Gene Symbol | PRPF4 |
Entrez Gene ID | 9128 |
Full Name | pre-mRNA processing factor 4 |
Synonyms | HPRP4,HPRP4P,PRP4,Prp4p,RP70,SNRNP60 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | The protein encoded by this gene is part of a heteromeric complex that binds U4, U5, and U6 small nuclear RNAs and is involved in pre-mRNA splicing. The encoded protein also is a mitotic checkpoint protein and a regulator of chemoresistance in human ovarian cancer. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2016]. |
Disorder MIM: | |
Disorder Html: | Retinitis pigmentosa 70, 615922 (3) |