Pdc cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Pdc
Entrez Gene ID	20028
Full Name	phosducin
Synonyms	Rpr-1,Rpr1
General protein information	Preferred Names phosducin Names phosducin 33 kDa phototransducing protein PHD rod photoreceptor 1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 1 Map Location: 1 G1\|1 63.84 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_024458.2	NP_077778.1	phosducin
NM_001159730.1	NP_001153202.1	phosducin

Pathways from BioSystems

Homologies

Xenopus tropicalis (tropical clawed frog)	pdc	XP_002933816.2
Homo sapiens (human)	PDC	NP_002588.3
Canis lupus familiaris (dog)	PDC	NP_001003076.1
Bos taurus (cattle)	PDC	NP_001159999.1
Mus musculus (house mouse)	Pdc	NP_001153202.1
Pan troglodytes (chimpanzee)	PDC	XP_524997.3
Rattus norvegicus (Norway rat)	Pdc	NP_037004.1
Gallus gallus (chicken)	PDC	XP_004943359.1
Danio rerio (zebrafish)	pdcb	NP_001020635.2
	PDC	XP_001107723.2
Danio rerio (zebrafish)	pdca	XP_682823.4

Gene Ontology
Bibliography

Related articles in PubMed

Onecut1 and Onecut2 redundantly regulate early retinal cell fates during development.
Sapkota D, Chintala H, Wu F, Fliesler SJ, Hu Z, Mu X
Proceedings of the National Academy of Sciences of the United States of America111(39)E4086-95(2014 Sep)

Absence of synaptic regulation by phosducin in retinal slices.
Long JH, Arshavsky VY, Burns ME
PloS one8(12)e83970(2013)

Phosphorylation of phosducin accelerates rod recovery from transducin translocation.
Belcastro M, Song H, Sinha S, Song C, Mathers PH, Sokolov M
Investigative ophthalmology & visual science53(6)3084-91(2012 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

the role of phosducin at the rod-to-rod bipolar cell (RBC) synapse
Title: Absence of synaptic regulation by phosducin in retinal slices.

A major regulatory component responsible for setting the sensitivity of signal transmission between photoreceptors and ON-bipolar cells is confined to photoreceptors and that phosducin participates in the underlying molecular mechanism.
Title: Phosducin regulates transmission at the photoreceptor-to-ON-bipolar cell synapse.

Pdc-/- mice displayed exaggerated increases in blood pressure in response to post-operative stress.
Title: Phosducin influences sympathetic activity and prevents stress-induced hypertension in humans and mice.

Dopamine and other light-dependent processes cooperatively regulate the diurnal rhythm of phosducin phosphorylation. Dopamine release in response to light and circadian clocks drives daily rhythms of protein phosphorylation in photoreceptor cells.
Title: Dopamine modulates diurnal and circadian rhythms of protein phosphorylation in photoreceptor cells of mouse retina.

Phosducin does not contribute to adaptation mechanisms of the outer segment by dynamically controlling heterotrimer availability, but is necessary for maintaining normal transducin expression and therefore normal flash sensitivity in rods.
Title: Phosducin regulates the expression of transducin betagamma subunits in rod photoreceptors and does not contribute to phototransduction adaptation.

