Catsper4 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Catsper4
Entrez Gene ID	329954
Full Name	cation channel, sperm associated 4
Synonyms	4933412L05
General protein information	Preferred Names cation channel, sperm associated 4 Names cation channel sperm-associated protein 4 cation channel of sperm 4 channel, sperm associated 4
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 4 Map Location: 4\|4 D3

mRNA and Protein(s)

mRNA	Protein	Name
XM_006538954.3	XP_006539017.1	cation channel sperm-associated protein 4 isoform X1
NM_177866.4	NP_808534.1	cation channel sperm-associated protein 4 isoform 1
XM_011250280.2	XP_011248582.1	cation channel sperm-associated protein 4 isoform X1
NM_001130030.1	NP_001123502.1	cation channel sperm-associated protein 4 isoform 2

Pathways from BioSystems

Homologies

	CATSPER4	XP_001108634.1
Canis lupus familiaris (dog)	CATSPER4	XP_005617817.1
Homo sapiens (human)	CATSPER4	NP_937770.1
Bos taurus (cattle)	CATSPER4	XP_002685811.2
Pan troglodytes (chimpanzee)	CATSPER4	XP_001139244.1
Rattus norvegicus (Norway rat)	Catsper4	XP_342942.5
Mus musculus (house mouse)	Catsper4	NP_808534.1

Gene Ontology
Bibliography

Related articles in PubMed

A novel gene required for male fertility and functional CATSPER channel formation in spermatozoa.
Chung JJ, Navarro B, Krapivinsky G, Krapivinsky L, Clapham DE
Nature communications2153(2011 Jan)

CatSper genes expression, semen characteristics and histology of testes in the contusive spinal cord-injured mice model.
Rezaian J, Movahedin M, Mowla SJ
Spinal cord47(1)76-81(2009 Jan)

CATSPER channel-mediated Ca2+ entry into mouse sperm triggers a tail-to-head propagation.
Xia J, Reigada D, Mitchell CH, Ren D
Biology of reproduction77(3)551-9(2007 Sep)

Catsper3 and Catsper4 are essential for sperm hyperactivated motility and male fertility in the mouse.
Jin J, Jin N, Zheng H, Ro S, Tafolla D, Sanders KM, Yan W
Biology of reproduction77(1)37-44(2007 Jul)

All four CatSper ion channel proteins are required for male fertility and sperm cell hyperactivated motility.
Qi H, Moran MM, Navarro B, Chong JA, Krapivinsky G, Krapivinsky L, Kirichok Y, Ramsey IS, Quill TA, Clapham DE
Proceedings of the National Academy of Sciences of the United States of America104(4)1219-23(2007 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data show that spinal cord injury doesn't significantly change the expression of CatSpers 4.
Title: CatSper genes expression, semen characteristics and histology of testes in the contusive spinal cord-injured mice model.

Catsper3 and Catsper4 knockout male mice are completely infertile due to a quick loss of motility and a lack of hyperactivated motility under capacitating conditions.
Title: Catsper3 and Catsper4 are essential for sperm hyperactivated motility and male fertility in the mouse.

CATSPER4 is a cation-channel protein and has role in acrosome reaction and male fertility
Title: Catsper3 and catsper4 encode two cation channel-like proteins exclusively expressed in the testis.

Catsper4 has a single channel-forming domain, a pore-loop with the consensus sequence TxDxW, & a coiled-coil protein-protein interaction domain in the C-terminal tail. CatSpers 1,2,3 & 4 may interact directly or indirectly to form a functional tetramer.
Title: Identification of human and mouse CatSper3 and CatSper4 genes: characterisation of a common interaction domain and evidence for expression in testis.

