RIMS3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	RIMS3
Entrez Gene ID	9783
Full Name	regulating synaptic membrane exocytosis 3
Synonyms	NIM3,RIM3
General protein information	Preferred Names regulating synaptic membrane exocytosis 3 Names regulating synaptic membrane exocytosis protein 3 RIM 3 RIM3 gamma Rab-3 interacting molecule 3 rab-3-interacting molecule 3
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1p34.2
Disorder MIM:	611600

mRNA and Protein(s)

mRNA	Protein	Name
NM_014747.2	NP_055562.2	regulating synaptic membrane exocytosis protein 3
XM_011542480.1	XP_011540782.1	regulating synaptic membrane exocytosis protein 3 isoform X1
XM_011542479.2	XP_011540781.1	regulating synaptic membrane exocytosis protein 3 isoform X1
NM_014747.3	NP_055562.2	regulating synaptic membrane exocytosis protein 3

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Rims3	NP_891559.1
Canis lupus familiaris (dog)	RIMS3	XP_005628929.1
Danio rerio (zebrafish)	rims3	NP_001093479.1
Pan troglodytes (chimpanzee)	RIMS3	XP_003308066.1
Rattus norvegicus (Norway rat)	Rims3	NP_075220.1
Gallus gallus (chicken)	RIMS3	XP_004947844.1
Xenopus tropicalis (tropical clawed frog)	rims3	NP_001072491.1
Homo sapiens (human)	RIMS3	NP_055562.2
	RIMS3	XP_001084240.1
Bos taurus (cattle)	RIMS3	NP_001192796.1

Gene Ontology
Bibliography

Related articles in PubMed

Genome-Wide Detection of Copy Number Variations in Unsolved Inherited Retinal Disease.
Huang XF, Mao JY, Huang ZQ, Rao FQ, Cheng FF, Li FF, Wang QF, Jin ZB
Investigative ophthalmology & visual science58(1)424-429(2017 01)

Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism.
Corominas R, Yang X, Lin GN, Kang S, Shen Y, Ghamsari L, Broly M, Rodriguez M, Tam S, Trigg SA, Fan C, Yi S, Tasan M, Lemmens I, Kuang X, Zhao N, Malhotra D, Michaelson JJ, Vacic V, Calderwood MA, Roth FP, Tavernier J, Horvath S, Salehi-Ashtiani K, Korkin D, Sebat J, Hill DE, Hao T, Vidal M, Iakoucheva LM
Nature communications53650(2014 Apr)

Image-based genome-wide siRNA screen identifies selective autophagy factors.
Orvedahl A, Sumpter R Jr, Xiao G, Ng A, Zou Z, Tang Y, Narimatsu M, Gilpin C, Sun Q, Roth M, Forst CV, Wrana JL, Zhang YE, Luby-Phelps K, Xavier RJ, Xie Y, Levine B
Nature480(7375)113-7(2011 Dec)

A de novo 1p34.2 microdeletion identifies the synaptic vesicle gene RIMS3 as a novel candidate for autism.
Kumar RA, Sudi J, Babatz TD, Brune CW, Oswald D, Yen M, Nowak NJ, Cook EH, Christian SL, Dobyns WB
Journal of medical genetics47(2)81-90(2010 Feb)

Investigation of the expression of genes affecting cytomatrix active zone function in the amygdala in schizophrenia: effects of antipsychotic drugs.
Weidenhofer J, Scott RJ, Tooney PA
Journal of psychiatric research43(3)282-90(2009 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

We identified four novel CNVs in three different genes (one duplication in USH2A gene, two duplications in CEP290 gene, and one duplication in RIMS2 gene) in total four families, at a detection rate of 8% (4/50).
Title: Genome-Wide Detection of Copy Number Variations in Unsolved Inherited Retinal Disease.

Observational study of gene-disease association. (HuGE Navigator)
Title: A de novo 1p34.2 microdeletion identifies the synaptic vesicle gene RIMS3 as a novel candidate for autism.

Western blot analysis shows increased piccolo protein expression in the amygdala in schizophrenia.
Title: Investigation of the expression of genes affecting cytomatrix active zone function in the amygdala in schizophrenia: effects of antipsychotic drugs.

