STARD5 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	STARD5
Entrez Gene ID	80765
Full Name	StAR related lipid transfer domain containing 5
General protein information	Preferred Names StAR related lipid transfer domain containing 5 Names stAR-related lipid transfer protein 5 START domain containing 5 START domain-containing protein 5 StAR-related lipid transfer (START) domain containing 5
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 15 Map Location: 15q25.1
Summary	Proteins containing a steroidogenic acute regulatory-related lipid transfer (START) domain are often involved in the trafficking of lipids and cholesterol between diverse intracellular membranes. This gene is a member of the StarD subfamily that encodes START-related lipid transfer proteins. The protein encoded by this gene is a cholesterol transporter and is also able to bind and transport other sterol-derived molecules related to the cholesterol/bile acid biosynthetic pathways such as 25-hydroxycholesterol. Its expression is upregulated during endoplasmic reticulum (ER) stress. The protein is thought to act as a cytosolic sterol transporter that moves cholesterol between intracellular membranes such as from the cytoplasm to the ER and from the ER to the Golgi apparatus. Alternative splicing of this gene produces multiple transcript variants. [provided by RefSeq, Jan 2016].
Disorder MIM:	607050

mRNA and Protein(s)

mRNA	Protein	Name
XM_017022639.1	XP_016878128.1	stAR-related lipid transfer protein 5 isoform X1
XM_006720703.1	XP_006720766.1	stAR-related lipid transfer protein 5 isoform X2
NM_181900.3	NP_871629.1	stAR-related lipid transfer protein 5
NM_181900.2	NP_871629.1	stAR-related lipid transfer protein 5

Pathways from BioSystems

Homologies

	STARD5	XP_001110144.1
Canis lupus familiaris (dog)	STARD5	XP_005618465.1
Rattus norvegicus (Norway rat)	Stard5	NP_001178940.1
Gallus gallus (chicken)	STARD5	XP_001232612.1
Bos taurus (cattle)	STARD5	NP_001073734.1
Danio rerio (zebrafish)	LOC796844	XP_001337240.3
Mus musculus (house mouse)	Stard5	NP_075866.2
Homo sapiens (human)	STARD5	NP_871629.1
Pan troglodytes (chimpanzee)	STARD5	XP_523136.2
Xenopus tropicalis (tropical clawed frog)	stard5	XP_002932294.1

Gene Ontology
Bibliography

Related articles in PubMed

The StarD4 subfamily of steroidogenic acute regulatory-related lipid transfer (START) domain proteins: new players in cholesterol metabolism.
Calderon-Dominguez M, Gil G, Medina MA, Pandak WM, Rodr?guez-Agudo D
The international journal of biochemistry & cell biology4964-8(2014 Apr)

Thermodynamic and solution state NMR characterization of the binding of secondary and conjugated bile acids to STARD5.
L?tourneau D, Lorin A, Lefebvre A, Cabana J, Lavigne P, LeHoux JG
Biochimica et biophysica acta1831(11)1589-99(2013 Nov)

Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S,
Diabetes care33(10)2250-3(2010 Oct)

New genetic associations detected in a host response study to hepatitis B vaccine.
Davila S, Froeling FE, Tan A, Bonnard C, Boland GJ, Snippe H, Hibberd ML, Seielstad M
Genes and immunity11(3)232-8(2010 Apr)

Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD, , ,
American journal of human genetics85(5)628-42(2009 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Studies show the 3 steroidogenic acute regulatory-related lipid transfer (START) domain proteins StarD4, StarD5 and StarD6 have a similar lipid binding pocket specific for sterols (cholesterol in particular), but differing regulation and localization.
Title: The StarD4 subfamily of steroidogenic acute regulatory-related lipid transfer (START) domain proteins: new players in cholesterol metabolism.

Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
Title: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.

Observational study of gene-disease association. (HuGE Navigator)
Title: New genetic associations detected in a host response study to hepatitis B vaccine.

Observational study of gene-disease association. (HuGE Navigator)
Title: Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.

Data support STARD5 functioning in kidney, specifically within proximal tubule cells, and suggest a role in ER-associated cholesterol transport.
Title: Steroidogenic acute regulatory-related lipid transfer domain protein 5 localization and regulation in renal tubules.

