Parp12 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Parp12
Entrez Gene ID	243771
Full Name	poly (ADP-ribose) polymerase family, member 12
Synonyms	9930021O16,AA409132,AA536654,ARTD12,PARP-12,Zc3hdc1
General protein information	Preferred Names poly (ADP-ribose) polymerase family, member 12 Names poly [ADP-ribose] polymerase 12 ADP-ribosyltransferase diphtheria toxin-like 12 poly ADP-ribose polymerase 12 zinc finger CCCH domain-containing protein 1 zinc finger CCCH type domain containing 1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 6 Map Location: 6\|6 B1

mRNA and Protein(s)

mRNA	Protein	Name
NM_172893.3	NP_766481.2	protein mono-ADP-ribosyltransferase PARP12

Pathways from BioSystems

Homologies

Bos taurus (cattle)	PARP12	NP_001179273.1
Gallus gallus (chicken)	PARP12	XP_416333.4
Danio rerio (zebrafish)	parp12a	NP_001076321.1
Xenopus tropicalis (tropical clawed frog)	LOC100489821	XP_002942700.2
Rattus norvegicus (Norway rat)	Parp12	XP_003749764.1
Homo sapiens (human)	PARP12	NP_073587.1
Mus musculus (house mouse)	Parp12	NP_766481.2
	PARP12	XP_001108942.1
Canis lupus familiaris (dog)	PARP12	XP_539886.2
Pan troglodytes (chimpanzee)	PARP12	XP_519422.3

Gene Ontology
Bibliography

Related articles in PubMed

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)

PARP12, an interferon-stimulated gene involved in the control of protein translation and inflammation.
Welsby I, Hutin D, Gueydan C, Kruys V, Rongvaux A, Leo O
The Journal of biological chemistry289(38)26642-57(2014 Sep)

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H
Nucleic acids research42(Database issue)D802-9(2014 Jan)

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.
Guo G, Huss M, Tong GQ, Wang C, Li Sun L, Clarke ND, Robson P
Developmental cell18(4)675-85(2010 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

PARP12 is an interferon-induced gene with a potential role in cellular defenses against viral infections.
Title: PARP12, an interferon-stimulated gene involved in the control of protein translation and inflammation.

The following Parp12 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Parp12 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu04262	NM_172893.3 Latest version!	Mus musculus poly (ADP-ribose) polymerase family, member 12 (Parp12), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$391.30 $559.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Parp12 ( NM_172893.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_766481.2 Mus musculus poly (ADP-ribose) polymerase family, member 12 (Parp12), mRNA.

Price & Availability↑

CloneID	OMu04262
Clone ID Related Accession (Same CDS sequence)	NM_172893.3
Accession Version	NM_172893.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2136bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Mus musculus(house mouse)
Product	protein mono-ADP-ribosyltransferase PARP12
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK036886.1, BC120733.1 and BC048927.1. On Apr 1, 2008 this sequence version replaced NM_172893.2. ##Evidence-Data-START## Transcript exon combination :: AK053205.1, AK081528.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END##

