F2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	F2
Entrez Gene ID	14061
Full Name	coagulation factor II
Synonyms	Cf-2,Cf2,FII
General protein information	Preferred Names coagulation factor II Names prothrombin thrombin
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 2 Map Location: 2 E1\|2 50.63 cM
Summary	This gene encodes a vitamin K-dependent glycoprotein coagulation factor that plays an important role in the process of blood coagulation and hemostasis. The encoded protein is an inactive zymogen that undergoes enzymatic cleavage by the coagulation factor Xa to form an active serine protease that converts soluble fibrinogen to insoluble fibrin clot. Most of the mice lacking the encoded protein die at an embryonic stage due to defects in yolk sac vasculature, while the rare nenonates succumb to hemorrhage on the first postnatal day. [provided by RefSeq, Apr 2015].

mRNA and Protein(s)

mRNA	Protein	Name
NM_010168.3	NP_034298.1	prothrombin preproprotein
XM_011239288.1	XP_011237590.1	prothrombin isoform X1
XM_011239288.2	XP_011237590.1	prothrombin isoform X1
XM_030247399.1	XP_030103259.1	prothrombin isoform X1

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	F2	NP_075213.2
Danio rerio (zebrafish)	f2	NP_998555.1
Gallus gallus (chicken)	F2	NP_989936.1
Homo sapiens (human)	F2	NP_000497.1
	F2	NP_001098055.1
Canis lupus familiaris (dog)	F2	XP_003639742.1
Bos taurus (cattle)	F2	NP_776302.1
Xenopus tropicalis (tropical clawed frog)	f2	NP_001015797.1
Pan troglodytes (chimpanzee)	F2	XP_001165233.1
Mus musculus (house mouse)	F2	NP_034298.1

Gene Ontology
Bibliography

Related articles in PubMed

VKOR paralog VKORC1L1 supports vitamin K-dependent protein carboxylation in vivo.
Lacombe J, Rishavy MA, Berkner KL, Ferron M
JCI insight3(1)(2018 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Platelet derived microparticles formed in sepsis are a potent inducer of thrombin generation via phosphatidylserine exposure, and activation of both the intrinsic and extrinsic pathway of coagulation.
Title: Platelet-derived microparticles regulates thrombin generation via phophatidylserine in abdominal sepsis.

These findings imply that a thrombin-pericyte interaction in the brain could be a significant mechanism responsible for blood-brain barrier dysfunction under obesity-associated diabetic conditions and thus could represent a therapeutic target for central nervous system complications of diabetes.
Title: Contribution of thrombin-reactive brain pericytes to blood-brain barrier dysfunction in an in vivo mouse model of obesity-associated diabetes and an in vitro rat model.

mutations were introduced into the endogenous fII gene, resulting in expression of prothrombin carrying 3 amino acid substitutions (R157A, R268A, and K281A) to limit activation events to yield only fIIa(Meizothrombin) Homozygous fII(MZ) mice are viable, express fII levels comparable with fII(Wild type) mice, and have reproductive success.
Title: Limiting prothrombin activation to meizothrombin is compatible with survival but significantly alters hemostasis in mice.

Biglycan plays a protective role during the progression of atherosclerosis in ApoE-deficient mice by inhibiting thrombin generation.
Title: Loss of Biglycan Enhances Thrombin Generation in Apolipoprotein E-Deficient Mice: Implications for Inflammation and Atherosclerosis.

Observations illustrate the role of thrombin as a pleiotropic atherogenic molecule under conditions of hypercholesterolemia and suggest the utility of its inhibition with locally acting antithrombin nanoparticle therapeutics.
Title: Inhibition of Thrombin With PPACK-Nanoparticles Restores Disrupted Endothelial Barriers and Attenuates Thrombotic Risk in Experimental Atherosclerosis.

The following F2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the F2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu16293	NM_010168.3 Latest version!	Mus musculus coagulation factor II (F2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$363.30 $519.00
OMu67703	XM_030247399.1 Latest version!	Mus musculus coagulation factor II (F2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
OMu67703	XM_011239288.2 Latest version!	Mus musculus coagulation factor II (F2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
View Old Accession Versions >>
OMu67703	XM_011239288.1	Mus musculus coagulation factor II (F2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

