Akp3 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Akp3
Entrez Gene ID	11648
Full Name	alkaline phosphatase 3, intestine, not Mn requiring
Synonyms	Akp-3,IAP,dIAP
General protein information	Preferred Names alkaline phosphatase 3, intestine, not Mn requiring Names intestinal-type alkaline phosphatase intestinal alkaline phosphatase
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 1 Map Location: 1 C5\|1 44.06 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_007432.3	NP_031458.2	intestinal-type alkaline phosphatase precursor
NM_007432.2	NP_031458.2	intestinal-type alkaline phosphatase precursor

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	ALPP	XP_534605.5
Bos taurus (cattle)	LOC528262	XP_002685648.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP011302	XP_309345.4
Homo sapiens (human)	ALPI	NP_001622.2
Pan troglodytes (chimpanzee)	ALPI	XP_003309566.1
Mus musculus (house mouse)	Akp3	NP_031458.2
Rattus norvegicus (Norway rat)	Akp3	NP_073171.1
Bos taurus (cattle)	LOC100125266	NP_001096792.1
Gallus gallus (chicken)	ALPP	XP_003641809.1
Danio rerio (zebrafish)	alpi.2	NP_001020359.1
Drosophila melanogaster (fruit fly)	CG5150	NP_647977.1
Drosophila melanogaster (fruit fly)	CG10827	NP_650931.1
Bos taurus (cattle)	ALPI	XP_005203102.1
Bos taurus (cattle)	LOC516378	XP_002685647.1
Xenopus tropicalis (tropical clawed frog)	alpi.1	XP_002937387.2

Gene Ontology
Bibliography

Related articles in PubMed

Intestinal NCoR1, a regulator of epithelial cell maturation, controls neonatal hyperbilirubinemia.
Chen S, Lu W, Yueh MF, Rettenmeier E, Liu M, Auwerx J, Yu RT, Evans RM, Wang K, Karin M, Tukey RH
Proceedings of the National Academy of Sciences of the United States of America114(8)E1432-E1440(2017 02)

Intestinal alkaline phosphatase deficiency leads to lipopolysaccharide desensitization and faster weight gain.
Yang Y, Mill?n JL, Mecsas J, Guillemin K
Infection and immunity83(1)247-58(2015 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Authors found that Akp3(-/-) mice acquired lipopolysaccharide tolerance during postweaning development, suggesting that Akp3 plays an important role in immune education.
Title: Intestinal alkaline phosphatase deficiency leads to lipopolysaccharide desensitization and faster weight gain.

Intestinal alkaline phosphatase prevents metabolic syndrome in mice.
Title: Intestinal alkaline phosphatase prevents metabolic syndrome in mice.

These data suggest that IAP is a local immunomodulating factor, perhaps regulating LPS-toll-like receptor 4 (TLR4) interaction between commensal microflora and intestinal epithelium.
Title: A role for intestinal alkaline phosphatase in the maintenance of local gut immunity.

Intestinal alkaline phosphatase activity may have a role in mediating the accelerated fatty acid intake observed in Akp3 knockout mice fed a high-fat diet.
Title: A novel phosphatase upregulated in Akp3 knockout mice.

forced high-fat chow induced an 18% greater body weight gain, hepatic steatosis, and visceral fat accumulation in female Akp3(-/-) mice but not in female wild-type controls. there is 2X increase of lipid absorption in Akp3(-/-) male mice.
Title: Disruption of the murine intestinal alkaline phosphatase gene Akp3 impairs lipid transcytosis and induces visceral fat accumulation and hepatic steatosis.

The following Akp3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Akp3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu15071	NM_007432.3 Latest version!	Mus musculus alkaline phosphatase 3, intestine, not Mn requiring (Akp3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	10-12	$328.30 $469.00
View Old Accession Versions >>
OMu15071	NM_007432.2	Mus musculus alkaline phosphatase 3, intestine, not Mn requiring (Akp3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	10-12	$328.30 $469.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Akp3 ( NM_007432.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_031458.2 Mus musculus alkaline phosphatase 3, intestine, not Mn requiring (Akp3), mRNA.

