Mill1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Mill1
Entrez Gene ID	266815
Full Name	MHC I like leukocyte 1
Synonyms	5530400I18Rik
General protein information	Preferred Names MHC I like leukocyte 1 Names MHC I like leukocyte 1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 7 Map Location: 7 A3\|7 9.15 cM

mRNA and Protein(s)

mRNA	Protein	Name
XM_006540014.1	XP_006540077.1	MHC I like leukocyte 1 isoform X2
XM_006540013.2	XP_006540076.1	MHC I like leukocyte 1 isoform X1
XM_006540014.2	XP_006540077.1	MHC I like leukocyte 1 isoform X2
NM_153749.4	NP_715630.3	MHC I like leukocyte 1 precursor

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Mill1	NP_001011931.1
Mus musculus (house mouse)	Mill1	NP_715630.3

Gene Ontology
Bibliography

Related articles in PubMed

Reversal of epigenetic silencing of MHC class I chain-related protein A and B improves immune recognition of Merkel cell carcinoma.
Ritter C, Fan K, Paulson KG, Nghiem P, Schrama D, Becker JC
Scientific reports621678(2016 Feb)

Recognition of the ligand-type specificity of classical and non-classical MHC I proteins.
Mart?nez-Naves E, Lafuente EM, Reche PA
FEBS letters585(21)3478-84(2011 Nov)

A role for the MHC class I-like Mill molecules in nutrient metabolism and wound healing.
Rabinovich BA, Ketchem RR, Wolfson M, Goldstein L, Skelly M, Cosman D
Immunology and cell biology86(6)489-96(2008 Aug-Sep)

MHC class I-like MILL molecules are beta2-microglobulin-associated, GPI-anchored glycoproteins that do not require TAP for cell surface expression.
Kajikawa M, Baba T, Tomaru U, Watanabe Y, Koganei S, Tsuji-Kawahara S, Matsumoto N, Yamamoto K, Miyazawa M, Maenaka K, Ishizu A, Kasahara M
Journal of immunology (Baltimore, Md. : 1950)177(5)3108-15(2006 Sep)

Reconstructing an ancestral mammalian immune supercomplex from a marsupial major histocompatibility complex.
Belov K, Deakin JE, Papenfuss AT, Baker ML, Melman SD, Siddle HV, Gouin N, Goode DL, Sargeant TJ, Robinson MD, Wakefield MJ, Mahony S, Cross JG, Benos PV, Samollow PB, Speed TP, Graves JA, Miller RD
PLoS biology4(3)e46(2006 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Reversal of epigenetic silencing of MICA and MICB improves immune recognition and killing of Merkel cell carcinoma cells.
Title: Reversal of epigenetic silencing of MHC class I chain-related protein A and B improves immune recognition of Merkel cell carcinoma.

Our results suggest a role for the Mill proteins in cellular metabolism, with possible therapeutic significance.
Title: A role for the MHC class I-like Mill molecules in nutrient metabolism and wound healing.

two members of the mouse MILL family, MILL1 and MILL2, are GPI-anchored glycoproteins associated with beta2-microglobulin (beta2m)
Title: MHC class I-like MILL molecules are beta2-microglobulin-associated, GPI-anchored glycoproteins that do not require TAP for cell surface expression.

Mill1 and Mill2 genes are predicted to encode membrane glycoproteins with domain organization essentially similar to that of MHC class I heavy chains.
Title: A family of MHC class I-like genes located in the vicinity of the mouse leukocyte receptor complex.

The following Mill1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Mill1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu02988	NM_153749.4 Latest version!	Mus musculus MHC I like leukocyte 1 (Mill1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
OMu38276	XM_006540013.2 Latest version!	Mus musculus MHC I like leukocyte 1 (Mill1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
OMu38277	XM_006540014.2 Latest version!	Mus musculus MHC I like leukocyte 1 (Mill1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
View Old Accession Versions >>
OMu38277	XM_006540014.1	Mus musculus MHC I like leukocyte 1 (Mill1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Mill1 ( NM_153749.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_715630.3 Mus musculus MHC I like leukocyte 1 (Mill1), mRNA.