The following Catsper4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Catsper4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu22567	NM_001130030.1 Latest version!	Mus musculus cation channel, sperm associated 4 (Catsper4), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00
OMu22919	NM_177866.4 Latest version!	Mus musculus cation channel, sperm associated 4 (Catsper4), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00
OMu34272	XM_006538954.3 Latest version!	Mus musculus cation channel, sperm associated 4 (Catsper4), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OMu74845	XM_011250280.2 Latest version!	Mus musculus cation channel, sperm associated 4 (Catsper4), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Catsper4 ( NM_001130030.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001123502.1 Mus musculus cation channel, sperm associated 4 (Catsper4), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu22567
Clone ID Related Accession (Same CDS sequence)	NM_001130030.1
Accession Version	NM_001130030.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1110bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Mus musculus(house mouse)
Product	cation channel sperm-associated protein 4 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY104668.1, EU781511.1, AK077145.1 and CR513858.1. Transcript Variant: This variant (2) is missing 2 contiguous internal coding exons compared to variant 1, however, it maintains the reading frame, and encodes a shorter isoform (2) that is lacking a 73 aa internal segment compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: EU781511.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849384 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCTGAAA AACACAAGTG GTGGCAGCAG GTGGAGAACA TCGACATCAC ACACCTGGGC 
CCTAAGAGAA AAGCCTATGA ACTCCTGGGT CGGCATGAGG AGCAAGTGCT CATCAACCGC 
AGAGATGTCA TGGAGAAGAA GGATGCCTGG GATGTACAGG AATTCATCAC TCAAATGTAT 
ATCAAGCAGT TGCTCCGCCA TCCGGCCTTC CAGCTGCTGC TGGCCTTTCT GCTGCTGTCC 
AACGCTATCA CCATTGCCCT TCGCACCAAC TCTTATCTCG GTCAGAAACA TTACGAGCTA 
TTCTCGACCA TAGATGACAT TGTGTTGACG ATCCTTATCT GCGAGGTTCT GCTTGGTTGG 
CTTAACGGCT TCTGGATTTT CTGGAAGGTA TTCTCTGTGT TTGGGGTCAC GCTCTTCGGT 
GCATTTGTGC CCAAGCATTT CCAGAACATG GGGGTTGCCC TGTACACGCT CTTCATCTGC 
ATCACTCAGG ATGGATGGCT GGACATCTAC ACTGACTTCC AGATGGATGA AAGAGAGTAC 
GCGATGGAGG TCGGGGGCGC CATCTACTTT GCCGTCTTTA TCACCCTCGG TGCCTTCATT 
GGTCTCAACT TGTTCGTCGT CGTGGTGACC ACAAACCTGG AACAAATGAT GAAGACCGGC 
GAGGAAGAGG GACACCTGAA CATAAAGTTT ACTGAGACAG AAGAGGATGA GGACTGGACC 
GACGAGCTGC CACTGGTGCA TTGTACAGAG GCCCGCAAGG ATACTTCCAC TGTCCCCAAG 
GAACCACTGG TTGGGGGCCC CCTGAGTAAC CTCACAGAAA AGACCTGCGA TAACTTCTGC 
TTGGTGCTTG AAGCAATACA GGAGAACTTG ATGGAGTACA AAGAGATCCG AGAGGAACTC 
AACATGATCG TGGAGGAAGT GTCCTCCATC CGGTTCAACC AGGAGCAGCA AAATGTGATC 
CTACACAAGT ATACCTCCAA AAGCGCCACC TTCCTAAGCG AGCCCCCAGA AGGGGCTAAC 
AAGCAAGACT TGATCACTGC GCTGGTCAGC AGGGAAAAGG TGTCTGATTC TAACATAAAC 
ATGGTTAACA AACACAAGTT CAGCCACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001123502.1
CDS	47..1156
Translation	MSEKHKWWQQVENIDITHLGPKRKAYELLGRHEEQVLINRRDVMEKKDAWDVQEFITQMYIKQLLRHPAFQLLLAFLLLSNAITIALRTNSYLGQKHYELFSTIDDIVLTILICEVLLGWLNGFWIFWKVFSVFGVTLFGAFVPKHFQNMGVALYTLFICITQDGWLDIYTDFQMDEREYAMEVGGAIYFAVFITLGAFIGLNLFVVVVTTNLEQMMKTGEEEGHLNIKFTETEEDEDWTDELPLVHCTEARKDTSTVPKEPLVGGPLSNLTEKTCDNFCLVLEAIQENLMEYKEIREELNMIVEEVSSIRFNQEQQNVILHKYTSKSATFLSEPPEGANKQDLITALVSREKVSDSNINMVNKHKFSH