The following RIMS3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RIMS3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu18397	NM_014747.3 Latest version!	Homo sapiens regulating synaptic membrane exocytosis 3 (RIMS3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu18397	XM_011542480.1 Latest version!	Homo sapiens regulating synaptic membrane exocytosis 3 (RIMS3), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu63294	XM_011542479.2 Latest version!	Homo sapiens regulating synaptic membrane exocytosis 3 (RIMS3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
View Old Accession Versions >>
OHu18397	NM_014747.2	Homo sapiens regulating synaptic membrane exocytosis 3 (RIMS3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

RIMS3 ( NM_014747.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_055562.2 Homo sapiens regulating synaptic membrane exocytosis 3 (RIMS3), mRNA.

Price & Availability↑

CloneID	OHu18397
Clone ID Related Accession (Same CDS sequence)	NM_014747.2 , XM_011542480.1 , NM_014747.3
Accession Version	NM_014747.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 927bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-30
Organism	Homo sapiens(human)
Product	regulating synaptic membrane exocytosis protein 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from D87074.1, BC003103.1 and CK005853.1. On or before Aug 30, 2004 this sequence version replaced XM_375720.2, NM_014747.1. ##Evidence-Data-START## Transcript exon combination :: D87074.1, SRR1803614.173700.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

ATGTTTAACG GGGAGCCAGG TCCTGCCTCA TCTGGGGCCT CCAGGAATGT GGTGCGGAGC 
TCCAGCATTA GCGGTGAAAT CTGCGGATCC CAGCAAGCCG GGGGCGGGGC TGGGACCACC 
ACCGCCAAGA AGCGGCGGAG CAGCCTGGGT GCCAAGATGG TGGCCATCGT GGGCCTGACT 
CAGTGGAGCA AGAGCACACT CCAGCTTCCG CAGCCTGAAG GGGCCACCAA GAAGCTGCGC 
AGCAACATCC GCCGGAGCAC GGAGACAGGC ATCGCGGTGG AGATGCGGAG CCGGGTCACA 
CGCCAGGGCA GCCGGGAGTC CACCGATGGG AGCACCAACA GCAACAGCTC CGACGGCACG 
TTCATCTTCC CCACTACCCG GCTAGGGGCT GAAAGCCAGT TCAGCGATTT CCTGGATGGG 
CTGGGACCAG CTCAGATTGT GGGGCGACAG ACACTGGCAA CACCACCCAT GGGAGATGTG 
CACATTGCCA TCATGGACCG GAGTGGCCAG CTGGAGGTGG AAGTGATTGA AGCTCGGGGC 
CTGACCCCCA AACCAGGCTC CAAATCCCTC CCAGCCACCT ATATCAAGGT TTACCTGCTG 
GAGAATGGGG CCTGCTTGGC CAAGAAGAAG ACAAAGATGA CCAAGAAGAC CTGTGATCCC 
CTGTACCAGC AGGCTCTGCT CTTTGACGAG GGACCCCAGG GCAAGGTGCT GCAGGTGATC 
GTCTGGGGAG ACTATGGCCG CATGGACCAC AAGTGCTTCA TGGGCATGGC CCAGATCATG 
CTGGACGAGC TGGACCTCAG CGCCGCGGTC ACCGGCTGGT ACAAACTCTT CCCCACCTCC 
TCAGTGGCAG ACTCCACACT CGGATCCCTC ACCAGGCGCC TGTCCCAGTC TTCCCTGGAG 
AGTGCCACCA GCCCCTCATG CTCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055562.2
CDS	470..1396
Translation	MFNGEPGPASSGASRNVVRSSSISGEICGSQQAGGGAGTTTAKKRRSSLGAKMVAIVGLTQWSKSTLQLPQPEGATKKLRSNIRRSTETGIAVEMRSRVTRQGSRESTDGSTNSNSSDGTFIFPTTRLGAESQFSDFLDGLGPAQIVGRQTLATPPMGDVHIAIMDRSGQLEVEVIEARGLTPKPGSKSLPATYIKVYLLENGACLAKKKTKMTKKTCDPLYQQALLFDEGPQGKVLQVIVWGDYGRMDHKCFMGMAQIMLDELDLSAAVTGWYKLFPTSSVADSTLGSLTRRLSQSSLESATSPSCS

Target ORF information:

RefSeq Version	NM_014747.2
Organism	Homo sapiens(human)
Definition	Homo sapiens regulating synaptic membrane exocytosis 3 (RIMS3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014747.2

ORF Insert Sequence:

