Slc2a10 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Slc2a10
Entrez Gene ID	170441
Full Name	solute carrier family 2 (facilitated glucose transporter), member 10
Synonyms	AA450473,Glut10
General protein information	Preferred Names solute carrier family 2 (facilitated glucose transporter), member 10 Names solute carrier family 2, facilitated glucose transporter member 10 glucose transporter type 10
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 2 Map Location: 2 H3\|2 85.66 cM
Summary	This gene encodes a class III facilitative glucose transporter. Mutations in the related gene in human are associated with arterial tortuosity syndrome. [provided by RefSeq, Dec 2013].

mRNA and Protein(s)

mRNA	Protein	Name
NM_130451.3	NP_569718.1	solute carrier family 2, facilitated glucose transporter member 10

Pathways from BioSystems

Homologies

Homo sapiens (human)	SLC2A10	NP_110404.1
	SLC2A10	XP_001107356.2
Bos taurus (cattle)	SLC2A10	NP_001179368.1
Gallus gallus (chicken)	SLC2A10	XP_417383.3
Danio rerio (zebrafish)	slc2a10	NP_001104633.1
Canis lupus familiaris (dog)	SLC2A10	XP_005635193.1
Xenopus tropicalis (tropical clawed frog)	slc2a10	NP_001072926.1
Pan troglodytes (chimpanzee)	SLC2A10	XP_003317028.1
Mus musculus (house mouse)	Slc2a10	NP_569718.1
Rattus norvegicus (Norway rat)	Slc2a10	NP_001102433.1

Gene Ontology
Bibliography

Related articles in PubMed

GLUT10 maintains the integrity of major arteries through regulation of redox homeostasis and mitochondrial function.
Syu YW, Lai HW, Jiang CL, Tsai HY, Lin CC, Lee YC
Human molecular genetics27(2)307-321(2018 Jan)

Radial glia require PDGFD-PDGFR? signalling in human but not mouse neocortex.
Lui JH, Nowakowski TJ, Pollen AA, Javaherian A, Kriegstein AR, Oldham MC
Nature515(7526)264-8(2014 Nov)

Increased gene expression of glucose transporters in the mouse brain after treatment with fluoxetine and pergolide.
Nagai K, Inoue T, Konishi H
Drug research64(7)389-91(2014 Jul)

Mitochondrial GLUT10 facilitates dehydroascorbic acid import and protects cells against oxidative stress: mechanistic insight into arterial tortuosity syndrome.
Lee YC, Huang HY, Chang CJ, Cheng CH, Chen YT
Human molecular genetics19(19)3721-33(2010 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

GLUT10 protects cells from oxidative injury.
Title: Mitochondrial GLUT10 facilitates dehydroascorbic acid import and protects cells against oxidative stress: mechanistic insight into arterial tortuosity syndrome.

report that two mouse models, homozygous respectively for G128E and S150F missense substitutions in glut10 do not present any of the vascular, anatomical, or immunohistological abnormalities as encountered in human Arterial tortuosity syndrome patients.
Title: Absence of arterial phenotype in mice with homozygous slc2A10 missense substitutions.

expression in adipose tissue
Title: Expression of Class III facilitative glucose transporter genes (GLUT-10 and GLUT-12) in mouse and human adipose tissues.

The following Slc2a10 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Slc2a10 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu09778	NM_130451.3 Latest version!	Mus musculus solute carrier family 2 (facilitated glucose transporter), member 10 (Slc2a10), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Slc2a10 ( NM_130451.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_569718.1 Mus musculus solute carrier family 2 (facilitated glucose transporter), member 10 (Slc2a10), mRNA.

