Gbp2b cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Gbp2b
Entrez Gene ID	14468
Full Name	guanylate binding protein 2b
Synonyms	Gbp-1,Gbp1,Mag-1,Mpa-1,Mpa1
General protein information	Preferred Names guanylate binding protein 2b Names guanylate-binding protein 1 GTP-binding protein 1 guanylate nucleotide binding protein 1 interferon-gamma-inducible protein MAG-1 interferon-induced guanylate-binding protein 1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 3 Map Location: 3 H1\|3 66.69 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_010259.2	NP_034389.2	guanylate-binding protein 1
XM_030252421.1	XP_030108281.1	guanylate-binding protein 1 isoform X1
XM_011240014.1	XP_011238316.1	guanylate-binding protein 1 isoform X2

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Gbp2b	NP_034389.2
Homo sapiens (human)	GBP3	NP_060754.2
Pan troglodytes (chimpanzee)	GBP3	XP_001146987.1

Gene Ontology
Bibliography

Related articles in PubMed

Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA.
Liu X, Jiao Y, Cao Y, Deng N, Ma Y, Hasty KA, Kang A, Chen H, Stuart JM, Gu W
BMC immunology17(1)25(2016 08)

Guanylate binding proteins enable rapid activation of canonical and noncanonical inflammasomes in Chlamydia-infected macrophages.
Finethy R, Jorgensen I, Haldar AK, de Zoete MR, Strowig T, Flavell RA, Yamamoto M, Nagarajan UM, Miao EA, Coers J
Infection and immunity83(12)4740-9(2015 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

GBP1 GBP2 enable rapid activation of canonical and noncanonical inflammasomes in Chlamydia-infected macrophages.
Title: Guanylate binding proteins enable rapid activation of canonical and noncanonical inflammasomes in Chlamydia-infected macrophages.

These findings demonstrate that Gbp1 plays an important role in the IFN-gamma-dependent, cell-autonomous control of toxoplasmosis and predict a broader role for this protein in host defense.
Title: Guanylate-binding protein 1 (Gbp1) contributes to cell-autonomous immunity against Toxoplasma gondii.

findings show that at least 4 IFN-gamma-inducible Gbps--Gbp1, Gbp6, Gbp7, and Gbp10--conferred cell-autonomous immunity to listerial or mycobacterial infection within macrophages and gene-deficient animals
Title: A family of IFN-?-inducible 65-kD GTPases protects against bacterial infection.

ROP16, ROP18, and GRA15 are parasitic virulence factors that determine strain-specific accumulation of mGBP1 on the parasitophorous vacuole
Title: Determinants of GBP recruitment to Toxoplasma gondii vacuoles and the parasitic factors that control it.

These findings identify a role for IFN-alphaA-mediated GBP-1 expression in the prevention of intestinal epithelial apoptosis by commensal bacteria.
Title: Commensal Escherichia coli reduces epithelial apoptosis through IFN-alphaA-mediated induction of guanylate binding protein-1 in human and murine models of developing intestine.

The following Gbp2b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Gbp2b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu23551	NM_010259.2 Latest version!	Mus musculus guanylate binding protein 2b (Gbp2b), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OMu67807	XM_011240014.1 Latest version!	Mus musculus guanylate binding protein 2b (Gbp2b), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OMu23551	XM_030252421.1 Latest version!	Mus musculus guanylate binding protein 2b (Gbp2b), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Gbp2b ( NM_010259.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_034389.2 Mus musculus guanylate binding protein 2b (Gbp2b), mRNA.

Price & Availability↑

CloneID	OMu23551
Clone ID Related Accession (Same CDS sequence)	NM_010259.2 , XM_030252421.1
Accession Version	NM_010259.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1770bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-25
Organism	Mus musculus(house mouse)
Product	guanylate-binding protein 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK077796.1 and AC102108.12. On Mar 23, 2007 this sequence version replaced NM_010259.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK077796.1, EF494422.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164133 [ECO:0000348] ##Evidence-Data-END##

