P2rx6 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	P2rx6
Entrez Gene ID	18440
Full Name	purinergic receptor P2X, ligand-gated ion channel, 6
Synonyms	P2rxl1,P2x6,P2xm
General protein information	Preferred Names purinergic receptor P2X, ligand-gated ion channel, 6 Names P2X purinoceptor 6 ATP receptor purinergic receptor P2X-like 1, orphan receptor
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 16 Map Location: 16\|16 A3

mRNA and Protein(s)

mRNA	Protein	Name
XM_006521856.2	XP_006521919.1	P2X purinoceptor 6 isoform X1
NM_011028.2	NP_035158.2	P2X purinoceptor 6 isoform 1
NM_001159561.1	NP_001153033.1	P2X purinoceptor 6 isoform 2

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	P2rx6	NP_035158.2
Gallus gallus (chicken)	LOC429367	XP_426924.4
Homo sapiens (human)	P2RX6	NP_005437.2
	P2RX6	XP_001084368.1
Bos taurus (cattle)	P2RX6	XP_005218354.1
Rattus norvegicus (Norway rat)	P2rx6	NP_036853.2
Canis lupus familiaris (dog)	P2RX6	XP_005636671.1

Gene Ontology
Bibliography

Related articles in PubMed

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)

P2X6 Knockout Mice Exhibit Normal Electrolyte Homeostasis.
de Baaij JH, Kompatscher A, Viering DH, Bos C, Bindels RJ, Hoenderop JG
PloS one11(6)e0156803(2016)

Mouse and human CRKL is dosage sensitive for cardiac outflow tract formation.
Racedo SE, McDonald-McGinn DM, Chung JH, Goldmuntz E, Zackai E, Emanuel BS, Zhou B, Funke B, Morrow BE
American journal of human genetics96(2)235-44(2015 Feb)

Age-related nuclear translocation of P2X6 subunit modifies splicing activity interacting with splicing factor 3A1.
D?az-Hern?ndez JI, Sebasti?n-Serrano ?, G?mez-Villafuertes R, D?az-Hern?ndez M, Miras-Portugal MT
PloS one10(4)e0123121(2015)

P2X receptors are expressed on neurons containing luteinizing hormone-releasing hormone in the mouse hypothalamus.
Fu J, Yu Q, Guo W, He C, Burnstock G, Xiang Z
Neuroscience letters458(1)32-6(2009 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

purinergic signaling via P2X6 is not significantly involved in the regulation of renal electrolyte handling under normal physiological conditions.
Title: P2X6 Knockout Mice Exhibit Normal Electrolyte Homeostasis.

once inside the nucleus, P2X6 subunit interacts with the splicing factor 3A1, which ultimately results in a reduction of the mRNA splicing activity
Title: Age-related nuclear translocation of P2X6 subunit modifies splicing activity interacting with splicing factor 3A1.

This study provides the first evidence that P2X8 receptors are expressed on LHRH-containing neurons.
Title: P2X receptors are expressed on neurons containing luteinizing hormone-releasing hormone in the mouse hypothalamus.

Immunoreactivity for P2X3-, P2X5-, and P2X6-purinoceptors was observed in mouse retina.
Title: Distribution of immunoreactivity for P2X3, P2X5, and P2X6-purinoceptors in mouse retina.

The following P2rx6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the P2rx6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu07328	NM_011028.2 Latest version!	Mus musculus purinergic receptor P2X, ligand-gated ion channel, 6 (P2rx6), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00
OMu07564	NM_001159561.1 Latest version!	Mus musculus purinergic receptor P2X, ligand-gated ion channel, 6 (P2rx6), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00
OMu51925	XM_006521856.2 Latest version!	Mus musculus purinergic receptor P2X, ligand-gated ion channel, 6 (P2rx6), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