Target ORF information:

RefSeq Version	NM_001130030.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus cation channel, sperm associated 4 (Catsper4), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001130030.1

ORF Insert Sequence:

ATGTCTGAAA AACACAAGTG GTGGCAGCAG GTGGAGAACA TCGACATCAC ACACCTGGGC 
CCTAAGAGAA AAGCCTATGA ACTCCTGGGT CGGCATGAGG AGCAAGTGCT CATCAACCGC 
AGAGATGTCA TGGAGAAGAA GGATGCCTGG GATGTACAGG AATTCATCAC TCAAATGTAT 
ATCAAGCAGT TGCTCCGCCA TCCGGCCTTC CAGCTGCTGC TGGCCTTTCT GCTGCTGTCC 
AACGCTATCA CCATTGCCCT TCGCACCAAC TCTTATCTCG GTCAGAAACA TTACGAGCTA 
TTCTCGACCA TAGATGACAT TGTGTTGACG ATCCTTATCT GCGAGGTTCT GCTTGGTTGG 
CTTAACGGCT TCTGGATTTT CTGGAAGGTA TTCTCTGTGT TTGGGGTCAC GCTCTTCGGT 
GCATTTGTGC CCAAGCATTT CCAGAACATG GGGGTTGCCC TGTACACGCT CTTCATCTGC 
ATCACTCAGG ATGGATGGCT GGACATCTAC ACTGACTTCC AGATGGATGA AAGAGAGTAC 
GCGATGGAGG TCGGGGGCGC CATCTACTTT GCCGTCTTTA TCACCCTCGG TGCCTTCATT 
GGTCTCAACT TGTTCGTCGT CGTGGTGACC ACAAACCTGG AACAAATGAT GAAGACCGGC 
GAGGAAGAGG GACACCTGAA CATAAAGTTT ACTGAGACAG AAGAGGATGA GGACTGGACC 
GACGAGCTGC CACTGGTGCA TTGTACAGAG GCCCGCAAGG ATACTTCCAC TGTCCCCAAG 
GAACCACTGG TTGGGGGCCC CCTGAGTAAC CTCACAGAAA AGACCTGCGA TAACTTCTGC 
TTGGTGCTTG AAGCAATACA GGAGAACTTG ATGGAGTACA AAGAGATCCG AGAGGAACTC 
AACATGATCG TGGAGGAAGT GTCCTCCATC CGGTTCAACC AGGAGCAGCA AAATGTGATC 
CTACACAAGT ATACCTCCAA AAGCGCCACC TTCCTAAGCG AGCCCCCAGA AGGGGCTAAC 
AAGCAAGACT TGATCACTGC GCTGGTCAGC AGGGAAAAGG TGTCTGATTC TAACATAAAC 
ATGGTTAACA AACACAAGTT CAGCCACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Catsper4 ( NM_177866.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_808534.1 Mus musculus cation channel, sperm associated 4 (Catsper4), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu22919
Clone ID Related Accession (Same CDS sequence)	NM_177866.4
Accession Version	NM_177866.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1329bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Mus musculus(house mouse)
