Galp cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Galp
Entrez Gene ID	232836
Full Name	galanin-like peptide
General protein information	Preferred Names galanin-like peptide Names galanin-like peptide
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 7 Map Location: 7\|7 A1

mRNA and Protein(s)

mRNA	Protein	Name
XM_006539789.1	XP_006539852.1	galanin-like peptide isoform X1
NM_178028.2	NP_821171.1	galanin-like peptide preproprotein

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Galp	NP_072155.1
Homo sapiens (human)	GALP	NP_149097.1
Mus musculus (house mouse)	Galp	NP_821171.1
Canis lupus familiaris (dog)	GALP	XP_005616158.1
Pan troglodytes (chimpanzee)	GALP	XP_524495.2
	GALP	XP_001090902.1

Gene Ontology
Bibliography

Related articles in PubMed

Anti-obesity effect of intranasal administration of galanin-like peptide (GALP) in obese mice.
Kageyama H, Shiba K, Hirako S, Wada N, Yamanaka S, Nogi Y, Takenoya F, Nonaka N, Hirano T, Inoue S, Shioda S
Scientific reports628200(2016 Jun)

Galanin-like peptide (GALP) neurone-specific phosphoinositide 3-kinase signalling regulates GALP mRNA levels in the hypothalamus of males and luteinising hormone levels in both sexes.
Aziz R, Beymer M, Negr?n AL, Newshan A, Yu G, Rosati B, McKinnon D, Fukuda M, Lin RZ, Mayer C, Boehm U, Acosta-Mart?nez M
Journal of neuroendocrinology26(7)426-38(2014 Jul)

Interactive effect of galanin-like peptide (GALP) and spontaneous exercise on energy metabolism.
Ito K, Kageyama H, Hirako S, Wang L, Takenoya F, Ogawa T, Shioda S
Peptides49109-16(2013 Nov)

Distribution of alarin immunoreactivity in the mouse brain.
Eberhard N, Mayer C, Santic R, Navio RP, Wagner A, Bauer HC, Sperk G, Boehm U, Kofler B
Journal of molecular neuroscience : MN46(1)18-32(2012 Jan)

Altered response to metabolic challenges in mice with genetically targeted deletions of galanin-like peptide.
Dungan Lemko HM, Clifton DK, Steiner RA, Fraley GS
American journal of physiology. Endocrinology and metabolism295(3)E605-12(2008 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

we investigated whether PI3K signalling in neurones expressing GALP plays a role in the transcriptional regulation of the GALP gene
Title: Galanin-like peptide (GALP) neurone-specific phosphoinositide 3-kinase signalling regulates GALP mRNA levels in the hypothalamus of males and luteinising hormone levels in both sexes.

results indicate the GALP ICV administration can further promote energy metabolism when administered to spontaneously exercising mice
Title: Interactive effect of galanin-like peptide (GALP) and spontaneous exercise on energy metabolism.

Distinct expression of alarin, a splice variant of GALP, in the adult mouse brain demonstrates potential functions in reproduction and metabolism.
Title: Distribution of alarin immunoreactivity in the mouse brain.

GALP induces expression of IL-1 in the brain, and its anorexic and febrile actions are mediated by this cytokine acting via IL-1 type I receptor.
Title: Interleukin-1 mediates the anorexic and febrile actions of galanin-like Peptide.

GALP may play a role in readjusting energy balance under changing nutritional circumstances
Title: Altered response to metabolic challenges in mice with genetically targeted deletions of galanin-like peptide.

The following Galp gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Galp cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu07122	NM_178028.2 Latest version!	Mus musculus galanin-like peptide (Galp), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OMu07122	XM_006539789.1 Latest version!	Mus musculus galanin-like peptide (Galp), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Galp ( NM_178028.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_821171.1 Mus musculus galanin-like peptide (Galp), mRNA.

Price & Availability↑

CloneID	OMu07122
Clone ID Related Accession (Same CDS sequence)	XM_006539789.1 , NM_178028.2
Accession Version	NM_178028.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 354bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-15
Organism	Mus musculus(house mouse)
Product	galanin-like peptide preproprotein
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AY163546.1. On or before May 4, 2006 this sequence version replaced XM_977913.1, NM_178028.1. ##Evidence-Data-START## Transcript exon combination :: AY163546.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849380, SAMN00849381 [ECO:0000350] ##Evidence-Data-END##

ATGGCCTGCT CCGTACATCT GGTCCTCTTC CTCACCATCT TGCTGAGCCT GGCAGAAACA 
CCGGAATCTG CACCTGCTCA CAGGGGACGA GGAGGCTGGA CCCTCAATAG TGCTGGTTAC 
CTCCTGGGTC CTGTCCTCCC CGTTTCCTCC AAGGCCGACC AGGGCAGGAA GAGAGACTCA 
GCTCTTGAGA TCCTAGACCT GTGGAAGATC ATTGATGGAC TTCCTTATTC CCACTCTCCA 
AGGATGACCA AAAGGACAAT GGGAGAAACG TTTGTCAAAG CGAATACTGG AGATATGCAC 
ATACTGGACA AGAATGTTCC CAAGGAAGAA GCCACCCTGG ACTCAGAGAG TTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_821171.1
CDS	265..618
Translation	MACSVHLVLFLTILLSLAETPESAPAHRGRGGWTLNSAGYLLGPVLPVSSKADQGRKRDSALEILDLWKIIDGLPYSHSPRMTKRTMGETFVKANTGDMHILDKNVPKEEATLDSES