P2rx6 ( NM_011028.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_035158.2 Mus musculus purinergic receptor P2X, ligand-gated ion channel, 6 (P2rx6), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu07328
Clone ID Related Accession (Same CDS sequence)	NM_011028.2
Accession Version	NM_011028.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1170bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Mus musculus(house mouse)
Product	P2X purinoceptor 6 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY303078.1, AK138541.1 and AW490413.1. On Apr 21, 2009 this sequence version replaced NM_011028.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). ##Evidence-Data-START## Transcript exon combination :: AK081308.1, AK138541.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCAGTTGC AGCCAGCAGG AACTGGGAAC ATGGCTTCTG CAGCCGCAGC AGCACTCGTG 
AGCTGGGGGT TTCTGGATTA CAAGACGGAG AAATATGTGC TAACCAGGAA CTGTCGGGTG 
GGCGTCTCCC AGAGGCTGCT GCAGCTGGCA GTGGTAGTCT ACGTGATAGG GTGGGCCCTC 
TTGGCCAAAA AAGGCTACCA GGAACGGGAC TTGGCCCCTC AGACTTCTGT CATCACCAAA 
CTCAAGGGGG TTTCTGTAAC CCAGGTTAAG GAGCTGGAGA ACCGGCTGTG GGACGTGGCT 
GACTTTGTGA AGCCATCACA GGGAGAGAAC GTGTTCTTCC TGGTAACCAA CTTCCTCGTG 
ACACCAGCTC AAGTCCAGGG CAGATGTCCA GAGCATCCTT CCGTTCCTCT GGCTAACTGC 
TGGGCTGATG AAGACTGCCC CGAAGGGGAG ACGGGGACAT ACAGCCATGG CATAAAAACT 
GGTCAGTGTG TGGTGTTCAA CGGAACCCAC AGGACCTGTG AGATCTGGAG CTGGTGCCCA 
GTGGAGAGTG GTGCTGTGCC CAGGAAGCCC CTGCTAGCTC AGGCCAAGAA CTTCACACTC 
TTCATCAAAA ATACTGTAAC CTTCAGCAAG TTCAACTTCT CCAGATCCAA TGCCTTATTA 
ACCTGGGACA ACACATATTT CAAGCATTGT CTCTATGATC CACTCTCCAG TCCGTACTGC 
CCAGTGTTCC GCATCGGGGA CCTTGTGGCC ATGGCTGGAG GGGACTTTGA GGACCTGGCC 
TTGCTGGGTG GTGCTGTGGG CATCAGCATT CACTGGGATT GCAACCTGGA CACGAAAGGC 
TCTGACTGCT GTCCCCAGTA CTCCTTCCAG CTGCAGCAGA AAGGGTACAA CTTCAGGACA 
GCCAATCACT GGTGGGCAGC CTCAGGCGTG GAGACCCGGA GCCTGCTCAA GCTCTATGGA 
ATCCGTTTTG ACATTCTTGT CACTGGGCAG GCAGGGAAGT TCGCGCTCAT CCCTACGGCC 
ATCACAGTGG GCACAGGAGC GGCTTGGCTG GGCATGGTCA CCTTCCTCTG TGACCTGCTG 
CTACTGTATG TGGATAGAGA GGCCGGTTTC TACTGGAGAA CCAAATATGA AGAGGCAAGA 
GCCCCAAAGA CGACTACCAA CAGTTCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_035158.2
CDS	130..1299
Translation	MQLQPAGTGNMASAAAAALVSWGFLDYKTEKYVLTRNCRVGVSQRLLQLAVVVYVIGWALLAKKGYQERDLAPQTSVITKLKGVSVTQVKELENRLWDVADFVKPSQGENVFFLVTNFLVTPAQVQGRCPEHPSVPLANCWADEDCPEGETGTYSHGIKTGQCVVFNGTHRTCEIWSWCPVESGAVPRKPLLAQAKNFTLFIKNTVTFSKFNFSRSNALLTWDNTYFKHCLYDPLSSPYCPVFRIGDLVAMAGGDFEDLALLGGAVGISIHWDCNLDTKGSDCCPQYSFQLQQKGYNFRTANHWWAASGVETRSLLKLYGIRFDILVTGQAGKFALIPTAITVGTGAAWLGMVTFLCDLLLLYVDREAGFYWRTKYEEARAPKTTTNSS

Target ORF information:

RefSeq Version	NM_011028.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus purinergic receptor P2X, ligand-gated ion channel, 6 (P2rx6), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_011028.2

ORF Insert Sequence:

ATGCAGTTGC AGCCAGCAGG AACTGGGAAC ATGGCTTCTG CAGCCGCAGC AGCACTCGTG 
AGCTGGGGGT TTCTGGATTA CAAGACGGAG AAATATGTGC TAACCAGGAA CTGTCGGGTG 
GGCGTCTCCC AGAGGCTGCT GCAGCTGGCA GTGGTAGTCT ACGTGATAGG GTGGGCCCTC 
TTGGCCAAAA AAGGCTACCA GGAACGGGAC TTGGCCCCTC AGACTTCTGT CATCACCAAA 
CTCAAGGGGG TTTCTGTAAC CCAGGTTAAG GAGCTGGAGA ACCGGCTGTG GGACGTGGCT 
GACTTTGTGA AGCCATCACA GGGAGAGAAC GTGTTCTTCC TGGTAACCAA CTTCCTCGTG 
ACACCAGCTC AAGTCCAGGG CAGATGTCCA GAGCATCCTT CCGTTCCTCT GGCTAACTGC 
TGGGCTGATG AAGACTGCCC CGAAGGGGAG ACGGGGACAT ACAGCCATGG CATAAAAACT 
GGTCAGTGTG TGGTGTTCAA CGGAACCCAC AGGACCTGTG AGATCTGGAG CTGGTGCCCA 
GTGGAGAGTG GTGCTGTGCC CAGGAAGCCC CTGCTAGCTC AGGCCAAGAA CTTCACACTC 
TTCATCAAAA ATACTGTAAC CTTCAGCAAG TTCAACTTCT CCAGATCCAA TGCCTTATTA 
ACCTGGGACA ACACATATTT CAAGCATTGT CTCTATGATC CACTCTCCAG TCCGTACTGC 
CCAGTGTTCC GCATCGGGGA CCTTGTGGCC ATGGCTGGAG GGGACTTTGA GGACCTGGCC 
TTGCTGGGTG GTGCTGTGGG CATCAGCATT CACTGGGATT GCAACCTGGA CACGAAAGGC 
TCTGACTGCT GTCCCCAGTA CTCCTTCCAG CTGCAGCAGA AAGGGTACAA CTTCAGGACA 
GCCAATCACT GGTGGGCAGC CTCAGGCGTG GAGACCCGGA GCCTGCTCAA GCTCTATGGA 
ATCCGTTTTG ACATTCTTGT CACTGGGCAG GCAGGGAAGT TCGCGCTCAT CCCTACGGCC 
ATCACAGTGG GCACAGGAGC GGCTTGGCTG GGCATGGTCA CCTTCCTCTG TGACCTGCTG 
CTACTGTATG TGGATAGAGA GGCCGGTTTC TACTGGAGAA CCAAATATGA AGAGGCAAGA 
GCCCCAAAGA CGACTACCAA CAGTTCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