The following STARD5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the STARD5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu07617	NM_181900.3 Latest version!	Homo sapiens StAR related lipid transfer domain containing 5 (STARD5), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu48603	XM_006720703.1 Latest version!	Homo sapiens StAR related lipid transfer domain containing 5 (STARD5), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu85700	XM_017022639.1 Latest version!	Homo sapiens StAR related lipid transfer domain containing 5 (STARD5), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
View Old Accession Versions >>
OHu07617	NM_181900.2	Homo sapiens StAR related lipid transfer domain containing 5 (STARD5), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

STARD5 ( NM_181900.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_871629.1 Homo sapiens StAR related lipid transfer domain containing 5 (STARD5), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu07617
Clone ID Related Accession (Same CDS sequence)	NM_181900.3 , NM_181900.2
Accession Version	NM_181900.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 642bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-26
Organism	Homo sapiens(human)
Product	stAR-related lipid transfer protein 5
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL137657.1, BC004365.1, AK097024.1, AK026352.1 and AC103858.2. On Nov 23, 2018 this sequence version replaced NM_181900.2. Transcript Variant: This variant (1) represents the longer transcript. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DA115300.1, SRR1163658.299406.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000302824.7/ ENSP00000304032.6 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGACCCGG CGCTGGCAGC CCAGATGAGC GAGGCTGTGG CCGAGAAGAT GCTCCAGTAC 
CGGCGGGACA CAGCAGGCTG GAAGATTTGC CGGGAAGGCA ATGGAGTTTC AGTTTCCTGG 
AGGCCATCTG TGGAGTTTCC AGGGAACCTG TACCGAGGAG AAGGCATTGT ATATGGGACA 
CTAGAGGAGG TGTGGGACTG TGTGAAGCCA GCTGTTGGAG GCCTACGAGT GAAGTGGGAT 
GAGAATGTGA CCGGTTTTGA AATTATCCAA AGCATCACTG ACACCCTGTG TGTAAGCAGA 
ACCTCCACTC CCTCCGCTGC CATGAAGCTC ATTTCTCCCA GAGATTTTGT GGACTTGGTG 
CTAGTCAAGA GATATGAGGA TGGGACCATC AGTTCCAACG CCACCCATGT GGAGCATCCG 
TTATGTCCCC CGAAGCCAGG TTTTGTGAGA GGATTTAACC ATCCTTGTGG TTGCTTCTGT 
GAACCTCTTC CAGGGGAACC CACCAAGACC AACCTGGTCA CATTCTTCCA TACCGACCTC 
AGCGGTTACC TCCCACAGAA CGTGGTGGAC TCCTTCTTCC CCCGCAGCAT GACCCGGTTT 
TATGCCAACC TTCAGAAAGC AGTGAAGCAA TTCCATGAGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_871629.1
CDS	43..684
Translation	MDPALAAQMSEAVAEKMLQYRRDTAGWKICREGNGVSVSWRPSVEFPGNLYRGEGIVYGTLEEVWDCVKPAVGGLRVKWDENVTGFEIIQSITDTLCVSRTSTPSAAMKLISPRDFVDLVLVKRYEDGTISSNATHVEHPLCPPKPGFVRGFNHPCGCFCEPLPGEPTKTNLVTFFHTDLSGYLPQNVVDSFFPRSMTRFYANLQKAVKQFHE

Target ORF information:

RefSeq Version	NM_181900.3
Organism	Homo sapiens(human)
Definition	Homo sapiens StAR related lipid transfer domain containing 5 (STARD5), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_181900.3

ORF Insert Sequence:

ATGGACCCGG CGCTGGCAGC CCAGATGAGC GAGGCTGTGG CCGAGAAGAT GCTCCAGTAC 
CGGCGGGACA CAGCAGGCTG GAAGATTTGC CGGGAAGGCA ATGGAGTTTC AGTTTCCTGG 
AGGCCATCTG TGGAGTTTCC AGGGAACCTG TACCGAGGAG AAGGCATTGT ATATGGGACA 
CTAGAGGAGG TGTGGGACTG TGTGAAGCCA GCTGTTGGAG GCCTACGAGT GAAGTGGGAT 
GAGAATGTGA CCGGTTTTGA AATTATCCAA AGCATCACTG ACACCCTGTG TGTAAGCAGA 
ACCTCCACTC CCTCCGCTGC CATGAAGCTC ATTTCTCCCA GAGATTTTGT GGACTTGGTG 
CTAGTCAAGA GATATGAGGA TGGGACCATC AGTTCCAACG CCACCCATGT GGAGCATCCG 
TTATGTCCCC CGAAGCCAGG TTTTGTGAGA GGATTTAACC ATCCTTGTGG TTGCTTCTGT 
GAACCTCTTC CAGGGGAACC CACCAAGACC AACCTGGTCA CATTCTTCCA TACCGACCTC 
AGCGGTTACC TCCCACAGAA CGTGGTGGAC TCCTTCTTCC CCCGCAGCAT GACCCGGTTT 
TATGCCAACC TTCAGAAAGC AGTGAAGCAA TTCCATGAGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