Price & Availability↑

CloneID	OMu02988
Clone ID Related Accession (Same CDS sequence)	NM_153749.4
Accession Version	NM_153749.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1188bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-27
Organism	Mus musculus(house mouse)
Product	MHC I like leukocyte 1 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK029010.1 and AC151983.3. On May 1, 2009 this sequence version replaced NM_153749.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AK029010.1, AK030695.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849383 [ECO:0000348] ##Evidence-Data-END##

ATGCTGCTGT CCAGGAACCT CAGAGCCCTA GCTGCGATCC ACCTGTGGAT AGTGTACCTG 
CTCCTGGAGG ATTTACTGGG CACCTGCGCA GAGGGTGACA ACCAAAGACT GGTGGCTTCT 
GCTCCCTACC AAGATATTGA GATCACTCTG GAGAAGCCTA GAGTACAGGC GGTAGCAGAA 
CCCCACACTC TGCGCTATGA CCTCATGGCC TTGTCTCTGG AGGTGCCTGG GTTGCCCCAG 
TTCCTGACCC TGAGATACTT CGATGATGAG CCCTTCCTGC CCTATAAGAA AAACAGCAGC 
ATAACAGACT CCCAGGAACC CAGGATCAAA GACCATCTGA GAGCTGAGAC CTGGGGAAGA 
GAGACTGACG ATCTTCAGGA AGAAGAGGAG CAACTCAAAG GGATGCTAGC TGAGATCACA 
GCCCAGAACG GCCAGAATAC GGATCTTCAC ATCCTCCAGG CAACCTTCGG CTGTGAGCTT 
CAAAGAAATG GAAGCACTAG AGGCTTCTGG AAACTGGGCT ATGATGGGCA GAACTTCCTC 
ACCTTTGACC AGAAGACTCT CACATGGACA GTGGATGGAC CTTCCACCCA GAAGAACAAG 
ACATTCTGGA AGACACGTGC ACCCAGAGCT GATCTAGTTA AGACATTCTT GGATGACATA 
TGTCCTGCTC AGCTCCAGAG ATACCTTGCT TCCTTGAGAA ATGGTCTGCT GAATACAGGT 
TTCCCAAAGG TGATTGTGAC CTTCAGGAAC TATCCAGTGG GCAGGATCAC ACTGACATGC 
CGGGCTTTTC GTCTGTATAC CCGTGTGGCC ACCCTGACCT GGCTTCAGTA TAGAAAGCCA 
GTACAGCAGA AAACCTTTGG ATCTGAAACT ATCCTGCCCA GTGGGGATGG CACCTACCAG 
GCCTGGGTGT CCATTCGGGT TCTTCCTGGA CAGGAATCAC AGTTCAGCTG CAACTTGAAG 
CACGGCAACC ACAATATCAA TGAACCTGCT GCCACTGAGG CCCCTGTCTA TGGTGCGAGA 
AGAGAACAAC CTCCCACCTC AGGTGTGGGA AGCAGGGTCG GGAAAAGCCT GTGGAGTGCA 
ATGACTACAG CTCTCGTGGT GATCTCCTGG ACATTAAGCC AGAAACTGAT GGGGCCTCTA 
CTCTGGTTCT GCTCTGGTGG CTTCTGCTCT TTTCTACAGT GTTGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_715630.3
CDS	264..1451
Translation	MLLSRNLRALAAIHLWIVYLLLEDLLGTCAEGDNQRLVASAPYQDIEITLEKPRVQAVAEPHTLRYDLMALSLEVPGLPQFLTLRYFDDEPFLPYKKNSSITDSQEPRIKDHLRAETWGRETDDLQEEEEQLKGMLAEITAQNGQNTDLHILQATFGCELQRNGSTRGFWKLGYDGQNFLTFDQKTLTWTVDGPSTQKNKTFWKTRAPRADLVKTFLDDICPAQLQRYLASLRNGLLNTGFPKVIVTFRNYPVGRITLTCRAFRLYTRVATLTWLQYRKPVQQKTFGSETILPSGDGTYQAWVSIRVLPGQESQFSCNLKHGNHNINEPAATEAPVYGARREQPPTSGVGSRVGKSLWSAMTTALVVISWTLSQKLMGPLLWFCSGGFCSFLQCW

Target ORF information:

