Slc15a4 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Slc15a4
Entrez Gene ID	100561
Full Name	solute carrier family 15, member 4
Synonyms	AA987064,AW742963,C130069N12Rik,PHT1,PTR4
General protein information	Preferred Names solute carrier family 15, member 4 Names solute carrier family 15 member 4 peptide transporter 4 peptide-histidine transporter 4 peptide/histidine transporter 1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 5 Map Location: 5\|5 G1.2

mRNA and Protein(s)

mRNA	Protein	Name
XM_006504271.2	XP_006504334.1	solute carrier family 15 member 4 isoform X1
XM_006504272.4	XP_006504335.1	solute carrier family 15 member 4 isoform X2
XM_006504272.3	XP_006504335.1	solute carrier family 15 member 4 isoform X2
NM_133895.1	NP_598656.1	solute carrier family 15 member 4
XM_006504271.3	XP_006504334.1	solute carrier family 15 member 4 isoform X1

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Slc15a4	NP_653359.1
Gallus gallus (chicken)	SLC15A4	XP_415099.3
Arabidopsis thaliana (thale cress)	AT2G02020	NP_178311.1
Canis lupus familiaris (dog)	SLC15A4	XP_852542.3
Mus musculus (house mouse)	Slc15a4	NP_598656.1
Danio rerio (zebrafish)	slc15a4	NP_957251.1
Arabidopsis thaliana (thale cress)	AT1G62200	NP_176411.2
Xenopus tropicalis (tropical clawed frog)	slc15a4	XP_002935336.2
Homo sapiens (human)	SLC15A4	NP_663623.1
	SLC15A4	XP_002798885.1
Pan troglodytes (chimpanzee)	SLC15A4	XP_001137177.2
Bos taurus (cattle)	SLC15A4	NP_001095397.2

Gene Ontology
Bibliography

Related articles in PubMed

Semi-Mechanistic Population Pharmacokinetic Modeling of L-Histidine Disposition and Brain Uptake in Wildtype and Pht1 Null Mice.
Wang XX, Li YB, Feng MR, Smith DE
Pharmaceutical research35(1)19(2018 01)

Lysosome biogenesis regulated by the amino-acid transporter SLC15A4 is critical for functional integrity of mast cells.
Kobayashi T, Tsutsui H, Shimabukuro-Demoto S, Yoshida-Sugitani R, Karyu H, Furuyama-Tanaka K, Ohshima D, Kato N, Okamura T, Toyama-Sorimachi N
International immunology29(12)551-566(2017 Dec)

Induction of Systemic Autoimmunity by a Xenobiotic Requires Endosomal TLR Trafficking and Signaling from the Late Endosome and Endolysosome but Not Type I IFN.
Pollard KM, Escalante GM, Huang H, Haraldsson KM, Hultman P, Christy JM, Pawar RD, Mayeux JM, Gonzalez-Quintial R, Baccala R, Beutler B, Theofilopoulos AN, Kono DH
Journal of immunology (Baltimore, Md. : 1950)199(11)3739-3747(2017 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Slc15a4 is required for intact function of TLR9-expressing cells and for effective antibody isotype switching to IgG2c.
Title: Slc15a4 function is required for intact class switch recombination to IgG2c in response to TLR9 stimulation.

SLC15A4-mediated optimization of the endolysosomal state is integral to a Toll-like receptor 7-triggered, mTOR-dependent interferon regulatory factor 7-type I interferon circuit that leads to autoantibody production.
Title: The histidine transporter SLC15A4 coordinates mTOR-dependent inflammatory responses and pathogenic antibody production.

We found marked changes in protein expression and functional activity of PhT1 and PepT2, the former predominating in adult and the latter in neonate
Title: Divergent developmental expression and function of the proton-coupled oligopeptide transporters PepT2 and PhT1 in regional brain slices of mouse and rat.

results demonstrate pDCs and the production of type I IFNs by these cells are critical contributors to the pathogenesis of lupus-like autoimmunity in these models. IRF8 and SLC15A4 may provide important targets for therapeutic intervention in human lupus
Title: Essential requirement for IRF8 and SLC15A4 implicates plasmacytoid dendritic cells in the pathogenesis of lupus.

the feeble mutation (Slc15a4) affecting Plasmacytoid dendritic cells is dispensable for immunity during an acute infection; however, data show that feeble mice failed to control a chronic infection
Title: Slc15a4, a gene required for pDC sensing of TLR ligands, is required to control persistent viral infection.

