Gene Symbol | EDEM3 |
Entrez Gene ID | 80267 |
Full Name | ER degradation enhancing alpha-mannosidase like protein 3 |
Synonyms | C1orf22 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | Quality control in the endoplasmic reticulum (ER) ensures that only properly folded proteins are retained in the cell through recognition and degradation of misfolded or unassembled proteins. EDEM3 belongs to a group of proteins that accelerate degradation of misfolded glycoproteins in the ER (Hirao et al., 2006 [PubMed 16431915]).[supplied by OMIM, Mar 2008]. |
Disorder MIM: |