RefSeq Version	NM_153749.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus MHC I like leukocyte 1 (Mill1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_153749.4

ORF Insert Sequence:

ATGCTGCTGT CCAGGAACCT CAGAGCCCTA GCTGCGATCC ACCTGTGGAT AGTGTACCTG 
CTCCTGGAGG ATTTACTGGG CACCTGCGCA GAGGGTGACA ACCAAAGACT GGTGGCTTCT 
GCTCCCTACC AAGATATTGA GATCACTCTG GAGAAGCCTA GAGTACAGGC GGTAGCAGAA 
CCCCACACTC TGCGCTATGA CCTCATGGCC TTGTCTCTGG AGGTGCCTGG GTTGCCCCAG 
TTCCTGACCC TGAGATACTT CGATGATGAG CCCTTCCTGC CCTATAAGAA AAACAGCAGC 
ATAACAGACT CCCAGGAACC CAGGATCAAA GACCATCTGA GAGCTGAGAC CTGGGGAAGA 
GAGACTGACG ATCTTCAGGA AGAAGAGGAG CAACTCAAAG GGATGCTAGC TGAGATCACA 
GCCCAGAACG GCCAGAATAC GGATCTTCAC ATCCTCCAGG CAACCTTCGG CTGTGAGCTT 
CAAAGAAATG GAAGCACTAG AGGCTTCTGG AAACTGGGCT ATGATGGGCA GAACTTCCTC 
ACCTTTGACC AGAAGACTCT CACATGGACA GTGGATGGAC CTTCCACCCA GAAGAACAAG 
ACATTCTGGA AGACACGTGC ACCCAGAGCT GATCTAGTTA AGACATTCTT GGATGACATA 
TGTCCTGCTC AGCTCCAGAG ATACCTTGCT TCCTTGAGAA ATGGTCTGCT GAATACAGGT 
TTCCCAAAGG TGATTGTGAC CTTCAGGAAC TATCCAGTGG GCAGGATCAC ACTGACATGC 
CGGGCTTTTC GTCTGTATAC CCGTGTGGCC ACCCTGACCT GGCTTCAGTA TAGAAAGCCA 
GTACAGCAGA AAACCTTTGG ATCTGAAACT ATCCTGCCCA GTGGGGATGG CACCTACCAG 
GCCTGGGTGT CCATTCGGGT TCTTCCTGGA CAGGAATCAC AGTTCAGCTG CAACTTGAAG 
CACGGCAACC ACAATATCAA TGAACCTGCT GCCACTGAGG CCCCTGTCTA TGGTGCGAGA 
AGAGAACAAC CTCCCACCTC AGGTGTGGGA AGCAGGGTCG GGAAAAGCCT GTGGAGTGCA 
ATGACTACAG CTCTCGTGGT GATCTCCTGG ACATTAAGCC AGAAACTGAT GGGGCCTCTA 
CTCTGGTTCT GCTCTGGTGG CTTCTGCTCT TTTCTACAGT GTTGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Mill1 ( XM_006540013.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006540076.1 Mus musculus MHC I like leukocyte 1 (Mill1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu38276
Clone ID Related Accession (Same CDS sequence)	XM_006540013.2
Accession Version	XM_006540013.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 984bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	MHC I like leukocyte 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 9, 2015 this sequence version replaced XM_006540013.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCTTGT CTCTGGAGGT GCCTGGGTTG CCCCAGTTCC TGACCCTGAG ATACTTCGAT 
GATGAGCCCT TCCTGCCCTA TAAGAAAAAC AGCAGCATAA CAGACTCCCA GGAACCCAGG 
ATCAAAGACC ATCTGAGAGC TGAGACCTGG GGAAGAGAGA CTGACGATCT TCAGGAAGAA 
GAGGAGCAAC TCAAAGGGAT GCTAGCTGAG ATCACAGCCC AGAACGGCCA GAATACGGAT 
CTTCACATCC TCCAGGCAAC CTTCGGCTGT GAGCTTCAAA GAAATGGAAG CACTAGAGGC 
TTCTGGAAAC TGGGCTATGA TGGGCAGAAC TTCCTCACCT TTGACCAGAA GACTCTCACA 
TGGACAGTGG ATGGACCTTC CACCCAGAAG AACAAGACAT TCTGGAAGAC ACGTGCACCC 
AGAGCTGATC TAGTTAAGAC ATTCTTGGAT GACATATGTC CTGCTCAGCT CCAGAGATAC 
CTTGCTTCCT TGAGAAATGG TCTGCTGAAT ACAGGTTTCC CAAAGGTGAT TGTGACCTTC 
AGGAACTATC CAGTGGGCAG GATCACACTG ACATGCCGGG CTTTTCGTCT GTATACCCGT 
GTGGCCACCC TGACCTGGCT TCAGTATAGA AAGCCAGTAC AGCAGAAAAC CTTTGGATCT 
GAAACTATCC TGCCCAGTGG GGATGGCACC TACCAGGCCT GGGTGTCCAT TCGGGTTCTT 
CCTGGACAGG AATCACAGTT CAGCTGCAAC TTGAAGCACG GCAACCACAA TATCAATGAA 
CCTGCTGCCA CTGAGGCCCC TGTCTATGGT GCGAGAAGAG AACAACCTCC CACCTCAGGT 
GTGGGAAGCA GGGTCGGGAA AAGCCTGTGG AGTGCAATGA CTACAGCTCT CGTGGTGATC 
TCCTGGACAT TAAGCCAGAA ACTGATGGGG CCTCTACTCT GGTTCTGCTC TGGTGGCTTC 
TGCTCTTTTC TACAGTGTTG GTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006540076.1
CDS	569..1552
Translation	MALSLEVPGLPQFLTLRYFDDEPFLPYKKNSSITDSQEPRIKDHLRAETWGRETDDLQEEEEQLKGMLAEITAQNGQNTDLHILQATFGCELQRNGSTRGFWKLGYDGQNFLTFDQKTLTWTVDGPSTQKNKTFWKTRAPRADLVKTFLDDICPAQLQRYLASLRNGLLNTGFPKVIVTFRNYPVGRITLTCRAFRLYTRVATLTWLQYRKPVQQKTFGSETILPSGDGTYQAWVSIRVLPGQESQFSCNLKHGNHNINEPAATEAPVYGARREQPPTSGVGSRVGKSLWSAMTTALVVISWTLSQKLMGPLLWFCSGGFCSFLQCW