STARD5 ( NM_181900.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_871629.1 Homo sapiens StAR related lipid transfer domain containing 5 (STARD5), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu07617
Clone ID Related Accession (Same CDS sequence)	NM_181900.3 , NM_181900.2
Accession Version	NM_181900.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 642bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-30
Organism	Homo sapiens(human)
Product	stAR-related lipid transfer protein 5
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL137657.1, BC004365.1, AK097024.1 and AK026352.1. On Dec 1, 2003 this sequence version replaced NM_181900.1. Transcript Variant: This variant (1) represents the longer transcript. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163658.299406.1, ERR279861.3120.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGACCCGG CGCTGGCAGC CCAGATGAGC GAGGCTGTGG CCGAGAAGAT GCTCCAGTAC 
CGGCGGGACA CAGCAGGCTG GAAGATTTGC CGGGAAGGCA ATGGAGTTTC AGTTTCCTGG 
AGGCCATCTG TGGAGTTTCC AGGGAACCTG TACCGAGGAG AAGGCATTGT ATATGGGACA 
CTAGAGGAGG TGTGGGACTG TGTGAAGCCA GCTGTTGGAG GCCTACGAGT GAAGTGGGAT 
GAGAATGTGA CCGGTTTTGA AATTATCCAA AGCATCACTG ACACCCTGTG TGTAAGCAGA 
ACCTCCACTC CCTCCGCTGC CATGAAGCTC ATTTCTCCCA GAGATTTTGT GGACTTGGTG 
CTAGTCAAGA GATATGAGGA TGGGACCATC AGTTCCAACG CCACCCATGT GGAGCATCCG 
TTATGTCCCC CGAAGCCAGG TTTTGTGAGA GGATTTAACC ATCCTTGTGG TTGCTTCTGT 
GAACCTCTTC CAGGGGAACC CACCAAGACC AACCTGGTCA CATTCTTCCA TACCGACCTC 
AGCGGTTACC TCCCACAGAA CGTGGTGGAC TCCTTCTTCC CCCGCAGCAT GACCCGGTTT 
TATGCCAACC TTCAGAAAGC AGTGAAGCAA TTCCATGAGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_871629.1
CDS	85..726
Translation	MDPALAAQMSEAVAEKMLQYRRDTAGWKICREGNGVSVSWRPSVEFPGNLYRGEGIVYGTLEEVWDCVKPAVGGLRVKWDENVTGFEIIQSITDTLCVSRTSTPSAAMKLISPRDFVDLVLVKRYEDGTISSNATHVEHPLCPPKPGFVRGFNHPCGCFCEPLPGEPTKTNLVTFFHTDLSGYLPQNVVDSFFPRSMTRFYANLQKAVKQFHE

Target ORF information:

RefSeq Version	NM_181900.2
Organism	Homo sapiens(human)
Definition	Homo sapiens StAR related lipid transfer domain containing 5 (STARD5), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_181900.2

ORF Insert Sequence:

ATGGACCCGG CGCTGGCAGC CCAGATGAGC GAGGCTGTGG CCGAGAAGAT GCTCCAGTAC 
CGGCGGGACA CAGCAGGCTG GAAGATTTGC CGGGAAGGCA ATGGAGTTTC AGTTTCCTGG 
AGGCCATCTG TGGAGTTTCC AGGGAACCTG TACCGAGGAG AAGGCATTGT ATATGGGACA 
CTAGAGGAGG TGTGGGACTG TGTGAAGCCA GCTGTTGGAG GCCTACGAGT GAAGTGGGAT 
GAGAATGTGA CCGGTTTTGA AATTATCCAA AGCATCACTG ACACCCTGTG TGTAAGCAGA 
ACCTCCACTC CCTCCGCTGC CATGAAGCTC ATTTCTCCCA GAGATTTTGT GGACTTGGTG 
CTAGTCAAGA GATATGAGGA TGGGACCATC AGTTCCAACG CCACCCATGT GGAGCATCCG 
TTATGTCCCC CGAAGCCAGG TTTTGTGAGA GGATTTAACC ATCCTTGTGG TTGCTTCTGT 
GAACCTCTTC CAGGGGAACC CACCAAGACC AACCTGGTCA CATTCTTCCA TACCGACCTC 
AGCGGTTACC TCCCACAGAA CGTGGTGGAC TCCTTCTTCC CCCGCAGCAT GACCCGGTTT 
TATGCCAACC TTCAGAAAGC AGTGAAGCAA TTCCATGAGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

