ABCC8 cDNA ORF clone, Mus musculus(House mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	ABCC8
Entrez Gene ID	20927
Full Name	ATP-binding cassette, sub-family C (CFTR/MRP), member 8
Synonyms	D930031B21Rik,SUR1,Sur
General protein information	Preferred Names ATP-binding cassette, sub-family C (CFTR/MRP), member 8 Names ATP-binding cassette sub-family C member 8 sulfonylurea receptor
Gene Type	protein-coding
Organism	Mus musculus(House mouse)
Genome	Chromosome: 7 Map Location: 7 B3\|7 29.66 cM

mRNA and Protein(s)

mRNA	Protein	Name
XM_006540749.1	XP_006540812.1	ATP-binding cassette sub-family C member 8 isoform X1
NM_001357538.1	NP_001344467.1	ATP-binding cassette sub-family C member 8 isoform 2
NM_011510.3	NP_035640.2	ATP-binding cassette sub-family C member 8 isoform 1
XM_030242316.1	XP_030098176.1	ATP-binding cassette sub-family C member 8 isoform X2
XM_006540750.1	XP_006540813.1	ATP-binding cassette sub-family C member 8 isoform X2

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Abcc8	NP_035640.2
Gallus gallus (chicken)	ABCC8	XP_421005.2
Pan troglodytes (chimpanzee)	ABCC8	XP_508310.4
	ABCC8	XP_001088694.1
Canis lupus familiaris (dog)	ABCC8	XP_005633781.1
Bos taurus (cattle)	ABCC8	NP_001192539.1
Rattus norvegicus (Norway rat)	Abcc8	NP_037171.2
Danio rerio (zebrafish)	abcc8	NP_001166118.2
Homo sapiens (human)	ABCC8	NP_001274103.1

Gene Ontology
Bibliography

Related articles in PubMed

Role of osteopontin and its regulation in pancreatic islet.
Cai M, Bompada P, Salehi A, Acosta JR, Prasad RB, Atac D, Laakso M, Groop L, De Marinis Y
Biochemical and biophysical research communications495(1)1426-1431(2018 01)

SUR1-TRPM4 and AQP4 form a heteromultimeric complex that amplifies ion/water osmotic coupling and drives astrocyte swelling.
Stokum JA, Kwon MS, Woo SK, Tsymbalyuk O, Vennekens R, Gerzanich V, Simard JM
Glia66(1)108-125(2018 Jan)

Chronic ?-Cell Depolarization Impairs ?-Cell Identity by Disrupting a Network of Ca
Stancill JS, Cartailler JP, Clayton HW, O'Connor JT, Dickerson MT, Dadi PK, Osipovich AB, Jacobson DA, Magnuson MA
Diabetes66(8)2175-2187(2017 08)

Distinct roles for the mTOR pathway in postnatal morphogenesis, maturation and function of pancreatic islets.
Sinagoga KL, Stone WJ, Schiesser JV, Schweitzer JI, Sampson L, Zheng Y, Wells JM
Development (Cambridge, England)144(13)2402-2414(2017 07)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Despite its importance in central nervous system (CNS) injuries, sulfonylurea receptor 1 (SUR1) upregulation appears to play no part in rodent anterior ischemic optic neuropathy (rAION) injury.
Title: SUR1-Associated Mechanisms Are Not Involved in Ischemic Optic Neuropathy 1 Day Post-Injury.

study provides evidence for a role of Abcc8(ATP-binding cassette sub-family C) in early-phase glucose-mediated insulin secretion and validates this gene as a contributor to beta-cell dysfunction in type 2 diabetes
Title: Identification of ABCC8 as a contributory gene to impaired early-phase insulin secretion in NZO mice.

We conclude that the gradual development of glucose intolerance in patients with the SUR1-E1506K mutation might, as in the mouse model, result from impaired insulin secretion due a failure of insulin content to increase with age.
Title: A mouse model of human hyperinsulinism produced by the E1506K mutation in the sulphonylurea receptor SUR1.

The results confirm that Kir6.2 contributes to APD shortening in both atria and ventricle during metabolic stress, and that SUR1 is required for atrial APD shortening while SUR2A is required for ventricular APD shortening.
Title: Functional roles of KATP channel subunits in metabolic inhibition.

EPAC interaction with SUR1 controls seizure susceptibility and possibly acts via regulation of glutamate release.
Title: EPAC inhibition of SUR1 receptor increases glutamate release and seizure vulnerability.

The following ABCC8 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ABCC8 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu68823	XM_030242316.1 Latest version!	Mus musculus ATP-binding cassette, sub-family C (CFTR/MRP), member 8 (Abcc8), transcript variant X7, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$727.30 $1039.00
OMu08305	NM_011510.3 Latest version!	Mus musculus ATP-binding cassette, sub-family C (CFTR/MRP), member 8 (Abcc8), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	22	$811.30 $1159.00
OMu38750	NM_001357538.1 Latest version!	Mus musculus ATP-binding cassette, sub-family C (CFTR/MRP), member 8 (Abcc8), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$811.30 $1159.00
OMu38749	XM_006540749.1 Latest version!	Mus musculus ATP-binding cassette, sub-family C (CFTR/MRP), member 8 (Abcc8), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$811.30 $1159.00
OMu38750	XM_006540750.1 Latest version!	Mus musculus ATP-binding cassette, sub-family C (CFTR/MRP), member 8 (Abcc8), transcript variant X5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$811.30 $1159.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ABCC8 ( XM_030242316.1 ) cDNA ORF clone, Mus musculus(House mouse) -> XP_030098176.1 Mus musculus ATP-binding cassette, sub-family C (CFTR/MRP), member 8 (Abcc8), transcript variant X7, mRNA.

Price & Availability↑

CloneID	OMu68823
Clone ID Related Accession (Same CDS sequence)	XM_030242316.1
Accession Version	XM_030242316.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4089bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	ATP-binding cassette sub-family C member 8 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCCTTGG CCTTCTGCGG CACCGAGAAC CACTCGGCCG CCTACCGGGT GGACCAAGGT 
GTCCTCAACA ACGGCTGCTT CGTGGACGCG CTCAACGTAG TGCCACATGT CTTCCTGCTC 
TTCATCACAT TCCCCATCCT CTTCATCGGA TGGGGCAGCC AGAGCTCCAA GGTACACATT 
CACCATAGCA CCTGGCTCCA TTTCCCTGGC CACAACCTGC GCTGGATCCT TACCTTCATG 
CTGCTCTTTG TCCTGGTGTG TGAGATCGCT GAGGGTATCC TGTCTGATGG GGTGACAGAA 
TCCCGCCACC TCCATTTGTA CATGCCAGCT GGGATGGCTT TCATGGCTGC CATCACCTCT 
GTGGTCTACT ATCACAACAT TGAGACCTCT AACTTCCCCA AGCTGCTGAT CGCTCTGCTT 
ATCTACTGGA CCTTGGCCTT CATCACTAAG ACCATCAAGT TCGTCAAGTT CTACGACCAC 
GCCATCGGCT TCTCTCAGCT GCGCTTCTGC CTCACGGGGC TTCTGGTGAT CCTCTACGGG 
ATGCTGCTGC TGGTGGAGAT CAATGTCATC CGGGTGCGGA GGTACATCTT CTTCAAGACG 
CCAAGGGAAG TGAAGCCCCC TGAGGACCTG CAGGACCTGG GGGTGCGCTT TCTGCAGCCC 
TTCGTGAATC TGCTGTCAAA GGGGACCTAC TGGTGGATGA ATGCCTTCAT CAAGACTGCC 
CACAGGAAGC CCATCGACCT GCGGGCCATC GGGAAGCTGC CCATCGCCAT GAGAGCCCTC 
ACCAACTATC AGCGACTCTG CGCGGCCTTC GATGCCCAGG CGCGGAAAGA CACGCAGAGC 
CAGCAGGGCG CCCGGGCCAT CTGGAGGGCT CTCTGCCATG CCTTTGGGAG ACGCCTGGTC 
CTCAGCAGCA CATTCCGTAT CCTGGCTGAC CTGCTGGGCT TTGCTGGACC GCTCTGCATC 
TTTGGGATCG TGGACCACCT CGGGAAGGAG AACCATGTCT TCCAGCCCAA GACACAGTTT 
CTTGGGGTTT ACTTTGTCTC GTCCCAAGAG TTCCTGGGCA ACGCCTATGT CTTGGCTGTA 
CTTCTGTTCC TGGCCCTCCT GCTGCAAAGG ACGTTCCTGC AAGCCTCGTA CTACGTCGCC 
ATTGAAACTG GGATTAACCT GAGAGGGGCG ATCCAGACCA AGATTTACAA TAAGATCATG 
CACTTGTCTA CTTCCAACCT GTCAATGGGG GAGATGACGG CTGGGCAGAT CTGCAACCTG 
GTGGCCATCG ACACAAATCA GCTCATGTGG TTTTTCTTCT TATGCCCAAA CCTCTGGGCT 
ATGCCAGTAC AGATCATTGT GGGCGTGATC CTCCTCTACT ACATCCTTGG GGTCAGTGCC 
TTGATTGGAG CAGCTGTCAT CATTCTGCTG GCTCCTGTAC AGTACTTTGT GGCCACCAAG 
CTCTCCCAGG CACAGCGGAG CACCCTGGAA TATTCCAATG AAAGGCTGAA GCAGACCAAC 
GAGATGCTCC GGGGCATCAA ACTGCTCAAA CTGTACGCGT GGGAGAACAT CTTCTGCTCG 
AGGGTGGAGA TGACGCGCAG GAAGGAAATG ACCAGCCTCA GAGCCTTCGC TGTCTACACC 
TCCATCTCCA TCTTCATGAA CACAGCTATC CCCATTGCTG CCGTCCTCAT TACCTTTGTG 
GGCCACGTCA GCTTCTTCAA AGAGTCAGAC TTCTCACCCT CGGTGGCCTT TGCCTCTCTC 
TCTCTCTTCC ACATCCTGGT CACACCGCTG TTCCTGCTGT CTAGTGTGGT TCGGTCCACC 
GTCAAGGCCC TAGTGAGTGT GCAAAAGCTG AGTGAGTTCC TGTCCAGTGC AGAGATCCGT 
GAGGAACAGT GTGCCCCCCG AGAGCCTGCA CCCCAAGGCC AAGCGGGCAA GTACCAGGCG 
GTGCCCCTCA AGGTTGTGAA CCGCAAGCGC CCAGCCCGGG AAGAGGTTCG GGACCTCTTG 
GGCCCACTGC AGAGGCTGAC CCCCAGCATG GATGGAGATG CTGACAACTT CTGTGTCCAG 
ATCATCGGAG GCTTCTTCAC CTGGACCCCT GATGGAATCC CCACCCTGTC CAACATCACC 
ATCCGTATCC CCCGAGGCCA GCTGACCATG ATTGTGGGGC AGGTGGGCTG CGGCAAGTCC 
TCGCTCCTTC TGGCCACCCT GGGGGAGATG CAGAGGGTCT CCGGGGCCGT CTTCTGGAAC 
AGCAGCCTTC CAGACAGCGA GGGAGAAGAC CCCAGGTATT GCCTCAGGAC AAGCAACCCA 
GAGCGGGAGA CAGCAGCCGA CTCGGATGCC AGGAGCAGAG GCCCCGTAGC CTACGCATCT 
CAGAAACCAT GGCTGCTAAA TGCCACGGTG GAGGAGAACA TCACCTTCGA GAGTCCCTTC 
AATAAGCAAA GGTACAAGAT GGTCATCGAA GCCTGCTCCC TGCAGCCAGA CATAGACATC 
TTACCCCATG GAGACCAGAC TCAGATTGGG GAACGGGGCA TCAACTTGTC TGGTGGTCAG 
CGTCAGCGAA TCAGTGTAGC CCGAGCCCTC TACCAGCACA CCAATGTTGT CTTCTTGGAT 
GACCCTTTCT CAGCTCTGGA TGTCCATCTG AGCGACCACC TGATGCAGGC TGGCATCCTT 
GAGCTGCTCC GGGATGACAA GAGGACAGTG GTCTTGGTGA CCCACAAGCT ACAGTACCTG 
CCTCATGCAG ACTGGATCAT TGCTATGAAG GATGGCACCA TTCAGAGGGA GGGGACGCTC 
AAGGACTTCC AGAGGTCTGA GTGCCAGCTC TTTGAGCATT GGAAGACCCT CATGAACAGG 
CAAGACCAAG AGCTGGAGAA GGAGACAGTC ATGGAGAGGA AAGCCCCAGA ACCGTCTCAG 
GGCCTGCCCC GTGCCATGTC CTCAAGAGAT GGCCTTCTGC TGGATGAGGA CGAGGAGGAA 
GAGGAGGCGG CCGAGAGCGA GGAAGATGAC AACTTATCTT CGGTGCTGCA TCAGCGAGCC 
AAGATCCCAT GGCGGGCCTG CACTAAGTAT TTGTCCTCTG CCGGCGTCCT GCTCTTGTCC 
CTGCTTGTCT TCTCCCAGCT ACTCAAGCAC ATGGTCTTGG TGGCCATTGA TTACTGGCTG 
GCCAAGTGGA CGGACAGTGC CCTGGTCCTG AGCCCTGCTG CCAGGAACTG CTCCCTCAGC 
CAGGAATGCG CCCTGGACCA GTCTGTCTAT GCCATGGTAT TCACCGTGCT CTGCAGCCTG 
GGAATTGCAC TGTGCCTTGT CACCTCTGTC ACTGTGGAGT GGACAGGACT GAAGGTGGCC 
AAGAGGCTGC ACCGCAGCCT GCTCAATCGC ATCATCCTGG CCCCCATGAG GTTCTTTGAG 
ACCACGCCCC TGGGGAGTAT CCTGAACAGA TTTTCATCTG ACTGTAACAC CATTGACCAG 
CACATCCCAT CCACGCTGGA GTGTCTGAGC CGATCCACTC TACTCTGTGT CTCCGCCTTG 
ACTGTCATCT CCTACGTCAC ACCTGTGTTC CTCGTGGCCC TCTTACCCCT AGCTGTGGTG 
TGCTACTTCA TCCAGAAATA CTTCCGAGTG GCGTCCAGGG ACCTGCAGCA GCTGGATGAC 
ACAACGCAGC TCCCTCTGCT CTCACACTTT GCTGAAACCG TGGAAGGACT CACCACCATC 
CGTGCCTTCA GGTACGAGGC CCGGTTCCAG CAGAAGCTCC TGGAGTACAC GGACTCCAAC 
AACATCGCCT CCCTCTTCCT CACGGCAGCC AACAGGTGGC TAGAAGTCCG CATGCCCGGG 
CCAGCTGCTG TCCTTCCTCA GGAGTACATT GGAGCATGCG TGGTACTCAT CGCAGCCGCC 
ACCTCCATCT CCAACTCCCT GCACAGGGAG CTCTCTGCTG GTCTGGTGGG CCTGGGCCTC 
ACCTACGCCT TGATGGTCTC CAACTACCTC AACTGGATGG TGAGGAACCT GGCAGACATG 
GAGATCCAAT TGGGGGCTGT GAAGCGCATC CACACACTCC TGAAAACTGA GGCAGAGAGC 
TATGAGGGGC TCCTAGAACT GGCCAGACCA AGGGAAGATT CAAATTCAAA ACCTGAGTGT 
GCGCTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_030098176.1
CDS	91..4179
Translation	MPLAFCGTENHSAAYRVDQGVLNNGCFVDALNVVPHVFLLFITFPILFIGWGSQSSKVHIHHSTWLHFPGHNLRWILTFMLLFVLVCEIAEGILSDGVTESRHLHLYMPAGMAFMAAITSVVYYHNIETSNFPKLLIALLIYWTLAFITKTIKFVKFYDHAIGFSQLRFCLTGLLVILYGMLLLVEINVIRVRRYIFFKTPREVKPPEDLQDLGVRFLQPFVNLLSKGTYWWMNAFIKTAHRKPIDLRAIGKLPIAMRALTNYQRLCAAFDAQARKDTQSQQGARAIWRALCHAFGRRLVLSSTFRILADLLGFAGPLCIFGIVDHLGKENHVFQPKTQFLGVYFVSSQEFLGNAYVLAVLLFLALLLQRTFLQASYYVAIETGINLRGAIQTKIYNKIMHLSTSNLSMGEMTAGQICNLVAIDTNQLMWFFFLCPNLWAMPVQIIVGVILLYYILGVSALIGAAVIILLAPVQYFVATKLSQAQRSTLEYSNERLKQTNEMLRGIKLLKLYAWENIFCSRVEMTRRKEMTSLRAFAVYTSISIFMNTAIPIAAVLITFVGHVSFFKESDFSPSVAFASLSLFHILVTPLFLLSSVVRSTVKALVSVQKLSEFLSSAEIREEQCAPREPAPQGQAGKYQAVPLKVVNRKRPAREEVRDLLGPLQRLTPSMDGDADNFCVQIIGGFFTWTPDGIPTLSNITIRIPRGQLTMIVGQVGCGKSSLLLATLGEMQRVSGAVFWNSSLPDSEGEDPRYCLRTSNPERETAADSDARSRGPVAYASQKPWLLNATVEENITFESPFNKQRYKMVIEACSLQPDIDILPHGDQTQIGERGINLSGGQRQRISVARALYQHTNVVFLDDPFSALDVHLSDHLMQAGILELLRDDKRTVVLVTHKLQYLPHADWIIAMKDGTIQREGTLKDFQRSECQLFEHWKTLMNRQDQELEKETVMERKAPEPSQGLPRAMSSRDGLLLDEDEEEEEAAESEEDDNLSSVLHQRAKIPWRACTKYLSSAGVLLLSLLVFSQLLKHMVLVAIDYWLAKWTDSALVLSPAARNCSLSQECALDQSVYAMVFTVLCSLGIALCLVTSVTVEWTGLKVAKRLHRSLLNRIILAPMRFFETTPLGSILNRFSSDCNTIDQHIPSTLECLSRSTLLCVSALTVISYVTPVFLVALLPLAVVCYFIQKYFRVASRDLQQLDDTTQLPLLSHFAETVEGLTTIRAFRYEARFQQKLLEYTDSNNIASLFLTAANRWLEVRMPGPAAVLPQEYIGACVVLIAAATSISNSLHRELSAGLVGLGLTYALMVSNYLNWMVRNLADMEIQLGAVKRIHTLLKTEAESYEGLLELARPREDSNSKPECAL

