Gene Symbol | ALPI |
Entrez Gene ID | 280993 |
Full Name | alkaline phosphatase, intestinal |
Synonyms | IAP |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
Genome |
ORF » Species Summary » Bos taurus » ALPI cDNA ORF clone
Gene Symbol | ALPI |
Entrez Gene ID | 280993 |
Full Name | alkaline phosphatase, intestinal |
Synonyms | IAP |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_173987.2 | NP_776412.2 | intestinal-type alkaline phosphatase precursor |
Canis lupus familiaris (dog) | ALPP | XP_534605.5 |
Bos taurus (cattle) | LOC528262 | XP_002685648.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP011302 | XP_309345.4 |
Homo sapiens (human) | ALPI | NP_001622.2 |
Pan troglodytes (chimpanzee) | ALPI | XP_003309566.1 |
Mus musculus (house mouse) | Akp3 | NP_031458.2 |
Rattus norvegicus (Norway rat) | Akp3 | NP_073171.1 |
Bos taurus (cattle) | LOC100125266 | NP_001096792.1 |
Gallus gallus (chicken) | ALPP | XP_003641809.1 |
Danio rerio (zebrafish) | alpi.2 | NP_001020359.1 |
Drosophila melanogaster (fruit fly) | CG5150 | NP_647977.1 |
Drosophila melanogaster (fruit fly) | CG10827 | NP_650931.1 |
Bos taurus (cattle) | ALPI | XP_005203102.1 |
Bos taurus (cattle) | LOC516378 | XP_002685647.1 |
Xenopus tropicalis (tropical clawed frog) | alpi.1 | XP_002937387.2 |
Prophylactic treatment with alkaline phosphatase in cardiac surgery induces endogenous alkaline phosphatase release.
Kats S, Brands R, Hamad MA, Seinen W, Scharnhorst V, Wulkan RW, Sch?nberger JP, Oeveren Wv
The International journal of artificial organs35(2)144-51(2012 Feb)
Identification of specific targets for the gut mucosal defense factor intestinal alkaline phosphatase.
Chen KT, Malo MS, Moss AK, Zeller S, Johnson P, Ebrahimi F, Mostafa G, Alam SN, Ramasamy S, Warren HS, Hohmann EL, Hodin RA
American journal of physiology. Gastrointestinal and liver physiology299(2)G467-75(2010 Aug)
A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Mar?ais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)
Effect of metal ions on the secondary structure and activity of calf intestine phosphatase.
Chen F, Liu G, Xu Z, Zeng Z
BMB reports41(4)305-9(2008 Apr)
Distinct structure and activity recoveries reveal differences in metal binding between mammalian and Escherichia coli alkaline phosphatases.
Zhang L, Buchet R, Azzar G
The Biochemical journal392(Pt 2)407-15(2005 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Intravenous bolus administration plus 8 hours continuous infusion of alkaline phosphatase in patients undergoing coronary artery bypass grafting with cardiopulmonary bypass results in endogenous alkaline phosphatase release.
Title: Prophylactic treatment with alkaline phosphatase in cardiac surgery induces endogenous alkaline phosphatase release.
Mechanism of IAP action appears to be through dephosphorylation of specific bacterial components, including LPS, CpG DNA, and flagellin, and not on live bacteria. IAP likely targets these bacterially derived molecules as gut mucosal defense factor.
Title: Identification of specific targets for the gut mucosal defense factor intestinal alkaline phosphatase.
Secondary structure of CIP after reaction with Co2+ in different conditions.
Title: Effect of metal ions on the secondary structure and activity of calf intestine phosphatase.
differences in metal binding between bovine and Escherichia coli alkaline phosphatases
Title: Distinct structure and activity recoveries reveal differences in metal binding between mammalian and Escherichia coli alkaline phosphatases.
The following ALPI gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ALPI cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OBa87622 | |
Clone ID Related Accession (Same CDS sequence) | NM_173987.2 | |
Accession Version | NM_173987.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1602bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-28 | |
Organism | Bos taurus(cattle) | |
Product | intestinal-type alkaline phosphatase precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from NKLS02000002.1. On Sep 22, 2015 this sequence version replaced NM_173987.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN03145482 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGCAGGGGG CCTGCGTGCT GCTGCTGCTG GGCCTGCAGC TACAGCTCTC CCTTGGCCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_776412.2 |
CDS | 41..1642 |
Translation |
Target ORF information:
Target ORF information:
|
NM_173987.2 |
1 | ATGCAGGGGG CCTGCGTGCT GCTGCTGCTG GGCCTGCAGC TACAGCTCTC CCTTGGCCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Prophylactic treatment with alkaline phosphatase in cardiac surgery induces endogenous alkaline phosphatase release. |
Identification of specific targets for the gut mucosal defense factor intestinal alkaline phosphatase. |
A whole-genome assembly of the domestic cow, Bos taurus. |
Effect of metal ions on the secondary structure and activity of calf intestine phosphatase. |
Distinct structure and activity recoveries reveal differences in metal binding between mammalian and Escherichia coli alkaline phosphatases. |