ATGTTTAACG GGGAGCCAGG TCCTGCCTCA TCTGGGGCCT CCAGGAATGT GGTGCGGAGC 
TCCAGCATTA GCGGTGAAAT CTGCGGATCC CAGCAAGCCG GGGGCGGGGC TGGGACCACC 
ACCGCCAAGA AGCGGCGGAG CAGCCTGGGT GCCAAGATGG TGGCCATCGT GGGCCTGACT 
CAGTGGAGCA AGAGCACACT CCAGCTTCCG CAGCCTGAAG GGGCCACCAA GAAGCTGCGC 
AGCAACATCC GCCGGAGCAC GGAGACAGGC ATCGCGGTGG AGATGCGGAG CCGGGTCACA 
CGCCAGGGCA GCCGGGAGTC CACCGATGGG AGCACCAACA GCAACAGCTC CGACGGCACG 
TTCATCTTCC CCACTACCCG GCTAGGGGCT GAAAGCCAGT TCAGCGATTT CCTGGATGGG 
CTGGGACCAG CTCAGATTGT GGGGCGACAG ACACTGGCAA CACCACCCAT GGGAGATGTG 
CACATTGCCA TCATGGACCG GAGTGGCCAG CTGGAGGTGG AAGTGATTGA AGCTCGGGGC 
CTGACCCCCA AACCAGGCTC CAAATCCCTC CCAGCCACCT ATATCAAGGT TTACCTGCTG 
GAGAATGGGG CCTGCTTGGC CAAGAAGAAG ACAAAGATGA CCAAGAAGAC CTGTGATCCC 
CTGTACCAGC AGGCTCTGCT CTTTGACGAG GGACCCCAGG GCAAGGTGCT GCAGGTGATC 
GTCTGGGGAG ACTATGGCCG CATGGACCAC AAGTGCTTCA TGGGCATGGC CCAGATCATG 
CTGGACGAGC TGGACCTCAG CGCCGCGGTC ACCGGCTGGT ACAAACTCTT CCCCACCTCC 
TCAGTGGCAG ACTCCACACT CGGATCCCTC ACCAGGCGCC TGTCCCAGTC TTCCCTGGAG 
AGTGCCACCA GCCCCTCATG CTCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RIMS3 ( NM_014747.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_055562.2 Homo sapiens regulating synaptic membrane exocytosis 3 (RIMS3), mRNA.

Price & Availability↑

CloneID	OHu18397
Clone ID Related Accession (Same CDS sequence)	NM_014747.2 , XM_011542480.1 , NM_014747.3
Accession Version	NM_014747.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 927bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-25
Organism	Homo sapiens(human)
Product	regulating synaptic membrane exocytosis protein 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL031289.1. On Aug 18, 2018 this sequence version replaced NM_014747.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: D87074.1, SRR1803614.173700.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000372684.8/ ENSP00000361769.3 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END##

ATGTTTAACG GGGAGCCAGG TCCTGCCTCA TCTGGGGCCT CCAGGAATGT GGTGCGGAGC 
TCCAGCATTA GCGGTGAAAT CTGCGGATCC CAGCAAGCCG GGGGCGGGGC TGGGACCACC 
ACCGCCAAGA AGCGGCGGAG CAGCCTGGGT GCCAAGATGG TGGCCATCGT GGGCCTGACT 
CAGTGGAGCA AGAGCACACT CCAGCTTCCG CAGCCTGAAG GGGCCACCAA GAAGCTGCGC 
AGCAACATCC GCCGGAGCAC GGAGACAGGC ATCGCGGTGG AGATGCGGAG CCGGGTCACA 
CGCCAGGGCA GCCGGGAGTC CACCGATGGG AGCACCAACA GCAACAGCTC CGACGGCACG 
TTCATCTTCC CCACTACCCG GCTAGGGGCT GAAAGCCAGT TCAGCGATTT CCTGGATGGG 
CTGGGACCAG CTCAGATTGT GGGGCGACAG ACACTGGCAA CACCACCCAT GGGAGATGTG 
CACATTGCCA TCATGGACCG GAGTGGCCAG CTGGAGGTGG AAGTGATTGA AGCTCGGGGC 
CTGACCCCCA AACCAGGCTC CAAATCCCTC CCAGCCACCT ATATCAAGGT TTACCTGCTG 
GAGAATGGGG CCTGCTTGGC CAAGAAGAAG ACAAAGATGA CCAAGAAGAC CTGTGATCCC 
CTGTACCAGC AGGCTCTGCT CTTTGACGAG GGACCCCAGG GCAAGGTGCT GCAGGTGATC 
GTCTGGGGAG ACTATGGCCG CATGGACCAC AAGTGCTTCA TGGGCATGGC CCAGATCATG 
CTGGACGAGC TGGACCTCAG CGCCGCGGTC ACCGGCTGGT ACAAACTCTT CCCCACCTCC 
TCAGTGGCAG ACTCCACACT CGGATCCCTC ACCAGGCGCC TGTCCCAGTC TTCCCTGGAG 
AGTGCCACCA GCCCCTCATG CTCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055562.2
CDS	496..1422
Translation	MFNGEPGPASSGASRNVVRSSSISGEICGSQQAGGGAGTTTAKKRRSSLGAKMVAIVGLTQWSKSTLQLPQPEGATKKLRSNIRRSTETGIAVEMRSRVTRQGSRESTDGSTNSNSSDGTFIFPTTRLGAESQFSDFLDGLGPAQIVGRQTLATPPMGDVHIAIMDRSGQLEVEVIEARGLTPKPGSKSLPATYIKVYLLENGACLAKKKTKMTKKTCDPLYQQALLFDEGPQGKVLQVIVWGDYGRMDHKCFMGMAQIMLDELDLSAAVTGWYKLFPTSSVADSTLGSLTRRLSQSSLESATSPSCS