F2 ( XM_011239288.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011237590.1 Mus musculus coagulation factor II (F2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu67703
Clone ID Related Accession (Same CDS sequence)	XM_011239288.1 , XM_011239288.2 , XM_030247399.1
Accession Version	XM_011239288.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1743bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	prothrombin isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000068.7) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCGCACG TCCGCGGCCT GGGCCTCCCT GGCTGCTTGG CTCTGGCTGC CCTGGTTAGC 
CTGGTACACA GCCAGCATGT GTTCCTGGCG CCTCAGCAAG CACTATCGCT GCTCCAGCGG 
GTCCGCAGAG CCAACAGTGG CTTCCTGGAG GAGCTCCGAA AGGGCAACCT AGAGCGTGAG 
TGCGTGGAAG AGCAGTGCAG CTATGAGGAG GCCTTTGAGG CCCTGGAGTC TCCCCAAGAC 
ACAGACGTGT TCTGGGCCAA GTACACAGTG TGTGATTCAG TGAGGAAACC TCGAGAGACT 
TTCATGGACT GTCTGGAAGG TCGCTGTGCT ATGGATCTGG GTGTGAACTA CCTTGGGACT 
GTGAATGTCA CCCATACCGG TATCCAGTGC CAGCTGTGGC GGAGCCGCTA CCCCCACAAG 
CCTGAAATCA ACTCCACCAC CCATCCTGGG GCAGACCTGA AGGAGAACTT CTGCCGCAAT 
CCAGACAGCA GTACCACGGG ACCCTGGTGC TACACCACAG ATCCTACTGT GCGCAGAGAG 
GAATGCAGTG TCCCTGTCTG TGGCCAGGAG GGCCGTACCA CTGTGGTGAT GACTCCTCGC 
TCTGGAGGTT CCAAGGACAA TCTGTCACCT CCACTGGGAC AGTGCCTCAC TGAGCGTGGC 
CGACTATACC AGGGGAATTT GGCTGTGACA ACACTTGGGT CCCCCTGCCT GCCCTGGAAC 
AGCTTACCAG CCAAGACCCT GAGCAAGTAC CAAGACTTCG ACCCCGAGGT GAAACTCGTG 
GAAAACTTCT GCCGCAACCC AGACTGGGAT GAGGAGGGCG CATGGTGCTA TGTTGCGGGG 
CAGCCTGGCG ACTTTGAATA CTGCAACCTC AACTACTGCG AGGAGGCGGT GGGAGAGGAG 
AACTATGATG TGGACGAGTC CATCGCGGGA CGCACCACCG ATGCGGAGTT CCACACCTTC 
TTCAATGAGA AGACCTTCGG CCTTGGGGAG GCAGACTGTG GCCTGCGGCC TTTGTTCGAG 
AAGAAGTCGT TGAAAGACAC AACCGAAAAG GAGCTTCTTG ACTCTTACAT AGACGGGCGC 
ATCGTGGAGG GCTGGGACGC TGAGAAGGGT ATCGCCCCCT GGCAGGTGAT GCTTTTTCGG 
AAGAGTCCCC AAGAGCTGCT GTGTGGGGCC AGCCTTATCA GTGACCGATG GGTCCTCACT 
GCTGCCCACT GCATTCTGTA CCCACCCTGG GACAAGAACT TCACTGAGAA TGACCTCCTG 
GTGCGCATTG GCAAGCATTC CCGAACCAGA TATGAGCGGA ATGTTGAAAA GATCTCCATG 
CTGGAAAAGA TCTACGTCCA CCCCAGATAT AACTGGCGGG AGAACCTAGA CCGCGATATC 
GCTCTGCTCA AGCTAAAGAA ACCTGTACCC TTCAGTGACT ATATTCACCC CGTGTGTTTG 
CCAGACAAGC AGACAGTAAC CAGCTTGCTC CGGGCTGGTT ATAAAGGGCG GGTGACAGGC 
TGGGGCAACC TTCGGGAGAC ATGGACAACC AACATCAATG AGATACAGCC CAGCGTCCTG 
CAGGTGGTGA ACCTGCCCAT TGTAGAGCGG CCAGTGTGCA AGGCCTCCAC CCGGATTCGA 
ATTACTGACA ACATGTTCTG TGCTGGCTTC AAGGTGAATG ACACCAAGCG AGGAGATGCT 
TGTGAAGGTG ACAGTGGAGG ACCTTTTGTC ATGAAGGCCT CAAGACTATG TTATGGAGAC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011237590.1
CDS	57..1799
Translation	MSHVRGLGLPGCLALAALVSLVHSQHVFLAPQQALSLLQRVRRANSGFLEELRKGNLERECVEEQCSYEEAFEALESPQDTDVFWAKYTVCDSVRKPRETFMDCLEGRCAMDLGVNYLGTVNVTHTGIQCQLWRSRYPHKPEINSTTHPGADLKENFCRNPDSSTTGPWCYTTDPTVRREECSVPVCGQEGRTTVVMTPRSGGSKDNLSPPLGQCLTERGRLYQGNLAVTTLGSPCLPWNSLPAKTLSKYQDFDPEVKLVENFCRNPDWDEEGAWCYVAGQPGDFEYCNLNYCEEAVGEENYDVDESIAGRTTDAEFHTFFNEKTFGLGEADCGLRPLFEKKSLKDTTEKELLDSYIDGRIVEGWDAEKGIAPWQVMLFRKSPQELLCGASLISDRWVLTAAHCILYPPWDKNFTENDLLVRIGKHSRTRYERNVEKISMLEKIYVHPRYNWRENLDRDIALLKLKKPVPFSDYIHPVCLPDKQTVTSLLRAGYKGRVTGWGNLRETWTTNINEIQPSVLQVVNLPIVERPVCKASTRIRITDNMFCAGFKVNDTKRGDACEGDSGGPFVMKASRLCYGD

Target ORF information:

RefSeq Version	XM_011239288.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus coagulation factor II (F2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011239288.1

ORF Insert Sequence:

ATGTCGCACG TCCGCGGCCT GGGCCTCCCT GGCTGCTTGG CTCTGGCTGC CCTGGTTAGC 
CTGGTACACA GCCAGCATGT GTTCCTGGCG CCTCAGCAAG CACTATCGCT GCTCCAGCGG 
GTCCGCAGAG CCAACAGTGG CTTCCTGGAG GAGCTCCGAA AGGGCAACCT AGAGCGTGAG 
TGCGTGGAAG AGCAGTGCAG CTATGAGGAG GCCTTTGAGG CCCTGGAGTC TCCCCAAGAC 
ACAGACGTGT TCTGGGCCAA GTACACAGTG TGTGATTCAG TGAGGAAACC TCGAGAGACT 
TTCATGGACT GTCTGGAAGG TCGCTGTGCT ATGGATCTGG GTGTGAACTA CCTTGGGACT 
GTGAATGTCA CCCATACCGG TATCCAGTGC CAGCTGTGGC GGAGCCGCTA CCCCCACAAG 
CCTGAAATCA ACTCCACCAC CCATCCTGGG GCAGACCTGA AGGAGAACTT CTGCCGCAAT 
CCAGACAGCA GTACCACGGG ACCCTGGTGC TACACCACAG ATCCTACTGT GCGCAGAGAG 
GAATGCAGTG TCCCTGTCTG TGGCCAGGAG GGCCGTACCA CTGTGGTGAT GACTCCTCGC 
TCTGGAGGTT CCAAGGACAA TCTGTCACCT CCACTGGGAC AGTGCCTCAC TGAGCGTGGC 
CGACTATACC AGGGGAATTT GGCTGTGACA ACACTTGGGT CCCCCTGCCT GCCCTGGAAC 
AGCTTACCAG CCAAGACCCT GAGCAAGTAC CAAGACTTCG ACCCCGAGGT GAAACTCGTG 
GAAAACTTCT GCCGCAACCC AGACTGGGAT GAGGAGGGCG CATGGTGCTA TGTTGCGGGG 
CAGCCTGGCG ACTTTGAATA CTGCAACCTC AACTACTGCG AGGAGGCGGT GGGAGAGGAG 
AACTATGATG TGGACGAGTC CATCGCGGGA CGCACCACCG ATGCGGAGTT CCACACCTTC 
TTCAATGAGA AGACCTTCGG CCTTGGGGAG GCAGACTGTG GCCTGCGGCC TTTGTTCGAG 
AAGAAGTCGT TGAAAGACAC AACCGAAAAG GAGCTTCTTG ACTCTTACAT AGACGGGCGC 
ATCGTGGAGG GCTGGGACGC TGAGAAGGGT ATCGCCCCCT GGCAGGTGAT GCTTTTTCGG 
AAGAGTCCCC AAGAGCTGCT GTGTGGGGCC AGCCTTATCA GTGACCGATG GGTCCTCACT 
GCTGCCCACT GCATTCTGTA CCCACCCTGG GACAAGAACT TCACTGAGAA TGACCTCCTG 
GTGCGCATTG GCAAGCATTC CCGAACCAGA TATGAGCGGA ATGTTGAAAA GATCTCCATG 
CTGGAAAAGA TCTACGTCCA CCCCAGATAT AACTGGCGGG AGAACCTAGA CCGCGATATC 
GCTCTGCTCA AGCTAAAGAA ACCTGTACCC TTCAGTGACT ATATTCACCC CGTGTGTTTG 
CCAGACAAGC AGACAGTAAC CAGCTTGCTC CGGGCTGGTT ATAAAGGGCG GGTGACAGGC 
TGGGGCAACC TTCGGGAGAC ATGGACAACC AACATCAATG AGATACAGCC CAGCGTCCTG 
CAGGTGGTGA ACCTGCCCAT TGTAGAGCGG CCAGTGTGCA AGGCCTCCAC CCGGATTCGA 
ATTACTGACA ACATGTTCTG TGCTGGCTTC AAGGTGAATG ACACCAAGCG AGGAGATGCT 
TGTGAAGGTG ACAGTGGAGG ACCTTTTGTC ATGAAGGCCT CAAGACTATG TTATGGAGAC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

F2 ( NM_010168.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_034298.1 Mus musculus coagulation factor II (F2), mRNA.