The following Slc15a4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Slc15a4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu36049	XM_006504272.4 Latest version!	Mus musculus solute carrier family 15, member 4 (Slc15a4), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OMu10322	NM_133895.1 Latest version!	Mus musculus solute carrier family 15, member 4 (Slc15a4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$335.30 $479.00
OMu36048	XM_006504271.3 Latest version!	Mus musculus solute carrier family 15, member 4 (Slc15a4), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
View Old Accession Versions >>
OMu36049	XM_006504272.3	Mus musculus solute carrier family 15, member 4 (Slc15a4), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OMu36048	XM_006504271.2	Mus musculus solute carrier family 15, member 4 (Slc15a4), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Slc15a4 ( XM_006504271.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006504334.1 Mus musculus solute carrier family 15, member 4 (Slc15a4), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu36048
Clone ID Related Accession (Same CDS sequence)	XM_006504271.2 , XM_006504271.3
Accession Version	XM_006504271.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1566bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	solute carrier family 15 member 4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006504271.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGGGCG AGCGGGCGCC GCTGTTGGGT TCGCGGCGTC CGGCAGTGTC GGCGGCGTCC 
GCGGTGTTCG CGGGGCGGCG TGCGGCGTGC GGGGCGGTGC TGTTGGCCGA GCTGCTGGAG 
CGCGCGGCCT TCTACGGCGT CACGGCCAAC CTGGTGCTGT TCCTGAATGG CGCGCCGTTC 
GACTGGGAGG GCGCGCAGGC CAGCCAGGCG CTGCTGCTCT TCATGGGCCT CACCTATCTG 
GGCTCGCCGT TCGGGGGCTG GCTCGCCGAC GCCCGCCTCG GCCGGGCCCG CGCCATCCTG 
CTCAGCCTGG CCCTCTACCT GCTGGGCCTG CTGGCCTTCC CGCTGCTGGC CGCGCCCCGC 
TCGCGCTCCT TCCTCTGCGG GGACCCGCGG CCCGAGCTCG TGCGCAACTG CTCGGCGCCC 
TTCCCCAACG GGTCAGCGTC GTGTCCCGAG AACGCCGCGC GCCGCTGTGC CCCCGCCACC 
TTCGCGGGGC TCGTGCTCGT GGGTCTCGGG GTGGCCACGG TCAAGGCCAA CATCACGCCC 
TTCGGCGCCG ATCAGGTTAA AGATCGAGGT CCAGAAGCCA CTCGGAGATT TTTCAATTGG 
TTTTACTGGA GCATTAATTT GGGAGCAATC CTGTCATTAG GAGGTATTGC CTATATTCAG 
CAGAATGTGA GCTTTTTCAC AGGCTACCTG ATTCCCACAG TCTGTGTGGC CATTGCTTTC 
CTGGTCTTCC TCTGTGGCCA GAGTGTCTTC ATCACCAAGC CTCCTGACGG CAGTGCCTTC 
ACTGACATGT TCAGAATTCT GACCTACAGT TGCTGCTCCC AGAGAGGAGG GCAGCGGAGA 
AGTGGTGAAG GCCTTGGAGT CTTTCAGCAA TCTTCTAAAC ACAGTCTGTT TGATTCATGT 
AAGATGTCGC GTGGAGGGCC GTTCACAGAG GACAAAGTGG AAGACGTGAA AGCCCTGGTC 
AAGATTGTGC CCGTGTTCTT GGCTCTGATT CCTTACTGGA CAGTGTATTT CCAAATGCAG 
ACCACATATG CTTTACAGAG TCTTCATTTG AAGATTCCAG AAATCTCAAG TATCACCACC 
ACCCATCACA CGCTGCCTGC AGCTTGGCTC ACCATGTTTG ATGCGGTGCT CATCCTCCTG 
CTCATCCCAC TGAAGGACAA GCTGGTGGAC CCGGTGCTGA GGAGACATGG CCTGCTCCCA 
TCCTCCCTGA AGAGGATTGC TGTGGGGATG TTCTTCGTCA TGTGCTCTGC CTTTGCTGCA 
GGAATCCTGG AGAGTAAAAG GCTGGACCTG GTAAAGGAGA AGACCATTAA CCAGACCATT 
GGTGGTGTGG TGTACCATGC TGCTGACTTG CCCATCTGGT GGCAGATCCC ACAGTATGTG 
CTCATTGGCA TCAGTGAGAT ATTTGCAAGT ATAGCAGGGA ACATCAACAG CTGCCACCTG 
CATTACTACT TCTTCCTGCT GGCCGCCATC CAGGGAGCTA CGCTGCTGCT CTTCCTCATT 
GTGTCTGTGA AGTACGACCG CCAGCGAGCC AGGACAGATG GGGGGCCAGC CAGCACGAGG 
ACCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006504334.1
CDS	283..1848
Translation	MEGERAPLLGSRRPAVSAASAVFAGRRAACGAVLLAELLERAAFYGVTANLVLFLNGAPFDWEGAQASQALLLFMGLTYLGSPFGGWLADARLGRARAILLSLALYLLGLLAFPLLAAPRSRSFLCGDPRPELVRNCSAPFPNGSASCPENAARRCAPATFAGLVLVGLGVATVKANITPFGADQVKDRGPEATRRFFNWFYWSINLGAILSLGGIAYIQQNVSFFTGYLIPTVCVAIAFLVFLCGQSVFITKPPDGSAFTDMFRILTYSCCSQRGGQRRSGEGLGVFQQSSKHSLFDSCKMSRGGPFTEDKVEDVKALVKIVPVFLALIPYWTVYFQMQTTYALQSLHLKIPEISSITTTHHTLPAAWLTMFDAVLILLLIPLKDKLVDPVLRRHGLLPSSLKRIAVGMFFVMCSAFAAGILESKRLDLVKEKTINQTIGGVVYHAADLPIWWQIPQYVLIGISEIFASIAGNINSCHLHYYFFLLAAIQGATLLLFLIVSVKYDRQRARTDGGPASTRT

Target ORF information:

RefSeq Version	XM_006504271.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus solute carrier family 15, member 4 (Slc15a4), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006504271.2

ORF Insert Sequence:

ATGGAGGGCG AGCGGGCGCC GCTGTTGGGT TCGCGGCGTC CGGCAGTGTC GGCGGCGTCC 
GCGGTGTTCG CGGGGCGGCG TGCGGCGTGC GGGGCGGTGC TGTTGGCCGA GCTGCTGGAG 
CGCGCGGCCT TCTACGGCGT CACGGCCAAC CTGGTGCTGT TCCTGAATGG CGCGCCGTTC 
GACTGGGAGG GCGCGCAGGC CAGCCAGGCG CTGCTGCTCT TCATGGGCCT CACCTATCTG 
GGCTCGCCGT TCGGGGGCTG GCTCGCCGAC GCCCGCCTCG GCCGGGCCCG CGCCATCCTG 
CTCAGCCTGG CCCTCTACCT GCTGGGCCTG CTGGCCTTCC CGCTGCTGGC CGCGCCCCGC 
TCGCGCTCCT TCCTCTGCGG GGACCCGCGG CCCGAGCTCG TGCGCAACTG CTCGGCGCCC 
TTCCCCAACG GGTCAGCGTC GTGTCCCGAG AACGCCGCGC GCCGCTGTGC CCCCGCCACC 
TTCGCGGGGC TCGTGCTCGT GGGTCTCGGG GTGGCCACGG TCAAGGCCAA CATCACGCCC 
TTCGGCGCCG ATCAGGTTAA AGATCGAGGT CCAGAAGCCA CTCGGAGATT TTTCAATTGG 
TTTTACTGGA GCATTAATTT GGGAGCAATC CTGTCATTAG GAGGTATTGC CTATATTCAG 
CAGAATGTGA GCTTTTTCAC AGGCTACCTG ATTCCCACAG TCTGTGTGGC CATTGCTTTC 
CTGGTCTTCC TCTGTGGCCA GAGTGTCTTC ATCACCAAGC CTCCTGACGG CAGTGCCTTC 
ACTGACATGT TCAGAATTCT GACCTACAGT TGCTGCTCCC AGAGAGGAGG GCAGCGGAGA 
AGTGGTGAAG GCCTTGGAGT CTTTCAGCAA TCTTCTAAAC ACAGTCTGTT TGATTCATGT 
AAGATGTCGC GTGGAGGGCC GTTCACAGAG GACAAAGTGG AAGACGTGAA AGCCCTGGTC 
AAGATTGTGC CCGTGTTCTT GGCTCTGATT CCTTACTGGA CAGTGTATTT CCAAATGCAG 
ACCACATATG CTTTACAGAG TCTTCATTTG AAGATTCCAG AAATCTCAAG TATCACCACC 
ACCCATCACA CGCTGCCTGC AGCTTGGCTC ACCATGTTTG ATGCGGTGCT CATCCTCCTG 
CTCATCCCAC TGAAGGACAA GCTGGTGGAC CCGGTGCTGA GGAGACATGG CCTGCTCCCA 
TCCTCCCTGA AGAGGATTGC TGTGGGGATG TTCTTCGTCA TGTGCTCTGC CTTTGCTGCA 
GGAATCCTGG AGAGTAAAAG GCTGGACCTG GTAAAGGAGA AGACCATTAA CCAGACCATT 
GGTGGTGTGG TGTACCATGC TGCTGACTTG CCCATCTGGT GGCAGATCCC ACAGTATGTG 
CTCATTGGCA TCAGTGAGAT ATTTGCAAGT ATAGCAGGGA ACATCAACAG CTGCCACCTG 
CATTACTACT TCTTCCTGCT GGCCGCCATC CAGGGAGCTA CGCTGCTGCT CTTCCTCATT 
GTGTCTGTGA AGTACGACCG CCAGCGAGCC AGGACAGATG GGGGGCCAGC CAGCACGAGG 
ACCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Slc15a4 ( XM_006504272.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006504335.1 Mus musculus solute carrier family 15, member 4 (Slc15a4), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu36049
Clone ID Related Accession (Same CDS sequence)	XM_006504272.4 , XM_006504272.3
Accession Version	XM_006504272.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1218bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	solute carrier family 15 member 4 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006504272.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACCCGC CTTCCCTGCC TTGTCCTGGC TCCAGGCTTC CGTCCCAGGT TAAAGATCGA 
GGTCCAGAAG CCACTCGGAG ATTTTTCAAT TGGTTTTACT GGAGCATTAA TTTGGGAGCA 
ATCCTGTCAT TAGGAGGTAT TGCCTATATT CAGCAGAATG TGAGCTTTTT CACAGGCTAC 
CTGATTCCCA CAGTCTGTGT GGCCATTGCT TTCCTGGTCT TCCTCTGTGG CCAGAGTGTC 
TTCATCACCA AGCCTCCTGA CGGCAGTGCC TTCACTGACA TGTTCAGAAT TCTGACCTAC 
AGTTGCTGCT CCCAGAGAGG AGGGCAGCGG AGAAGTGGTG AAGGCCTTGG AGTCTTTCAG 
CAATCTTCTA AACACAGTCT GTTTGATTCA TGTAAGATGT CGCGTGGAGG GCCGTTCACA 
GAGGACAAAG TGGAAGACGT GAAAGCCCTG GTCAAGATTG TGCCCGTGTT CTTGGCTCTG 
ATTCCTTACT GGACAGTGTA TTTCCAAATG CAGACCACAT ATGCTTTACA GAGTCTTCAT 
TTGAAGATTC CAGAAATCTC AAGTATCACC ACCACCCATC ACACGCTGCC TGCAGCTTGG 
CTCACCATGT TTGATGCGGT GCTCATCCTC CTGCTCATCC CACTGAAGGA CAAGCTGGTG 
GACCCGGTGC TGAGGAGACA TGGCCTGCTC CCATCCTCCC TGAAGAGGAT TGCTGTGGGG 
ATGTTCTTCG TCATGTGCTC TGCCTTTGCT GCAGGAATCC TGGAGAGTAA AAGGCTGGAC 
CTGGTAAAGG AGAAGACCAT TAACCAGACC ATTGGTGGTG TGGTGTACCA TGCTGCTGAC 
TTGCCCATCT GGTGGCAGAT CCCACAGTAT GTGCTCATTG GCATCAGTGA GATATTTGCA 
AGTATAGCAG GTCTGGAATT TGCATACTCA GCTGCCCCCA AGTCCATGCA GAGCGCCATC 
ATGGGACTCT TCTTCTTCTT CTCTGGCATT GGGTCCTTTG TGGGCTCAGG ACTGTTGGCC 
CTGGTGTCTC TCAAGGCCAT TGGGTGGATG AGCAGTCATA CAGATTTTGG GAACATCAAC 
AGCTGCCACC TGCATTACTA CTTCTTCCTG CTGGCCGCCA TCCAGGGAGC TACGCTGCTG 
CTCTTCCTCA TTGTGTCTGT GAAGTACGAC CGCCAGCGAG CCAGGACAGA TGGGGGGCCA 
GCCAGCACGA GGACCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006504335.1
CDS	20..1237
Translation	MDPPSLPCPGSRLPSQVKDRGPEATRRFFNWFYWSINLGAILSLGGIAYIQQNVSFFTGYLIPTVCVAIAFLVFLCGQSVFITKPPDGSAFTDMFRILTYSCCSQRGGQRRSGEGLGVFQQSSKHSLFDSCKMSRGGPFTEDKVEDVKALVKIVPVFLALIPYWTVYFQMQTTYALQSLHLKIPEISSITTTHHTLPAAWLTMFDAVLILLLIPLKDKLVDPVLRRHGLLPSSLKRIAVGMFFVMCSAFAAGILESKRLDLVKEKTINQTIGGVVYHAADLPIWWQIPQYVLIGISEIFASIAGLEFAYSAAPKSMQSAIMGLFFFFSGIGSFVGSGLLALVSLKAIGWMSSHTDFGNINSCHLHYYFFLLAAIQGATLLLFLIVSVKYDRQRARTDGGPASTRT

Target ORF information:

RefSeq Version	XM_006504272.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus solute carrier family 15, member 4 (Slc15a4), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006504272.3