ATGGCCTCAG AAATCCACAT GAAAGGCCCA GTGTGCCTCA TCAAGAACTC CGGTGAGCAG 
TTGGAGGTCT ACCAGGAAGC ACTGGACATC CTGTCTGCTA TCCAAAATCC TGTGGTGGTC 
GTAGCAATAG TGGGCTTCTA CCACACAGGC AAATCCTATC TGATGAATAA GCTGGCTGGA 
AAGCAGAAGG GCTTCTCCCT GGGCTCCACT GTGCAGTCTC ACACAAAGGG CATCTGGATG 
TGGTGCATGC CTCATCCCGA GAAGCCAGAA CATACCCTGG TTCTGCTTGA CACTGAGGGC 
CTGAAAGACA TGCAGAAGGG TGACAACCAG AATGACTGTT GGATCTTTGC TTTGGCAGTC 
CTCCTCAGCA GCACCTTCAT CTACAACAGC ATAGGAACCA TCAACCAGCA GGCCATGGAC 
CAGCTGCACT ATGTGACAGA ACTGACTGAT CTCATCAAAT CAAAGTCATC ACCTGATCAG 
AGTGATGTAG ACAACTCAGC TAACTTTGTG GGCTTTTTTC CTATCTTTGT GTGGACTCTG 
AGGGATTTCT CCCTGGATCT GGAATTTGAT GGAGAATCCA TCACTCCTGA TGAGTACCTG 
GAGACTTCAC TGGCTCTGAG AAAAGGAACT GATGAGAACA CTAAAAAATT TAATATGCCT 
CGCCTGTGTA TCAGGAAGTT CTTCCCAAAG AGGAAGTGCT TCATCTTTGA CAGGCCTGGA 
GACAGGAAGC AACTTTCCAA ACTAGAGTGG ATACAGGAGG ACCAGCTGAA TAAAGAATTT 
GTAGAACAAG TTGCAGAATT CACCTCATAC ATCTTCAGCT ATTCTGGTGT CAAGACTCTA 
TCTGGAGGCA TCACAGTCAA TGGGCCACGT CTAAAAAGCC TGGTGCAGAC CTATGTCAGT 
GCCATCTGCA GTGGAGAACT ACCCTGTATG GAGAACGCAG TCCTGACTTT GGCCCAGATA 
GAGAACTCAG CAGCAGTGCA AAAGGCCATC ACCTACTACG AAGAACAGAT GAATCAGAAG 
ATCCACATGC CCACAGAAAC CCTCCAGGAG CTCCTGGATC TGCACAGGAC CTGTGAGAGG 
GAGGCCATTG AGGTCTTCAT GAAGAATTCT TTCAAGGATG TAGACCAGAA GTTCCAGGAA 
GAATTAGGGG CCCAGCTGGA AGCCAAACGA GATGCCTTTG TTAAGAAGAA CATGGACATG 
TCATCTGCTC ATTGCTCAGA CTTACTGGAG GGCCTCTTTG CTCATCTGGA AGAAGAAGTG 
AAGCAGGGGA CATTTTATAA ACCAGGAGGC TACTACCTTT TTCTTCAAAG GAAACAAGAG 
CTGGAGAAAA AGTATATCCA GACTCCTGGA AAGGGACTCC AGGCTGAAGT GATGCTGAGA 
AAATACTTTG AATCCAAGGA GGATTTGGCT GATACACTTC TAAAGATGGA CCAGTCACTC 
ACAGAAAAGG AAAAGCAGAT TGAAATGGAA CGTATAAAAG CAGAAGCCGC AGAAGCAGCA 
AATAGAGCAT TGGCAGAAAT GCAAAAGAAG CATGAGATGC TGATGGAACA GAAGGAACAG 
AGTTATCAAG AGCACATGAA ACAGCTGACT GAGAAGATGG AGCAGGAACG GAAAGAGTTA 
ATGGCAGAGC AACAAAGAAT CATATCCCTT AAACTTCAGG AACAGGAAAG ACTTCTCAAG 
CAAGGATTCC AGAATGAGAG CTTGCAACTA CGTCAAGAGA TAGAGAAAAT CAAGAACATG 
CCTCCACCTC GATCATGCAC CATACTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_034389.2
CDS	80..1849
Translation	MASEIHMKGPVCLIKNSGEQLEVYQEALDILSAIQNPVVVVAIVGFYHTGKSYLMNKLAGKQKGFSLGSTVQSHTKGIWMWCMPHPEKPEHTLVLLDTEGLKDMQKGDNQNDCWIFALAVLLSSTFIYNSIGTINQQAMDQLHYVTELTDLIKSKSSPDQSDVDNSANFVGFFPIFVWTLRDFSLDLEFDGESITPDEYLETSLALRKGTDENTKKFNMPRLCIRKFFPKRKCFIFDRPGDRKQLSKLEWIQEDQLNKEFVEQVAEFTSYIFSYSGVKTLSGGITVNGPRLKSLVQTYVSAICSGELPCMENAVLTLAQIENSAAVQKAITYYEEQMNQKIHMPTETLQELLDLHRTCEREAIEVFMKNSFKDVDQKFQEELGAQLEAKRDAFVKKNMDMSSAHCSDLLEGLFAHLEEEVKQGTFYKPGGYYLFLQRKQELEKKYIQTPGKGLQAEVMLRKYFESKEDLADTLLKMDQSLTEKEKQIEMERIKAEAAEAANRALAEMQKKHEMLMEQKEQSYQEHMKQLTEKMEQERKELMAEQQRIISLKLQEQERLLKQGFQNESLQLRQEIEKIKNMPPPRSCTIL