STARD5 ( XM_006720703.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_006720766.1 Homo sapiens StAR related lipid transfer domain containing 5 (STARD5), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu48603
Clone ID Related Accession (Same CDS sequence)	XM_006720703.1
Accession Version	XM_006720703.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 441bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	stAR-related lipid transfer protein 5 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000015.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACCCGG CGCTGGCAGC CCAGATGAGC GAGGCTGTGG CCGAGAAGAT GCTCCAGTAC 
CGGCGGGACA CAGCAGGCTG GAAGATTTGC CGGGAAGGCG TGAGTGAGGA GCTGGGCGGG 
AAGGGGTCGC GGAGACGGCT TCGTGGAGCC CGGGTCCCCA GAAGCCCCCA AGCGCCTCCT 
CTCCCCGTTG TTTTCTGCTC CCCAATCCCC TGGACCCGAT TGAGAGGGAT TCCAATGGGG 
ATTGTTTTCT TCTTTAAAAA AAAGATTGGG CCTGTTATGC TCACAATGAC TTCAGGTGAA 
TGGAGTTTCA GTTTCCTGGA GGCCATCTGT GGAGTTTCCA GGGAACCTGT ACCGAGGAGA 
AGGCATTGTA TATGGGACAC TAGAGGAGGT GTGGGACTGT GTGAAGCCAG CTGTTGGAGG 
CCTACGAGTG AAGTGGGATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006720766.1
CDS	43..483
Translation	MDPALAAQMSEAVAEKMLQYRRDTAGWKICREGVSEELGGKGSRRRLRGARVPRSPQAPPLPVVFCSPIPWTRLRGIPMGIVFFFKKKIGPVMLTMTSGEWSFSFLEAICGVSREPVPRRRHCIWDTRGGVGLCEASCWRPTSEVG

Target ORF information:

RefSeq Version	XM_006720703.1
Organism	Homo sapiens(human)
Definition	Homo sapiens StAR related lipid transfer domain containing 5 (STARD5), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006720703.1

ORF Insert Sequence:

ATGGACCCGG CGCTGGCAGC CCAGATGAGC GAGGCTGTGG CCGAGAAGAT GCTCCAGTAC 
CGGCGGGACA CAGCAGGCTG GAAGATTTGC CGGGAAGGCG TGAGTGAGGA GCTGGGCGGG 
AAGGGGTCGC GGAGACGGCT TCGTGGAGCC CGGGTCCCCA GAAGCCCCCA AGCGCCTCCT 
CTCCCCGTTG TTTTCTGCTC CCCAATCCCC TGGACCCGAT TGAGAGGGAT TCCAATGGGG 
ATTGTTTTCT TCTTTAAAAA AAAGATTGGG CCTGTTATGC TCACAATGAC TTCAGGTGAA 
TGGAGTTTCA GTTTCCTGGA GGCCATCTGT GGAGTTTCCA GGGAACCTGT ACCGAGGAGA 
AGGCATTGTA TATGGGACAC TAGAGGAGGT GTGGGACTGT GTGAAGCCAG CTGTTGGAGG 
CCTACGAGTG AAGTGGGATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