P2rx6 ( NM_001159561.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001153033.1 Mus musculus purinergic receptor P2X, ligand-gated ion channel, 6 (P2rx6), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu07564
Clone ID Related Accession (Same CDS sequence)	NM_001159561.1
Accession Version	NM_001159561.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1089bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-20
Organism	Mus musculus(house mouse)
Product	P2X purinoceptor 6 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY303078.1, BC117713.2, AK138541.1 and AW490413.1. Transcript Variant: This variant (2) lacks an alternate in-frame exon in the central coding region, compared to variant 1, resulting in an isoform (2) that is shorter than isoform 1. ##Evidence-Data-START## Transcript exon combination :: BC117713.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCAGTTGC AGCCAGCAGG AACTGGGAAC ATGGCTTCTG CAGCCGCAGC AGCACTCGTG 
AGCTGGGGGT TTCTGGATTA CAAGACGGAG AAATATGTGC TAACCAGGAA CTGTCGGGTG 
GGCGTCTCCC AGAGGCTGCT GCAGCTGGCA GTGGTAGTCT ACGTGATAGG GTGGGCCCTC 
TTGGCCAAAA AAGGCTACCA GGAACGGGAC TTGGCCCCTC AGACTTCTGT CATCACCAAA 
CTCAAGGGGG TTTCTGTAAC CCAGGTTAAG GAGCTGGAGA ACCGGCTGTG GGACGTGGCT 
GACTTTGTGA AGCCATCACA GGGAGAGAAC GTGTTCTTCC TGGTAACCAA CTTCCTCGTG 
ACACCAGCTC AAGTCCAGGG CAGATGTCCA GAGCATCCTT CCGTTCCTCT GGCTAACTGC 
TGGGCTGATG AAGACTGCCC CGAAGGGGAG ACGGGGACAT ACAGCCATGG CATAAAAACT 
GGTCAGTGTG TGGTGTTCAA CGGAACCCAC AGGACCTGTG AGATCTGGAG CTGGTGCCCA 
GTGGAGAGTG GTGCTGTGCC CAGATCCAAT GCCTTATTAA CCTGGGACAA CACATATTTC 
AAGCATTGTC TCTATGATCC ACTCTCCAGT CCGTACTGCC CAGTGTTCCG CATCGGGGAC 
CTTGTGGCCA TGGCTGGAGG GGACTTTGAG GACCTGGCCT TGCTGGGTGG TGCTGTGGGC 
ATCAGCATTC ACTGGGATTG CAACCTGGAC ACGAAAGGCT CTGACTGCTG TCCCCAGTAC 
TCCTTCCAGC TGCAGCAGAA AGGGTACAAC TTCAGGACAG CCAATCACTG GTGGGCAGCC 
TCAGGCGTGG AGACCCGGAG CCTGCTCAAG CTCTATGGAA TCCGTTTTGA CATTCTTGTC 
ACTGGGCAGG CAGGGAAGTT CGCGCTCATC CCTACGGCCA TCACAGTGGG CACAGGAGCG 
GCTTGGCTGG GCATGGTCAC CTTCCTCTGT GACCTGCTGC TACTGTATGT GGATAGAGAG 
GCCGGTTTCT ACTGGAGAAC CAAATATGAA GAGGCAAGAG CCCCAAAGAC GACTACCAAC 
AGTTCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001153033.1
CDS	130..1218
Translation	MQLQPAGTGNMASAAAAALVSWGFLDYKTEKYVLTRNCRVGVSQRLLQLAVVVYVIGWALLAKKGYQERDLAPQTSVITKLKGVSVTQVKELENRLWDVADFVKPSQGENVFFLVTNFLVTPAQVQGRCPEHPSVPLANCWADEDCPEGETGTYSHGIKTGQCVVFNGTHRTCEIWSWCPVESGAVPRSNALLTWDNTYFKHCLYDPLSSPYCPVFRIGDLVAMAGGDFEDLALLGGAVGISIHWDCNLDTKGSDCCPQYSFQLQQKGYNFRTANHWWAASGVETRSLLKLYGIRFDILVTGQAGKFALIPTAITVGTGAAWLGMVTFLCDLLLLYVDREAGFYWRTKYEEARAPKTTTNSS

Target ORF information:

RefSeq Version	NM_001159561.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus purinergic receptor P2X, ligand-gated ion channel, 6 (P2rx6), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001159561.1

ORF Insert Sequence:

ATGCAGTTGC AGCCAGCAGG AACTGGGAAC ATGGCTTCTG CAGCCGCAGC AGCACTCGTG 
AGCTGGGGGT TTCTGGATTA CAAGACGGAG AAATATGTGC TAACCAGGAA CTGTCGGGTG 
GGCGTCTCCC AGAGGCTGCT GCAGCTGGCA GTGGTAGTCT ACGTGATAGG GTGGGCCCTC 
TTGGCCAAAA AAGGCTACCA GGAACGGGAC TTGGCCCCTC AGACTTCTGT CATCACCAAA 
CTCAAGGGGG TTTCTGTAAC CCAGGTTAAG GAGCTGGAGA ACCGGCTGTG GGACGTGGCT 
GACTTTGTGA AGCCATCACA GGGAGAGAAC GTGTTCTTCC TGGTAACCAA CTTCCTCGTG 
ACACCAGCTC AAGTCCAGGG CAGATGTCCA GAGCATCCTT CCGTTCCTCT GGCTAACTGC 
TGGGCTGATG AAGACTGCCC CGAAGGGGAG ACGGGGACAT ACAGCCATGG CATAAAAACT 
GGTCAGTGTG TGGTGTTCAA CGGAACCCAC AGGACCTGTG AGATCTGGAG CTGGTGCCCA 
GTGGAGAGTG GTGCTGTGCC CAGATCCAAT GCCTTATTAA CCTGGGACAA CACATATTTC 
AAGCATTGTC TCTATGATCC ACTCTCCAGT CCGTACTGCC CAGTGTTCCG CATCGGGGAC 
CTTGTGGCCA TGGCTGGAGG GGACTTTGAG GACCTGGCCT TGCTGGGTGG TGCTGTGGGC 
ATCAGCATTC ACTGGGATTG CAACCTGGAC ACGAAAGGCT CTGACTGCTG TCCCCAGTAC 
TCCTTCCAGC TGCAGCAGAA AGGGTACAAC TTCAGGACAG CCAATCACTG GTGGGCAGCC 
TCAGGCGTGG AGACCCGGAG CCTGCTCAAG CTCTATGGAA TCCGTTTTGA CATTCTTGTC 
ACTGGGCAGG CAGGGAAGTT CGCGCTCATC CCTACGGCCA TCACAGTGGG CACAGGAGCG 
GCTTGGCTGG GCATGGTCAC CTTCCTCTGT GACCTGCTGC TACTGTATGT GGATAGAGAG 
GCCGGTTTCT ACTGGAGAAC CAAATATGAA GAGGCAAGAG CCCCAAAGAC GACTACCAAC 
AGTTCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

