Lgals3bp cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Lgals3bp
Entrez Gene ID	19039
Full Name	lectin, galactoside-binding, soluble, 3 binding protein
Synonyms	90K,CyCAP,MAC-2BP,Ppicap,Tango10b
General protein information	Preferred Names lectin, galactoside-binding, soluble, 3 binding protein Names galectin-3-binding protein cyp-C-associated protein mama peptidylprolyl isomerase C-associated protein
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 11 Map Location: 11\|11 E2

mRNA and Protein(s)

mRNA	Protein	Name
NM_011150.3	NP_035280.1	galectin-3-binding protein precursor
NM_011150.2	NP_035280.1	galectin-3-binding protein precursor

Pathways from BioSystems

Homologies

Bos taurus (cattle)	LGALS3BP	NP_001039781.1
Mus musculus (house mouse)	Lgals3bp	NP_035280.1
Danio rerio (zebrafish)	zgc:112492	NP_001017658.1
Homo sapiens (human)	LGALS3BP	NP_005558.1
Pan troglodytes (chimpanzee)	LGALS3BP	XP_001158328.1
Danio rerio (zebrafish)	lgals3bpa	NP_001035130.1
Danio rerio (zebrafish)	lgals3bpb	NP_998038.1
Canis lupus familiaris (dog)	CANT1	XP_005624094.1
Rattus norvegicus (Norway rat)	Lgals3bp	NP_620796.1

Gene Ontology
Bibliography

Related articles in PubMed

The role of galectin-3 and galectin-3-binding protein in venous thrombosis.
DeRoo EP, Wrobleski SK, Shea EM, Al-Khalil RK, Hawley AE, Henke PK, Myers DD Jr, Wakefield TW, Diaz JA
Blood125(11)1813-21(2015 Mar)

Lectin galactoside-binding soluble 3 binding protein (LGALS3BP) is a tumor-associated immunomodulatory ligand for CD33-related Siglecs.
L?ubli H, Alisson-Silva F, Stanczak MA, Siddiqui SS, Deng L, Verhagen A, Varki N, Varki A
The Journal of biological chemistry289(48)33481-91(2014 Nov)

Insm1 promotes endocrine cell differentiation by modulating the expression of a network of genes that includes Neurog3 and Ripply3.
Osipovich AB, Long Q, Manduchi E, Gangula R, Hipkens SB, Schneider J, Okubo T, Stoeckert CJ Jr, Takada S, Magnuson MA
Development (Cambridge, England)141(15)2939-49(2014 Aug)

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.
Abonnenc M, Nabeebaccus AA, Mayr U, Barallobre-Barreiro J, Dong X, Cuello F, Sur S, Drozdov I, Langley SR, Lu R, Stathopoulou K, Didangelos A, Yin X, Zimmermann WH, Shah AM, Zampetaki A, Mayr M
Circulation research113(10)1138-47(2013 Oct)

Disruption of sorting nexin 5 causes respiratory failure associated with undifferentiated alveolar epithelial type I cells in mice.
Im SK, Jeong H, Jeong HW, Kim KT, Hwang D, Ikegami M, Kong YY
PloS one8(3)e58511(2013)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Using a mouse stasis model of venous thrombosis, we found that gal3bp and gal3 were localized on vein wall, red blood cells, platelets, and microparticles, whereas leukocytes expressed gal3 only.
Title: The role of galectin-3 and galectin-3-binding protein in venous thrombosis.

These findings suggest a novel immunoinhibitory function for LGALS3BP that might be important for immune evasion of tumor cells during cancer progression.
Title: Lectin galactoside-binding soluble 3 binding protein (LGALS3BP) is a tumor-associated immunomodulatory ligand for CD33-related Siglecs.

Data give novel evidence that CyCAP regulates the post-translational modification of tissue transglutaminase through its colocalization with calnexin in endoplasmic reticulum.
Title: Cyclophilin C-associated protein/Mac-2 binding protein colocalizes with calnexin and regulates the expression of tissue transglutaminase.

