Cd5l cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cd5l
Entrez Gene ID	11801
Full Name	CD5 antigen-like
Synonyms	1/6,AAC-11,AI047839,Api6,CT2,Pdp,Sp-alpha,mAIM
General protein information	Preferred Names CD5 antigen-like Names CD5 antigen-like AIM/Spalpha CT-2 Pdp 1/6 apoptosis inhibitor 6 apoptosis inhibitor expressed by macrophages
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 3 Map Location: 3\|3 F1

mRNA and Protein(s)

mRNA	Protein	Name
NM_009690.2	NP_033820.2	CD5 antigen-like precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	CD5L	NP_005885.1
	CD5L	XP_001116945.1
Pan troglodytes (chimpanzee)	CD5L	XP_513905.2
Mus musculus (house mouse)	Cd5l	NP_033820.2
Canis lupus familiaris (dog)	CD5L	XP_005622717.1
Rattus norvegicus (Norway rat)	Cd5l	NP_001020856.1

Gene Ontology
Bibliography

Related articles in PubMed

Apoptosis inhibitor of macrophage ameliorates fungus-induced peritoneal injury model in mice.
Tomita T, Arai S, Kitada K, Mizuno M, Suzuki Y, Sakata F, Nakano D, Hiramoto E, Takei Y, Maruyama S, Nishiyama A, Matsuo S, Miyazaki T, Ito Y
Scientific reports7(1)6450(2017 Jul)

Apoptosis inhibitor of macrophage depletion decreased M1 macrophage accumulation and the incidence of cardiac rupture after myocardial infarction in mice.
Ishikawa S, Noma T, Fu HY, Matsuzaki T, Ishizawa M, Ishikawa K, Murakami K, Nishimoto N, Nishiyama A, Minamino T
PloS one12(11)e0187894(2017)

Impact of feline AIM on the susceptibility of cats to renal disease.
Sugisawa R, Hiramoto E, Matsuoka S, Iwai S, Takai R, Yamazaki T, Mori N, Okada Y, Takeda N, Yamamura KI, Arai T, Arai S, Miyazaki T
Scientific reports635251(2016 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

AIM/CD5L-deficient mice demonstrated a smaller infarct size and less of an inflammatory response via inflammatory pathways after myocardial infarction; these data provide the first evidence that AIM/CD5L plays an important role in the inflammatory responses after myocardial injury
Title: Deletion of Apoptosis Inhibitor of Macrophage (AIM)/CD5L Attenuates the Inflammatory Response and Infarct Size in Acute Myocardial Infarction.

AIM enhances intratubular debris clearance and ameliorates acute kidney injury via interaction with KIM-1.
Title: Apoptosis inhibitor of macrophage protein enhances intraluminal debris clearance and ameliorates acute kidney injury in mice.

CD5L as a critical regulator that distinguishes Th17 functional states and identified T cell lipid metabolism as an integral component of the pathways regulating Th17 cell pathogenicity.
Title: CD5L/AIM Regulates Lipid Biosynthesis and Restrains Th17 Cell Pathogenicity.

plays a general homeostatic role by supporting innate immunity during pathogen aggression
Title: The macrophage soluble receptor AIM/Api6/CD5L displays a broad pathogen recognition spectrum and is involved in early response to microbial aggression.

the assembled p40-CD5L heterodimer does not recapitulate the biological activity of IL-12.
Title: Free IL-12p40 monomer is a polyfunctional adaptor for generating novel IL-12-like heterodimers extracellularly.

The following Cd5l gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cd5l cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu04668	NM_009690.2 Latest version!	Mus musculus CD5 antigen-like (Cd5l), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cd5l ( NM_009690.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_033820.2 Mus musculus CD5 antigen-like (Cd5l), mRNA.

Price & Availability↑

CloneID	OMu04668
Clone ID Related Accession (Same CDS sequence)	NM_009690.2
Accession Version	NM_009690.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1059bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Mus musculus(house mouse)
Product	CD5 antigen-like precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK159181.1 and BY582711.1. On Nov 16, 2007 this sequence version replaced NM_009690.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK159181.1, AK159823.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849381 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTCCAT TGTTCAACTT GATGCTGGCC ATCTTGAGCA TTTTTGTTGG ATCGTGTTTT 
TCAGAGTCTC CAACCAAAGT GCAGCTAGTG GGAGGTGCCC ACCGCTGTGA AGGGCGAGTG 
GAGGTGGAAC ACAATGGCCA GTGGGGGACT GTGTGTGATG ATGGCTGGGA CCGGCGTGAT 
GTGGCTGTGG TGTGCCGAGA GCTCAATTGT GGAGCAGTCA TCCAAACCCC GCGTGGCGCA 
TCATATCAGC CACCAGCATC AGAGCAAAGA GTTCTTATTC AAGGGGTTGA CTGCAACGGA 
ACGGAAGACA CGTTGGCTCA ATGTGAGCTA AATTACGATG TTTTTGACTG CTCACATGAA 
GAAGATGCTG GGGCACAGTG TGAGAACCCA GACAGTGACC TCCTCTTCAT TCCAGAGGAT 
GTGCGTCTAG TAGATGGCCC GGGGCACTGC CAGGGTCGAG TGGAGGTGCT CCACCAGTCC 
CAGTGGAGCA CTGTGTGTAA AGCAGGCTGG AACTTACAGG TCTCAAAGGT GGTGTGCAGG 
CAGCTCGGGT GTGGGCGGGC ATTACTGACC TACGGAAGCT GCAACAAGAA TACTCAGGGC 
AAAGGACCCA TCTGGATGGG CAAGATGTCG TGTTCTGGAC AAGAAGCAAA CCTTCGGTCT 
TGCCTTTTGA GTCGTTTGGA GAACAACTGT ACCCATGGCG AGGACACATG GATGGAATGT 
GAAGATCCTT TTGAGCTGAA GCTGGTGGGA GGAGACACCC CCTGCTCTGG GAGGTTGGAG 
GTGCTACACA AGGGTTCCTG GGGCTCTGTC TGTGATGACA ACTGGGGAGA AAAGGAGGAC 
CAAGTGGTCT GCAAGCAACT GGGTTGTGGG AAGTCCCTCC ATCCATCCCC CAAAACCCGG 
AAAATCTATG GGCCTGGGGC AGGCCGCATC TGGCTGGATG ACGTCAACTG CTCAGGGAAG 
GAACAGTCTC TGGAGTTCTG CCGGCACAGG TTGTGGGGGT ACCACGACTG TACCCACAAG 
GAAGATGTGG AGGTGATCTG CACAGACTTT GATGTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_033820.2
CDS	122..1180
Translation	MAPLFNLMLAILSIFVGSCFSESPTKVQLVGGAHRCEGRVEVEHNGQWGTVCDDGWDRRDVAVVCRELNCGAVIQTPRGASYQPPASEQRVLIQGVDCNGTEDTLAQCELNYDVFDCSHEEDAGAQCENPDSDLLFIPEDVRLVDGPGHCQGRVEVLHQSQWSTVCKAGWNLQVSKVVCRQLGCGRALLTYGSCNKNTQGKGPIWMGKMSCSGQEANLRSCLLSRLENNCTHGEDTWMECEDPFELKLVGGDTPCSGRLEVLHKGSWGSVCDDNWGEKEDQVVCKQLGCGKSLHPSPKTRKIYGPGAGRIWLDDVNCSGKEQSLEFCRHRLWGYHDCTHKEDVEVICTDFDV

