RTL8C cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	RTL8C
Entrez Gene ID	8933
Full Name	retrotransposon Gag like 8C
Synonyms	CXX1,FAM127A,MAR8C,MART8C,Mar8,Mart8,SIRH5
General protein information	Preferred Names retrotransposon Gag like 8C Names retrotransposon Gag-like protein 8B CAAX box 1 Sushi-Ichi retrotransposon homolog 5 family with sequence similarity 127 member A mammalian retrotransposon derived protein 8C mammalian retrotransposon-derived 8C protein FAM127A
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: X Map Location: Xq26.3
Disorder MIM:	300213

mRNA and Protein(s)

mRNA	Protein	Name
NM_001078171.2	NP_001071639.1	retrotransposon Gag-like protein 8C
NM_001078171.1	NP_001071639.1	retrotransposon Gag-like protein 8B

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	FAM127A	XP_001135503.2
	FAM127A	XP_001099466.1
Canis lupus familiaris (dog)	LOC102152178	XP_005641906.1
Bos taurus (cattle)	LOC783730	XP_002699607.1
Canis lupus familiaris (dog)	LOC100683463	XP_005641904.1
Canis lupus familiaris (dog)	LOC100683691	XP_005641907.1
Canis lupus familiaris (dog)	LOC100683545	XP_005641905.1
Mus musculus (house mouse)	Cxx1c	NP_082651.1
Homo sapiens (human)	FAM127A	NP_001071639.1
Bos taurus (cattle)	FAM127C	NP_001068990.1
Bos taurus (cattle)	LOC615809	NP_001192205.1

Gene Ontology
Bibliography

Related articles in PubMed

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.
Lim J, Hao T, Shaw C, Patel AJ, Szab? G, Rual JF, Fisk CJ, Li N, Smolyar A, Hill DE, Barab?si AL, Vidal M, Zoghbi HY
Cell125(4)801-14(2006 May)

The DNA sequence of the human X chromosome.
Ross MT, Grafham DV, Coffey AJ, Scherer S, McLay K, Muzny D, Platzer M, Howell GR, Burrows C, Bird CP, Frankish A, Lovell FL, Howe KL, Ashurst JL, Fulton RS, Sudbrak R, Wen G, Jones MC, Hurles ME, Andrews TD, Scott CE, Searle S, Ramser J, Whittaker A, Deadman R, Carter NP, Hunt SE, Chen R, Cree A, Gunaratne P, Havlak P, Hodgson A, Metzker ML, Richards S, Scott G, Steffen D, Sodergren E, Wheeler DA, Worley KC, Ainscough R, Ambrose KD, Ansari-Lari MA, Aradhya S, Ashwell RI, Babbage AK, Bagguley CL, Ballabio A, Banerjee R, Barker GE, Barlow KF, Barrett IP, Bates KN, Beare DM, Beasley H, Beasley O, Beck A, Bethel G, Blechschmidt K, Brady N, Bray-Allen S, Bridgeman AM, Brown AJ, Brown MJ, Bonnin D, Bruford EA, Buhay C, Burch P, Burford D, Burgess J, Burrill W, Burton J, Bye JM, Carder C, Carrel L, Chako J, Chapman JC, Chavez D, Chen E, Chen G, Chen Y, Chen Z, Chinault C, Ciccodicola A, Clark SY, Clarke G, Clee CM, Clegg S, Clerc-Blankenburg K, Clifford K, Cobley V, Cole CG, Conquer JS, Corby N, Connor RE, David R, Davies J, Davis C, Davis J, Delgado O, Deshazo D, Dhami P, Ding Y, Dinh H, Dodsworth S, Draper H, Dugan-Rocha S, Dunham A, Dunn M, Durbin KJ, Dutta I, Eades T, Ellwood M, Emery-Cohen A, Errington H, Evans KL, Faulkner L, Francis F, Frankland J, Fraser AE, Galgoczy P, Gilbert J, Gill R, Gl?ckner G, Gregory SG, Gribble S, Griffiths C, Grocock R, Gu Y, Gwilliam R, Hamilton C, Hart EA, Hawes A, Heath PD, Heitmann K, Hennig S, Hernandez J, Hinzmann B, Ho S, Hoffs M, Howden PJ, Huckle EJ, Hume J, Hunt PJ, Hunt AR, Isherwood J, Jacob L, Johnson D, Jones S, de Jong PJ, Joseph SS, Keenan S, Kelly S, Kershaw JK, Khan Z, Kioschis P, Klages S, Knights AJ, Kosiura A, Kovar-Smith C, Laird GK, Langford C, Lawlor S, Leversha M, Lewis L, Liu W, Lloyd C, Lloyd DM, Loulseged H, Loveland JE, Lovell JD, Lozado R, Lu J, Lyne R, Ma J, Maheshwari M, Matthews LH, McDowall J, McLaren S, McMurray A, Meidl P, Meitinger T, Milne S, Miner G, Mistry SL, Morgan M, Morris S, M?ller I, Mullikin JC, Nguyen N, Nordsiek G, Nyakatura G, O'Dell CN, Okwuonu G, Palmer S, Pandian R, Parker D, Parrish J, Pasternak S, Patel D, Pearce AV, Pearson DM, Pelan SE, Perez L, Porter KM, Ramsey Y, Reichwald K, Rhodes S, Ridler KA, Schlessinger D, Schueler MG, Sehra HK, Shaw-Smith C, Shen H, Sheridan EM, Shownkeen R, Skuce CD, Smith ML, Sotheran EC, Steingruber HE, Steward CA, Storey R, Swann RM, Swarbreck D, Tabor PE, Taudien S, Taylor T, Teague B, Thomas K, Thorpe A, Timms K, Tracey A, Trevanion S, Tromans AC, d'Urso M, Verduzco D, Villasana D, Waldron L, Wall M, Wang Q, Warren J, Warry GL, Wei X, West A, Whitehead SL, Whiteley MN, Wilkinson JE, Willey DL, Williams G, Williams L, Williamson A, Williamson H, Wilming L, Woodmansey RL, Wray PW, Yen J, Zhang J, Zhou J, Zoghbi H, Zorilla S, Buck D, Reinhardt R, Poustka A, Rosenthal A, Lehrach H, Meindl A, Minx PJ, Hillier LW, Willard HF, Wilson RK, Waterston RH, Rice CM, Vaudin M, Coulson A, Nelson DL, Weinstock G, Sulston JE, Durbin R, Hubbard T, Gibbs RA, Beck S, Rogers J, Bentley DR
Nature434(7031)325-37(2005 Mar)

