Gstp2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Gstp2
Entrez Gene ID	14869
Full Name	glutathione S-transferase, pi 2
Synonyms	GSTpiA,Gst-3,Gst3
General protein information	Preferred Names glutathione S-transferase, pi 2 Names glutathione S-transferase P 2 GST YF-YF GST class-pi GST-piA Gst p-2 gst P2
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 19 Map Location: 19 A\|19 3.75 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_181796.2	NP_861461.1	glutathione S-transferase P 2

Pathways from BioSystems

Homologies

Homo sapiens (human)	GSTP1	NP_000843.1
Mus musculus (house mouse)	Gm3934	XP_001478705.1
Canis lupus familiaris (dog)	GSTP1	NP_001239096.1
Bos taurus (cattle)	GSTP1	NP_803482.1
Mus musculus (house mouse)	Gstp1	NP_038569.1
Mus musculus (house mouse)	Gstp2	NP_861461.1
Rattus norvegicus (Norway rat)	Gstp1	NP_036709.1
Danio rerio (zebrafish)	gstp2	NP_001018349.1
Pan troglodytes (chimpanzee)	GSTP1	XP_001152516.2
	GSTP1	NP_001036141.1
Xenopus tropicalis (tropical clawed frog)	LOC101730710	XP_004917627.1
Xenopus tropicalis (tropical clawed frog)	gstp1	NP_001016641.1
Canis lupus familiaris (dog)	LOC611366	XP_854117.1
Danio rerio (zebrafish)	gstp1	NP_571809.1
Xenopus tropicalis (tropical clawed frog)	LOC100490385	XP_002941992.2

Gene Ontology
Bibliography

Related articles in PubMed

S-Glutathionylation of Keap1: a new role for glutathione S-transferase pi in neuronal protection.
Carvalho AN, Marques C, Guedes RC, Castro-Caldas M, Rodrigues E, van Horssen J, Gama MJ
FEBS letters590(10)1455-66(2016 05)

Genetic Deficiency of Glutathione S-Transferase P Increases Myocardial Sensitivity to Ischemia-Reperfusion Injury.
Conklin DJ, Guo Y, Jagatheesan G, Kilfoil PJ, Haberzettl P, Hill BG, Baba SP, Guo L, Wetzelberger K, Obal D, Rokosh DG, Prough RA, Prabhu SD, Velayutham M, Zweier JL, Hoetker JD, Riggs DW, Srivastava S, Bolli R, Bhatnagar A
Circulation research117(5)437-49(2015 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

GSTP1/2 are a critical regulators of hepatocyte proliferation in the initial phases of liver regeneration.
Title: Glutathione transferases P1/P2 regulate the timing of signaling pathway activations and cell cycle progression during mouse liver regeneration.

Matrin 3 interacts specifically with the heat shock proteins glucose-regulated protein 78, GRP75 and glutathione S-transferase pi isoform 2.
Title: Matrin 3 co-immunoprecipitates with the heat shock proteins glucose-regulated protein 78 (GRP78), GRP75 and glutathione S-transferase ? isoform 2 (GST?2) in thymoma cells.

Apc(Min/+)Gstp1/p2(-/-) (Gstp-null Apc(Min)) mice had a 6-fold increase in colon adenoma incidence, and a 50-fold increase in colorectal adenoma multiplicity, relative to Gstp-wt Apc(Min).
Title: Markedly enhanced colon tumorigenesis in Apc(Min) mice lacking glutathione S-transferase Pi.

GSTP protects against the endothelial dysfunction induced by tobacco smoke exposure and that this protection may be related to the detoxification of acrolein or other related cigarette smoke constituents.
Title: Glutathione-S-transferase P protects against endothelial dysfunction induced by exposure to tobacco smoke.

The downregulation of Gstp2 may induce an increase of oxidative damage in the pyramidal cells of the CA1 and CA3 regions and granular layer of the dentate gyrus, leading to structural and functional damage.
Title: Chronic restraint stress decreases the expression of glutathione S-transferase pi2 in the mouse hippocampus.

The following Gstp2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Gstp2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu01999	NM_181796.2 Latest version!	Mus musculus glutathione S-transferase, pi 2 (Gstp2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Gstp2 ( NM_181796.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_861461.1 Mus musculus glutathione S-transferase, pi 2 (Gstp2), mRNA.