Target ORF information:

RefSeq Version	XM_006540013.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus MHC I like leukocyte 1 (Mill1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006540013.2

ORF Insert Sequence:

ATGGCCTTGT CTCTGGAGGT GCCTGGGTTG CCCCAGTTCC TGACCCTGAG ATACTTCGAT 
GATGAGCCCT TCCTGCCCTA TAAGAAAAAC AGCAGCATAA CAGACTCCCA GGAACCCAGG 
ATCAAAGACC ATCTGAGAGC TGAGACCTGG GGAAGAGAGA CTGACGATCT TCAGGAAGAA 
GAGGAGCAAC TCAAAGGGAT GCTAGCTGAG ATCACAGCCC AGAACGGCCA GAATACGGAT 
CTTCACATCC TCCAGGCAAC CTTCGGCTGT GAGCTTCAAA GAAATGGAAG CACTAGAGGC 
TTCTGGAAAC TGGGCTATGA TGGGCAGAAC TTCCTCACCT TTGACCAGAA GACTCTCACA 
TGGACAGTGG ATGGACCTTC CACCCAGAAG AACAAGACAT TCTGGAAGAC ACGTGCACCC 
AGAGCTGATC TAGTTAAGAC ATTCTTGGAT GACATATGTC CTGCTCAGCT CCAGAGATAC 
CTTGCTTCCT TGAGAAATGG TCTGCTGAAT ACAGGTTTCC CAAAGGTGAT TGTGACCTTC 
AGGAACTATC CAGTGGGCAG GATCACACTG ACATGCCGGG CTTTTCGTCT GTATACCCGT 
GTGGCCACCC TGACCTGGCT TCAGTATAGA AAGCCAGTAC AGCAGAAAAC CTTTGGATCT 
GAAACTATCC TGCCCAGTGG GGATGGCACC TACCAGGCCT GGGTGTCCAT TCGGGTTCTT 
CCTGGACAGG AATCACAGTT CAGCTGCAAC TTGAAGCACG GCAACCACAA TATCAATGAA 
CCTGCTGCCA CTGAGGCCCC TGTCTATGGT GCGAGAAGAG AACAACCTCC CACCTCAGGT 
GTGGGAAGCA GGGTCGGGAA AAGCCTGTGG AGTGCAATGA CTACAGCTCT CGTGGTGATC 
TCCTGGACAT TAAGCCAGAA ACTGATGGGG CCTCTACTCT GGTTCTGCTC TGGTGGCTTC 
TGCTCTTTTC TACAGTGTTG GTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Mill1 ( XM_006540014.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006540077.1 Mus musculus MHC I like leukocyte 1 (Mill1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu38277
Clone ID Related Accession (Same CDS sequence)	XM_006540014.1 , XM_006540014.2
Accession Version	XM_006540014.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 459bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	MHC I like leukocyte 1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTGCTGT CCAGGAACCT CAGAGCCCTA GCTGCGATCC ACCTGTGGAT AGTGTACCTG 
CTCCTGGAGG ATTTACTGGG CACCTGCGCA GAGGGTGACA ACCAAAGACT GGTGGCTTCT 
GCTCCCTACC AAGATATTGA GATCACTCTG GAGAAGCCTA GAGTACAGGC GGTAGCAGAA 
CCCCACACTC TGCGCTATGA CCTCATGGCC TTGTCTCTGG AGGTGCCTGG GTTGCCCCAG 
TTCCTGACCC TGAGATACTT CGATGATGAG CCCTTCCTGC CCTATAAGAA AAACAGCAGC 
ATAACAGACT CCCAGGAACC CAGGATCAAA GACCATCTGA GAGCTGAGAC CTGGGGAAGA 
GAGACTGACG ATCTTCAGGA AGAAGAGGAG CAACTCAAAG GGATGCTAGC TGAGATCACA 