A family of neofunctionalized Ty3/gypsy retrotransposon genes in mammalian genomes.
Brandt J, Veith AM, Volff JN
Cytogenetic and genome research110(1-4)307-17(2005)

Transposable elements as a source of genetic innovation: expression and evolution of a family of retrotransposon-derived neogenes in mammals.
Brandt J, Schrauth S, Veith AM, Froschauer A, Haneke T, Schultheis C, Gessler M, Leimeister C, Volff JN
Gene345(1)101-11(2005 Jan)

A low-copy repeat in Xq26 represents a novel putatively prenylated protein gene (CXX1) and its pseudogenes (DXS9914, DXS9915, and DXS9916).
Frattini A, Faranda S, Zucchi I, Vezzoni P
Genomics46(1)167-9(1997 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following RTL8C gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RTL8C cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu29991	NM_001078171.2 Latest version!	Homo sapiens retrotransposon Gag like 8C (RTL8C), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu29991	NM_001078171.1	Homo sapiens retrotransposon Gag like 8C (RTL8C), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

RTL8C ( NM_001078171.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001071639.1 Homo sapiens retrotransposon Gag like 8C (RTL8C), mRNA.

Price & Availability↑

CloneID	OHu29991
Clone ID Related Accession (Same CDS sequence)	NM_001078171.2 , NM_001078171.1
Accession Version	NM_001078171.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 342bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-24
Organism	Homo sapiens(human)
Product	retrotransposon Gag-like protein 8C
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CX784259.1, BC002385.2 and CD367165.1. On May 17, 2019 this sequence version replaced NM_001078171.1. ##Evidence-Data-START## Transcript is intronless :: SRR5189652.194787.1, SRR5189655.66695.1 [ECO:0000345] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000257013.9/ ENSP00000257013.7 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGACGGTC GGGTGCAGCT GATAAAGGCC CTCCTGGCCT TGCCGATCCG GCCTGCGACG 
CGTCGCTGGA GGAACCCGAT TCCCTTTCCC GAGACGTTTG ACGGCGATAC CGACCGACTC 
CCGGAGTTCA TCGTGCAGAC GGGCTCCTAC ATGTTCGTGG ACGAGAACAC GTTCTCCAGC 
GACGCCCTGA AGGTGACGTT CCTCATCACC CGCCTCACAG GGCCCGCCCT GCAGTGGGTG 
ATCCCCTACA TCAAGAAGGA GAGCCCCCTC CTCAATGATT ACCGGGGCTT TCTGGCCGAG 
ATGAAGCGAG TCTTTGGATG GGAGGAGGAC GAGGACTTCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001071639.1
CDS	30..371
Translation	MDGRVQLIKALLALPIRPATRRWRNPIPFPETFDGDTDRLPEFIVQTGSYMFVDENTFSSDALKVTFLITRLTGPALQWVIPYIKKESPLLNDYRGFLAEMKRVFGWEEDEDF