Product	cation channel sperm-associated protein 4 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY104668.1, AK077145.1 and CR513858.1. On Jul 11, 2008 this sequence version replaced NM_177866.3. Transcript Variant: This variant (1) encodes the longer isoform (1). ##Evidence-Data-START## Transcript exon combination :: AK077145.1, BC108974.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849384 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCTGAAA AACACAAGTG GTGGCAGCAG GTGGAGAACA TCGACATCAC ACACCTGGGC 
CCTAAGAGAA AAGCCTATGA ACTCCTGGGT CGGCATGAGG AGCAAGTGCT CATCAACCGC 
AGAGATGTCA TGGAGAAGAA GGATGCCTGG GATGTACAGG AATTCATCAC TCAAATGTAT 
ATCAAGCAGT TGCTCCGCCA TCCGGCCTTC CAGCTGCTGC TGGCCTTTCT GCTGCTGTCC 
AACGCTATCA CCATTGCCCT TCGCACCAAC TCTTATCTCG GTCAGAAACA TTACGAGCTA 
TTCTCGACCA TAGATGACAT TGTGTTGACG ATCCTTATCT GCGAGGTTCT GCTTGGTTGG 
CTTAACGGCT TCTGGATTTT CTGGAAGGAT GGCTGGAATA TCCTCAACTT CGCAATTGTC 
TTTATCTTGT TTATGGGGTT CTTCATAAAA CAACTTGACA TGGTTGCCAT CACCTACCCT 
CTCAGGGTGC TCCGGCTGGT GCATGTGTGT ATGGCGGTGG AACCCCTGGC CAGAATCATC 
AAGGTTATCC TGCAGTCGAT GCCAGACTTG GCTAATGTCA TGGCTCTCAT CCTCTTCTTC 
ATGCTGGTAT TCTCTGTGTT TGGGGTCACG CTCTTCGGTG CATTTGTGCC CAAGCATTTC 
CAGAACATGG GGGTTGCCCT GTACACGCTC TTCATCTGCA TCACTCAGGA TGGATGGCTG 
GACATCTACA CTGACTTCCA GATGGATGAA AGAGAGTACG CGATGGAGGT CGGGGGCGCC 
ATCTACTTTG CCGTCTTTAT CACCCTCGGT GCCTTCATTG GTCTCAACTT GTTCGTCGTC 
GTGGTGACCA CAAACCTGGA ACAAATGATG AAGACCGGCG AGGAAGAGGG ACACCTGAAC 
ATAAAGTTTA CTGAGACAGA AGAGGATGAG GACTGGACCG ACGAGCTGCC ACTGGTGCAT 
TGTACAGAGG CCCGCAAGGA TACTTCCACT GTCCCCAAGG AACCACTGGT TGGGGGCCCC 
CTGAGTAACC TCACAGAAAA GACCTGCGAT AACTTCTGCT TGGTGCTTGA AGCAATACAG 
GAGAACTTGA TGGAGTACAA AGAGATCCGA GAGGAACTCA ACATGATCGT GGAGGAAGTG 
TCCTCCATCC GGTTCAACCA GGAGCAGCAA AATGTGATCC TACACAAGTA TACCTCCAAA 
AGCGCCACCT TCCTAAGCGA GCCCCCAGAA GGGGCTAACA AGCAAGACTT GATCACTGCG 
CTGGTCAGCA GGGAAAAGGT GTCTGATTCT AACATAAACA TGGTTAACAA ACACAAGTTC 
AGCCACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_808534.1
CDS	47..1375
Translation	MSEKHKWWQQVENIDITHLGPKRKAYELLGRHEEQVLINRRDVMEKKDAWDVQEFITQMYIKQLLRHPAFQLLLAFLLLSNAITIALRTNSYLGQKHYELFSTIDDIVLTILICEVLLGWLNGFWIFWKDGWNILNFAIVFILFMGFFIKQLDMVAITYPLRVLRLVHVCMAVEPLARIIKVILQSMPDLANVMALILFFMLVFSVFGVTLFGAFVPKHFQNMGVALYTLFICITQDGWLDIYTDFQMDEREYAMEVGGAIYFAVFITLGAFIGLNLFVVVVTTNLEQMMKTGEEEGHLNIKFTETEEDEDWTDELPLVHCTEARKDTSTVPKEPLVGGPLSNLTEKTCDNFCLVLEAIQENLMEYKEIREELNMIVEEVSSIRFNQEQQNVILHKYTSKSATFLSEPPEGANKQDLITALVSREKVSDSNINMVNKHKFSH

