Best1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Best1
Entrez Gene ID	24115
Full Name	bestrophin 1
Synonyms	Bmd,Vmd2,mBest1
General protein information	Preferred Names bestrophin 1 Names bestrophin-1 best macular dystrophy vitelliform macular dystrophy 2 homolog vitelliform macular dystrophy protein 2 homolog
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 19 Map Location: 19\|19 A

mRNA and Protein(s)

mRNA	Protein	Name
XM_011247250.1	XP_011245552.1	bestrophin-1 isoform X1
NM_011913.2	NP_036043.2	bestrophin-1

Pathways from BioSystems

Homologies

Homo sapiens (human)	BEST1	NP_004174.1
Bos taurus (cattle)	BEST1	NP_001073714.1
Mus musculus (house mouse)	Best1	NP_036043.2
Danio rerio (zebrafish)	LOC560608	XP_689098.3
Pan troglodytes (chimpanzee)	BEST1	XP_001151529.1
	LOC718993	XP_001116591.1
Xenopus tropicalis (tropical clawed frog)	best1	NP_001155223.1
Canis lupus familiaris (dog)	BEST1	NP_001091014.1
Rattus norvegicus (Norway rat)	Best1	NP_001011940.1
Gallus gallus (chicken)	BEST1	XP_004941545.1

Gene Ontology
Bibliography

Related articles in PubMed

Direct interaction with 14-3-3? promotes surface expression of Best1 channel in astrocyte.
Oh SJ, Woo J, Lee YS, Cho M, Kim E, Cho NC, Park JY, Pae AN, Justin Lee C, Hwang EM
Molecular brain10(1)51(2017 Nov)

Contribution of Ion Channels in Calcium Signaling Regulating Phagocytosis: MaxiK, Cav1.3 and Bestrophin-1.
Strau? O, Reichhart N, Gomez NM, M?ller C
Advances in experimental medicine and biology854739-44(2016)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data suggest that the ion channels CaV1.3, bestrophin-1 and maxiK were identified as players in the regulation of photoreceptor outer segments (POS) phagocytosis by the retinal pigment epithelium (RPE).
Title: Contribution of Ion Channels in Calcium Signaling Regulating Phagocytosis: MaxiK, Cav1.3 and Bestrophin-1.

Best1-mediated astrocytic glutamate activates the synaptic N-methyl-D-aspartate receptor (NMDAR) and modulates NMDAR-dependent synaptic plasticity.
Title: Channel-mediated astrocytic glutamate modulates hippocampal synaptic plasticity by activating postsynaptic NMDA receptors.

Bestrophin-1 functions as an intracellular Cl channel which helps to accumulate and to release Ca(2+) from stores by conducting the counterion for Ca(2+).
Title: The role of bestrophin-1 in intracellular Ca(2+) signaling.

Best1, located at the microdomains near the synaptic junctions, has a significantly high permeability to glutamate in vivo.
Title: High glutamate permeability and distal localization of Best1 channel in CA1 hippocampal astrocyte.

Results show that different mutations in Best1 cause differential effects on its localization and that this effect varies with the presence or absence of wild-type (WT) Best1.
Title: Differential effects of Best disease causing missense mutations on bestrophin-1 trafficking.

The following Best1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Best1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu21134	NM_011913.2 Latest version!	Mus musculus bestrophin 1 (Best1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OMu21134	XM_011247250.1 Latest version!	Mus musculus bestrophin 1 (Best1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Best1 ( NM_011913.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_036043.2 Mus musculus bestrophin 1 (Best1), mRNA.