GCCCAGAACG GCCAGAATAC GGGCAACCTT CGGCTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006540077.1
CDS	379..837
Translation	MLLSRNLRALAAIHLWIVYLLLEDLLGTCAEGDNQRLVASAPYQDIEITLEKPRVQAVAEPHTLRYDLMALSLEVPGLPQFLTLRYFDDEPFLPYKKNSSITDSQEPRIKDHLRAETWGRETDDLQEEEEQLKGMLAEITAQNGQNTGNLRL

Target ORF information:

RefSeq Version	XM_006540014.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus MHC I like leukocyte 1 (Mill1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006540014.1

ORF Insert Sequence:

ATGCTGCTGT CCAGGAACCT CAGAGCCCTA GCTGCGATCC ACCTGTGGAT AGTGTACCTG 
CTCCTGGAGG ATTTACTGGG CACCTGCGCA GAGGGTGACA ACCAAAGACT GGTGGCTTCT 
GCTCCCTACC AAGATATTGA GATCACTCTG GAGAAGCCTA GAGTACAGGC GGTAGCAGAA 
CCCCACACTC TGCGCTATGA CCTCATGGCC TTGTCTCTGG AGGTGCCTGG GTTGCCCCAG 
TTCCTGACCC TGAGATACTT CGATGATGAG CCCTTCCTGC CCTATAAGAA AAACAGCAGC 
ATAACAGACT CCCAGGAACC CAGGATCAAA GACCATCTGA GAGCTGAGAC CTGGGGAAGA 
GAGACTGACG ATCTTCAGGA AGAAGAGGAG CAACTCAAAG GGATGCTAGC TGAGATCACA 
GCCCAGAACG GCCAGAATAC GGGCAACCTT CGGCTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Mill1 ( XM_006540014.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006540077.1 Mus musculus MHC I like leukocyte 1 (Mill1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu38277
Clone ID Related Accession (Same CDS sequence)	XM_006540014.1 , XM_006540014.2
Accession Version	XM_006540014.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 459bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	MHC I like leukocyte 1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006540014.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTGCTGT CCAGGAACCT CAGAGCCCTA GCTGCGATCC ACCTGTGGAT AGTGTACCTG 
CTCCTGGAGG ATTTACTGGG CACCTGCGCA GAGGGTGACA ACCAAAGACT GGTGGCTTCT 
GCTCCCTACC AAGATATTGA GATCACTCTG GAGAAGCCTA GAGTACAGGC GGTAGCAGAA 
CCCCACACTC TGCGCTATGA CCTCATGGCC TTGTCTCTGG AGGTGCCTGG GTTGCCCCAG 
TTCCTGACCC TGAGATACTT CGATGATGAG CCCTTCCTGC CCTATAAGAA AAACAGCAGC 
ATAACAGACT CCCAGGAACC CAGGATCAAA GACCATCTGA GAGCTGAGAC CTGGGGAAGA 
GAGACTGACG ATCTTCAGGA AGAAGAGGAG CAACTCAAAG GGATGCTAGC TGAGATCACA 
GCCCAGAACG GCCAGAATAC GGGCAACCTT CGGCTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006540077.1
CDS	386..844
Translation	MLLSRNLRALAAIHLWIVYLLLEDLLGTCAEGDNQRLVASAPYQDIEITLEKPRVQAVAEPHTLRYDLMALSLEVPGLPQFLTLRYFDDEPFLPYKKNSSITDSQEPRIKDHLRAETWGRETDDLQEEEEQLKGMLAEITAQNGQNTGNLRL