ATGGCCCAGG CCGCGGTGGC AGTGGCAGAG GTGACCCAGC TGCTGTGCGC GGCGGGGGGC 
GCCTTGGAGT TGGCGGAGCT GCGGCGCCGC TTGCGAACCA GCCTGGGGAC CGACGCGCTG 
GAGCGGCTGC TGCGGGACTG CGGGCGCTTC GTGGTGGCCT CGCGGGCGGT CGTGGCCGTG 
GGCGCGGGCC GGGAGGCCGC GGCGGCAGCC TCGGAGCGCT TGGTGCTGGC CGTGTCGTCG 
CTGCGTCTGT GCCGCGCGCA TCAGGGCCCC AAGCCGGGCT GCACCGGGCT CTGCGCGCAG 
CTGCATCTCT GCAAGTTTCT CATCTACGGC AACTGCAAGT TCCTGAAGAC CGGGAAGAAC 
TGTAGGAATG GTCACAACTT GAAGACTGAT CACAACCTGA GTGTGTTGAG GACACATGGT 
GTTGACCACC TCACATATAC TGAGCTTTGC CAACTCTTGC TTCAGAATGA CCCTTCACTT 
TTGCCAGATA TATGCCTACA CTACAACAAA GGTGATGGAC CCTTCGGCTC TTGCTCCTTC 
CAAAAGCAGT GCATTAAACT CCATATCTGC CAGTACTTCC TACAGGGAGA GTGCAAGTTT 
GGCACAAGCT GTAAGAGGTC CCATGAGTTC ACTAACTCTG AGAGTCTGGA GCAGTTGGAA 
AGGTTGGGCT TAAGTTCTGA CCTGGTGAGC AGGCTACTCT CTACTTACCG GAATGCATAT 
GACATCAAGA ATAAGGGCTC AGCCCTCAGC AAAGTGTCTC CTTCTCCCGC AGGTCCACAG 
GGGAGTTCTG AAAGAAAAGA CAGTTCAGGT CCTGTGTCAC CAGGCACTCC TAGCCAGGAG 
GAGAGTGAAC AGATTTGCTT GTACCATATT CGGAAGAGTT GTAGCTTCCA AGAAAAGTGC 
CATCGAGTTC ATTTTCATTT ACCATATCGG TGGCAATTCT TGGATGGAGG CAAATGGAAG 
GATTTGGACA ACATGGAGCT TATTGAAGAA GCATATAGCA ATCCCAGTAA AGACAGGATT 
GTGTATACAG AGTCAGCTGC TGGCTTTCAC TTTGATAATT TAGACTTTAA TTCCATGAAG 
TTTGGTAATA CTCTGGCTCG CCGACTCTCC ACAGCTTCTT CAGTCACCAA ACCCCCACAT 
TTCATCCTTA CTACTGACTG GATTTGGTAC TGGATGGATG AGTTTGGTTC TTGGCAGGAA 
TATGGACGAC AAGGCTCAGG GCACCCTGTG ACCACCATCA GCAGCAGTGA CGTGGAAAGG 
GCTTACTTGG CATTCTGTGC TCCAGGGGCT GATGCCCAGG CAGCCACCTT GAAGTTCCAG 
GCTGGAAAAC ACAACTATGA GTTACACTTC AAAGCTTTTC TGCAGAAAAA CCTTGTGTAT 
GGCACTATCA GAAAGGTTTG TCGCAGACCC AAGTATGTGT CTCCCCAGGA TGTGCAGATG 
AAGCAGTCCT GCAATACTAA GTTACACGGC CCAAAGAGCA TCCCAGACTA CTGGGACCCT 
GCAGCCCTGC CTGACCTGGG ATTTAAGAAG ATCACTCTGA GTTCTTCCTC AGAAGAGTAT 
CAGAAGGTGT GGAACATCTT CAACCGTACA CTACCTTTCT ACTTTGTTCA GAAGATCGAG 
CGGATCCAGA ACATGGGCCT GTGGGAAGTC TACCAGTGGC AAAAATGTCA GATGCAGAAG 
CAAAATGGGG GGAAGGAAGT AGACGAGAGG CAGCTGTTTC ATGGTACTAG TGCCAACTTC 
GTGGATGCCA TCTGCCAGCA GAACTTTGAC TGGCGGGTCT GTGGTCTGCA CGGCACATCC 
TATGGCAAAG GGAGCTACTT TGCGAGAGAT GCCGCCTATT CGCACCACTA CAGTAAATCC 
GACACACACT CTCACATGAT GTTCCTGGCC CGGGTGCTGG TCGGAGATTT CGTCAGGGGC 
AGCACTTCCT TCGTCCGCCC TCCAGCCAAG GAAGGCCAGA GCAATGCCTT CTATGACAGC 
TGCGTGAACA GCATGTCCGA CCCAACCATC TTTGTAGTTT TTGAGAAGCA CCAGGTCTAC 
CCCGAGTACC TCATTCAATA CTCTACCTCC TCCAAGCCCC CAGCTAGCCC CTCCATCTTT 
GTTGCCCTAG GTAACTTGTT CACTAGCCGC CAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_766481.2
CDS	191..2326
Translation	MAQAAVAVAEVTQLLCAAGGALELAELRRRLRTSLGTDALERLLRDCGRFVVASRAVVAVGAGREAAAAASERLVLAVSSLRLCRAHQGPKPGCTGLCAQLHLCKFLIYGNCKFLKTGKNCRNGHNLKTDHNLSVLRTHGVDHLTYTELCQLLLQNDPSLLPDICLHYNKGDGPFGSCSFQKQCIKLHICQYFLQGECKFGTSCKRSHEFTNSESLEQLERLGLSSDLVSRLLSTYRNAYDIKNKGSALSKVSPSPAGPQGSSERKDSSGPVSPGTPSQEESEQICLYHIRKSCSFQEKCHRVHFHLPYRWQFLDGGKWKDLDNMELIEEAYSNPSKDRIVYTESAAGFHFDNLDFNSMKFGNTLARRLSTASSVTKPPHFILTTDWIWYWMDEFGSWQEYGRQGSGHPVTTISSSDVERAYLAFCAPGADAQAATLKFQAGKHNYELHFKAFLQKNLVYGTIRKVCRRPKYVSPQDVQMKQSCNTKLHGPKSIPDYWDPAALPDLGFKKITLSSSSEEYQKVWNIFNRTLPFYFVQKIERIQNMGLWEVYQWQKCQMQKQNGGKEVDERQLFHGTSANFVDAICQQNFDWRVCGLHGTSYGKGSYFARDAAYSHHYSKSDTHSHMMFLARVLVGDFVRGSTSFVRPPAKEGQSNAFYDSCVNSMSDPTIFVVFEKHQVYPEYLIQYSTSSKPPASPSIFVALGNLFTSRQ

