Fkbp7 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Fkbp7
Entrez Gene ID	14231
Full Name	FK506 binding protein 7
Synonyms	23kDa,FKBP-7,FKBP23
General protein information	Preferred Names FK506 binding protein 7 Names peptidyl-prolyl cis-trans isomerase FKBP7 23 kDa FK506-binding protein 23 kDa FKBP FKBP-23 PPIase FKBP7 rotamase
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 2 Map Location: 2 C3\|2 45.09 cM

mRNA and Protein(s)

mRNA	Protein	Name
XM_006498749.2	XP_006498812.1	peptidyl-prolyl cis-trans isomerase FKBP7 isoform X1
NM_010222.2	NP_034352.1	peptidyl-prolyl cis-trans isomerase FKBP7 isoform 1 precursor
NM_001355080.1	NP_001342009.1	peptidyl-prolyl cis-trans isomerase FKBP7 isoform 3
NM_001355079.1	NP_001342008.1	peptidyl-prolyl cis-trans isomerase FKBP7 isoform 2 precursor

Pathways from BioSystems

Homologies

Xenopus tropicalis (tropical clawed frog)	fkbp7	NP_001107676.1
Homo sapiens (human)	FKBP7	NP_851939.1
Pan troglodytes (chimpanzee)	FKBP7	XP_515942.3
	FKBP7	XP_001098893.2
Rattus norvegicus (Norway rat)	Fkbp7	NP_001099955.2
Danio rerio (zebrafish)	fkbp7	NP_001004506.1
Canis lupus familiaris (dog)	FKBP7	XP_545546.1
Bos taurus (cattle)	FKBP7	NP_001093800.1
Mus musculus (house mouse)	Fkbp7	NP_034352.1
Gallus gallus (chicken)	FKBP7	XP_421981.4

Gene Ontology
Bibliography

Related articles in PubMed

Mouse FKBP23 mediates conformer-specific functions of BiP by catalyzing Pro117 cis/trans isomerization.
Feng M, Gu C, Ma S, Wang Y, Liu H, Han R, Gao J, Long Y, Mi H
Biochemical and biophysical research communications408(4)537-40(2011 May)

The binding of FKBP23 to BiP modulates BiP's ATPase activity with its PPIase activity.
Wang Y, Han R, Wu D, Li J, Chen C, Ma H, Mi H
Biochemical and biophysical research communications354(1)315-20(2007 Mar)

Binding of FKBP23 to BiP in ER shown by gel filtration chromatography.
Chen C, Ma H, Wang Y, Mi H
Zeitschrift fur Naturforschung. C, Journal of biosciences62(1-2)133-7(2007 Jan-Feb)

A neurogenomics approach to gene expression analysis in the developing brain.
Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T
Brain research. Molecular brain research132(2)116-27(2004 Dec)

The mouse FKBP23 binds to BiP in ER and the binding of C-terminal domain is interrelated with Ca2+ concentration.
Zhang X, Wang Y, Li H, Zhang W, Wu D, Mi H
FEBS letters559(1-3)57-60(2004 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

FKBP23 is demonstrated to mediate functions of BiP by catalyzing the Pro(117)cis/trans conformational interconversion in the ATPase domain of BiP.
Title: Mouse FKBP23 mediates conformer-specific functions of BiP by catalyzing Pro117 cis/trans isomerization.

In this study, we demonstrate the ability of mFKBP23 to modulate the ATPase activity of BiP, and that the bound mFKBP23, but not the free mFKBP23, can suppress the ATPase activity of mBiP through its PPIase activity.
Title: The binding of FKBP23 to BiP modulates BiP's ATPase activity with its PPIase activity.

binds to Grp78 (Bip) in endoplasmic reticulum.
Title: Binding of FKBP23 to BiP in ER shown by gel filtration chromatography.

mFKBP23 binds to immunoglobulin binding protein (mBiP,Hsp70); the binding of the C-terminus is Ca(2+)-dependent and the switch point is between 2 and 3 mM, no binding being detected at high concentration of calcium
Title: The mouse FKBP23 binds to BiP in ER and the binding of C-terminal domain is interrelated with Ca2+ concentration.