Price & Availability↑

CloneID	OMu01999
Clone ID Related Accession (Same CDS sequence)	NM_181796.2
Accession Version	NM_181796.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 633bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-18
Organism	Mus musculus(house mouse)
Product	glutathione S-transferase P 2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC064781.1. On Mar 20, 2004 this sequence version replaced NM_181796.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC064781.1, BC094623.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849380 [ECO:0000348] ##Evidence-Data-END##

ATGCCGCCGT ACACCATTGT CTACTTCCCA AGTCCAGGGC GGTGTGAGGC CATGCGCATG 
CTGCTGGCTG ACCAGGGCCA GAGCTGGAAG GAGGAGGTGG TTACCATAGA TACCTGGATG 
CAAGGCTTGC TCAAGCCCAC TTGTCTGTAT GGGCAGCTCC CCAAGTTTGA GGATGGAGAC 
CTCACCCTTT ACCAATCTAA TGCCATCTTG AGACACCTTG GCCGCTCTTT GGGGCTTTAT 
GGGAAAAACC AGAGGGAGGC CGCCCAGGTG GATATGGTGA ATGATGGGGT GGAGGACCTT 
CGCGGCAAAT ATGGCACCAT GATCTACAGA AACTATGAGA ATGGTAAGAA TGACTACGTG 
AAGGCCCTGC CTGGGCATCT GAAGCCTTTT GAGACCCTGC TGTCCCAGAA CCAGGGAGGC 
AAAGCTTTCA TCGTGGGTGA CCAGATCTCC TTTGCCGATT ACAACTTGCT GGACCTGCTG 
CTGATCCACC AAGTCCTGGC CCCTGGCTGC CTGGACAACT TCCCCCTGCT CTCTGCCTAT 
GTGGCTCGCC TCAGTGCCCG GCCCAAGATC AAGGCCTTTC TGTCCTCCCC GGAACATGTG 
AACCGTCCCA TCAATGGCAA TGGCAAACAG TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_861461.1
CDS	57..689
Translation	MPPYTIVYFPSPGRCEAMRMLLADQGQSWKEEVVTIDTWMQGLLKPTCLYGQLPKFEDGDLTLYQSNAILRHLGRSLGLYGKNQREAAQVDMVNDGVEDLRGKYGTMIYRNYENGKNDYVKALPGHLKPFETLLSQNQGGKAFIVGDQISFADYNLLDLLLIHQVLAPGCLDNFPLLSAYVARLSARPKIKAFLSSPEHVNRPINGNGKQ

Target ORF information:

RefSeq Version	NM_181796.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus glutathione S-transferase, pi 2 (Gstp2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_181796.2

ORF Insert Sequence:

ATGCCGCCGT ACACCATTGT CTACTTCCCA AGTCCAGGGC GGTGTGAGGC CATGCGCATG 
CTGCTGGCTG ACCAGGGCCA GAGCTGGAAG GAGGAGGTGG TTACCATAGA TACCTGGATG 
CAAGGCTTGC TCAAGCCCAC TTGTCTGTAT GGGCAGCTCC CCAAGTTTGA GGATGGAGAC 
CTCACCCTTT ACCAATCTAA TGCCATCTTG AGACACCTTG GCCGCTCTTT GGGGCTTTAT 
GGGAAAAACC AGAGGGAGGC CGCCCAGGTG GATATGGTGA ATGATGGGGT GGAGGACCTT 
CGCGGCAAAT ATGGCACCAT GATCTACAGA AACTATGAGA ATGGTAAGAA TGACTACGTG 
AAGGCCCTGC CTGGGCATCT GAAGCCTTTT GAGACCCTGC TGTCCCAGAA CCAGGGAGGC 
AAAGCTTTCA TCGTGGGTGA CCAGATCTCC TTTGCCGATT ACAACTTGCT GGACCTGCTG 
CTGATCCACC AAGTCCTGGC CCCTGGCTGC CTGGACAACT TCCCCCTGCT CTCTGCCTAT 
GTGGCTCGCC TCAGTGCCCG GCCCAAGATC AAGGCCTTTC TGTCCTCCCC GGAACATGTG 
AACCGTCCCA TCAATGGCAA TGGCAAACAG TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

S-Glutathionylation of Keap1: a new role for glutathione S-transferase pi in neuronal protection.
FEBS letters590(10)1455-66(2016 05)
Carvalho AN,Marques C,Guedes RC,Castro-Caldas M,Rodrigues E,van Horssen J,Gama MJ

Genetic Deficiency of Glutathione S-Transferase P Increases Myocardial Sensitivity to Ischemia-Reperfusion Injury.
Circulation research117(5)437-49(2015 Aug)
Conklin DJ,Guo Y,Jagatheesan G,Kilfoil PJ,Haberzettl P,Hill BG,Baba SP,Guo L,Wetzelberger K,Obal D,Rokosh DG,Prough RA,Prabhu SD,Velayutham M,Zweier JL,Hoetker JD,Riggs DW,Srivastava S,Bolli R,Bhatnagar A

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Gstp2 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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