PCGF1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	PCGF1
Entrez Gene ID	84759
Full Name	polycomb group ring finger 1
Synonyms	2010002K04Rik,NSPC1,RNF3A-2,RNF68
General protein information	Preferred Names polycomb group ring finger 1 Names polycomb group RING finger protein 1 RING finger protein 68 nervous system Polycomb-1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 2 Map Location: 2p13.1
Summary	PCGF1 is a mammalian homolog of the Drosophila polycomb group genes, which act as transcriptional repressors to regulate anterior-posterior patterning in early embryonic development (Nunes et al., 2001 [PubMed 11287196]). See also PCGF2 (MIM 600346).[supplied by OMIM, Aug 2008].
Disorder MIM:	610231

mRNA and Protein(s)

mRNA	Protein	Name
NM_032673.3	NP_116062.2	polycomb group RING finger protein 1
NM_032673.2	NP_116062.2	polycomb group RING finger protein 1
XM_024453181.1	XP_024308949.1	polycomb group RING finger protein 1 isoform X1

Pathways from BioSystems

Homologies

	LOC715341	XP_001105519.2
Pan troglodytes (chimpanzee)	PCGF1	XP_515562.2
Canis lupus familiaris (dog)	PCGF1	XP_532995.2
Bos taurus (cattle)	PCGF1	NP_001039912.2
Homo sapiens (human)	PCGF1	NP_116062.2
Rattus norvegicus (Norway rat)	Pcgf1	NP_001007001.1
Danio rerio (zebrafish)	pcgf1	NP_001007159.1
Mus musculus (house mouse)	Pcgf1	NP_932109.1
Gallus gallus (chicken)	PCGF1	XP_003643507.2

Gene Ontology
Bibliography

Related articles in PubMed

MicroRNA?320a inhibition decreases insulin?induced KGN cell proliferation and apoptosis by targeting PCGF1.
Yang L, Li Y, Wang X, Liu Y, Yang L
Molecular medicine reports16(4)5706-5712(2017 Oct)

NSPc1 promotes cancer stem cell self-renewal by repressing the synthesis of all-trans retinoic acid via targeting RDH16 in malignant glioma.
Hu PS, Xia QS, Wu F, Li DK, Qi YJ, Hu Y, Wei ZZ, Li SS, Tian NY, Wei QF, Shen LJ, Yin B, Jiang T, Yuan JG, Qiang BQ, Han W, Peng XZ
Oncogene36(33)4706-4718(2017 Aug)

Architecture of the human interactome defines protein communities and disease networks.
Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW
Nature545(7655)505-509(2017 05)

A High-Density Map for Navigating the Human Polycomb Complexome.
Hauri S, Comoglio F, Seimiya M, Gerstung M, Glatter T, Hansen K, Aebersold R, Paro R, Gstaiger M, Beisel C
Cell reports17(2)583-595(2016 10)

EZH2 and BCL6 Cooperate to Assemble CBX8-BCOR Complex to Repress Bivalent Promoters, Mediate Germinal Center Formation and Lymphomagenesis.
B?guelin W, Teater M, Gearhart MD, Calvo Fern?ndez MT, Goldstein RL, C?rdenas MG, Hatzi K, Rosen M, Shen H, Corcoran CM, Hamline MY, Gascoyne RD, Levine RL, Abdel-Wahab O, Licht JD, Shaknovich R, Elemento O, Bardwell VJ, Melnick AM
Cancer cell30(2)197-213(2016 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

these results demonstrate that NSPc1 promotes cancer stem cell self-renewal by repressing the synthesis of all-trans retinoic acid via targeting RDH16 and may provide novel targets for glioma treatment in the future.
Title: NSPc1 promotes cancer stem cell self-renewal by repressing the synthesis of all-trans retinoic acid via targeting RDH16 in malignant glioma.

knockdown of PCGF1 results in reduced expression of DPPA4 and other subunits of the variant PRC1 complex at both mRNA and protein levels. Thus, PCGF1 represents a physical and functional link between Polycomb function and pluripotency
Title: The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.

polycomb has a role in stem cell fate and development of cancer (review)
Title: Stem cells and cancer; the polycomb connection.

