Acvr1b cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Acvr1b
Entrez Gene ID	11479
Full Name	activin A receptor, type 1B
Synonyms	6820432J04,ActR-IB,ActRIB,Acvrlk4,Alk4,SKR2
General protein information	Preferred Names activin A receptor, type 1B Names activin receptor type-1B ALK-4 activin receptor type IB activin receptor-like kinase 4 serine/threonine-protein kinase receptor R2
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 15 Map Location: 15 F1\|15 56.48 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_007395.3	NP_031421.1	activin receptor type-1B precursor
NM_007395.4	NP_031421.1	activin receptor type-1B precursor

Pathways from BioSystems

Homologies

	ACVR1B	XP_001091363.1
Gallus gallus (chicken)	ACVR1B	XP_001231301.3
Bos taurus (cattle)	ACVR1B	XP_002687303.1
Mus musculus (house mouse)	Acvr1b	NP_031421.1
Xenopus tropicalis (tropical clawed frog)	acvr1b	NP_001039062.1
Danio rerio (zebrafish)	acvr1b	NP_571065.1
Homo sapiens (human)	ACVR1B	NP_004293.1
Pan troglodytes (chimpanzee)	ACVR1B	XP_001145219.1
Canis lupus familiaris (dog)	ACVR1B	XP_005636858.1
Rattus norvegicus (Norway rat)	Acvr1b	NP_954700.1
Danio rerio (zebrafish)	LOC559222	XP_687633.4

Gene Ontology
Bibliography

Related articles in PubMed

Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System.
Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstr?m E, Pachnis V, Marklund U
Gastroenterology(2017 Oct)

The crucial role of activin A/ALK4 pathway in the pathogenesis of Ang-II-induced atrial fibrosis and vulnerability to atrial fibrillation.
Wang Q, Yu Y, Zhang P, Chen Y, Li C, Chen J, Wang Y, Li Y
Basic research in cardiology112(4)47(2017 Jul)

Haplodeficiency of activin receptor-like kinase 4 alleviates myocardial infarction-induced cardiac fibrosis and preserves cardiac function.
Chen YH, Wang Q, Li CY, Hou JW, Chen XM, Zhou Q, Chen J, Wang YP, Li YG
Journal of molecular and cellular cardiology1051-11(2017 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

ALK4 is an important profibrotic signaling molecule in the post-MI CF. Haplodeficiency of ALK4 significantly improved LV function and survival rate by attenuating CF in vivo, ameliorated
Title: Haplodeficiency of activin receptor-like kinase 4 alleviates myocardial infarction-induced cardiac fibrosis and preserves cardiac function.

Our results demonstrate that ALK4 haploinsufficiency ameliorates cardiac fibrosis and dysfunction in a mouse pressure-overload model associated with inhibition of cardiac fibroblast activation and cardiomyocyte apoptosis through the suppression of Smad2/3 activity.
Title: Partial inhibition of activin receptor-like kinase 4 attenuates pressure overload-induced cardiac fibrosis and improves cardiac function.

Uterine Activin-Like Kinase 4 Regulates Trophoblast Development During Mouse Placentation
Title: Uterine Activin-Like Kinase 4 Regulates Trophoblast Development During Mouse Placentation.

These results indicate that an appropriate level of activin signaling may be required for GSIS in pancreatic beta cells, and that activin signaling involves modulation of KATP channel activity.
Title: Activation of activin type IB receptor signals in pancreatic ? cells leads to defective insulin secretion through the attenuation of ATP-sensitive K+ channel activity.

Signaling through the TGF beta-activin receptors ALK4/5/7 regulates testis formation and male germ cell development.
Title: Signaling through the TGF beta-activin receptors ALK4/5/7 regulates testis formation and male germ cell development.

The following Acvr1b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Acvr1b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu13277	NM_007395.4 Latest version!	Mus musculus activin A receptor, type 1B (Acvr1b), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$300.30 $429.00
View Old Accession Versions >>
OMu13277	NM_007395.3	Mus musculus activin A receptor, type 1B (Acvr1b), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$300.30 $429.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Acvr1b ( NM_007395.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_031421.1 Mus musculus activin A receptor, type 1B (Acvr1b), mRNA.