Target ORF information:

RefSeq Version	NM_001078171.2
Organism	Homo sapiens(human)
Definition	Homo sapiens retrotransposon Gag like 8C (RTL8C), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001078171.2

ORF Insert Sequence:

ATGGACGGTC GGGTGCAGCT GATAAAGGCC CTCCTGGCCT TGCCGATCCG GCCTGCGACG 
CGTCGCTGGA GGAACCCGAT TCCCTTTCCC GAGACGTTTG ACGGCGATAC CGACCGACTC 
CCGGAGTTCA TCGTGCAGAC GGGCTCCTAC ATGTTCGTGG ACGAGAACAC GTTCTCCAGC 
GACGCCCTGA AGGTGACGTT CCTCATCACC CGCCTCACAG GGCCCGCCCT GCAGTGGGTG 
ATCCCCTACA TCAAGAAGGA GAGCCCCCTC CTCAATGATT ACCGGGGCTT TCTGGCCGAG 
ATGAAGCGAG TCTTTGGATG GGAGGAGGAC GAGGACTTCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RTL8C ( NM_001078171.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001071639.1 Homo sapiens retrotransposon Gag like 8C (RTL8C), mRNA.

Price & Availability↑

CloneID	OHu29991
Clone ID Related Accession (Same CDS sequence)	NM_001078171.2 , NM_001078171.1
Accession Version	NM_001078171.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 342bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-22
Organism	Homo sapiens(human)
Product	retrotransposon Gag-like protein 8B
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CX784259.1, BC002385.2 and CD367165.1. COMPLETENESS: complete on the 3' end.

ATGGACGGTC GGGTGCAGCT GATAAAGGCC CTCCTGGCCT TGCCGATCCG GCCTGCGACG 
CGTCGCTGGA GGAACCCGAT TCCCTTTCCC GAGACGTTTG ACGGCGATAC CGACCGACTC 
CCGGAGTTCA TCGTGCAGAC GGGCTCCTAC ATGTTCGTGG ACGAGAACAC GTTCTCCAGC 
GACGCCCTGA AGGTGACGTT CCTCATCACC CGCCTCACAG GGCCCGCCCT GCAGTGGGTG 
ATCCCCTACA TCAAGAAGGA GAGCCCCCTC CTCAATGATT ACCGGGGCTT TCTGGCCGAG 
ATGAAGCGAG TCTTTGGATG GGAGGAGGAC GAGGACTTCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001071639.1
CDS	82..423
Translation	MDGRVQLIKALLALPIRPATRRWRNPIPFPETFDGDTDRLPEFIVQTGSYMFVDENTFSSDALKVTFLITRLTGPALQWVIPYIKKESPLLNDYRGFLAEMKRVFGWEEDEDF

Target ORF information:

RefSeq Version	NM_001078171.1
Organism	Homo sapiens(human)
Definition	Homo sapiens retrotransposon Gag like 8C (RTL8C), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001078171.1

ORF Insert Sequence:

ATGGACGGTC GGGTGCAGCT GATAAAGGCC CTCCTGGCCT TGCCGATCCG GCCTGCGACG 
CGTCGCTGGA GGAACCCGAT TCCCTTTCCC GAGACGTTTG ACGGCGATAC CGACCGACTC 
CCGGAGTTCA TCGTGCAGAC GGGCTCCTAC ATGTTCGTGG ACGAGAACAC GTTCTCCAGC 
GACGCCCTGA AGGTGACGTT CCTCATCACC CGCCTCACAG GGCCCGCCCT GCAGTGGGTG 
ATCCCCTACA TCAAGAAGGA GAGCCCCCTC CTCAATGATT ACCGGGGCTT TCTGGCCGAG 
ATGAAGCGAG TCTTTGGATG GGAGGAGGAC GAGGACTTCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.
Cell125(4)801-14(2006 May)
Lim J,Hao T,Shaw C,Patel AJ,Szab? G,Rual JF,Fisk CJ,Li N,Smolyar A,Hill DE,Barab?si AL,Vidal M,Zoghbi HY

