Uts2r cDNA ORF clone, Mus musculus(house mouse)

The role of urotensin-II and its receptors in sepsis-induced lung injury under diabetic conditions.
Ugan RA, Cadirci E, Halici Z, Toktay E, Cinar I
European journal of pharmacology818457-469(2018 Jan)

Renal Urotensin II System Plays Roles in the Regulation of Blood Pressure in Dahl Salt-Resistant Rat.
Wu F, Chen G, Zhang A, Yu Y, Fan M, Tang C
International journal of hypertension20169146870(2016)

Blocking the urotensin II receptor pathway ameliorates the metabolic syndrome and improves cardiac function in obese mice.
You Z, Al Kindi H, Abdul-Karim A, Barrette PO, Schwertani A
FASEB journal : official publication of the Federation of American Societies for Experimental Biology28(3)1210-20(2014 Mar)

Inhibition of UII/UTR system relieves acute inflammation of liver through preventing activation of NF-?B pathway in ALF mice.
Liang DY, Liu LM, Ye CG, Zhao L, Yu FP, Gao DY, Wang YY, Yang ZW, Wang YY
PloS one8(6)e64895(2014)

findings demonstrate an important role for UII in the pathogenesis of the metabolic syndrome and suggest that the use of UT receptor antagonists may provide a new therapeutic tool for the treatment of this syndrome
Title: Blocking the urotensin II receptor pathway ameliorates the metabolic syndrome and improves cardiac function in obese mice.

UII/UTR system plays a role in lipopolysaccharide (LPS)/D-galactosamine (GalN)-induced acute liver failure.
Title: Inhibition of UII/UTR system relieves acute inflammation of liver through preventing activation of NF-?B pathway in ALF mice.

a new urotensin II receptor signalling pathway which is mediated by EGFR trans-activation, dependent by beta-arrestin 1/2, promoting cell survival and cardioprotection.
Title: EGFR trans-activation by urotensin II receptor is mediated by ?-arrestin recruitment and confers cardioprotection in pressure overload-induced cardiac hypertrophy.

In addition to its role at the neuromuscular junction, urotensin II may control motor function through the modulation of motoneuron activity within the spinal cord.
Title: Urotensin II receptor and acetylcholine release from mouse cervical spinal cord nerve terminals.

Urotensin II receptor knockout mice on an ApoE knockout background fed a high-fat diet exhibit an enhanced hyperlipidemic and atherosclerotic phenotype.
Title: Urotensin II receptor knockout mice on an ApoE knockout background fed a high-fat diet exhibit an enhanced hyperlipidemic and atherosclerotic phenotype.