ORF Insert Sequence:

ATGGACCCGC CTTCCCTGCC TTGTCCTGGC TCCAGGCTTC CGTCCCAGGT TAAAGATCGA 
GGTCCAGAAG CCACTCGGAG ATTTTTCAAT TGGTTTTACT GGAGCATTAA TTTGGGAGCA 
ATCCTGTCAT TAGGAGGTAT TGCCTATATT CAGCAGAATG TGAGCTTTTT CACAGGCTAC 
CTGATTCCCA CAGTCTGTGT GGCCATTGCT TTCCTGGTCT TCCTCTGTGG CCAGAGTGTC 
TTCATCACCA AGCCTCCTGA CGGCAGTGCC TTCACTGACA TGTTCAGAAT TCTGACCTAC 
AGTTGCTGCT CCCAGAGAGG AGGGCAGCGG AGAAGTGGTG AAGGCCTTGG AGTCTTTCAG 
CAATCTTCTA AACACAGTCT GTTTGATTCA TGTAAGATGT CGCGTGGAGG GCCGTTCACA 
GAGGACAAAG TGGAAGACGT GAAAGCCCTG GTCAAGATTG TGCCCGTGTT CTTGGCTCTG 
ATTCCTTACT GGACAGTGTA TTTCCAAATG CAGACCACAT ATGCTTTACA GAGTCTTCAT 
TTGAAGATTC CAGAAATCTC AAGTATCACC ACCACCCATC ACACGCTGCC TGCAGCTTGG 
CTCACCATGT TTGATGCGGT GCTCATCCTC CTGCTCATCC CACTGAAGGA CAAGCTGGTG 
GACCCGGTGC TGAGGAGACA TGGCCTGCTC CCATCCTCCC TGAAGAGGAT TGCTGTGGGG 
ATGTTCTTCG TCATGTGCTC TGCCTTTGCT GCAGGAATCC TGGAGAGTAA AAGGCTGGAC 
CTGGTAAAGG AGAAGACCAT TAACCAGACC ATTGGTGGTG TGGTGTACCA TGCTGCTGAC 
TTGCCCATCT GGTGGCAGAT CCCACAGTAT GTGCTCATTG GCATCAGTGA GATATTTGCA 
AGTATAGCAG GTCTGGAATT TGCATACTCA GCTGCCCCCA AGTCCATGCA GAGCGCCATC 
ATGGGACTCT TCTTCTTCTT CTCTGGCATT GGGTCCTTTG TGGGCTCAGG ACTGTTGGCC 
CTGGTGTCTC TCAAGGCCAT TGGGTGGATG AGCAGTCATA CAGATTTTGG GAACATCAAC 
AGCTGCCACC TGCATTACTA CTTCTTCCTG CTGGCCGCCA TCCAGGGAGC TACGCTGCTG 
CTCTTCCTCA TTGTGTCTGT GAAGTACGAC CGCCAGCGAG CCAGGACAGA TGGGGGGCCA 
GCCAGCACGA GGACCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Slc15a4 ( XM_006504272.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006504335.1 Mus musculus solute carrier family 15, member 4 (Slc15a4), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu36049
Clone ID Related Accession (Same CDS sequence)	XM_006504272.4 , XM_006504272.3
Accession Version	XM_006504272.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1218bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	solute carrier family 15 member 4 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006504272.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACCCGC CTTCCCTGCC TTGTCCTGGC TCCAGGCTTC CGTCCCAGGT TAAAGATCGA 
GGTCCAGAAG CCACTCGGAG ATTTTTCAAT TGGTTTTACT GGAGCATTAA TTTGGGAGCA 
ATCCTGTCAT TAGGAGGTAT TGCCTATATT CAGCAGAATG TGAGCTTTTT CACAGGCTAC 
CTGATTCCCA CAGTCTGTGT GGCCATTGCT TTCCTGGTCT TCCTCTGTGG CCAGAGTGTC 
TTCATCACCA AGCCTCCTGA CGGCAGTGCC TTCACTGACA TGTTCAGAAT TCTGACCTAC 
AGTTGCTGCT CCCAGAGAGG AGGGCAGCGG AGAAGTGGTG AAGGCCTTGG AGTCTTTCAG 
CAATCTTCTA AACACAGTCT GTTTGATTCA TGTAAGATGT CGCGTGGAGG GCCGTTCACA 
GAGGACAAAG TGGAAGACGT GAAAGCCCTG GTCAAGATTG TGCCCGTGTT CTTGGCTCTG 
ATTCCTTACT GGACAGTGTA TTTCCAAATG CAGACCACAT ATGCTTTACA GAGTCTTCAT 
TTGAAGATTC CAGAAATCTC AAGTATCACC ACCACCCATC ACACGCTGCC TGCAGCTTGG 
CTCACCATGT TTGATGCGGT GCTCATCCTC CTGCTCATCC CACTGAAGGA CAAGCTGGTG 
GACCCGGTGC TGAGGAGACA TGGCCTGCTC CCATCCTCCC TGAAGAGGAT TGCTGTGGGG 
ATGTTCTTCG TCATGTGCTC TGCCTTTGCT GCAGGAATCC TGGAGAGTAA AAGGCTGGAC 
CTGGTAAAGG AGAAGACCAT TAACCAGACC ATTGGTGGTG TGGTGTACCA TGCTGCTGAC 
TTGCCCATCT GGTGGCAGAT CCCACAGTAT GTGCTCATTG GCATCAGTGA GATATTTGCA 
AGTATAGCAG GTCTGGAATT TGCATACTCA GCTGCCCCCA AGTCCATGCA GAGCGCCATC 
ATGGGACTCT TCTTCTTCTT CTCTGGCATT GGGTCCTTTG TGGGCTCAGG ACTGTTGGCC 
CTGGTGTCTC TCAAGGCCAT TGGGTGGATG AGCAGTCATA CAGATTTTGG GAACATCAAC 
AGCTGCCACC TGCATTACTA CTTCTTCCTG CTGGCCGCCA TCCAGGGAGC TACGCTGCTG 
CTCTTCCTCA TTGTGTCTGT GAAGTACGAC CGCCAGCGAG CCAGGACAGA TGGGGGGCCA 
GCCAGCACGA GGACCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006504335.1
CDS	162..1379
Translation	MDPPSLPCPGSRLPSQVKDRGPEATRRFFNWFYWSINLGAILSLGGIAYIQQNVSFFTGYLIPTVCVAIAFLVFLCGQSVFITKPPDGSAFTDMFRILTYSCCSQRGGQRRSGEGLGVFQQSSKHSLFDSCKMSRGGPFTEDKVEDVKALVKIVPVFLALIPYWTVYFQMQTTYALQSLHLKIPEISSITTTHHTLPAAWLTMFDAVLILLLIPLKDKLVDPVLRRHGLLPSSLKRIAVGMFFVMCSAFAAGILESKRLDLVKEKTINQTIGGVVYHAADLPIWWQIPQYVLIGISEIFASIAGLEFAYSAAPKSMQSAIMGLFFFFSGIGSFVGSGLLALVSLKAIGWMSSHTDFGNINSCHLHYYFFLLAAIQGATLLLFLIVSVKYDRQRARTDGGPASTRT

