Gene Symbol | DEGS1 |
Entrez Gene ID | 8560 |
Full Name | delta 4-desaturase, sphingolipid 1 |
Synonyms | DEGS,DEGS-1,DES1,Des-1,FADS7,MIG15,MLD |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes a member of the membrane fatty acid desaturase family which is responsible for inserting double bonds into specific positions in fatty acids. This protein contains three His-containing consensus motifs that are characteristic of a group of membrane fatty acid desaturases. It is predicted to be a multiple membrane-spanning protein localized to the endoplasmic reticulum. Overexpression of this gene inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulating biosynthetic processing of the EGF receptor. [provided by RefSeq, Mar 2010]. |
Disorder MIM: |