Target ORF information:

RefSeq Version	NM_178028.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus galanin-like peptide (Galp), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_178028.2

ORF Insert Sequence:

ATGGCCTGCT CCGTACATCT GGTCCTCTTC CTCACCATCT TGCTGAGCCT GGCAGAAACA 
CCGGAATCTG CACCTGCTCA CAGGGGACGA GGAGGCTGGA CCCTCAATAG TGCTGGTTAC 
CTCCTGGGTC CTGTCCTCCC CGTTTCCTCC AAGGCCGACC AGGGCAGGAA GAGAGACTCA 
GCTCTTGAGA TCCTAGACCT GTGGAAGATC ATTGATGGAC TTCCTTATTC CCACTCTCCA 
AGGATGACCA AAAGGACAAT GGGAGAAACG TTTGTCAAAG CGAATACTGG AGATATGCAC 
ATACTGGACA AGAATGTTCC CAAGGAAGAA GCCACCCTGG ACTCAGAGAG TTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Galp ( XM_006539789.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006539852.1 Mus musculus galanin-like peptide (Galp), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu07122
Clone ID Related Accession (Same CDS sequence)	XM_006539789.1 , NM_178028.2
Accession Version	XM_006539789.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 354bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	galanin-like peptide isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCTGCT CCGTACATCT GGTCCTCTTC CTCACCATCT TGCTGAGCCT GGCAGAAACA 
CCGGAATCTG CACCTGCTCA CAGGGGACGA GGAGGCTGGA CCCTCAATAG TGCTGGTTAC 
CTCCTGGGTC CTGTCCTCCC CGTTTCCTCC AAGGCCGACC AGGGCAGGAA GAGAGACTCA 
GCTCTTGAGA TCCTAGACCT GTGGAAGATC ATTGATGGAC TTCCTTATTC CCACTCTCCA 
AGGATGACCA AAAGGACAAT GGGAGAAACG TTTGTCAAAG CGAATACTGG AGATATGCAC 
ATACTGGACA AGAATGTTCC CAAGGAAGAA GCCACCCTGG ACTCAGAGAG TTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006539852.1
CDS	196..549
Translation	MACSVHLVLFLTILLSLAETPESAPAHRGRGGWTLNSAGYLLGPVLPVSSKADQGRKRDSALEILDLWKIIDGLPYSHSPRMTKRTMGETFVKANTGDMHILDKNVPKEEATLDSES

Target ORF information:

RefSeq Version	XM_006539789.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus galanin-like peptide (Galp), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006539789.1

ORF Insert Sequence:

ATGGCCTGCT CCGTACATCT GGTCCTCTTC CTCACCATCT TGCTGAGCCT GGCAGAAACA 
CCGGAATCTG CACCTGCTCA CAGGGGACGA GGAGGCTGGA CCCTCAATAG TGCTGGTTAC 
CTCCTGGGTC CTGTCCTCCC CGTTTCCTCC AAGGCCGACC AGGGCAGGAA GAGAGACTCA 
GCTCTTGAGA TCCTAGACCT GTGGAAGATC ATTGATGGAC TTCCTTATTC CCACTCTCCA 
AGGATGACCA AAAGGACAAT GGGAGAAACG TTTGTCAAAG CGAATACTGG AGATATGCAC 
ATACTGGACA AGAATGTTCC CAAGGAAGAA GCCACCCTGG ACTCAGAGAG TTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Anti-obesity effect of intranasal administration of galanin-like peptide (GALP) in obese mice.
Scientific reports628200(2016 Jun)
Kageyama H,Shiba K,Hirako S,Wada N,Yamanaka S,Nogi Y,Takenoya F,Nonaka N,Hirano T,Inoue S,Shioda S

Galanin-like peptide (GALP) neurone-specific phosphoinositide 3-kinase signalling regulates GALP mRNA levels in the hypothalamus of males and luteinising hormone levels in both sexes.
Journal of neuroendocrinology26(7)426-38(2014 Jul)
Aziz R,Beymer M,Negr?n AL,Newshan A,Yu G,Rosati B,McKinnon D,Fukuda M,Lin RZ,Mayer C,Boehm U,Acosta-Mart?nez M

Interactive effect of galanin-like peptide (GALP) and spontaneous exercise on energy metabolism.
Peptides49109-16(2013 Nov)
Ito K,Kageyama H,Hirako S,Wang L,Takenoya F,Ogawa T,Shioda S

Distribution of alarin immunoreactivity in the mouse brain.
Journal of molecular neuroscience : MN46(1)18-32(2012 Jan)
Eberhard N,Mayer C,Santic R,Navio RP,Wagner A,Bauer HC,Sperk G,Boehm U,Kofler B

Altered response to metabolic challenges in mice with genetically targeted deletions of galanin-like peptide.
American journal of physiology. Endocrinology and metabolism295(3)E605-12(2008 Sep)
Dungan Lemko HM,Clifton DK,Steiner RA,Fraley GS

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Galp cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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