Target ORF information:

RefSeq Version	NM_014747.3
Organism	Homo sapiens(human)
Definition	Homo sapiens regulating synaptic membrane exocytosis 3 (RIMS3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014747.3

ORF Insert Sequence:

ATGTTTAACG GGGAGCCAGG TCCTGCCTCA TCTGGGGCCT CCAGGAATGT GGTGCGGAGC 
TCCAGCATTA GCGGTGAAAT CTGCGGATCC CAGCAAGCCG GGGGCGGGGC TGGGACCACC 
ACCGCCAAGA AGCGGCGGAG CAGCCTGGGT GCCAAGATGG TGGCCATCGT GGGCCTGACT 
CAGTGGAGCA AGAGCACACT CCAGCTTCCG CAGCCTGAAG GGGCCACCAA GAAGCTGCGC 
AGCAACATCC GCCGGAGCAC GGAGACAGGC ATCGCGGTGG AGATGCGGAG CCGGGTCACA 
CGCCAGGGCA GCCGGGAGTC CACCGATGGG AGCACCAACA GCAACAGCTC CGACGGCACG 
TTCATCTTCC CCACTACCCG GCTAGGGGCT GAAAGCCAGT TCAGCGATTT CCTGGATGGG 
CTGGGACCAG CTCAGATTGT GGGGCGACAG ACACTGGCAA CACCACCCAT GGGAGATGTG 
CACATTGCCA TCATGGACCG GAGTGGCCAG CTGGAGGTGG AAGTGATTGA AGCTCGGGGC 
CTGACCCCCA AACCAGGCTC CAAATCCCTC CCAGCCACCT ATATCAAGGT TTACCTGCTG 
GAGAATGGGG CCTGCTTGGC CAAGAAGAAG ACAAAGATGA CCAAGAAGAC CTGTGATCCC 
CTGTACCAGC AGGCTCTGCT CTTTGACGAG GGACCCCAGG GCAAGGTGCT GCAGGTGATC 
GTCTGGGGAG ACTATGGCCG CATGGACCAC AAGTGCTTCA TGGGCATGGC CCAGATCATG 
CTGGACGAGC TGGACCTCAG CGCCGCGGTC ACCGGCTGGT ACAAACTCTT CCCCACCTCC 
TCAGTGGCAG ACTCCACACT CGGATCCCTC ACCAGGCGCC TGTCCCAGTC TTCCCTGGAG 
AGTGCCACCA GCCCCTCATG CTCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RIMS3 ( XM_011542480.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011540782.1 Homo sapiens regulating synaptic membrane exocytosis 3 (RIMS3), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu18397
Clone ID Related Accession (Same CDS sequence)	NM_014747.2 , XM_011542480.1 , NM_014747.3
Accession Version	XM_011542480.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 927bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-11
Organism	Homo sapiens(Human)
Product	regulating synaptic membrane exocytosis protein 3 isoform X1
Comment