CyCAP-deficient mice spontaneously and after challenge with carcinogen develop significantly more colorectal mucosal hyperplasia, an early stage in murine colonic carcinogenesis
Title: Cyclophilin C-associated protein (CyCAP) knock-out mice spontaneously develop colonic mucosal hyperplasia and exaggerated tumorigenesis after treatment with carcinogen azoxymethane.

Cyclophilin C-associated protein is expressed in skin and during wound repair. It is regulated by IFNgamma and may function on immune defense in macrophages, lymphocytes, dermal fibroblasts and keratinocytes during wound healing.
Title: Cyclophilin C-associated protein is up-regulated during wound healing.

The following Lgals3bp gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Lgals3bp cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu07558	NM_011150.3 Latest version!	Mus musculus lectin, galactoside-binding, soluble, 3 binding protein (Lgals3bp), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$335.30 $479.00
View Old Accession Versions >>
OMu07558	NM_011150.2	Mus musculus lectin, galactoside-binding, soluble, 3 binding protein (Lgals3bp), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$335.30 $479.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Lgals3bp ( NM_011150.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_035280.1 Mus musculus lectin, galactoside-binding, soluble, 3 binding protein (Lgals3bp), mRNA.

Price & Availability↑

CloneID	OMu07558
Clone ID Related Accession (Same CDS sequence)	NM_011150.3 , NM_011150.2
Accession Version	NM_011150.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1734bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-05
Organism	Mus musculus(house mouse)
Product	galectin-3-binding protein precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK079915.1 and BP765555.1. On Feb 22, 2018 this sequence version replaced NM_011150.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK079915.1, AK150021.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTCTCC TGTGGCTCCT CTCTGTGTTC TTGCTGGTTC CAGGGACTCA AGGTACAGAA 
GATGGAGACA TGCGCTTGGT TAACGGGGCC TCAGCCAATG AGGGCCGCGT GGAGATCTTC 
TACAGAGGCC GGTGGGGGAC AGTGTGTGAC AACCTCTGGA ACCTTTTGGA TGCCCACGTC 
GTCTGCCGGG CCCTGGGCTA TGAGAACGCC ACCCAAGCAC TGGGCAGAGC TGCCTTCGGG 
CCAGGAAAGG GACCGATCAT GCTGGATGAG GTGGAATGTA CAGGGACCGA GTCCTCACTG 
GCCAGTTGCA GATCCCTGGG TTGGATGGTG AGCCGCTGTG GGCACGAGAA GGACGCAGGC 