Price & Availability↑

CloneID	OMu13277
Clone ID Related Accession (Same CDS sequence)	NM_007395.3 , NM_007395.4
Accession Version	NM_007395.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1518bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-11-25
Organism	Mus musculus(house mouse)
Product	activin receptor type-1B precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AK157910.1. On Apr 6, 2007 this sequence version replaced NM_007395.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK157910.1, AK154578.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGGCGGAGT CGGCCGGAGC CTCCTCCTTC TTCCCCCTTG TTGTCCTCCT GCTCGCCGGC 
AGCGGCGGGT CCGGGCCCCG GGGGATCCAG GCTCTGCTGT GTGCGTGCAC CAGCTGCCTA 
CAGACCAACT ACACCTGTGA GACAGATGGG GCTTGCATGG TCTCCATCTT TAACCTGGAT 
GGCGTGGAGC ACCATGTACG TACCTGCATC CCCAAGGTGG AGCTGGTTCC TGCTGGAAAG 
CCCTTCTACT GCCTGAGTTC AGAGGATCTG CGCAACACAC ACTGCTGCTA TATTGACTTC 
TGCAACAAGA TTGACCTCAG GGTCCCCAGC GGACACCTCA AGGAGCCTGC GCACCCCTCC 
ATGTGGGGCC CTGTGGAGCT GGTCGGCATC ATCGCCGGCC CCGTCTTCCT CCTCTTCCTT 
ATCATTATCA TCGTCTTCCT GGTCATCAAC TATCACCAGC GTGTCTACCA TAACCGCCAG 
AGGTTGGACA TGGAGGACCC CTCTTGCGAG ATGTGTCTCT CCAAAGACAA GACGCTCCAG 
GATCTCGTCT ACGACCTCTC CACGTCAGGG TCTGGCTCAG GGTTACCCCT TTTTGTCCAG 
CGCACAGTGG CCCGAACCAT TGTTTTACAA GAGATTATCG GCAAGGGCCG GTTCGGGGAA 
GTATGGCGTG GTCGCTGGAG GGGTGGTGAC GTGGCTGTGA AAATCTTCTC TTCTCGTGAA 
GAACGGTCTT GGTTCCGTGA AGCAGAGATC TACCAGACCG TCATGCTGCG CCATGAAAAC 
ATCCTTGGCT TTATTGCTGC TGACAATAAA GATAATGGCA CCTGGACCCA GCTGTGGCTT 
GTCTCTGACT ATCACGAGCA TGGCTCACTG TTTGATTATC TGAACCGCTA CACAGTGACC 
ATTGAGGGAA TGATTAAGCT AGCCTTGTCT GCAGCCAGTG GTTTGGCACA CCTGCATATG 
GAGATTGTGG GCACTCAAGG GAAGCCGGGA ATTGCTCATC GAGACTTGAA GTCAAAGAAC 
ATCCTGGTGA AAAAAAATGG CATGTGTGCC ATTGCAGACC TGGGCCTGGC TGTCCGTCAT 
GATGCGGTCA CTGACACCAT AGACATTGCT CCAAATCAGA GGGTGGGGAC CAAACGATAC 
ATGGCTCCTG AAGTCCTTGA CGAGACAATC AACATGAAGC ACTTTGACTC CTTCAAATGT 
GCCGACATCT ATGCCCTCGG GCTTGTCTAC TGGGAGATTG CACGAAGATG CAATTCTGGA 
GGAGTCCATG AAGACTATCA ACTGCCGTAT TACGACTTAG TGCCCTCCGA CCCTTCCATT 
GAGGAGATGC GAAAGGTTGT ATGTGACCAG AAGCTACGGC CCAATGTCCC CAACTGGTGG 
CAGAGTTATG AGGCCTTGCG AGTGATGGGA AAGATGATGC GGGAGTGCTG GTACGCCAAT 
GGTGCTGCCC GTCTGACAGC TCTGCGCATC AAGAAGACTC TGTCCCAGCT AAGCGTGCAG 
GAAGATGTGA AGATTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_031421.1
CDS	21..1538
Translation	MAESAGASSFFPLVVLLLAGSGGSGPRGIQALLCACTSCLQTNYTCETDGACMVSIFNLDGVEHHVRTCIPKVELVPAGKPFYCLSSEDLRNTHCCYIDFCNKIDLRVPSGHLKEPAHPSMWGPVELVGIIAGPVFLLFLIIIIVFLVINYHQRVYHNRQRLDMEDPSCEMCLSKDKTLQDLVYDLSTSGSGSGLPLFVQRTVARTIVLQEIIGKGRFGEVWRGRWRGGDVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTIEGMIKLALSAASGLAHLHMEIVGTQGKPGIAHRDLKSKNILVKKNGMCAIADLGLAVRHDAVTDTIDIAPNQRVGTKRYMAPEVLDETINMKHFDSFKCADIYALGLVYWEIARRCNSGGVHEDYQLPYYDLVPSDPSIEEMRKVVCDQKLRPNVPNWWQSYEALRVMGKMMRECWYANGAARLTALRIKKTLSQLSVQEDVKI