Target ORF information:

RefSeq Version	NM_010259.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus guanylate binding protein 2b (Gbp2b), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_010259.2

ORF Insert Sequence:

ATGGCCTCAG AAATCCACAT GAAAGGCCCA GTGTGCCTCA TCAAGAACTC CGGTGAGCAG 
TTGGAGGTCT ACCAGGAAGC ACTGGACATC CTGTCTGCTA TCCAAAATCC TGTGGTGGTC 
GTAGCAATAG TGGGCTTCTA CCACACAGGC AAATCCTATC TGATGAATAA GCTGGCTGGA 
AAGCAGAAGG GCTTCTCCCT GGGCTCCACT GTGCAGTCTC ACACAAAGGG CATCTGGATG 
TGGTGCATGC CTCATCCCGA GAAGCCAGAA CATACCCTGG TTCTGCTTGA CACTGAGGGC 
CTGAAAGACA TGCAGAAGGG TGACAACCAG AATGACTGTT GGATCTTTGC TTTGGCAGTC 
CTCCTCAGCA GCACCTTCAT CTACAACAGC ATAGGAACCA TCAACCAGCA GGCCATGGAC 
CAGCTGCACT ATGTGACAGA ACTGACTGAT CTCATCAAAT CAAAGTCATC ACCTGATCAG 
AGTGATGTAG ACAACTCAGC TAACTTTGTG GGCTTTTTTC CTATCTTTGT GTGGACTCTG 
AGGGATTTCT CCCTGGATCT GGAATTTGAT GGAGAATCCA TCACTCCTGA TGAGTACCTG 
GAGACTTCAC TGGCTCTGAG AAAAGGAACT GATGAGAACA CTAAAAAATT TAATATGCCT 
CGCCTGTGTA TCAGGAAGTT CTTCCCAAAG AGGAAGTGCT TCATCTTTGA CAGGCCTGGA 
GACAGGAAGC AACTTTCCAA ACTAGAGTGG ATACAGGAGG ACCAGCTGAA TAAAGAATTT 
GTAGAACAAG TTGCAGAATT CACCTCATAC ATCTTCAGCT ATTCTGGTGT CAAGACTCTA 
TCTGGAGGCA TCACAGTCAA TGGGCCACGT CTAAAAAGCC TGGTGCAGAC CTATGTCAGT 
GCCATCTGCA GTGGAGAACT ACCCTGTATG GAGAACGCAG TCCTGACTTT GGCCCAGATA 
GAGAACTCAG CAGCAGTGCA AAAGGCCATC ACCTACTACG AAGAACAGAT GAATCAGAAG 
ATCCACATGC CCACAGAAAC CCTCCAGGAG CTCCTGGATC TGCACAGGAC CTGTGAGAGG 
GAGGCCATTG AGGTCTTCAT GAAGAATTCT TTCAAGGATG TAGACCAGAA GTTCCAGGAA 
GAATTAGGGG CCCAGCTGGA AGCCAAACGA GATGCCTTTG TTAAGAAGAA CATGGACATG 
TCATCTGCTC ATTGCTCAGA CTTACTGGAG GGCCTCTTTG CTCATCTGGA AGAAGAAGTG 
AAGCAGGGGA CATTTTATAA ACCAGGAGGC TACTACCTTT TTCTTCAAAG GAAACAAGAG 
CTGGAGAAAA AGTATATCCA GACTCCTGGA AAGGGACTCC AGGCTGAAGT GATGCTGAGA 
AAATACTTTG AATCCAAGGA GGATTTGGCT GATACACTTC TAAAGATGGA CCAGTCACTC 
ACAGAAAAGG AAAAGCAGAT TGAAATGGAA CGTATAAAAG CAGAAGCCGC AGAAGCAGCA 
AATAGAGCAT TGGCAGAAAT GCAAAAGAAG CATGAGATGC TGATGGAACA GAAGGAACAG 
AGTTATCAAG AGCACATGAA ACAGCTGACT GAGAAGATGG AGCAGGAACG GAAAGAGTTA 
ATGGCAGAGC AACAAAGAAT CATATCCCTT AAACTTCAGG AACAGGAAAG ACTTCTCAAG 
CAAGGATTCC AGAATGAGAG CTTGCAACTA CGTCAAGAGA TAGAGAAAAT CAAGAACATG 
CCTCCACCTC GATCATGCAC CATACTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Gbp2b ( XM_011240014.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011238316.1 Mus musculus guanylate binding protein 2b (Gbp2b), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu67807
Clone ID Related Accession (Same CDS sequence)	XM_011240014.1