The following Pdc gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Pdc cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu58413	NM_024458.2 Latest version!	Mus musculus phosducin (Pdc), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
OMu58413	NM_001159730.1 Latest version!	Mus musculus phosducin (Pdc), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Pdc ( NM_024458.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_077778.1 Mus musculus phosducin (Pdc), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu58413
Clone ID Related Accession (Same CDS sequence)	NM_024458.2 , NM_001159730.1
Accession Version	NM_024458.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 735bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-23
Organism	Mus musculus(house mouse)
Product	phosducin
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK020798.1, BC012507.1 and BE950243.1. On Apr 30, 2009 this sequence version replaced NM_024458.1. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC021920.1, AK020798.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAAGAAG CCGCCAGCCA AAGCTTAGAA GAAGATTTTG AAGGACAGGC CACGCACACA 
GGACCCAAAG GAGTAATAAA TGATTGGAGA AAGTTTAAAT TAGAAAGTGA AGATGGTGAT 
TCAATTCCAC CCAGCAAGAA GGAAATCCTC AGACAAATGT CCTCTCCTCA GAGCAGAGAT 
GACTCAAAAG AAAGAATGAG CAGAAAGATG AGCATTCAAG AATATGAACT CATTCATCAA 
GACAAAGAAG ATGAGAGTTG CCTTCGCAAA TACCGGAGGC AGTGCATGCA GGATATGCAT 
CAGAAGTTGA GTTTTGGGCC TAGGTATGGG TTTGTGTATG AGCTGGAAAC AGGGGAGCAA 
TTCCTGGAAA CCATCGAGAA GGAGCAGAAG GTCACCACAA TTGTGGTTAA CATTTACGAG 
GATGGTGTCA GGGGCTGCGA TGCACTCAAC AGCAGCTTAG CGTGCCTTGC AGTAGAGTAC 
CCAATGGTCA AGTTCTGTAA AATAAAAGCT TCTAATACCG GAGCGGGGGA CCGCTTTTCC 
ACAGACGTAC TCCCTACGTT GCTGGTGTAC AAAGGTGGGG AACTCATAAG CAATTTTATT 
AGTGTGGCTG AACAATTTGC TGAAGAATTT TTTGCTGTGG ATGTGGAGTC TTTCCTAAAT 
GAATATGGAT TACTACCAGA AAGAGAGATA CATGACCTAG AGCAGACCAA CATGGAAGAC 
GAGGACATTG AATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_077778.1
CDS	97..831
Translation	MEEAASQSLEEDFEGQATHTGPKGVINDWRKFKLESEDGDSIPPSKKEILRQMSSPQSRDDSKERMSRKMSIQEYELIHQDKEDESCLRKYRRQCMQDMHQKLSFGPRYGFVYELETGEQFLETIEKEQKVTTIVVNIYEDGVRGCDALNSSLACLAVEYPMVKFCKIKASNTGAGDRFSTDVLPTLLVYKGGELISNFISVAEQFAEEFFAVDVESFLNEYGLLPEREIHDLEQTNMEDEDIE

Target ORF information:

RefSeq Version	NM_024458.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus phosducin (Pdc), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_024458.2

ORF Insert Sequence:

ATGGAAGAAG CCGCCAGCCA AAGCTTAGAA GAAGATTTTG AAGGACAGGC CACGCACACA 
GGACCCAAAG GAGTAATAAA TGATTGGAGA AAGTTTAAAT TAGAAAGTGA AGATGGTGAT 
TCAATTCCAC CCAGCAAGAA GGAAATCCTC AGACAAATGT CCTCTCCTCA GAGCAGAGAT 
GACTCAAAAG AAAGAATGAG CAGAAAGATG AGCATTCAAG AATATGAACT CATTCATCAA 
GACAAAGAAG ATGAGAGTTG CCTTCGCAAA TACCGGAGGC AGTGCATGCA GGATATGCAT 
CAGAAGTTGA GTTTTGGGCC TAGGTATGGG TTTGTGTATG AGCTGGAAAC AGGGGAGCAA 
TTCCTGGAAA CCATCGAGAA GGAGCAGAAG GTCACCACAA TTGTGGTTAA CATTTACGAG 
GATGGTGTCA GGGGCTGCGA TGCACTCAAC AGCAGCTTAG CGTGCCTTGC AGTAGAGTAC 
CCAATGGTCA AGTTCTGTAA AATAAAAGCT TCTAATACCG GAGCGGGGGA CCGCTTTTCC 
ACAGACGTAC TCCCTACGTT GCTGGTGTAC AAAGGTGGGG AACTCATAAG CAATTTTATT 
AGTGTGGCTG AACAATTTGC TGAAGAATTT TTTGCTGTGG ATGTGGAGTC TTTCCTAAAT 
GAATATGGAT TACTACCAGA AAGAGAGATA CATGACCTAG AGCAGACCAA CATGGAAGAC 
GAGGACATTG AATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Pdc ( NM_001159730.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001153202.1 Mus musculus phosducin (Pdc), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu58413
Clone ID Related Accession (Same CDS sequence)	NM_024458.2 , NM_001159730.1
Accession Version	NM_001159730.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 735bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-22
Organism	Mus musculus(house mouse)
Product	phosducin
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK020798.1, BI738229.1, BC012507.1 and BE950243.1. Transcript Variant: This variant (1) represents the longer transcript. Both variants encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BI736834.1, BI739848.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAAGAAG CCGCCAGCCA AAGCTTAGAA GAAGATTTTG AAGGACAGGC CACGCACACA 
GGACCCAAAG GAGTAATAAA TGATTGGAGA AAGTTTAAAT TAGAAAGTGA AGATGGTGAT 
TCAATTCCAC CCAGCAAGAA GGAAATCCTC AGACAAATGT CCTCTCCTCA GAGCAGAGAT 
GACTCAAAAG AAAGAATGAG CAGAAAGATG AGCATTCAAG AATATGAACT CATTCATCAA 
GACAAAGAAG ATGAGAGTTG CCTTCGCAAA TACCGGAGGC AGTGCATGCA GGATATGCAT 
CAGAAGTTGA GTTTTGGGCC TAGGTATGGG TTTGTGTATG AGCTGGAAAC AGGGGAGCAA 
TTCCTGGAAA CCATCGAGAA GGAGCAGAAG GTCACCACAA TTGTGGTTAA CATTTACGAG 
GATGGTGTCA GGGGCTGCGA TGCACTCAAC AGCAGCTTAG CGTGCCTTGC AGTAGAGTAC 
CCAATGGTCA AGTTCTGTAA AATAAAAGCT TCTAATACCG GAGCGGGGGA CCGCTTTTCC 
ACAGACGTAC TCCCTACGTT GCTGGTGTAC AAAGGTGGGG AACTCATAAG CAATTTTATT 
AGTGTGGCTG AACAATTTGC TGAAGAATTT TTTGCTGTGG ATGTGGAGTC TTTCCTAAAT 
GAATATGGAT TACTACCAGA AAGAGAGATA CATGACCTAG AGCAGACCAA CATGGAAGAC 
GAGGACATTG AATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001153202.1
CDS	109..843
Translation	MEEAASQSLEEDFEGQATHTGPKGVINDWRKFKLESEDGDSIPPSKKEILRQMSSPQSRDDSKERMSRKMSIQEYELIHQDKEDESCLRKYRRQCMQDMHQKLSFGPRYGFVYELETGEQFLETIEKEQKVTTIVVNIYEDGVRGCDALNSSLACLAVEYPMVKFCKIKASNTGAGDRFSTDVLPTLLVYKGGELISNFISVAEQFAEEFFAVDVESFLNEYGLLPEREIHDLEQTNMEDEDIE