Target ORF information:

RefSeq Version	NM_007395.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus activin A receptor, type 1B (Acvr1b), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007395.3

ORF Insert Sequence:

ATGGCGGAGT CGGCCGGAGC CTCCTCCTTC TTCCCCCTTG TTGTCCTCCT GCTCGCCGGC 
AGCGGCGGGT CCGGGCCCCG GGGGATCCAG GCTCTGCTGT GTGCGTGCAC CAGCTGCCTA 
CAGACCAACT ACACCTGTGA GACAGATGGG GCTTGCATGG TCTCCATCTT TAACCTGGAT 
GGCGTGGAGC ACCATGTACG TACCTGCATC CCCAAGGTGG AGCTGGTTCC TGCTGGAAAG 
CCCTTCTACT GCCTGAGTTC AGAGGATCTG CGCAACACAC ACTGCTGCTA TATTGACTTC 
TGCAACAAGA TTGACCTCAG GGTCCCCAGC GGACACCTCA AGGAGCCTGC GCACCCCTCC 
ATGTGGGGCC CTGTGGAGCT GGTCGGCATC ATCGCCGGCC CCGTCTTCCT CCTCTTCCTT 
ATCATTATCA TCGTCTTCCT GGTCATCAAC TATCACCAGC GTGTCTACCA TAACCGCCAG 
AGGTTGGACA TGGAGGACCC CTCTTGCGAG ATGTGTCTCT CCAAAGACAA GACGCTCCAG 
GATCTCGTCT ACGACCTCTC CACGTCAGGG TCTGGCTCAG GGTTACCCCT TTTTGTCCAG 
CGCACAGTGG CCCGAACCAT TGTTTTACAA GAGATTATCG GCAAGGGCCG GTTCGGGGAA 
GTATGGCGTG GTCGCTGGAG GGGTGGTGAC GTGGCTGTGA AAATCTTCTC TTCTCGTGAA 
GAACGGTCTT GGTTCCGTGA AGCAGAGATC TACCAGACCG TCATGCTGCG CCATGAAAAC 
ATCCTTGGCT TTATTGCTGC TGACAATAAA GATAATGGCA CCTGGACCCA GCTGTGGCTT 
GTCTCTGACT ATCACGAGCA TGGCTCACTG TTTGATTATC TGAACCGCTA CACAGTGACC 
ATTGAGGGAA TGATTAAGCT AGCCTTGTCT GCAGCCAGTG GTTTGGCACA CCTGCATATG 
GAGATTGTGG GCACTCAAGG GAAGCCGGGA ATTGCTCATC GAGACTTGAA GTCAAAGAAC 
ATCCTGGTGA AAAAAAATGG CATGTGTGCC ATTGCAGACC TGGGCCTGGC TGTCCGTCAT 
GATGCGGTCA CTGACACCAT AGACATTGCT CCAAATCAGA GGGTGGGGAC CAAACGATAC 
ATGGCTCCTG AAGTCCTTGA CGAGACAATC AACATGAAGC ACTTTGACTC CTTCAAATGT 
GCCGACATCT ATGCCCTCGG GCTTGTCTAC TGGGAGATTG CACGAAGATG CAATTCTGGA 
GGAGTCCATG AAGACTATCA ACTGCCGTAT TACGACTTAG TGCCCTCCGA CCCTTCCATT 
GAGGAGATGC GAAAGGTTGT ATGTGACCAG AAGCTACGGC CCAATGTCCC CAACTGGTGG 
CAGAGTTATG AGGCCTTGCG AGTGATGGGA AAGATGATGC GGGAGTGCTG GTACGCCAAT 
GGTGCTGCCC GTCTGACAGC TCTGCGCATC AAGAAGACTC TGTCCCAGCT AAGCGTGCAG 
GAAGATGTGA AGATTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Acvr1b ( NM_007395.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_031421.1 Mus musculus activin A receptor, type 1B (Acvr1b), mRNA.