Target ORF information:

RefSeq Version	XM_030242316.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus ATP-binding cassette, sub-family C (CFTR/MRP), member 8 (Abcc8), transcript variant X7, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_030242316.1

ORF Insert Sequence:

ATGCCCTTGG CCTTCTGCGG CACCGAGAAC CACTCGGCCG CCTACCGGGT GGACCAAGGT 
GTCCTCAACA ACGGCTGCTT CGTGGACGCG CTCAACGTAG TGCCACATGT CTTCCTGCTC 
TTCATCACAT TCCCCATCCT CTTCATCGGA TGGGGCAGCC AGAGCTCCAA GGTACACATT 
CACCATAGCA CCTGGCTCCA TTTCCCTGGC CACAACCTGC GCTGGATCCT TACCTTCATG 
CTGCTCTTTG TCCTGGTGTG TGAGATCGCT GAGGGTATCC TGTCTGATGG GGTGACAGAA 
TCCCGCCACC TCCATTTGTA CATGCCAGCT GGGATGGCTT TCATGGCTGC CATCACCTCT 
GTGGTCTACT ATCACAACAT TGAGACCTCT AACTTCCCCA AGCTGCTGAT CGCTCTGCTT 
ATCTACTGGA CCTTGGCCTT CATCACTAAG ACCATCAAGT TCGTCAAGTT CTACGACCAC 
GCCATCGGCT TCTCTCAGCT GCGCTTCTGC CTCACGGGGC TTCTGGTGAT CCTCTACGGG 
ATGCTGCTGC TGGTGGAGAT CAATGTCATC CGGGTGCGGA GGTACATCTT CTTCAAGACG 
CCAAGGGAAG TGAAGCCCCC TGAGGACCTG CAGGACCTGG GGGTGCGCTT TCTGCAGCCC 
TTCGTGAATC TGCTGTCAAA GGGGACCTAC TGGTGGATGA ATGCCTTCAT CAAGACTGCC 
CACAGGAAGC CCATCGACCT GCGGGCCATC GGGAAGCTGC CCATCGCCAT GAGAGCCCTC 
ACCAACTATC AGCGACTCTG CGCGGCCTTC GATGCCCAGG CGCGGAAAGA CACGCAGAGC 
CAGCAGGGCG CCCGGGCCAT CTGGAGGGCT CTCTGCCATG CCTTTGGGAG ACGCCTGGTC 
CTCAGCAGCA CATTCCGTAT CCTGGCTGAC CTGCTGGGCT TTGCTGGACC GCTCTGCATC 
TTTGGGATCG TGGACCACCT CGGGAAGGAG AACCATGTCT TCCAGCCCAA GACACAGTTT 
CTTGGGGTTT ACTTTGTCTC GTCCCAAGAG TTCCTGGGCA ACGCCTATGT CTTGGCTGTA 
CTTCTGTTCC TGGCCCTCCT GCTGCAAAGG ACGTTCCTGC AAGCCTCGTA CTACGTCGCC 
ATTGAAACTG GGATTAACCT GAGAGGGGCG ATCCAGACCA AGATTTACAA TAAGATCATG 
CACTTGTCTA CTTCCAACCT GTCAATGGGG GAGATGACGG CTGGGCAGAT CTGCAACCTG 
GTGGCCATCG ACACAAATCA GCTCATGTGG TTTTTCTTCT TATGCCCAAA CCTCTGGGCT 
ATGCCAGTAC AGATCATTGT GGGCGTGATC CTCCTCTACT ACATCCTTGG GGTCAGTGCC 
TTGATTGGAG CAGCTGTCAT CATTCTGCTG GCTCCTGTAC AGTACTTTGT GGCCACCAAG 
CTCTCCCAGG CACAGCGGAG CACCCTGGAA TATTCCAATG AAAGGCTGAA GCAGACCAAC 
GAGATGCTCC GGGGCATCAA ACTGCTCAAA CTGTACGCGT GGGAGAACAT CTTCTGCTCG 
AGGGTGGAGA TGACGCGCAG GAAGGAAATG ACCAGCCTCA GAGCCTTCGC TGTCTACACC 
TCCATCTCCA TCTTCATGAA CACAGCTATC CCCATTGCTG CCGTCCTCAT TACCTTTGTG 
GGCCACGTCA GCTTCTTCAA AGAGTCAGAC TTCTCACCCT CGGTGGCCTT TGCCTCTCTC 
TCTCTCTTCC ACATCCTGGT CACACCGCTG TTCCTGCTGT CTAGTGTGGT TCGGTCCACC 
GTCAAGGCCC TAGTGAGTGT GCAAAAGCTG AGTGAGTTCC TGTCCAGTGC AGAGATCCGT 
GAGGAACAGT GTGCCCCCCG AGAGCCTGCA CCCCAAGGCC AAGCGGGCAA GTACCAGGCG 
GTGCCCCTCA AGGTTGTGAA CCGCAAGCGC CCAGCCCGGG AAGAGGTTCG GGACCTCTTG 
GGCCCACTGC AGAGGCTGAC CCCCAGCATG GATGGAGATG CTGACAACTT CTGTGTCCAG 
ATCATCGGAG GCTTCTTCAC CTGGACCCCT GATGGAATCC CCACCCTGTC CAACATCACC 
ATCCGTATCC CCCGAGGCCA GCTGACCATG ATTGTGGGGC AGGTGGGCTG CGGCAAGTCC 
TCGCTCCTTC TGGCCACCCT GGGGGAGATG CAGAGGGTCT CCGGGGCCGT CTTCTGGAAC 
AGCAGCCTTC CAGACAGCGA GGGAGAAGAC CCCAGGTATT GCCTCAGGAC AAGCAACCCA 
GAGCGGGAGA CAGCAGCCGA CTCGGATGCC AGGAGCAGAG GCCCCGTAGC CTACGCATCT 
CAGAAACCAT GGCTGCTAAA TGCCACGGTG GAGGAGAACA TCACCTTCGA GAGTCCCTTC 
AATAAGCAAA GGTACAAGAT GGTCATCGAA GCCTGCTCCC TGCAGCCAGA CATAGACATC 
TTACCCCATG GAGACCAGAC TCAGATTGGG GAACGGGGCA TCAACTTGTC TGGTGGTCAG 
CGTCAGCGAA TCAGTGTAGC CCGAGCCCTC TACCAGCACA CCAATGTTGT CTTCTTGGAT 
GACCCTTTCT CAGCTCTGGA TGTCCATCTG AGCGACCACC TGATGCAGGC TGGCATCCTT 
GAGCTGCTCC GGGATGACAA GAGGACAGTG GTCTTGGTGA CCCACAAGCT ACAGTACCTG 
CCTCATGCAG ACTGGATCAT TGCTATGAAG GATGGCACCA TTCAGAGGGA GGGGACGCTC 
AAGGACTTCC AGAGGTCTGA GTGCCAGCTC TTTGAGCATT GGAAGACCCT CATGAACAGG 
CAAGACCAAG AGCTGGAGAA GGAGACAGTC ATGGAGAGGA AAGCCCCAGA ACCGTCTCAG 
GGCCTGCCCC GTGCCATGTC CTCAAGAGAT GGCCTTCTGC TGGATGAGGA CGAGGAGGAA 
GAGGAGGCGG CCGAGAGCGA GGAAGATGAC AACTTATCTT CGGTGCTGCA TCAGCGAGCC 
AAGATCCCAT GGCGGGCCTG CACTAAGTAT TTGTCCTCTG CCGGCGTCCT GCTCTTGTCC 
CTGCTTGTCT TCTCCCAGCT ACTCAAGCAC ATGGTCTTGG TGGCCATTGA TTACTGGCTG 
GCCAAGTGGA CGGACAGTGC CCTGGTCCTG AGCCCTGCTG CCAGGAACTG CTCCCTCAGC 
CAGGAATGCG CCCTGGACCA GTCTGTCTAT GCCATGGTAT TCACCGTGCT CTGCAGCCTG 
GGAATTGCAC TGTGCCTTGT CACCTCTGTC ACTGTGGAGT GGACAGGACT GAAGGTGGCC 
AAGAGGCTGC ACCGCAGCCT GCTCAATCGC ATCATCCTGG CCCCCATGAG GTTCTTTGAG 
ACCACGCCCC TGGGGAGTAT CCTGAACAGA TTTTCATCTG ACTGTAACAC CATTGACCAG 
CACATCCCAT CCACGCTGGA GTGTCTGAGC CGATCCACTC TACTCTGTGT CTCCGCCTTG 
ACTGTCATCT CCTACGTCAC ACCTGTGTTC CTCGTGGCCC TCTTACCCCT AGCTGTGGTG 
TGCTACTTCA TCCAGAAATA CTTCCGAGTG GCGTCCAGGG ACCTGCAGCA GCTGGATGAC 
ACAACGCAGC TCCCTCTGCT CTCACACTTT GCTGAAACCG TGGAAGGACT CACCACCATC 
CGTGCCTTCA GGTACGAGGC CCGGTTCCAG CAGAAGCTCC TGGAGTACAC GGACTCCAAC 
AACATCGCCT CCCTCTTCCT CACGGCAGCC AACAGGTGGC TAGAAGTCCG CATGCCCGGG 
CCAGCTGCTG TCCTTCCTCA GGAGTACATT GGAGCATGCG TGGTACTCAT CGCAGCCGCC 
ACCTCCATCT CCAACTCCCT GCACAGGGAG CTCTCTGCTG GTCTGGTGGG CCTGGGCCTC 
ACCTACGCCT TGATGGTCTC CAACTACCTC AACTGGATGG TGAGGAACCT GGCAGACATG 
GAGATCCAAT TGGGGGCTGT GAAGCGCATC CACACACTCC TGAAAACTGA GGCAGAGAGC 
TATGAGGGGC TCCTAGAACT GGCCAGACCA AGGGAAGATT CAAATTCAAA ACCTGAGTGT 
GCGCTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ABCC8 ( NM_011510.3 ) cDNA ORF clone, Mus musculus(House mouse) -> NP_035640.2 Mus musculus ATP-binding cassette, sub-family C (CFTR/MRP), member 8 (Abcc8), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu08305
Clone ID Related Accession (Same CDS sequence)	NM_011510.3
Accession Version	NM_011510.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4767bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-22
Organism	Mus musculus(house mouse)
Product	ATP-binding cassette sub-family C member 8 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC120135.7 and AC115036.10. On Nov 17, 2006 this sequence version replaced NM_011510.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC141411.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCCTTGG CCTTCTGCGG CACCGAGAAC CACTCGGCCG CCTACCGGGT GGACCAAGGT 
GTCCTCAACA ACGGCTGCTT CGTGGACGCG CTCAACGTAG TGCCACATGT CTTCCTGCTC 
TTCATCACAT TCCCCATCCT CTTCATCGGA TGGGGCAGCC AGAGCTCCAA GGTACACATT 
CACCATAGCA CCTGGCTCCA TTTCCCTGGC CACAACCTGC GCTGGATCCT TACCTTCATG 
CTGCTCTTTG TCCTGGTGTG TGAGATCGCT GAGGGTATCC TGTCTGATGG GGTGACAGAA 
TCCCGCCACC TCCATTTGTA CATGCCAGCT GGGATGGCTT TCATGGCTGC CATCACCTCT 
GTGGTCTACT ATCACAACAT TGAGACCTCT AACTTCCCCA AGCTGCTGAT CGCTCTGCTT 
ATCTACTGGA CCTTGGCCTT CATCACTAAG ACCATCAAGT TCGTCAAGTT CTACGACCAC 
GCCATCGGCT TCTCTCAGCT GCGCTTCTGC CTCACGGGGC TTCTGGTGAT CCTCTACGGG 
ATGCTGCTGC TGGTGGAGAT CAATGTCATC CGGGTGCGGA GGTACATCTT CTTCAAGACG 
CCAAGGGAAG TGAAGCCCCC TGAGGACCTG CAGGACCTGG GGGTGCGCTT TCTGCAGCCC 
TTCGTGAATC TGCTGTCAAA GGGGACCTAC TGGTGGATGA ATGCCTTCAT CAAGACTGCC 
CACAGGAAGC CCATCGACCT GCGGGCCATC GGGAAGCTGC CCATCGCCAT GAGAGCCCTC 
ACCAACTATC AGCGACTCTG CGCGGCCTTC GATGCCCAGG CGCGGAAAGA CACGCAGAGC 
CAGCAGGGCG CCCGGGCCAT CTGGAGGGCT CTCTGCCATG CCTTTGGGAG ACGCCTGGTC 
CTCAGCAGCA CATTCCGTAT CCTGGCTGAC CTGCTGGGCT TTGCTGGACC GCTCTGCATC 
TTTGGGATCG TGGACCACCT CGGGAAGGAG AACCATGTCT TCCAGCCCAA GACACAGTTT 
CTTGGGGTTT ACTTTGTCTC GTCCCAAGAG TTCCTGGGCA ACGCCTATGT CTTGGCTGTA 
CTTCTGTTCC TGGCCCTCCT GCTGCAAAGG ACGTTCCTGC AAGCCTCGTA CTACGTCGCC 
ATTGAAACTG GGATTAACCT GAGAGGGGCG ATCCAGACCA AGATTTACAA TAAGATCATG 
CACTTGTCTA CTTCCAACCT GTCAATGGGG GAGATGACGG CTGGGCAGAT CTGCAACCTG 
GTGGCCATCG ACACAAATCA GCTCATGTGG TTTTTCTTCT TATGCCCAAA CCTCTGGGCT 
ATGCCAGTAC AGATCATTGT GGGCGTGATC CTCCTCTACT ACATCCTTGG GGTCAGTGCC 
TTGATTGGAG CAGCTGTCAT CATTCTGCTG GCTCCTGTAC AGTACTTTGT GGCCACCAAG 
CTCTCCCAGG CACAGCGGAG CACCCTGGAA TATTCCAATG AAAGGCTGAA GCAGACCAAC 
GAGATGCTCC GGGGCATCAA ACTGCTCAAA CTGTACGCGT GGGAGAACAT CTTCTGCTCG 
AGGGTGGAGA TGACGCGCAG GAAGGAAATG ACCAGCCTCA GAGCCTTCGC TGTCTACACC 
TCCATCTCCA TCTTCATGAA CACAGCTATC CCCATTGCTG CCGTCCTCAT TACCTTTGTG 
GGCCACGTCA GCTTCTTCAA AGAGTCAGAC TTCTCACCCT CGGTGGCCTT TGCCTCTCTC 
TCTCTCTTCC ACATCCTGGT CACACCGCTG TTCCTGCTGT CTAGTGTGGT TCGGTCCACC 
GTCAAGGCCC TAGTGAGTGT GCAAAAGCTG AGTGAGTTCC TGTCCAGTGC AGAGATCCGT 
GAGGAACAGT GTGCCCCCCG AGAGCCTGCA CCCCAAGGCC AAGCGGGCAA GTACCAGGCG 
GTGCCCCTCA AGGTTGTGAA CCGCAAGCGC CCAGCCCGGG AAGAGGTTCG GGACCTCTTG 
GGCCCACTGC AGAGGCTGAC CCCCAGCATG GATGGAGATG CTGACAACTT CTGTGTCCAG 
ATCATCGGAG GCTTCTTCAC CTGGACCCCT GATGGAATCC CCACCCTGTC CAACATCACC 
ATCCGTATCC CCCGAGGCCA GCTGACCATG ATTGTGGGGC AGGTGGGCTG CGGCAAGTCC 
TCGCTCCTTC TGGCCACCCT GGGGGAGATG CAGAGGGTCT CCGGGGCCGT CTTCTGGAAC 
AGCAGCCTTC CAGACAGCGA GGGAGAAGAC CCCAGGTATT GCCTCAGGAC AAGCAACCCA 
GAGCGGGAGA CAGCAGCCGA CTCGGATGCC AGGAGCAGAG GCCCCGTAGC CTACGCATCT 
CAGAAACCAT GGCTGCTAAA TGCCACGGTG GAGGAGAACA TCACCTTCGA GAGTCCCTTC 
AATAAGCAAA GGTACAAGAT GGTCATCGAA GCCTGCTCCC TGCAGCCAGA CATAGACATC 
TTACCCCATG GAGACCAGAC TCAGATTGGG GAACGGGGCA TCAACTTGTC TGGTGGTCAG 
CGTCAGCGAA TCAGTGTAGC CCGAGCCCTC TACCAGCACA CCAATGTTGT CTTCTTGGAT 
GACCCTTTCT CAGCTCTGGA TGTCCATCTG AGCGACCACC TGATGCAGGC TGGCATCCTT 
GAGCTGCTCC GGGATGACAA GAGGACAGTG GTCTTGGTGA CCCACAAGCT ACAGTACCTG 
CCTCATGCAG ACTGGATCAT TGCTATGAAG GATGGCACCA TTCAGAGGGA GGGGACGCTC 
AAGGACTTCC AGAGGTCTGA GTGCCAGCTC TTTGAGCATT GGAAGACCCT CATGAACAGG 
CAAGACCAAG AGCTGGAGAA GGAGACAGTC ATGGAGAGGA AAGCCCCAGA ACCGTCTCAG 
GGCCTGCCCC GTGCCATGTC CTCAAGAGAT GGCCTTCTGC TGGATGAGGA CGAGGAGGAA 
GAGGAGGCGG CCGAGAGCGA GGAAGATGAC AACTTATCTT CGGTGCTGCA TCAGCGAGCC 
AAGATCCCAT GGCGGGCCTG CACTAAGTAT TTGTCCTCTG CCGGCGTCCT GCTCTTGTCC 
CTGCTTGTCT TCTCCCAGCT ACTCAAGCAC ATGGTCTTGG TGGCCATTGA TTACTGGCTG 
GCCAAGTGGA CGGACAGTGC CCTGGTCCTG AGCCCTGCTG CCAGGAACTG CTCCCTCAGC 
CAGGAATGCG CCCTGGACCA GTCTGTCTAT GCCATGGTAT TCACCGTGCT CTGCAGCCTG 
GGAATTGCAC TGTGCCTTGT CACCTCTGTC ACTGTGGAGT GGACAGGACT GAAGGTGGCC 
AAGAGGCTGC ACCGCAGCCT GCTCAATCGC ATCATCCTGG CCCCCATGAG GTTCTTTGAG 
ACCACGCCCC TGGGGAGTAT CCTGAACAGA TTTTCATCTG ACTGTAACAC CATTGACCAG 
CACATCCCAT CCACGCTGGA GTGTCTGAGC CGATCCACTC TACTCTGTGT CTCCGCCTTG 
ACTGTCATCT CCTACGTCAC ACCTGTGTTC CTCGTGGCCC TCTTACCCCT AGCTGTGGTG 
TGCTACTTCA TCCAGAAATA CTTCCGAGTG GCGTCCAGGG ACCTGCAGCA GCTGGATGAC 
ACAACGCAGC TCCCTCTGCT CTCACACTTT GCTGAAACCG TGGAAGGACT CACCACCATC 
CGTGCCTTCA GGTACGAGGC CCGGTTCCAG CAGAAGCTCC TGGAGTACAC GGACTCCAAC 
AACATCGCCT CCCTCTTCCT CACGGCAGCC AACAGGTGGC TAGAAGTCCG CATGGAGTAC 
ATTGGAGCAT GCGTGGTACT CATCGCAGCC GCCACCTCCA TCTCCAACTC CCTGCACAGG 
GAGCTCTCTG CTGGTCTGGT GGGCCTGGGC CTCACCTACG CCTTGATGGT CTCCAACTAC 
CTCAACTGGA TGGTGAGGAA CCTGGCAGAC ATGGAGATCC AATTGGGGGC TGTGAAGCGC 
ATCCACACAC TCCTGAAAAC TGAGGCAGAG AGCTATGAGG GGCTCCTAGC ACCGTCATTG 
ATCCCCAAGA ACTGGCCAGA CCAAGGGAAG ATTCAAATTC AAAACCTGAG TGTGCGCTAT 
GACAGCTCCC TGAAGCCCGT GCTGAAGCAC GTCAATGCCC TCATCGCCCC AGGACAGAAG 
ATCGGGATCT GCGGCCGCAC AGGCAGTGGG AAGTCCTCCT TCTCTCTCGC CTTTTTCCGA 
ATGGTGGACA TGTTCGAAGG GCGCATCATC ATTGATGGCA TCGACATCGC CAAGCTGCCG 
CTGCACACGC TCCGTTCACG CCTCTCCATC ATCCTACAGG ACCCTGTCCT CTTCAGCGGC 
ACCATCAGAT TCAACCTGGA CCCAGAGAAG AAATGCTCAG ACAGCACACT CTGGGAGGCT 
CTGGAGATCG CCCAGCTGAA GCTGGTGGTG AAGGCACTGC CAGGAGGCCT GGATGCCATC 
ATCACAGAAG GAGGGGAGAA TTTTAGTCAA GGTCAGAGGC AGCTGTTCTG CCTGGCTCGG 
GCCTTCGTGA GAAAGACCAG CATCTTCATC ATGGACGAAG CAACTGCCTC CATTGACATG 
GCTACGGAAA ACATCCTCCA GAAGGTGGTG ATGACAGCCT TCGCAGACCG CACTGTGGTC 
ACCATCGCGC ACCGCGTACA CACCATCCTG AGTGCAGACC TCGTGATGGT CCTGAAGAGG 
GGAGCCATCC TGGAGTTTGA CAAACCGGAG AAGCTTCTGA GCCAGAAGGA CAGCGTCTTC 
GCCTCCTTCG TCCGCGCGGA CAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_035640.2
CDS	85..4851
Translation	MPLAFCGTENHSAAYRVDQGVLNNGCFVDALNVVPHVFLLFITFPILFIGWGSQSSKVHIHHSTWLHFPGHNLRWILTFMLLFVLVCEIAEGILSDGVTESRHLHLYMPAGMAFMAAITSVVYYHNIETSNFPKLLIALLIYWTLAFITKTIKFVKFYDHAIGFSQLRFCLTGLLVILYGMLLLVEINVIRVRRYIFFKTPREVKPPEDLQDLGVRFLQPFVNLLSKGTYWWMNAFIKTAHRKPIDLRAIGKLPIAMRALTNYQRLCAAFDAQARKDTQSQQGARAIWRALCHAFGRRLVLSSTFRILADLLGFAGPLCIFGIVDHLGKENHVFQPKTQFLGVYFVSSQEFLGNAYVLAVLLFLALLLQRTFLQASYYVAIETGINLRGAIQTKIYNKIMHLSTSNLSMGEMTAGQICNLVAIDTNQLMWFFFLCPNLWAMPVQIIVGVILLYYILGVSALIGAAVIILLAPVQYFVATKLSQAQRSTLEYSNERLKQTNEMLRGIKLLKLYAWENIFCSRVEMTRRKEMTSLRAFAVYTSISIFMNTAIPIAAVLITFVGHVSFFKESDFSPSVAFASLSLFHILVTPLFLLSSVVRSTVKALVSVQKLSEFLSSAEIREEQCAPREPAPQGQAGKYQAVPLKVVNRKRPAREEVRDLLGPLQRLTPSMDGDADNFCVQIIGGFFTWTPDGIPTLSNITIRIPRGQLTMIVGQVGCGKSSLLLATLGEMQRVSGAVFWNSSLPDSEGEDPRYCLRTSNPERETAADSDARSRGPVAYASQKPWLLNATVEENITFESPFNKQRYKMVIEACSLQPDIDILPHGDQTQIGERGINLSGGQRQRISVARALYQHTNVVFLDDPFSALDVHLSDHLMQAGILELLRDDKRTVVLVTHKLQYLPHADWIIAMKDGTIQREGTLKDFQRSECQLFEHWKTLMNRQDQELEKETVMERKAPEPSQGLPRAMSSRDGLLLDEDEEEEEAAESEEDDNLSSVLHQRAKIPWRACTKYLSSAGVLLLSLLVFSQLLKHMVLVAIDYWLAKWTDSALVLSPAARNCSLSQECALDQSVYAMVFTVLCSLGIALCLVTSVTVEWTGLKVAKRLHRSLLNRIILAPMRFFETTPLGSILNRFSSDCNTIDQHIPSTLECLSRSTLLCVSALTVISYVTPVFLVALLPLAVVCYFIQKYFRVASRDLQQLDDTTQLPLLSHFAETVEGLTTIRAFRYEARFQQKLLEYTDSNNIASLFLTAANRWLEVRMEYIGACVVLIAAATSISNSLHRELSAGLVGLGLTYALMVSNYLNWMVRNLADMEIQLGAVKRIHTLLKTEAESYEGLLAPSLIPKNWPDQGKIQIQNLSVRYDSSLKPVLKHVNALIAPGQKIGICGRTGSGKSSFSLAFFRMVDMFEGRIIIDGIDIAKLPLHTLRSRLSIILQDPVLFSGTIRFNLDPEKKCSDSTLWEALEIAQLKLVVKALPGGLDAIITEGGENFSQGQRQLFCLARAFVRKTSIFIMDEATASIDMATENILQKVVMTAFADRTVVTIAHRVHTILSADLVMVLKRGAILEFDKPEKLLSQKDSVFASFVRADK