Target ORF information:

RefSeq Version	NM_177866.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus cation channel, sperm associated 4 (Catsper4), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_177866.4

ORF Insert Sequence:

ATGTCTGAAA AACACAAGTG GTGGCAGCAG GTGGAGAACA TCGACATCAC ACACCTGGGC 
CCTAAGAGAA AAGCCTATGA ACTCCTGGGT CGGCATGAGG AGCAAGTGCT CATCAACCGC 
AGAGATGTCA TGGAGAAGAA GGATGCCTGG GATGTACAGG AATTCATCAC TCAAATGTAT 
ATCAAGCAGT TGCTCCGCCA TCCGGCCTTC CAGCTGCTGC TGGCCTTTCT GCTGCTGTCC 
AACGCTATCA CCATTGCCCT TCGCACCAAC TCTTATCTCG GTCAGAAACA TTACGAGCTA 
TTCTCGACCA TAGATGACAT TGTGTTGACG ATCCTTATCT GCGAGGTTCT GCTTGGTTGG 
CTTAACGGCT TCTGGATTTT CTGGAAGGAT GGCTGGAATA TCCTCAACTT CGCAATTGTC 
TTTATCTTGT TTATGGGGTT CTTCATAAAA CAACTTGACA TGGTTGCCAT CACCTACCCT 
CTCAGGGTGC TCCGGCTGGT GCATGTGTGT ATGGCGGTGG AACCCCTGGC CAGAATCATC 
AAGGTTATCC TGCAGTCGAT GCCAGACTTG GCTAATGTCA TGGCTCTCAT CCTCTTCTTC 
ATGCTGGTAT TCTCTGTGTT TGGGGTCACG CTCTTCGGTG CATTTGTGCC CAAGCATTTC 
CAGAACATGG GGGTTGCCCT GTACACGCTC TTCATCTGCA TCACTCAGGA TGGATGGCTG 
GACATCTACA CTGACTTCCA GATGGATGAA AGAGAGTACG CGATGGAGGT CGGGGGCGCC 
ATCTACTTTG CCGTCTTTAT CACCCTCGGT GCCTTCATTG GTCTCAACTT GTTCGTCGTC 
GTGGTGACCA CAAACCTGGA ACAAATGATG AAGACCGGCG AGGAAGAGGG ACACCTGAAC 
ATAAAGTTTA CTGAGACAGA AGAGGATGAG GACTGGACCG ACGAGCTGCC ACTGGTGCAT 
TGTACAGAGG CCCGCAAGGA TACTTCCACT GTCCCCAAGG AACCACTGGT TGGGGGCCCC 
CTGAGTAACC TCACAGAAAA GACCTGCGAT AACTTCTGCT TGGTGCTTGA AGCAATACAG 
GAGAACTTGA TGGAGTACAA AGAGATCCGA GAGGAACTCA ACATGATCGT GGAGGAAGTG 
TCCTCCATCC GGTTCAACCA GGAGCAGCAA AATGTGATCC TACACAAGTA TACCTCCAAA 
AGCGCCACCT TCCTAAGCGA GCCCCCAGAA GGGGCTAACA AGCAAGACTT GATCACTGCG 
CTGGTCAGCA GGGAAAAGGT GTCTGATTCT AACATAAACA TGGTTAACAA ACACAAGTTC 
AGCCACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Catsper4 ( XM_006538954.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006539017.1 Mus musculus cation channel, sperm associated 4 (Catsper4), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu34272