Target ORF information:

RefSeq Version	XM_006504272.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus solute carrier family 15, member 4 (Slc15a4), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006504272.4

ORF Insert Sequence:

ATGGACCCGC CTTCCCTGCC TTGTCCTGGC TCCAGGCTTC CGTCCCAGGT TAAAGATCGA 
GGTCCAGAAG CCACTCGGAG ATTTTTCAAT TGGTTTTACT GGAGCATTAA TTTGGGAGCA 
ATCCTGTCAT TAGGAGGTAT TGCCTATATT CAGCAGAATG TGAGCTTTTT CACAGGCTAC 
CTGATTCCCA CAGTCTGTGT GGCCATTGCT TTCCTGGTCT TCCTCTGTGG CCAGAGTGTC 
TTCATCACCA AGCCTCCTGA CGGCAGTGCC TTCACTGACA TGTTCAGAAT TCTGACCTAC 
AGTTGCTGCT CCCAGAGAGG AGGGCAGCGG AGAAGTGGTG AAGGCCTTGG AGTCTTTCAG 
CAATCTTCTA AACACAGTCT GTTTGATTCA TGTAAGATGT CGCGTGGAGG GCCGTTCACA 
GAGGACAAAG TGGAAGACGT GAAAGCCCTG GTCAAGATTG TGCCCGTGTT CTTGGCTCTG 
ATTCCTTACT GGACAGTGTA TTTCCAAATG CAGACCACAT ATGCTTTACA GAGTCTTCAT 
TTGAAGATTC CAGAAATCTC AAGTATCACC ACCACCCATC ACACGCTGCC TGCAGCTTGG 
CTCACCATGT TTGATGCGGT GCTCATCCTC CTGCTCATCC CACTGAAGGA CAAGCTGGTG 
GACCCGGTGC TGAGGAGACA TGGCCTGCTC CCATCCTCCC TGAAGAGGAT TGCTGTGGGG 
ATGTTCTTCG TCATGTGCTC TGCCTTTGCT GCAGGAATCC TGGAGAGTAA AAGGCTGGAC 
CTGGTAAAGG AGAAGACCAT TAACCAGACC ATTGGTGGTG TGGTGTACCA TGCTGCTGAC 
TTGCCCATCT GGTGGCAGAT CCCACAGTAT GTGCTCATTG GCATCAGTGA GATATTTGCA 
AGTATAGCAG GTCTGGAATT TGCATACTCA GCTGCCCCCA AGTCCATGCA GAGCGCCATC 
ATGGGACTCT TCTTCTTCTT CTCTGGCATT GGGTCCTTTG TGGGCTCAGG ACTGTTGGCC 
CTGGTGTCTC TCAAGGCCAT TGGGTGGATG AGCAGTCATA CAGATTTTGG GAACATCAAC 
AGCTGCCACC TGCATTACTA CTTCTTCCTG CTGGCCGCCA TCCAGGGAGC TACGCTGCTG 
CTCTTCCTCA TTGTGTCTGT GAAGTACGAC CGCCAGCGAG CCAGGACAGA TGGGGGGCCA 
GCCAGCACGA GGACCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Slc15a4 ( NM_133895.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_598656.1 Mus musculus solute carrier family 15, member 4 (Slc15a4), mRNA.

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CloneID	OMu10322
Clone ID Related Accession (Same CDS sequence)	NM_133895.1
Accession Version	NM_133895.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1725bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-26
Organism	Mus musculus(house mouse)
Product	solute carrier family 15 member 4
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC016233.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC016233.1, AY050630.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164131, SAMN01164135 [ECO:0000348] ##Evidence-Data-END##