Target ORF information:

RefSeq Version	NM_011510.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus ATP-binding cassette, sub-family C (CFTR/MRP), member 8 (Abcc8), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_011510.3

ORF Insert Sequence:

ATGCCCTTGG CCTTCTGCGG CACCGAGAAC CACTCGGCCG CCTACCGGGT GGACCAAGGT 
GTCCTCAACA ACGGCTGCTT CGTGGACGCG CTCAACGTAG TGCCACATGT CTTCCTGCTC 
TTCATCACAT TCCCCATCCT CTTCATCGGA TGGGGCAGCC AGAGCTCCAA GGTACACATT 
CACCATAGCA CCTGGCTCCA TTTCCCTGGC CACAACCTGC GCTGGATCCT TACCTTCATG 
CTGCTCTTTG TCCTGGTGTG TGAGATCGCT GAGGGTATCC TGTCTGATGG GGTGACAGAA 
TCCCGCCACC TCCATTTGTA CATGCCAGCT GGGATGGCTT TCATGGCTGC CATCACCTCT 
GTGGTCTACT ATCACAACAT TGAGACCTCT AACTTCCCCA AGCTGCTGAT CGCTCTGCTT 
ATCTACTGGA CCTTGGCCTT CATCACTAAG ACCATCAAGT TCGTCAAGTT CTACGACCAC 
GCCATCGGCT TCTCTCAGCT GCGCTTCTGC CTCACGGGGC TTCTGGTGAT CCTCTACGGG 
ATGCTGCTGC TGGTGGAGAT CAATGTCATC CGGGTGCGGA GGTACATCTT CTTCAAGACG 
CCAAGGGAAG TGAAGCCCCC TGAGGACCTG CAGGACCTGG GGGTGCGCTT TCTGCAGCCC 
TTCGTGAATC TGCTGTCAAA GGGGACCTAC TGGTGGATGA ATGCCTTCAT CAAGACTGCC 
CACAGGAAGC CCATCGACCT GCGGGCCATC GGGAAGCTGC CCATCGCCAT GAGAGCCCTC 
ACCAACTATC AGCGACTCTG CGCGGCCTTC GATGCCCAGG CGCGGAAAGA CACGCAGAGC 
CAGCAGGGCG CCCGGGCCAT CTGGAGGGCT CTCTGCCATG CCTTTGGGAG ACGCCTGGTC 
CTCAGCAGCA CATTCCGTAT CCTGGCTGAC CTGCTGGGCT TTGCTGGACC GCTCTGCATC 
TTTGGGATCG TGGACCACCT CGGGAAGGAG AACCATGTCT TCCAGCCCAA GACACAGTTT 
CTTGGGGTTT ACTTTGTCTC GTCCCAAGAG TTCCTGGGCA ACGCCTATGT CTTGGCTGTA 
CTTCTGTTCC TGGCCCTCCT GCTGCAAAGG ACGTTCCTGC AAGCCTCGTA CTACGTCGCC 
ATTGAAACTG GGATTAACCT GAGAGGGGCG ATCCAGACCA AGATTTACAA TAAGATCATG 
CACTTGTCTA CTTCCAACCT GTCAATGGGG GAGATGACGG CTGGGCAGAT CTGCAACCTG 
GTGGCCATCG ACACAAATCA GCTCATGTGG TTTTTCTTCT TATGCCCAAA CCTCTGGGCT 
ATGCCAGTAC AGATCATTGT GGGCGTGATC CTCCTCTACT ACATCCTTGG GGTCAGTGCC 
TTGATTGGAG CAGCTGTCAT CATTCTGCTG GCTCCTGTAC AGTACTTTGT GGCCACCAAG 
CTCTCCCAGG CACAGCGGAG CACCCTGGAA TATTCCAATG AAAGGCTGAA GCAGACCAAC 
GAGATGCTCC GGGGCATCAA ACTGCTCAAA CTGTACGCGT GGGAGAACAT CTTCTGCTCG 
AGGGTGGAGA TGACGCGCAG GAAGGAAATG ACCAGCCTCA GAGCCTTCGC TGTCTACACC 
TCCATCTCCA TCTTCATGAA CACAGCTATC CCCATTGCTG CCGTCCTCAT TACCTTTGTG 
GGCCACGTCA GCTTCTTCAA AGAGTCAGAC TTCTCACCCT CGGTGGCCTT TGCCTCTCTC 
TCTCTCTTCC ACATCCTGGT CACACCGCTG TTCCTGCTGT CTAGTGTGGT TCGGTCCACC 
GTCAAGGCCC TAGTGAGTGT GCAAAAGCTG AGTGAGTTCC TGTCCAGTGC AGAGATCCGT 
GAGGAACAGT GTGCCCCCCG AGAGCCTGCA CCCCAAGGCC AAGCGGGCAA GTACCAGGCG 
GTGCCCCTCA AGGTTGTGAA CCGCAAGCGC CCAGCCCGGG AAGAGGTTCG GGACCTCTTG 
GGCCCACTGC AGAGGCTGAC CCCCAGCATG GATGGAGATG CTGACAACTT CTGTGTCCAG 
ATCATCGGAG GCTTCTTCAC CTGGACCCCT GATGGAATCC CCACCCTGTC CAACATCACC 
ATCCGTATCC CCCGAGGCCA GCTGACCATG ATTGTGGGGC AGGTGGGCTG CGGCAAGTCC 
TCGCTCCTTC TGGCCACCCT GGGGGAGATG CAGAGGGTCT CCGGGGCCGT CTTCTGGAAC 
AGCAGCCTTC CAGACAGCGA GGGAGAAGAC CCCAGGTATT GCCTCAGGAC AAGCAACCCA 
GAGCGGGAGA CAGCAGCCGA CTCGGATGCC AGGAGCAGAG GCCCCGTAGC CTACGCATCT 
CAGAAACCAT GGCTGCTAAA TGCCACGGTG GAGGAGAACA TCACCTTCGA GAGTCCCTTC 
AATAAGCAAA GGTACAAGAT GGTCATCGAA GCCTGCTCCC TGCAGCCAGA CATAGACATC 
TTACCCCATG GAGACCAGAC TCAGATTGGG GAACGGGGCA TCAACTTGTC TGGTGGTCAG 
CGTCAGCGAA TCAGTGTAGC CCGAGCCCTC TACCAGCACA CCAATGTTGT CTTCTTGGAT 
GACCCTTTCT CAGCTCTGGA TGTCCATCTG AGCGACCACC TGATGCAGGC TGGCATCCTT 
GAGCTGCTCC GGGATGACAA GAGGACAGTG GTCTTGGTGA CCCACAAGCT ACAGTACCTG 
CCTCATGCAG ACTGGATCAT TGCTATGAAG GATGGCACCA TTCAGAGGGA GGGGACGCTC 
AAGGACTTCC AGAGGTCTGA GTGCCAGCTC TTTGAGCATT GGAAGACCCT CATGAACAGG 
CAAGACCAAG AGCTGGAGAA GGAGACAGTC ATGGAGAGGA AAGCCCCAGA ACCGTCTCAG 
GGCCTGCCCC GTGCCATGTC CTCAAGAGAT GGCCTTCTGC TGGATGAGGA CGAGGAGGAA 
GAGGAGGCGG CCGAGAGCGA GGAAGATGAC AACTTATCTT CGGTGCTGCA TCAGCGAGCC 
AAGATCCCAT GGCGGGCCTG CACTAAGTAT TTGTCCTCTG CCGGCGTCCT GCTCTTGTCC 
CTGCTTGTCT TCTCCCAGCT ACTCAAGCAC ATGGTCTTGG TGGCCATTGA TTACTGGCTG 
GCCAAGTGGA CGGACAGTGC CCTGGTCCTG AGCCCTGCTG CCAGGAACTG CTCCCTCAGC 
CAGGAATGCG CCCTGGACCA GTCTGTCTAT GCCATGGTAT TCACCGTGCT CTGCAGCCTG 
GGAATTGCAC TGTGCCTTGT CACCTCTGTC ACTGTGGAGT GGACAGGACT GAAGGTGGCC 
AAGAGGCTGC ACCGCAGCCT GCTCAATCGC ATCATCCTGG CCCCCATGAG GTTCTTTGAG 
ACCACGCCCC TGGGGAGTAT CCTGAACAGA TTTTCATCTG ACTGTAACAC CATTGACCAG 
CACATCCCAT CCACGCTGGA GTGTCTGAGC CGATCCACTC TACTCTGTGT CTCCGCCTTG 
ACTGTCATCT CCTACGTCAC ACCTGTGTTC CTCGTGGCCC TCTTACCCCT AGCTGTGGTG 
TGCTACTTCA TCCAGAAATA CTTCCGAGTG GCGTCCAGGG ACCTGCAGCA GCTGGATGAC 
ACAACGCAGC TCCCTCTGCT CTCACACTTT GCTGAAACCG TGGAAGGACT CACCACCATC 
CGTGCCTTCA GGTACGAGGC CCGGTTCCAG CAGAAGCTCC TGGAGTACAC GGACTCCAAC 
AACATCGCCT CCCTCTTCCT CACGGCAGCC AACAGGTGGC TAGAAGTCCG CATGGAGTAC 
ATTGGAGCAT GCGTGGTACT CATCGCAGCC GCCACCTCCA TCTCCAACTC CCTGCACAGG 
GAGCTCTCTG CTGGTCTGGT GGGCCTGGGC CTCACCTACG CCTTGATGGT CTCCAACTAC 
CTCAACTGGA TGGTGAGGAA CCTGGCAGAC ATGGAGATCC AATTGGGGGC TGTGAAGCGC 
ATCCACACAC TCCTGAAAAC TGAGGCAGAG AGCTATGAGG GGCTCCTAGC ACCGTCATTG 
ATCCCCAAGA ACTGGCCAGA CCAAGGGAAG ATTCAAATTC AAAACCTGAG TGTGCGCTAT 
GACAGCTCCC TGAAGCCCGT GCTGAAGCAC GTCAATGCCC TCATCGCCCC AGGACAGAAG 
ATCGGGATCT GCGGCCGCAC AGGCAGTGGG AAGTCCTCCT TCTCTCTCGC CTTTTTCCGA 
ATGGTGGACA TGTTCGAAGG GCGCATCATC ATTGATGGCA TCGACATCGC CAAGCTGCCG 
CTGCACACGC TCCGTTCACG CCTCTCCATC ATCCTACAGG ACCCTGTCCT CTTCAGCGGC 
ACCATCAGAT TCAACCTGGA CCCAGAGAAG AAATGCTCAG ACAGCACACT CTGGGAGGCT 
CTGGAGATCG CCCAGCTGAA GCTGGTGGTG AAGGCACTGC CAGGAGGCCT GGATGCCATC 
ATCACAGAAG GAGGGGAGAA TTTTAGTCAA GGTCAGAGGC AGCTGTTCTG CCTGGCTCGG 
GCCTTCGTGA GAAAGACCAG CATCTTCATC ATGGACGAAG CAACTGCCTC CATTGACATG 
GCTACGGAAA ACATCCTCCA GAAGGTGGTG ATGACAGCCT TCGCAGACCG CACTGTGGTC 
ACCATCGCGC ACCGCGTACA CACCATCCTG AGTGCAGACC TCGTGATGGT CCTGAAGAGG 
GGAGCCATCC TGGAGTTTGA CAAACCGGAG AAGCTTCTGA GCCAGAAGGA CAGCGTCTTC 
GCCTCCTTCG TCCGCGCGGA CAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ABCC8 ( NM_001357538.1 ) cDNA ORF clone, Mus musculus(House mouse) -> NP_001344467.1 Mus musculus ATP-binding cassette, sub-family C (CFTR/MRP), member 8 (Abcc8), transcript variant 2, mRNA.