Target ORF information:

RefSeq Version	NM_001159730.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus phosducin (Pdc), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001159730.1

ORF Insert Sequence:

ATGGAAGAAG CCGCCAGCCA AAGCTTAGAA GAAGATTTTG AAGGACAGGC CACGCACACA 
GGACCCAAAG GAGTAATAAA TGATTGGAGA AAGTTTAAAT TAGAAAGTGA AGATGGTGAT 
TCAATTCCAC CCAGCAAGAA GGAAATCCTC AGACAAATGT CCTCTCCTCA GAGCAGAGAT 
GACTCAAAAG AAAGAATGAG CAGAAAGATG AGCATTCAAG AATATGAACT CATTCATCAA 
GACAAAGAAG ATGAGAGTTG CCTTCGCAAA TACCGGAGGC AGTGCATGCA GGATATGCAT 
CAGAAGTTGA GTTTTGGGCC TAGGTATGGG TTTGTGTATG AGCTGGAAAC AGGGGAGCAA 
TTCCTGGAAA CCATCGAGAA GGAGCAGAAG GTCACCACAA TTGTGGTTAA CATTTACGAG 
GATGGTGTCA GGGGCTGCGA TGCACTCAAC AGCAGCTTAG CGTGCCTTGC AGTAGAGTAC 
CCAATGGTCA AGTTCTGTAA AATAAAAGCT TCTAATACCG GAGCGGGGGA CCGCTTTTCC 
ACAGACGTAC TCCCTACGTT GCTGGTGTAC AAAGGTGGGG AACTCATAAG CAATTTTATT 
AGTGTGGCTG AACAATTTGC TGAAGAATTT TTTGCTGTGG ATGTGGAGTC TTTCCTAAAT 
GAATATGGAT TACTACCAGA AAGAGAGATA CATGACCTAG AGCAGACCAA CATGGAAGAC 
GAGGACATTG AATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Onecut1 and Onecut2 redundantly regulate early retinal cell fates during development.
Proceedings of the National Academy of Sciences of the United States of America111(39)E4086-95(2014 Sep)
Sapkota D,Chintala H,Wu F,Fliesler SJ,Hu Z,Mu X

Absence of synaptic regulation by phosducin in retinal slices.
PloS one8(12)e83970(2013)
Long JH,Arshavsky VY,Burns ME

Phosphorylation of phosducin accelerates rod recovery from transducin translocation.
Investigative ophthalmology & visual science53(6)3084-91(2012 May)
Belcastro M,Song H,Sinha S,Song C,Mathers PH,Sokolov M

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Pdc cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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