Target ORF information:

RefSeq Version	NM_172893.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus poly (ADP-ribose) polymerase family, member 12 (Parp12), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_172893.3

ORF Insert Sequence:

ATGGCCCAGG CCGCGGTGGC AGTGGCAGAG GTGACCCAGC TGCTGTGCGC GGCGGGGGGC 
GCCTTGGAGT TGGCGGAGCT GCGGCGCCGC TTGCGAACCA GCCTGGGGAC CGACGCGCTG 
GAGCGGCTGC TGCGGGACTG CGGGCGCTTC GTGGTGGCCT CGCGGGCGGT CGTGGCCGTG 
GGCGCGGGCC GGGAGGCCGC GGCGGCAGCC TCGGAGCGCT TGGTGCTGGC CGTGTCGTCG 
CTGCGTCTGT GCCGCGCGCA TCAGGGCCCC AAGCCGGGCT GCACCGGGCT CTGCGCGCAG 
CTGCATCTCT GCAAGTTTCT CATCTACGGC AACTGCAAGT TCCTGAAGAC CGGGAAGAAC 
TGTAGGAATG GTCACAACTT GAAGACTGAT CACAACCTGA GTGTGTTGAG GACACATGGT 
GTTGACCACC TCACATATAC TGAGCTTTGC CAACTCTTGC TTCAGAATGA CCCTTCACTT 
TTGCCAGATA TATGCCTACA CTACAACAAA GGTGATGGAC CCTTCGGCTC TTGCTCCTTC 
CAAAAGCAGT GCATTAAACT CCATATCTGC CAGTACTTCC TACAGGGAGA GTGCAAGTTT 
GGCACAAGCT GTAAGAGGTC CCATGAGTTC ACTAACTCTG AGAGTCTGGA GCAGTTGGAA 
AGGTTGGGCT TAAGTTCTGA CCTGGTGAGC AGGCTACTCT CTACTTACCG GAATGCATAT 
GACATCAAGA ATAAGGGCTC AGCCCTCAGC AAAGTGTCTC CTTCTCCCGC AGGTCCACAG 
GGGAGTTCTG AAAGAAAAGA CAGTTCAGGT CCTGTGTCAC CAGGCACTCC TAGCCAGGAG 
GAGAGTGAAC AGATTTGCTT GTACCATATT CGGAAGAGTT GTAGCTTCCA AGAAAAGTGC 
CATCGAGTTC ATTTTCATTT ACCATATCGG TGGCAATTCT TGGATGGAGG CAAATGGAAG 
GATTTGGACA ACATGGAGCT TATTGAAGAA GCATATAGCA ATCCCAGTAA AGACAGGATT 
GTGTATACAG AGTCAGCTGC TGGCTTTCAC TTTGATAATT TAGACTTTAA TTCCATGAAG 
TTTGGTAATA CTCTGGCTCG CCGACTCTCC ACAGCTTCTT CAGTCACCAA ACCCCCACAT 
TTCATCCTTA CTACTGACTG GATTTGGTAC TGGATGGATG AGTTTGGTTC TTGGCAGGAA 
TATGGACGAC AAGGCTCAGG GCACCCTGTG ACCACCATCA GCAGCAGTGA CGTGGAAAGG 
GCTTACTTGG CATTCTGTGC TCCAGGGGCT GATGCCCAGG CAGCCACCTT GAAGTTCCAG 
GCTGGAAAAC ACAACTATGA GTTACACTTC AAAGCTTTTC TGCAGAAAAA CCTTGTGTAT 
GGCACTATCA GAAAGGTTTG TCGCAGACCC AAGTATGTGT CTCCCCAGGA TGTGCAGATG 
AAGCAGTCCT GCAATACTAA GTTACACGGC CCAAAGAGCA TCCCAGACTA CTGGGACCCT 
GCAGCCCTGC CTGACCTGGG ATTTAAGAAG ATCACTCTGA GTTCTTCCTC AGAAGAGTAT 
CAGAAGGTGT GGAACATCTT CAACCGTACA CTACCTTTCT ACTTTGTTCA GAAGATCGAG 
CGGATCCAGA ACATGGGCCT GTGGGAAGTC TACCAGTGGC AAAAATGTCA GATGCAGAAG 
CAAAATGGGG GGAAGGAAGT AGACGAGAGG CAGCTGTTTC ATGGTACTAG TGCCAACTTC 