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CloneID	OMu38750
Clone ID Related Accession (Same CDS sequence)	NM_001357538.1 , XM_006540750.1
Accession Version	NM_001357538.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4746bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-22
Organism	Mus musculus(house mouse)
Product	ATP-binding cassette sub-family C member 8 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC120135.7 and AC115036.10. On Nov 4, 2017 this sequence version replaced XM_006540750.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660813.95336.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCCTTGG CCTTCTGCGG CACCGAGAAC CACTCGGCCG CCTACCGGGT GGACCAAGGT 
GTCCTCAACA ACGGCTGCTT CGTGGACGCG CTCAACGTAG TGCCACATGT CTTCCTGCTC 
TTCATCACAT TCCCCATCCT CTTCATCGGA TGGGGCAGCC AGAGCTCCAA GGTACACATT 
CACCATAGCA CCTGGCTCCA TTTCCCTGGC CACAACCTGC GCTGGATCCT TACCTTCATG 
CTGCTCTTTG TCCTGGTGTG TGAGATCGCT GAGGGTATCC TGTCTGATGG GGTGACAGAA 
TCCCGCCACC TCCATTTGTA CATGCCAGCT GGGATGGCTT TCATGGCTGC CATCACCTCT 
GTGGTCTACT ATCACAACAT TGAGACCTCT AACTTCCCCA AGCTGCTGAT CGCTCTGCTT 
ATCTACTGGA CCTTGGCCTT CATCACTAAG ACCATCAAGT TCGTCAAGTT CTACGACCAC 
GCCATCGGCT TCTCTCAGCT GCGCTTCTGC CTCACGGGGC TTCTGGTGAT CCTCTACGGG 
ATGCTGCTGC TGGTGGAGAT CAATGTCATC CGGGTGCGGA GGTACATCTT CTTCAAGACG 
CCAAGGGAAG TGAAGCCCCC TGAGGACCTG CAGGACCTGG GGGTGCGCTT TCTGCAGCCC 
TTCGTGAATC TGCTGTCAAA GGGGACCTAC TGGTGGATGA ATGCCTTCAT CAAGACTGCC 
CACAGGAAGC CCATCGACCT GCGGGCCATC GGGAAGCTGC CCATCGCCAT GAGAGCCCTC 
ACCAACTATC AGCGACTCTG CGCGGCCTTC GATGCCCAGG CGCGGAAAGA CACGCAGAGC 
CAGCAGGGCG CCCGGGCCAT CTGGAGGGCT CTCTGCCATG CCTTTGGGAG ACGCCTGGTC 
CTCAGCAGCA CATTCCGTAT CCTGGCTGAC CTGCTGGGCT TTGCTGGACC GCTCTGCATC 
TTTGGGATCG TGGACCACCT CGGGAAGGAG AACCATGTCT TCCAGCCCAA GACACAGTTT 
CTTGGGGTTT ACTTTGTCTC GTCCCAAGAG TTCCTGGGCA ACGCCTATGT CTTGGCTGTA 
CTTCTGTTCC TGGCCCTCCT GCTGCAAAGG ACGTTCCTGC AAGCCTCGTA CTACGTCGCC 
ATTGAAACTG GGATTAACCT GAGAGGGGCG ATCCAGACCA AGATTTACAA TAAGATCATG 
CACTTGTCTA CTTCCAACCT GTCAATGGGG GAGATGACGG CTGGGCAGAT CTGCAACCTG 
GTGGCCATCG ACACAAATCA GCTCATGTGG TTTTTCTTCT TATGCCCAAA CCTCTGGGCT 
ATGCCAGTAC AGATCATTGT GGGCGTGATC CTCCTCTACT ACATCCTTGG GGTCAGTGCC 
TTGATTGGAG CAGCTGTCAT CATTCTGCTG GCTCCTGTAC AGTACTTTGT GGCCACCAAG 
CTCTCCCAGG CACAGCGGAG CACCCTGGAA TATTCCAATG AAAGGCTGAA GCAGACCAAC 
GAGATGCTCC GGGGCATCAA ACTGCTCAAA CTGTACGCGT GGGAGAACAT CTTCTGCTCG 
AGGGTGGAGA TGACGCGCAG GAAGGAAATG ACCAGCCTCA GAGCCTTCGC TGTCTACACC 
TCCATCTCCA TCTTCATGAA CACAGCTATC CCCATTGCTG CCGTCCTCAT TACCTTTGTG 
GGCCACGTCA GCTTCTTCAA AGAGTCAGAC TTCTCACCCT CGGTGGCCTT TGCCTCTCTC 
TCTCTCTTCC ACATCCTGGT CACACCGCTG TTCCTGCTGT CTAGTGTGGT TCGGTCCACC 
GTCAAGGCCC TAGTGAGTGT GCAAAAGCTG AGTGAGTTCC TGTCCAGTGC AGAGATCCGT 
GAGGAACAGT GTGCCCCCCG AGAGCCTGCA CCCCAAGGCC AAGCGGGCAA GTACCAGGCG 
GTGCCCCTCA AGGTTGTGAA CCGCAAGCGC CCAGCCCGGG AAGAGGTTCG GGACCTCTTG 
GGCCCACTGC AGAGGCTGAC CCCCAGCATG GATGGAGATG CTGACAACTT CTGTGTCCAG 
ATCATCGGAG GCTTCTTCAC CTGGACCCCT GATGGAATCC CCACCCTGTC CAACATCACC 
ATCCGTATCC CCCGAGGCCA GCTGACCATG ATTGTGGGGC AGGTGGGCTG CGGCAAGTCC 
TCGCTCCTTC TGGCCACCCT GGGGGAGATG CAGAGGGTCT CCGGGGCCGT CTTCTGGAAC 
AGCCTTCCAG ACAGCGAGGG AGAAGACCCC AGCAACCCAG AGCGGGAGAC AGCAGCCGAC 
TCGGATGCCA GGAGCAGAGG CCCCGTAGCC TACGCATCTC AGAAACCATG GCTGCTAAAT 
GCCACGGTGG AGGAGAACAT CACCTTCGAG AGTCCCTTCA ATAAGCAAAG GTACAAGATG 
GTCATCGAAG CCTGCTCCCT GCAGCCAGAC ATAGACATCT TACCCCATGG AGACCAGACT 
CAGATTGGGG AACGGGGCAT CAACTTGTCT GGTGGTCAGC GTCAGCGAAT CAGTGTAGCC 
CGAGCCCTCT ACCAGCACAC CAATGTTGTC TTCTTGGATG ACCCTTTCTC AGCTCTGGAT 
GTCCATCTGA GCGACCACCT GATGCAGGCT GGCATCCTTG AGCTGCTCCG GGATGACAAG 
AGGACAGTGG TCTTGGTGAC CCACAAGCTA CAGTACCTGC CTCATGCAGA CTGGATCATT 
GCTATGAAGG ATGGCACCAT TCAGAGGGAG GGGACGCTCA AGGACTTCCA GAGGTCTGAG 
TGCCAGCTCT TTGAGCATTG GAAGACCCTC ATGAACAGGC AAGACCAAGA GCTGGAGAAG 
GAGACAGTCA TGGAGAGGAA AGCCCCAGAA CCGTCTCAGG GCCTGCCCCG TGCCATGTCC 
TCAAGAGATG GCCTTCTGCT GGATGAGGAC GAGGAGGAAG AGGAGGCGGC CGAGAGCGAG 
GAAGATGACA ACTTATCTTC GGTGCTGCAT CAGCGAGCCA AGATCCCATG GCGGGCCTGC 
ACTAAGTATT TGTCCTCTGC CGGCGTCCTG CTCTTGTCCC TGCTTGTCTT CTCCCAGCTA 
CTCAAGCACA TGGTCTTGGT GGCCATTGAT TACTGGCTGG CCAAGTGGAC GGACAGTGCC 
CTGGTCCTGA GCCCTGCTGC CAGGAACTGC TCCCTCAGCC AGGAATGCGC CCTGGACCAG 
TCTGTCTATG CCATGGTATT CACCGTGCTC TGCAGCCTGG GAATTGCACT GTGCCTTGTC 
ACCTCTGTCA CTGTGGAGTG GACAGGACTG AAGGTGGCCA AGAGGCTGCA CCGCAGCCTG 
CTCAATCGCA TCATCCTGGC CCCCATGAGG TTCTTTGAGA CCACGCCCCT GGGGAGTATC 
CTGAACAGAT TTTCATCTGA CTGTAACACC ATTGACCAGC ACATCCCATC CACGCTGGAG 
TGTCTGAGCC GATCCACTCT ACTCTGTGTC TCCGCCTTGA CTGTCATCTC CTACGTCACA 
CCTGTGTTCC TCGTGGCCCT CTTACCCCTA GCTGTGGTGT GCTACTTCAT CCAGAAATAC 
TTCCGAGTGG CGTCCAGGGA CCTGCAGCAG CTGGATGACA CAACGCAGCT CCCTCTGCTC 
TCACACTTTG CTGAAACCGT GGAAGGACTC ACCACCATCC GTGCCTTCAG GTACGAGGCC 
CGGTTCCAGC AGAAGCTCCT GGAGTACACG GACTCCAACA ACATCGCCTC CCTCTTCCTC 
ACGGCAGCCA ACAGGTGGCT AGAAGTCCGC ATGGAGTACA TTGGAGCATG CGTGGTACTC 
ATCGCAGCCG CCACCTCCAT CTCCAACTCC CTGCACAGGG AGCTCTCTGC TGGTCTGGTG 
GGCCTGGGCC TCACCTACGC CTTGATGGTC TCCAACTACC TCAACTGGAT GGTGAGGAAC 
CTGGCAGACA TGGAGATCCA ATTGGGGGCT GTGAAGCGCA TCCACACACT CCTGAAAACT 
GAGGCAGAGA GCTATGAGGG GCTCCTAGCA CCGTCATTGA TCCCCAAGAA CTGGCCAGAC 
CAAGGGAAGA TTCAAATTCA AAACCTGAGT GTGCGCTATG ACAGCTCCCT GAAGCCCGTG 
CTGAAGCACG TCAATGCCCT CATCGCCCCA GGACAGAAGA TCGGGATCTG CGGCCGCACA 
GGCAGTGGGA AGTCCTCCTT CTCTCTCGCC TTTTTCCGAA TGGTGGACAT GTTCGAAGGG 
CGCATCATCA TTGATGGCAT CGACATCGCC AAGCTGCCGC TGCACACGCT CCGTTCACGC 
CTCTCCATCA TCCTACAGGA CCCTGTCCTC TTCAGCGGCA CCATCAGATT CAACCTGGAC 
CCAGAGAAGA AATGCTCAGA CAGCACACTC TGGGAGGCTC TGGAGATCGC CCAGCTGAAG 
CTGGTGGTGA AGGCACTGCC AGGAGGCCTG GATGCCATCA TCACAGAAGG AGGGGAGAAT 
TTTAGTCAAG GTCAGAGGCA GCTGTTCTGC CTGGCTCGGG CCTTCGTGAG AAAGACCAGC 
ATCTTCATCA TGGACGAAGC AACTGCCTCC ATTGACATGG CTACGGAAAA CATCCTCCAG 
AAGGTGGTGA TGACAGCCTT CGCAGACCGC ACTGTGGTCA CCATCGCGCA CCGCGTACAC 
ACCATCCTGA GTGCAGACCT CGTGATGGTC CTGAAGAGGG GAGCCATCCT GGAGTTTGAC 
AAACCGGAGA AGCTTCTGAG CCAGAAGGAC AGCGTCTTCG CCTCCTTCGT CCGCGCGGAC 
AAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001344467.1
CDS	85..4830
Translation	MPLAFCGTENHSAAYRVDQGVLNNGCFVDALNVVPHVFLLFITFPILFIGWGSQSSKVHIHHSTWLHFPGHNLRWILTFMLLFVLVCEIAEGILSDGVTESRHLHLYMPAGMAFMAAITSVVYYHNIETSNFPKLLIALLIYWTLAFITKTIKFVKFYDHAIGFSQLRFCLTGLLVILYGMLLLVEINVIRVRRYIFFKTPREVKPPEDLQDLGVRFLQPFVNLLSKGTYWWMNAFIKTAHRKPIDLRAIGKLPIAMRALTNYQRLCAAFDAQARKDTQSQQGARAIWRALCHAFGRRLVLSSTFRILADLLGFAGPLCIFGIVDHLGKENHVFQPKTQFLGVYFVSSQEFLGNAYVLAVLLFLALLLQRTFLQASYYVAIETGINLRGAIQTKIYNKIMHLSTSNLSMGEMTAGQICNLVAIDTNQLMWFFFLCPNLWAMPVQIIVGVILLYYILGVSALIGAAVIILLAPVQYFVATKLSQAQRSTLEYSNERLKQTNEMLRGIKLLKLYAWENIFCSRVEMTRRKEMTSLRAFAVYTSISIFMNTAIPIAAVLITFVGHVSFFKESDFSPSVAFASLSLFHILVTPLFLLSSVVRSTVKALVSVQKLSEFLSSAEIREEQCAPREPAPQGQAGKYQAVPLKVVNRKRPAREEVRDLLGPLQRLTPSMDGDADNFCVQIIGGFFTWTPDGIPTLSNITIRIPRGQLTMIVGQVGCGKSSLLLATLGEMQRVSGAVFWNSLPDSEGEDPSNPERETAADSDARSRGPVAYASQKPWLLNATVEENITFESPFNKQRYKMVIEACSLQPDIDILPHGDQTQIGERGINLSGGQRQRISVARALYQHTNVVFLDDPFSALDVHLSDHLMQAGILELLRDDKRTVVLVTHKLQYLPHADWIIAMKDGTIQREGTLKDFQRSECQLFEHWKTLMNRQDQELEKETVMERKAPEPSQGLPRAMSSRDGLLLDEDEEEEEAAESEEDDNLSSVLHQRAKIPWRACTKYLSSAGVLLLSLLVFSQLLKHMVLVAIDYWLAKWTDSALVLSPAARNCSLSQECALDQSVYAMVFTVLCSLGIALCLVTSVTVEWTGLKVAKRLHRSLLNRIILAPMRFFETTPLGSILNRFSSDCNTIDQHIPSTLECLSRSTLLCVSALTVISYVTPVFLVALLPLAVVCYFIQKYFRVASRDLQQLDDTTQLPLLSHFAETVEGLTTIRAFRYEARFQQKLLEYTDSNNIASLFLTAANRWLEVRMEYIGACVVLIAAATSISNSLHRELSAGLVGLGLTYALMVSNYLNWMVRNLADMEIQLGAVKRIHTLLKTEAESYEGLLAPSLIPKNWPDQGKIQIQNLSVRYDSSLKPVLKHVNALIAPGQKIGICGRTGSGKSSFSLAFFRMVDMFEGRIIIDGIDIAKLPLHTLRSRLSIILQDPVLFSGTIRFNLDPEKKCSDSTLWEALEIAQLKLVVKALPGGLDAIITEGGENFSQGQRQLFCLARAFVRKTSIFIMDEATASIDMATENILQKVVMTAFADRTVVTIAHRVHTILSADLVMVLKRGAILEFDKPEKLLSQKDSVFASFVRADK