The following Fkbp7 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Fkbp7 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu30015	NM_001355079.1 Latest version!	Mus musculus FK506 binding protein 7 (Fkbp7), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OMu30015	XM_006498749.2 Latest version!	Mus musculus FK506 binding protein 7 (Fkbp7), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OMu05780	NM_010222.2 Latest version!	Mus musculus FK506 binding protein 7 (Fkbp7), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00
OMu67751	NM_001355080.1 Latest version!	Mus musculus FK506 binding protein 7 (Fkbp7), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Fkbp7 ( NM_001355079.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001342008.1 Mus musculus FK506 binding protein 7 (Fkbp7), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu30015
Clone ID Related Accession (Same CDS sequence)	XM_006498749.2 , NM_001355079.1
Accession Version	NM_001355079.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 654bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-22
Organism	Mus musculus(house mouse)
Product	peptidyl-prolyl cis-trans isomerase FKBP7 isoform 2 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL928867.9 and AI182368.1. On Sep 7, 2017 this sequence version replaced XM_006498749.2. Transcript Variant: This variant (2) uses an alternate in-frame splice junction compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is 1 aa shorter compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AI182368.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164133, SAMN01164137 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAATCTCC TATTCAGACT AGCAGTTTTC CTTAGCCTGT GGTGTTGTTC CGATGCTCAG 
GGACAAACAA AAGAAGAAAG CACTGAGGAA GTGAAAATAG AAGTTTTGCA CCGTCCAGAA 
AACTGCTCCA AAACAAGCAG GAAAGGAGAC TTGCTAAATG CCCATTACGA TGGCTACTTG 
GCTAAAGACG GCTCCAAATT CTACTGCAGC CGGACACAAG ATGAAGGCCA CCCCAAATGG 
TTTGTTCTTG GTGTCGGACA TGTCATAAAG GGGCTGGACA TTGCTATGAT GGACATGTGC 
CCTGGGGAAA AGAGAAAGGT GATTATACCG CCTTCGTTTG CATATGGAAA AGAAGGCTAC 
GAAGGCAAGA TTCCACCCAA TGCAACTCTG ATGTTTGAGA TTGAACTTTA TGCTGTGACC 
AAAGGACCAA GGAGCATTGA AACATTTAAG CAAATAGACA CGGATAATGA CCGGCAACTC 
TCCAAAGCTG AGATAGAGCT TTACTTACAG AAGGACTTTG AAAAAGATGC AAACCCCCGT 
GACAAGTCAT ATCAGAAGGC AGTTTTGGAA GATATCTTTA AGAAAAATGA CCACAATGGA 
GACGGCTTCA TTTCTCCTAA GGAATACAAT GTGCACCAAC ATGATGAGCT ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001342008.1
CDS	85..738
Translation	MNLLFRLAVFLSLWCCSDAQGQTKEESTEEVKIEVLHRPENCSKTSRKGDLLNAHYDGYLAKDGSKFYCSRTQDEGHPKWFVLGVGHVIKGLDIAMMDMCPGEKRKVIIPPSFAYGKEGYEGKIPPNATLMFEIELYAVTKGPRSIETFKQIDTDNDRQLSKAEIELYLQKDFEKDANPRDKSYQKAVLEDIFKKNDHNGDGFISPKEYNVHQHDEL

Target ORF information:

RefSeq Version	NM_001355079.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus FK506 binding protein 7 (Fkbp7), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001355079.1

ORF Insert Sequence:

ATGAATCTCC TATTCAGACT AGCAGTTTTC CTTAGCCTGT GGTGTTGTTC CGATGCTCAG 
GGACAAACAA AAGAAGAAAG CACTGAGGAA GTGAAAATAG AAGTTTTGCA CCGTCCAGAA 
AACTGCTCCA AAACAAGCAG GAAAGGAGAC TTGCTAAATG CCCATTACGA TGGCTACTTG 
GCTAAAGACG GCTCCAAATT CTACTGCAGC CGGACACAAG ATGAAGGCCA CCCCAAATGG 
TTTGTTCTTG GTGTCGGACA TGTCATAAAG GGGCTGGACA TTGCTATGAT GGACATGTGC 
CCTGGGGAAA AGAGAAAGGT GATTATACCG CCTTCGTTTG CATATGGAAA AGAAGGCTAC 
GAAGGCAAGA TTCCACCCAA TGCAACTCTG ATGTTTGAGA TTGAACTTTA TGCTGTGACC 
AAAGGACCAA GGAGCATTGA AACATTTAAG CAAATAGACA CGGATAATGA CCGGCAACTC 
TCCAAAGCTG AGATAGAGCT TTACTTACAG AAGGACTTTG AAAAAGATGC AAACCCCCGT 
GACAAGTCAT ATCAGAAGGC AGTTTTGGAA GATATCTTTA AGAAAAATGA CCACAATGGA 
GACGGCTTCA TTTCTCCTAA GGAATACAAT GTGCACCAAC ATGATGAGCT ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Fkbp7 ( XM_006498749.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006498812.1 Mus musculus FK506 binding protein 7 (Fkbp7), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu30015
Clone ID Related Accession (Same CDS sequence)	XM_006498749.2 , NM_001355079.1
Accession Version	XM_006498749.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 654bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(House mouse)
Product	peptidyl-prolyl cis-trans isomerase FKBP7 isoform X1
Comment	MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000068.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006498749.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAATCTCC TATTCAGACT AGCAGTTTTC CTTAGCCTGT GGTGTTGTTC CGATGCTCAG 
GGACAAACAA AAGAAGAAAG CACTGAGGAA GTGAAAATAG AAGTTTTGCA CCGTCCAGAA 
AACTGCTCCA AAACAAGCAG GAAAGGAGAC TTGCTAAATG CCCATTACGA TGGCTACTTG 
GCTAAAGACG GCTCCAAATT CTACTGCAGC CGGACACAAG ATGAAGGCCA CCCCAAATGG 
TTTGTTCTTG GTGTCGGACA TGTCATAAAG GGGCTGGACA TTGCTATGAT GGACATGTGC 
CCTGGGGAAA AGAGAAAGGT GATTATACCG CCTTCGTTTG CATATGGAAA AGAAGGCTAC 
GAAGGCAAGA TTCCACCCAA TGCAACTCTG ATGTTTGAGA TTGAACTTTA TGCTGTGACC 
AAAGGACCAA GGAGCATTGA AACATTTAAG CAAATAGACA CGGATAATGA CCGGCAACTC 
TCCAAAGCTG AGATAGAGCT TTACTTACAG AAGGACTTTG AAAAAGATGC AAACCCCCGT 
GACAAGTCAT ATCAGAAGGC AGTTTTGGAA GATATCTTTA AGAAAAATGA CCACAATGGA 
GACGGCTTCA TTTCTCCTAA GGAATACAAT GTGCACCAAC ATGATGAGCT ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006498812.1
CDS	126..779
Translation	MNLLFRLAVFLSLWCCSDAQGQTKEESTEEVKIEVLHRPENCSKTSRKGDLLNAHYDGYLAKDGSKFYCSRTQDEGHPKWFVLGVGHVIKGLDIAMMDMCPGEKRKVIIPPSFAYGKEGYEGKIPPNATLMFEIELYAVTKGPRSIETFKQIDTDNDRQLSKAEIELYLQKDFEKDANPRDKSYQKAVLEDIFKKNDHNGDGFISPKEYNVHQHDEL

Target ORF information:

RefSeq Version	XM_006498749.2
Organism	Mus musculus(House mouse)
Definition	Mus musculus FK506 binding protein 7 (Fkbp7), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006498749.2

ORF Insert Sequence:

ATGAATCTCC TATTCAGACT AGCAGTTTTC CTTAGCCTGT GGTGTTGTTC CGATGCTCAG 
GGACAAACAA AAGAAGAAAG CACTGAGGAA GTGAAAATAG AAGTTTTGCA CCGTCCAGAA 
AACTGCTCCA AAACAAGCAG GAAAGGAGAC TTGCTAAATG CCCATTACGA TGGCTACTTG 
GCTAAAGACG GCTCCAAATT CTACTGCAGC CGGACACAAG ATGAAGGCCA CCCCAAATGG 
TTTGTTCTTG GTGTCGGACA TGTCATAAAG GGGCTGGACA TTGCTATGAT GGACATGTGC 
CCTGGGGAAA AGAGAAAGGT GATTATACCG CCTTCGTTTG CATATGGAAA AGAAGGCTAC 
GAAGGCAAGA TTCCACCCAA TGCAACTCTG ATGTTTGAGA TTGAACTTTA TGCTGTGACC 
AAAGGACCAA GGAGCATTGA AACATTTAAG CAAATAGACA CGGATAATGA CCGGCAACTC 
TCCAAAGCTG AGATAGAGCT TTACTTACAG AAGGACTTTG AAAAAGATGC AAACCCCCGT 
GACAAGTCAT ATCAGAAGGC AGTTTTGGAA GATATCTTTA AGAAAAATGA CCACAATGGA 
GACGGCTTCA TTTCTCCTAA GGAATACAAT GTGCACCAAC ATGATGAGCT ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Fkbp7 ( NM_010222.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_034352.1 Mus musculus FK506 binding protein 7 (Fkbp7), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu05780
Clone ID Related Accession (Same CDS sequence)	NM_010222.2
Accession Version	NM_010222.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 657bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Mus musculus(house mouse)
Product	peptidyl-prolyl cis-trans isomerase FKBP7 isoform 1 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL928867.9. On Jun 27, 2009 this sequence version replaced NM_010222.1. Transcript Variant: This variant (1) represents the longest isoform (1). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AF040252.1, BC032961.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849380, SAMN01164131 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAATCTCC TATTCAGACT AGCAGTTTTC CTTAGCCTGT GGTGTTGTTC CGATGCTCAG 
GGACAAACAA AAGAAGAAAG CACTGAGGAA GTGAAAATAG AAGTTTTGCA CCGTCCAGAA 
AACTGCTCCA AAACAAGCAG GAAAGGAGAC TTGCTAAATG CCCATTACGA TGGCTACTTG 
GCTAAAGACG GCTCCAAATT CTACTGCAGC CGGACACAAG ATGAAGGCCA CCCCAAATGG 
TTTGTTCTTG GTGTCGGACA TGTCATAAAG GGGCTGGACA TTGCTATGAT GGACATGTGC 
CCTGGGGAAA AGAGAAAGGT GATTATACCG CCTTCGTTTG CATATGGAAA AGAAGGCTAC 
GCAGAAGGCA AGATTCCACC CAATGCAACT CTGATGTTTG AGATTGAACT TTATGCTGTG 
ACCAAAGGAC CAAGGAGCAT TGAAACATTT AAGCAAATAG ACACGGATAA TGACCGGCAA 
CTCTCCAAAG CTGAGATAGA GCTTTACTTA CAGAAGGACT TTGAAAAAGA TGCAAACCCC 
CGTGACAAGT CATATCAGAA GGCAGTTTTG GAAGATATCT TTAAGAAAAA TGACCACAAT 
GGAGACGGCT TCATTTCTCC TAAGGAATAC AATGTGCACC AACATGATGA GCTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_034352.1
CDS	85..741
Translation	MNLLFRLAVFLSLWCCSDAQGQTKEESTEEVKIEVLHRPENCSKTSRKGDLLNAHYDGYLAKDGSKFYCSRTQDEGHPKWFVLGVGHVIKGLDIAMMDMCPGEKRKVIIPPSFAYGKEGYAEGKIPPNATLMFEIELYAVTKGPRSIETFKQIDTDNDRQLSKAEIELYLQKDFEKDANPRDKSYQKAVLEDIFKKNDHNGDGFISPKEYNVHQHDEL

Target ORF information:

RefSeq Version	NM_010222.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus FK506 binding protein 7 (Fkbp7), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_010222.2

ORF Insert Sequence:

ATGAATCTCC TATTCAGACT AGCAGTTTTC CTTAGCCTGT GGTGTTGTTC CGATGCTCAG 
GGACAAACAA AAGAAGAAAG CACTGAGGAA GTGAAAATAG AAGTTTTGCA CCGTCCAGAA 
AACTGCTCCA AAACAAGCAG GAAAGGAGAC TTGCTAAATG CCCATTACGA TGGCTACTTG 
GCTAAAGACG GCTCCAAATT CTACTGCAGC CGGACACAAG ATGAAGGCCA CCCCAAATGG 
TTTGTTCTTG GTGTCGGACA TGTCATAAAG GGGCTGGACA TTGCTATGAT GGACATGTGC 
CCTGGGGAAA AGAGAAAGGT GATTATACCG CCTTCGTTTG CATATGGAAA AGAAGGCTAC 
GCAGAAGGCA AGATTCCACC CAATGCAACT CTGATGTTTG AGATTGAACT TTATGCTGTG 
ACCAAAGGAC CAAGGAGCAT TGAAACATTT AAGCAAATAG ACACGGATAA TGACCGGCAA 
CTCTCCAAAG CTGAGATAGA GCTTTACTTA CAGAAGGACT TTGAAAAAGA TGCAAACCCC 
CGTGACAAGT CATATCAGAA GGCAGTTTTG GAAGATATCT TTAAGAAAAA TGACCACAAT 
GGAGACGGCT TCATTTCTCC TAAGGAATAC AATGTGCACC AACATGATGA GCTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Fkbp7 ( NM_001355080.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001342009.1 Mus musculus FK506 binding protein 7 (Fkbp7), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OMu67751
Clone ID Related Accession (Same CDS sequence)	NM_001355080.1
Accession Version	NM_001355080.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 333bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-22
Organism	Mus musculus(house mouse)
Product	peptidyl-prolyl cis-trans isomerase FKBP7 isoform 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL928867.9. On Sep 13, 2017 this sequence version replaced XR_374406.3. Transcript Variant: This variant (3) contains an alternate exon compared to variant 1. The resulting isoform (3) has a shorter and distinct N-terminus compared to isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN00849384, SAMN01164131 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTGGCTTT CTAGTGCTTT GATTAACCAT CTCTGTGCAG AAGGCAAGAT TCCACCCAAT 
GCAACTCTGA TGTTTGAGAT TGAACTTTAT GCTGTGACCA AAGGACCAAG GAGCATTGAA 
ACATTTAAGC AAATAGACAC GGATAATGAC CGGCAACTCT CCAAAGCTGA GATAGAGCTT 
TACTTACAGA AGGACTTTGA AAAAGATGCA AACCCCCGTG ACAAGTCATA TCAGAAGGCA 
GTTTTGGAAG ATATCTTTAA GAAAAATGAC CACAATGGAG ACGGCTTCAT TTCTCCTAAG 
GAATACAATG TGCACCAACA TGATGAGCTA TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001342009.1
CDS	525..857
Translation	MWLSSALINHLCAEGKIPPNATLMFEIELYAVTKGPRSIETFKQIDTDNDRQLSKAEIELYLQKDFEKDANPRDKSYQKAVLEDIFKKNDHNGDGFISPKEYNVHQHDEL

Target ORF information:

RefSeq Version	NM_001355080.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus FK506 binding protein 7 (Fkbp7), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001355080.1

ORF Insert Sequence:

ATGTGGCTTT CTAGTGCTTT GATTAACCAT CTCTGTGCAG AAGGCAAGAT TCCACCCAAT 
GCAACTCTGA TGTTTGAGAT TGAACTTTAT GCTGTGACCA AAGGACCAAG GAGCATTGAA 
ACATTTAAGC AAATAGACAC GGATAATGAC CGGCAACTCT CCAAAGCTGA GATAGAGCTT 
TACTTACAGA AGGACTTTGA AAAAGATGCA AACCCCCGTG ACAAGTCATA TCAGAAGGCA 
GTTTTGGAAG ATATCTTTAA GAAAAATGAC CACAATGGAG ACGGCTTCAT TTCTCCTAAG 
GAATACAATG TGCACCAACA TGATGAGCTA TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Mouse FKBP23 mediates conformer-specific functions of BiP by catalyzing Pro117 cis/trans isomerization.
Biochemical and biophysical research communications408(4)537-40(2011 May)
Feng M,Gu C,Ma S,Wang Y,Liu H,Han R,Gao J,Long Y,Mi H

The binding of FKBP23 to BiP modulates BiP's ATPase activity with its PPIase activity.
Biochemical and biophysical research communications354(1)315-20(2007 Mar)
Wang Y,Han R,Wu D,Li J,Chen C,Ma H,Mi H

Binding of FKBP23 to BiP in ER shown by gel filtration chromatography.
Zeitschrift fur Naturforschung. C, Journal of biosciences62(1-2)133-7(2007 Jan-Feb)
Chen C,Ma H,Wang Y,Mi H

A neurogenomics approach to gene expression analysis in the developing brain.
Brain research. Molecular brain research132(2)116-27(2004 Dec)
Jensen P,Magdaleno S,Lehman KM,Rice DS,Lavallie ER,Collins-Racie L,McCoy JM,Curran T

The mouse FKBP23 binds to BiP in ER and the binding of C-terminal domain is interrelated with Ca2+ concentration.
FEBS letters559(1-3)57-60(2004 Feb)
Zhang X,Wang Y,Li H,Zhang W,Wu D,Mi H

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Fkbp7 cDNA ORF clone, Mus musculus(house mouse)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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