Price & Availability↑

CloneID	OMu15071
Clone ID Related Accession (Same CDS sequence)	NM_007432.3 , NM_007432.2
Accession Version	NM_007432.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1680bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-04
Organism	Mus musculus(house mouse)
Product	intestinal-type alkaline phosphatase precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC102611.10. On Jun 17, 2019 this sequence version replaced NM_007432.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC115745.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849377, SAMN00849378 [ECO:0000348] ##Evidence-Data-END##

ATGCAGGGCA CCTGGGTGCT GCTGCTGCTG GGCCTCAGGC TACAGCTGTC CCTTAGTGTC 
ATTCCAGTGG AGGAGGAGAA CCCGGCCTTC TGGAACAAGA AGGCAGCCGA GGCCCTGGAT 
GCTGCCAAGA AGCTGCAGCC CATTCAGACA TCAGCTAAGA ACCTCATCAT CTTCCTGGGT 
GACGGGATGG GGGTACCAAC AGTGACAGCC ACCAGGATCC TAAAGGGACA GTTGGAAGGT 
CATCTAGGAC CTGAGACACC CCTAGCCATG GACCGCTTCC CATATATGGC TCTGTCCAAG 
ACATACAGTG TGGACAGACA GGTTCCAGAC AGTGCAAGCA CGGCCACCGC CTACCTGTGT 
GGGGTCAAGA CCAACTACAA GACCATCGGC GTGAGCGCAG CCGCGAGATT CGACCAGTGC 
AACACCACAT TTGGCAATGA GGTCTTCTCA GTGATGTACC GTGCCAAGAA AGCAGGAAAA 
TCCGTAGGTG TGGTGACCAC CACCAGAGTG CAGCACGCCT CTCCCTCGGG CACATATGTT 
CACACAGTGA ACCGCAATTG GTATGGGGAT GCTGACATGC CTGCCTCTGC GCTGCGGGAA 
GGTTGCAAGG ACATTGCTAC ACAACTCATC TCCAACATGG ACATTAATGT GATCCTTGGT 
GGGGGCCGAA AATACATGTT TCCTGCTGGA ACCCCAGACC CCGAGTATCC AAATGATGCT 
AATGAGACTG GAACCAGATT GGATGGCAGG AATCTGGTGC AGGAATGGCT GTCAAAGCAC 
CAGGGATCCC AGTATGTTTG GAATCGTGAA CAACTCATTC AGAAGGCCCA GGATCCGTCA 
GTGACATACC TCATGGGCCT CTTTGAGCCT GTAGACACAA AATTTGATAT TCAACGAGAT 
CCCCTGATGG ACCCATCTCT GAAGGATATG ACAGAGGCGG CCGTGAAAGT GCTAAGCAGG 
AACCCCAAAG GCTTTTATCT CTTTGTGGAG GGGGGCCGAA TCGACCGTGG TCACCATCTG 
GGCACAGCTT ATCTGGCGCT GACTGAGGCT GTGATGTTCG ACTTAGCCAT CGAGAGGGCC 
AGCCAGCTCA CTAGTGAACG CGACACTCTG ACCATAGTCA CTGCTGACCA CTCCCATGTC 
TTCTCCTTTG GTGGCTACAC ACTTCGAGGG ACCTCCATCT TCGGGCTGGC TCCCCTCAAT 
GCTCTGGACG GCAAGCCCTA CACCTCCATC CTGTATGGCA ACGGCCCAGG CTATGTCGGT 
ACAGGGGAAA GACCCAACGT CACCGCCGCT GAAAGCAGTG GCTCATCGTA CCGGCAGCAG 
GCTGCTGTGC CGGTGAAGTC GGAGACCCAC GGCGGGGAGG ACGTGGCGAT ATTCGCGCGT 
GGCCCGCAGG CGCACTTGCT GCACGGGGTG CAGGAGCAGA ACTACATCGC GCACGTCATG 
GCCTTCGCAG GCTGCCTGGA GCCCTACACC GACTGCGGCT TGGCACCCCC TGCAGATGAA 
AGCCAGACCA CCACGACAAC CCGCCAGACC ACCATCACCA CCACCACCAC CACCACCACC 
ACCACAACCA CCCCGGTCCA TAACAGCGCC AGAAGCCTGG GCCCAGCCAC CGCCCCGCTG 
GCTCTGGCGC TGCTGGCCGG AATGCTGATG CTACTACTAG GGGCTCCTGC GGAGTCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_031458.2
CDS	55..1734
Translation	MQGTWVLLLLGLRLQLSLSVIPVEEENPAFWNKKAAEALDAAKKLQPIQTSAKNLIIFLGDGMGVPTVTATRILKGQLEGHLGPETPLAMDRFPYMALSKTYSVDRQVPDSASTATAYLCGVKTNYKTIGVSAAARFDQCNTTFGNEVFSVMYRAKKAGKSVGVVTTTRVQHASPSGTYVHTVNRNWYGDADMPASALREGCKDIATQLISNMDINVILGGGRKYMFPAGTPDPEYPNDANETGTRLDGRNLVQEWLSKHQGSQYVWNREQLIQKAQDPSVTYLMGLFEPVDTKFDIQRDPLMDPSLKDMTEAAVKVLSRNPKGFYLFVEGGRIDRGHHLGTAYLALTEAVMFDLAIERASQLTSERDTLTIVTADHSHVFSFGGYTLRGTSIFGLAPLNALDGKPYTSILYGNGPGYVGTGERPNVTAAESSGSSYRQQAAVPVKSETHGGEDVAIFARGPQAHLLHGVQEQNYIAHVMAFAGCLEPYTDCGLAPPADESQTTTTTRQTTITTTTTTTTTTTTPVHNSARSLGPATAPLALALLAGMLMLLLGAPAES