The following PCGF1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PCGF1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu05078	NM_032673.3 Latest version!	Homo sapiens polycomb group ring finger 1 (PCGF1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu35640	XM_024453181.1 Latest version!	Homo sapiens polycomb group ring finger 1 (PCGF1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
View Old Accession Versions >>
OHu05078	NM_032673.2	Homo sapiens polycomb group ring finger 1 (PCGF1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PCGF1 ( NM_032673.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_116062.2 Homo sapiens polycomb group ring finger 1 (PCGF1), mRNA.

Price & Availability↑

CloneID	OHu05078
Clone ID Related Accession (Same CDS sequence)	NM_032673.3 , NM_032673.2
Accession Version	NM_032673.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 780bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-25
Organism	Homo sapiens(human)
Product	polycomb group RING finger protein 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC005041.2, BU602498.1 and BC004952.1. On Nov 23, 2018 this sequence version replaced NM_032673.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR5189667.331340.1, SRR1163655.595382.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000233630.11/ ENSP00000233630.6 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCGTCTC CTCAGGGGGG CCAGATTGCG ATCGCGATGA GGCTTCGGAA CCAGCTCCAG 
TCAGTGTACA AGATGGACCC GCTACGGAAC GAGGAGGAGG TTCGAGTGAA GATCAAAGAC 
TTGAATGAAC ACATTGTTTG CTGCCTATGC GCCGGCTACT TCGTGGATGC CACCACCATC 
ACAGAGTGTC TTCATACTTT CTGCAAGAGT TGTATTGTGA AGTACCTCCA AACTAGCAAG 
TACTGCCCCA TGTGCAACAT TAAGATCCAC GAGACACAGC CACTGCTCAA CCTCAAACTG 
GACCGGGTCA TGCAGGACAT CGTGTATAAG CTGGTGCCTG GCTTGCAAGA CAGTGAAGAG 
AAACGGATTC GGGAATTCTA CCAGTCCCGA GGTTTGGACC GGGTCACCCA GCCCACTGGG 
GAAGAGCCAG CACTGAGCAA CCTCGGCCTC CCCTTCAGCA GCTTTGACCA CTCTAAAGCC 
CACTACTATC GCTATGATGA GCAGTTGAAC CTGTGCCTGG AGCGGCTGAG TTCTGGCAAA 
GACAAGAATA AAAGCGTCCT GCAGAACAAG TATGTCCGAT GTTCTGTTAG AGCTGAGGTA 
CGCCATCTCC GGAGGGTCCT GTGTCACCGC TTGATGCTAA ACCCTCAGCA TGTGCAGCTC 
CTTTTTGACA ATGAAGTTCT CCCTGATCAC ATGACAATGA AGCAGATATG GCTCTCCCGC 
TGGTTCGGCA AGCCATCCCC TTTGCTTTTA CAATACAGTG TGAAAGAGAA GAGGAGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_116062.2
CDS	28..807
Translation	MASPQGGQIAIAMRLRNQLQSVYKMDPLRNEEEVRVKIKDLNEHIVCCLCAGYFVDATTITECLHTFCKSCIVKYLQTSKYCPMCNIKIHETQPLLNLKLDRVMQDIVYKLVPGLQDSEEKRIREFYQSRGLDRVTQPTGEEPALSNLGLPFSSFDHSKAHYYRYDEQLNLCLERLSSGKDKNKSVLQNKYVRCSVRAEVRHLRRVLCHRLMLNPQHVQLLFDNEVLPDHMTMKQIWLSRWFGKPSPLLLQYSVKEKRR

Target ORF information:

RefSeq Version	NM_032673.3
Organism	Homo sapiens(human)
Definition	Homo sapiens polycomb group ring finger 1 (PCGF1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_032673.3

ORF Insert Sequence:

ATGGCGTCTC CTCAGGGGGG CCAGATTGCG ATCGCGATGA GGCTTCGGAA CCAGCTCCAG 
TCAGTGTACA AGATGGACCC GCTACGGAAC GAGGAGGAGG TTCGAGTGAA GATCAAAGAC 
TTGAATGAAC ACATTGTTTG CTGCCTATGC GCCGGCTACT TCGTGGATGC CACCACCATC 
ACAGAGTGTC TTCATACTTT CTGCAAGAGT TGTATTGTGA AGTACCTCCA AACTAGCAAG 
TACTGCCCCA TGTGCAACAT TAAGATCCAC GAGACACAGC CACTGCTCAA CCTCAAACTG 
GACCGGGTCA TGCAGGACAT CGTGTATAAG CTGGTGCCTG GCTTGCAAGA CAGTGAAGAG 
AAACGGATTC GGGAATTCTA CCAGTCCCGA GGTTTGGACC GGGTCACCCA GCCCACTGGG 
GAAGAGCCAG CACTGAGCAA CCTCGGCCTC CCCTTCAGCA GCTTTGACCA CTCTAAAGCC 
CACTACTATC GCTATGATGA GCAGTTGAAC CTGTGCCTGG AGCGGCTGAG TTCTGGCAAA 
GACAAGAATA AAAGCGTCCT GCAGAACAAG TATGTCCGAT GTTCTGTTAG AGCTGAGGTA 
CGCCATCTCC GGAGGGTCCT GTGTCACCGC TTGATGCTAA ACCCTCAGCA TGTGCAGCTC 
CTTTTTGACA ATGAAGTTCT CCCTGATCAC ATGACAATGA AGCAGATATG GCTCTCCCGC 
TGGTTCGGCA AGCCATCCCC TTTGCTTTTA CAATACAGTG TGAAAGAGAA GAGGAGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PCGF1 ( NM_032673.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_116062.2 Homo sapiens polycomb group ring finger 1 (PCGF1), mRNA.

Price & Availability↑

CloneID	OHu05078
Clone ID Related Accession (Same CDS sequence)	NM_032673.3 , NM_032673.2
Accession Version	NM_032673.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 780bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-15
Organism	Homo sapiens(human)
Product	polycomb group RING finger protein 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BU602498.1 and BC004952.1. On Jun 17, 2006 this sequence version replaced NM_032673.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.595382.1, ERR279832.10185.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGTCTC CTCAGGGGGG CCAGATTGCG ATCGCGATGA GGCTTCGGAA CCAGCTCCAG 
TCAGTGTACA AGATGGACCC GCTACGGAAC GAGGAGGAGG TTCGAGTGAA GATCAAAGAC 
TTGAATGAAC ACATTGTTTG CTGCCTATGC GCCGGCTACT TCGTGGATGC CACCACCATC 
ACAGAGTGTC TTCATACTTT CTGCAAGAGT TGTATTGTGA AGTACCTCCA AACTAGCAAG 
TACTGCCCCA TGTGCAACAT TAAGATCCAC GAGACACAGC CACTGCTCAA CCTCAAACTG 
GACCGGGTCA TGCAGGACAT CGTGTATAAG CTGGTGCCTG GCTTGCAAGA CAGTGAAGAG 
AAACGGATTC GGGAATTCTA CCAGTCCCGA GGTTTGGACC GGGTCACCCA GCCCACTGGG 
GAAGAGCCAG CACTGAGCAA CCTCGGCCTC CCCTTCAGCA GCTTTGACCA CTCTAAAGCC 
CACTACTATC GCTATGATGA GCAGTTGAAC CTGTGCCTGG AGCGGCTGAG TTCTGGCAAA 
GACAAGAATA AAAGCGTCCT GCAGAACAAG TATGTCCGAT GTTCTGTTAG AGCTGAGGTA 
CGCCATCTCC GGAGGGTCCT GTGTCACCGC TTGATGCTAA ACCCTCAGCA TGTGCAGCTC 
CTTTTTGACA ATGAAGTTCT CCCTGATCAC ATGACAATGA AGCAGATATG GCTCTCCCGC 
TGGTTCGGCA AGCCATCCCC TTTGCTTTTA CAATACAGTG TGAAAGAGAA GAGGAGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_116062.2
CDS	27..806
Translation	MASPQGGQIAIAMRLRNQLQSVYKMDPLRNEEEVRVKIKDLNEHIVCCLCAGYFVDATTITECLHTFCKSCIVKYLQTSKYCPMCNIKIHETQPLLNLKLDRVMQDIVYKLVPGLQDSEEKRIREFYQSRGLDRVTQPTGEEPALSNLGLPFSSFDHSKAHYYRYDEQLNLCLERLSSGKDKNKSVLQNKYVRCSVRAEVRHLRRVLCHRLMLNPQHVQLLFDNEVLPDHMTMKQIWLSRWFGKPSPLLLQYSVKEKRR