Accession Version	XM_011240014.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1680bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	guanylate-binding protein 1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000069.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCTCAG AAATCCACAT GAAAGGCCCA GTGTGCCTCA TCAAGAACTC CGGTGAGCAG 
TTGGAGGTCT ACCAGGAAGC ACTGGACATC CTGTCTGCTA TCCAAAATCC TGTGGTGGTC 
GTAGCAATAG TGGGCTTCTA CCACACAGGC AAATCCTATC TGATGAATAA GCTGGCTGGA 
AAGCAGAAGG GCTTCTCCCT GGGCTCCACT GTGCAGTCTC ACACAAAGGG CATCTGGATG 
TGGTGCATGC CTCATCCCGA GAAGCCAGAA CATACCCTGG TTCTGCTTGA CACTGAGGGC 
CTGAAAGACA TGCAGAAGGG TGACAACCAG AATGACTGTT GGATCTTTGC TTTGGCAGTC 
CTCCTCAGCA GCACCTTCAT CTACAACAGC ATAGGAACCA TCAACCAGCA GGCCATGGAC 
CAGCTGCACT ATGTGACAGA ACTGACTGAT CTCATCAAAT CAAAGTCATC ACCTGATCAG 
AGTGATGTAG ACAACTCAGC TAACTTTGTG GGCTTTTTTC CTATCTTTGT GTGGACTCTG 
AGGGATTTCT CCCTGGATCT GGAATTTGAT GGAGAATCCA TCACTCCTGA TGAGTACCTG 
GAGACTTCAC TGGCTCTGAG AAAAGGAACT GATGAGAACA CTAAAAAATT TAATATGCCT 
CGCCTGTGTA TCAGGAAGTT CTTCCCAAAG AGGAAGTGCT TCATCTTTGA CAGGCCTGGA 
GACAGGAAGC AACTTTCCAA ACTAGAGTGG ATACAGGAGG ACCAGCTGAA TAAAGAATTT 
GTAGAACAAG TTGCAGAATT CACCTCATAC ATCTTCAGCT ATTCTGGTGT CAAGACTCTA 
TCTGGAGGCA TCACAGTCAA TGGGCCACGT CTAAAAAGCC TGGTGCAGAC CTATGTCAGT 
GCCATCTGCA GTGGAGAACT ACCCTGTATG GAGAACGCAG TCCTGACTTT GGCCCAGATA 
GAGAACTCAG CAGCAGTGCA AAAGGCCATC ACCTACTACG AAGAACAGAT GAATCAGAAG 
ATCCACATGC CCACAGAAAC CCTCCAGGAG CTCCTGGATC TGCACAGGAC CTGTGAGAGG 
GAGGCCATTG AGGTCTTCAT GAAGAATTCT TTCAAGGATG TAGACCAGAA GTTCCAGGAA 
GAATTAGGGG CCCAGCTGGA AGCCAAACGA GATGCCTTTG TTAAGAAGAA CATGGACATG 
TCATCTGCTC ATTGCTCAGA CTTACTGGAG GGCCTCTTTG CTCATCTGGA AGAAGAAGTG 
AAGCAGGGGA CATTTTATAA ACCAGGAGGC TACTACCTTT TTCTTCAAAG GAAACAAGAG 
CTGGAGAAAA AGTATATCCA GACTCCTGGA AAGGGACTCC AGGCTGAAGT GATGCTGAGA 
AAATACTTTG AATCCAAGGA GGATTTGGCT GATACACTTC TAAAGATGGA CCAGTCACTC 
ACAGAAAAGG AAAAGCAGAT TGAAATGGAA CGTATAAAAG CAGAAGCCGC AGAAGCAGCA 
AATAGAGCAT TGGCAGAAAT GCAAAAGAAG CATGAGATGC TGATGGAACA GAAGGAACAG 
AGTTATCAAG AGCACATGAA ACAGCTGACT GAGAAGATGG AGCAGGAACG GAAAGAGTTA 
ATGGCAGAGC AACAAAGAAT CATATCCCTT AAACTTCAGG CAGAACAAAT TTCAGGTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011238316.1
CDS	111..1790
Translation	MASEIHMKGPVCLIKNSGEQLEVYQEALDILSAIQNPVVVVAIVGFYHTGKSYLMNKLAGKQKGFSLGSTVQSHTKGIWMWCMPHPEKPEHTLVLLDTEGLKDMQKGDNQNDCWIFALAVLLSSTFIYNSIGTINQQAMDQLHYVTELTDLIKSKSSPDQSDVDNSANFVGFFPIFVWTLRDFSLDLEFDGESITPDEYLETSLALRKGTDENTKKFNMPRLCIRKFFPKRKCFIFDRPGDRKQLSKLEWIQEDQLNKEFVEQVAEFTSYIFSYSGVKTLSGGITVNGPRLKSLVQTYVSAICSGELPCMENAVLTLAQIENSAAVQKAITYYEEQMNQKIHMPTETLQELLDLHRTCEREAIEVFMKNSFKDVDQKFQEELGAQLEAKRDAFVKKNMDMSSAHCSDLLEGLFAHLEEEVKQGTFYKPGGYYLFLQRKQELEKKYIQTPGKGLQAEVMLRKYFESKEDLADTLLKMDQSLTEKEKQIEMERIKAEAAEAANRALAEMQKKHEMLMEQKEQSYQEHMKQLTEKMEQERKELMAEQQRIISLKLQAEQISG