GTGGATGCCA TCTGCCAGCA GAACTTTGAC TGGCGGGTCT GTGGTCTGCA CGGCACATCC 
TATGGCAAAG GGAGCTACTT TGCGAGAGAT GCCGCCTATT CGCACCACTA CAGTAAATCC 
GACACACACT CTCACATGAT GTTCCTGGCC CGGGTGCTGG TCGGAGATTT CGTCAGGGGC 
AGCACTTCCT TCGTCCGCCC TCCAGCCAAG GAAGGCCAGA GCAATGCCTT CTATGACAGC 
TGCGTGAACA GCATGTCCGA CCCAACCATC TTTGTAGTTT TTGAGAAGCA CCAGGTCTAC 
CCCGAGTACC TCATTCAATA CTCTACCTCC TCCAAGCCCC CAGCTAGCCC CTCCATCTTT 
GTTGCCCTAG GTAACTTGTT CACTAGCCGC CAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie SM,Fuchs H,Gailus-Durner V,Galli A,Gambadoro A,Gallegos J,Guo S,Horner NR,Hsu CW,Johnson SJ,Kalaga S,Keith LC,Lanoue L,Lawson TN,Lek M,Mark M,Marschall S,Mason J,McElwee ML,Newbigging S,Nutter LM,Peterson KA,Ramirez-Solis R,Rowland DJ,Ryder E,Samocha KE,Seavitt JR,Selloum M,Szoke-Kovacs Z,Tamura M,Trainor AG,Tudose I,Wakana S,Warren J,Wendling O,West DB,Wong L,Yoshiki A,,,,,,,,,MacArthur DG,Tocchini-Valentini GP,Gao X,Flicek P,Bradley A,Skarnes WC,Justice MJ,Parkinson HE,Moore M,Wells S,Braun RE,Svenson KL,de Angelis MH,Herault Y,Mohun T,Mallon AM,Henkelman RM,Brown SD,Adams DJ,Lloyd KC,McKerlie C,Beaudet AL,Bu?an M,Murray SA

PARP12, an interferon-stimulated gene involved in the control of protein translation and inflammation.
The Journal of biological chemistry289(38)26642-57(2014 Sep)
Welsby I,Hutin D,Gueydan C,Kruys V,Rongvaux A,Leo O

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Nucleic acids research42(Database issue)D802-9(2014 Jan)
Koscielny G,Yaikhom G,Iyer V,Meehan TF,Morgan H,Atienza-Herrero J,Blake A,Chen CK,Easty R,Di Fenza A,Fiegel T,Grifiths M,Horne A,Karp NA,Kurbatova N,Mason JC,Matthews P,Oakley DJ,Qazi A,Regnart J,Retha A,Santos LA,Sneddon DJ,Warren J,Westerberg H,Wilson RJ,Melvin DG,Smedley D,Brown SD,Flicek P,Skarnes WC,Mallon AM,Parkinson H

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.
Developmental cell18(4)675-85(2010 Apr)
Guo G,Huss M,Tong GQ,Wang C,Li Sun L,Clarke ND,Robson P

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Parp12 cDNA ORF clone, Mus musculus(house mouse)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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