Price & Availability↑

CloneID	OMu13277
Clone ID Related Accession (Same CDS sequence)	NM_007395.3 , NM_007395.4
Accession Version	NM_007395.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1518bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-25
Organism	Mus musculus(house mouse)
Product	activin receptor type-1B precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC145775.1, AK157910.1, AK078525.1, AC161812.3 and BC059832.1. On Mar 28, 2018 this sequence version replaced NM_007395.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC145775.1, AK154578.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGAGT CGGCCGGAGC CTCCTCCTTC TTCCCCCTTG TTGTCCTCCT GCTCGCCGGC 
AGCGGCGGGT CCGGGCCCCG GGGGATCCAG GCTCTGCTGT GTGCGTGCAC CAGCTGCCTA 
CAGACCAACT ACACCTGTGA GACAGATGGG GCTTGCATGG TCTCCATCTT TAACCTGGAT 
GGCGTGGAGC ACCATGTACG TACCTGCATC CCCAAGGTGG AGCTGGTTCC TGCTGGAAAG 
CCCTTCTACT GCCTGAGTTC AGAGGATCTG CGCAACACAC ACTGCTGCTA TATTGACTTC 
TGCAACAAGA TTGACCTCAG GGTCCCCAGC GGACACCTCA AGGAGCCTGC GCACCCCTCC 
ATGTGGGGCC CTGTGGAGCT GGTCGGCATC ATCGCCGGCC CCGTCTTCCT CCTCTTCCTT 
ATCATTATCA TCGTCTTCCT GGTCATCAAC TATCACCAGC GTGTCTACCA TAACCGCCAG 
AGGTTGGACA TGGAGGACCC CTCTTGCGAG ATGTGTCTCT CCAAAGACAA GACGCTCCAG 
GATCTCGTCT ACGACCTCTC CACGTCAGGG TCTGGCTCAG GGTTACCCCT TTTTGTCCAG 
CGCACAGTGG CCCGAACCAT TGTTTTACAA GAGATTATCG GCAAGGGCCG GTTCGGGGAA 
GTATGGCGTG GTCGCTGGAG GGGTGGTGAC GTGGCTGTGA AAATCTTCTC TTCTCGTGAA 
GAACGGTCTT GGTTCCGTGA AGCAGAGATC TACCAGACCG TCATGCTGCG CCATGAAAAC 
ATCCTTGGCT TTATTGCTGC TGACAATAAA GATAATGGCA CCTGGACCCA GCTGTGGCTT 
GTCTCTGACT ATCACGAGCA TGGCTCACTG TTTGATTATC TGAACCGCTA CACAGTGACC 
ATTGAGGGAA TGATTAAGCT AGCCTTGTCT GCAGCCAGTG GTTTGGCACA CCTGCATATG 
GAGATTGTGG GCACTCAAGG GAAGCCGGGA ATTGCTCATC GAGACTTGAA GTCAAAGAAC 
ATCCTGGTGA AAAAAAATGG CATGTGTGCC ATTGCAGACC TGGGCCTGGC TGTCCGTCAT 
GATGCGGTCA CTGACACCAT AGACATTGCT CCAAATCAGA GGGTGGGGAC CAAACGATAC 
ATGGCTCCTG AAGTCCTTGA CGAGACAATC AACATGAAGC ACTTTGACTC CTTCAAATGT 
GCCGACATCT ATGCCCTCGG GCTTGTCTAC TGGGAGATTG CACGAAGATG CAATTCTGGA 
GGAGTCCATG AAGACTATCA ACTGCCGTAT TACGACTTAG TGCCCTCCGA CCCTTCCATT 
GAGGAGATGC GAAAGGTTGT ATGTGACCAG AAGCTACGGC CCAATGTCCC CAACTGGTGG 
CAGAGTTATG AGGCCTTGCG AGTGATGGGA AAGATGATGC GGGAGTGCTG GTACGCCAAT 
GGTGCTGCCC GTCTGACAGC TCTGCGCATC AAGAAGACTC TGTCCCAGCT AAGCGTGCAG 
GAAGATGTGA AGATTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_031421.1
CDS	74..1591
Translation	MAESAGASSFFPLVVLLLAGSGGSGPRGIQALLCACTSCLQTNYTCETDGACMVSIFNLDGVEHHVRTCIPKVELVPAGKPFYCLSSEDLRNTHCCYIDFCNKIDLRVPSGHLKEPAHPSMWGPVELVGIIAGPVFLLFLIIIIVFLVINYHQRVYHNRQRLDMEDPSCEMCLSKDKTLQDLVYDLSTSGSGSGLPLFVQRTVARTIVLQEIIGKGRFGEVWRGRWRGGDVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTIEGMIKLALSAASGLAHLHMEIVGTQGKPGIAHRDLKSKNILVKKNGMCAIADLGLAVRHDAVTDTIDIAPNQRVGTKRYMAPEVLDETINMKHFDSFKCADIYALGLVYWEIARRCNSGGVHEDYQLPYYDLVPSDPSIEEMRKVVCDQKLRPNVPNWWQSYEALRVMGKMMRECWYANGAARLTALRIKKTLSQLSVQEDVKI

Target ORF information:

RefSeq Version	NM_007395.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus activin A receptor, type 1B (Acvr1b), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007395.4