Target ORF information:

RefSeq Version	XM_011240014.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus guanylate binding protein 2b (Gbp2b), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011240014.1

ORF Insert Sequence:

ATGGCCTCAG AAATCCACAT GAAAGGCCCA GTGTGCCTCA TCAAGAACTC CGGTGAGCAG 
TTGGAGGTCT ACCAGGAAGC ACTGGACATC CTGTCTGCTA TCCAAAATCC TGTGGTGGTC 
GTAGCAATAG TGGGCTTCTA CCACACAGGC AAATCCTATC TGATGAATAA GCTGGCTGGA 
AAGCAGAAGG GCTTCTCCCT GGGCTCCACT GTGCAGTCTC ACACAAAGGG CATCTGGATG 
TGGTGCATGC CTCATCCCGA GAAGCCAGAA CATACCCTGG TTCTGCTTGA CACTGAGGGC 
CTGAAAGACA TGCAGAAGGG TGACAACCAG AATGACTGTT GGATCTTTGC TTTGGCAGTC 
CTCCTCAGCA GCACCTTCAT CTACAACAGC ATAGGAACCA TCAACCAGCA GGCCATGGAC 
CAGCTGCACT ATGTGACAGA ACTGACTGAT CTCATCAAAT CAAAGTCATC ACCTGATCAG 
AGTGATGTAG ACAACTCAGC TAACTTTGTG GGCTTTTTTC CTATCTTTGT GTGGACTCTG 
AGGGATTTCT CCCTGGATCT GGAATTTGAT GGAGAATCCA TCACTCCTGA TGAGTACCTG 
GAGACTTCAC TGGCTCTGAG AAAAGGAACT GATGAGAACA CTAAAAAATT TAATATGCCT 
CGCCTGTGTA TCAGGAAGTT CTTCCCAAAG AGGAAGTGCT TCATCTTTGA CAGGCCTGGA 
GACAGGAAGC AACTTTCCAA ACTAGAGTGG ATACAGGAGG ACCAGCTGAA TAAAGAATTT 
GTAGAACAAG TTGCAGAATT CACCTCATAC ATCTTCAGCT ATTCTGGTGT CAAGACTCTA 
TCTGGAGGCA TCACAGTCAA TGGGCCACGT CTAAAAAGCC TGGTGCAGAC CTATGTCAGT 
GCCATCTGCA GTGGAGAACT ACCCTGTATG GAGAACGCAG TCCTGACTTT GGCCCAGATA 
GAGAACTCAG CAGCAGTGCA AAAGGCCATC ACCTACTACG AAGAACAGAT GAATCAGAAG 
ATCCACATGC CCACAGAAAC CCTCCAGGAG CTCCTGGATC TGCACAGGAC CTGTGAGAGG 
GAGGCCATTG AGGTCTTCAT GAAGAATTCT TTCAAGGATG TAGACCAGAA GTTCCAGGAA 
GAATTAGGGG CCCAGCTGGA AGCCAAACGA GATGCCTTTG TTAAGAAGAA CATGGACATG 
TCATCTGCTC ATTGCTCAGA CTTACTGGAG GGCCTCTTTG CTCATCTGGA AGAAGAAGTG 
AAGCAGGGGA CATTTTATAA ACCAGGAGGC TACTACCTTT TTCTTCAAAG GAAACAAGAG 
CTGGAGAAAA AGTATATCCA GACTCCTGGA AAGGGACTCC AGGCTGAAGT GATGCTGAGA 