Price & Availability↑

CloneID	OMu16293
Clone ID Related Accession (Same CDS sequence)	NM_010168.3
Accession Version	NM_010168.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1857bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-04
Organism	Mus musculus(house mouse)
Product	prothrombin preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BY705183.1, AK167532.1 and X52308.1. On Apr 7, 2015 this sequence version replaced NM_010168.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: X52308.1, AK149367.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849386, SAMN01164134 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCGCACG TCCGCGGCCT GGGCCTCCCT GGCTGCTTGG CTCTGGCTGC CCTGGTTAGC 
CTGGTACACA GCCAGCATGT GTTCCTGGCG CCTCAGCAAG CACTATCGCT GCTCCAGCGG 
GTCCGCAGAG CCAACAGTGG CTTCCTGGAG GAGCTCCGAA AGGGCAACCT AGAGCGTGAG 
TGCGTGGAAG AGCAGTGCAG CTATGAGGAG GCCTTTGAGG CCCTGGAGTC TCCCCAAGAC 
ACAGACGTGT TCTGGGCCAA GTACACAGTG TGTGATTCAG TGAGGAAACC TCGAGAGACT 
TTCATGGACT GTCTGGAAGG TCGCTGTGCT ATGGATCTGG GTGTGAACTA CCTTGGGACT 
GTGAATGTCA CCCATACCGG TATCCAGTGC CAGCTGTGGC GGAGCCGCTA CCCCCACAAG 
CCTGAAATCA ACTCCACCAC CCATCCTGGG GCAGACCTGA AGGAGAACTT CTGCCGCAAT 
CCAGACAGCA GTACCACGGG ACCCTGGTGC TACACCACAG ATCCTACTGT GCGCAGAGAG 
GAATGCAGTG TCCCTGTCTG TGGCCAGGAG GGCCGTACCA CTGTGGTGAT GACTCCTCGC 
TCTGGAGGTT CCAAGGACAA TCTGTCACCT CCACTGGGAC AGTGCCTCAC TGAGCGTGGC 
CGACTATACC AGGGGAATTT GGCTGTGACA ACACTTGGGT CCCCCTGCCT GCCCTGGAAC 
AGCTTACCAG CCAAGACCCT GAGCAAGTAC CAAGACTTCG ACCCCGAGGT GAAACTCGTG 
GAAAACTTCT GCCGCAACCC AGACTGGGAT GAGGAGGGCG CATGGTGCTA TGTTGCGGGG 
CAGCCTGGCG ACTTTGAATA CTGCAACCTC AACTACTGCG AGGAGGCGGT GGGAGAGGAG 
AACTATGATG TGGACGAGTC CATCGCGGGA CGCACCACCG ATGCGGAGTT CCACACCTTC 
TTCAATGAGA AGACCTTCGG CCTTGGGGAG GCAGACTGTG GCCTGCGGCC TTTGTTCGAG 
AAGAAGTCGT TGAAAGACAC AACCGAAAAG GAGCTTCTTG ACTCTTACAT AGACGGGCGC 
ATCGTGGAGG GCTGGGACGC TGAGAAGGGT ATCGCCCCCT GGCAGGTGAT GCTTTTTCGG 
AAGAGTCCCC AAGAGCTGCT GTGTGGGGCC AGCCTTATCA GTGACCGATG GGTCCTCACT 
GCTGCCCACT GCATTCTGTA CCCACCCTGG GACAAGAACT TCACTGAGAA TGACCTCCTG 
GTGCGCATTG GCAAGCATTC CCGAACCAGA TATGAGCGGA ATGTTGAAAA GATCTCCATG 
CTGGAAAAGA TCTACGTCCA CCCCAGATAT AACTGGCGGG AGAACCTAGA CCGCGATATC 
GCTCTGCTCA AGCTAAAGAA ACCTGTACCC TTCAGTGACT ATATTCACCC CGTGTGTTTG 
CCAGACAAGC AGACAGTAAC CAGCTTGCTC CGGGCTGGTT ATAAAGGGCG GGTGACAGGC 
TGGGGCAACC TTCGGGAGAC ATGGACAACC AACATCAATG AGATACAGCC CAGCGTCCTG 
CAGGTGGTGA ACCTGCCCAT TGTAGAGCGG CCAGTGTGCA AGGCCTCCAC CCGGATTCGA 
ATTACTGACA ACATGTTCTG TGCTGGCTTC AAGGTGAATG ACACCAAGCG AGGAGATGCT 
TGTGAAGGTG ACAGTGGAGG ACCTTTTGTC ATGAAGAGCC CCTTTAACAA CCGCTGGTAT 
CAAATGGGTA TTGTCTCATG GGGTGAAGGA TGTGACCGGA AGGGGAAATA CGGCTTCTAC 
ACGCATGTGT TCCGTCTGAA AAGGTGGATA CAGAAAGTCA TTGATCAATT TGGATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_034298.1
CDS	62..1918
Translation	MSHVRGLGLPGCLALAALVSLVHSQHVFLAPQQALSLLQRVRRANSGFLEELRKGNLERECVEEQCSYEEAFEALESPQDTDVFWAKYTVCDSVRKPRETFMDCLEGRCAMDLGVNYLGTVNVTHTGIQCQLWRSRYPHKPEINSTTHPGADLKENFCRNPDSSTTGPWCYTTDPTVRREECSVPVCGQEGRTTVVMTPRSGGSKDNLSPPLGQCLTERGRLYQGNLAVTTLGSPCLPWNSLPAKTLSKYQDFDPEVKLVENFCRNPDWDEEGAWCYVAGQPGDFEYCNLNYCEEAVGEENYDVDESIAGRTTDAEFHTFFNEKTFGLGEADCGLRPLFEKKSLKDTTEKELLDSYIDGRIVEGWDAEKGIAPWQVMLFRKSPQELLCGASLISDRWVLTAAHCILYPPWDKNFTENDLLVRIGKHSRTRYERNVEKISMLEKIYVHPRYNWRENLDRDIALLKLKKPVPFSDYIHPVCLPDKQTVTSLLRAGYKGRVTGWGNLRETWTTNINEIQPSVLQVVNLPIVERPVCKASTRIRITDNMFCAGFKVNDTKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRKGKYGFYTHVFRLKRWIQKVIDQFG

Target ORF information:

RefSeq Version	NM_010168.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus coagulation factor II (F2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_010168.3

ORF Insert Sequence:

ATGTCGCACG TCCGCGGCCT GGGCCTCCCT GGCTGCTTGG CTCTGGCTGC CCTGGTTAGC 
CTGGTACACA GCCAGCATGT GTTCCTGGCG CCTCAGCAAG CACTATCGCT GCTCCAGCGG 
GTCCGCAGAG CCAACAGTGG CTTCCTGGAG GAGCTCCGAA AGGGCAACCT AGAGCGTGAG 
TGCGTGGAAG AGCAGTGCAG CTATGAGGAG GCCTTTGAGG CCCTGGAGTC TCCCCAAGAC 
ACAGACGTGT TCTGGGCCAA GTACACAGTG TGTGATTCAG TGAGGAAACC TCGAGAGACT 
TTCATGGACT GTCTGGAAGG TCGCTGTGCT ATGGATCTGG GTGTGAACTA CCTTGGGACT 
GTGAATGTCA CCCATACCGG TATCCAGTGC CAGCTGTGGC GGAGCCGCTA CCCCCACAAG 
CCTGAAATCA ACTCCACCAC CCATCCTGGG GCAGACCTGA AGGAGAACTT CTGCCGCAAT 
CCAGACAGCA GTACCACGGG ACCCTGGTGC TACACCACAG ATCCTACTGT GCGCAGAGAG 
GAATGCAGTG TCCCTGTCTG TGGCCAGGAG GGCCGTACCA CTGTGGTGAT GACTCCTCGC 
TCTGGAGGTT CCAAGGACAA TCTGTCACCT CCACTGGGAC AGTGCCTCAC TGAGCGTGGC 
CGACTATACC AGGGGAATTT GGCTGTGACA ACACTTGGGT CCCCCTGCCT GCCCTGGAAC 
AGCTTACCAG CCAAGACCCT GAGCAAGTAC CAAGACTTCG ACCCCGAGGT GAAACTCGTG 
GAAAACTTCT GCCGCAACCC AGACTGGGAT GAGGAGGGCG CATGGTGCTA TGTTGCGGGG 
CAGCCTGGCG ACTTTGAATA CTGCAACCTC AACTACTGCG AGGAGGCGGT GGGAGAGGAG 
AACTATGATG TGGACGAGTC CATCGCGGGA CGCACCACCG ATGCGGAGTT CCACACCTTC 
TTCAATGAGA AGACCTTCGG CCTTGGGGAG GCAGACTGTG GCCTGCGGCC TTTGTTCGAG 
AAGAAGTCGT TGAAAGACAC AACCGAAAAG GAGCTTCTTG ACTCTTACAT AGACGGGCGC 
ATCGTGGAGG GCTGGGACGC TGAGAAGGGT ATCGCCCCCT GGCAGGTGAT GCTTTTTCGG 
AAGAGTCCCC AAGAGCTGCT GTGTGGGGCC AGCCTTATCA GTGACCGATG GGTCCTCACT 
GCTGCCCACT GCATTCTGTA CCCACCCTGG GACAAGAACT TCACTGAGAA TGACCTCCTG 
GTGCGCATTG GCAAGCATTC CCGAACCAGA TATGAGCGGA ATGTTGAAAA GATCTCCATG 
CTGGAAAAGA TCTACGTCCA CCCCAGATAT AACTGGCGGG AGAACCTAGA CCGCGATATC 
GCTCTGCTCA AGCTAAAGAA ACCTGTACCC TTCAGTGACT ATATTCACCC CGTGTGTTTG 
CCAGACAAGC AGACAGTAAC CAGCTTGCTC CGGGCTGGTT ATAAAGGGCG GGTGACAGGC 
TGGGGCAACC TTCGGGAGAC ATGGACAACC AACATCAATG AGATACAGCC CAGCGTCCTG 
CAGGTGGTGA ACCTGCCCAT TGTAGAGCGG CCAGTGTGCA AGGCCTCCAC CCGGATTCGA 
ATTACTGACA ACATGTTCTG TGCTGGCTTC AAGGTGAATG ACACCAAGCG AGGAGATGCT 
TGTGAAGGTG ACAGTGGAGG ACCTTTTGTC ATGAAGAGCC CCTTTAACAA CCGCTGGTAT 
CAAATGGGTA TTGTCTCATG GGGTGAAGGA TGTGACCGGA AGGGGAAATA CGGCTTCTAC 
ACGCATGTGT TCCGTCTGAA AAGGTGGATA CAGAAAGTCA TTGATCAATT TGGATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

F2 ( XM_011239288.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011237590.1 Mus musculus coagulation factor II (F2), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu67703
Clone ID Related Accession (Same CDS sequence)	XM_011239288.1 , XM_011239288.2 , XM_030247399.1
Accession Version	XM_011239288.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1743bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	prothrombin isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000068.7) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_011239288.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCGCACG TCCGCGGCCT GGGCCTCCCT GGCTGCTTGG CTCTGGCTGC CCTGGTTAGC 
CTGGTACACA GCCAGCATGT GTTCCTGGCG CCTCAGCAAG CACTATCGCT GCTCCAGCGG 
GTCCGCAGAG CCAACAGTGG CTTCCTGGAG GAGCTCCGAA AGGGCAACCT AGAGCGTGAG 
TGCGTGGAAG AGCAGTGCAG CTATGAGGAG GCCTTTGAGG CCCTGGAGTC TCCCCAAGAC 
ACAGACGTGT TCTGGGCCAA GTACACAGTG TGTGATTCAG TGAGGAAACC TCGAGAGACT 
TTCATGGACT GTCTGGAAGG TCGCTGTGCT ATGGATCTGG GTGTGAACTA CCTTGGGACT 
GTGAATGTCA CCCATACCGG TATCCAGTGC CAGCTGTGGC GGAGCCGCTA CCCCCACAAG 
CCTGAAATCA ACTCCACCAC CCATCCTGGG GCAGACCTGA AGGAGAACTT CTGCCGCAAT 
CCAGACAGCA GTACCACGGG ACCCTGGTGC TACACCACAG ATCCTACTGT GCGCAGAGAG 
GAATGCAGTG TCCCTGTCTG TGGCCAGGAG GGCCGTACCA CTGTGGTGAT GACTCCTCGC 
TCTGGAGGTT CCAAGGACAA TCTGTCACCT CCACTGGGAC AGTGCCTCAC TGAGCGTGGC 
CGACTATACC AGGGGAATTT GGCTGTGACA ACACTTGGGT CCCCCTGCCT GCCCTGGAAC 
AGCTTACCAG CCAAGACCCT GAGCAAGTAC CAAGACTTCG ACCCCGAGGT GAAACTCGTG 
GAAAACTTCT GCCGCAACCC AGACTGGGAT GAGGAGGGCG CATGGTGCTA TGTTGCGGGG 
CAGCCTGGCG ACTTTGAATA CTGCAACCTC AACTACTGCG AGGAGGCGGT GGGAGAGGAG 
AACTATGATG TGGACGAGTC CATCGCGGGA CGCACCACCG ATGCGGAGTT CCACACCTTC 
TTCAATGAGA AGACCTTCGG CCTTGGGGAG GCAGACTGTG GCCTGCGGCC TTTGTTCGAG 
AAGAAGTCGT TGAAAGACAC AACCGAAAAG GAGCTTCTTG ACTCTTACAT AGACGGGCGC 
ATCGTGGAGG GCTGGGACGC TGAGAAGGGT ATCGCCCCCT GGCAGGTGAT GCTTTTTCGG 
AAGAGTCCCC AAGAGCTGCT GTGTGGGGCC AGCCTTATCA GTGACCGATG GGTCCTCACT 
GCTGCCCACT GCATTCTGTA CCCACCCTGG GACAAGAACT TCACTGAGAA TGACCTCCTG 
GTGCGCATTG GCAAGCATTC CCGAACCAGA TATGAGCGGA ATGTTGAAAA GATCTCCATG 
CTGGAAAAGA TCTACGTCCA CCCCAGATAT AACTGGCGGG AGAACCTAGA CCGCGATATC 
GCTCTGCTCA AGCTAAAGAA ACCTGTACCC TTCAGTGACT ATATTCACCC CGTGTGTTTG 
CCAGACAAGC AGACAGTAAC CAGCTTGCTC CGGGCTGGTT ATAAAGGGCG GGTGACAGGC 
TGGGGCAACC TTCGGGAGAC ATGGACAACC AACATCAATG AGATACAGCC CAGCGTCCTG 
CAGGTGGTGA ACCTGCCCAT TGTAGAGCGG CCAGTGTGCA AGGCCTCCAC CCGGATTCGA 
ATTACTGACA ACATGTTCTG TGCTGGCTTC AAGGTGAATG ACACCAAGCG AGGAGATGCT 
TGTGAAGGTG ACAGTGGAGG ACCTTTTGTC ATGAAGGCCT CAAGACTATG TTATGGAGAC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011237590.1
CDS	59..1801
Translation	MSHVRGLGLPGCLALAALVSLVHSQHVFLAPQQALSLLQRVRRANSGFLEELRKGNLERECVEEQCSYEEAFEALESPQDTDVFWAKYTVCDSVRKPRETFMDCLEGRCAMDLGVNYLGTVNVTHTGIQCQLWRSRYPHKPEINSTTHPGADLKENFCRNPDSSTTGPWCYTTDPTVRREECSVPVCGQEGRTTVVMTPRSGGSKDNLSPPLGQCLTERGRLYQGNLAVTTLGSPCLPWNSLPAKTLSKYQDFDPEVKLVENFCRNPDWDEEGAWCYVAGQPGDFEYCNLNYCEEAVGEENYDVDESIAGRTTDAEFHTFFNEKTFGLGEADCGLRPLFEKKSLKDTTEKELLDSYIDGRIVEGWDAEKGIAPWQVMLFRKSPQELLCGASLISDRWVLTAAHCILYPPWDKNFTENDLLVRIGKHSRTRYERNVEKISMLEKIYVHPRYNWRENLDRDIALLKLKKPVPFSDYIHPVCLPDKQTVTSLLRAGYKGRVTGWGNLRETWTTNINEIQPSVLQVVNLPIVERPVCKASTRIRITDNMFCAGFKVNDTKRGDACEGDSGGPFVMKASRLCYGD