ATGGAGGGCG AGCGGGCGCC GCTGTTGGGT TCGCGGCGTC CGGCAGTGTC GGCGGCGTCC 
GCGGTGTTCG CGGGGCGGCG TGCGGCGTGC GGGGCGGTGC TGTTGGCCGA GCTGCTGGAG 
CGCGCGGCCT TCTACGGCGT CACGGCCAAC CTGGTGCTGT TCCTGAATGG CGCGCCGTTC 
GACTGGGAGG GCGCGCAGGC CAGCCAGGCG CTGCTGCTCT TCATGGGCCT CACCTATCTG 
GGCTCGCCGT TCGGGGGCTG GCTCGCCGAC GCCCGCCTCG GCCGGGCCCG CGCCATCCTG 
CTCAGCCTGG CCCTCTACCT GCTGGGCCTG CTGGCCTTCC CGCTGCTGGC CGCGCCCCGC 
TCGCGCTCCT TCCTCTGCGG GGACCCGCGG CCCGAGCTCG TGCGCAACTG CTCGGCGCCC 
TTCCCCAACG GGTCAGCGTC GTGTCCCGAG AACGCCGCGC GCCGCTGTGC CCCCGCCACC 
TTCGCGGGGC TCGTGCTCGT GGGTCTCGGG GTGGCCACGG TCAAGGCCAA CATCACGCCC 
TTCGGCGCCG ATCAGGTTAA AGATCGAGGT CCAGAAGCCA CTCGGAGATT TTTCAATTGG 
TTTTACTGGA GCATTAATTT GGGAGCAATC CTGTCATTAG GAGGTATTGC CTATATTCAG 
CAGAATGTGA GCTTTTTCAC AGGCTACCTG ATTCCCACAG TCTGTGTGGC CATTGCTTTC 
CTGGTCTTCC TCTGTGGCCA GAGTGTCTTC ATCACCAAGC CTCCTGACGG CAGTGCCTTC 
ACTGACATGT TCAGAATTCT GACCTACAGT TGCTGCTCCC AGAGAGGAGG GCAGCGGAGA 
AGTGGTGAAG GCCTTGGAGT CTTTCAGCAA TCTTCTAAAC ACAGTCTGTT TGATTCATGT 
AAGATGTCGC GTGGAGGGCC GTTCACAGAG GACAAAGTGG AAGACGTGAA AGCCCTGGTC 
AAGATTGTGC CCGTGTTCTT GGCTCTGATT CCTTACTGGA CAGTGTATTT CCAAATGCAG 
ACCACATATG CTTTACAGAG TCTTCATTTG AAGATTCCAG AAATCTCAAG TATCACCACC 
ACCCATCACA CGCTGCCTGC AGCTTGGCTC ACCATGTTTG ATGCGGTGCT CATCCTCCTG 
CTCATCCCAC TGAAGGACAA GCTGGTGGAC CCGGTGCTGA GGAGACATGG CCTGCTCCCA 
TCCTCCCTGA AGAGGATTGC TGTGGGGATG TTCTTCGTCA TGTGCTCTGC CTTTGCTGCA 
GGAATCCTGG AGAGTAAAAG GCTGGACCTG GTAAAGGAGA AGACCATTAA CCAGACCATT 
GGTGGTGTGG TGTACCATGC TGCTGACTTG CCCATCTGGT GGCAGATCCC ACAGTATGTG 
CTCATTGGCA TCAGTGAGAT ATTTGCAAGT ATAGCAGGTC TGGAATTTGC ATACTCAGCT 
GCCCCCAAGT CCATGCAGAG CGCCATCATG GGACTCTTCT TCTTCTTCTC TGGCATTGGG 
TCCTTTGTGG GCTCAGGACT GTTGGCCCTG GTGTCTCTCA AGGCCATTGG GTGGATGAGC 
AGTCATACAG ATTTTGGGAA CATCAACAGC TGCCACCTGC ATTACTACTT CTTCCTGCTG 
GCCGCCATCC AGGGAGCTAC GCTGCTGCTC TTCCTCATTG TGTCTGTGAA GTACGACCGC 
CAGCGAGCCA GGACAGATGG GGGGCCAGCC AGCACGAGGA CCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_598656.1
CDS	24..1748
Translation	MEGERAPLLGSRRPAVSAASAVFAGRRAACGAVLLAELLERAAFYGVTANLVLFLNGAPFDWEGAQASQALLLFMGLTYLGSPFGGWLADARLGRARAILLSLALYLLGLLAFPLLAAPRSRSFLCGDPRPELVRNCSAPFPNGSASCPENAARRCAPATFAGLVLVGLGVATVKANITPFGADQVKDRGPEATRRFFNWFYWSINLGAILSLGGIAYIQQNVSFFTGYLIPTVCVAIAFLVFLCGQSVFITKPPDGSAFTDMFRILTYSCCSQRGGQRRSGEGLGVFQQSSKHSLFDSCKMSRGGPFTEDKVEDVKALVKIVPVFLALIPYWTVYFQMQTTYALQSLHLKIPEISSITTTHHTLPAAWLTMFDAVLILLLIPLKDKLVDPVLRRHGLLPSSLKRIAVGMFFVMCSAFAAGILESKRLDLVKEKTINQTIGGVVYHAADLPIWWQIPQYVLIGISEIFASIAGLEFAYSAAPKSMQSAIMGLFFFFSGIGSFVGSGLLALVSLKAIGWMSSHTDFGNINSCHLHYYFFLLAAIQGATLLLFLIVSVKYDRQRARTDGGPASTRT

Target ORF information:

RefSeq Version	NM_133895.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus solute carrier family 15, member 4 (Slc15a4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_133895.1

ORF Insert Sequence:

ATGGAGGGCG AGCGGGCGCC GCTGTTGGGT TCGCGGCGTC CGGCAGTGTC GGCGGCGTCC 
GCGGTGTTCG CGGGGCGGCG TGCGGCGTGC GGGGCGGTGC TGTTGGCCGA GCTGCTGGAG 
CGCGCGGCCT TCTACGGCGT CACGGCCAAC CTGGTGCTGT TCCTGAATGG CGCGCCGTTC 
GACTGGGAGG GCGCGCAGGC CAGCCAGGCG CTGCTGCTCT TCATGGGCCT CACCTATCTG 
GGCTCGCCGT TCGGGGGCTG GCTCGCCGAC GCCCGCCTCG GCCGGGCCCG CGCCATCCTG 
CTCAGCCTGG CCCTCTACCT GCTGGGCCTG CTGGCCTTCC CGCTGCTGGC CGCGCCCCGC 
TCGCGCTCCT TCCTCTGCGG GGACCCGCGG CCCGAGCTCG TGCGCAACTG CTCGGCGCCC 
TTCCCCAACG GGTCAGCGTC GTGTCCCGAG AACGCCGCGC GCCGCTGTGC CCCCGCCACC 
TTCGCGGGGC TCGTGCTCGT GGGTCTCGGG GTGGCCACGG TCAAGGCCAA CATCACGCCC 
TTCGGCGCCG ATCAGGTTAA AGATCGAGGT CCAGAAGCCA CTCGGAGATT TTTCAATTGG 
TTTTACTGGA GCATTAATTT GGGAGCAATC CTGTCATTAG GAGGTATTGC CTATATTCAG 
CAGAATGTGA GCTTTTTCAC AGGCTACCTG ATTCCCACAG TCTGTGTGGC CATTGCTTTC 
CTGGTCTTCC TCTGTGGCCA GAGTGTCTTC ATCACCAAGC CTCCTGACGG CAGTGCCTTC 
ACTGACATGT TCAGAATTCT GACCTACAGT TGCTGCTCCC AGAGAGGAGG GCAGCGGAGA 
AGTGGTGAAG GCCTTGGAGT CTTTCAGCAA TCTTCTAAAC ACAGTCTGTT TGATTCATGT 
AAGATGTCGC GTGGAGGGCC GTTCACAGAG GACAAAGTGG AAGACGTGAA AGCCCTGGTC 
AAGATTGTGC CCGTGTTCTT GGCTCTGATT CCTTACTGGA CAGTGTATTT CCAAATGCAG 
ACCACATATG CTTTACAGAG TCTTCATTTG AAGATTCCAG AAATCTCAAG TATCACCACC 
ACCCATCACA CGCTGCCTGC AGCTTGGCTC ACCATGTTTG ATGCGGTGCT CATCCTCCTG 
CTCATCCCAC TGAAGGACAA GCTGGTGGAC CCGGTGCTGA GGAGACATGG CCTGCTCCCA 
TCCTCCCTGA AGAGGATTGC TGTGGGGATG TTCTTCGTCA TGTGCTCTGC CTTTGCTGCA 
GGAATCCTGG AGAGTAAAAG GCTGGACCTG GTAAAGGAGA AGACCATTAA CCAGACCATT 
GGTGGTGTGG TGTACCATGC TGCTGACTTG CCCATCTGGT GGCAGATCCC ACAGTATGTG 
CTCATTGGCA TCAGTGAGAT ATTTGCAAGT ATAGCAGGTC TGGAATTTGC ATACTCAGCT 
GCCCCCAAGT CCATGCAGAG CGCCATCATG GGACTCTTCT TCTTCTTCTC TGGCATTGGG 
TCCTTTGTGG GCTCAGGACT GTTGGCCCTG GTGTCTCTCA AGGCCATTGG GTGGATGAGC 
AGTCATACAG ATTTTGGGAA CATCAACAGC TGCCACCTGC ATTACTACTT CTTCCTGCTG 
GCCGCCATCC AGGGAGCTAC GCTGCTGCTC TTCCTCATTG TGTCTGTGAA GTACGACCGC 
CAGCGAGCCA GGACAGATGG GGGGCCAGCC AGCACGAGGA CCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Slc15a4 ( XM_006504271.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006504334.1 Mus musculus solute carrier family 15, member 4 (Slc15a4), transcript variant X1, mRNA.