AAATACTTTG AATCCAAGGA GGATTTGGCT GATACACTTC TAAAGATGGA CCAGTCACTC 
ACAGAAAAGG AAAAGCAGAT TGAAATGGAA CGTATAAAAG CAGAAGCCGC AGAAGCAGCA 
AATAGAGCAT TGGCAGAAAT GCAAAAGAAG CATGAGATGC TGATGGAACA GAAGGAACAG 
AGTTATCAAG AGCACATGAA ACAGCTGACT GAGAAGATGG AGCAGGAACG GAAAGAGTTA 
ATGGCAGAGC AACAAAGAAT CATATCCCTT AAACTTCAGG CAGAACAAAT TTCAGGTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Gbp2b ( XM_030252421.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_030108281.1 Mus musculus guanylate binding protein 2b (Gbp2b), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu23551
Clone ID Related Accession (Same CDS sequence)	NM_010259.2 , XM_030252421.1
Accession Version	XM_030252421.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1770bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	guanylate-binding protein 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000069.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCTCAG AAATCCACAT GAAAGGCCCA GTGTGCCTCA TCAAGAACTC CGGTGAGCAG 
TTGGAGGTCT ACCAGGAAGC ACTGGACATC CTGTCTGCTA TCCAAAATCC TGTGGTGGTC 
GTAGCAATAG TGGGCTTCTA CCACACAGGC AAATCCTATC TGATGAATAA GCTGGCTGGA 
AAGCAGAAGG GCTTCTCCCT GGGCTCCACT GTGCAGTCTC ACACAAAGGG CATCTGGATG 
TGGTGCATGC CTCATCCCGA GAAGCCAGAA CATACCCTGG TTCTGCTTGA CACTGAGGGC 
CTGAAAGACA TGCAGAAGGG TGACAACCAG AATGACTGTT GGATCTTTGC TTTGGCAGTC 
CTCCTCAGCA GCACCTTCAT CTACAACAGC ATAGGAACCA TCAACCAGCA GGCCATGGAC 
CAGCTGCACT ATGTGACAGA ACTGACTGAT CTCATCAAAT CAAAGTCATC ACCTGATCAG 
AGTGATGTAG ACAACTCAGC TAACTTTGTG GGCTTTTTTC CTATCTTTGT GTGGACTCTG 
AGGGATTTCT CCCTGGATCT GGAATTTGAT GGAGAATCCA TCACTCCTGA TGAGTACCTG 
GAGACTTCAC TGGCTCTGAG AAAAGGAACT GATGAGAACA CTAAAAAATT TAATATGCCT 
CGCCTGTGTA TCAGGAAGTT CTTCCCAAAG AGGAAGTGCT TCATCTTTGA CAGGCCTGGA 
GACAGGAAGC AACTTTCCAA ACTAGAGTGG ATACAGGAGG ACCAGCTGAA TAAAGAATTT 
