Gene Symbol | KLF11 |
Entrez Gene ID | 8462 |
Full Name | Kruppel like factor 11 |
Synonyms | FKLF,FKLF1,MODY7,TIEG2,Tieg3 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | The protein encoded by this gene is a zinc finger transcription factor that binds to SP1-like sequences in epsilon- and gamma-globin gene promoters. This binding inhibits cell growth and causes apoptosis. Defects in this gene are a cause of maturity-onset diabetes of the young type 7 (MODY7). Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Apr 2010]. |
Disorder MIM: | |
Disorder Html: | Maturity-onset diabetes of the young, type VII, 610508 (3) |