Clone ID Related Accession (Same CDS sequence)	XM_006538954.3
Accession Version	XM_006538954.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1020bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	cation channel sperm-associated protein 4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000070.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006538954.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCTGAAA AACACAAGTG GTGGCAGCAG GTGGAGAACA TCGACATCAC ACACCTGGGC 
CCTAAGAGAA AAGCCTATGA ACTCCTGGGT CGGCATGAGG AGCAAGTGCT CATCAACCGC 
AGAGATGTCA TGGAGAAGAA GGATGCCTGG GATGTACAGG AATTCATCAC TCAAATGTAT 
ATCAAGCAGT TGCTCCGCCA TCCGGCCTTC CAGCTGCTGC TGGCCTTTCT GCTGCTGTCC 
AACGCTATCA CCATTGCCCT TCGCACCAAC TCTTATCTCG GTCAGAAACA TTACGAGCTA 
TTCTCGACCA TAGATGACAT TGTGTTGACG ATCCTTATCT GCGAGGTTCT GCTTGGTTGG 
CTTAACGGCT TCTGGATTTT CTGGAAGGAT GGCTGGAATA TCCTCAACTT CGCAATTGTC 
TTTATCTTGT TTATGGGGTT CTTCATAAAA CAACTTGACA TGGTTGCCAT CACCTACCCT 
CTCAGGGTGC TCCGGCTGGT GCATGTGTGT ATGGCGGTGG AACCCCTGGC CAGAATCATC 
AAGGTTATCC TGCAGTCGAT GCCAGACTTG GCTAATGTCA TGGCTCTCAT CCTCTTCTTC 
ATGCTGGTAT TCTCTGTGTT TGGGGTCACG CTCTTCGGTG CATTTGTGCC CAAGCATTTC 
CAGAACATGG GGGTTGCCCT GTACACGCTC TTCATCTGCA TCACTCAGGA TGGATGGCTG 
GACATCTACA CTGACTTCCA GATGGATGAA AGAGAGTACG CGATGGAGGT CGGGGGCGCC 
ATCTACTTTG CCGTCTTTAT CACCCTCGGT GCCTTCATTG GTCTCAACTT GTTCGTCGTC 
GTGGTGACCA CAAACCTGGA ACAAATGATG AAGACCGGCG AGGAAGAGGG ACACCTGAAC 
ATAAAGTTTA CTGAGAAGAG GATGAGGACT GGACCGACGA GCTGCCACTG GTGCATTGTA 
CAGAGGCCCG CAAGGATACT TCCACTGTCC CCAAGGAACC ACTGGTTGGG GGCCCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006539017.1
CDS	94..1113
Translation	MSEKHKWWQQVENIDITHLGPKRKAYELLGRHEEQVLINRRDVMEKKDAWDVQEFITQMYIKQLLRHPAFQLLLAFLLLSNAITIALRTNSYLGQKHYELFSTIDDIVLTILICEVLLGWLNGFWIFWKDGWNILNFAIVFILFMGFFIKQLDMVAITYPLRVLRLVHVCMAVEPLARIIKVILQSMPDLANVMALILFFMLVFSVFGVTLFGAFVPKHFQNMGVALYTLFICITQDGWLDIYTDFQMDEREYAMEVGGAIYFAVFITLGAFIGLNLFVVVVTTNLEQMMKTGEEEGHLNIKFTEKRMRTGPTSCHWCIVQRPARILPLSPRNHWLGAP