Target ORF information:

RefSeq Version	NM_009690.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus CD5 antigen-like (Cd5l), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_009690.2

ORF Insert Sequence:

ATGGCTCCAT TGTTCAACTT GATGCTGGCC ATCTTGAGCA TTTTTGTTGG ATCGTGTTTT 
TCAGAGTCTC CAACCAAAGT GCAGCTAGTG GGAGGTGCCC ACCGCTGTGA AGGGCGAGTG 
GAGGTGGAAC ACAATGGCCA GTGGGGGACT GTGTGTGATG ATGGCTGGGA CCGGCGTGAT 
GTGGCTGTGG TGTGCCGAGA GCTCAATTGT GGAGCAGTCA TCCAAACCCC GCGTGGCGCA 
TCATATCAGC CACCAGCATC AGAGCAAAGA GTTCTTATTC AAGGGGTTGA CTGCAACGGA 
ACGGAAGACA CGTTGGCTCA ATGTGAGCTA AATTACGATG TTTTTGACTG CTCACATGAA 
GAAGATGCTG GGGCACAGTG TGAGAACCCA GACAGTGACC TCCTCTTCAT TCCAGAGGAT 
GTGCGTCTAG TAGATGGCCC GGGGCACTGC CAGGGTCGAG TGGAGGTGCT CCACCAGTCC 
CAGTGGAGCA CTGTGTGTAA AGCAGGCTGG AACTTACAGG TCTCAAAGGT GGTGTGCAGG 
CAGCTCGGGT GTGGGCGGGC ATTACTGACC TACGGAAGCT GCAACAAGAA TACTCAGGGC 
AAAGGACCCA TCTGGATGGG CAAGATGTCG TGTTCTGGAC AAGAAGCAAA CCTTCGGTCT 
TGCCTTTTGA GTCGTTTGGA GAACAACTGT ACCCATGGCG AGGACACATG GATGGAATGT 
GAAGATCCTT TTGAGCTGAA GCTGGTGGGA GGAGACACCC CCTGCTCTGG GAGGTTGGAG 
GTGCTACACA AGGGTTCCTG GGGCTCTGTC TGTGATGACA ACTGGGGAGA AAAGGAGGAC 
CAAGTGGTCT GCAAGCAACT GGGTTGTGGG AAGTCCCTCC ATCCATCCCC CAAAACCCGG 
AAAATCTATG GGCCTGGGGC AGGCCGCATC TGGCTGGATG ACGTCAACTG CTCAGGGAAG 
GAACAGTCTC TGGAGTTCTG CCGGCACAGG TTGTGGGGGT ACCACGACTG TACCCACAAG 
GAAGATGTGG AGGTGATCTG CACAGACTTT GATGTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Apoptosis inhibitor of macrophage ameliorates fungus-induced peritoneal injury model in mice.
Scientific reports7(1)6450(2017 Jul)
Tomita T,Arai S,Kitada K,Mizuno M,Suzuki Y,Sakata F,Nakano D,Hiramoto E,Takei Y,Maruyama S,Nishiyama A,Matsuo S,Miyazaki T,Ito Y

Apoptosis inhibitor of macrophage depletion decreased M1 macrophage accumulation and the incidence of cardiac rupture after myocardial infarction in mice.
PloS one12(11)e0187894(2017)
Ishikawa S,Noma T,Fu HY,Matsuzaki T,Ishizawa M,Ishikawa K,Murakami K,Nishimoto N,Nishiyama A,Minamino T

Impact of feline AIM on the susceptibility of cats to renal disease.
Scientific reports635251(2016 Oct)
Sugisawa R,Hiramoto E,Matsuoka S,Iwai S,Takai R,Yamazaki T,Mori N,Okada Y,Takeda N,Yamamura KI,Arai T,Arai S,Miyazaki T

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Cd5l cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

見積依頼

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オンラインフォーム

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