GTGGTCTGCT CCAACGATAC CACGGGGCTT CACATCCTGG ACCTCTCTGG AGAGCTCTCA 
GATGCACTGG GCCAGATCTT TGACAGCCAG CAGGGCTGCG ACCTATTCAT CCAGGTGACA 
GGGCAGGGGT ATGAGGACCT GAGCCTCTGT GCCCACACGC TGATCCTGCG CACCAACCCC 
GAGGCCCAGG CCCTGTGGCA AGTGGTGGGC AGCAGCGTCA TCATGAGAGT GGATGCTGAG 
TGCATGCCTG TCGTCAGAGA CTTCCTCAGG TACTTTTACT CCCGAAGAAT CGAGGTCAGC 
ATGTCTTCTG TTAAGTGCTT GCACAAGCTA GCCTCTGCCT ATGGGGCCAC AGAGCTTCAG 
GACTACTGTG GACGGCTTTT TGCCACCCTC CTCCCCCAAG ACCCCACTTT CCATACTCCC 
TTGGACCTTT ATGCGTACGC ACGGGCCACC GGGGACTCTA TGCTGGAAGA TCTGTGTGTA 
CAGTTTCTGG CCTGGAACTT CGAGCCTCTG ACACAGTCTG AGTCCTGGTC GGCTGTTCCC 
ACCACCTTGA TCCAGGCTCT CCTCCCCAAG AGTGAGCTGG CTGTGTCTAG TGAGCTGGAT 
CTGCTGAAGG CAGTGGACCA GTGGAGCACA GAAACCATTG CCTCACACGA GGATATAGAG 
CGCCTGGTGG AACAGGTCCG CTTCCCCATG ATGCTGCCCC AGGAGCTGTT CGAGCTGCAG 
TTCAACCTGT CCTTGTACCA AGATCACCAG GCACTGTTCC AGAGGAAGAC CATGCAGGCC 
TTGGAGTTCC ACACAGTGCC TGTCGAAGTG CTGGCCAAGT ACAAAGGCCT GAACCTCACG 
GAGGACACCT ACAAGCCCCG CCTTTACACC TCTTCCACCT GGAGTAGCTT GGTGATGGCC 
TCCACCTGGA GGGCACAAAG ATATGAATAC AATCGATACA ATCAGCTCTA TACATATGGC 
TATGGCTCAG TAGCCCGGTA CAATAGCTAC CAGTCCTTCC AAACCCCACA ACACCCCAGC 
TTCCTCTTCA AGGACAAGCA GATCTCCTGG TCAGCCACCT ACCTCCCCAC CATGCAGAGC 
TGCTGGAACT ATGGCTTCTC GTGTACCTCT AACGAGCTCC CTGTACTGGG CCTCACCACA 
TCCAGCTACT CCAATCCGAC AATTGGCTAT GAGAACAGAG TACTGATCCT CTGCGGAGGC 
TACAGTGTGG TGGATGTCAC CAGCTTTGAA GGCTCCAAGG CCCCTATTCC CACTGCCCTG 
GACACCAATA GTTCCAAGAC TCCCTCCCTC TTTCCCTGTG CCTCAGGGGC CTTTAGCAGC 
TTCCGTGTGG TCATACGCCC CTTCTACCTC ACTAACTCCA CTGACATGGT GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_035280.1
CDS	197..1930
Translation	MALLWLLSVFLLVPGTQGTEDGDMRLVNGASANEGRVEIFYRGRWGTVCDNLWNLLDAHVVCRALGYENATQALGRAAFGPGKGPIMLDEVECTGTESSLASCRSLGWMVSRCGHEKDAGVVCSNDTTGLHILDLSGELSDALGQIFDSQQGCDLFIQVTGQGYEDLSLCAHTLILRTNPEAQALWQVVGSSVIMRVDAECMPVVRDFLRYFYSRRIEVSMSSVKCLHKLASAYGATELQDYCGRLFATLLPQDPTFHTPLDLYAYARATGDSMLEDLCVQFLAWNFEPLTQSESWSAVPTTLIQALLPKSELAVSSELDLLKAVDQWSTETIASHEDIERLVEQVRFPMMLPQELFELQFNLSLYQDHQALFQRKTMQALEFHTVPVEVLAKYKGLNLTEDTYKPRLYTSSTWSSLVMASTWRAQRYEYNRYNQLYTYGYGSVARYNSYQSFQTPQHPSFLFKDKQISWSATYLPTMQSCWNYGFSCTSNELPVLGLTTSSYSNPTIGYENRVLILCGGYSVVDVTSFEGSKAPIPTALDTNSSKTPSLFPCASGAFSSFRVVIRPFYLTNSTDMV

Target ORF information:

RefSeq Version	NM_011150.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus lectin, galactoside-binding, soluble, 3 binding protein (Lgals3bp), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_011150.3

ORF Insert Sequence:

ATGGCTCTCC TGTGGCTCCT CTCTGTGTTC TTGCTGGTTC CAGGGACTCA AGGTACAGAA 
GATGGAGACA TGCGCTTGGT TAACGGGGCC TCAGCCAATG AGGGCCGCGT GGAGATCTTC 
TACAGAGGCC GGTGGGGGAC AGTGTGTGAC AACCTCTGGA ACCTTTTGGA TGCCCACGTC 
GTCTGCCGGG CCCTGGGCTA TGAGAACGCC ACCCAAGCAC TGGGCAGAGC TGCCTTCGGG 
CCAGGAAAGG GACCGATCAT GCTGGATGAG GTGGAATGTA CAGGGACCGA GTCCTCACTG 
GCCAGTTGCA GATCCCTGGG TTGGATGGTG AGCCGCTGTG GGCACGAGAA GGACGCAGGC 
GTGGTCTGCT CCAACGATAC CACGGGGCTT CACATCCTGG ACCTCTCTGG AGAGCTCTCA 
GATGCACTGG GCCAGATCTT TGACAGCCAG CAGGGCTGCG ACCTATTCAT CCAGGTGACA 
GGGCAGGGGT ATGAGGACCT GAGCCTCTGT GCCCACACGC TGATCCTGCG CACCAACCCC 
GAGGCCCAGG CCCTGTGGCA AGTGGTGGGC AGCAGCGTCA TCATGAGAGT GGATGCTGAG 
TGCATGCCTG TCGTCAGAGA CTTCCTCAGG TACTTTTACT CCCGAAGAAT CGAGGTCAGC 
ATGTCTTCTG TTAAGTGCTT GCACAAGCTA GCCTCTGCCT ATGGGGCCAC AGAGCTTCAG 
GACTACTGTG GACGGCTTTT TGCCACCCTC CTCCCCCAAG ACCCCACTTT CCATACTCCC 
TTGGACCTTT ATGCGTACGC ACGGGCCACC GGGGACTCTA TGCTGGAAGA TCTGTGTGTA 
CAGTTTCTGG CCTGGAACTT CGAGCCTCTG ACACAGTCTG AGTCCTGGTC GGCTGTTCCC 
ACCACCTTGA TCCAGGCTCT CCTCCCCAAG AGTGAGCTGG CTGTGTCTAG TGAGCTGGAT 
CTGCTGAAGG CAGTGGACCA GTGGAGCACA GAAACCATTG CCTCACACGA GGATATAGAG 
CGCCTGGTGG AACAGGTCCG CTTCCCCATG ATGCTGCCCC AGGAGCTGTT CGAGCTGCAG 
TTCAACCTGT CCTTGTACCA AGATCACCAG GCACTGTTCC AGAGGAAGAC CATGCAGGCC 
TTGGAGTTCC ACACAGTGCC TGTCGAAGTG CTGGCCAAGT ACAAAGGCCT GAACCTCACG 
GAGGACACCT ACAAGCCCCG CCTTTACACC TCTTCCACCT GGAGTAGCTT GGTGATGGCC 
TCCACCTGGA GGGCACAAAG ATATGAATAC AATCGATACA ATCAGCTCTA TACATATGGC 
TATGGCTCAG TAGCCCGGTA CAATAGCTAC CAGTCCTTCC AAACCCCACA ACACCCCAGC 
TTCCTCTTCA AGGACAAGCA GATCTCCTGG TCAGCCACCT ACCTCCCCAC CATGCAGAGC 
TGCTGGAACT ATGGCTTCTC GTGTACCTCT AACGAGCTCC CTGTACTGGG CCTCACCACA 
TCCAGCTACT CCAATCCGAC AATTGGCTAT GAGAACAGAG TACTGATCCT CTGCGGAGGC 
TACAGTGTGG TGGATGTCAC CAGCTTTGAA GGCTCCAAGG CCCCTATTCC CACTGCCCTG 
GACACCAATA GTTCCAAGAC TCCCTCCCTC TTTCCCTGTG CCTCAGGGGC CTTTAGCAGC 
TTCCGTGTGG TCATACGCCC CTTCTACCTC ACTAACTCCA CTGACATGGT GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Lgals3bp ( NM_011150.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_035280.1 Mus musculus lectin, galactoside-binding, soluble, 3 binding protein (Lgals3bp), mRNA.