GTAGAACAAG TTGCAGAATT CACCTCATAC ATCTTCAGCT ATTCTGGTGT CAAGACTCTA 
TCTGGAGGCA TCACAGTCAA TGGGCCACGT CTAAAAAGCC TGGTGCAGAC CTATGTCAGT 
GCCATCTGCA GTGGAGAACT ACCCTGTATG GAGAACGCAG TCCTGACTTT GGCCCAGATA 
GAGAACTCAG CAGCAGTGCA AAAGGCCATC ACCTACTACG AAGAACAGAT GAATCAGAAG 
ATCCACATGC CCACAGAAAC CCTCCAGGAG CTCCTGGATC TGCACAGGAC CTGTGAGAGG 
GAGGCCATTG AGGTCTTCAT GAAGAATTCT TTCAAGGATG TAGACCAGAA GTTCCAGGAA 
GAATTAGGGG CCCAGCTGGA AGCCAAACGA GATGCCTTTG TTAAGAAGAA CATGGACATG 
TCATCTGCTC ATTGCTCAGA CTTACTGGAG GGCCTCTTTG CTCATCTGGA AGAAGAAGTG 
AAGCAGGGGA CATTTTATAA ACCAGGAGGC TACTACCTTT TTCTTCAAAG GAAACAAGAG 
CTGGAGAAAA AGTATATCCA GACTCCTGGA AAGGGACTCC AGGCTGAAGT GATGCTGAGA 
AAATACTTTG AATCCAAGGA GGATTTGGCT GATACACTTC TAAAGATGGA CCAGTCACTC 
ACAGAAAAGG AAAAGCAGAT TGAAATGGAA CGTATAAAAG CAGAAGCCGC AGAAGCAGCA 
AATAGAGCAT TGGCAGAAAT GCAAAAGAAG CATGAGATGC TGATGGAACA GAAGGAACAG 
AGTTATCAAG AGCACATGAA ACAGCTGACT GAGAAGATGG AGCAGGAACG GAAAGAGTTA 
ATGGCAGAGC AACAAAGAAT CATATCCCTT AAACTTCAGG AACAGGAAAG ACTTCTCAAG 
CAAGGATTCC AGAATGAGAG CTTGCAACTA CGTCAAGAGA TAGAGAAAAT CAAGAACATG 
CCTCCACCTC GATCATGCAC CATACTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_030108281.1
CDS	114..1883
Translation	MASEIHMKGPVCLIKNSGEQLEVYQEALDILSAIQNPVVVVAIVGFYHTGKSYLMNKLAGKQKGFSLGSTVQSHTKGIWMWCMPHPEKPEHTLVLLDTEGLKDMQKGDNQNDCWIFALAVLLSSTFIYNSIGTINQQAMDQLHYVTELTDLIKSKSSPDQSDVDNSANFVGFFPIFVWTLRDFSLDLEFDGESITPDEYLETSLALRKGTDENTKKFNMPRLCIRKFFPKRKCFIFDRPGDRKQLSKLEWIQEDQLNKEFVEQVAEFTSYIFSYSGVKTLSGGITVNGPRLKSLVQTYVSAICSGELPCMENAVLTLAQIENSAAVQKAITYYEEQMNQKIHMPTETLQELLDLHRTCEREAIEVFMKNSFKDVDQKFQEELGAQLEAKRDAFVKKNMDMSSAHCSDLLEGLFAHLEEEVKQGTFYKPGGYYLFLQRKQELEKKYIQTPGKGLQAEVMLRKYFESKEDLADTLLKMDQSLTEKEKQIEMERIKAEAAEAANRALAEMQKKHEMLMEQKEQSYQEHMKQLTEKMEQERKELMAEQQRIISLKLQEQERLLKQGFQNESLQLRQEIEKIKNMPPPRSCTIL