Target ORF information:

RefSeq Version	NM_001357538.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus ATP-binding cassette, sub-family C (CFTR/MRP), member 8 (Abcc8), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001357538.1

ORF Insert Sequence:

ATGCCCTTGG CCTTCTGCGG CACCGAGAAC CACTCGGCCG CCTACCGGGT GGACCAAGGT 
GTCCTCAACA ACGGCTGCTT CGTGGACGCG CTCAACGTAG TGCCACATGT CTTCCTGCTC 
TTCATCACAT TCCCCATCCT CTTCATCGGA TGGGGCAGCC AGAGCTCCAA GGTACACATT 
CACCATAGCA CCTGGCTCCA TTTCCCTGGC CACAACCTGC GCTGGATCCT TACCTTCATG 
CTGCTCTTTG TCCTGGTGTG TGAGATCGCT GAGGGTATCC TGTCTGATGG GGTGACAGAA 
TCCCGCCACC TCCATTTGTA CATGCCAGCT GGGATGGCTT TCATGGCTGC CATCACCTCT 
GTGGTCTACT ATCACAACAT TGAGACCTCT AACTTCCCCA AGCTGCTGAT CGCTCTGCTT 
ATCTACTGGA CCTTGGCCTT CATCACTAAG ACCATCAAGT TCGTCAAGTT CTACGACCAC 
GCCATCGGCT TCTCTCAGCT GCGCTTCTGC CTCACGGGGC TTCTGGTGAT CCTCTACGGG 
ATGCTGCTGC TGGTGGAGAT CAATGTCATC CGGGTGCGGA GGTACATCTT CTTCAAGACG 
CCAAGGGAAG TGAAGCCCCC TGAGGACCTG CAGGACCTGG GGGTGCGCTT TCTGCAGCCC 
TTCGTGAATC TGCTGTCAAA GGGGACCTAC TGGTGGATGA ATGCCTTCAT CAAGACTGCC 
CACAGGAAGC CCATCGACCT GCGGGCCATC GGGAAGCTGC CCATCGCCAT GAGAGCCCTC 
ACCAACTATC AGCGACTCTG CGCGGCCTTC GATGCCCAGG CGCGGAAAGA CACGCAGAGC 
CAGCAGGGCG CCCGGGCCAT CTGGAGGGCT CTCTGCCATG CCTTTGGGAG ACGCCTGGTC 
CTCAGCAGCA CATTCCGTAT CCTGGCTGAC CTGCTGGGCT TTGCTGGACC GCTCTGCATC 
TTTGGGATCG TGGACCACCT CGGGAAGGAG AACCATGTCT TCCAGCCCAA GACACAGTTT 
CTTGGGGTTT ACTTTGTCTC GTCCCAAGAG TTCCTGGGCA ACGCCTATGT CTTGGCTGTA 
CTTCTGTTCC TGGCCCTCCT GCTGCAAAGG ACGTTCCTGC AAGCCTCGTA CTACGTCGCC 
ATTGAAACTG GGATTAACCT GAGAGGGGCG ATCCAGACCA AGATTTACAA TAAGATCATG 
CACTTGTCTA CTTCCAACCT GTCAATGGGG GAGATGACGG CTGGGCAGAT CTGCAACCTG 
GTGGCCATCG ACACAAATCA GCTCATGTGG TTTTTCTTCT TATGCCCAAA CCTCTGGGCT 
ATGCCAGTAC AGATCATTGT GGGCGTGATC CTCCTCTACT ACATCCTTGG GGTCAGTGCC 
TTGATTGGAG CAGCTGTCAT CATTCTGCTG GCTCCTGTAC AGTACTTTGT GGCCACCAAG 
CTCTCCCAGG CACAGCGGAG CACCCTGGAA TATTCCAATG AAAGGCTGAA GCAGACCAAC 
GAGATGCTCC GGGGCATCAA ACTGCTCAAA CTGTACGCGT GGGAGAACAT CTTCTGCTCG 
AGGGTGGAGA TGACGCGCAG GAAGGAAATG ACCAGCCTCA GAGCCTTCGC TGTCTACACC 
TCCATCTCCA TCTTCATGAA CACAGCTATC CCCATTGCTG CCGTCCTCAT TACCTTTGTG 
GGCCACGTCA GCTTCTTCAA AGAGTCAGAC TTCTCACCCT CGGTGGCCTT TGCCTCTCTC 
TCTCTCTTCC ACATCCTGGT CACACCGCTG TTCCTGCTGT CTAGTGTGGT TCGGTCCACC 
GTCAAGGCCC TAGTGAGTGT GCAAAAGCTG AGTGAGTTCC TGTCCAGTGC AGAGATCCGT 
GAGGAACAGT GTGCCCCCCG AGAGCCTGCA CCCCAAGGCC AAGCGGGCAA GTACCAGGCG 
GTGCCCCTCA AGGTTGTGAA CCGCAAGCGC CCAGCCCGGG AAGAGGTTCG GGACCTCTTG 
GGCCCACTGC AGAGGCTGAC CCCCAGCATG GATGGAGATG CTGACAACTT CTGTGTCCAG 
ATCATCGGAG GCTTCTTCAC CTGGACCCCT GATGGAATCC CCACCCTGTC CAACATCACC 
ATCCGTATCC CCCGAGGCCA GCTGACCATG ATTGTGGGGC AGGTGGGCTG CGGCAAGTCC 
TCGCTCCTTC TGGCCACCCT GGGGGAGATG CAGAGGGTCT CCGGGGCCGT CTTCTGGAAC 
AGCCTTCCAG ACAGCGAGGG AGAAGACCCC AGCAACCCAG AGCGGGAGAC AGCAGCCGAC 
TCGGATGCCA GGAGCAGAGG CCCCGTAGCC TACGCATCTC AGAAACCATG GCTGCTAAAT 
GCCACGGTGG AGGAGAACAT CACCTTCGAG AGTCCCTTCA ATAAGCAAAG GTACAAGATG 
GTCATCGAAG CCTGCTCCCT GCAGCCAGAC ATAGACATCT TACCCCATGG AGACCAGACT 
CAGATTGGGG AACGGGGCAT CAACTTGTCT GGTGGTCAGC GTCAGCGAAT CAGTGTAGCC 
CGAGCCCTCT ACCAGCACAC CAATGTTGTC TTCTTGGATG ACCCTTTCTC AGCTCTGGAT 
GTCCATCTGA GCGACCACCT GATGCAGGCT GGCATCCTTG AGCTGCTCCG GGATGACAAG 
AGGACAGTGG TCTTGGTGAC CCACAAGCTA CAGTACCTGC CTCATGCAGA CTGGATCATT 
GCTATGAAGG ATGGCACCAT TCAGAGGGAG GGGACGCTCA AGGACTTCCA GAGGTCTGAG 
TGCCAGCTCT TTGAGCATTG GAAGACCCTC ATGAACAGGC AAGACCAAGA GCTGGAGAAG 
GAGACAGTCA TGGAGAGGAA AGCCCCAGAA CCGTCTCAGG GCCTGCCCCG TGCCATGTCC 
TCAAGAGATG GCCTTCTGCT GGATGAGGAC GAGGAGGAAG AGGAGGCGGC CGAGAGCGAG 
GAAGATGACA ACTTATCTTC GGTGCTGCAT CAGCGAGCCA AGATCCCATG GCGGGCCTGC 
ACTAAGTATT TGTCCTCTGC CGGCGTCCTG CTCTTGTCCC TGCTTGTCTT CTCCCAGCTA 
CTCAAGCACA TGGTCTTGGT GGCCATTGAT TACTGGCTGG CCAAGTGGAC GGACAGTGCC 
CTGGTCCTGA GCCCTGCTGC CAGGAACTGC TCCCTCAGCC AGGAATGCGC CCTGGACCAG 
TCTGTCTATG CCATGGTATT CACCGTGCTC TGCAGCCTGG GAATTGCACT GTGCCTTGTC 
ACCTCTGTCA CTGTGGAGTG GACAGGACTG AAGGTGGCCA AGAGGCTGCA CCGCAGCCTG 
CTCAATCGCA TCATCCTGGC CCCCATGAGG TTCTTTGAGA CCACGCCCCT GGGGAGTATC 
CTGAACAGAT TTTCATCTGA CTGTAACACC ATTGACCAGC ACATCCCATC CACGCTGGAG 
TGTCTGAGCC GATCCACTCT ACTCTGTGTC TCCGCCTTGA CTGTCATCTC CTACGTCACA 
CCTGTGTTCC TCGTGGCCCT CTTACCCCTA GCTGTGGTGT GCTACTTCAT CCAGAAATAC 
TTCCGAGTGG CGTCCAGGGA CCTGCAGCAG CTGGATGACA CAACGCAGCT CCCTCTGCTC 
TCACACTTTG CTGAAACCGT GGAAGGACTC ACCACCATCC GTGCCTTCAG GTACGAGGCC 
CGGTTCCAGC AGAAGCTCCT GGAGTACACG GACTCCAACA ACATCGCCTC CCTCTTCCTC 
ACGGCAGCCA ACAGGTGGCT AGAAGTCCGC ATGGAGTACA TTGGAGCATG CGTGGTACTC 
ATCGCAGCCG CCACCTCCAT CTCCAACTCC CTGCACAGGG AGCTCTCTGC TGGTCTGGTG 
GGCCTGGGCC TCACCTACGC CTTGATGGTC TCCAACTACC TCAACTGGAT GGTGAGGAAC 
CTGGCAGACA TGGAGATCCA ATTGGGGGCT GTGAAGCGCA TCCACACACT CCTGAAAACT 
GAGGCAGAGA GCTATGAGGG GCTCCTAGCA CCGTCATTGA TCCCCAAGAA CTGGCCAGAC 
CAAGGGAAGA TTCAAATTCA AAACCTGAGT GTGCGCTATG ACAGCTCCCT GAAGCCCGTG 
CTGAAGCACG TCAATGCCCT CATCGCCCCA GGACAGAAGA TCGGGATCTG CGGCCGCACA 
GGCAGTGGGA AGTCCTCCTT CTCTCTCGCC TTTTTCCGAA TGGTGGACAT GTTCGAAGGG 
CGCATCATCA TTGATGGCAT CGACATCGCC AAGCTGCCGC TGCACACGCT CCGTTCACGC 
CTCTCCATCA TCCTACAGGA CCCTGTCCTC TTCAGCGGCA CCATCAGATT CAACCTGGAC 
CCAGAGAAGA AATGCTCAGA CAGCACACTC TGGGAGGCTC TGGAGATCGC CCAGCTGAAG 
CTGGTGGTGA AGGCACTGCC AGGAGGCCTG GATGCCATCA TCACAGAAGG AGGGGAGAAT 
TTTAGTCAAG GTCAGAGGCA GCTGTTCTGC CTGGCTCGGG CCTTCGTGAG AAAGACCAGC 
ATCTTCATCA TGGACGAAGC AACTGCCTCC ATTGACATGG CTACGGAAAA CATCCTCCAG 
AAGGTGGTGA TGACAGCCTT CGCAGACCGC ACTGTGGTCA CCATCGCGCA CCGCGTACAC 
ACCATCCTGA GTGCAGACCT CGTGATGGTC CTGAAGAGGG GAGCCATCCT GGAGTTTGAC 
AAACCGGAGA AGCTTCTGAG CCAGAAGGAC AGCGTCTTCG CCTCCTTCGT CCGCGCGGAC 
AAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ABCC8 ( XM_006540749.1 ) cDNA ORF clone, Mus musculus(House mouse) -> XP_006540812.1 Mus musculus ATP-binding cassette, sub-family C (CFTR/MRP), member 8 (Abcc8), transcript variant X2, mRNA.