Price & Availability↑

CloneID	OMu07558
Clone ID Related Accession (Same CDS sequence)	NM_011150.3 , NM_011150.2
Accession Version	NM_011150.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1734bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-27
Organism	Mus musculus(house mouse)
Product	galectin-3-binding protein precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AL591404.4. On Nov 17, 2006 this sequence version replaced NM_011150.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: X67809.1, AK150021.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGGCTCTCC TGTGGCTCCT CTCTGTGTTC TTGCTGGTTC CAGGGACTCA AGGTACAGAA 
GATGGAGACA TGCGCTTGGT TAACGGGGCC TCAGCCAATG AGGGCCGCGT GGAGATCTTC 
TACAGAGGCC GGTGGGGGAC AGTGTGTGAC AACCTCTGGA ACCTTTTGGA TGCCCACGTC 
GTCTGCCGGG CCCTGGGCTA TGAGAACGCC ACCCAAGCAC TGGGCAGAGC TGCCTTCGGG 
CCAGGAAAGG GACCGATCAT GCTGGATGAG GTGGAATGTA CAGGGACCGA GTCCTCACTG 
GCCAGTTGCA GATCCCTGGG TTGGATGGTG AGCCGCTGTG GGCACGAGAA GGACGCAGGC 
GTGGTCTGCT CCAACGATAC CACGGGGCTT CACATCCTGG ACCTCTCTGG AGAGCTCTCA 
GATGCACTGG GCCAGATCTT TGACAGCCAG CAGGGCTGCG ACCTATTCAT CCAGGTGACA 
GGGCAGGGGT ATGAGGACCT GAGCCTCTGT GCCCACACGC TGATCCTGCG CACCAACCCC 
GAGGCCCAGG CCCTGTGGCA AGTGGTGGGC AGCAGCGTCA TCATGAGAGT GGATGCTGAG 
TGCATGCCTG TCGTCAGAGA CTTCCTCAGG TACTTTTACT CCCGAAGAAT CGAGGTCAGC 
ATGTCTTCTG TTAAGTGCTT GCACAAGCTA GCCTCTGCCT ATGGGGCCAC AGAGCTTCAG 
GACTACTGTG GACGGCTTTT TGCCACCCTC CTCCCCCAAG ACCCCACTTT CCATACTCCC 
TTGGACCTTT ATGCGTACGC ACGGGCCACC GGGGACTCTA TGCTGGAAGA TCTGTGTGTA 
CAGTTTCTGG CCTGGAACTT CGAGCCTCTG ACACAGTCTG AGTCCTGGTC GGCTGTTCCC 
ACCACCTTGA TCCAGGCTCT CCTCCCCAAG AGTGAGCTGG CTGTGTCTAG TGAGCTGGAT 
CTGCTGAAGG CAGTGGACCA GTGGAGCACA GAAACCATTG CCTCACACGA GGATATAGAG 
CGCCTGGTGG AACAGGTCCG CTTCCCCATG ATGCTGCCCC AGGAGCTGTT CGAGCTGCAG 
TTCAACCTGT CCTTGTACCA AGATCACCAG GCACTGTTCC AGAGGAAGAC CATGCAGGCC 
TTGGAGTTCC ACACAGTGCC TGTCGAAGTG CTGGCCAAGT ACAAAGGCCT GAACCTCACG 
GAGGACACCT ACAAGCCCCG CCTTTACACC TCTTCCACCT GGAGTAGCTT GGTGATGGCC 
TCCACCTGGA GGGCACAAAG ATATGAATAC AATCGATACA ATCAGCTCTA TACATATGGC 
TATGGCTCAG TAGCCCGGTA CAATAGCTAC CAGTCCTTCC AAACCCCACA ACACCCCAGC 
TTCCTCTTCA AGGACAAGCA GATCTCCTGG TCAGCCACCT ACCTCCCCAC CATGCAGAGC 
TGCTGGAACT ATGGCTTCTC GTGTACCTCT AACGAGCTCC CTGTACTGGG CCTCACCACA 
TCCAGCTACT CCAATCCGAC AATTGGCTAT GAGAACAGAG TACTGATCCT CTGCGGAGGC 
TACAGTGTGG TGGATGTCAC CAGCTTTGAA GGCTCCAAGG CCCCTATTCC CACTGCCCTG 
GACACCAATA GTTCCAAGAC TCCCTCCCTC TTTCCCTGTG CCTCAGGGGC CTTTAGCAGC 
TTCCGTGTGG TCATACGCCC CTTCTACCTC ACTAACTCCA CTGACATGGT GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_035280.1
CDS	169..1902
Translation	MALLWLLSVFLLVPGTQGTEDGDMRLVNGASANEGRVEIFYRGRWGTVCDNLWNLLDAHVVCRALGYENATQALGRAAFGPGKGPIMLDEVECTGTESSLASCRSLGWMVSRCGHEKDAGVVCSNDTTGLHILDLSGELSDALGQIFDSQQGCDLFIQVTGQGYEDLSLCAHTLILRTNPEAQALWQVVGSSVIMRVDAECMPVVRDFLRYFYSRRIEVSMSSVKCLHKLASAYGATELQDYCGRLFATLLPQDPTFHTPLDLYAYARATGDSMLEDLCVQFLAWNFEPLTQSESWSAVPTTLIQALLPKSELAVSSELDLLKAVDQWSTETIASHEDIERLVEQVRFPMMLPQELFELQFNLSLYQDHQALFQRKTMQALEFHTVPVEVLAKYKGLNLTEDTYKPRLYTSSTWSSLVMASTWRAQRYEYNRYNQLYTYGYGSVARYNSYQSFQTPQHPSFLFKDKQISWSATYLPTMQSCWNYGFSCTSNELPVLGLTTSSYSNPTIGYENRVLILCGGYSVVDVTSFEGSKAPIPTALDTNSSKTPSLFPCASGAFSSFRVVIRPFYLTNSTDMV