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CloneID	OMu36048
Clone ID Related Accession (Same CDS sequence)	XM_006504271.2 , XM_006504271.3
Accession Version	XM_006504271.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1566bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	solute carrier family 15 member 4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006504271.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGGGCG AGCGGGCGCC GCTGTTGGGT TCGCGGCGTC CGGCAGTGTC GGCGGCGTCC 
GCGGTGTTCG CGGGGCGGCG TGCGGCGTGC GGGGCGGTGC TGTTGGCCGA GCTGCTGGAG 
CGCGCGGCCT TCTACGGCGT CACGGCCAAC CTGGTGCTGT TCCTGAATGG CGCGCCGTTC 
GACTGGGAGG GCGCGCAGGC CAGCCAGGCG CTGCTGCTCT TCATGGGCCT CACCTATCTG 
GGCTCGCCGT TCGGGGGCTG GCTCGCCGAC GCCCGCCTCG GCCGGGCCCG CGCCATCCTG 
CTCAGCCTGG CCCTCTACCT GCTGGGCCTG CTGGCCTTCC CGCTGCTGGC CGCGCCCCGC 
TCGCGCTCCT TCCTCTGCGG GGACCCGCGG CCCGAGCTCG TGCGCAACTG CTCGGCGCCC 
TTCCCCAACG GGTCAGCGTC GTGTCCCGAG AACGCCGCGC GCCGCTGTGC CCCCGCCACC 
TTCGCGGGGC TCGTGCTCGT GGGTCTCGGG GTGGCCACGG TCAAGGCCAA CATCACGCCC 
TTCGGCGCCG ATCAGGTTAA AGATCGAGGT CCAGAAGCCA CTCGGAGATT TTTCAATTGG 
TTTTACTGGA GCATTAATTT GGGAGCAATC CTGTCATTAG GAGGTATTGC CTATATTCAG 
CAGAATGTGA GCTTTTTCAC AGGCTACCTG ATTCCCACAG TCTGTGTGGC CATTGCTTTC 
CTGGTCTTCC TCTGTGGCCA GAGTGTCTTC ATCACCAAGC CTCCTGACGG CAGTGCCTTC 
ACTGACATGT TCAGAATTCT GACCTACAGT TGCTGCTCCC AGAGAGGAGG GCAGCGGAGA 
AGTGGTGAAG GCCTTGGAGT CTTTCAGCAA TCTTCTAAAC ACAGTCTGTT TGATTCATGT 
AAGATGTCGC GTGGAGGGCC GTTCACAGAG GACAAAGTGG AAGACGTGAA AGCCCTGGTC 
AAGATTGTGC CCGTGTTCTT GGCTCTGATT CCTTACTGGA CAGTGTATTT CCAAATGCAG 
ACCACATATG CTTTACAGAG TCTTCATTTG AAGATTCCAG AAATCTCAAG TATCACCACC 
ACCCATCACA CGCTGCCTGC AGCTTGGCTC ACCATGTTTG ATGCGGTGCT CATCCTCCTG 
CTCATCCCAC TGAAGGACAA GCTGGTGGAC CCGGTGCTGA GGAGACATGG CCTGCTCCCA 
TCCTCCCTGA AGAGGATTGC TGTGGGGATG TTCTTCGTCA TGTGCTCTGC CTTTGCTGCA 
GGAATCCTGG AGAGTAAAAG GCTGGACCTG GTAAAGGAGA AGACCATTAA CCAGACCATT 
GGTGGTGTGG TGTACCATGC TGCTGACTTG CCCATCTGGT GGCAGATCCC ACAGTATGTG 
CTCATTGGCA TCAGTGAGAT ATTTGCAAGT ATAGCAGGGA ACATCAACAG CTGCCACCTG 
CATTACTACT TCTTCCTGCT GGCCGCCATC CAGGGAGCTA CGCTGCTGCT CTTCCTCATT 
GTGTCTGTGA AGTACGACCG CCAGCGAGCC AGGACAGATG GGGGGCCAGC CAGCACGAGG 
ACCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006504334.1
CDS	283..1848
Translation	MEGERAPLLGSRRPAVSAASAVFAGRRAACGAVLLAELLERAAFYGVTANLVLFLNGAPFDWEGAQASQALLLFMGLTYLGSPFGGWLADARLGRARAILLSLALYLLGLLAFPLLAAPRSRSFLCGDPRPELVRNCSAPFPNGSASCPENAARRCAPATFAGLVLVGLGVATVKANITPFGADQVKDRGPEATRRFFNWFYWSINLGAILSLGGIAYIQQNVSFFTGYLIPTVCVAIAFLVFLCGQSVFITKPPDGSAFTDMFRILTYSCCSQRGGQRRSGEGLGVFQQSSKHSLFDSCKMSRGGPFTEDKVEDVKALVKIVPVFLALIPYWTVYFQMQTTYALQSLHLKIPEISSITTTHHTLPAAWLTMFDAVLILLLIPLKDKLVDPVLRRHGLLPSSLKRIAVGMFFVMCSAFAAGILESKRLDLVKEKTINQTIGGVVYHAADLPIWWQIPQYVLIGISEIFASIAGNINSCHLHYYFFLLAAIQGATLLLFLIVSVKYDRQRARTDGGPASTRT