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CloneID	OMu38749
Clone ID Related Accession (Same CDS sequence)	XM_006540749.1
Accession Version	XM_006540749.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4749bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	ATP-binding cassette sub-family C member 8 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCCTTGG CCTTCTGCGG CACCGAGAAC CACTCGGCCG CCTACCGGGT GGACCAAGGT 
GTCCTCAACA ACGGCTGCTT CGTGGACGCG CTCAACGTAG TGCCACATGT CTTCCTGCTC 
TTCATCACAT TCCCCATCCT CTTCATCGGA TGGGGCAGCC AGAGCTCCAA GGTACACATT 
CACCATAGCA CCTGGCTCCA TTTCCCTGGC CACAACCTGC GCTGGATCCT TACCTTCATG 
CTGCTCTTTG TCCTGGTGTG TGAGATCGCT GAGGGTATCC TGTCTGATGG GGTGACAGAA 
TCCCGCCACC TCCATTTGTA CATGCCAGCT GGGATGGCTT TCATGGCTGC CATCACCTCT 
GTGGTCTACT ATCACAACAT TGAGACCTCT AACTTCCCCA AGCTGCTGAT CGCTCTGCTT 
ATCTACTGGA CCTTGGCCTT CATCACTAAG ACCATCAAGT TCGTCAAGTT CTACGACCAC 
GCCATCGGCT TCTCTCAGCT GCGCTTCTGC CTCACGGGGC TTCTGGTGAT CCTCTACGGG 
ATGCTGCTGC TGGTGGAGAT CAATGTCATC CGGGTGCGGA GGTACATCTT CTTCAAGACG 
CCAAGGGAAG TGAAGCCCCC TGAGGACCTG CAGGACCTGG GGGTGCGCTT TCTGCAGCCC 
TTCGTGAATC TGCTGTCAAA GGGGACCTAC TGGTGGATGA ATGCCTTCAT CAAGACTGCC 
CACAGGAAGC CCATCGACCT GCGGGCCATC GGGAAGCTGC CCATCGCCAT GAGAGCCCTC 
ACCAACTATC AGCGACTCTG CGCGGCCTTC GATGCCCAGG CGCGGAAAGA CACGCAGAGC 
CAGCAGGGCG CCCGGGCCAT CTGGAGGGCT CTCTGCCATG CCTTTGGGAG ACGCCTGGTC 
CTCAGCAGCA CATTCCGTAT CCTGGCTGAC CTGCTGGGCT TTGCTGGACC GCTCTGCATC 
TTTGGGATCG TGGACCACCT CGGGAAGGAG AACCATGTCT TCCAGCCCAA GACACAGTTT 
CTTGGGGTTT ACTTTGTCTC GTCCCAAGAG TTCCTGGGCA ACGCCTATGT CTTGGCTGTA 
CTTCTGTTCC TGGCCCTCCT GCTGCAAAGG ACGTTCCTGC AAGCCTCGTA CTACGTCGCC 
ATTGAAACTG GGATTAACCT GAGAGGGGCG ATCCAGACCA AGATTTACAA TAAGATCATG 
CACTTGTCTA CTTCCAACCT GTCAATGGGG GAGATGACGG CTGGGCAGAT CTGCAACCTG 
GTGGCCATCG ACACAAATCA GCTCATGTGG TTTTTCTTCT TATGCCCAAA CCTCTGGGCT 
ATGCCAGTAC AGATCATTGT GGGCGTGATC CTCCTCTACT ACATCCTTGG GGTCAGTGCC 
TTGATTGGAG CAGCTGTCAT CATTCTGCTG GCTCCTGTAC AGTACTTTGT GGCCACCAAG 
CTCTCCCAGG CACAGCGGAG CACCCTGGAA TATTCCAATG AAAGGCTGAA GCAGACCAAC 
GAGATGCTCC GGGGCATCAA ACTGCTCAAA CTGTACGCGT GGGAGAACAT CTTCTGCTCG 
AGGGTGGAGA TGACGCGCAG GAAGGAAATG ACCAGCCTCA GAGCCTTCGC TGTCTACACC 
TCCATCTCCA TCTTCATGAA CACAGCTATC CCCATTGCTG CCGTCCTCAT TACCTTTGTG 
GGCCACGTCA GCTTCTTCAA AGAGTCAGAC TTCTCACCCT CGGTGGCCTT TGCCTCTCTC 
TCTCTCTTCC ACATCCTGGT CACACCGCTG TTCCTGCTGT CTAGTGTGGT TCGGTCCACC 
GTCAAGGCCC TAGTGAGTGT GCAAAAGCTG AGTGAGTTCC TGTCCAGTGC AGAGATCCGT 
GAGGAACAGT GTGCCCCCCG AGAGCCTGCA CCCCAAGGCC AAGCGGGCAA GTACCAGGCG 
GTGCCCCTCA AGGTTGTGAA CCGCAAGCGC CCAGCCCGGG AAGAGGTTCG GGACCTCTTG 
GGCCCACTGC AGAGGCTGAC CCCCAGCATG GATGGAGATG CTGACAACTT CTGTGTCCAG 
ATCATCGGAG GCTTCTTCAC CTGGACCCCT GATGGAATCC CCACCCTGTC CAACATCACC 
ATCCGTATCC CCCGAGGCCA GCTGACCATG ATTGTGGGGC AGGTGGGCTG CGGCAAGTCC 
TCGCTCCTTC TGGCCACCCT GGGGGAGATG CAGAGGGTCT CCGGGGCCGT CTTCTGGAAC 
AGCAGCCTTC CAGACAGCGA GGGAGAAGAC CCCAGCAACC CAGAGCGGGA GACAGCAGCC 
GACTCGGATG CCAGGAGCAG AGGCCCCGTA GCCTACGCAT CTCAGAAACC ATGGCTGCTA 
AATGCCACGG TGGAGGAGAA CATCACCTTC GAGAGTCCCT TCAATAAGCA AAGGTACAAG 
ATGGTCATCG AAGCCTGCTC CCTGCAGCCA GACATAGACA TCTTACCCCA TGGAGACCAG 
ACTCAGATTG GGGAACGGGG CATCAACTTG TCTGGTGGTC AGCGTCAGCG AATCAGTGTA 
GCCCGAGCCC TCTACCAGCA CACCAATGTT GTCTTCTTGG ATGACCCTTT CTCAGCTCTG 
GATGTCCATC TGAGCGACCA CCTGATGCAG GCTGGCATCC TTGAGCTGCT CCGGGATGAC 
AAGAGGACAG TGGTCTTGGT GACCCACAAG CTACAGTACC TGCCTCATGC AGACTGGATC 
ATTGCTATGA AGGATGGCAC CATTCAGAGG GAGGGGACGC TCAAGGACTT CCAGAGGTCT 
GAGTGCCAGC TCTTTGAGCA TTGGAAGACC CTCATGAACA GGCAAGACCA AGAGCTGGAG 
AAGGAGACAG TCATGGAGAG GAAAGCCCCA GAACCGTCTC AGGGCCTGCC CCGTGCCATG 
TCCTCAAGAG ATGGCCTTCT GCTGGATGAG GACGAGGAGG AAGAGGAGGC GGCCGAGAGC 
GAGGAAGATG ACAACTTATC TTCGGTGCTG CATCAGCGAG CCAAGATCCC ATGGCGGGCC 
TGCACTAAGT ATTTGTCCTC TGCCGGCGTC CTGCTCTTGT CCCTGCTTGT CTTCTCCCAG 
CTACTCAAGC ACATGGTCTT GGTGGCCATT GATTACTGGC TGGCCAAGTG GACGGACAGT 
GCCCTGGTCC TGAGCCCTGC TGCCAGGAAC TGCTCCCTCA GCCAGGAATG CGCCCTGGAC 
CAGTCTGTCT ATGCCATGGT ATTCACCGTG CTCTGCAGCC TGGGAATTGC ACTGTGCCTT 
GTCACCTCTG TCACTGTGGA GTGGACAGGA CTGAAGGTGG CCAAGAGGCT GCACCGCAGC 
CTGCTCAATC GCATCATCCT GGCCCCCATG AGGTTCTTTG AGACCACGCC CCTGGGGAGT 
ATCCTGAACA GATTTTCATC TGACTGTAAC ACCATTGACC AGCACATCCC ATCCACGCTG 
GAGTGTCTGA GCCGATCCAC TCTACTCTGT GTCTCCGCCT TGACTGTCAT CTCCTACGTC 
ACACCTGTGT TCCTCGTGGC CCTCTTACCC CTAGCTGTGG TGTGCTACTT CATCCAGAAA 
TACTTCCGAG TGGCGTCCAG GGACCTGCAG CAGCTGGATG ACACAACGCA GCTCCCTCTG 
CTCTCACACT TTGCTGAAAC CGTGGAAGGA CTCACCACCA TCCGTGCCTT CAGGTACGAG 
GCCCGGTTCC AGCAGAAGCT CCTGGAGTAC ACGGACTCCA ACAACATCGC CTCCCTCTTC 
CTCACGGCAG CCAACAGGTG GCTAGAAGTC CGCATGGAGT ACATTGGAGC ATGCGTGGTA 
CTCATCGCAG CCGCCACCTC CATCTCCAAC TCCCTGCACA GGGAGCTCTC TGCTGGTCTG 
GTGGGCCTGG GCCTCACCTA CGCCTTGATG GTCTCCAACT ACCTCAACTG GATGGTGAGG 
AACCTGGCAG ACATGGAGAT CCAATTGGGG GCTGTGAAGC GCATCCACAC ACTCCTGAAA 
ACTGAGGCAG AGAGCTATGA GGGGCTCCTA GCACCGTCAT TGATCCCCAA GAACTGGCCA 
GACCAAGGGA AGATTCAAAT TCAAAACCTG AGTGTGCGCT ATGACAGCTC CCTGAAGCCC 
GTGCTGAAGC ACGTCAATGC CCTCATCGCC CCAGGACAGA AGATCGGGAT CTGCGGCCGC 
ACAGGCAGTG GGAAGTCCTC CTTCTCTCTC GCCTTTTTCC GAATGGTGGA CATGTTCGAA 
GGGCGCATCA TCATTGATGG CATCGACATC GCCAAGCTGC CGCTGCACAC GCTCCGTTCA 
CGCCTCTCCA TCATCCTACA GGACCCTGTC CTCTTCAGCG GCACCATCAG ATTCAACCTG 
GACCCAGAGA AGAAATGCTC AGACAGCACA CTCTGGGAGG CTCTGGAGAT CGCCCAGCTG 
AAGCTGGTGG TGAAGGCACT GCCAGGAGGC CTGGATGCCA TCATCACAGA AGGAGGGGAG 
AATTTTAGTC AAGGTCAGAG GCAGCTGTTC TGCCTGGCTC GGGCCTTCGT GAGAAAGACC 
AGCATCTTCA TCATGGACGA AGCAACTGCC TCCATTGACA TGGCTACGGA AAACATCCTC 
CAGAAGGTGG TGATGACAGC CTTCGCAGAC CGCACTGTGG TCACCATCGC GCACCGCGTA 
CACACCATCC TGAGTGCAGA CCTCGTGATG GTCCTGAAGA GGGGAGCCAT CCTGGAGTTT 
GACAAACCGG AGAAGCTTCT GAGCCAGAAG GACAGCGTCT TCGCCTCCTT CGTCCGCGCG 
GACAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006540812.1
CDS	91..4839
Translation	MPLAFCGTENHSAAYRVDQGVLNNGCFVDALNVVPHVFLLFITFPILFIGWGSQSSKVHIHHSTWLHFPGHNLRWILTFMLLFVLVCEIAEGILSDGVTESRHLHLYMPAGMAFMAAITSVVYYHNIETSNFPKLLIALLIYWTLAFITKTIKFVKFYDHAIGFSQLRFCLTGLLVILYGMLLLVEINVIRVRRYIFFKTPREVKPPEDLQDLGVRFLQPFVNLLSKGTYWWMNAFIKTAHRKPIDLRAIGKLPIAMRALTNYQRLCAAFDAQARKDTQSQQGARAIWRALCHAFGRRLVLSSTFRILADLLGFAGPLCIFGIVDHLGKENHVFQPKTQFLGVYFVSSQEFLGNAYVLAVLLFLALLLQRTFLQASYYVAIETGINLRGAIQTKIYNKIMHLSTSNLSMGEMTAGQICNLVAIDTNQLMWFFFLCPNLWAMPVQIIVGVILLYYILGVSALIGAAVIILLAPVQYFVATKLSQAQRSTLEYSNERLKQTNEMLRGIKLLKLYAWENIFCSRVEMTRRKEMTSLRAFAVYTSISIFMNTAIPIAAVLITFVGHVSFFKESDFSPSVAFASLSLFHILVTPLFLLSSVVRSTVKALVSVQKLSEFLSSAEIREEQCAPREPAPQGQAGKYQAVPLKVVNRKRPAREEVRDLLGPLQRLTPSMDGDADNFCVQIIGGFFTWTPDGIPTLSNITIRIPRGQLTMIVGQVGCGKSSLLLATLGEMQRVSGAVFWNSSLPDSEGEDPSNPERETAADSDARSRGPVAYASQKPWLLNATVEENITFESPFNKQRYKMVIEACSLQPDIDILPHGDQTQIGERGINLSGGQRQRISVARALYQHTNVVFLDDPFSALDVHLSDHLMQAGILELLRDDKRTVVLVTHKLQYLPHADWIIAMKDGTIQREGTLKDFQRSECQLFEHWKTLMNRQDQELEKETVMERKAPEPSQGLPRAMSSRDGLLLDEDEEEEEAAESEEDDNLSSVLHQRAKIPWRACTKYLSSAGVLLLSLLVFSQLLKHMVLVAIDYWLAKWTDSALVLSPAARNCSLSQECALDQSVYAMVFTVLCSLGIALCLVTSVTVEWTGLKVAKRLHRSLLNRIILAPMRFFETTPLGSILNRFSSDCNTIDQHIPSTLECLSRSTLLCVSALTVISYVTPVFLVALLPLAVVCYFIQKYFRVASRDLQQLDDTTQLPLLSHFAETVEGLTTIRAFRYEARFQQKLLEYTDSNNIASLFLTAANRWLEVRMEYIGACVVLIAAATSISNSLHRELSAGLVGLGLTYALMVSNYLNWMVRNLADMEIQLGAVKRIHTLLKTEAESYEGLLAPSLIPKNWPDQGKIQIQNLSVRYDSSLKPVLKHVNALIAPGQKIGICGRTGSGKSSFSLAFFRMVDMFEGRIIIDGIDIAKLPLHTLRSRLSIILQDPVLFSGTIRFNLDPEKKCSDSTLWEALEIAQLKLVVKALPGGLDAIITEGGENFSQGQRQLFCLARAFVRKTSIFIMDEATASIDMATENILQKVVMTAFADRTVVTIAHRVHTILSADLVMVLKRGAILEFDKPEKLLSQKDSVFASFVRADK

Target ORF information:

RefSeq Version	XM_006540749.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus ATP-binding cassette, sub-family C (CFTR/MRP), member 8 (Abcc8), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006540749.1

ORF Insert Sequence:

