACA AGTACTGCGA TCTGGAGTGT 
AGCCACACCT GTAACTACAA AACAAGATCA TCACCATACT TAGATAACCT GGTGTGGAGG 
GAGAGCGAGG TTAACCATTA CTATGAGCCC AAGCTTATTA TAGATCTTTC CAACTGGAAA 
GAGCAAAGTA AAGAAAAATC CGATAAGAGA GGCAAGTCCA AGTGTGAGAG GAACGGGTTG 
GTCAAGGCGC AGATCGCGCT AGAGGAAGCA TCCCAGCAGC TGGCTGAGAG GGAGAGGGGC 
CAAGGCTTCG ACTTTGACTC CTTCATCGCG GGGACCATTC AGCTCAGTGC CCAGCATCAG 
TCTGCTGACG TAGTTGACAA GTTAAACGAC TTGAATAGCT CAGTGTCCCA GCTAGAATTG 
AAAAGCCTGA TATCCAAGTC AGTCAGCCGA GAAAAGCAAG AAAAGGGAAG GGCTAACCTG 
GCCCAGCTGG GAGCCTTGTA CCAGTCCTCC TGGGACAGCC AGTTTGTGAG TGGCGGGGAG 
GAGTGCTTCC TCATCAGTCA GTTTTGTTGT GAGGTCAGGA AGGACGAGCA TGCGGAGAAG 
GAGAACACCT ACACCAGCTA TTTGGACAAG TTTTTTAGCA GGAAGGAGGA TTCCGAAATG 
CTAGAAACTG AGCCAGTGGA GGAAGGGAAG CGTGGGGAGA GAGGCCGTGA GGCAGGGCTT 
CTGAGCGGCG GTGGGGAGTT CCTCCTGAGC AAGCAGCTGG AGTCCATAGG CACCCCGCAG 
TTCCACAGCC CAGTGGGGTC CCCACTCAAG TCCATCCAGG CCACCTTGAC ACCTTCCGCT 
ATGAAATCTT CCCCTCAAAT CCCTCACAAG ACATACAGCA GCATTCTGAA ACATCTGAAC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The atypical MAPK ERK3 controls positive selection of thymocytes.
Immunology145(1)161-9(2015 May)
Sirois J,Daudelin JF,Boulet S,Marquis M,Meloche S,Labrecque N

The catalytic activity of the mitogen-activated protein kinase extracellular signal-regulated kinase 3 is required to sustain CD4+ CD8+ thymocyte survival.
Molecular and cellular biology34(18)3374-87(2014 Sep)
Marquis M,Daudelin JF,Boulet S,Sirois J,Crain K,Mathien S,Turgeon B,Rousseau J,Meloche S,Labrecque N

The non-classical MAP kinase ERK3 controls T cell activation.
PloS one9(1)e86681(2014)
Marquis M,Boulet S,Mathien S,Rousseau J,Th?bault P,Daudelin JF,Rooney J,Turgeon B,Beauchamp C,Meloche S,Labrecque N

The extracellular signal-regulated kinase 3 (mitogen-activated protein kinase 6 [MAPK6])-MAPK-activated protein kinase 5 signaling complex regulates septin function and dendrite morphology.
Molecular and cellular biology32(13)2467-78(2012 Jul)
Brand F,Schumacher S,Kant S,Menon MB,Simon R,Turgeon B,Britsch S,Meloche S,Gaestel M,Kotlyarov A

ERKs induce expression of the transcriptional repressor Blimp-1 and subsequent plasma cell differentiation.
Science signaling4(169)ra25(2011 Apr)
Yasuda T,Kometani K,Takahashi N,Imai Y,Aiba Y,Kurosaki T

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Mapk6 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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