Target ORF information:

RefSeq Version	XM_011239288.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus coagulation factor II (F2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011239288.2

ORF Insert Sequence:

ATGTCGCACG TCCGCGGCCT GGGCCTCCCT GGCTGCTTGG CTCTGGCTGC CCTGGTTAGC 
CTGGTACACA GCCAGCATGT GTTCCTGGCG CCTCAGCAAG CACTATCGCT GCTCCAGCGG 
GTCCGCAGAG CCAACAGTGG CTTCCTGGAG GAGCTCCGAA AGGGCAACCT AGAGCGTGAG 
TGCGTGGAAG AGCAGTGCAG CTATGAGGAG GCCTTTGAGG CCCTGGAGTC TCCCCAAGAC 
ACAGACGTGT TCTGGGCCAA GTACACAGTG TGTGATTCAG TGAGGAAACC TCGAGAGACT 
TTCATGGACT GTCTGGAAGG TCGCTGTGCT ATGGATCTGG GTGTGAACTA CCTTGGGACT 
GTGAATGTCA CCCATACCGG TATCCAGTGC CAGCTGTGGC GGAGCCGCTA CCCCCACAAG 
CCTGAAATCA ACTCCACCAC CCATCCTGGG GCAGACCTGA AGGAGAACTT CTGCCGCAAT 
CCAGACAGCA GTACCACGGG ACCCTGGTGC TACACCACAG ATCCTACTGT GCGCAGAGAG 
GAATGCAGTG TCCCTGTCTG TGGCCAGGAG GGCCGTACCA CTGTGGTGAT GACTCCTCGC 
TCTGGAGGTT CCAAGGACAA TCTGTCACCT CCACTGGGAC AGTGCCTCAC TGAGCGTGGC 
CGACTATACC AGGGGAATTT GGCTGTGACA ACACTTGGGT CCCCCTGCCT GCCCTGGAAC 
AGCTTACCAG CCAAGACCCT GAGCAAGTAC CAAGACTTCG ACCCCGAGGT GAAACTCGTG 
GAAAACTTCT GCCGCAACCC AGACTGGGAT GAGGAGGGCG CATGGTGCTA TGTTGCGGGG 
CAGCCTGGCG ACTTTGAATA CTGCAACCTC AACTACTGCG AGGAGGCGGT GGGAGAGGAG 
AACTATGATG TGGACGAGTC CATCGCGGGA CGCACCACCG ATGCGGAGTT CCACACCTTC 
TTCAATGAGA AGACCTTCGG CCTTGGGGAG GCAGACTGTG GCCTGCGGCC TTTGTTCGAG 
AAGAAGTCGT TGAAAGACAC AACCGAAAAG GAGCTTCTTG ACTCTTACAT AGACGGGCGC 
ATCGTGGAGG GCTGGGACGC TGAGAAGGGT ATCGCCCCCT GGCAGGTGAT GCTTTTTCGG 
AAGAGTCCCC AAGAGCTGCT GTGTGGGGCC AGCCTTATCA GTGACCGATG GGTCCTCACT 
GCTGCCCACT GCATTCTGTA CCCACCCTGG GACAAGAACT TCACTGAGAA TGACCTCCTG 
GTGCGCATTG GCAAGCATTC CCGAACCAGA TATGAGCGGA ATGTTGAAAA GATCTCCATG 
CTGGAAAAGA TCTACGTCCA CCCCAGATAT AACTGGCGGG AGAACCTAGA CCGCGATATC 
GCTCTGCTCA AGCTAAAGAA ACCTGTACCC TTCAGTGACT ATATTCACCC CGTGTGTTTG 
CCAGACAAGC AGACAGTAAC CAGCTTGCTC CGGGCTGGTT ATAAAGGGCG GGTGACAGGC 
TGGGGCAACC TTCGGGAGAC ATGGACAACC AACATCAATG AGATACAGCC CAGCGTCCTG 
CAGGTGGTGA ACCTGCCCAT TGTAGAGCGG CCAGTGTGCA AGGCCTCCAC CCGGATTCGA 
ATTACTGACA ACATGTTCTG TGCTGGCTTC AAGGTGAATG ACACCAAGCG AGGAGATGCT 
TGTGAAGGTG ACAGTGGAGG ACCTTTTGTC ATGAAGGCCT CAAGACTATG TTATGGAGAC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