Target ORF information:

RefSeq Version	XM_006538954.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus cation channel, sperm associated 4 (Catsper4), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006538954.3

ORF Insert Sequence:

ATGTCTGAAA AACACAAGTG GTGGCAGCAG GTGGAGAACA TCGACATCAC ACACCTGGGC 
CCTAAGAGAA AAGCCTATGA ACTCCTGGGT CGGCATGAGG AGCAAGTGCT CATCAACCGC 
AGAGATGTCA TGGAGAAGAA GGATGCCTGG GATGTACAGG AATTCATCAC TCAAATGTAT 
ATCAAGCAGT TGCTCCGCCA TCCGGCCTTC CAGCTGCTGC TGGCCTTTCT GCTGCTGTCC 
AACGCTATCA CCATTGCCCT TCGCACCAAC TCTTATCTCG GTCAGAAACA TTACGAGCTA 
TTCTCGACCA TAGATGACAT TGTGTTGACG ATCCTTATCT GCGAGGTTCT GCTTGGTTGG 
CTTAACGGCT TCTGGATTTT CTGGAAGGAT GGCTGGAATA TCCTCAACTT CGCAATTGTC 
TTTATCTTGT TTATGGGGTT CTTCATAAAA CAACTTGACA TGGTTGCCAT CACCTACCCT 
CTCAGGGTGC TCCGGCTGGT GCATGTGTGT ATGGCGGTGG AACCCCTGGC CAGAATCATC 
AAGGTTATCC TGCAGTCGAT GCCAGACTTG GCTAATGTCA TGGCTCTCAT CCTCTTCTTC 
ATGCTGGTAT TCTCTGTGTT TGGGGTCACG CTCTTCGGTG CATTTGTGCC CAAGCATTTC 
CAGAACATGG GGGTTGCCCT GTACACGCTC TTCATCTGCA TCACTCAGGA TGGATGGCTG 
GACATCTACA CTGACTTCCA GATGGATGAA AGAGAGTACG CGATGGAGGT CGGGGGCGCC 
ATCTACTTTG CCGTCTTTAT CACCCTCGGT GCCTTCATTG GTCTCAACTT GTTCGTCGTC 
GTGGTGACCA CAAACCTGGA ACAAATGATG AAGACCGGCG AGGAAGAGGG ACACCTGAAC 
ATAAAGTTTA CTGAGAAGAG GATGAGGACT GGACCGACGA GCTGCCACTG GTGCATTGTA 
CAGAGGCCCG CAAGGATACT TCCACTGTCC CCAAGGAACC ACTGGTTGGG GGCCCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Catsper4 ( XM_011250280.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011248582.1 Mus musculus cation channel, sperm associated 4 (Catsper4), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu74845
Clone ID Related Accession (Same CDS sequence)	XM_011250280.2
Accession Version	XM_011250280.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 822bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	cation channel sperm-associated protein 4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000070.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_011250280.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCTGAAA AACACAAGTG GTGGCAGCAG GTGGAGAACA TCGACATCAC ACACCTGGGC 
CCTAAGAGAA AAGCCTATGA ACTCCTGGGT CGGCATGAGG AGCAAGTGCT CATCAACCGC 
AGAGATGTCA TGGAGAAGAA GGATGCCTGG GATGTACAGG AATTCATCAC TCAAATGTAT 
ATCAAGCAGT TGCTCCGCCA TCCGGCCTTC CAGCTGCTGC TGGCCTTTCT GCTGCTGTCC 
AACGCTATCA CCATTGCCCT TCGCACCAAC TCTTATCTCG GTCAGAAACA TTACGAGCTA 
TTCTCGACCA TAGATGACAT TGTGTTGACG ATCCTTATCT GCGAGGTTCT GCTTGGTTGG 
CTTAACGGCT TCTGGATTTT CTGGAAGGAT GGCTGGAATA TCCTCAACTT CGCAATTGTC 
TTTATCTTGT TTATGGGGTT CTTCATAAAA CAACTTGACA TGGTTGCCAT CACCTACCCT 
CTCAGGGTGC TCCGGCTGGT GCATGTGTGT ATGGCGGTGG AACCCCTGGC CAGAATCATC 
AAGGTTATCC TGCAGTCGAT GCCAGACTTG GCTAATGTCA TGGCTCTCAT CCTCTTCTTC 
ATGCTGGTAT TCTCTGTGTT TGGGGTCACG CTCTTCGGTG CATTTGTGCC CAAGCATTTC 
CAGAACATGG GGGTTGCCCT GTACACGCTC TTCATCTGCA TCACTCAGGA TGGATGGCTG 
GACATCTACA CTGACTTCCA TGAGATAGTA CAATACAGTA CTGACTATGT CATCGGGTGG 
CGTGAGGATC AGTCTAGAAA GATCTGTAGA ACTCTTCTAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011248582.1
CDS	95..916
Translation	MSEKHKWWQQVENIDITHLGPKRKAYELLGRHEEQVLINRRDVMEKKDAWDVQEFITQMYIKQLLRHPAFQLLLAFLLLSNAITIALRTNSYLGQKHYELFSTIDDIVLTILICEVLLGWLNGFWIFWKDGWNILNFAIVFILFMGFFIKQLDMVAITYPLRVLRLVHVCMAVEPLARIIKVILQSMPDLANVMALILFFMLVFSVFGVTLFGAFVPKHFQNMGVALYTLFICITQDGWLDIYTDFHEIVQYSTDYVIGWREDQSRKICRTLL