Target ORF information:

RefSeq Version	NM_007432.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus alkaline phosphatase 3, intestine, not Mn requiring (Akp3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007432.3

ORF Insert Sequence:

ATGCAGGGCA CCTGGGTGCT GCTGCTGCTG GGCCTCAGGC TACAGCTGTC CCTTAGTGTC 
ATTCCAGTGG AGGAGGAGAA CCCGGCCTTC TGGAACAAGA AGGCAGCCGA GGCCCTGGAT 
GCTGCCAAGA AGCTGCAGCC CATTCAGACA TCAGCTAAGA ACCTCATCAT CTTCCTGGGT 
GACGGGATGG GGGTACCAAC AGTGACAGCC ACCAGGATCC TAAAGGGACA GTTGGAAGGT 
CATCTAGGAC CTGAGACACC CCTAGCCATG GACCGCTTCC CATATATGGC TCTGTCCAAG 
ACATACAGTG TGGACAGACA GGTTCCAGAC AGTGCAAGCA CGGCCACCGC CTACCTGTGT 
GGGGTCAAGA CCAACTACAA GACCATCGGC GTGAGCGCAG CCGCGAGATT CGACCAGTGC 
AACACCACAT TTGGCAATGA GGTCTTCTCA GTGATGTACC GTGCCAAGAA AGCAGGAAAA 
TCCGTAGGTG TGGTGACCAC CACCAGAGTG CAGCACGCCT CTCCCTCGGG CACATATGTT 
CACACAGTGA ACCGCAATTG GTATGGGGAT GCTGACATGC CTGCCTCTGC GCTGCGGGAA 
GGTTGCAAGG ACATTGCTAC ACAACTCATC TCCAACATGG ACATTAATGT GATCCTTGGT 
GGGGGCCGAA AATACATGTT TCCTGCTGGA ACCCCAGACC CCGAGTATCC AAATGATGCT 
AATGAGACTG GAACCAGATT GGATGGCAGG AATCTGGTGC AGGAATGGCT GTCAAAGCAC 
CAGGGATCCC AGTATGTTTG GAATCGTGAA CAACTCATTC AGAAGGCCCA GGATCCGTCA 
GTGACATACC TCATGGGCCT CTTTGAGCCT GTAGACACAA AATTTGATAT TCAACGAGAT 
CCCCTGATGG ACCCATCTCT GAAGGATATG ACAGAGGCGG CCGTGAAAGT GCTAAGCAGG 
AACCCCAAAG GCTTTTATCT CTTTGTGGAG GGGGGCCGAA TCGACCGTGG TCACCATCTG 
GGCACAGCTT ATCTGGCGCT GACTGAGGCT GTGATGTTCG ACTTAGCCAT CGAGAGGGCC 
AGCCAGCTCA CTAGTGAACG CGACACTCTG ACCATAGTCA CTGCTGACCA CTCCCATGTC 
TTCTCCTTTG GTGGCTACAC ACTTCGAGGG ACCTCCATCT TCGGGCTGGC TCCCCTCAAT 
GCTCTGGACG GCAAGCCCTA CACCTCCATC CTGTATGGCA ACGGCCCAGG CTATGTCGGT 
ACAGGGGAAA GACCCAACGT CACCGCCGCT GAAAGCAGTG GCTCATCGTA CCGGCAGCAG 
GCTGCTGTGC CGGTGAAGTC GGAGACCCAC GGCGGGGAGG ACGTGGCGAT ATTCGCGCGT 
GGCCCGCAGG CGCACTTGCT GCACGGGGTG CAGGAGCAGA ACTACATCGC GCACGTCATG 
GCCTTCGCAG GCTGCCTGGA GCCCTACACC GACTGCGGCT TGGCACCCCC TGCAGATGAA 
AGCCAGACCA CCACGACAAC CCGCCAGACC ACCATCACCA CCACCACCAC CACCACCACC 
ACCACAACCA CCCCGGTCCA TAACAGCGCC AGAAGCCTGG GCCCAGCCAC CGCCCCGCTG 
GCTCTGGCGC TGCTGGCCGG AATGCTGATG CTACTACTAG GGGCTCCTGC GGAGTCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Akp3 ( NM_007432.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_031458.2 Mus musculus alkaline phosphatase 3, intestine, not Mn requiring (Akp3), mRNA.