F2 ( XM_030247399.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_030103259.1 Mus musculus coagulation factor II (F2), transcript variant X1, mRNA.

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CloneID	OMu67703
Clone ID Related Accession (Same CDS sequence)	XM_011239288.1 , XM_011239288.2 , XM_030247399.1
Accession Version	XM_030247399.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1743bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	prothrombin isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000068.7) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCGCACG TCCGCGGCCT GGGCCTCCCT GGCTGCTTGG CTCTGGCTGC CCTGGTTAGC 
CTGGTACACA GCCAGCATGT GTTCCTGGCG CCTCAGCAAG CACTATCGCT GCTCCAGCGG 
GTCCGCAGAG CCAACAGTGG CTTCCTGGAG GAGCTCCGAA AGGGCAACCT AGAGCGTGAG 
TGCGTGGAAG AGCAGTGCAG CTATGAGGAG GCCTTTGAGG CCCTGGAGTC TCCCCAAGAC 
ACAGACGTGT TCTGGGCCAA GTACACAGTG TGTGATTCAG TGAGGAAACC TCGAGAGACT 
TTCATGGACT GTCTGGAAGG TCGCTGTGCT ATGGATCTGG GTGTGAACTA CCTTGGGACT 
GTGAATGTCA CCCATACCGG TATCCAGTGC CAGCTGTGGC GGAGCCGCTA CCCCCACAAG 
CCTGAAATCA ACTCCACCAC CCATCCTGGG GCAGACCTGA AGGAGAACTT CTGCCGCAAT 
CCAGACAGCA GTACCACGGG ACCCTGGTGC TACACCACAG ATCCTACTGT GCGCAGAGAG 
GAATGCAGTG TCCCTGTCTG TGGCCAGGAG GGCCGTACCA CTGTGGTGAT GACTCCTCGC 
TCTGGAGGTT CCAAGGACAA TCTGTCACCT CCACTGGGAC AGTGCCTCAC TGAGCGTGGC 
CGACTATACC AGGGGAATTT GGCTGTGACA ACACTTGGGT CCCCCTGCCT GCCCTGGAAC 
AGCTTACCAG CCAAGACCCT GAGCAAGTAC CAAGACTTCG ACCCCGAGGT GAAACTCGTG 
GAAAACTTCT GCCGCAACCC AGACTGGGAT GAGGAGGGCG CATGGTGCTA TGTTGCGGGG 
CAGCCTGGCG ACTTTGAATA CTGCAACCTC AACTACTGCG AGGAGGCGGT GGGAGAGGAG 
AACTATGATG TGGACGAGTC CATCGCGGGA CGCACCACCG ATGCGGAGTT CCACACCTTC 
TTCAATGAGA AGACCTTCGG CCTTGGGGAG GCAGACTGTG GCCTGCGGCC TTTGTTCGAG 
AAGAAGTCGT TGAAAGACAC AACCGAAAAG GAGCTTCTTG ACTCTTACAT AGACGGGCGC 
ATCGTGGAGG GCTGGGACGC TGAGAAGGGT ATCGCCCCCT GGCAGGTGAT GCTTTTTCGG 
AAGAGTCCCC AAGAGCTGCT GTGTGGGGCC AGCCTTATCA GTGACCGATG GGTCCTCACT 
GCTGCCCACT GCATTCTGTA CCCACCCTGG GACAAGAACT TCACTGAGAA TGACCTCCTG 
GTGCGCATTG GCAAGCATTC CCGAACCAGA TATGAGCGGA ATGTTGAAAA GATCTCCATG 
CTGGAAAAGA TCTACGTCCA CCCCAGATAT AACTGGCGGG AGAACCTAGA CCGCGATATC 
GCTCTGCTCA AGCTAAAGAA ACCTGTACCC TTCAGTGACT ATATTCACCC CGTGTGTTTG 
CCAGACAAGC AGACAGTAAC CAGCTTGCTC CGGGCTGGTT ATAAAGGGCG GGTGACAGGC 
TGGGGCAACC TTCGGGAGAC ATGGACAACC AACATCAATG AGATACAGCC CAGCGTCCTG 
CAGGTGGTGA ACCTGCCCAT TGTAGAGCGG CCAGTGTGCA AGGCCTCCAC CCGGATTCGA 
ATTACTGACA ACATGTTCTG TGCTGGCTTC AAGGTGAATG ACACCAAGCG AGGAGATGCT 
TGTGAAGGTG ACAGTGGAGG ACCTTTTGTC ATGAAGGCCT CAAGACTATG TTATGGAGAC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_030103259.1
CDS	59..1801
Translation	MSHVRGLGLPGCLALAALVSLVHSQHVFLAPQQALSLLQRVRRANSGFLEELRKGNLERECVEEQCSYEEAFEALESPQDTDVFWAKYTVCDSVRKPRETFMDCLEGRCAMDLGVNYLGTVNVTHTGIQCQLWRSRYPHKPEINSTTHPGADLKENFCRNPDSSTTGPWCYTTDPTVRREECSVPVCGQEGRTTVVMTPRSGGSKDNLSPPLGQCLTERGRLYQGNLAVTTLGSPCLPWNSLPAKTLSKYQDFDPEVKLVENFCRNPDWDEEGAWCYVAGQPGDFEYCNLNYCEEAVGEENYDVDESIAGRTTDAEFHTFFNEKTFGLGEADCGLRPLFEKKSLKDTTEKELLDSYIDGRIVEGWDAEKGIAPWQVMLFRKSPQELLCGASLISDRWVLTAAHCILYPPWDKNFTENDLLVRIGKHSRTRYERNVEKISMLEKIYVHPRYNWRENLDRDIALLKLKKPVPFSDYIHPVCLPDKQTVTSLLRAGYKGRVTGWGNLRETWTTNINEIQPSVLQVVNLPIVERPVCKASTRIRITDNMFCAGFKVNDTKRGDACEGDSGGPFVMKASRLCYGD

