Gene Symbol | ACVR1B |
Entrez Gene ID | 91 |
Full Name | activin A receptor type 1B |
Synonyms | ACTRIB,ACVRLK4,ALK4,SKR2 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. This protein is a type I receptor which is essential for signaling. Mutations in this gene are associated with pituitary tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jun 2010]. |
Disorder MIM: | |
Disorder Html: | Pancreatic cancer, somatic (3) |