ATGCCCTTGG CCTTCTGCGG CACCGAGAAC CACTCGGCCG CCTACCGGGT GGACCAAGGT 
GTCCTCAACA ACGGCTGCTT CGTGGACGCG CTCAACGTAG TGCCACATGT CTTCCTGCTC 
TTCATCACAT TCCCCATCCT CTTCATCGGA TGGGGCAGCC AGAGCTCCAA GGTACACATT 
CACCATAGCA CCTGGCTCCA TTTCCCTGGC CACAACCTGC GCTGGATCCT TACCTTCATG 
CTGCTCTTTG TCCTGGTGTG TGAGATCGCT GAGGGTATCC TGTCTGATGG GGTGACAGAA 
TCCCGCCACC TCCATTTGTA CATGCCAGCT GGGATGGCTT TCATGGCTGC CATCACCTCT 
GTGGTCTACT ATCACAACAT TGAGACCTCT AACTTCCCCA AGCTGCTGAT CGCTCTGCTT 
ATCTACTGGA CCTTGGCCTT CATCACTAAG ACCATCAAGT TCGTCAAGTT CTACGACCAC 
GCCATCGGCT TCTCTCAGCT GCGCTTCTGC CTCACGGGGC TTCTGGTGAT CCTCTACGGG 
ATGCTGCTGC TGGTGGAGAT CAATGTCATC CGGGTGCGGA GGTACATCTT CTTCAAGACG 
CCAAGGGAAG TGAAGCCCCC TGAGGACCTG CAGGACCTGG GGGTGCGCTT TCTGCAGCCC 
TTCGTGAATC TGCTGTCAAA GGGGACCTAC TGGTGGATGA ATGCCTTCAT CAAGACTGCC 
CACAGGAAGC CCATCGACCT GCGGGCCATC GGGAAGCTGC CCATCGCCAT GAGAGCCCTC 
ACCAACTATC AGCGACTCTG CGCGGCCTTC GATGCCCAGG CGCGGAAAGA CACGCAGAGC 
CAGCAGGGCG CCCGGGCCAT CTGGAGGGCT CTCTGCCATG CCTTTGGGAG ACGCCTGGTC 
CTCAGCAGCA CATTCCGTAT CCTGGCTGAC CTGCTGGGCT TTGCTGGACC GCTCTGCATC 
TTTGGGATCG TGGACCACCT CGGGAAGGAG AACCATGTCT TCCAGCCCAA GACACAGTTT 
CTTGGGGTTT ACTTTGTCTC GTCCCAAGAG TTCCTGGGCA ACGCCTATGT CTTGGCTGTA 
CTTCTGTTCC TGGCCCTCCT GCTGCAAAGG ACGTTCCTGC AAGCCTCGTA CTACGTCGCC 
ATTGAAACTG GGATTAACCT GAGAGGGGCG ATCCAGACCA AGATTTACAA TAAGATCATG 
CACTTGTCTA CTTCCAACCT GTCAATGGGG GAGATGACGG CTGGGCAGAT CTGCAACCTG 
GTGGCCATCG ACACAAATCA GCTCATGTGG TTTTTCTTCT TATGCCCAAA CCTCTGGGCT 
ATGCCAGTAC AGATCATTGT GGGCGTGATC CTCCTCTACT ACATCCTTGG GGTCAGTGCC 
TTGATTGGAG CAGCTGTCAT CATTCTGCTG GCTCCTGTAC AGTACTTTGT GGCCACCAAG 
CTCTCCCAGG CACAGCGGAG CACCCTGGAA TATTCCAATG AAAGGCTGAA GCAGACCAAC 
GAGATGCTCC GGGGCATCAA ACTGCTCAAA CTGTACGCGT GGGAGAACAT CTTCTGCTCG 
AGGGTGGAGA TGACGCGCAG GAAGGAAATG ACCAGCCTCA GAGCCTTCGC TGTCTACACC 
TCCATCTCCA TCTTCATGAA CACAGCTATC CCCATTGCTG CCGTCCTCAT TACCTTTGTG 
GGCCACGTCA GCTTCTTCAA AGAGTCAGAC TTCTCACCCT CGGTGGCCTT TGCCTCTCTC 
TCTCTCTTCC ACATCCTGGT CACACCGCTG TTCCTGCTGT CTAGTGTGGT TCGGTCCACC 
GTCAAGGCCC TAGTGAGTGT GCAAAAGCTG AGTGAGTTCC TGTCCAGTGC AGAGATCCGT 
GAGGAACAGT GTGCCCCCCG AGAGCCTGCA CCCCAAGGCC AAGCGGGCAA GTACCAGGCG 
GTGCCCCTCA AGGTTGTGAA CCGCAAGCGC CCAGCCCGGG AAGAGGTTCG GGACCTCTTG 
GGCCCACTGC AGAGGCTGAC CCCCAGCATG GATGGAGATG CTGACAACTT CTGTGTCCAG 
ATCATCGGAG GCTTCTTCAC CTGGACCCCT GATGGAATCC CCACCCTGTC CAACATCACC 
ATCCGTATCC CCCGAGGCCA GCTGACCATG ATTGTGGGGC AGGTGGGCTG CGGCAAGTCC 
TCGCTCCTTC TGGCCACCCT GGGGGAGATG CAGAGGGTCT CCGGGGCCGT CTTCTGGAAC 
AGCAGCCTTC CAGACAGCGA GGGAGAAGAC CCCAGCAACC CAGAGCGGGA GACAGCAGCC 
GACTCGGATG CCAGGAGCAG AGGCCCCGTA GCCTACGCAT CTCAGAAACC ATGGCTGCTA 
AATGCCACGG TGGAGGAGAA CATCACCTTC GAGAGTCCCT TCAATAAGCA AAGGTACAAG 
ATGGTCATCG AAGCCTGCTC CCTGCAGCCA GACATAGACA TCTTACCCCA TGGAGACCAG 
ACTCAGATTG GGGAACGGGG CATCAACTTG TCTGGTGGTC AGCGTCAGCG AATCAGTGTA 
GCCCGAGCCC TCTACCAGCA CACCAATGTT GTCTTCTTGG ATGACCCTTT CTCAGCTCTG 
GATGTCCATC TGAGCGACCA CCTGATGCAG GCTGGCATCC TTGAGCTGCT CCGGGATGAC 
AAGAGGACAG TGGTCTTGGT GACCCACAAG CTACAGTACC TGCCTCATGC AGACTGGATC 
ATTGCTATGA AGGATGGCAC CATTCAGAGG GAGGGGACGC TCAAGGACTT CCAGAGGTCT 
GAGTGCCAGC TCTTTGAGCA TTGGAAGACC CTCATGAACA GGCAAGACCA AGAGCTGGAG 
AAGGAGACAG TCATGGAGAG GAAAGCCCCA GAACCGTCTC AGGGCCTGCC CCGTGCCATG 
TCCTCAAGAG ATGGCCTTCT GCTGGATGAG GACGAGGAGG AAGAGGAGGC GGCCGAGAGC 
GAGGAAGATG ACAACTTATC TTCGGTGCTG CATCAGCGAG CCAAGATCCC ATGGCGGGCC 
TGCACTAAGT ATTTGTCCTC TGCCGGCGTC CTGCTCTTGT CCCTGCTTGT CTTCTCCCAG 
CTACTCAAGC ACATGGTCTT GGTGGCCATT GATTACTGGC TGGCCAAGTG GACGGACAGT 
GCCCTGGTCC TGAGCCCTGC TGCCAGGAAC TGCTCCCTCA GCCAGGAATG CGCCCTGGAC 
CAGTCTGTCT ATGCCATGGT ATTCACCGTG CTCTGCAGCC TGGGAATTGC ACTGTGCCTT 
GTCACCTCTG TCACTGTGGA GTGGACAGGA CTGAAGGTGG CCAAGAGGCT GCACCGCAGC 
CTGCTCAATC GCATCATCCT GGCCCCCATG AGGTTCTTTG AGACCACGCC CCTGGGGAGT 
ATCCTGAACA GATTTTCATC TGACTGTAAC ACCATTGACC AGCACATCCC ATCCACGCTG 
GAGTGTCTGA GCCGATCCAC TCTACTCTGT GTCTCCGCCT TGACTGTCAT CTCCTACGTC 
ACACCTGTGT TCCTCGTGGC CCTCTTACCC CTAGCTGTGG TGTGCTACTT CATCCAGAAA 
TACTTCCGAG TGGCGTCCAG GGACCTGCAG CAGCTGGATG ACACAACGCA GCTCCCTCTG 
CTCTCACACT TTGCTGAAAC CGTGGAAGGA CTCACCACCA TCCGTGCCTT CAGGTACGAG 
GCCCGGTTCC AGCAGAAGCT CCTGGAGTAC ACGGACTCCA ACAACATCGC CTCCCTCTTC 
CTCACGGCAG CCAACAGGTG GCTAGAAGTC CGCATGGAGT ACATTGGAGC ATGCGTGGTA 
CTCATCGCAG CCGCCACCTC CATCTCCAAC TCCCTGCACA GGGAGCTCTC TGCTGGTCTG 
GTGGGCCTGG GCCTCACCTA CGCCTTGATG GTCTCCAACT ACCTCAACTG GATGGTGAGG 
AACCTGGCAG ACATGGAGAT CCAATTGGGG GCTGTGAAGC GCATCCACAC ACTCCTGAAA 
ACTGAGGCAG AGAGCTATGA GGGGCTCCTA GCACCGTCAT TGATCCCCAA GAACTGGCCA 
GACCAAGGGA AGATTCAAAT TCAAAACCTG AGTGTGCGCT ATGACAGCTC CCTGAAGCCC 
GTGCTGAAGC ACGTCAATGC CCTCATCGCC CCAGGACAGA AGATCGGGAT CTGCGGCCGC 
ACAGGCAGTG GGAAGTCCTC CTTCTCTCTC GCCTTTTTCC GAATGGTGGA CATGTTCGAA 
GGGCGCATCA TCATTGATGG CATCGACATC GCCAAGCTGC CGCTGCACAC GCTCCGTTCA 
CGCCTCTCCA TCATCCTACA GGACCCTGTC CTCTTCAGCG GCACCATCAG ATTCAACCTG 
GACCCAGAGA AGAAATGCTC AGACAGCACA CTCTGGGAGG CTCTGGAGAT CGCCCAGCTG 
AAGCTGGTGG TGAAGGCACT GCCAGGAGGC CTGGATGCCA TCATCACAGA AGGAGGGGAG 
AATTTTAGTC AAGGTCAGAG GCAGCTGTTC TGCCTGGCTC GGGCCTTCGT GAGAAAGACC 
AGCATCTTCA TCATGGACGA AGCAACTGCC TCCATTGACA TGGCTACGGA AAACATCCTC 
CAGAAGGTGG TGATGACAGC CTTCGCAGAC CGCACTGTGG TCACCATCGC GCACCGCGTA 
CACACCATCC TGAGTGCAGA CCTCGTGATG GTCCTGAAGA GGGGAGCCAT CCTGGAGTTT 
GACAAACCGG AGAAGCTTCT GAGCCAGAAG GACAGCGTCT TCGCCTCCTT CGTCCGCGCG 
GACAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ABCC8 ( XM_006540750.1 ) cDNA ORF clone, Mus musculus(House mouse) -> XP_006540813.1 Mus musculus ATP-binding cassette, sub-family C (CFTR/MRP), member 8 (Abcc8), transcript variant X5, mRNA.

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CloneID	OMu38750
Clone ID Related Accession (Same CDS sequence)	NM_001357538.1 , XM_006540750.1
Accession Version	XM_006540750.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4746bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(House mouse)
Product	ATP-binding cassette sub-family C member 8 isoform X2
Comment	MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCCTTGG CCTTCTGCGG CACCGAGAAC CACTCGGCCG CCTACCGGGT GGACCAAGGT 
GTCCTCAACA ACGGCTGCTT CGTGGACGCG CTCAACGTAG TGCCACATGT CTTCCTGCTC 
TTCATCACAT TCCCCATCCT CTTCATCGGA TGGGGCAGCC AGAGCTCCAA GGTACACATT 
CACCATAGCA CCTGGCTCCA TTTCCCTGGC CACAACCTGC GCTGGATCCT TACCTTCATG 
CTGCTCTTTG TCCTGGTGTG TGAGATCGCT GAGGGTATCC TGTCTGATGG GGTGACAGAA 
TCCCGCCACC TCCATTTGTA CATGCCAGCT GGGATGGCTT TCATGGCTGC CATCACCTCT 
GTGGTCTACT ATCACAACAT TGAGACCTCT AACTTCCCCA AGCTGCTGAT CGCTCTGCTT 
ATCTACTGGA CCTTGGCCTT CATCACTAAG ACCATCAAGT TCGTCAAGTT CTACGACCAC 
GCCATCGGCT TCTCTCAGCT GCGCTTCTGC CTCACGGGGC TTCTGGTGAT CCTCTACGGG 
ATGCTGCTGC TGGTGGAGAT CAATGTCATC CGGGTGCGGA GGTACATCTT CTTCAAGACG 
CCAAGGGAAG TGAAGCCCCC TGAGGACCTG CAGGACCTGG GGGTGCGCTT TCTGCAGCCC 
TTCGTGAATC TGCTGTCAAA GGGGACCTAC TGGTGGATGA ATGCCTTCAT CAAGACTGCC 
CACAGGAAGC CCATCGACCT GCGGGCCATC GGGAAGCTGC CCATCGCCAT GAGAGCCCTC 
ACCAACTATC AGCGACTCTG CGCGGCCTTC GATGCCCAGG CGCGGAAAGA CACGCAGAGC 
CAGCAGGGCG CCCGGGCCAT CTGGAGGGCT CTCTGCCATG CCTTTGGGAG ACGCCTGGTC 
CTCAGCAGCA CATTCCGTAT CCTGGCTGAC CTGCTGGGCT TTGCTGGACC GCTCTGCATC 
TTTGGGATCG TGGACCACCT CGGGAAGGAG AACCATGTCT TCCAGCCCAA GACACAGTTT 
CTTGGGGTTT ACTTTGTCTC GTCCCAAGAG TTCCTGGGCA ACGCCTATGT CTTGGCTGTA 
CTTCTGTTCC TGGCCCTCCT GCTGCAAAGG ACGTTCCTGC AAGCCTCGTA CTACGTCGCC 
ATTGAAACTG GGATTAACCT GAGAGGGGCG ATCCAGACCA AGATTTACAA TAAGATCATG 
CACTTGTCTA CTTCCAACCT GTCAATGGGG GAGATGACGG CTGGGCAGAT CTGCAACCTG 
GTGGCCATCG ACACAAATCA GCTCATGTGG TTTTTCTTCT TATGCCCAAA CCTCTGGGCT 
ATGCCAGTAC AGATCATTGT GGGCGTGATC CTCCTCTACT ACATCCTTGG GGTCAGTGCC 
TTGATTGGAG CAGCTGTCAT CATTCTGCTG GCTCCTGTAC AGTACTTTGT GGCCACCAAG 
CTCTCCCAGG CACAGCGGAG CACCCTGGAA TATTCCAATG AAAGGCTGAA GCAGACCAAC 
GAGATGCTCC GGGGCATCAA ACTGCTCAAA CTGTACGCGT GGGAGAACAT CTTCTGCTCG 
AGGGTGGAGA TGACGCGCAG GAAGGAAATG ACCAGCCTCA GAGCCTTCGC TGTCTACACC 
TCCATCTCCA TCTTCATGAA CACAGCTATC CCCATTGCTG CCGTCCTCAT TACCTTTGTG 
GGCCACGTCA GCTTCTTCAA AGAGTCAGAC TTCTCACCCT CGGTGGCCTT TGCCTCTCTC 
TCTCTCTTCC ACATCCTGGT CACACCGCTG TTCCTGCTGT CTAGTGTGGT TCGGTCCACC 
GTCAAGGCCC TAGTGAGTGT GCAAAAGCTG AGTGAGTTCC TGTCCAGTGC AGAGATCCGT 
GAGGAACAGT GTGCCCCCCG AGAGCCTGCA CCCCAAGGCC AAGCGGGCAA GTACCAGGCG 
GTGCCCCTCA AGGTTGTGAA CCGCAAGCGC CCAGCCCGGG AAGAGGTTCG GGACCTCTTG 
GGCCCACTGC AGAGGCTGAC CCCCAGCATG GATGGAGATG CTGACAACTT CTGTGTCCAG 
ATCATCGGAG GCTTCTTCAC CTGGACCCCT GATGGAATCC CCACCCTGTC CAACATCACC 
ATCCGTATCC CCCGAGGCCA GCTGACCATG ATTGTGGGGC AGGTGGGCTG CGGCAAGTCC 
TCGCTCCTTC TGGCCACCCT GGGGGAGATG CAGAGGGTCT CCGGGGCCGT CTTCTGGAAC 
AGCCTTCCAG ACAGCGAGGG AGAAGACCCC AGCAACCCAG AGCGGGAGAC AGCAGCCGAC 
TCGGATGCCA GGAGCAGAGG CCCCGTAGCC TACGCATCTC AGAAACCATG GCTGCTAAAT 
GCCACGGTGG AGGAGAACAT CACCTTCGAG AGTCCCTTCA ATAAGCAAAG GTACAAGATG 
GTCATCGAAG CCTGCTCCCT GCAGCCAGAC ATAGACATCT TACCCCATGG AGACCAGACT 
CAGATTGGGG AACGGGGCAT CAACTTGTCT GGTGGTCAGC GTCAGCGAAT CAGTGTAGCC 
CGAGCCCTCT ACCAGCACAC CAATGTTGTC TTCTTGGATG ACCCTTTCTC AGCTCTGGAT 
GTCCATCTGA GCGACCACCT GATGCAGGCT GGCATCCTTG AGCTGCTCCG GGATGACAAG 
AGGACAGTGG TCTTGGTGAC CCACAAGCTA CAGTACCTGC CTCATGCAGA CTGGATCATT 
GCTATGAAGG ATGGCACCAT TCAGAGGGAG GGGACGCTCA AGGACTTCCA GAGGTCTGAG 
TGCCAGCTCT TTGAGCATTG GAAGACCCTC ATGAACAGGC AAGACCAAGA GCTGGAGAAG 
GAGACAGTCA TGGAGAGGAA AGCCCCAGAA CCGTCTCAGG GCCTGCCCCG TGCCATGTCC 
TCAAGAGATG GCCTTCTGCT GGATGAGGAC GAGGAGGAAG AGGAGGCGGC CGAGAGCGAG 
GAAGATGACA ACTTATCTTC GGTGCTGCAT CAGCGAGCCA AGATCCCATG GCGGGCCTGC 
ACTAAGTATT TGTCCTCTGC CGGCGTCCTG CTCTTGTCCC TGCTTGTCTT CTCCCAGCTA 
CTCAAGCACA TGGTCTTGGT GGCCATTGAT TACTGGCTGG CCAAGTGGAC GGACAGTGCC 
CTGGTCCTGA GCCCTGCTGC CAGGAACTGC TCCCTCAGCC AGGAATGCGC CCTGGACCAG 
TCTGTCTATG CCATGGTATT CACCGTGCTC TGCAGCCTGG GAATTGCACT GTGCCTTGTC 
ACCTCTGTCA CTGTGGAGTG GACAGGACTG AAGGTGGCCA AGAGGCTGCA CCGCAGCCTG 
CTCAATCGCA TCATCCTGGC CCCCATGAGG TTCTTTGAGA CCACGCCCCT GGGGAGTATC 
CTGAACAGAT TTTCATCTGA CTGTAACACC ATTGACCAGC ACATCCCATC CACGCTGGAG 
TGTCTGAGCC GATCCACTCT ACTCTGTGTC TCCGCCTTGA CTGTCATCTC CTACGTCACA 
CCTGTGTTCC TCGTGGCCCT CTTACCCCTA GCTGTGGTGT GCTACTTCAT CCAGAAATAC 
TTCCGAGTGG CGTCCAGGGA CCTGCAGCAG CTGGATGACA CAACGCAGCT CCCTCTGCTC 
TCACACTTTG CTGAAACCGT GGAAGGACTC ACCACCATCC GTGCCTTCAG GTACGAGGCC 
CGGTTCCAGC AGAAGCTCCT GGAGTACACG GACTCCAACA ACATCGCCTC CCTCTTCCTC 
ACGGCAGCCA ACAGGTGGCT AGAAGTCCGC ATGGAGTACA TTGGAGCATG CGTGGTACTC 
ATCGCAGCCG CCACCTCCAT CTCCAACTCC CTGCACAGGG AGCTCTCTGC TGGTCTGGTG 
GGCCTGGGCC TCACCTACGC CTTGATGGTC TCCAACTACC TCAACTGGAT GGTGAGGAAC 
CTGGCAGACA TGGAGATCCA ATTGGGGGCT GTGAAGCGCA TCCACACACT CCTGAAAACT 
GAGGCAGAGA GCTATGAGGG GCTCCTAGCA CCGTCATTGA TCCCCAAGAA CTGGCCAGAC 
CAAGGGAAGA TTCAAATTCA AAACCTGAGT GTGCGCTATG ACAGCTCCCT GAAGCCCGTG 
CTGAAGCACG TCAATGCCCT CATCGCCCCA GGACAGAAGA TCGGGATCTG CGGCCGCACA 
GGCAGTGGGA AGTCCTCCTT CTCTCTCGCC TTTTTCCGAA TGGTGGACAT GTTCGAAGGG 
CGCATCATCA TTGATGGCAT CGACATCGCC AAGCTGCCGC TGCACACGCT CCGTTCACGC 
CTCTCCATCA TCCTACAGGA CCCTGTCCTC TTCAGCGGCA CCATCAGATT CAACCTGGAC 
CCAGAGAAGA AATGCTCAGA CAGCACACTC TGGGAGGCTC TGGAGATCGC CCAGCTGAAG 
CTGGTGGTGA AGGCACTGCC AGGAGGCCTG GATGCCATCA TCACAGAAGG AGGGGAGAAT 
TTTAGTCAAG GTCAGAGGCA GCTGTTCTGC CTGGCTCGGG CCTTCGTGAG AAAGACCAGC 
ATCTTCATCA TGGACGAAGC AACTGCCTCC ATTGACATGG CTACGGAAAA CATCCTCCAG 
AAGGTGGTGA TGACAGCCTT CGCAGACCGC ACTGTGGTCA CCATCGCGCA CCGCGTACAC 
ACCATCCTGA GTGCAGACCT CGTGATGGTC CTGAAGAGGG GAGCCATCCT GGAGTTTGAC 
AAACCGGAGA AGCTTCTGAG CCAGAAGGAC AGCGTCTTCG CCTCCTTCGT CCGCGCGGAC 
AAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006540813.1
CDS	91..4836
Translation	MPLAFCGTENHSAAYRVDQGVLNNGCFVDALNVVPHVFLLFITFPILFIGWGSQSSKVHIHHSTWLHFPGHNLRWILTFMLLFVLVCEIAEGILSDGVTESRHLHLYMPAGMAFMAAITSVVYYHNIETSNFPKLLIALLIYWTLAFITKTIKFVKFYDHAIGFSQLRFCLTGLLVILYGMLLLVEINVIRVRRYIFFKTPREVKPPEDLQDLGVRFLQPFVNLLSKGTYWWMNAFIKTAHRKPIDLRAIGKLPIAMRALTNYQRLCAAFDAQARKDTQSQQGARAIWRALCHAFGRRLVLSSTFRILADLLGFAGPLCIFGIVDHLGKENHVFQPKTQFLGVYFVSSQEFLGNAYVLAVLLFLALLLQRTFLQASYYVAIETGINLRGAIQTKIYNKIMHLSTSNLSMGEMTAGQICNLVAIDTNQLMWFFFLCPNLWAMPVQIIVGVILLYYILGVSALIGAAVIILLAPVQYFVATKLSQAQRSTLEYSNERLKQTNEMLRGIKLLKLYAWENIFCSRVEMTRRKEMTSLRAFAVYTSISIFMNTAIPIAAVLITFVGHVSFFKESDFSPSVAFASLSLFHILVTPLFLLSSVVRSTVKALVSVQKLSEFLSSAEIREEQCAPREPAPQGQAGKYQAVPLKVVNRKRPAREEVRDLLGPLQRLTPSMDGDADNFCVQIIGGFFTWTPDGIPTLSNITIRIPRGQLTMIVGQVGCGKSSLLLATLGEMQRVSGAVFWNSLPDSEGEDPSNPERETAADSDARSRGPVAYASQKPWLLNATVEENITFESPFNKQRYKMVIEACSLQPDIDILPHGDQTQIGERGINLSGGQRQRISVARALYQHTNVVFLDDPFSALDVHLSDHLMQAGILELLRDDKRTVVLVTHKLQYLPHADWIIAMKDGTIQREGTLKDFQRSECQLFEHWKTLMNRQDQELEKETVMERKAPEPSQGLPRAMSSRDGLLLDEDEEEEEAAESEEDDNLSSVLHQRAKIPWRACTKYLSSAGVLLLSLLVFSQLLKHMVLVAIDYWLAKWTDSALVLSPAARNCSLSQECALDQSVYAMVFTVLCSLGIALCLVTSVTVEWTGLKVAKRLHRSLLNRIILAPMRFFETTPLGSILNRFSSDCNTIDQHIPSTLECLSRSTLLCVSALTVISYVTPVFLVALLPLAVVCYFIQKYFRVASRDLQQLDDTTQLPLLSHFAETVEGLTTIRAFRYEARFQQKLLEYTDSNNIASLFLTAANRWLEVRMEYIGACVVLIAAATSISNSLHRELSAGLVGLGLTYALMVSNYLNWMVRNLADMEIQLGAVKRIHTLLKTEAESYEGLLAPSLIPKNWPDQGKIQIQNLSVRYDSSLKPVLKHVNALIAPGQKIGICGRTGSGKSSFSLAFFRMVDMFEGRIIIDGIDIAKLPLHTLRSRLSIILQDPVLFSGTIRFNLDPEKKCSDSTLWEALEIAQLKLVVKALPGGLDAIITEGGENFSQGQRQLFCLARAFVRKTSIFIMDEATASIDMATENILQKVVMTAFADRTVVTIAHRVHTILSADLVMVLKRGAILEFDKPEKLLSQKDSVFASFVRADK