ATGTTTAACG GGGAGCCAGG TCCTGCCTCA TCTGGGGCCT CCAGGAATGT GGTGCGGAGC 
TCCAGCATTA GCGGTGAAAT CTGCGGATCC CAGCAAGCCG GGGGCGGGGC TGGGACCACC 
ACCGCCAAGA AGCGGCGGAG CAGCCTGGGT GCCAAGATGG TGGCCATCGT GGGCCTGACT 
CAGTGGAGCA AGAGCACACT CCAGCTTCCG CAGCCTGAAG GGGCCACCAA GAAGCTGCGC 
AGCAACATCC GCCGGAGCAC GGAGACAGGC ATCGCGGTGG AGATGCGGAG CCGGGTCACA 
CGCCAGGGCA GCCGGGAGTC CACCGATGGG AGCACCAACA GCAACAGCTC CGACGGCACG 
TTCATCTTCC CCACTACCCG GCTAGGGGCT GAAAGCCAGT TCAGCGATTT CCTGGATGGG 
CTGGGACCAG CTCAGATTGT GGGGCGACAG ACACTGGCAA CACCACCCAT GGGAGATGTG 
CACATTGCCA TCATGGACCG GAGTGGCCAG CTGGAGGTGG AAGTGATTGA AGCTCGGGGC 
CTGACCCCCA AACCAGGCTC CAAATCCCTC CCAGCCACCT ATATCAAGGT TTACCTGCTG 
GAGAATGGGG CCTGCTTGGC CAAGAAGAAG ACAAAGATGA CCAAGAAGAC CTGTGATCCC 
CTGTACCAGC AGGCTCTGCT CTTTGACGAG GGACCCCAGG GCAAGGTGCT GCAGGTGATC 
GTCTGGGGAG ACTATGGCCG CATGGACCAC AAGTGCTTCA TGGGCATGGC CCAGATCATG 
CTGGACGAGC TGGACCTCAG CGCCGCGGTC ACCGGCTGGT ACAAACTCTT CCCCACCTCC 
TCAGTGGCAG ACTCCACACT CGGATCCCTC ACCAGGCGCC TGTCCCAGTC TTCCCTGGAG 
AGTGCCACCA GCCCCTCATG CTCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011540782.1
Translation	MFNGEPGPASSGASRNVVRSSSISGEICGSQQAGGGAGTTTAKKRRSSLGAKMVAIVGLTQWSKSTLQLPQPEGATKKLRSNIRRSTETGIAVEMRSRVTRQGSRESTDGSTNSNSSDGTFIFPTTRLGAESQFSDFLDGLGPAQIVGRQTLATPPMGDVHIAIMDRSGQLEVEVIEARGLTPKPGSKSLPATYIKVYLLENGACLAKKKTKMTKKTCDPLYQQALLFDEGPQGKVLQVIVWGDYGRMDHKCFMGMAQIMLDELDLSAAVTGWYKLFPTSSVADSTLGSLTRRLSQSSLESATSPSCS

Target ORF information:

RefSeq Version	XM_011542480.1
Organism	Homo sapiens(Human)
Definition	Homo sapiens regulating synaptic membrane exocytosis 3 (RIMS3), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011542480.1

ORF Insert Sequence:

ATGTTTAACG GGGAGCCAGG TCCTGCCTCA TCTGGGGCCT CCAGGAATGT GGTGCGGAGC 
TCCAGCATTA GCGGTGAAAT CTGCGGATCC CAGCAAGCCG GGGGCGGGGC TGGGACCACC 
ACCGCCAAGA AGCGGCGGAG CAGCCTGGGT GCCAAGATGG TGGCCATCGT GGGCCTGACT 
CAGTGGAGCA AGAGCACACT CCAGCTTCCG CAGCCTGAAG GGGCCACCAA GAAGCTGCGC 
AGCAACATCC GCCGGAGCAC GGAGACAGGC ATCGCGGTGG AGATGCGGAG CCGGGTCACA 
CGCCAGGGCA GCCGGGAGTC CACCGATGGG AGCACCAACA GCAACAGCTC CGACGGCACG 
TTCATCTTCC CCACTACCCG GCTAGGGGCT GAAAGCCAGT TCAGCGATTT CCTGGATGGG 
CTGGGACCAG CTCAGATTGT GGGGCGACAG ACACTGGCAA CACCACCCAT GGGAGATGTG 
CACATTGCCA TCATGGACCG GAGTGGCCAG CTGGAGGTGG AAGTGATTGA AGCTCGGGGC 
CTGACCCCCA AACCAGGCTC CAAATCCCTC CCAGCCACCT ATATCAAGGT TTACCTGCTG 
GAGAATGGGG CCTGCTTGGC CAAGAAGAAG ACAAAGATGA CCAAGAAGAC CTGTGATCCC 
CTGTACCAGC AGGCTCTGCT CTTTGACGAG GGACCCCAGG GCAAGGTGCT GCAGGTGATC 
GTCTGGGGAG ACTATGGCCG CATGGACCAC AAGTGCTTCA TGGGCATGGC CCAGATCATG 
CTGGACGAGC TGGACCTCAG CGCCGCGGTC ACCGGCTGGT ACAAACTCTT CCCCACCTCC 
TCAGTGGCAG ACTCCACACT CGGATCCCTC ACCAGGCGCC TGTCCCAGTC TTCCCTGGAG 
AGTGCCACCA GCCCCTCATG CTCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RIMS3 ( XM_011542479.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011540781.1 Homo sapiens regulating synaptic membrane exocytosis 3 (RIMS3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu63294
Clone ID Related Accession (Same CDS sequence)	XM_011542479.2
Accession Version	XM_011542479.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 939bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	regulating synaptic membrane exocytosis protein 3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011542479.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGGCGG GCAGGACGGA CCGAGCTACA GCAGCGGCCG CGCGAGGAAG TGAGACCCTT 
TTATCACATC GCCTCCTCTG GGAGCCTGCC CTGATTGCCT TCACCTCATT TCTTGAAAAT 
TGGTGTTTTG GCAGAAGTCA ATTGAAGCCT TGTGCAAATG CCCTAGGGGT GTGCTGTTGG 
GAGGCAGCCC CCTGTGATGC GGAACACCAG GCTCAGATTC ATCAGTTCGA AGGGGCCACC 
AAGAAGCTGC GCAGCAACAT CCGCCGGAGC ACGGAGACAG GCATCGCGGT GGAGATGCGG 
AGCCGGGTCA CACGCCAGGG CAGCCGGGAG TCCACCGATG GGAGCACCAA CAGCAACAGC 
TCCGACGGCA CGTTCATCTT CCCCACTACC CGGCTAGGGG CTGAAAGCCA GTTCAGCGAT 
TTCCTGGATG GGCTGGGACC AGCTCAGATT GTGGGGCGAC AGACACTGGC AACACCACCC 
ATGGGAGATG TGCACATTGC CATCATGGAC CGGAGTGGCC AGCTGGAGGT GGAAGTGATT 
GAAGCTCGGG GCCTGACCCC CAAACCAGGC TCCAAATCCC TCCCAGCCAC CTATATCAAG 
GTTTACCTGC TGGAGAATGG GGCCTGCTTG GCCAAGAAGA AGACAAAGAT GACCAAGAAG 
ACCTGTGATC CCCTGTACCA GCAGGCTCTG CTCTTTGACG AGGGACCCCA GGGCAAGGTG 
CTGCAGGTGA TCGTCTGGGG AGACTATGGC CGCATGGACC ACAAGTGCTT CATGGGCATG 
GCCCAGATCA TGCTGGACGA GCTGGACCTC AGCGCCGCGG TCACCGGCTG GTACAAACTC 
TTCCCCACCT CCTCAGTGGC AGACTCCACA CTCGGATCCC TCACCAGGCG CCTGTCCCAG 
TCTTCCCTGG AGAGTGCCAC CAGCCCCTCA TGCTCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011540781.1
CDS	96..1034
Translation	MAAGRTDRATAAAARGSETLLSHRLLWEPALIAFTSFLENWCFGRSQLKPCANALGVCCWEAAPCDAEHQAQIHQFEGATKKLRSNIRRSTETGIAVEMRSRVTRQGSRESTDGSTNSNSSDGTFIFPTTRLGAESQFSDFLDGLGPAQIVGRQTLATPPMGDVHIAIMDRSGQLEVEVIEARGLTPKPGSKSLPATYIKVYLLENGACLAKKKTKMTKKTCDPLYQQALLFDEGPQGKVLQVIVWGDYGRMDHKCFMGMAQIMLDELDLSAAVTGWYKLFPTSSVADSTLGSLTRRLSQSSLESATSPSCS