Target ORF information:

RefSeq Version	XM_030247399.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus coagulation factor II (F2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_030247399.1

ORF Insert Sequence:

ATGTCGCACG TCCGCGGCCT GGGCCTCCCT GGCTGCTTGG CTCTGGCTGC CCTGGTTAGC 
CTGGTACACA GCCAGCATGT GTTCCTGGCG CCTCAGCAAG CACTATCGCT GCTCCAGCGG 
GTCCGCAGAG CCAACAGTGG CTTCCTGGAG GAGCTCCGAA AGGGCAACCT AGAGCGTGAG 
TGCGTGGAAG AGCAGTGCAG CTATGAGGAG GCCTTTGAGG CCCTGGAGTC TCCCCAAGAC 
ACAGACGTGT TCTGGGCCAA GTACACAGTG TGTGATTCAG TGAGGAAACC TCGAGAGACT 
TTCATGGACT GTCTGGAAGG TCGCTGTGCT ATGGATCTGG GTGTGAACTA CCTTGGGACT 
GTGAATGTCA CCCATACCGG TATCCAGTGC CAGCTGTGGC GGAGCCGCTA CCCCCACAAG 
CCTGAAATCA ACTCCACCAC CCATCCTGGG GCAGACCTGA AGGAGAACTT CTGCCGCAAT 
CCAGACAGCA GTACCACGGG ACCCTGGTGC TACACCACAG ATCCTACTGT GCGCAGAGAG 
GAATGCAGTG TCCCTGTCTG TGGCCAGGAG GGCCGTACCA CTGTGGTGAT GACTCCTCGC 
TCTGGAGGTT CCAAGGACAA TCTGTCACCT CCACTGGGAC AGTGCCTCAC TGAGCGTGGC 
CGACTATACC AGGGGAATTT GGCTGTGACA ACACTTGGGT CCCCCTGCCT GCCCTGGAAC 
AGCTTACCAG CCAAGACCCT GAGCAAGTAC CAAGACTTCG ACCCCGAGGT GAAACTCGTG 
GAAAACTTCT GCCGCAACCC AGACTGGGAT GAGGAGGGCG CATGGTGCTA TGTTGCGGGG 
CAGCCTGGCG ACTTTGAATA CTGCAACCTC AACTACTGCG AGGAGGCGGT GGGAGAGGAG 
AACTATGATG TGGACGAGTC CATCGCGGGA CGCACCACCG ATGCGGAGTT CCACACCTTC 
TTCAATGAGA AGACCTTCGG CCTTGGGGAG GCAGACTGTG GCCTGCGGCC TTTGTTCGAG 
AAGAAGTCGT TGAAAGACAC AACCGAAAAG GAGCTTCTTG ACTCTTACAT AGACGGGCGC 
ATCGTGGAGG GCTGGGACGC TGAGAAGGGT ATCGCCCCCT GGCAGGTGAT GCTTTTTCGG 
AAGAGTCCCC AAGAGCTGCT GTGTGGGGCC AGCCTTATCA GTGACCGATG GGTCCTCACT 
GCTGCCCACT GCATTCTGTA CCCACCCTGG GACAAGAACT TCACTGAGAA TGACCTCCTG 
GTGCGCATTG GCAAGCATTC CCGAACCAGA TATGAGCGGA ATGTTGAAAA GATCTCCATG 
CTGGAAAAGA TCTACGTCCA CCCCAGATAT AACTGGCGGG AGAACCTAGA CCGCGATATC 
GCTCTGCTCA AGCTAAAGAA ACCTGTACCC TTCAGTGACT ATATTCACCC CGTGTGTTTG 
CCAGACAAGC AGACAGTAAC CAGCTTGCTC CGGGCTGGTT ATAAAGGGCG GGTGACAGGC 
TGGGGCAACC TTCGGGAGAC ATGGACAACC AACATCAATG AGATACAGCC CAGCGTCCTG 
CAGGTGGTGA ACCTGCCCAT TGTAGAGCGG CCAGTGTGCA AGGCCTCCAC CCGGATTCGA 
ATTACTGACA ACATGTTCTG TGCTGGCTTC AAGGTGAATG ACACCAAGCG AGGAGATGCT 
TGTGAAGGTG ACAGTGGAGG ACCTTTTGTC ATGAAGGCCT CAAGACTATG TTATGGAGAC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

VKOR paralog VKORC1L1 supports vitamin K-dependent protein carboxylation in vivo.
JCI insight3(1)(2018 Jan)
Lacombe J,Rishavy MA,Berkner KL,Ferron M

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F2 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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