Price & Availability↑

CloneID	OMu21134
Clone ID Related Accession (Same CDS sequence)	XM_011247250.1 , NM_011913.2
Accession Version	NM_011913.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1656bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Mus musculus(house mouse)
Product	bestrophin-1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY105692.1, BY714344.1, AY450427.1, AK006549.1 and BX634624.1. On Nov 15, 2007 this sequence version replaced NM_011913.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: AY450427.1, BC139060.1 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMN00849384 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGACTATCA CCTACACAAA CAAAGTAGCC AATGCCCGCC TCGGTTCGTT CTCGTCCCTC 
CTCCTGTGCT GGCGAGGCAG CATCTACAAG CTGCTGTATG GAGAATTCCT TGTCTTCATA 
TTCCTCTACT ATTCCATCCG TGGACTCTAC AGAATGGTTC TCTCGAGTGA TCAGCAGCTG 
TTGTTTGAGA AGCTGGCTCT GTACTGCGAC AGCTACATTC AGCTCATCCC TATATCCTTC 
GTTCTGGGTT TCTATGTTAC ATTGGTGGTG AGCCGCTGGT GGAGCCAGTA CGAGAACTTG 
CCGTGGCCCG ACCGCCTCAT GATCCAGGTG TCTAGCTTCG TGGAGGGCAA GGATGAGGAA 
GGCCGTTTGC TGCGGCGCAC GCTCATCCGC TACGCCATCC TGGGCCAAGT GCTCATCCTG 
CGCAGCATCA GCACCTCGGT CTACAAGCGC TTTCCCACTC TTCACCACCT GGTGCTAGCA 
GGTTTTATGA CCCATGGGGA ACATAAGCAG TTGCAGAAGT TGGGCCTACC ACACAACACA 
TTCTGGGTGC CCTGGGTGTG GTTTGCCAAC TTGTCAATGA AGGCCTATCT TGGAGGTCGA 
ATCCGGGACA CCGTCCTGCT CCAGAGCCTG ATGAATGAGG TGTGTACTTT GCGTACTCAG 
TGTGGACAGC TGTATGCCTA CGACTGGATA AGTATCCCAT TGGTGTACAC ACAGGTGGTG 
ACAGTGGCAG TATACAGCTT TTTCCTTGCA TGCTTGATCG GGAGGCAGTT TCTGAACCCA 
AACAAGGACT ACCCAGGCCA TGAGATGGAT CTGGTTGTGC CTGTCTTCAC AATCCTGCAA 
TTCTTATTCT ACATGGGCTG GCTGAAGGTG GCAGAACAGC TCATCAACCC CTTCGGGGAG 
GACGATGATG ATTTTGAGAC TAACTGGATC ATTGACAGAA ACCTGCAGGT GTCCCTGTTG 
TCCGTGGATG GGATGCACCA GAACTTGCCT CCCATGGAAC GTGACATGTA CTGGAACGAG 
GCAGCGCCTC AGCCGCCCTA CACAGCTGCT TCTGCCAGGT CTCGCCGGCA TTCCTTCATG 
GGCTCCACCT TCAACATCAG CCTAAAGAAA GAAGACTTAG AGCTTTGGTC AAAAGAGGAG 
GCTGACACGG ATAAGAAAGA GAGTGGCTAT AGCAGCACCA TAGGCTGCTT CTTAGGACTG 
CAACCCAAAA ACTACCATCT TCCCTTGAAA GACTTAAAGA CCAAACTATT GTGTTCTAAG 
AACCCCCTCC TCGAAGGCCA GTGTAAGGAT GCCAACCAGA AAAACCAGAA AGATGTCTGG 
AAATTTAAGG GTCTGGACTT CTTGAAATGT GTTCCAAGGT TTAAGAGGAG AGGCTCCCAT 
TGTGGCCCAC AGGCACCCAG CAGCCACCCT ACTGAGCAGT CAGCACCCTC CAGTTCAGAC 
ACAGGTGATG GGCCTTCCAC AGATTACCAA GAAATCTGTC ACATGAAAAA GAAAACTGTG 
GAGTTTAACT TGAACATTCC AGAGAGCCCC ACAGAACATC TTCAACAGCG CCGTTTGGAC 
CAGATGTCAA CCAATATACA GGCTCTAATG AAGGAGCATG CAGAGTCCTA TCCCTACAGG 
GATGAAGCTG GCACCAAACC TGTTCTCTAT GAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_036043.2
CDS	213..1868
Translation	MTITYTNKVANARLGSFSSLLLCWRGSIYKLLYGEFLVFIFLYYSIRGLYRMVLSSDQQLLFEKLALYCDSYIQLIPISFVLGFYVTLVVSRWWSQYENLPWPDRLMIQVSSFVEGKDEEGRLLRRTLIRYAILGQVLILRSISTSVYKRFPTLHHLVLAGFMTHGEHKQLQKLGLPHNTFWVPWVWFANLSMKAYLGGRIRDTVLLQSLMNEVCTLRTQCGQLYAYDWISIPLVYTQVVTVAVYSFFLACLIGRQFLNPNKDYPGHEMDLVVPVFTILQFLFYMGWLKVAEQLINPFGEDDDDFETNWIIDRNLQVSLLSVDGMHQNLPPMERDMYWNEAAPQPPYTAASARSRRHSFMGSTFNISLKKEDLELWSKEEADTDKKESGYSSTIGCFLGLQPKNYHLPLKDLKTKLLCSKNPLLEGQCKDANQKNQKDVWKFKGLDFLKCVPRFKRRGSHCGPQAPSSHPTEQSAPSSSDTGDGPSTDYQEICHMKKKTVEFNLNIPESPTEHLQQRRLDQMSTNIQALMKEHAESYPYRDEAGTKPVLYE