P2rx6 ( XM_006521856.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006521919.1 Mus musculus purinergic receptor P2X, ligand-gated ion channel, 6 (P2rx6), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu51925
Clone ID Related Accession (Same CDS sequence)	XM_006521856.2
Accession Version	XM_006521856.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 861bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	P2X purinoceptor 6 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000082.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 9, 2015 this sequence version replaced XM_006521856.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAGTTGC AGCCAGCAGG AACTGGGAAC ATGGCTTCTG CAGCCGCAGC AGCACTCGTG 
AGCTGGGGGT TTCTGGATTA CAAGACGGAG AAATATGTGC TAACCAGGAA CTGTCGGGTG 
GGCGTCTCCC AGAGGCTGCT GCAGCTGGCA GTGGTAGTCT ACGTGATAGG GTGGGCCCTC 
TTGGCCAAAA AAGGCTACCA GGAACGGGAC TTGGCCCCTC AGACTTCTGT CATCACCAAA 
CTCAAGGGGG TTTCTGTAAC CCAGGTTAAG GAGCTGGAGA ACCGGCTGTG GGACGTGGCT 
GACTTTGTGA AGCCATCACA GGGAGAGAAC GTGTTCTTCC TGGTAACCAA CTTCCTCGTG 
ACACCAGCTC AAGTCCAGGG CAGATGTCCA GAGCATCCTT CCGTTCCTCT GGCTAACTGC 
TGGGCTGATG AAGACTGCCC CGAAGGGGAG ACGGGGACAT ACAGCCATGG CATAAAAACT 
GGTCAGTGTG TGGTGTTCAA CGGAACCCAC AGGACCTGTG AGATCTGGAG CTGGTGCCCA 
GTGGAGAGTG GTGCTGTGCC CAGGAAGCCC CTGCTAGCTC AGGCCAAGAA CTTCACACTC 
TTCATCAAAA ATACTGTAAC CTTCAGCAAG TTCAACTTCT CCAGATCCAA TGCCTTATTA 
ACCTGGGACA ACACATATTT CAAGCATTGT CTCTATGATC CACTCTCCAG TCCGTACTGC 
CCAGTGTTCC GCATCGGGGA CCTTGTGGCC ATGGCTGGAG GGGACTTTGA GGACCTGGCC 
TTGCTGGACA GCCAATCACT GGTGGGCAGC CTCAGGCGTG GAGACCCGGA GCCTGCTCAA 
GCTCTATGGA ATCCGTTTTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006521919.1
CDS	160..1020
Translation	MQLQPAGTGNMASAAAAALVSWGFLDYKTEKYVLTRNCRVGVSQRLLQLAVVVYVIGWALLAKKGYQERDLAPQTSVITKLKGVSVTQVKELENRLWDVADFVKPSQGENVFFLVTNFLVTPAQVQGRCPEHPSVPLANCWADEDCPEGETGTYSHGIKTGQCVVFNGTHRTCEIWSWCPVESGAVPRKPLLAQAKNFTLFIKNTVTFSKFNFSRSNALLTWDNTYFKHCLYDPLSSPYCPVFRIGDLVAMAGGDFEDLALLDSQSLVGSLRRGDPEPAQALWNPF

Target ORF information:

RefSeq Version	XM_006521856.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus purinergic receptor P2X, ligand-gated ion channel, 6 (P2rx6), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006521856.2

ORF Insert Sequence:

ATGCAGTTGC AGCCAGCAGG AACTGGGAAC ATGGCTTCTG CAGCCGCAGC AGCACTCGTG 
AGCTGGGGGT TTCTGGATTA CAAGACGGAG AAATATGTGC TAACCAGGAA CTGTCGGGTG 
GGCGTCTCCC AGAGGCTGCT GCAGCTGGCA GTGGTAGTCT ACGTGATAGG GTGGGCCCTC 
TTGGCCAAAA AAGGCTACCA GGAACGGGAC TTGGCCCCTC AGACTTCTGT CATCACCAAA 
CTCAAGGGGG TTTCTGTAAC CCAGGTTAAG GAGCTGGAGA ACCGGCTGTG GGACGTGGCT 
GACTTTGTGA AGCCATCACA GGGAGAGAAC GTGTTCTTCC TGGTAACCAA CTTCCTCGTG 
ACACCAGCTC AAGTCCAGGG CAGATGTCCA GAGCATCCTT CCGTTCCTCT GGCTAACTGC 
TGGGCTGATG AAGACTGCCC CGAAGGGGAG ACGGGGACAT ACAGCCATGG CATAAAAACT 
GGTCAGTGTG TGGTGTTCAA CGGAACCCAC AGGACCTGTG AGATCTGGAG CTGGTGCCCA 
GTGGAGAGTG GTGCTGTGCC CAGGAAGCCC CTGCTAGCTC AGGCCAAGAA CTTCACACTC 
TTCATCAAAA ATACTGTAAC CTTCAGCAAG TTCAACTTCT CCAGATCCAA TGCCTTATTA 
ACCTGGGACA ACACATATTT CAAGCATTGT CTCTATGATC CACTCTCCAG TCCGTACTGC 
CCAGTGTTCC GCATCGGGGA CCTTGTGGCC ATGGCTGGAG GGGACTTTGA GGACCTGGCC 
TTGCTGGACA GCCAATCACT GGTGGGCAGC CTCAGGCGTG GAGACCCGGA GCCTGCTCAA 
GCTCTATGGA ATCCGTTTTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie SM,Fuchs H,Gailus-Durner V,Galli A,Gambadoro A,Gallegos J,Guo S,Horner NR,Hsu CW,Johnson SJ,Kalaga S,Keith LC,Lanoue L,Lawson TN,Lek M,Mark M,Marschall S,Mason J,McElwee ML,Newbigging S,Nutter LM,Peterson KA,Ramirez-Solis R,Rowland DJ,Ryder E,Samocha KE,Seavitt JR,Selloum M,Szoke-Kovacs Z,Tamura M,Trainor AG,Tudose I,Wakana S,Warren J,Wendling O,West DB,Wong L,Yoshiki A,,,,,,,,,MacArthur DG,Tocchini-Valentini GP,Gao X,Flicek P,Bradley A,Skarnes WC,Justice MJ,Parkinson HE,Moore M,Wells S,Braun RE,Svenson KL,de Angelis MH,Herault Y,Mohun T,Mallon AM,Henkelman RM,Brown SD,Adams DJ,Lloyd KC,McKerlie C,Beaudet AL,Bu?an M,Murray SA

P2X6 Knockout Mice Exhibit Normal Electrolyte Homeostasis.
PloS one11(6)e0156803(2016)
de Baaij JH,Kompatscher A,Viering DH,Bos C,Bindels RJ,Hoenderop JG

Mouse and human CRKL is dosage sensitive for cardiac outflow tract formation.
American journal of human genetics96(2)235-44(2015 Feb)
Racedo SE,McDonald-McGinn DM,Chung JH,Goldmuntz E,Zackai E,Emanuel BS,Zhou B,Funke B,Morrow BE

Age-related nuclear translocation of P2X6 subunit modifies splicing activity interacting with splicing factor 3A1.
PloS one10(4)e0123121(2015)
D?az-Hern?ndez JI,Sebasti?n-Serrano ?,G?mez-Villafuertes R,D?az-Hern?ndez M,Miras-Portugal MT

P2X receptors are expressed on neurons containing luteinizing hormone-releasing hormone in the mouse hypothalamus.
Neuroscience letters458(1)32-6(2009 Jul)
Fu J,Yu Q,Guo W,He C,Burnstock G,Xiang Z

- Most Popular Services
  - 人工遺伝子合成& DNA合成-納期保証
- Services & Products

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

P2rx6 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報