Price & Availability↑

CloneID	OMu09778
Clone ID Related Accession (Same CDS sequence)	NM_130451.3
Accession Version	NM_130451.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1611bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-01
Organism	Mus musculus(house mouse)
Product	solute carrier family 2, facilitated glucose transporter member 10
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BY230011.1, AK052156.1 and BB732254.1. On Dec 19, 2013 this sequence version replaced NM_130451.2. ##Evidence-Data-START## Transcript exon combination :: AK052156.1, AY029579.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGGGCCTTC GCCCAGCTGT CCTCCTGCTC TGTGCCTCTG TGTCTTTGCT GGGGGGCCTG 
ACCTTCGGAT ATGAGCTGGC CGTCATATCT GGTGCCCTCC TACCACTCCA GCTGAACTTC 
GGGCTGAGTT GCCTCGAACA GGAGCTCCTG GTGGGCAGTC TGCTCTTGGG TGCTCTCCTC 
GCCTCCCTTG TCGGGGGCTT CCTCATTGAC TGCTATGGCA GGAGACGAGC CATCCTAGGG 
AGCAATGCGG TGCTGCTGGC TGGCAGCCTG ATTCTGGGTC TGGCCAGCTC CCTGCCCTGG 
CTGCTCCTGG GCCGTTTATC TGTTGGCTTT GCCATCTCTC TGTCTTCCAT GGCTTGCTGT 
ATCTACGTGT CAGAATTGGT GGGGCCGCGG CAGAGGGGTG TGCTGGTGTC CCTCTACGAG 
GTGGGCATCA CTGTGGGCAT TCTGTTCTCT TACGGCCTCA ACTACGTCCT GGCTGGCAGC 
CCTTGGGGCT GGAGGCACAT GTTTGGCTGG GCAGCTGCAC CTGCTCTCCT ACAGTCACTC 
AGCCTCTTTC TTCTCCCTGC TGGTGCAGAG GGCACAGCAG CCCCCAAAGA CCTTATCCCA 
CTCCAGGGAA GGGAGACAAG CAAACCGGGC CTGGTGAAGC CACAGTACAG CTTTCTGGAC 
CTCTTCAGGG CCCAGGACGG CATGTGGAGC CGGACTGTAG TGGGGCTGGG GCTGGTGCTG 
TTTCAGCAGC TCACAGGACA GCCCAATGTG CTGTATTACG CCTCTACCAT CTTTCGCTCC 
GTTGGCTTCC ACGGGGGCTC CTCAGCTGTG CTGGCTTCTG TGGGGCTTGG CACGGTGAAG 
GTGGCTGCCA CCTTGGTCGC CACGGGGCTG GTGGACCGTG CAGGCCGCAG AGTCCTCCTG 
CTCTTTGGAT GCGCTCTCAT GGCCTTATCG GTCAGCGGCA TAGGCCTGGT CAGCTTTGCT 
GTGTCCCTGG ACTCTGGACC CAGCTGCCTG GCCACATCCA ATGCCAGCCA GCAGGTGGAT 
CTGCCTGGAA GCTCGGGTTT GCTTGTGCGT TCATCTCTGC CGCCAGTGCT ACACACCAAT 
GGGGACCAAG GACAGCTGGT CCTGTCAGTC ACTGAGAGAC CCATCCATCC AGTCATCACA 
GCATCCCTGG GACCAGTTCT GAACACTGCC TCCCCAGTTC CCACCAGTCC CATCCTTGAG 
CATACCCTGC TGTGCTGGTC TGCGCTGGTT TGCATGATGG TCTACGTGAG CGCCTTCTCG 
GTTGGCTTTG GACCAGTAAC CTGGTTGGTC CTCAGTGAGA TCTACCCAGC GGAGATCCGA 
GGGAGAGCCT TCGCCTTCTG CAGCAGCTTC AACTGGGCAG CTAACCTCTT TATCAGCCTC 
TCCTTCCTCG ACCTGATCGG TGCCATCGGC TTGGCTTGGA CCTTCCTGCT CTATGGGCTG 
ACCGCTGTCC TTGGCCTGGC TTTCATCTAC CTACTTGTTC CTGAAACCAA AGGACAGTCT 
TTAGCTGAAA TAGAGCAGCA GTTTCAGACA AGCAGGTTCC CTCTAAACTT TGGCCATAGG 
CAGCGCATCG GTATTCAGTA CCATCGCCTG GATGTCTCCT CAGCCTCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_569718.1
CDS	149..1759
Translation	MGLRPAVLLLCASVSLLGGLTFGYELAVISGALLPLQLNFGLSCLEQELLVGSLLLGALLASLVGGFLIDCYGRRRAILGSNAVLLAGSLILGLASSLPWLLLGRLSVGFAISLSSMACCIYVSELVGPRQRGVLVSLYEVGITVGILFSYGLNYVLAGSPWGWRHMFGWAAAPALLQSLSLFLLPAGAEGTAAPKDLIPLQGRETSKPGLVKPQYSFLDLFRAQDGMWSRTVVGLGLVLFQQLTGQPNVLYYASTIFRSVGFHGGSSAVLASVGLGTVKVAATLVATGLVDRAGRRVLLLFGCALMALSVSGIGLVSFAVSLDSGPSCLATSNASQQVDLPGSSGLLVRSSLPPVLHTNGDQGQLVLSVTERPIHPVITASLGPVLNTASPVPTSPILEHTLLCWSALVCMMVYVSAFSVGFGPVTWLVLSEIYPAEIRGRAFAFCSSFNWAANLFISLSFLDLIGAIGLAWTFLLYGLTAVLGLAFIYLLVPETKGQSLAEIEQQFQTSRFPLNFGHRQRIGIQYHRLDVSSAS

Target ORF information:

RefSeq Version	NM_130451.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus solute carrier family 2 (facilitated glucose transporter), member 10 (Slc2a10), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_130451.3

ORF Insert Sequence:

ATGGGCCTTC GCCCAGCTGT CCTCCTGCTC TGTGCCTCTG TGTCTTTGCT GGGGGGCCTG 
ACCTTCGGAT ATGAGCTGGC CGTCATATCT GGTGCCCTCC TACCACTCCA GCTGAACTTC 
GGGCTGAGTT GCCTCGAACA GGAGCTCCTG GTGGGCAGTC TGCTCTTGGG TGCTCTCCTC 
GCCTCCCTTG TCGGGGGCTT CCTCATTGAC TGCTATGGCA GGAGACGAGC CATCCTAGGG 
AGCAATGCGG TGCTGCTGGC TGGCAGCCTG ATTCTGGGTC TGGCCAGCTC CCTGCCCTGG 
CTGCTCCTGG GCCGTTTATC TGTTGGCTTT GCCATCTCTC TGTCTTCCAT GGCTTGCTGT 
ATCTACGTGT CAGAATTGGT GGGGCCGCGG CAGAGGGGTG TGCTGGTGTC CCTCTACGAG 
GTGGGCATCA CTGTGGGCAT TCTGTTCTCT TACGGCCTCA ACTACGTCCT GGCTGGCAGC 
CCTTGGGGCT GGAGGCACAT GTTTGGCTGG GCAGCTGCAC CTGCTCTCCT ACAGTCACTC 
AGCCTCTTTC TTCTCCCTGC TGGTGCAGAG GGCACAGCAG CCCCCAAAGA CCTTATCCCA 
CTCCAGGGAA GGGAGACAAG CAAACCGGGC CTGGTGAAGC CACAGTACAG CTTTCTGGAC 
CTCTTCAGGG CCCAGGACGG CATGTGGAGC CGGACTGTAG TGGGGCTGGG GCTGGTGCTG 
TTTCAGCAGC TCACAGGACA GCCCAATGTG CTGTATTACG CCTCTACCAT CTTTCGCTCC 
GTTGGCTTCC ACGGGGGCTC CTCAGCTGTG CTGGCTTCTG TGGGGCTTGG CACGGTGAAG 
GTGGCTGCCA CCTTGGTCGC CACGGGGCTG GTGGACCGTG CAGGCCGCAG AGTCCTCCTG 
CTCTTTGGAT GCGCTCTCAT GGCCTTATCG GTCAGCGGCA TAGGCCTGGT CAGCTTTGCT 
GTGTCCCTGG ACTCTGGACC CAGCTGCCTG GCCACATCCA ATGCCAGCCA GCAGGTGGAT 
CTGCCTGGAA GCTCGGGTTT GCTTGTGCGT TCATCTCTGC CGCCAGTGCT ACACACCAAT 
GGGGACCAAG GACAGCTGGT CCTGTCAGTC ACTGAGAGAC CCATCCATCC AGTCATCACA 
GCATCCCTGG GACCAGTTCT GAACACTGCC TCCCCAGTTC CCACCAGTCC CATCCTTGAG 
CATACCCTGC TGTGCTGGTC TGCGCTGGTT TGCATGATGG TCTACGTGAG CGCCTTCTCG 
GTTGGCTTTG GACCAGTAAC CTGGTTGGTC CTCAGTGAGA TCTACCCAGC GGAGATCCGA 
GGGAGAGCCT TCGCCTTCTG CAGCAGCTTC AACTGGGCAG CTAACCTCTT TATCAGCCTC 
TCCTTCCTCG ACCTGATCGG TGCCATCGGC TTGGCTTGGA CCTTCCTGCT CTATGGGCTG 
ACCGCTGTCC TTGGCCTGGC TTTCATCTAC CTACTTGTTC CTGAAACCAA AGGACAGTCT 
TTAGCTGAAA TAGAGCAGCA GTTTCAGACA AGCAGGTTCC CTCTAAACTT TGGCCATAGG 
CAGCGCATCG GTATTCAGTA CCATCGCCTG GATGTCTCCT CAGCCTCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

GLUT10 maintains the integrity of major arteries through regulation of redox homeostasis and mitochondrial function.
Human molecular genetics27(2)307-321(2018 Jan)
Syu YW,Lai HW,Jiang CL,Tsai HY,Lin CC,Lee YC

Radial glia require PDGFD-PDGFR? signalling in human but not mouse neocortex.
Nature515(7526)264-8(2014 Nov)
Lui JH,Nowakowski TJ,Pollen AA,Javaherian A,Kriegstein AR,Oldham MC

Increased gene expression of glucose transporters in the mouse brain after treatment with fluoxetine and pergolide.
Drug research64(7)389-91(2014 Jul)
Nagai K,Inoue T,Konishi H

Mitochondrial GLUT10 facilitates dehydroascorbic acid import and protects cells against oxidative stress: mechanistic insight into arterial tortuosity syndrome.
Human molecular genetics19(19)3721-33(2010 Oct)
Lee YC,Huang HY,Chang CJ,Cheng CH,Chen YT

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Slc2a10 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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