Target ORF information:

RefSeq Version	NM_011913.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus bestrophin 1 (Best1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_011913.2

ORF Insert Sequence:

ATGACTATCA CCTACACAAA CAAAGTAGCC AATGCCCGCC TCGGTTCGTT CTCGTCCCTC 
CTCCTGTGCT GGCGAGGCAG CATCTACAAG CTGCTGTATG GAGAATTCCT TGTCTTCATA 
TTCCTCTACT ATTCCATCCG TGGACTCTAC AGAATGGTTC TCTCGAGTGA TCAGCAGCTG 
TTGTTTGAGA AGCTGGCTCT GTACTGCGAC AGCTACATTC AGCTCATCCC TATATCCTTC 
GTTCTGGGTT TCTATGTTAC ATTGGTGGTG AGCCGCTGGT GGAGCCAGTA CGAGAACTTG 
CCGTGGCCCG ACCGCCTCAT GATCCAGGTG TCTAGCTTCG TGGAGGGCAA GGATGAGGAA 
GGCCGTTTGC TGCGGCGCAC GCTCATCCGC TACGCCATCC TGGGCCAAGT GCTCATCCTG 
CGCAGCATCA GCACCTCGGT CTACAAGCGC TTTCCCACTC TTCACCACCT GGTGCTAGCA 
GGTTTTATGA CCCATGGGGA ACATAAGCAG TTGCAGAAGT TGGGCCTACC ACACAACACA 
TTCTGGGTGC CCTGGGTGTG GTTTGCCAAC TTGTCAATGA AGGCCTATCT TGGAGGTCGA 
ATCCGGGACA CCGTCCTGCT CCAGAGCCTG ATGAATGAGG TGTGTACTTT GCGTACTCAG 
TGTGGACAGC TGTATGCCTA CGACTGGATA AGTATCCCAT TGGTGTACAC ACAGGTGGTG 
ACAGTGGCAG TATACAGCTT TTTCCTTGCA TGCTTGATCG GGAGGCAGTT TCTGAACCCA 
AACAAGGACT ACCCAGGCCA TGAGATGGAT CTGGTTGTGC CTGTCTTCAC AATCCTGCAA 
TTCTTATTCT ACATGGGCTG GCTGAAGGTG GCAGAACAGC TCATCAACCC CTTCGGGGAG 
GACGATGATG ATTTTGAGAC TAACTGGATC ATTGACAGAA ACCTGCAGGT GTCCCTGTTG 
TCCGTGGATG GGATGCACCA GAACTTGCCT CCCATGGAAC GTGACATGTA CTGGAACGAG 
GCAGCGCCTC AGCCGCCCTA CACAGCTGCT TCTGCCAGGT CTCGCCGGCA TTCCTTCATG 
GGCTCCACCT TCAACATCAG CCTAAAGAAA GAAGACTTAG AGCTTTGGTC AAAAGAGGAG 
GCTGACACGG ATAAGAAAGA GAGTGGCTAT AGCAGCACCA TAGGCTGCTT CTTAGGACTG 
CAACCCAAAA ACTACCATCT TCCCTTGAAA GACTTAAAGA CCAAACTATT GTGTTCTAAG 
AACCCCCTCC TCGAAGGCCA GTGTAAGGAT GCCAACCAGA AAAACCAGAA AGATGTCTGG 
AAATTTAAGG GTCTGGACTT CTTGAAATGT GTTCCAAGGT TTAAGAGGAG AGGCTCCCAT 
TGTGGCCCAC AGGCACCCAG CAGCCACCCT ACTGAGCAGT CAGCACCCTC CAGTTCAGAC 
ACAGGTGATG GGCCTTCCAC AGATTACCAA GAAATCTGTC ACATGAAAAA GAAAACTGTG 
GAGTTTAACT TGAACATTCC AGAGAGCCCC ACAGAACATC TTCAACAGCG CCGTTTGGAC 
CAGATGTCAA CCAATATACA GGCTCTAATG AAGGAGCATG CAGAGTCCTA TCCCTACAGG 
GATGAAGCTG GCACCAAACC TGTTCTCTAT GAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Best1 ( XM_011247250.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011245552.1 Mus musculus bestrophin 1 (Best1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu21134
Clone ID Related Accession (Same CDS sequence)	XM_011247250.1 , NM_011913.2
Accession Version	XM_011247250.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1656bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-02-08
Organism	Mus musculus(House mouse)
Product	bestrophin-1 isoform X1
Comment