Target ORF information:

RefSeq Version	XM_011542479.2
Organism	Homo sapiens(human)
Definition	Homo sapiens regulating synaptic membrane exocytosis 3 (RIMS3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011542479.2

ORF Insert Sequence:

ATGGCGGCGG GCAGGACGGA CCGAGCTACA GCAGCGGCCG CGCGAGGAAG TGAGACCCTT 
TTATCACATC GCCTCCTCTG GGAGCCTGCC CTGATTGCCT TCACCTCATT TCTTGAAAAT 
TGGTGTTTTG GCAGAAGTCA ATTGAAGCCT TGTGCAAATG CCCTAGGGGT GTGCTGTTGG 
GAGGCAGCCC CCTGTGATGC GGAACACCAG GCTCAGATTC ATCAGTTCGA AGGGGCCACC 
AAGAAGCTGC GCAGCAACAT CCGCCGGAGC ACGGAGACAG GCATCGCGGT GGAGATGCGG 
AGCCGGGTCA CACGCCAGGG CAGCCGGGAG TCCACCGATG GGAGCACCAA CAGCAACAGC 
TCCGACGGCA CGTTCATCTT CCCCACTACC CGGCTAGGGG CTGAAAGCCA GTTCAGCGAT 
TTCCTGGATG GGCTGGGACC AGCTCAGATT GTGGGGCGAC AGACACTGGC AACACCACCC 
ATGGGAGATG TGCACATTGC CATCATGGAC CGGAGTGGCC AGCTGGAGGT GGAAGTGATT 
GAAGCTCGGG GCCTGACCCC CAAACCAGGC TCCAAATCCC TCCCAGCCAC CTATATCAAG 
GTTTACCTGC TGGAGAATGG GGCCTGCTTG GCCAAGAAGA AGACAAAGAT GACCAAGAAG 
ACCTGTGATC CCCTGTACCA GCAGGCTCTG CTCTTTGACG AGGGACCCCA GGGCAAGGTG 
CTGCAGGTGA TCGTCTGGGG AGACTATGGC CGCATGGACC ACAAGTGCTT CATGGGCATG 
GCCCAGATCA TGCTGGACGA GCTGGACCTC AGCGCCGCGG TCACCGGCTG GTACAAACTC 
TTCCCCACCT CCTCAGTGGC AGACTCCACA CTCGGATCCC TCACCAGGCG CCTGTCCCAG 
TCTTCCCTGG AGAGTGCCAC CAGCCCCTCA TGCTCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Genome-Wide Detection of Copy Number Variations in Unsolved Inherited Retinal Disease.
Investigative ophthalmology & visual science58(1)424-429(2017 01)
Huang XF,Mao JY,Huang ZQ,Rao FQ,Cheng FF,Li FF,Wang QF,Jin ZB

Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism.
Nature communications53650(2014 Apr)
Corominas R,Yang X,Lin GN,Kang S,Shen Y,Ghamsari L,Broly M,Rodriguez M,Tam S,Trigg SA,Fan C,Yi S,Tasan M,Lemmens I,Kuang X,Zhao N,Malhotra D,Michaelson JJ,Vacic V,Calderwood MA,Roth FP,Tavernier J,Horvath S,Salehi-Ashtiani K,Korkin D,Sebat J,Hill DE,Hao T,Vidal M,Iakoucheva LM

Image-based genome-wide siRNA screen identifies selective autophagy factors.
Nature480(7375)113-7(2011 Dec)
Orvedahl A,Sumpter R Jr,Xiao G,Ng A,Zou Z,Tang Y,Narimatsu M,Gilpin C,Sun Q,Roth M,Forst CV,Wrana JL,Zhang YE,Luby-Phelps K,Xavier RJ,Xie Y,Levine B

A de novo 1p34.2 microdeletion identifies the synaptic vesicle gene RIMS3 as a novel candidate for autism.
Journal of medical genetics47(2)81-90(2010 Feb)
Kumar RA,Sudi J,Babatz TD,Brune CW,Oswald D,Yen M,Nowak NJ,Cook EH,Christian SL,Dobyns WB

Investigation of the expression of genes affecting cytomatrix active zone function in the amygdala in schizophrenia: effects of antipsychotic drugs.
Journal of psychiatric research43(3)282-90(2009 Jan)
Weidenhofer J,Scott RJ,Tooney PA

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RIMS3 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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