Target ORF information:

RefSeq Version	NM_011150.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus lectin, galactoside-binding, soluble, 3 binding protein (Lgals3bp), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_011150.2

ORF Insert Sequence:

ATGGCTCTCC TGTGGCTCCT CTCTGTGTTC TTGCTGGTTC CAGGGACTCA AGGTACAGAA 
GATGGAGACA TGCGCTTGGT TAACGGGGCC TCAGCCAATG AGGGCCGCGT GGAGATCTTC 
TACAGAGGCC GGTGGGGGAC AGTGTGTGAC AACCTCTGGA ACCTTTTGGA TGCCCACGTC 
GTCTGCCGGG CCCTGGGCTA TGAGAACGCC ACCCAAGCAC TGGGCAGAGC TGCCTTCGGG 
CCAGGAAAGG GACCGATCAT GCTGGATGAG GTGGAATGTA CAGGGACCGA GTCCTCACTG 
GCCAGTTGCA GATCCCTGGG TTGGATGGTG AGCCGCTGTG GGCACGAGAA GGACGCAGGC 
GTGGTCTGCT CCAACGATAC CACGGGGCTT CACATCCTGG ACCTCTCTGG AGAGCTCTCA 
GATGCACTGG GCCAGATCTT TGACAGCCAG CAGGGCTGCG ACCTATTCAT CCAGGTGACA 
GGGCAGGGGT ATGAGGACCT GAGCCTCTGT GCCCACACGC TGATCCTGCG CACCAACCCC 
GAGGCCCAGG CCCTGTGGCA AGTGGTGGGC AGCAGCGTCA TCATGAGAGT GGATGCTGAG 
TGCATGCCTG TCGTCAGAGA CTTCCTCAGG TACTTTTACT CCCGAAGAAT CGAGGTCAGC 
ATGTCTTCTG TTAAGTGCTT GCACAAGCTA GCCTCTGCCT ATGGGGCCAC AGAGCTTCAG 
GACTACTGTG GACGGCTTTT TGCCACCCTC CTCCCCCAAG ACCCCACTTT CCATACTCCC 
TTGGACCTTT ATGCGTACGC ACGGGCCACC GGGGACTCTA TGCTGGAAGA TCTGTGTGTA 
CAGTTTCTGG CCTGGAACTT CGAGCCTCTG ACACAGTCTG AGTCCTGGTC GGCTGTTCCC 
ACCACCTTGA TCCAGGCTCT CCTCCCCAAG AGTGAGCTGG CTGTGTCTAG TGAGCTGGAT 
CTGCTGAAGG CAGTGGACCA GTGGAGCACA GAAACCATTG CCTCACACGA GGATATAGAG 
CGCCTGGTGG AACAGGTCCG CTTCCCCATG ATGCTGCCCC AGGAGCTGTT CGAGCTGCAG 
TTCAACCTGT CCTTGTACCA AGATCACCAG GCACTGTTCC AGAGGAAGAC CATGCAGGCC 
TTGGAGTTCC ACACAGTGCC TGTCGAAGTG CTGGCCAAGT ACAAAGGCCT GAACCTCACG 
GAGGACACCT ACAAGCCCCG CCTTTACACC TCTTCCACCT GGAGTAGCTT GGTGATGGCC 
TCCACCTGGA GGGCACAAAG ATATGAATAC AATCGATACA ATCAGCTCTA TACATATGGC 
TATGGCTCAG TAGCCCGGTA CAATAGCTAC CAGTCCTTCC AAACCCCACA ACACCCCAGC 
TTCCTCTTCA AGGACAAGCA GATCTCCTGG TCAGCCACCT ACCTCCCCAC CATGCAGAGC 
