Gene Symbol | Olfr225 |
Entrez Gene ID | 257886 |
Full Name | olfactory receptor 225 |
Synonyms | MOR256-51 |
General protein information |
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Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome | |
Summary | Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. There may be a polymorphism in the C-terminus of the encoded protein due to a single nucleotide insertion (rs228650303) found in some mouse strains. The GRCm38 reference genome encodes a protein with a poorly conserved C-terminus that is longer than other olfactory receptor proteins and may not function as an olfactory receptor. [provided by RefSeq, Jun 2015]. |