Price & Availability↑

CloneID	OMu15071
Clone ID Related Accession (Same CDS sequence)	NM_007432.3 , NM_007432.2
Accession Version	NM_007432.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1680bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-16
Organism	Mus musculus(house mouse)
Product	intestinal-type alkaline phosphatase precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC102611.10 and BC115745.1. On Jul 14, 2006 this sequence version replaced NM_007432.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC115745.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849377, SAMN00849378 [ECO:0000348] ##Evidence-Data-END##

ATGCAGGGCA CCTGGGTGCT GCTGCTGCTG GGCCTCAGGC TACAGCTGTC CCTTAGTGTC 
ATTCCAGTGG AGGAGGAGAA CCCGGCCTTC TGGAACAAGA AGGCAGCCGA GGCCCTGGAT 
GCTGCCAAGA AGCTGCAGCC CATTCAGACA TCAGCTAAGA ACCTCATCAT CTTCCTGGGT 
GACGGGATGG GGGTACCAAC AGTGACAGCC ACCAGGATCC TAAAGGGACA GTTGGAAGGT 
CATCTAGGAC CTGAGACACC CCTAGCCATG GACCGCTTCC CATATATGGC TCTGTCCAAG 
ACATACAGTG TGGACAGACA GGTTCCAGAC AGTGCAAGCA CGGCCACCGC CTACCTGTGT 
GGGGTCAAGA CCAACTACAA GACCATCGGC GTGAGCGCAG CCGCGAGATT CGACCAGTGC 
AACACCACAT TTGGCAATGA GGTCTTCTCA GTGATGTACC GTGCCAAGAA AGCAGGAAAA 
TCCGTAGGTG TGGTGACCAC CACCAGAGTG CAGCACGCCT CTCCCTCGGG CACATATGTT 
CACACAGTGA ACCGCAATTG GTATGGGGAT GCTGACATGC CTGCCTCTGC GCTGCGGGAA 
GGTTGCAAGG ACATTGCTAC ACAACTCATC TCCAACATGG ACATTAATGT GATCCTTGGT 
GGGGGCCGAA AATACATGTT TCCTGCTGGA ACCCCAGACC CCGAGTATCC AAATGATGCT 
AATGAGACTG GAACCAGATT GGATGGCAGG AATCTGGTGC AGGAATGGCT GTCAAAGCAC 
CAGGGATCCC AGTATGTTTG GAATCGTGAA CAACTCATTC AGAAGGCCCA GGATCCGTCA 
GTGACATACC TCATGGGCCT CTTTGAGCCT GTAGACACAA AATTTGATAT TCAACGAGAT 
CCCCTGATGG ACCCATCTCT GAAGGATATG ACAGAGGCGG CCGTGAAAGT GCTAAGCAGG 