Target ORF information:

RefSeq Version	NM_032673.2
Organism	Homo sapiens(human)
Definition	Homo sapiens polycomb group ring finger 1 (PCGF1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_032673.2

ORF Insert Sequence:

ATGGCGTCTC CTCAGGGGGG CCAGATTGCG ATCGCGATGA GGCTTCGGAA CCAGCTCCAG 
TCAGTGTACA AGATGGACCC GCTACGGAAC GAGGAGGAGG TTCGAGTGAA GATCAAAGAC 
TTGAATGAAC ACATTGTTTG CTGCCTATGC GCCGGCTACT TCGTGGATGC CACCACCATC 
ACAGAGTGTC TTCATACTTT CTGCAAGAGT TGTATTGTGA AGTACCTCCA AACTAGCAAG 
TACTGCCCCA TGTGCAACAT TAAGATCCAC GAGACACAGC CACTGCTCAA CCTCAAACTG 
GACCGGGTCA TGCAGGACAT CGTGTATAAG CTGGTGCCTG GCTTGCAAGA CAGTGAAGAG 
AAACGGATTC GGGAATTCTA CCAGTCCCGA GGTTTGGACC GGGTCACCCA GCCCACTGGG 
GAAGAGCCAG CACTGAGCAA CCTCGGCCTC CCCTTCAGCA GCTTTGACCA CTCTAAAGCC 
CACTACTATC GCTATGATGA GCAGTTGAAC CTGTGCCTGG AGCGGCTGAG TTCTGGCAAA 
GACAAGAATA AAAGCGTCCT GCAGAACAAG TATGTCCGAT GTTCTGTTAG AGCTGAGGTA 
CGCCATCTCC GGAGGGTCCT GTGTCACCGC TTGATGCTAA ACCCTCAGCA TGTGCAGCTC 
CTTTTTGACA ATGAAGTTCT CCCTGATCAC ATGACAATGA AGCAGATATG GCTCTCCCGC 
TGGTTCGGCA AGCCATCCCC TTTGCTTTTA CAATACAGTG TGAAAGAGAA GAGGAGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PCGF1 ( XM_024453181.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024308949.1 Homo sapiens polycomb group ring finger 1 (PCGF1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu35640
Clone ID Related Accession (Same CDS sequence)	XM_024453181.1
Accession Version	XM_024453181.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 531bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	polycomb group RING finger protein 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTGCAACA TTAAGATCCA CGAGACACAG CCACTGCTCA ACCTCAAACT GGACCGGGTC 
ATGCAGGACA TCGTGTATAA GCTGGTGCCT GGCTTGCAAG ACAGTGAAGA GAAACGGATT 
CGGGAATTCT ACCAGTCCCG AGGTTTGGAC CGGGTCACCC AGCCCACTGG GGAAGAGCCA 
GCACTGAGCA ACCTCGGCCT CCCCTTCAGC AGCTTTGACC ACTCTAAAGC CCACTACTAT 
CGCTATGATG AGCAGTTGAA CCTGTGCCTG GAGCGGCTGA GTTCTGGCAA AGACAAGAAT 
AAAAGCGTCC TGCAGAACAA GTATGTCCGA TGTTCTGTTA GAGCTGAGGT ACGCCATCTC 
CGGAGGGTCC TGTGTCACCG CTTGATGCTA AACCCTCAGC ATGTGCAGCT CCTTTTTGAC 
AATGAAGTTC TCCCTGATCA CATGACAATG AAGCAGATAT GGCTCTCCCG CTGGTTCGGC 
AAGCCATCCC CTTTGCTTTT ACAATACAGT GTGAAAGAGA AGAGGAGGTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024308949.1
CDS	310..840
Translation	MCNIKIHETQPLLNLKLDRVMQDIVYKLVPGLQDSEEKRIREFYQSRGLDRVTQPTGEEPALSNLGLPFSSFDHSKAHYYRYDEQLNLCLERLSSGKDKNKSVLQNKYVRCSVRAEVRHLRRVLCHRLMLNPQHVQLLFDNEVLPDHMTMKQIWLSRWFGKPSPLLLQYSVKEKRR