ORF Insert Sequence:

ATGGCGGAGT CGGCCGGAGC CTCCTCCTTC TTCCCCCTTG TTGTCCTCCT GCTCGCCGGC 
AGCGGCGGGT CCGGGCCCCG GGGGATCCAG GCTCTGCTGT GTGCGTGCAC CAGCTGCCTA 
CAGACCAACT ACACCTGTGA GACAGATGGG GCTTGCATGG TCTCCATCTT TAACCTGGAT 
GGCGTGGAGC ACCATGTACG TACCTGCATC CCCAAGGTGG AGCTGGTTCC TGCTGGAAAG 
CCCTTCTACT GCCTGAGTTC AGAGGATCTG CGCAACACAC ACTGCTGCTA TATTGACTTC 
TGCAACAAGA TTGACCTCAG GGTCCCCAGC GGACACCTCA AGGAGCCTGC GCACCCCTCC 
ATGTGGGGCC CTGTGGAGCT GGTCGGCATC ATCGCCGGCC CCGTCTTCCT CCTCTTCCTT 
ATCATTATCA TCGTCTTCCT GGTCATCAAC TATCACCAGC GTGTCTACCA TAACCGCCAG 
AGGTTGGACA TGGAGGACCC CTCTTGCGAG ATGTGTCTCT CCAAAGACAA GACGCTCCAG 
GATCTCGTCT ACGACCTCTC CACGTCAGGG TCTGGCTCAG GGTTACCCCT TTTTGTCCAG 
CGCACAGTGG CCCGAACCAT TGTTTTACAA GAGATTATCG GCAAGGGCCG GTTCGGGGAA 
GTATGGCGTG GTCGCTGGAG GGGTGGTGAC GTGGCTGTGA AAATCTTCTC TTCTCGTGAA 
GAACGGTCTT GGTTCCGTGA AGCAGAGATC TACCAGACCG TCATGCTGCG CCATGAAAAC 
ATCCTTGGCT TTATTGCTGC TGACAATAAA GATAATGGCA CCTGGACCCA GCTGTGGCTT 
GTCTCTGACT ATCACGAGCA TGGCTCACTG TTTGATTATC TGAACCGCTA CACAGTGACC 
ATTGAGGGAA TGATTAAGCT AGCCTTGTCT GCAGCCAGTG GTTTGGCACA CCTGCATATG 
GAGATTGTGG GCACTCAAGG GAAGCCGGGA ATTGCTCATC GAGACTTGAA GTCAAAGAAC 
ATCCTGGTGA AAAAAAATGG CATGTGTGCC ATTGCAGACC TGGGCCTGGC TGTCCGTCAT 
GATGCGGTCA CTGACACCAT AGACATTGCT CCAAATCAGA GGGTGGGGAC CAAACGATAC 
ATGGCTCCTG AAGTCCTTGA CGAGACAATC AACATGAAGC ACTTTGACTC CTTCAAATGT 
GCCGACATCT ATGCCCTCGG GCTTGTCTAC TGGGAGATTG CACGAAGATG CAATTCTGGA 
GGAGTCCATG AAGACTATCA ACTGCCGTAT TACGACTTAG TGCCCTCCGA CCCTTCCATT 
GAGGAGATGC GAAAGGTTGT ATGTGACCAG AAGCTACGGC CCAATGTCCC CAACTGGTGG 
CAGAGTTATG AGGCCTTGCG AGTGATGGGA AAGATGATGC GGGAGTGCTG GTACGCCAAT 
GGTGCTGCCC GTCTGACAGC TCTGCGCATC AAGAAGACTC TGTCCCAGCT AAGCGTGCAG 
GAAGATGTGA AGATTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System.
Gastroenterology(2017 Oct)
Memic F,Knoflach V,Morarach K,Sadler R,Laranjeira C,Hjerling-Leffler J,Sundstr?m E,Pachnis V,Marklund U

The crucial role of activin A/ALK4 pathway in the pathogenesis of Ang-II-induced atrial fibrosis and vulnerability to atrial fibrillation.
Basic research in cardiology112(4)47(2017 Jul)
Wang Q,Yu Y,Zhang P,Chen Y,Li C,Chen J,Wang Y,Li Y

Haplodeficiency of activin receptor-like kinase 4 alleviates myocardial infarction-induced cardiac fibrosis and preserves cardiac function.
Journal of molecular and cellular cardiology1051-11(2017 Apr)
Chen YH,Wang Q,Li CY,Hou JW,Chen XM,Zhou Q,Chen J,Wang YP,Li YG

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Acvr1b cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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