Target ORF information:

RefSeq Version	XM_011250280.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus cation channel, sperm associated 4 (Catsper4), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011250280.2

ORF Insert Sequence:

ATGTCTGAAA AACACAAGTG GTGGCAGCAG GTGGAGAACA TCGACATCAC ACACCTGGGC 
CCTAAGAGAA AAGCCTATGA ACTCCTGGGT CGGCATGAGG AGCAAGTGCT CATCAACCGC 
AGAGATGTCA TGGAGAAGAA GGATGCCTGG GATGTACAGG AATTCATCAC TCAAATGTAT 
ATCAAGCAGT TGCTCCGCCA TCCGGCCTTC CAGCTGCTGC TGGCCTTTCT GCTGCTGTCC 
AACGCTATCA CCATTGCCCT TCGCACCAAC TCTTATCTCG GTCAGAAACA TTACGAGCTA 
TTCTCGACCA TAGATGACAT TGTGTTGACG ATCCTTATCT GCGAGGTTCT GCTTGGTTGG 
CTTAACGGCT TCTGGATTTT CTGGAAGGAT GGCTGGAATA TCCTCAACTT CGCAATTGTC 
TTTATCTTGT TTATGGGGTT CTTCATAAAA CAACTTGACA TGGTTGCCAT CACCTACCCT 
CTCAGGGTGC TCCGGCTGGT GCATGTGTGT ATGGCGGTGG AACCCCTGGC CAGAATCATC 
AAGGTTATCC TGCAGTCGAT GCCAGACTTG GCTAATGTCA TGGCTCTCAT CCTCTTCTTC 
ATGCTGGTAT TCTCTGTGTT TGGGGTCACG CTCTTCGGTG CATTTGTGCC CAAGCATTTC 
CAGAACATGG GGGTTGCCCT GTACACGCTC TTCATCTGCA TCACTCAGGA TGGATGGCTG 
GACATCTACA CTGACTTCCA TGAGATAGTA CAATACAGTA CTGACTATGT CATCGGGTGG 
CGTGAGGATC AGTCTAGAAA GATCTGTAGA ACTCTTCTAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A novel gene required for male fertility and functional CATSPER channel formation in spermatozoa.
Nature communications2153(2011 Jan)
Chung JJ,Navarro B,Krapivinsky G,Krapivinsky L,Clapham DE

CatSper genes expression, semen characteristics and histology of testes in the contusive spinal cord-injured mice model.
Spinal cord47(1)76-81(2009 Jan)
Rezaian J,Movahedin M,Mowla SJ

CATSPER channel-mediated Ca2+ entry into mouse sperm triggers a tail-to-head propagation.
Biology of reproduction77(3)551-9(2007 Sep)
Xia J,Reigada D,Mitchell CH,Ren D

Catsper3 and Catsper4 are essential for sperm hyperactivated motility and male fertility in the mouse.
Biology of reproduction77(1)37-44(2007 Jul)
Jin J,Jin N,Zheng H,Ro S,Tafolla D,Sanders KM,Yan W

All four CatSper ion channel proteins are required for male fertility and sperm cell hyperactivated motility.
Proceedings of the National Academy of Sciences of the United States of America104(4)1219-23(2007 Jan)
Qi H,Moran MM,Navarro B,Chong JA,Krapivinsky G,Krapivinsky L,Kirichok Y,Ramsey IS,Quill TA,Clapham DE

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Catsper4 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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