Target ORF information:

RefSeq Version	XM_024453181.1
Organism	Homo sapiens(human)
Definition	Homo sapiens polycomb group ring finger 1 (PCGF1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024453181.1

ORF Insert Sequence:

ATGTGCAACA TTAAGATCCA CGAGACACAG CCACTGCTCA ACCTCAAACT GGACCGGGTC 
ATGCAGGACA TCGTGTATAA GCTGGTGCCT GGCTTGCAAG ACAGTGAAGA GAAACGGATT 
CGGGAATTCT ACCAGTCCCG AGGTTTGGAC CGGGTCACCC AGCCCACTGG GGAAGAGCCA 
GCACTGAGCA ACCTCGGCCT CCCCTTCAGC AGCTTTGACC ACTCTAAAGC CCACTACTAT 
CGCTATGATG AGCAGTTGAA CCTGTGCCTG GAGCGGCTGA GTTCTGGCAA AGACAAGAAT 
AAAAGCGTCC TGCAGAACAA GTATGTCCGA TGTTCTGTTA GAGCTGAGGT ACGCCATCTC 
CGGAGGGTCC TGTGTCACCG CTTGATGCTA AACCCTCAGC ATGTGCAGCT CCTTTTTGAC 
AATGAAGTTC TCCCTGATCA CATGACAATG AAGCAGATAT GGCTCTCCCG CTGGTTCGGC 
AAGCCATCCC CTTTGCTTTT ACAATACAGT GTGAAAGAGA AGAGGAGGTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

MicroRNA?320a inhibition decreases insulin?induced KGN cell proliferation and apoptosis by targeting PCGF1.
Molecular medicine reports16(4)5706-5712(2017 Oct)
Yang L,Li Y,Wang X,Liu Y,Yang L

NSPc1 promotes cancer stem cell self-renewal by repressing the synthesis of all-trans retinoic acid via targeting RDH16 in malignant glioma.
Oncogene36(33)4706-4718(2017 Aug)
Hu PS,Xia QS,Wu F,Li DK,Qi YJ,Hu Y,Wei ZZ,Li SS,Tian NY,Wei QF,Shen LJ,Yin B,Jiang T,Yuan JG,Qiang BQ,Han W,Peng XZ

Architecture of the human interactome defines protein communities and disease networks.
Nature545(7655)505-509(2017 05)
Huttlin EL,Bruckner RJ,Paulo JA,Cannon JR,Ting L,Baltier K,Colby G,Gebreab F,Gygi MP,Parzen H,Szpyt J,Tam S,Zarraga G,Pontano-Vaites L,Swarup S,White AE,Schweppe DK,Rad R,Erickson BK,Obar RA,Guruharsha KG,Li K,Artavanis-Tsakonas S,Gygi SP,Harper JW

A High-Density Map for Navigating the Human Polycomb Complexome.
Cell reports17(2)583-595(2016 10)
Hauri S,Comoglio F,Seimiya M,Gerstung M,Glatter T,Hansen K,Aebersold R,Paro R,Gstaiger M,Beisel C

EZH2 and BCL6 Cooperate to Assemble CBX8-BCOR Complex to Repress Bivalent Promoters, Mediate Germinal Center Formation and Lymphomagenesis.
Cancer cell30(2)197-213(2016 Aug)
B?guelin W,Teater M,Gearhart MD,Calvo Fern?ndez MT,Goldstein RL,C?rdenas MG,Hatzi K,Rosen M,Shen H,Corcoran CM,Hamline MY,Gascoyne RD,Levine RL,Abdel-Wahab O,Licht JD,Shaknovich R,Elemento O,Bardwell VJ,Melnick AM

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PCGF1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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