Target ORF information:

RefSeq Version	XM_006540014.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus MHC I like leukocyte 1 (Mill1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006540014.2

ORF Insert Sequence:

ATGCTGCTGT CCAGGAACCT CAGAGCCCTA GCTGCGATCC ACCTGTGGAT AGTGTACCTG 
CTCCTGGAGG ATTTACTGGG CACCTGCGCA GAGGGTGACA ACCAAAGACT GGTGGCTTCT 
GCTCCCTACC AAGATATTGA GATCACTCTG GAGAAGCCTA GAGTACAGGC GGTAGCAGAA 
CCCCACACTC TGCGCTATGA CCTCATGGCC TTGTCTCTGG AGGTGCCTGG GTTGCCCCAG 
TTCCTGACCC TGAGATACTT CGATGATGAG CCCTTCCTGC CCTATAAGAA AAACAGCAGC 
ATAACAGACT CCCAGGAACC CAGGATCAAA GACCATCTGA GAGCTGAGAC CTGGGGAAGA 
GAGACTGACG ATCTTCAGGA AGAAGAGGAG CAACTCAAAG GGATGCTAGC TGAGATCACA 
GCCCAGAACG GCCAGAATAC GGGCAACCTT CGGCTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Reversal of epigenetic silencing of MHC class I chain-related protein A and B improves immune recognition of Merkel cell carcinoma.
Scientific reports621678(2016 Feb)
Ritter C,Fan K,Paulson KG,Nghiem P,Schrama D,Becker JC

Recognition of the ligand-type specificity of classical and non-classical MHC I proteins.
FEBS letters585(21)3478-84(2011 Nov)
Mart?nez-Naves E,Lafuente EM,Reche PA

A role for the MHC class I-like Mill molecules in nutrient metabolism and wound healing.
Immunology and cell biology86(6)489-96(2008 Aug-Sep)
Rabinovich BA,Ketchem RR,Wolfson M,Goldstein L,Skelly M,Cosman D

MHC class I-like MILL molecules are beta2-microglobulin-associated, GPI-anchored glycoproteins that do not require TAP for cell surface expression.
Journal of immunology (Baltimore, Md. : 1950)177(5)3108-15(2006 Sep)
Kajikawa M,Baba T,Tomaru U,Watanabe Y,Koganei S,Tsuji-Kawahara S,Matsumoto N,Yamamoto K,Miyazawa M,Maenaka K,Ishizu A,Kasahara M

Reconstructing an ancestral mammalian immune supercomplex from a marsupial major histocompatibility complex.
PLoS biology4(3)e46(2006 Mar)
Belov K,Deakin JE,Papenfuss AT,Baker ML,Melman SD,Siddle HV,Gouin N,Goode DL,Sargeant TJ,Robinson MD,Wakefield MJ,Mahony S,Cross JG,Benos PV,Samollow PB,Speed TP,Graves JA,Miller RD

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Mill1 cDNA ORF clone, Mus musculus(house mouse)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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