Target ORF information:

RefSeq Version	XM_006504271.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus solute carrier family 15, member 4 (Slc15a4), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006504271.3

ORF Insert Sequence:

ATGGAGGGCG AGCGGGCGCC GCTGTTGGGT TCGCGGCGTC CGGCAGTGTC GGCGGCGTCC 
GCGGTGTTCG CGGGGCGGCG TGCGGCGTGC GGGGCGGTGC TGTTGGCCGA GCTGCTGGAG 
CGCGCGGCCT TCTACGGCGT CACGGCCAAC CTGGTGCTGT TCCTGAATGG CGCGCCGTTC 
GACTGGGAGG GCGCGCAGGC CAGCCAGGCG CTGCTGCTCT TCATGGGCCT CACCTATCTG 
GGCTCGCCGT TCGGGGGCTG GCTCGCCGAC GCCCGCCTCG GCCGGGCCCG CGCCATCCTG 
CTCAGCCTGG CCCTCTACCT GCTGGGCCTG CTGGCCTTCC CGCTGCTGGC CGCGCCCCGC 
TCGCGCTCCT TCCTCTGCGG GGACCCGCGG CCCGAGCTCG TGCGCAACTG CTCGGCGCCC 
TTCCCCAACG GGTCAGCGTC GTGTCCCGAG AACGCCGCGC GCCGCTGTGC CCCCGCCACC 
TTCGCGGGGC TCGTGCTCGT GGGTCTCGGG GTGGCCACGG TCAAGGCCAA CATCACGCCC 
TTCGGCGCCG ATCAGGTTAA AGATCGAGGT CCAGAAGCCA CTCGGAGATT TTTCAATTGG 
TTTTACTGGA GCATTAATTT GGGAGCAATC CTGTCATTAG GAGGTATTGC CTATATTCAG 
CAGAATGTGA GCTTTTTCAC AGGCTACCTG ATTCCCACAG TCTGTGTGGC CATTGCTTTC 
CTGGTCTTCC TCTGTGGCCA GAGTGTCTTC ATCACCAAGC CTCCTGACGG CAGTGCCTTC 
ACTGACATGT TCAGAATTCT GACCTACAGT TGCTGCTCCC AGAGAGGAGG GCAGCGGAGA 
AGTGGTGAAG GCCTTGGAGT CTTTCAGCAA TCTTCTAAAC ACAGTCTGTT TGATTCATGT 
AAGATGTCGC GTGGAGGGCC GTTCACAGAG GACAAAGTGG AAGACGTGAA AGCCCTGGTC 
AAGATTGTGC CCGTGTTCTT GGCTCTGATT CCTTACTGGA CAGTGTATTT CCAAATGCAG 
ACCACATATG CTTTACAGAG TCTTCATTTG AAGATTCCAG AAATCTCAAG TATCACCACC 
ACCCATCACA CGCTGCCTGC AGCTTGGCTC ACCATGTTTG ATGCGGTGCT CATCCTCCTG 
CTCATCCCAC TGAAGGACAA GCTGGTGGAC CCGGTGCTGA GGAGACATGG CCTGCTCCCA 
TCCTCCCTGA AGAGGATTGC TGTGGGGATG TTCTTCGTCA TGTGCTCTGC CTTTGCTGCA 
GGAATCCTGG AGAGTAAAAG GCTGGACCTG GTAAAGGAGA AGACCATTAA CCAGACCATT 
GGTGGTGTGG TGTACCATGC TGCTGACTTG CCCATCTGGT GGCAGATCCC ACAGTATGTG 
CTCATTGGCA TCAGTGAGAT ATTTGCAAGT ATAGCAGGGA ACATCAACAG CTGCCACCTG 
CATTACTACT TCTTCCTGCT GGCCGCCATC CAGGGAGCTA CGCTGCTGCT CTTCCTCATT 
GTGTCTGTGA AGTACGACCG CCAGCGAGCC AGGACAGATG GGGGGCCAGC CAGCACGAGG 
ACCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Semi-Mechanistic Population Pharmacokinetic Modeling of L-Histidine Disposition and Brain Uptake in Wildtype and Pht1 Null Mice.
Pharmaceutical research35(1)19(2018 01)
Wang XX,Li YB,Feng MR,Smith DE

Lysosome biogenesis regulated by the amino-acid transporter SLC15A4 is critical for functional integrity of mast cells.
International immunology29(12)551-566(2017 Dec)
Kobayashi T,Tsutsui H,Shimabukuro-Demoto S,Yoshida-Sugitani R,Karyu H,Furuyama-Tanaka K,Ohshima D,Kato N,Okamura T,Toyama-Sorimachi N

Induction of Systemic Autoimmunity by a Xenobiotic Requires Endosomal TLR Trafficking and Signaling from the Late Endosome and Endolysosome but Not Type I IFN.
Journal of immunology (Baltimore, Md. : 1950)199(11)3739-3747(2017 Dec)
Pollard KM,Escalante GM,Huang H,Haraldsson KM,Hultman P,Christy JM,Pawar RD,Mayeux JM,Gonzalez-Quintial R,Baccala R,Beutler B,Theofilopoulos AN,Kono DH

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Slc15a4 cDNA ORF clone, Mus musculus(house mouse)

Gene

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gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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