AACCCCAAAG GCTTTTATCT CTTTGTGGAG GGGGGCCGAA TCGACCGTGG TCACCATCTG 
GGCACAGCTT ATCTGGCGCT GACTGAGGCT GTGATGTTCG ACTTAGCCAT CGAGAGGGCC 
AGCCAGCTCA CTAGTGAACG CGACACTCTG ACCATAGTCA CTGCTGACCA CTCCCATGTC 
TTCTCCTTTG GTGGCTACAC ACTTCGAGGG ACCTCCATCT TCGGGCTGGC TCCCCTCAAT 
GCTCTGGACG GCAAGCCCTA CACCTCCATC CTGTATGGCA ACGGCCCAGG CTATGTCGGT 
ACAGGGGAAA GACCCAACGT CACCGCCGCT GAAAGCAGTG GCTCATCGTA CCGGCAGCAG 
GCTGCTGTGC CGGTGAAGTC GGAGACCCAC GGCGGGGAGG ACGTGGCGAT ATTCGCGCGT 
GGCCCGCAGG CGCACTTGCT GCACGGGGTG CAGGAGCAGA ACTACATCGC GCACGTCATG 
GCCTTCGCAG GCTGCCTGGA GCCCTACACC GACTGCGGCT TGGCACCCCC TGCAGATGAA 
AGCCAGACCA CCACGACAAC CCGCCAGACC ACCATCACCA CCACCACCAC CACCACCACC 
ACCACAACCA CCCCGGTCCA TAACAGCGCC AGAAGCCTGG GCCCAGCCAC CGCCCCGCTG 
GCTCTGGCGC TGCTGGCCGG AATGCTGATG CTACTACTAG GGGCTCCTGC GGAGTCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_031458.2
CDS	1..1680
Translation	MQGTWVLLLLGLRLQLSLSVIPVEEENPAFWNKKAAEALDAAKKLQPIQTSAKNLIIFLGDGMGVPTVTATRILKGQLEGHLGPETPLAMDRFPYMALSKTYSVDRQVPDSASTATAYLCGVKTNYKTIGVSAAARFDQCNTTFGNEVFSVMYRAKKAGKSVGVVTTTRVQHASPSGTYVHTVNRNWYGDADMPASALREGCKDIATQLISNMDINVILGGGRKYMFPAGTPDPEYPNDANETGTRLDGRNLVQEWLSKHQGSQYVWNREQLIQKAQDPSVTYLMGLFEPVDTKFDIQRDPLMDPSLKDMTEAAVKVLSRNPKGFYLFVEGGRIDRGHHLGTAYLALTEAVMFDLAIERASQLTSERDTLTIVTADHSHVFSFGGYTLRGTSIFGLAPLNALDGKPYTSILYGNGPGYVGTGERPNVTAAESSGSSYRQQAAVPVKSETHGGEDVAIFARGPQAHLLHGVQEQNYIAHVMAFAGCLEPYTDCGLAPPADESQTTTTTRQTTITTTTTTTTTTTTPVHNSARSLGPATAPLALALLAGMLMLLLGAPAES

Target ORF information:

RefSeq Version	NM_007432.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus alkaline phosphatase 3, intestine, not Mn requiring (Akp3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007432.2

ORF Insert Sequence:

ATGCAGGGCA CCTGGGTGCT GCTGCTGCTG GGCCTCAGGC TACAGCTGTC CCTTAGTGTC 
ATTCCAGTGG AGGAGGAGAA CCCGGCCTTC TGGAACAAGA AGGCAGCCGA GGCCCTGGAT 
GCTGCCAAGA AGCTGCAGCC CATTCAGACA TCAGCTAAGA ACCTCATCAT CTTCCTGGGT 
GACGGGATGG GGGTACCAAC AGTGACAGCC ACCAGGATCC TAAAGGGACA GTTGGAAGGT 
CATCTAGGAC CTGAGACACC CCTAGCCATG GACCGCTTCC CATATATGGC TCTGTCCAAG 
ACATACAGTG TGGACAGACA GGTTCCAGAC AGTGCAAGCA CGGCCACCGC CTACCTGTGT 
GGGGTCAAGA CCAACTACAA GACCATCGGC GTGAGCGCAG CCGCGAGATT CGACCAGTGC 
AACACCACAT TTGGCAATGA GGTCTTCTCA GTGATGTACC GTGCCAAGAA AGCAGGAAAA 
TCCGTAGGTG TGGTGACCAC CACCAGAGTG CAGCACGCCT CTCCCTCGGG CACATATGTT 
CACACAGTGA ACCGCAATTG GTATGGGGAT GCTGACATGC CTGCCTCTGC GCTGCGGGAA 
GGTTGCAAGG ACATTGCTAC ACAACTCATC TCCAACATGG ACATTAATGT GATCCTTGGT 
GGGGGCCGAA AATACATGTT TCCTGCTGGA ACCCCAGACC CCGAGTATCC AAATGATGCT 
AATGAGACTG GAACCAGATT GGATGGCAGG AATCTGGTGC AGGAATGGCT GTCAAAGCAC 
CAGGGATCCC AGTATGTTTG GAATCGTGAA CAACTCATTC AGAAGGCCCA GGATCCGTCA 
GTGACATACC TCATGGGCCT CTTTGAGCCT GTAGACACAA AATTTGATAT TCAACGAGAT 
CCCCTGATGG ACCCATCTCT GAAGGATATG ACAGAGGCGG CCGTGAAAGT GCTAAGCAGG 
AACCCCAAAG GCTTTTATCT CTTTGTGGAG GGGGGCCGAA TCGACCGTGG TCACCATCTG 
GGCACAGCTT ATCTGGCGCT GACTGAGGCT GTGATGTTCG ACTTAGCCAT CGAGAGGGCC 
AGCCAGCTCA CTAGTGAACG CGACACTCTG ACCATAGTCA CTGCTGACCA CTCCCATGTC 
TTCTCCTTTG GTGGCTACAC ACTTCGAGGG ACCTCCATCT TCGGGCTGGC TCCCCTCAAT 
GCTCTGGACG GCAAGCCCTA CACCTCCATC CTGTATGGCA ACGGCCCAGG CTATGTCGGT 
ACAGGGGAAA GACCCAACGT CACCGCCGCT GAAAGCAGTG GCTCATCGTA CCGGCAGCAG 
GCTGCTGTGC CGGTGAAGTC GGAGACCCAC GGCGGGGAGG ACGTGGCGAT ATTCGCGCGT 
GGCCCGCAGG CGCACTTGCT GCACGGGGTG CAGGAGCAGA ACTACATCGC GCACGTCATG 
GCCTTCGCAG GCTGCCTGGA GCCCTACACC GACTGCGGCT TGGCACCCCC TGCAGATGAA 
AGCCAGACCA CCACGACAAC CCGCCAGACC ACCATCACCA CCACCACCAC CACCACCACC 
ACCACAACCA CCCCGGTCCA TAACAGCGCC AGAAGCCTGG GCCCAGCCAC CGCCCCGCTG 
GCTCTGGCGC TGCTGGCCGG AATGCTGATG CTACTACTAG GGGCTCCTGC GGAGTCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Intestinal NCoR1, a regulator of epithelial cell maturation, controls neonatal hyperbilirubinemia.
Proceedings of the National Academy of Sciences of the United States of America114(8)E1432-E1440(2017 02)
Chen S,Lu W,Yueh MF,Rettenmeier E,Liu M,Auwerx J,Yu RT,Evans RM,Wang K,Karin M,Tukey RH

Intestinal alkaline phosphatase deficiency leads to lipopolysaccharide desensitization and faster weight gain.
Infection and immunity83(1)247-58(2015 Jan)
Yang Y,Mill?n JL,Mecsas J,Guillemin K