Target ORF information:

RefSeq Version	XM_006540750.1
Organism	Mus musculus(House mouse)
Definition	Mus musculus ATP-binding cassette, sub-family C (CFTR/MRP), member 8 (Abcc8), transcript variant X5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006540750.1

ORF Insert Sequence:

ATGCCCTTGG CCTTCTGCGG CACCGAGAAC CACTCGGCCG CCTACCGGGT GGACCAAGGT 
GTCCTCAACA ACGGCTGCTT CGTGGACGCG CTCAACGTAG TGCCACATGT CTTCCTGCTC 
TTCATCACAT TCCCCATCCT CTTCATCGGA TGGGGCAGCC AGAGCTCCAA GGTACACATT 
CACCATAGCA CCTGGCTCCA TTTCCCTGGC CACAACCTGC GCTGGATCCT TACCTTCATG 
CTGCTCTTTG TCCTGGTGTG TGAGATCGCT GAGGGTATCC TGTCTGATGG GGTGACAGAA 
TCCCGCCACC TCCATTTGTA CATGCCAGCT GGGATGGCTT TCATGGCTGC CATCACCTCT 
GTGGTCTACT ATCACAACAT TGAGACCTCT AACTTCCCCA AGCTGCTGAT CGCTCTGCTT 
ATCTACTGGA CCTTGGCCTT CATCACTAAG ACCATCAAGT TCGTCAAGTT CTACGACCAC 
GCCATCGGCT TCTCTCAGCT GCGCTTCTGC CTCACGGGGC TTCTGGTGAT CCTCTACGGG 
ATGCTGCTGC TGGTGGAGAT CAATGTCATC CGGGTGCGGA GGTACATCTT CTTCAAGACG 
CCAAGGGAAG TGAAGCCCCC TGAGGACCTG CAGGACCTGG GGGTGCGCTT TCTGCAGCCC 
TTCGTGAATC TGCTGTCAAA GGGGACCTAC TGGTGGATGA ATGCCTTCAT CAAGACTGCC 
CACAGGAAGC CCATCGACCT GCGGGCCATC GGGAAGCTGC CCATCGCCAT GAGAGCCCTC 
ACCAACTATC AGCGACTCTG CGCGGCCTTC GATGCCCAGG CGCGGAAAGA CACGCAGAGC 
CAGCAGGGCG CCCGGGCCAT CTGGAGGGCT CTCTGCCATG CCTTTGGGAG ACGCCTGGTC 
CTCAGCAGCA CATTCCGTAT CCTGGCTGAC CTGCTGGGCT TTGCTGGACC GCTCTGCATC 
TTTGGGATCG TGGACCACCT CGGGAAGGAG AACCATGTCT TCCAGCCCAA GACACAGTTT 
CTTGGGGTTT ACTTTGTCTC GTCCCAAGAG TTCCTGGGCA ACGCCTATGT CTTGGCTGTA 
CTTCTGTTCC TGGCCCTCCT GCTGCAAAGG ACGTTCCTGC AAGCCTCGTA CTACGTCGCC 
ATTGAAACTG GGATTAACCT GAGAGGGGCG ATCCAGACCA AGATTTACAA TAAGATCATG 
CACTTGTCTA CTTCCAACCT GTCAATGGGG GAGATGACGG CTGGGCAGAT CTGCAACCTG 
GTGGCCATCG ACACAAATCA GCTCATGTGG TTTTTCTTCT TATGCCCAAA CCTCTGGGCT 
ATGCCAGTAC AGATCATTGT GGGCGTGATC CTCCTCTACT ACATCCTTGG GGTCAGTGCC 
TTGATTGGAG CAGCTGTCAT CATTCTGCTG GCTCCTGTAC AGTACTTTGT GGCCACCAAG 
CTCTCCCAGG CACAGCGGAG CACCCTGGAA TATTCCAATG AAAGGCTGAA GCAGACCAAC 
GAGATGCTCC GGGGCATCAA ACTGCTCAAA CTGTACGCGT GGGAGAACAT CTTCTGCTCG 
AGGGTGGAGA TGACGCGCAG GAAGGAAATG ACCAGCCTCA GAGCCTTCGC TGTCTACACC 
TCCATCTCCA TCTTCATGAA CACAGCTATC CCCATTGCTG CCGTCCTCAT TACCTTTGTG 
GGCCACGTCA GCTTCTTCAA AGAGTCAGAC TTCTCACCCT CGGTGGCCTT TGCCTCTCTC 
TCTCTCTTCC ACATCCTGGT CACACCGCTG TTCCTGCTGT CTAGTGTGGT TCGGTCCACC 
GTCAAGGCCC TAGTGAGTGT GCAAAAGCTG AGTGAGTTCC TGTCCAGTGC AGAGATCCGT 
GAGGAACAGT GTGCCCCCCG AGAGCCTGCA CCCCAAGGCC AAGCGGGCAA GTACCAGGCG 
GTGCCCCTCA AGGTTGTGAA CCGCAAGCGC CCAGCCCGGG AAGAGGTTCG GGACCTCTTG 
GGCCCACTGC AGAGGCTGAC CCCCAGCATG GATGGAGATG CTGACAACTT CTGTGTCCAG 
ATCATCGGAG GCTTCTTCAC CTGGACCCCT GATGGAATCC CCACCCTGTC CAACATCACC 
ATCCGTATCC CCCGAGGCCA GCTGACCATG ATTGTGGGGC AGGTGGGCTG CGGCAAGTCC 
TCGCTCCTTC TGGCCACCCT GGGGGAGATG CAGAGGGTCT CCGGGGCCGT CTTCTGGAAC 
AGCCTTCCAG ACAGCGAGGG AGAAGACCCC AGCAACCCAG AGCGGGAGAC AGCAGCCGAC 
TCGGATGCCA GGAGCAGAGG CCCCGTAGCC TACGCATCTC AGAAACCATG GCTGCTAAAT 
GCCACGGTGG AGGAGAACAT CACCTTCGAG AGTCCCTTCA ATAAGCAAAG GTACAAGATG 
GTCATCGAAG CCTGCTCCCT GCAGCCAGAC ATAGACATCT TACCCCATGG AGACCAGACT 
CAGATTGGGG AACGGGGCAT CAACTTGTCT GGTGGTCAGC GTCAGCGAAT CAGTGTAGCC 
CGAGCCCTCT ACCAGCACAC CAATGTTGTC TTCTTGGATG ACCCTTTCTC AGCTCTGGAT 
GTCCATCTGA GCGACCACCT GATGCAGGCT GGCATCCTTG AGCTGCTCCG GGATGACAAG 
AGGACAGTGG TCTTGGTGAC CCACAAGCTA CAGTACCTGC CTCATGCAGA CTGGATCATT 
GCTATGAAGG ATGGCACCAT TCAGAGGGAG GGGACGCTCA AGGACTTCCA GAGGTCTGAG 
TGCCAGCTCT TTGAGCATTG GAAGACCCTC ATGAACAGGC AAGACCAAGA GCTGGAGAAG 
GAGACAGTCA TGGAGAGGAA AGCCCCAGAA CCGTCTCAGG GCCTGCCCCG TGCCATGTCC 
TCAAGAGATG GCCTTCTGCT GGATGAGGAC GAGGAGGAAG AGGAGGCGGC CGAGAGCGAG 
GAAGATGACA ACTTATCTTC GGTGCTGCAT CAGCGAGCCA AGATCCCATG GCGGGCCTGC 
ACTAAGTATT TGTCCTCTGC CGGCGTCCTG CTCTTGTCCC TGCTTGTCTT CTCCCAGCTA 
CTCAAGCACA TGGTCTTGGT GGCCATTGAT TACTGGCTGG CCAAGTGGAC GGACAGTGCC 
CTGGTCCTGA GCCCTGCTGC CAGGAACTGC TCCCTCAGCC AGGAATGCGC CCTGGACCAG 
TCTGTCTATG CCATGGTATT CACCGTGCTC TGCAGCCTGG GAATTGCACT GTGCCTTGTC 
ACCTCTGTCA CTGTGGAGTG GACAGGACTG AAGGTGGCCA AGAGGCTGCA CCGCAGCCTG 
CTCAATCGCA TCATCCTGGC CCCCATGAGG TTCTTTGAGA CCACGCCCCT GGGGAGTATC 
CTGAACAGAT TTTCATCTGA CTGTAACACC ATTGACCAGC ACATCCCATC CACGCTGGAG 
TGTCTGAGCC GATCCACTCT ACTCTGTGTC TCCGCCTTGA CTGTCATCTC CTACGTCACA 
CCTGTGTTCC TCGTGGCCCT CTTACCCCTA GCTGTGGTGT GCTACTTCAT CCAGAAATAC 
TTCCGAGTGG CGTCCAGGGA CCTGCAGCAG CTGGATGACA CAACGCAGCT CCCTCTGCTC 
TCACACTTTG CTGAAACCGT GGAAGGACTC ACCACCATCC GTGCCTTCAG GTACGAGGCC 
CGGTTCCAGC AGAAGCTCCT GGAGTACACG GACTCCAACA ACATCGCCTC CCTCTTCCTC 
ACGGCAGCCA ACAGGTGGCT AGAAGTCCGC ATGGAGTACA TTGGAGCATG CGTGGTACTC 
ATCGCAGCCG CCACCTCCAT CTCCAACTCC CTGCACAGGG AGCTCTCTGC TGGTCTGGTG 
GGCCTGGGCC TCACCTACGC CTTGATGGTC TCCAACTACC TCAACTGGAT GGTGAGGAAC 
CTGGCAGACA TGGAGATCCA ATTGGGGGCT GTGAAGCGCA TCCACACACT CCTGAAAACT 
GAGGCAGAGA GCTATGAGGG GCTCCTAGCA CCGTCATTGA TCCCCAAGAA CTGGCCAGAC 
CAAGGGAAGA TTCAAATTCA AAACCTGAGT GTGCGCTATG ACAGCTCCCT GAAGCCCGTG 
CTGAAGCACG TCAATGCCCT CATCGCCCCA GGACAGAAGA TCGGGATCTG CGGCCGCACA 
GGCAGTGGGA AGTCCTCCTT CTCTCTCGCC TTTTTCCGAA TGGTGGACAT GTTCGAAGGG 
CGCATCATCA TTGATGGCAT CGACATCGCC AAGCTGCCGC TGCACACGCT CCGTTCACGC 
CTCTCCATCA TCCTACAGGA CCCTGTCCTC TTCAGCGGCA CCATCAGATT CAACCTGGAC 
CCAGAGAAGA AATGCTCAGA CAGCACACTC TGGGAGGCTC TGGAGATCGC CCAGCTGAAG 
CTGGTGGTGA AGGCACTGCC AGGAGGCCTG GATGCCATCA TCACAGAAGG AGGGGAGAAT 
TTTAGTCAAG GTCAGAGGCA GCTGTTCTGC CTGGCTCGGG CCTTCGTGAG AAAGACCAGC 
ATCTTCATCA TGGACGAAGC AACTGCCTCC ATTGACATGG CTACGGAAAA CATCCTCCAG 
AAGGTGGTGA TGACAGCCTT CGCAGACCGC ACTGTGGTCA CCATCGCGCA CCGCGTACAC 
ACCATCCTGA GTGCAGACCT CGTGATGGTC CTGAAGAGGG GAGCCATCCT GGAGTTTGAC 
AAACCGGAGA AGCTTCTGAG CCAGAAGGAC AGCGTCTTCG CCTCCTTCGT CCGCGCGGAC 
AAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Role of osteopontin and its regulation in pancreatic islet.
Biochemical and biophysical research communications495(1)1426-1431(2018 01)
Cai M,Bompada P,Salehi A,Acosta JR,Prasad RB,Atac D,Laakso M,Groop L,De Marinis Y

SUR1-TRPM4 and AQP4 form a heteromultimeric complex that amplifies ion/water osmotic coupling and drives astrocyte swelling.
Glia66(1)108-125(2018 Jan)
Stokum JA,Kwon MS,Woo SK,Tsymbalyuk O,Vennekens R,Gerzanich V,Simard JM

Chronic ?-Cell Depolarization Impairs ?-Cell Identity by Disrupting a Network of Ca
Diabetes66(8)2175-2187(2017 08)
Stancill JS,Cartailler JP,Clayton HW,O'Connor JT,Dickerson MT,Dadi PK,Osipovich AB,Jacobson DA,Magnuson MA

Distinct roles for the mTOR pathway in postnatal morphogenesis, maturation and function of pancreatic islets.
Development (Cambridge, England)144(13)2402-2414(2017 07)
Sinagoga KL,Stone WJ,Schiesser JV,Schweitzer JI,Sampson L,Zheng Y,Wells JM

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ABCC8 cDNA ORF clone, Mus musculus(House mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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