The DNA sequence of the human X chromosome.
Nature434(7031)325-37(2005 Mar)
Ross MT,Grafham DV,Coffey AJ,Scherer S,McLay K,Muzny D,Platzer M,Howell GR,Burrows C,Bird CP,Frankish A,Lovell FL,Howe KL,Ashurst JL,Fulton RS,Sudbrak R,Wen G,Jones MC,Hurles ME,Andrews TD,Scott CE,Searle S,Ramser J,Whittaker A,Deadman R,Carter NP,Hunt SE,Chen R,Cree A,Gunaratne P,Havlak P,Hodgson A,Metzker ML,Richards S,Scott G,Steffen D,Sodergren E,Wheeler DA,Worley KC,Ainscough R,Ambrose KD,Ansari-Lari MA,Aradhya S,Ashwell RI,Babbage AK,Bagguley CL,Ballabio A,Banerjee R,Barker GE,Barlow KF,Barrett IP,Bates KN,Beare DM,Beasley H,Beasley O,Beck A,Bethel G,Blechschmidt K,Brady N,Bray-Allen S,Bridgeman AM,Brown AJ,Brown MJ,Bonnin D,Bruford EA,Buhay C,Burch P,Burford D,Burgess J,Burrill W,Burton J,Bye JM,Carder C,Carrel L,Chako J,Chapman JC,Chavez D,Chen E,Chen G,Chen Y,Chen Z,Chinault C,Ciccodicola A,Clark SY,Clarke G,Clee CM,Clegg S,Clerc-Blankenburg K,Clifford K,Cobley V,Cole CG,Conquer JS,Corby N,Connor RE,David R,Davies J,Davis C,Davis J,Delgado O,Deshazo D,Dhami P,Ding Y,Dinh H,Dodsworth S,Draper H,Dugan-Rocha S,Dunham A,Dunn M,Durbin KJ,Dutta I,Eades T,Ellwood M,Emery-Cohen A,Errington H,Evans KL,Faulkner L,Francis F,Frankland J,Fraser AE,Galgoczy P,Gilbert J,Gill R,Gl?ckner G,Gregory SG,Gribble S,Griffiths C,Grocock R,Gu Y,Gwilliam R,Hamilton C,Hart EA,Hawes A,Heath PD,Heitmann K,Hennig S,Hernandez J,Hinzmann B,Ho S,Hoffs M,Howden PJ,Huckle EJ,Hume J,Hunt PJ,Hunt AR,Isherwood J,Jacob L,Johnson D,Jones S,de Jong PJ,Joseph SS,Keenan S,Kelly S,Kershaw JK,Khan Z,Kioschis P,Klages S,Knights AJ,Kosiura A,Kovar-Smith C,Laird GK,Langford C,Lawlor S,Leversha M,Lewis L,Liu W,Lloyd C,Lloyd DM,Loulseged H,Loveland JE,Lovell JD,Lozado R,Lu J,Lyne R,Ma J,Maheshwari M,Matthews LH,McDowall J,McLaren S,McMurray A,Meidl P,Meitinger T,Milne S,Miner G,Mistry SL,Morgan M,Morris S,M?ller I,Mullikin JC,Nguyen N,Nordsiek G,Nyakatura G,O'Dell CN,Okwuonu G,Palmer S,Pandian R,Parker D,Parrish J,Pasternak S,Patel D,Pearce AV,Pearson DM,Pelan SE,Perez L,Porter KM,Ramsey Y,Reichwald K,Rhodes S,Ridler KA,Schlessinger D,Schueler MG,Sehra HK,Shaw-Smith C,Shen H,Sheridan EM,Shownkeen R,Skuce CD,Smith ML,Sotheran EC,Steingruber HE,Steward CA,Storey R,Swann RM,Swarbreck D,Tabor PE,Taudien S,Taylor T,Teague B,Thomas K,Thorpe A,Timms K,Tracey A,Trevanion S,Tromans AC,d'Urso M,Verduzco D,Villasana D,Waldron L,Wall M,Wang Q,Warren J,Warry GL,Wei X,West A,Whitehead SL,Whiteley MN,Wilkinson JE,Willey DL,Williams G,Williams L,Williamson A,Williamson H,Wilming L,Woodmansey RL,Wray PW,Yen J,Zhang J,Zhou J,Zoghbi H,Zorilla S,Buck D,Reinhardt R,Poustka A,Rosenthal A,Lehrach H,Meindl A,Minx PJ,Hillier LW,Willard HF,Wilson RK,Waterston RH,Rice CM,Vaudin M,Coulson A,Nelson DL,Weinstock G,Sulston JE,Durbin R,Hubbard T,Gibbs RA,Beck S,Rogers J,Bentley DR

A family of neofunctionalized Ty3/gypsy retrotransposon genes in mammalian genomes.
Cytogenetic and genome research110(1-4)307-17(2005)
Brandt J,Veith AM,Volff JN

Transposable elements as a source of genetic innovation: expression and evolution of a family of retrotransposon-derived neogenes in mammals.
Gene345(1)101-11(2005 Jan)
Brandt J,Schrauth S,Veith AM,Froschauer A,Haneke T,Schultheis C,Gessler M,Leimeister C,Volff JN

A low-copy repeat in Xq26 represents a novel putatively prenylated protein gene (CXX1) and its pseudogenes (DXS9914, DXS9915, and DXS9916).
Genomics46(1)167-9(1997 Nov)
Frattini A,Faranda S,Zucchi I,Vezzoni P