STARD5 ( XM_017022639.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016878128.1 Homo sapiens StAR related lipid transfer domain containing 5 (STARD5), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu85700
Clone ID Related Accession (Same CDS sequence)	XM_017022639.1
Accession Version	XM_017022639.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 579bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	stAR-related lipid transfer protein 5 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000015.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTCCACC TTCTAGTCCT TAGATACAAT CTCAAGATAA CAAGTTTGAT TGATGCGTTG 
GGGTCAAATT CCTTTTCGTG CTCCAGGTAC CGAGGAGAAG GCATTGTATA TGGGACACTA 
GAGGAGGTGT GGGACTGTGT GAAGCCAGCT GTTGGAGGCC TACGAGTGAA GTGGGATGAG 
AATGTGACCG GTTTTGAAAT TATCCAAAGC ATCACTGACA CCCTGTGTGT AAGCAGAACC 
TCCACTCCCT CCGCTGCCAT GAAGCTCATT TCTCCCAGAG ATTTTGTGGA CTTGGTGCTA 
GTCAAGAGAT ATGAGGATGG GACCATCAGT TCCAACGCCA CCCATGTGGA GCATCCGTTA 
TGTCCCCCGA AGCCAGGTTT TGTGAGAGGA TTTAACCATC CTTGTGGTTG CTTCTGTGAA 
CCTCTTCCAG GGGAACCCAC CAAGACCAAC CTGGTCACAT TCTTCCATAC CGACCTCAGC 
GGTTACCTCC CACAGAACGT GGTGGACTCC TTCTTCCCCC GCAGCATGAC CCGGTTTTAT 
GCCAACCTTC AGAAAGCAGT GAAGCAATTC CATGAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016878128.1
CDS	663..1241
Translation	MVHLLVLRYNLKITSLIDALGSNSFSCSRYRGEGIVYGTLEEVWDCVKPAVGGLRVKWDENVTGFEIIQSITDTLCVSRTSTPSAAMKLISPRDFVDLVLVKRYEDGTISSNATHVEHPLCPPKPGFVRGFNHPCGCFCEPLPGEPTKTNLVTFFHTDLSGYLPQNVVDSFFPRSMTRFYANLQKAVKQFHE

Target ORF information:

RefSeq Version	XM_017022639.1
Organism	Homo sapiens(human)
Definition	Homo sapiens StAR related lipid transfer domain containing 5 (STARD5), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017022639.1

ORF Insert Sequence:

ATGGTCCACC TTCTAGTCCT TAGATACAAT CTCAAGATAA CAAGTTTGAT TGATGCGTTG 
GGGTCAAATT CCTTTTCGTG CTCCAGGTAC CGAGGAGAAG GCATTGTATA TGGGACACTA 
GAGGAGGTGT GGGACTGTGT GAAGCCAGCT GTTGGAGGCC TACGAGTGAA GTGGGATGAG 
AATGTGACCG GTTTTGAAAT TATCCAAAGC ATCACTGACA CCCTGTGTGT AAGCAGAACC 
TCCACTCCCT CCGCTGCCAT GAAGCTCATT TCTCCCAGAG ATTTTGTGGA CTTGGTGCTA 
GTCAAGAGAT ATGAGGATGG GACCATCAGT TCCAACGCCA CCCATGTGGA GCATCCGTTA 
TGTCCCCCGA AGCCAGGTTT TGTGAGAGGA TTTAACCATC CTTGTGGTTG CTTCTGTGAA 
CCTCTTCCAG GGGAACCCAC CAAGACCAAC CTGGTCACAT TCTTCCATAC CGACCTCAGC 
GGTTACCTCC CACAGAACGT GGTGGACTCC TTCTTCCCCC GCAGCATGAC CCGGTTTTAT 
GCCAACCTTC AGAAAGCAGT GAAGCAATTC CATGAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The StarD4 subfamily of steroidogenic acute regulatory-related lipid transfer (START) domain proteins: new players in cholesterol metabolism.
The international journal of biochemistry & cell biology4964-8(2014 Apr)
Calderon-Dominguez M,Gil G,Medina MA,Pandak WM,Rodr?guez-Agudo D

Thermodynamic and solution state NMR characterization of the binding of secondary and conjugated bile acids to STARD5.
Biochimica et biophysica acta1831(11)1589-99(2013 Nov)
L?tourneau D,Lorin A,Lefebvre A,Cabana J,Lavigne P,LeHoux JG

Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Diabetes care33(10)2250-3(2010 Oct)
Bailey SD,Xie C,Do R,Montpetit A,Diaz R,Mohan V,Keavney B,Yusuf S,Gerstein HC,Engert JC,Anand S,

New genetic associations detected in a host response study to hepatitis B vaccine.
Genes and immunity11(3)232-8(2010 Apr)
Davila S,Froeling FE,Tan A,Bonnard C,Boland GJ,Snippe H,Hibberd ML,Seielstad M

Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
American journal of human genetics85(5)628-42(2009 Nov)
Talmud PJ,Drenos F,Shah S,Shah T,Palmen J,Verzilli C,Gaunt TR,Pallas J,Lovering R,Li K,Casas JP,Sofat R,Kumari M,Rodriguez S,Johnson T,Newhouse SJ,Dominiczak A,Samani NJ,Caulfield M,Sever P,Stanton A,Shields DC,Padmanabhan S,Melander O,Hastie C,Delles C,Ebrahim S,Marmot MG,Smith GD,Lawlor DA,Munroe PB,Day IN,Kivimaki M,Whittaker J,Humphries SE,Hingorani AD,,,

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STARD5 cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

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Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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