ATGACTATCA CCTACACAAA CAAAGTAGCC AATGCCCGCC TCGGTTCGTT CTCGTCCCTC 
CTCCTGTGCT GGCGAGGCAG CATCTACAAG CTGCTGTATG GAGAATTCCT TGTCTTCATA 
TTCCTCTACT ATTCCATCCG TGGACTCTAC AGAATGGTTC TCTCGAGTGA TCAGCAGCTG 
TTGTTTGAGA AGCTGGCTCT GTACTGCGAC AGCTACATTC AGCTCATCCC TATATCCTTC 
GTTCTGGGTT TCTATGTTAC ATTGGTGGTG AGCCGCTGGT GGAGCCAGTA CGAGAACTTG 
CCGTGGCCCG ACCGCCTCAT GATCCAGGTG TCTAGCTTCG TGGAGGGCAA GGATGAGGAA 
GGCCGTTTGC TGCGGCGCAC GCTCATCCGC TACGCCATCC TGGGCCAAGT GCTCATCCTG 
CGCAGCATCA GCACCTCGGT CTACAAGCGC TTTCCCACTC TTCACCACCT GGTGCTAGCA 
GGTTTTATGA CCCATGGGGA ACATAAGCAG TTGCAGAAGT TGGGCCTACC ACACAACACA 
TTCTGGGTGC CCTGGGTGTG GTTTGCCAAC TTGTCAATGA AGGCCTATCT TGGAGGTCGA 
ATCCGGGACA CCGTCCTGCT CCAGAGCCTG ATGAATGAGG TGTGTACTTT GCGTACTCAG 
TGTGGACAGC TGTATGCCTA CGACTGGATA AGTATCCCAT TGGTGTACAC ACAGGTGGTG 
ACAGTGGCAG TATACAGCTT TTTCCTTGCA TGCTTGATCG GGAGGCAGTT TCTGAACCCA 
AACAAGGACT ACCCAGGCCA TGAGATGGAT CTGGTTGTGC CTGTCTTCAC AATCCTGCAA 
TTCTTATTCT ACATGGGCTG GCTGAAGGTG GCAGAACAGC TCATCAACCC CTTCGGGGAG 
GACGATGATG ATTTTGAGAC TAACTGGATC ATTGACAGAA ACCTGCAGGT GTCCCTGTTG 
TCCGTGGATG GGATGCACCA GAACTTGCCT CCCATGGAAC GTGACATGTA CTGGAACGAG 
GCAGCGCCTC AGCCGCCCTA CACAGCTGCT TCTGCCAGGT CTCGCCGGCA TTCCTTCATG 
GGCTCCACCT TCAACATCAG CCTAAAGAAA GAAGACTTAG AGCTTTGGTC AAAAGAGGAG 
GCTGACACGG ATAAGAAAGA GAGTGGCTAT AGCAGCACCA TAGGCTGCTT CTTAGGACTG 
CAACCCAAAA ACTACCATCT TCCCTTGAAA GACTTAAAGA CCAAACTATT GTGTTCTAAG 
AACCCCCTCC TCGAAGGCCA GTGTAAGGAT GCCAACCAGA AAAACCAGAA AGATGTCTGG 
AAATTTAAGG GTCTGGACTT CTTGAAATGT GTTCCAAGGT TTAAGAGGAG AGGCTCCCAT 
TGTGGCCCAC AGGCACCCAG CAGCCACCCT ACTGAGCAGT CAGCACCCTC CAGTTCAGAC 
ACAGGTGATG GGCCTTCCAC AGATTACCAA GAAATCTGTC ACATGAAAAA GAAAACTGTG 
GAGTTTAACT TGAACATTCC AGAGAGCCCC ACAGAACATC TTCAACAGCG CCGTTTGGAC 
CAGATGTCAA CCAATATACA GGCTCTAATG AAGGAGCATG CAGAGTCCTA TCCCTACAGG 
GATGAAGCTG GCACCAAACC TGTTCTCTAT GAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq

XP_011245552.1

Translation

MTITYTNKVANARLGSFSSLLLCWRGSIYKLLYGEFLVFIFLYYSIRGLYRMVLSSDQQLLFEKLALYCDSYIQLIPISFVLGFYVTLVVSRWWSQYENLPWPDRLMIQVSSFVEGKDEEGRLLRRTLIRYAILGQVLILRSISTSVYKRFPTLHHLVLAGFMTHGEHKQLQKLGLPHNTFWVPWVWFANLSMKAYLGGRIRDTVLLQSLMNEVCTLRTQCGQLYAYDWISIPLVYTQVVTVAVYSFFLACLIGRQFLNPNKDYPGHEMDLVVPVFTILQFLFYMGWLKVAEQLINPFGEDDDDFETNWIIDRNLQVSLLSVDGMHQNLPPMERDMYWNEAAPQPPYTAASARSRRHSFMGSTFNISLKKEDLELWSKEEADTDKKESGYSSTIGCFLGLQPKNYHLPLKDLKTKLLCSKNPLLEGQCKDANQKNQKDVWKFKGLDFLKCVPRFKRRGSHCGPQAPSSHPTEQSAPSSSDTGDGPSTDYQEICHMKKKTVEFNLNIPESPTEHLQQRRLDQMSTNIQALMKEHAESYPYRDEAGTKPVLYE

Target ORF information:

RefSeq Version	XM_011247250.1
Organism	Mus musculus(House mouse)
Definition	Mus musculus bestrophin 1 (Best1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011247250.1

ORF Insert Sequence:

ATGACTATCA CCTACACAAA CAAAGTAGCC AATGCCCGCC TCGGTTCGTT CTCGTCCCTC 
CTCCTGTGCT GGCGAGGCAG CATCTACAAG CTGCTGTATG GAGAATTCCT TGTCTTCATA 
TTCCTCTACT ATTCCATCCG TGGACTCTAC AGAATGGTTC TCTCGAGTGA TCAGCAGCTG 
TTGTTTGAGA AGCTGGCTCT GTACTGCGAC AGCTACATTC AGCTCATCCC TATATCCTTC 
GTTCTGGGTT TCTATGTTAC ATTGGTGGTG AGCCGCTGGT GGAGCCAGTA CGAGAACTTG 
CCGTGGCCCG ACCGCCTCAT GATCCAGGTG TCTAGCTTCG TGGAGGGCAA GGATGAGGAA 
GGCCGTTTGC TGCGGCGCAC GCTCATCCGC TACGCCATCC TGGGCCAAGT GCTCATCCTG 
CGCAGCATCA GCACCTCGGT CTACAAGCGC TTTCCCACTC TTCACCACCT GGTGCTAGCA 
GGTTTTATGA CCCATGGGGA ACATAAGCAG TTGCAGAAGT TGGGCCTACC ACACAACACA 
TTCTGGGTGC CCTGGGTGTG GTTTGCCAAC TTGTCAATGA AGGCCTATCT TGGAGGTCGA 
ATCCGGGACA CCGTCCTGCT CCAGAGCCTG ATGAATGAGG TGTGTACTTT GCGTACTCAG 
TGTGGACAGC TGTATGCCTA CGACTGGATA AGTATCCCAT TGGTGTACAC ACAGGTGGTG 
ACAGTGGCAG TATACAGCTT TTTCCTTGCA TGCTTGATCG GGAGGCAGTT TCTGAACCCA 
AACAAGGACT ACCCAGGCCA TGAGATGGAT CTGGTTGTGC CTGTCTTCAC AATCCTGCAA 
TTCTTATTCT ACATGGGCTG GCTGAAGGTG GCAGAACAGC TCATCAACCC CTTCGGGGAG 
GACGATGATG ATTTTGAGAC TAACTGGATC ATTGACAGAA ACCTGCAGGT GTCCCTGTTG 
TCCGTGGATG GGATGCACCA GAACTTGCCT CCCATGGAAC GTGACATGTA CTGGAACGAG 
GCAGCGCCTC AGCCGCCCTA CACAGCTGCT TCTGCCAGGT CTCGCCGGCA TTCCTTCATG 
GGCTCCACCT TCAACATCAG CCTAAAGAAA GAAGACTTAG AGCTTTGGTC AAAAGAGGAG 
GCTGACACGG ATAAGAAAGA GAGTGGCTAT AGCAGCACCA TAGGCTGCTT CTTAGGACTG 
CAACCCAAAA ACTACCATCT TCCCTTGAAA GACTTAAAGA CCAAACTATT GTGTTCTAAG 
AACCCCCTCC TCGAAGGCCA GTGTAAGGAT GCCAACCAGA AAAACCAGAA AGATGTCTGG 
AAATTTAAGG GTCTGGACTT CTTGAAATGT GTTCCAAGGT TTAAGAGGAG AGGCTCCCAT 
TGTGGCCCAC AGGCACCCAG CAGCCACCCT ACTGAGCAGT CAGCACCCTC CAGTTCAGAC 
ACAGGTGATG GGCCTTCCAC AGATTACCAA GAAATCTGTC ACATGAAAAA GAAAACTGTG 
GAGTTTAACT TGAACATTCC AGAGAGCCCC ACAGAACATC TTCAACAGCG CCGTTTGGAC 
CAGATGTCAA CCAATATACA GGCTCTAATG AAGGAGCATG CAGAGTCCTA TCCCTACAGG 
GATGAAGCTG GCACCAAACC TGTTCTCTAT GAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Direct interaction with 14-3-3? promotes surface expression of Best1 channel in astrocyte.
Molecular brain10(1)51(2017 Nov)
Oh SJ,Woo J,Lee YS,Cho M,Kim E,Cho NC,Park JY,Pae AN,Justin Lee C,Hwang EM

Contribution of Ion Channels in Calcium Signaling Regulating Phagocytosis: MaxiK, Cav1.3 and Bestrophin-1.
Advances in experimental medicine and biology854739-44(2016)
Strau? O,Reichhart N,Gomez NM,M?ller C

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Best1 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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