TGCTGGAACT ATGGCTTCTC GTGTACCTCT AACGAGCTCC CTGTACTGGG CCTCACCACA 
TCCAGCTACT CCAATCCGAC AATTGGCTAT GAGAACAGAG TACTGATCCT CTGCGGAGGC 
TACAGTGTGG TGGATGTCAC CAGCTTTGAA GGCTCCAAGG CCCCTATTCC CACTGCCCTG 
GACACCAATA GTTCCAAGAC TCCCTCCCTC TTTCCCTGTG CCTCAGGGGC CTTTAGCAGC 
TTCCGTGTGG TCATACGCCC CTTCTACCTC ACTAACTCCA CTGACATGGT GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The role of galectin-3 and galectin-3-binding protein in venous thrombosis.
Blood125(11)1813-21(2015 Mar)
DeRoo EP,Wrobleski SK,Shea EM,Al-Khalil RK,Hawley AE,Henke PK,Myers DD Jr,Wakefield TW,Diaz JA

Lectin galactoside-binding soluble 3 binding protein (LGALS3BP) is a tumor-associated immunomodulatory ligand for CD33-related Siglecs.
The Journal of biological chemistry289(48)33481-91(2014 Nov)
L?ubli H,Alisson-Silva F,Stanczak MA,Siddiqui SS,Deng L,Verhagen A,Varki N,Varki A

Insm1 promotes endocrine cell differentiation by modulating the expression of a network of genes that includes Neurog3 and Ripply3.
Development (Cambridge, England)141(15)2939-49(2014 Aug)
Osipovich AB,Long Q,Manduchi E,Gangula R,Hipkens SB,Schneider J,Okubo T,Stoeckert CJ Jr,Takada S,Magnuson MA

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.
Circulation research113(10)1138-47(2013 Oct)
Abonnenc M,Nabeebaccus AA,Mayr U,Barallobre-Barreiro J,Dong X,Cuello F,Sur S,Drozdov I,Langley SR,Lu R,Stathopoulou K,Didangelos A,Yin X,Zimmermann WH,Shah AM,Zampetaki A,Mayr M

Disruption of sorting nexin 5 causes respiratory failure associated with undifferentiated alveolar epithelial type I cells in mice.
PloS one8(3)e58511(2013)
Im SK,Jeong H,Jeong HW,Kim KT,Hwang D,Ikegami M,Kong YY

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Lgals3bp cDNA ORF clone, Mus musculus(house mouse)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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