Target ORF information:

RefSeq Version	XM_030252421.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus guanylate binding protein 2b (Gbp2b), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_030252421.1

ORF Insert Sequence:

ATGGCCTCAG AAATCCACAT GAAAGGCCCA GTGTGCCTCA TCAAGAACTC CGGTGAGCAG 
TTGGAGGTCT ACCAGGAAGC ACTGGACATC CTGTCTGCTA TCCAAAATCC TGTGGTGGTC 
GTAGCAATAG TGGGCTTCTA CCACACAGGC AAATCCTATC TGATGAATAA GCTGGCTGGA 
AAGCAGAAGG GCTTCTCCCT GGGCTCCACT GTGCAGTCTC ACACAAAGGG CATCTGGATG 
TGGTGCATGC CTCATCCCGA GAAGCCAGAA CATACCCTGG TTCTGCTTGA CACTGAGGGC 
CTGAAAGACA TGCAGAAGGG TGACAACCAG AATGACTGTT GGATCTTTGC TTTGGCAGTC 
CTCCTCAGCA GCACCTTCAT CTACAACAGC ATAGGAACCA TCAACCAGCA GGCCATGGAC 
CAGCTGCACT ATGTGACAGA ACTGACTGAT CTCATCAAAT CAAAGTCATC ACCTGATCAG 
AGTGATGTAG ACAACTCAGC TAACTTTGTG GGCTTTTTTC CTATCTTTGT GTGGACTCTG 
AGGGATTTCT CCCTGGATCT GGAATTTGAT GGAGAATCCA TCACTCCTGA TGAGTACCTG 
GAGACTTCAC TGGCTCTGAG AAAAGGAACT GATGAGAACA CTAAAAAATT TAATATGCCT 
CGCCTGTGTA TCAGGAAGTT CTTCCCAAAG AGGAAGTGCT TCATCTTTGA CAGGCCTGGA 
GACAGGAAGC AACTTTCCAA ACTAGAGTGG ATACAGGAGG ACCAGCTGAA TAAAGAATTT 
GTAGAACAAG TTGCAGAATT CACCTCATAC ATCTTCAGCT ATTCTGGTGT CAAGACTCTA 
TCTGGAGGCA TCACAGTCAA TGGGCCACGT CTAAAAAGCC TGGTGCAGAC CTATGTCAGT 
GCCATCTGCA GTGGAGAACT ACCCTGTATG GAGAACGCAG TCCTGACTTT GGCCCAGATA 
GAGAACTCAG CAGCAGTGCA AAAGGCCATC ACCTACTACG AAGAACAGAT GAATCAGAAG 
ATCCACATGC CCACAGAAAC CCTCCAGGAG CTCCTGGATC TGCACAGGAC CTGTGAGAGG 
GAGGCCATTG AGGTCTTCAT GAAGAATTCT TTCAAGGATG TAGACCAGAA GTTCCAGGAA 
GAATTAGGGG CCCAGCTGGA AGCCAAACGA GATGCCTTTG TTAAGAAGAA CATGGACATG 
TCATCTGCTC ATTGCTCAGA CTTACTGGAG GGCCTCTTTG CTCATCTGGA AGAAGAAGTG 
AAGCAGGGGA CATTTTATAA ACCAGGAGGC TACTACCTTT TTCTTCAAAG GAAACAAGAG 
CTGGAGAAAA AGTATATCCA GACTCCTGGA AAGGGACTCC AGGCTGAAGT GATGCTGAGA 
AAATACTTTG AATCCAAGGA GGATTTGGCT GATACACTTC TAAAGATGGA CCAGTCACTC 
ACAGAAAAGG AAAAGCAGAT TGAAATGGAA CGTATAAAAG CAGAAGCCGC AGAAGCAGCA 
AATAGAGCAT TGGCAGAAAT GCAAAAGAAG CATGAGATGC TGATGGAACA GAAGGAACAG 
AGTTATCAAG AGCACATGAA ACAGCTGACT GAGAAGATGG AGCAGGAACG GAAAGAGTTA 
ATGGCAGAGC AACAAAGAAT CATATCCCTT AAACTTCAGG AACAGGAAAG ACTTCTCAAG 
CAAGGATTCC AGAATGAGAG CTTGCAACTA CGTCAAGAGA TAGAGAAAAT CAAGAACATG 
CCTCCACCTC GATCATGCAC CATACTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA.
BMC immunology17(1)25(2016 08)
Liu X,Jiao Y,Cao Y,Deng N,Ma Y,Hasty KA,Kang A,Chen H,Stuart JM,Gu W

Guanylate binding proteins enable rapid activation of canonical and noncanonical inflammasomes in Chlamydia-infected macrophages.
Infection and immunity83(12)4740-9(2015 Dec)
Finethy R,Jorgensen I,Haldar AK,de Zoete MR,Strowig T,Flavell RA,Yamamoto M,Nagarajan UM,Miao EA,Coers J

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Gbp2b cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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